{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,30]],"date-time":"2026-05-30T01:27:52Z","timestamp":1780104472002,"version":"3.54.0"},"reference-count":29,"publisher":"American Medical Association (AMA)","issue":"9","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JAMA Netw Open"],"abstract":"<jats:sec id=\"ab-zoi250903-4\"><jats:title>Importance<\/jats:title><jats:p>Uterine fibroid embolization (UFE) is a minimally invasive alternative to surgery. Understanding utilization patterns and disparities in access is important to ensure that patients can explore all treatment options.<\/jats:p><\/jats:sec><jats:sec id=\"ab-zoi250903-5\"><jats:title>Objective<\/jats:title><jats:p>To examine trends in the use of UFE vs hysterectomy and myomectomy for uterine fibroid management, with an emphasis on sociodemographic and institutional disparities.<\/jats:p><\/jats:sec><jats:sec id=\"ab-zoi250903-6\"><jats:title>Design, Setting, and Participants<\/jats:title><jats:p>This cross-sectional analysis used data from the 2016 to 2022 National Inpatient Sample obtained from the Healthcare Cost and Utilization Project, a population-based, multicenter inpatient dataset representing hospitals across the US. Adult patients with a diagnosis of uterine fibroids who underwent hysterectomy, myomectomy, or UFE were identified using <jats:italic>International Statistical Classification of Diseases, Tenth Revision, Clinical Modification<\/jats:italic> codes. Analysis was conducted in April 2025.<\/jats:p><\/jats:sec><jats:sec id=\"ab-zoi250903-7\"><jats:title>Exposure<\/jats:title><jats:p>Patient age, race, ethnicity, insurance, income quartile, rurality, year of procedure, and hospital characteristics.<\/jats:p><\/jats:sec><jats:sec id=\"ab-zoi250903-8\"><jats:title>Main Outcomes and Measures<\/jats:title><jats:p>The primary outcome was undergoing UFE, modeled using multivariable logistic regression, with hysterectomy, myomectomy, or surgery overall as reference groups. The covariate reference categories were age younger than 30 years, White race, private insurance, 76th to 100th income percentile, central metropolitan residence, the year 2016, small hospitals, rural hospitals, and hospitals in the Pacific division. Results were reported as adjusted odds ratios (aORs) with 95% CIs.<\/jats:p><\/jats:sec><jats:sec id=\"ab-zoi250903-9\"><jats:title>Results<\/jats:title><jats:p>The sample encompassed 271\u202f885 encounters, including 199\u202f625 hysterectomies (73.4%), 62\u202f675 myomectomies (23.1%), and 9585 UFEs (3.5%). The median (IQR) patient age was 47 (43-52) years for those undergoing hysterectomy, 45 (40-49) years for those undergoing UFE, and 37 (33-41) years for those undergoing myomectomy. With regard to race and ethnicity, 105\u202f780 patients (38.9%) were African American, 16\u202f175 (5.9%) were Asian or Pacific Islander, 48\u202f810 (18.0%) were Hispanic, 1050 (0.4%) were Native American, 86\u202f425 were White (31.8%), and 13\u202f645 (5.0%) were other races. Increasing age was associated with lower odds of undergoing UFE vs hysterectomy, and higher odds of undergoing UFE vs myomectomy. African American patients were more likely to undergo UFE than hysterectomy (aOR, 1.64; 95% CI, 1.44-1.87), but less likely to undergo UFE than myomectomy (aOR, 0.84; 95% CI, 0.73-0.97). Hispanic patients were less likely to undergo UFE than both surgical procedures (aOR, 0.83; 95% CI, 0.71-0.97). Patients with Medicaid (aOR, 1.58; 95% CI, 1.41-1.77), self-pay (aOR, 1.97; 95% CI, 1.60-2.42), and no-charge (aOR, 1.97; 95% CI, 1.24-3.12) coverage had higher odds of undergoing UFE vs both surgical procedures. Among Medicare patients, UFE was more likely than myomectomy among those aged 30 to 49 years, but less likely among those aged 50 years and older. Those in the lowest income quartile (0-25th percentile) had greater odds of undergoing UFE vs myomectomy (aOR, 1.22; 95% CI, 1.04-1.43). Rural patients were less likely to undergo UFE than hysterectomy (aOR, 0.53; 95% CI, 0.34-0.83), whereas urban hospitals were more likely to perform UFE than both surgical procedures (aOR, 7.13; 95% CI, 3.43-14.80).<\/jats:p><\/jats:sec><jats:sec id=\"ab-zoi250903-10\"><jats:title>Conclusions and Relevance<\/jats:title><jats:p>In this cross-sectional study, UFE was underutilized with significant disparities across socioeconomic factors. Further efforts are needed to equitably expand access to UFE across the country.<\/jats:p><\/jats:sec>","DOI":"10.1001\/jamanetworkopen.2025.32100","type":"journal-article","created":{"date-parts":[[2025,9,16]],"date-time":"2025-09-16T15:00:27Z","timestamp":1758034827000},"page":"e2532100","source":"Crossref","is-referenced-by-count":3,"title":["Disparities in Utilization of Uterine Fibroid Embolization"],"prefix":"10.1001","volume":"8","author":[{"given":"Tarig S.","family":"Elhakim","sequence":"first","affiliation":[{"name":"Perelman School of Medicine at the University of Pennsylvania, Philadelphia"},{"name":"Department of Radiology, Massachusetts General Hospital, Boston"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara","family":"Smolinski-Zhao","sequence":"additional","affiliation":[{"name":"Department of Radiology, Massachusetts General Hospital, Boston"},{"name":"Department of Radiology, Harvard Medical School, Boston, Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dominie","family":"Miyasato","sequence":"additional","affiliation":[{"name":"Department of Radiology, Harvard Medical School, Boston, Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vladlena","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Radiology, Harvard Medical School, Boston, Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arian","family":"Mansur","sequence":"additional","affiliation":[{"name":"Department of Radiology, Harvard Medical School, Boston, Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Puello","sequence":"additional","affiliation":[{"name":"School of Medicine, Universidad Del Norte, Atlantico, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nathaniel","family":"Mercaldo","sequence":"additional","affiliation":[{"name":"Department of Radiology, Massachusetts General Hospital, Boston"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna Sophia","family":"McKenney","sequence":"additional","affiliation":[{"name":"Department of Radiology, New York\u2013Presbyterian Hospital\/Weill Cornell Medical Center, New York, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sanjeeva P.","family":"Kalva","sequence":"additional","affiliation":[{"name":"Department of Radiology, Massachusetts General Hospital, Boston"},{"name":"Department of Radiology, Harvard Medical School, Boston, Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Dezube","sequence":"additional","affiliation":[{"name":"Department of Radiology, Massachusetts General Hospital, Boston"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dania","family":"Daye","sequence":"additional","affiliation":[{"name":"Department of Radiology, Massachusetts General Hospital, Boston"},{"name":"Department of Radiology, Harvard Medical School, Boston, Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"10","published-online":{"date-parts":[[2025,9,16]]},"reference":[{"issue":"1","key":"zoi250903r1","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1002\/ijgo.13102","article-title":"Epidemiology and management of uterine fibroids.","volume":"149","author":"Giuliani","year":"2020","journal-title":"Int J Gynaecol Obstet"},{"issue":"6","key":"zoi250903r2","doi-asserted-by":"publisher","first-page":"473","DOI":"10.1055\/s-0037-1607264","article-title":"Uterine fibroids: burden and unmet medical need.","volume":"35","author":"Al-Hendy","year":"2017","journal-title":"Semin Reprod Med"},{"issue":"1","key":"zoi250903r4","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1097\/AOG.0000000000001160","article-title":"Association between patient characteristics and treatment procedure among patients with uterine 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Mobil"},{"issue":"10","key":"zoi250903r19","doi-asserted-by":"publisher","first-page":"1237","DOI":"10.1016\/j.jacr.2020.03.018","article-title":"Invasive procedural treatments for symptomatic uterine fibroids: a cost analysis.","volume":"17","author":"Cronan","year":"2020","journal-title":"J Am Coll Radiol"},{"issue":"6S","key":"zoi250903r20","doi-asserted-by":"publisher","first-page":"S203","DOI":"10.1016\/j.jacr.2024.02.022","article-title":"ACR Appropriateness Criteria\u00ae management of uterine fibroids: 2023 update.","volume":"21","author":"Makary","year":"2024","journal-title":"J Am Coll Radiol"},{"issue":"13","key":"zoi250903r21","doi-asserted-by":"publisher","first-page":"3632","DOI":"10.3390\/jcm13133632","article-title":"Evolving referral patterns and management following implementation of a multidisciplinary fibroid center: a retrospective cohort study.","volume":"13","author":"Musselman","year":"2024","journal-title":"J Clin 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Management of symptomatic uterine leiomyomas: practice bulletin 228. June 2021. Accessed October 14, 2024. https:\/\/www.acog.org\/clinical\/clinical-guidance\/practice-bulletin\/articles\/2021\/06\/management-of-symptomatic-uterine-leiomyomas"},{"key":"zoi250903r9","unstructured":"Gliklich? RE, Leavy? MB, Velentgas? P, . Identification of future research needs in the comparative management of uterine fibroid disease: a report on the priority-setting process, preliminary data analysis, and research plan. Agency for Healthcare Research and Quality. March 10, 2011. Accessed August 8, 2025. https:\/\/effectivehealthcare.ahrq.gov\/products\/uterine-fibroids-2010\/research"},{"key":"zoi250903r11","unstructured":"Healthcare Cost and Utilization Project. Overview of the National (Nationwide) Inpatient Sample (NIS). Accessed October 16, 2024. https:\/\/hcup-us.ahrq.gov\/nisoverview.jsp"},{"key":"zoi250903r12","unstructured":"Healthcare Cost and Utilization Project. 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