{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T18:57:40Z","timestamp":1793041060711,"version":"4.5.0"},"reference-count":54,"publisher":"American Medical Association (AMA)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JAMA Netw Open"],"abstract":"<jats:sec id=\"ab-zoi250004-4\"><jats:title>Importance<\/jats:title><jats:p>Some US populations experience perceived discrimination in health care settings (PDHS) that may lead to delaying health care and worse health outcomes. It is crucial to understand potential mechanisms, such as patient-clinician communication (PCC), that may reduce these disparities.<\/jats:p><\/jats:sec><jats:sec id=\"ab-zoi250004-5\"><jats:title>Objective<\/jats:title><jats:p>To examine PCC as a mediating pathway between PDHS and health care delays due to nervousness about seeing a health care professional while considering the moderating roles of age and race and ethnicity.<\/jats:p><\/jats:sec><jats:sec id=\"ab-zoi250004-6\"><jats:title>Design, Setting, and Participants<\/jats:title><jats:p>This cross-sectional study examined data from the All of Us Research Program between May 31, 2017, and April 30, 2022. Included participants were adults aged 18 years or older with type 2 diabetes and\/or hypertension. The data analysis was performed between February 20 and April 29, 2024.<\/jats:p><\/jats:sec><jats:sec id=\"ab-zoi250004-7\"><jats:title>Exposure<\/jats:title><jats:p>Perceived discrimination in the health care setting.<\/jats:p><\/jats:sec><jats:sec id=\"ab-zoi250004-8\"><jats:title>Main Outcome and Measures<\/jats:title><jats:p>The study outcome was health care delays due to being nervous about seeing a health care professional. The association between PDHS and health care delays was examined through PCC using a structural equation model with moderated mediation analysis.<\/jats:p><\/jats:sec><jats:sec id=\"ab-zoi250004-9\"><jats:title>Results<\/jats:title><jats:p>The analytic sample comprised 25\u202f581 participants (mean [SD] age, 62.4 [12.8] years; 58.1% women; and 9.5% of Black, 6.3% of Hispanic, 81.3% of White, and 2.9% of other race and ethnicity). Delaying health care due to feeling nervous about seeing a health care professional was reported by 2300 participants (8.9%). Patient-clinician communication mediated the association between PDHS and delayed care. Mediation proportions decreased with age across all racial and ethnic groups, with the highest proportions observed among participants aged 18 to 44 years (Black participants, 19.5% [95% CI, 14.9%-24.1%]; Hispanic participants, 20.3% [95% CI, 15.6%-25.1%]; White participants, 19.0% [95% CI, 14.7%-23.2%]; participants of other race and ethnicity, 18.3% [95% CI, 13.2%-23.5%]). Within each age group, the highest mediation proportions were observed among Hispanic participants, followed by Black and White participants, and participants of other race and ethnicity.<\/jats:p><\/jats:sec><jats:sec id=\"ab-zoi250004-10\"><jats:title>Conclusions and Relevance<\/jats:title><jats:p>These findings suggest that higher PDHS is positively associated with delaying health care due to nervousness about seeing a health care professional. The largest mediation proportion observed was among younger adults and racial and ethnic minority groups. By prioritizing better PCC, health care delays associated with patient apprehension related to perceived discrimination may be reduced.<\/jats:p><\/jats:sec>","DOI":"10.1001\/jamanetworkopen.2025.0046","type":"journal-article","created":{"date-parts":[[2025,3,4]],"date-time":"2025-03-04T16:30:33Z","timestamp":1741105833000},"page":"e250046","source":"Crossref","is-referenced-by-count":24,"title":["Perceived Discrimination in Health Care Settings and Care Delays in Patients With Diabetes and Hypertension"],"prefix":"10.1001","volume":"8","author":[{"given":"Maryam","family":"Jafari Bidgoli","sequence":"first","affiliation":[{"name":"Department of Community Medicine and Population Health, College of Community Health Sciences, The University of Alabama, Tuscaloosa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hui","family":"Wang","sequence":"additional","affiliation":[{"name":"Institute for Rural Health Research, The University of Alabama, Tuscaloosa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Casey","family":"Macander","sequence":"additional","affiliation":[{"name":"Department of Community Medicine and Population Health, College of Community Health Sciences, The University of Alabama, Tuscaloosa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abbey","family":"Gregg","sequence":"additional","affiliation":[{"name":"Department of Community Medicine and Population Health, College of Community Health Sciences, The University of Alabama, Tuscaloosa"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"10","published-online":{"date-parts":[[2025,3,4]]},"reference":[{"issue":"12","key":"zoi250004r1","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2020.29650","article-title":"Patient-reported experiences of discrimination in the US health care system.","volume":"3","author":"Nong","year":"2020","journal-title":"JAMA Netw Open"},{"issue":"4","key":"zoi250004r2","doi-asserted-by":"publisher","first-page":"531","DOI":"10.1037\/a0016059","article-title":"Perceived discrimination and health: a meta-analytic review.","volume":"135","author":"Pascoe","year":"2009","journal-title":"Psychol Bull"},{"issue":"11","key":"zoi250004r3","doi-asserted-by":"publisher","first-page":"1172","DOI":"10.1007\/s11606-010-1424-8","article-title":"Adherence to cardiovascular disease medications: does patient-provider race\/ethnicity and language concordance matter?","volume":"25","author":"Traylor","year":"2010","journal-title":"J Gen Intern Med"},{"issue":"6","key":"zoi250004r4","doi-asserted-by":"publisher","first-page":"2093","DOI":"10.1111\/j.1475-6773.2009.01017.x","article-title":"Mistrust of health care organizations is associated with underutilization of health services.","volume":"44","author":"LaVeist","year":"2009","journal-title":"Health Serv Res"},{"issue":"3","key":"zoi250004r5","doi-asserted-by":"publisher","first-page":"321","DOI":"10.1016\/j.amepre.2019.04.014","article-title":"Skin tone matters: racial microaggressions and delayed prenatal care.","volume":"57","author":"Slaughter-Acey","year":"2019","journal-title":"Am J Prev Med"},{"issue":"7","key":"zoi250004r6","doi-asserted-by":"publisher","first-page":"578","DOI":"10.1007\/s11606-005-0104-6","article-title":"Perceived discrimination and reported delay of pharmacy prescriptions and medical tests.","volume":"20","author":"Van Houtven","year":"2005","journal-title":"J Gen Intern Med"},{"issue":"6","key":"zoi250004r7","doi-asserted-by":"publisher","first-page":"553","DOI":"10.1111\/j.1525-1497.2006.00413.x","article-title":"Perceived discrimination and use of preventive health services.","volume":"21","author":"Trivedi","year":"2006","journal-title":"J Gen Intern Med"},{"issue":"3","key":"zoi250004r8","first-page":"330","article-title":"The association between perceived provider discrimination, healthcare utilization and health status in racial and ethnic minorities.","volume":"19","author":"Lee","year":"2009","journal-title":"Ethn Dis"},{"issue":"4","key":"zoi250004r9","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0215976","article-title":"Perceived discrimination in medical settings and perceived quality of care: a population-based study in Chicago.","volume":"14","author":"Benjamins","year":"2019","journal-title":"PLoS One"},{"issue":"9","key":"zoi250004r10","first-page":"721","article-title":"R-E-S-P-E-C-T: patient reports of disrespect in the health care setting and its impact on care.","volume":"53","author":"Blanchard","year":"2004","journal-title":"J Fam Pract"},{"issue":"3","key":"zoi250004r11","doi-asserted-by":"publisher","first-page":"894","DOI":"10.1353\/hpu.0.0063","article-title":"The association between perceived discrimination and underutilization of needed medical and mental health care in a multi-ethnic community sample.","volume":"19","author":"Burgess","year":"2008","journal-title":"J Health Care Poor Underserved"},{"issue":"3","key":"zoi250004r12","doi-asserted-by":"publisher","first-page":"389","DOI":"10.1007\/s11606-006-0057-4","article-title":"Perceived discrimination and adherence to medical care in a racially integrated community.","volume":"22","author":"Casagrande","year":"2007","journal-title":"J Gen Intern Med"},{"issue":"7","key":"zoi250004r13","doi-asserted-by":"publisher","first-page":"1156","DOI":"10.1007\/s11606-023-08548-y","article-title":"Delays in accessing healthcare across the gender spectrum in the All of Us Research Program.","volume":"39","author":"Finneran","year":"2024","journal-title":"J Gen Intern Med"},{"issue":"5","key":"zoi250004r14","doi-asserted-by":"publisher","first-page":"1020","DOI":"10.2105\/AJPH.2011.300620","article-title":"Discrimination and the stress response: psychological and physiological consequences of anticipating prejudice in interethnic interactions.","volume":"102","author":"Sawyer","year":"2012","journal-title":"Am J Public Health"},{"issue":"7","key":"zoi250004r15","doi-asserted-by":"publisher","first-page":"626","DOI":"10.1097\/MLR.0b013e318215d93c","article-title":"Impact of perceived discrimination in healthcare on patient-provider communication.","volume":"49","author":"Hausmann","year":"2011","journal-title":"Med Care"},{"issue":"3","key":"zoi250004r16","doi-asserted-by":"publisher","first-page":"295","DOI":"10.1016\/j.pec.2008.11.015","article-title":"How does communication heal? Pathways linking clinician-patient communication to health outcomes.","volume":"74","author":"Street","year":"2009","journal-title":"Patient Educ Couns"},{"issue":"6","key":"zoi250004r17","doi-asserted-by":"publisher","first-page":"595","DOI":"10.1370\/afm.142","article-title":"Effect on health-related outcomes of interventions to alter the interaction between patients and practitioners: a systematic review of trials.","volume":"2","author":"Griffin","year":"2004","journal-title":"Ann Fam Med"},{"issue":"5","key":"zoi250004r18","doi-asserted-by":"publisher","first-page":"791","DOI":"10.1016\/S0277-9536(02)00449-5","article-title":"Interacting with cancer patients: the significance of physicians\u2019 communication behavior.","volume":"57","author":"Arora","year":"2003","journal-title":"Soc Sci Med"},{"issue":"6","key":"zoi250004r19","doi-asserted-by":"publisher","first-page":"1334","DOI":"10.1007\/s10903-019-00867-9","article-title":"Factors impacting adherence to diabetes medication among urban, low income Mexican-Americans with diabetes.","volume":"21","author":"Baghikar","year":"2019","journal-title":"J Immigr Minor Health"},{"issue":"5","key":"zoi250004r20","doi-asserted-by":"publisher","first-page":"2093","DOI":"10.1007\/s00520-015-3014-0","article-title":"Association between patient-provider communication and lung cancer stigma.","volume":"24","author":"Shen","year":"2016","journal-title":"Support Care Cancer"},{"issue":"4","key":"zoi250004r21","doi-asserted-by":"publisher","first-page":"888","DOI":"10.1007\/s11606-020-06391-z","article-title":"Perceptions of patient-provider communication across the six largest Asian subgroups in the USA.","volume":"36","author":"Kirby","year":"2021","journal-title":"J Gen Intern Med"},{"issue":"1","key":"zoi250004r22","doi-asserted-by":"publisher","first-page":"70","DOI":"10.1111\/j.1369-7625.2008.00516.x","article-title":"Measuring patients\u2019 perceptions of communication with healthcare providers: do differences in demographic and socioeconomic characteristics matter?","volume":"12","author":"DeVoe","year":"2009","journal-title":"Health Expect"},{"issue":"4","key":"zoi250004r26","doi-asserted-by":"publisher","first-page":"223","DOI":"10.1038\/s41581-019-0244-2","article-title":"The global epidemiology of hypertension.","volume":"16","author":"Mills","year":"2020","journal-title":"Nat Rev Nephrol"},{"issue":"7","key":"zoi250004r27","doi-asserted-by":"publisher","first-page":"509","DOI":"10.1016\/S2213-8587(23)00129-8","article-title":"Disparities in diabetes prevalence and management by race and ethnicity in the USA: defining a path forward.","volume":"11","author":"Hassan","year":"2023","journal-title":"Lancet Diabetes Endocrinol"},{"issue":"1","key":"zoi250004r28","doi-asserted-by":"publisher","first-page":"20","DOI":"10.1007\/s10865-008-9185-0","article-title":"Discrimination and racial disparities in health: evidence and needed research.","volume":"32","author":"Williams","year":"2009","journal-title":"J Behav Med"},{"issue":"7","key":"zoi250004r29","doi-asserted-by":"publisher","first-page":"668","DOI":"10.1056\/NEJMsr1809937","article-title":"The \u201cAll of Us\u201d Research Program.","volume":"381","author":"Denny","year":"2019","journal-title":"N Engl J Med"},{"issue":"12","key":"zoi250004r30","doi-asserted-by":"publisher","first-page":"1495","DOI":"10.1016\/j.ijsu.2014.07.013","article-title":"The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: guidelines for reporting observational studies.","volume":"12","author":"von Elm","year":"2014","journal-title":"Int J Surg"},{"issue":"4","key":"zoi250004r32","first-page":"502","article-title":"Adapting the everyday discrimination scale to medical settings: reliability and validity testing in a sample of African American patients.","volume":"21","author":"Peek","year":"2011","journal-title":"Ethn Dis"},{"issue":"3","key":"zoi250004r33","doi-asserted-by":"publisher","first-page":"335","DOI":"10.1177\/135910539700200305","article-title":"Racial differences in physical and mental health: socio-economic status, stress and discrimination.","volume":"2","author":"Williams","year":"1997","journal-title":"J Health Psychol"},{"issue":"1","key":"zoi250004r34","doi-asserted-by":"publisher","first-page":"113","DOI":"10.1188\/17.CJON.113-115","article-title":"Reducing patient uncertainty: implementation of a shared decision-making process enhances treatment quality and provider communication.","volume":"21","author":"Gustafson","year":"2017","journal-title":"Clin J Oncol Nurs"},{"issue":"3","key":"zoi250004r35","doi-asserted-by":"publisher","first-page":"363","DOI":"10.1207\/S15327027HC1603_6","article-title":"Perceptions of health care providers\u2019 communication: relationships between patient-centered communication and satisfaction.","volume":"16","author":"Wanzer","year":"2004","journal-title":"Health Commun"},{"issue":"3","key":"zoi250004r36","doi-asserted-by":"publisher","first-page":"157","DOI":"10.1016\/j.anr.2021.06.001","article-title":"Model setting and interpretation of results in research using structural equation modeling: a checklist with guiding questions for reporting.","volume":"15","author":"Kang","year":"2021","journal-title":"Asian Nurs Res (Korean Soc Nurs Sci)"},{"issue":"1","key":"zoi250004r37","doi-asserted-by":"publisher","first-page":"4","DOI":"10.1080\/03637751.2017.1352100","article-title":"Partial, conditional, and moderated moderated mediation: quantification, inference, and interpretation.","volume":"85","author":"Hayes","year":"2018","journal-title":"Commun Monogr"},{"issue":"3","key":"zoi250004r39","doi-asserted-by":"publisher","first-page":"421","DOI":"10.1177\/1359105304042351","article-title":"Psychosocial factors in medical and psychological treatment avoidance: the role of the doctor-patient relationship.","volume":"9","author":"Moore","year":"2004","journal-title":"J Health Psychol"},{"key":"zoi250004r40","doi-asserted-by":"publisher","first-page":"1374","DOI":"10.1111\/1475-6773.13222","article-title":"Understanding how discrimination can affect health.","volume":"54","author":"Williams","year":"2019","journal-title":"Health Serv Res"},{"key":"zoi250004r41","doi-asserted-by":"publisher","DOI":"10.1016\/j.jsat.2021.108551","article-title":"Experiences of racial discrimination in the medical setting and associations with medical mistrust and expectations of care among Black patients seeking addiction treatment.","volume":"133","author":"Hall","year":"2022","journal-title":"J Subst Abuse Treat"},{"issue":"1","key":"zoi250004r42","doi-asserted-by":"publisher","first-page":"251","DOI":"10.1353\/hpu.0.0265","article-title":"Perceived racial discrimination in clinical encounters among African American hypertensive patients.","volume":"21","author":"Greer","year":"2010","journal-title":"J Health Care Poor Underserved"},{"key":"zoi250004r43","doi-asserted-by":"publisher","DOI":"10.1155\/2011\/137492","article-title":"Age-related differences in doctor-patient interaction and patient satisfaction.","volume":"2011","author":"Peck","year":"2011","journal-title":"Curr Gerontol Geriatr Res"},{"issue":"3","key":"zoi250004r44","doi-asserted-by":"publisher","first-page":"212","DOI":"10.2307\/2136517","article-title":"Practitioner or patient\u2013who\u2019s in charge?","volume":"22","author":"Haug","year":"1981","journal-title":"J Health Soc Behav"},{"issue":"1","key":"zoi250004r45","doi-asserted-by":"publisher","first-page":"70","DOI":"10.1111\/j.1369-7625.2008.00516.x","article-title":"Measuring patients\u2019 perceptions of communication","volume":"12","author":"DeVoe","year":"2009","journal-title":"Health Expect"},{"issue":"9","key":"zoi250004r46","doi-asserted-by":"publisher","first-page":"1279","DOI":"10.1016\/0277-9536(94)90191-0","article-title":"Older patient satisfaction with communication during an initial medical encounter.","volume":"38","author":"Greene","year":"1994","journal-title":"Soc Sci Med"},{"issue":"1","key":"zoi250004r48","doi-asserted-by":"publisher","first-page":"4","DOI":"10.1370\/afm.2632","article-title":"Discrimination and Medical Mistrust in a Racially and Ethnically Diverse Sample of California Adults.","volume":"19","author":"Bazargan","year":"2021","journal-title":"Ann Fam Med"},{"key":"zoi250004r49","doi-asserted-by":"publisher","first-page":"615","DOI":"10.1016\/j.pmedr.2015.07.006","article-title":"Perceived discrimination in U.S. healthcare: Charting the effects of key social characteristics within and across racial groups.","volume":"2","author":"Abramson","year":"2015","journal-title":"Prev Med Rep"},{"issue":"1","key":"zoi250004r51","doi-asserted-by":"publisher","first-page":"56","DOI":"10.35680\/2372-0247.1009","article-title":"Improving the patient experience through provider communication skills building.","volume":"1","author":"Kennedy","year":"2014","journal-title":"Patient Exp J"},{"issue":"6","key":"zoi250004r52","doi-asserted-by":"publisher","first-page":"402","DOI":"10.1111\/wvn.12176","article-title":"How effective is cultural competence training of healthcare providers on improving patient satisfaction of minority groups? a systematic review of literature.","volume":"13","author":"Govere","year":"2016","journal-title":"Worldviews Evid Based Nurs"},{"issue":"1","key":"zoi250004r53","doi-asserted-by":"publisher","first-page":"99","DOI":"10.1186\/1472-6963-14-99","article-title":"Interventions to improve cultural competency in healthcare: a systematic review of reviews.","volume":"14","author":"Truong","year":"2014","journal-title":"BMC Health Serv Res"},{"issue":"1","key":"zoi250004r54","doi-asserted-by":"publisher","first-page":"232","DOI":"10.1186\/s12913-018-3001-5","article-title":"Health workforce cultural competency interventions: a systematic scoping review.","volume":"18","author":"Jongen","year":"2018","journal-title":"BMC Health Serv Res"},{"key":"zoi250004r23","volume-title":"Contemporary Perspectives on Ageism","author":"Wyman","year":"2018"},{"key":"zoi250004r25","volume-title":"The Surgeon General\u2019s Call to Action to Control Hypertension","author":"US Department of Health and Human Services","year":"2020"},{"key":"zoi250004r47","volume-title":"Health Communication Research: A Guide to Developments and Directions","author":"Cline","year":"1998"},{"key":"zoi250004r24","unstructured":"Doty MM, Horstman C, Shah A, Ayo-Vaughan M, Zephyrin LC. How discrimination in health care affects older Americans, and what health systems and providers can do. The Commonwealth Fund. Published April 21, 2022. Accessed December 1, 2024. https:\/\/www.commonwealthfund.org\/publications\/issue-briefs\/2022\/apr\/how-discrimination-in-health-care-affects-older-americans"},{"key":"zoi250004r31","unstructured":"Survey explorer. All of Us Research Hub. Accessed November 22, 2024. https:\/\/www.researchallofus.org\/data-tools\/survey-explorer\/"},{"key":"zoi250004r38","unstructured":"All of Us Researcher Workbench. Accessed January 29, 2025. https:\/\/www.researchallofus.org\/data-tools\/workbench\/"},{"key":"zoi250004r50","unstructured":"Advisory Committee on Minority Health. Reflecting America\u2019s population: diversifying a competent health care workforce for the 21st century. US Department of Health and Human Services. Published September 2011. Accessed December 1, 2024. https:\/\/cg-d102dd1b-a880-440b-9eae-e2445148aee9.s3.us-gov-west-1.amazonaws.com\/s3fs-public\/documents\/FinalACMHWorkforceReport.pdf"}],"container-title":["JAMA Network Open"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/jamanetwork.com\/journals\/jamanetworkopen\/articlepdf\/2830837\/jafari_bidgoli_2025_oi_250004_1740155879.29434.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,4]],"date-time":"2025-03-04T16:30:37Z","timestamp":1741105837000},"score":1,"resource":{"primary":{"URL":"https:\/\/jamanetwork.com\/journals\/jamanetworkopen\/fullarticle\/2830837"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3,4]]},"references-count":54,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2025,3,3]]}},"URL":"https:\/\/doi.org\/10.1001\/jamanetworkopen.2025.0046","relation":{},"ISSN":["2574-3805"],"issn-type":[{"value":"2574-3805","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,3,4]]}}}