{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T01:52:12Z","timestamp":1792806732252,"version":"4.5.0"},"reference-count":41,"publisher":"American Medical Association (AMA)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JAMA Netw Open"],"abstract":"\n Importance<\/jats:title>\n The National Cancer Institute comprehensive cancer centers (CCCs) lack spatial and temporal evaluation of their self-designated catchment areas.<\/jats:p>\n <\/jats:sec>\n \n Objective<\/jats:title>\n To identify disparities in cancer stage at diagnosis within and outside a CCC\u2019s catchment area across a 10-year period using spatial and statistical analyses.<\/jats:p>\n <\/jats:sec>\n \n Design, Setting, and Participants<\/jats:title>\n This cross-sectional, population-based study conducted between 2010 and 2019 utilized cancer registry data for the Johns Hopkins Sidney Kimmel CCC (SKCCC). Eligible participants included patients with cancer in the contiguous US who received treatment for cancer, a diagnosis of cancer, or both at SKCCC. Patients were geocoded to zip code tabulation areas (ZCTAs). Individual-level variables included sociodemographic characteristics, smoking and alcohol use, treatment type, cancer site, and insurance type. Data analysis was performed between March and July 2023.<\/jats:p>\n <\/jats:sec>\n \n Exposures<\/jats:title>\n Distance between SKCCC and ZCTAs were computed to generate a catchment area of the closest 75% of patients and outer zones in 5% increments for comparison.<\/jats:p>\n <\/jats:sec>\n \n Main Outcomes and Measures<\/jats:title>\n The primary outcome was cancer stage at diagnosis, defined as early-stage, late-stage, or unknown stage. Multinomial logistic regression was used to determine associations of catchment area with stage at diagnosis.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n This study had a total of 94\u202f007 participants (46\u202f009 male [48.94%] and 47\u202f998 female [51.06%]; 30\u202f195 aged 22-45 years [32.12%]; 4209 Asian [4.48%]; 2408 Hispanic [2.56%]; 16\u202f004 non-Hispanic Black [17.02%]; 69\u202f052 non-Hispanic White [73.45%]; and 2334 with other or unknown race or ethnicity [2.48%]), including 47\u202f245 patients (50.26%) who received a diagnosis of early-stage cancer, 19\u202f491 (20.73%) who received a diagnosis of late-stage cancer , and 27\u202f271 (29.01%) with unknown stage. Living outside the main catchment area was associated with higher odds of late-stage cancers for those who received only a diagnosis (odds ratio [OR], 1.50; 95% CI, 1.10-2.05) or only treatment (OR, 1.44; 95% CI, 1.28-1.61) at SKCCC. Non-Hispanic Black patients (OR, 1.16; 95% CI, 1.10-1.23) and those with Medicaid (OR, 1.65; 95% CI, 1.46-1.86) and no insurance at time of treatment (OR, 2.12; 95% CI, 1.79-2.51) also had higher odds of receiving a late-stage cancer diagnosis.<\/jats:p>\n <\/jats:sec>\n \n Conclusions and Relevance<\/jats:title>\n In this cross-sectional study of CCC data from 2010 to 2019, patients residing outside the main catchment area, non-Hispanic Black patients, and patients with Medicaid or no insurance had higher odds of late-stage diagnoses. These findings suggest that disadvantaged populations and those living outside of the main catchment area of a CCC may face barriers to screening and treatment. Care-sharing agreements among CCCs could address these issues.<\/jats:p>\n <\/jats:sec>","DOI":"10.1001\/jamanetworkopen.2024.9474","type":"journal-article","created":{"date-parts":[[2024,5,2]],"date-time":"2024-05-02T11:33:23Z","timestamp":1714649603000},"page":"e249474","source":"Crossref","is-referenced-by-count":20,"title":["Disparities in Cancer Stage Outcomes by Catchment Areas for a Comprehensive Cancer Center"],"prefix":"10.1001","volume":"7","author":[{"given":"Michael R.","family":"Desjardins","sequence":"first","affiliation":[{"name":"Department of Epidemiology and Spatial Science for Public Health Center, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Norma F.","family":"Kanarek","sequence":"additional","affiliation":[{"name":"Department of Environmental Health Sciences, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland"},{"name":"Department of Oncology, Johns Hopkins 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