{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T01:35:38Z","timestamp":1793151338206,"version":"4.5.0"},"reference-count":41,"publisher":"American Medical Association (AMA)","issue":"12","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JAMA Netw Open"],"abstract":"<jats:sec id=\"ab-zsc250009-1\">\n                    <jats:title>Importance<\/jats:title>\n                    <jats:p>\n                      Pertussis, or whooping cough, is caused by the\n                      <jats:italic toggle=\"yes\">Bordetella pertussis<\/jats:italic>\n                      bacterium. It induces prolonged cough in all age groups and is a severe, life-threatening disease in young infants.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"ab-zsc250009-2\">\n                    <jats:title>Observations<\/jats:title>\n                    <jats:p>\n                      In an online workshop organized by the International Bordetella Society on November 12, 2024, most participating countries reported very low pertussis incidence during and immediately following the COVID-19 pandemic. Since that time, many countries have seen large outbreaks of pertussis, particularly in adolescents. Before the pandemic, several countries, especially those using acellular pertussis vaccine in infants, reported circulating\n                      <jats:italic toggle=\"yes\">B pertussis<\/jats:italic>\n                      isolates that lacked the acellular vaccine antigen pertactin. However, most recent isolates have been found to express this antigen. A rise in macrolide-resistant\n                      <jats:italic toggle=\"yes\">B pertussis<\/jats:italic>\n                      isolates was also reported by several countries.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"ab-zsc250009-3\">\n                    <jats:title>Conclusions and Relevance<\/jats:title>\n                    <jats:p>The potential for large outbreaks of pertussis highlights the importance of maintaining or increasing vaccine coverage in pregnancy and in infants and children. The data presented herein suggest a need for new pertussis vaccines that protect against both disease and infection and that reduce transmission.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1001\/jamanetworkopen.2025.45963","type":"journal-article","created":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T16:00:28Z","timestamp":1764604828000},"page":"e2545963","source":"Crossref","is-referenced-by-count":39,"title":["Global Incidence of Pertussis After the COVID-19 Pandemic"],"prefix":"10.1001","volume":"8","author":[{"given":"Andrew","family":"Gorringe","sequence":"first","affiliation":[{"name":"UK Health Security Agency, Porton Down, Salisbury, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Breeze","family":"Cavell","sequence":"additional","affiliation":[{"name":"UK Health Security Agency, Porton Down, Salisbury, United 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