{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T03:48:45Z","timestamp":1790135325059,"version":"4.0.1"},"reference-count":34,"publisher":"American Medical Association (AMA)","issue":"10","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JAMA Netw Open"],"abstract":"<jats:sec id=\"ab-zoi251007-4\"><jats:title>Importance<\/jats:title><jats:p>A growing number of older adults live in unaffordable and unstable housing; however, whether programs designed to counter housing insecurity contribute to earlier-stage cancer diagnosis remains largely unknown.<\/jats:p><\/jats:sec><jats:sec id=\"ab-zoi251007-5\"><jats:title>Objective<\/jats:title><jats:p>To examine the association between the receipt of federal housing assistance, which limits household spending on rent and utilities, and cancer stage at diagnosis among older adults in the US.<\/jats:p><\/jats:sec><jats:sec id=\"ab-zoi251007-6\"><jats:title>Design, Setting, and Participants<\/jats:title><jats:p>This comparative cohort study used the Surveillance, Epidemiology, and End Results cancer registry program and Medicare database linked with data from the US Department of Housing and Urban Development (HUD). Participants were individuals aged 66 to 95 years who received new diagnoses of breast cancer, colorectal cancer, non\u2013small cell lung cancer (NSCLC), or prostate cancer between 2007 and 2019. Data were acquired in 2023, and the data analysis was performed from June 2023 through March 2025.<\/jats:p><\/jats:sec><jats:sec id=\"ab-zoi251007-7\"><jats:title>Exposure<\/jats:title><jats:p>Receipt of federal housing assistance.<\/jats:p><\/jats:sec><jats:sec id=\"ab-zoi251007-8\"><jats:title>Main Outcomes and Measures<\/jats:title><jats:p>The primary outcome was stage at cancer diagnosis, defined as in situ (for breast cancer only), localized, regional, or distant. Odds ratios (ORs) for the association between having HUD assistance at diagnosis and cancer stage at diagnosis were estimated using multinomial (nonproportional odds) regression. Individuals with HUD assistance were propensity score matched to individuals without housing assistance.<\/jats:p><\/jats:sec><jats:sec id=\"ab-zoi251007-9\"><jats:title>Results<\/jats:title><jats:p>A total of 52\u202f532 individuals (mean [SD] age at diagnosis, 76.3 [6.8] years; 33\u202f608 women [64.0%]) with housing assistance at diagnosis were included: 16\u202f064 had breast cancer, 10\u202f807 had colorectal cancer, 17\u202f156 had NCSLC, and 8505 had prostate cancer; 38\u202f183 (72.7%) were enrolled in Medicaid, and 38\u202f539 (73.4%) had Part D low-income cost sharing. Compared with matched controls, fewer individuals with housing assistance received a diagnosis of distant breast cancer (1071 patients [6.7%] vs 3485 patients [7.2%]; adjusted OR [aOR], 0.85; 95% CI, 0.82- 0.90), distant colorectal cancer (2398 patients [22.2%] vs 7562 patients [23.3%]; aOR, 0.90; 95% CI, 0.83-0.98), and distant NSCLC (8810 patients [51.4%] vs 27\u202f901 patients [54.2%]; aOR, 0.83; 95% CI, 0.79-0.86) compared with localized cancers. Housing assistance was not significantly associated with stage at diagnosis for individuals with prostate cancer. The association between housing assistance and stage at cancer diagnosis varied across the different types of housing assistance, including the Housing Choice voucher program, multifamily housing, and public housing.<\/jats:p><\/jats:sec><jats:sec id=\"ab-zoi251007-10\"><jats:title>Conclusions and Relevance<\/jats:title><jats:p>The findings of this cohort study of older adults with cancer suggest that federal housing assistance was associated with earlier-stage diagnosis of breast cancer, colorectal cancer, and NSCLC, highlighting its potential role in mitigating the adverse associations of housing insecurity with cancer outcomes.<\/jats:p><\/jats:sec>","DOI":"10.1001\/jamanetworkopen.2025.36281","type":"journal-article","created":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T15:00:51Z","timestamp":1759935651000},"page":"e2536281","source":"Crossref","is-referenced-by-count":3,"title":["Federal Housing Assistance and Stage at Cancer Diagnosis Among Older Adults in the US"],"prefix":"10.1001","volume":"8","author":[{"given":"Craig Evan","family":"Pollack","sequence":"first","affiliation":[{"name":"Department of Health Policy and Management, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland"},{"name":"Johns Hopkins School of Nursing, Baltimore, Maryland"},{"name":"Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland"},{"name":"Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins Medicine, Baltimore, Maryland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amanda L.","family":"Blackford","sequence":"additional","affiliation":[{"name":"Division of Quantitative Sciences, Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Taylor K.","family":"Craig","sequence":"additional","affiliation":[{"name":"Biostatistics, Epidemiology and Data Management Core, Johns Hopkins University School of Medicine, Baltimore, Maryland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qinjin","family":"Fan","sequence":"additional","affiliation":[{"name":"Surveillance, Prevention, & Health Services Research (SPHeRe), American Cancer Society, Atlanta, Georgia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S. M. Qasim","family":"Hussaini","sequence":"additional","affiliation":[{"name":"Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins Medicine, Baltimore, Maryland"},{"name":"O\u2019Neal Comprehensive Cancer Center, Division of Hematology & Oncology, Department of Medicine, University of Alabama at Birmingham, Birmingham"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katherine L.","family":"Chen","sequence":"additional","affiliation":[{"name":"Division of General Internal Medicine & Health Services Research, Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Polsky","sequence":"additional","affiliation":[{"name":"Department of Health Policy and Management, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland"},{"name":"Carey Business School, Johns Hopkins University, Baltimore, Maryland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Margaret","family":"Katana Ogongo","sequence":"additional","affiliation":[{"name":"Surveillance, Prevention, & Health Services Research (SPHeRe), American Cancer Society, Atlanta, Georgia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joan L.","family":"Warren","sequence":"additional","affiliation":[{"name":"Surveillance, Prevention, & Health Services Research (SPHeRe), American Cancer Society, Atlanta, Georgia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cary P.","family":"Gross","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut"},{"name":"Yale Cancer Outcomes, Public Policy, and Effectiveness Research Center, New Haven, Connecticut"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K. Robin","family":"Yabroff","sequence":"additional","affiliation":[{"name":"Surveillance, Prevention, & Health Services Research (SPHeRe), American Cancer Society, Atlanta, Georgia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"10","published-online":{"date-parts":[[2025,10,8]]},"reference":[{"issue":"1","key":"zoi251007r1","doi-asserted-by":"publisher","first-page":"10","DOI":"10.3322\/caac.21871","article-title":"Cancer statistics, 2025.","volume":"75","author":"Siegel","year":"2025","journal-title":"CA Cancer J Clin"},{"issue":"4","key":"zoi251007r2","doi-asserted-by":"publisher","first-page":"308","DOI":"10.3322\/caac.70011","article-title":"Cancer treatment and survivorship statistics, 2025.","volume":"75","author":"Wagle","year":"2025","journal-title":"CA Cancer J Clin"},{"issue":"7","key":"zoi251007r3","doi-asserted-by":"publisher","first-page":"1304","DOI":"10.1158\/1055-9965.EPI-19-1534","article-title":"Medical care costs associated with cancer survivorship in the United States.","volume":"29","author":"Mariotto","year":"2020","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"issue":"8","key":"zoi251007r4","doi-asserted-by":"publisher","first-page":"863","DOI":"10.1093\/jnci\/djz123","article-title":"Trends in mortality due to cancer in the United States by age and county-level income, 1999-2015.","volume":"111","author":"Withrow","year":"2019","journal-title":"J Natl Cancer Inst"},{"issue":"5","key":"zoi251007r6","doi-asserted-by":"publisher","first-page":"678","DOI":"10.1200\/OP.23.00426","article-title":"Association of historical housing discrimination and colon cancer treatment and outcomes in the United States.","volume":"20","author":"Hussaini","year":"2024","journal-title":"JCO Oncol Pract"},{"issue":"6","key":"zoi251007r8","doi-asserted-by":"publisher","first-page":"1212","DOI":"10.1007\/s11524-023-00799-8","article-title":"The affordable rental housing crisis and population health equity: a multidimensional and multilevel framework.","volume":"100","author":"Keene","year":"2023","journal-title":"J Urban Health"},{"issue":"21","key":"zoi251007r9","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2116169119","article-title":"Estimating eviction prevalence across the United States.","volume":"119","author":"Gromis","year":"2022","journal-title":"Proc Natl Acad Sci U S A"},{"key":"zoi251007r11","doi-asserted-by":"publisher","first-page":"767","DOI":"10.1038\/s41568-021-00395-5","article-title":"Stress and cancer: mechanisms, significance and future directions.","volume":"21","author":"Eckerling","year":"2021","journal-title":"Nat Rev Cancer"},{"issue":"12","key":"zoi251007r14","doi-asserted-by":"publisher","first-page":"1584","DOI":"10.1093\/jnci\/djac136","article-title":"Housing insecurity among patients with cancer.","volume":"114","author":"Fan","year":"2022","journal-title":"J Natl Cancer Inst"},{"issue":"12","key":"zoi251007r15","doi-asserted-by":"publisher","first-page":"1601","DOI":"10.1093\/jnci\/djac173","article-title":"Housing and cancer care and outcomes: a systematic review.","volume":"114","author":"Fan","year":"2022","journal-title":"J Natl Cancer Inst"},{"issue":"8","key":"zoi251007r17","doi-asserted-by":"publisher","first-page":"1270","DOI":"10.1093\/jnci\/djae082","article-title":"Housing assistance among patients with cancer: SEER-Medicare US Department of Housing and Urban Development data linkage.","volume":"116","author":"Pollack","year":"2024","journal-title":"J Natl Cancer Inst"},{"issue":"9","key":"zoi251007r19","doi-asserted-by":"publisher","first-page":"1","DOI":"10.18637\/jss.v111.i09","article-title":"How to interpret statistical models using marginaleffects for R and Python.","volume":"111","author":"Arel-Bundock","year":"2024","journal-title":"J Stat Softw"},{"issue":"5","key":"zoi251007r21","doi-asserted-by":"publisher","first-page":"773","DOI":"10.1037\/a0036515","article-title":"Examining moderation analyses in propensity score methods: application to depression and substance use.","volume":"82","author":"Green","year":"2014","journal-title":"J Consult Clin Psychol"},{"key":"zoi251007r22","doi-asserted-by":"publisher","first-page":"92","DOI":"10.1016\/j.jclinepi.2023.09.014","article-title":"The use of the E-value for sensitivity analysis.","volume":"163","author":"Chung","year":"2023","journal-title":"J Clin Epidemiol"},{"issue":"12","key":"zoi251007r25","doi-asserted-by":"publisher","first-page":"2714","DOI":"10.1007\/s11606-019-05037-z","article-title":"The relationship between federal housing assistance and uptake of cancer screening among low-income adults.","volume":"34","author":"Wong","year":"2019","journal-title":"J Gen Intern Med"},{"issue":"10","key":"zoi251007r26","doi-asserted-by":"publisher","first-page":"3188","DOI":"10.1111\/jgs.19069","article-title":"\u201cI make myself get busy\u201d: resilience and social connection among low-income older adults living in subsidized housing.","volume":"72","author":"Blinka","year":"2024","journal-title":"J Am Geriatr Soc"},{"issue":"5","key":"zoi251007r27","doi-asserted-by":"publisher","first-page":"990","DOI":"10.1007\/s11524-024-00905-4","article-title":"Assessing the burden of electrical, elevator, heat, hot water, and water service interruptions in New York City public housing.","volume":"101","author":"Flores","year":"2024","journal-title":"J Urban Health"},{"issue":"4","key":"zoi251007r28","doi-asserted-by":"publisher","first-page":"571","DOI":"10.2105\/AJPH.2016.303649","article-title":"Housing assistance programs and adult health in the United States.","volume":"107","author":"Fenelon","year":"2017","journal-title":"Am J Public Health"},{"issue":"6","key":"zoi251007r30","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2017-2742","article-title":"Housing assistance and child health: a systematic review.","volume":"141","author":"Slopen","year":"2018","journal-title":"Pediatrics"},{"issue":"7","key":"zoi251007r31","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2022.22385","article-title":"Association between rental assistance programs and hemoglobin A1c levels among US adults.","volume":"5","author":"Fenelon","year":"2022","journal-title":"JAMA Netw Open"},{"key":"zoi251007r32","doi-asserted-by":"publisher","DOI":"10.1016\/j.ypmed.2023.107453","article-title":"Rental assistance improves food security and nutrition: an analysis of National Survey Data.","volume":"169","author":"Denary","year":"2023","journal-title":"Prev Med"},{"issue":"9","key":"zoi251007r33","doi-asserted-by":"publisher","first-page":"1625","DOI":"10.1007\/s11606-024-08673-2","article-title":"Association between rental assistance programs and undiagnosed diabetes among U.S.","volume":"39","author":"Gonzalez-Lopez","year":"2024","journal-title":"J Gen Intern Med"},{"issue":"22","key":"zoi251007r34","doi-asserted-by":"publisher","first-page":"5518","DOI":"10.1002\/cncr.27577","article-title":"Primary care providers\u2019 perspectives on discontinuing prostate cancer screening.","volume":"118","author":"Pollack","year":"2012","journal-title":"Cancer"},{"key":"zoi251007r5","unstructured":"Taylor? LA. Housing and health: an overview of the literature. June 7, 2018. Accessed August 19, 2025. https:\/\/www.healthaffairs.org\/content\/briefs\/housing-and-health-overview-literature"},{"key":"zoi251007r7","unstructured":"Rothstein? R. The color of law: a forgotten history of how our government segregated America. Economic Policy Institute. Liveright; 2017. Accessed December 12, 2024. https:\/\/www.epi.org\/publication\/the-color-of-law-a-forgotten-history-of-how-our-government-segregated-america\/"},{"key":"zoi251007r10","unstructured":"Aurand? A, Emmanel? D, Threet? D, Yentel? D. The gap: a shortage of affordable homes. National Low Income Housing Coalition. 2024. Accessed August 19, 2025. https:\/\/nlihc.org\/sites\/default\/files\/gap\/2024\/Gap-Report_2024.pdf"},{"key":"zoi251007r12","unstructured":"Zhu? L, Zinn? A.  America\u2019s housing market is failing older adults. Urban Institute. March 12, 2025. Accessed August 28, 2025. https:\/\/www.urban.org\/urban-wire\/americas-housing-market-failing-older-adults"},{"key":"zoi251007r13","unstructured":"U.S. Department of Housing and Urband Development: Office of Police Development and Research. Assisted housing: national and local. Accessed December 12, 2024. https:\/\/www.huduser.gov\/portal\/datasets\/assthsg.html#2009-2020_query"},{"key":"zoi251007r16","unstructured":"Acosta? S. Lawmakers should prioritize adequate funding for rental assistance for people struggling to afford housing in housing appropriations legislation. Center on Budget and Policy Priorities. June 14, 2023. Accessed December 12, 2024. https:\/\/www.cbpp.org\/blog\/lawmakers-should-prioritize-adequate-funding-for-rental-assistance-for-people-struggling-to"},{"key":"zoi251007r18","unstructured":"R Core Team. R: a language and environment for statistical computing. 2024. Accessed December 19, 2024. https:\/\/www.R-project.org\/"},{"key":"zoi251007r20","unstructured":"Neumann? M. MNLpred: simulated predicted probabilities for multinomial logit models. 2021. Accessed August 19, 2025. https:\/\/r-mirror.zim.uni-due.de\/web\/packages\/MNLpred\/MNLpred.pdf"},{"key":"zoi251007r23","unstructured":"National Cancer Institute. SEER*Explorer Application. 2022. Accessed March 9, 2025. https:\/\/seer.cancer.gov\/statistics-network\/explorer\/application.html?site=1&data_type=1&graph_type=2&compareBy=sex&chk_sex_3=3&chk_sex_2=2&rate_type=2&race=1&age_range=1&hdn_stage=101&advopt_precision=1&advopt_show_ci=on&hdn_view=0&advopt_show_apc=on&advopt_display=2#resultsRegion0"},{"key":"zoi251007r24","unstructured":"Alvarez? T, Steffen? B. Worst case housing needs: 2023 report to Congress. U.S. Department of Housing and Urband Development: Office of Police Development and Research. September 21, 2023. Accessed August 19, 2025. https:\/\/www.huduser.gov\/portal\/publications\/Worst-Case-Housing-Needs-2023.html"},{"key":"zoi251007r29","unstructured":"Center on Budget and Policy Priorities. Federal rental assistance fact sheets. 2025. Accessed August 3, 2025. https:\/\/www.cbpp.org\/research\/housing\/federal-rental-assistance-fact-sheets#US"}],"container-title":["JAMA Network Open"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/jamanetwork.com\/journals\/jamanetworkopen\/articlepdf\/2839762\/pollack_2025_oi_251007_1759324737.07575.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T15:00:59Z","timestamp":1759935659000},"score":1,"resource":{"primary":{"URL":"https:\/\/jamanetwork.com\/journals\/jamanetworkopen\/fullarticle\/2839762"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10,8]]},"references-count":34,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2025,10,1]]}},"URL":"https:\/\/doi.org\/10.1001\/jamanetworkopen.2025.36281","relation":{},"ISSN":["2574-3805"],"issn-type":[{"value":"2574-3805","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,10,8]]}}}