{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,20]],"date-time":"2026-06-20T10:16:00Z","timestamp":1781950560712,"version":"3.54.5"},"reference-count":49,"publisher":"American Medical Association (AMA)","issue":"12","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JAMA Netw Open"],"abstract":"<jats:sec id=\"ab-zoi251300-4\">\n                    <jats:title>Importance<\/jats:title>\n                    <jats:p>Pregnant individuals seeking information about the safety of prenatal cannabis use may view budtenders (individuals who work at cannabis retailers) as a trusted source of information. However, the recommendations that budtenders provide to pregnant individuals considering cannabis use are unknown.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"ab-zoi251300-5\">\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To characterize how budtenders respond to questions about the safety of blunt, tobacco, and cannabis use during pregnancy, and to evaluate whether advice varied by indication for use or by whether the retailer provided delivery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"ab-zoi251300-6\">\n                    <jats:title>Design, Setting, and Participants<\/jats:title>\n                    <jats:p>In this cross-sectional study of California cannabis retailers, mystery shoppers posed as pregnant individuals looking for advice about the safety of prenatal substance use. Telephone calls with randomly selected licensed storefront retailers were conducted from February 26, 2024, to January 28, 2025.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"ab-zoi251300-7\">\n                    <jats:title>Exposures<\/jats:title>\n                    <jats:p>Mystery shoppers followed 2 versions of a script (mental health vs no mental health indications for use) with questions about the safety of prenatal blunt, tobacco, and cannabis use.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"ab-zoi251300-8\">\n                    <jats:title>Main Outcomes and Measures<\/jats:title>\n                    <jats:p>The primary outcome was retailers\u2019 responses about the safety of prenatal blunt, tobacco, and cannabis use. Secondary outcomes included product recommendations, opinions on safer vs more harmful modes of prenatal cannabis use, and whether to speak with a physician.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"ab-zoi251300-9\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Of the 505 employees at selected retailers (ie, budtenders), 79.6% (95% CI, 74.8%-83.7%) said prenatal blunt use was unsafe, 79.2% (95% CI, 74.4%-86.4%) said prenatal tobacco use was unsafe, and 40.4% (95% CI, 35.1%-45.9%) said prenatal cannabis use was unsafe. More advised that prenatal cannabis use was safe (20.6%; 95% CI, 16.0%-26.1%) vs blunts (0.8%; 95% CI, 0.2%-2.9%) or tobacco (0.8%; 95% CI, 0.2%-2.9%) or stated that they could not give advice about the safety of prenatal cannabis (19.8%; 95% CI, 15.3%-25.2%) vs tobacco (14.3%; 95% CI, 10.5%-19.2%). Only 5.7% (95% CI, 4.0%-8.1%) mentioned store or product warnings. Budtender recommendations included low- or no-tetrahydrocannabinol cannabis products, harm reduction (eg, use less frequently), and noncannabis strategies (eg, mindfulness). Edibles were most endorsed as safe, while smoking was most endorsed as harmful. Overall, 44.0% (95% CI, 37.3%-50.8%) recommended speaking to a physician before prompting and 46.1% (95% CI, 39.4%-53.0%) after prompting. Responses were generally similar regardless of stated indication for use or delivery service availability.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"ab-zoi251300-10\">\n                    <jats:title>Conclusions and Relevance<\/jats:title>\n                    <jats:p>In this cross-sectional study, most budtenders advised against prenatal blunt and tobacco use. Fewer advised against prenatal cannabis use, highlighting the need for more visible, effective warnings and mandatory budtender education covering risks of prenatal cannabis use.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1001\/jamanetworkopen.2025.48373","type":"journal-article","created":{"date-parts":[[2025,12,10]],"date-time":"2025-12-10T16:00:35Z","timestamp":1765382435000},"page":"e2548373","source":"Crossref","is-referenced-by-count":3,"title":["Cannabis Retailer Advice on Blunt, Tobacco, and Cannabis Use During Pregnancy"],"prefix":"10.1001","volume":"8","author":[{"given":"Kelly C.","family":"Young-Wolff","sequence":"first","affiliation":[{"name":"Division of Research, Kaiser Permanente Northern California, Pleasanton"},{"name":"Department of Psychiatry and Behavioral Sciences, University of California, San Francisco"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monique B.","family":"Does","sequence":"additional","affiliation":[{"name":"Division of Research, Kaiser Permanente Northern California, Pleasanton"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rahel","family":"Negusse","sequence":"additional","affiliation":[{"name":"Division of Research, Kaiser Permanente Northern California, Pleasanton"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shannon N.","family":"Ogden","sequence":"additional","affiliation":[{"name":"Division of Research, Kaiser Permanente Northern California, Pleasanton"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joshua R.","family":"Nugent","sequence":"additional","affiliation":[{"name":"Division of Research, Kaiser Permanente Northern California, Pleasanton"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lynn D.","family":"Silver","sequence":"additional","affiliation":[{"name":"Prevention Policy Group Public Health Institute, Oakland, California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aurash J.","family":"Soroosh","sequence":"additional","affiliation":[{"name":"Prevention Policy Group Public Health Institute, Oakland, California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Torri D.","family":"Metz","sequence":"additional","affiliation":[{"name":"University of Colorado School of Medicine, Aurora"},{"name":"Denver Health and Hospital Authority, Denver, Colorado"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"10","published-online":{"date-parts":[[2025,12,10]]},"reference":[{"issue":"8","key":"zoi251300r1","doi-asserted-by":"publisher","first-page":"1073","DOI":"10.2105\/AJPH.2018.304469","article-title":"Cigar and marijuana blunt use among pregnant and nonpregnant women of reproductive age in the United States, 2006-2016.","volume":"108","author":"Coleman-Cowger","year":"2018","journal-title":"Am J Public Health"},{"key":"zoi251300r2","doi-asserted-by":"publisher","DOI":"10.1016\/j.drugalcdep.2020.108168","article-title":"Trends and correlates of self-reported alcohol and nicotine use among women before and during pregnancy, 2009-2017.","volume":"214","author":"Young-Wolff","year":"2020","journal-title":"Drug Alcohol Depend"},{"issue":"2","key":"zoi251300r3","doi-asserted-by":"publisher","first-page":"167","DOI":"10.1001\/jama.2019.7982","article-title":"Self-reported medical and nonmedical cannabis use among pregnant women in the United States.","volume":"322","author":"Volkow","year":"2019","journal-title":"JAMA"},{"issue":"7","key":"zoi251300r4","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2019.6471","article-title":"Self-reported daily, weekly, and monthly cannabis use among women before and during pregnancy.","volume":"2","author":"Young-Wolff","year":"2019","journal-title":"JAMA Netw Open"},{"issue":"17","key":"zoi251300r6","doi-asserted-by":"publisher","first-page":"1745","DOI":"10.1001\/jama.2021.16328","article-title":"Rates of prenatal cannabis use among pregnant women before and during the COVID-19 pandemic.","volume":"326","author":"Young-Wolff","year":"2021","journal-title":"JAMA"},{"issue":"4","key":"zoi251300r7","doi-asserted-by":"publisher","DOI":"10.1016\/j.amepre.2025.107967","article-title":"Cannabis use among pregnant and nonpregnant women of childbearing age: findings from the 2021-2023 National Survey of Drug Use and Health.","volume":"69","author":"Grigsby","year":"2025","journal-title":"Am J Prev Med"},{"key":"zoi251300r8","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2017.05.050","article-title":"Maternal marijuana use, adverse pregnancy outcomes, and neonatal morbidity.","author":"Metz","year":"2017","journal-title":"Am J Obstet Gynecol"},{"issue":"6","key":"zoi251300r9","doi-asserted-by":"publisher","first-page":"512","DOI":"10.1111\/ppe.12505","article-title":"Effects of prenatal marijuana exposure on neuropsychological outcomes in children aged 1-11 years: a systematic review.","volume":"32","author":"Sharapova","year":"2018","journal-title":"Paediatr Perinat Epidemiol"},{"issue":"4","key":"zoi251300r10","doi-asserted-by":"publisher","first-page":"e205","DOI":"10.1097\/AOG.0000000000002354","article-title":"Committee opinion No. 722: marijuana use during pregnancy and lactation.","volume":"130","author":"Committee on Obstetric Practice","year":"2017","journal-title":"Obstet Gynecol"},{"issue":"3","key":"zoi251300r12","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2018-1889","article-title":"Marijuana use during pregnancy and breastfeeding: implications for neonatal and childhood outcomes.","volume":"142","author":"Ryan","year":"2018","journal-title":"Pediatrics"},{"issue":"9","key":"zoi251300r13","doi-asserted-by":"publisher","first-page":"1083","DOI":"10.1001\/jamainternmed.2024.3270","article-title":"Prenatal cannabis use and maternal pregnancy outcomes.","volume":"184","author":"Young-Wolff","year":"2024","journal-title":"JAMA Intern Med"},{"key":"zoi251300r15","doi-asserted-by":"publisher","DOI":"10.1016\/j.abrep.2022.100416","article-title":"Modes of cannabis administration in the year prior to conception among patients in Northern California.","volume":"15","author":"Young-Wolff","year":"2022","journal-title":"Addict Behav Rep"},{"issue":"7","key":"zoi251300r16","doi-asserted-by":"publisher","first-page":"1221","DOI":"10.1111\/j.1360-0443.2012.03837.x","article-title":"The co-occurring use and misuse of cannabis and tobacco: a review.","volume":"107","author":"Agrawal","year":"2012","journal-title":"Addiction"},{"issue":"8","key":"zoi251300r17","doi-asserted-by":"publisher","first-page":"1404","DOI":"10.1111\/j.1360-0443.2012.03843.x","article-title":"Clinical correlates of co-occurring cannabis and tobacco use: a systematic review.","volume":"107","author":"Peters","year":"2012","journal-title":"Addiction"},{"issue":"2","key":"zoi251300r18","doi-asserted-by":"publisher","first-page":"105","DOI":"10.1016\/j.cpr.2011.12.002","article-title":"Tobacco and marijuana use among adolescents and young adults: a systematic review of their co-use.","volume":"32","author":"Ramo","year":"2012","journal-title":"Clin Psychol Rev"},{"issue":"10","key":"zoi251300r19","doi-asserted-by":"publisher","first-page":"1464","DOI":"10.1016\/j.addbeh.2014.05.024","article-title":"Marijuana use and intoxication among daily users: an intensive longitudinal study.","volume":"39","author":"Hughes","year":"2014","journal-title":"Addict Behav"},{"key":"zoi251300r20","doi-asserted-by":"publisher","first-page":"87","DOI":"10.1016\/j.drugpo.2017.11.008","article-title":"Routes of administration for cannabis use\u2014basic prevalence and related health outcomes: a scoping review and synthesis.","volume":"52","author":"Russell","year":"2018","journal-title":"Int J Drug Policy"},{"issue":"4","key":"zoi251300r21","doi-asserted-by":"publisher","first-page":"374","DOI":"10.3109\/14659891.2015.1037365","article-title":"The truth about marijuana is all rolled up in a blunt: prevalence and predictors of blunt use among young African\u2013American adults.","volume":"21","author":"Montgomery","year":"2016","journal-title":"J Subst Use"},{"issue":"3","key":"zoi251300r22","doi-asserted-by":"publisher","first-page":"401","DOI":"10.1080\/10826080802347651","article-title":"A comparison of drug use and dependence between blunt smokers and other cannabis users.","volume":"44","author":"Timberlake","year":"2009","journal-title":"Subst Use Misuse"},{"issue":"1-3","key":"zoi251300r23","doi-asserted-by":"publisher","first-page":"129","DOI":"10.1016\/j.drugalcdep.2012.10.022","article-title":"The changing demographic of blunt smokers across birth cohorts.","volume":"130","author":"Timberlake","year":"2013","journal-title":"Drug Alcohol Depend"},{"issue":"5","key":"zoi251300r24","doi-asserted-by":"publisher","first-page":"105","DOI":"10.1016\/j.drugalcdep.2015.12.017","article-title":"Characterizing substance use and mental health profiles of cigar, blunt, and non-blunt marijuana users from the National Survey of Drug Use and Health.","volume":"160","author":"Cohn","year":"2016","journal-title":"Drug Alcohol Depend"},{"issue":"3","key":"zoi251300r25","doi-asserted-by":"publisher","first-page":"199","DOI":"10.1016\/j.drugalcdep.2008.01.011","article-title":"Smoking tobacco along with marijuana increases symptoms of cannabis dependence.","volume":"95","author":"Ream","year":"2008","journal-title":"Drug Alcohol Depend"},{"key":"zoi251300r26","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2016.05.044","article-title":"Marijuana use and its effects in pregnancy.","author":"Chabarria","year":"2016","journal-title":"Am J Obstet Gynecol"},{"issue":"3","key":"zoi251300r27","doi-asserted-by":"publisher","first-page":"242","DOI":"10.18001\/TRS.5.3.3","article-title":"Harm perceptions of alternative tobacco products among US adolescents.","volume":"5","author":"Kong","year":"2019","journal-title":"Tob Regul Sci"},{"issue":"2","key":"zoi251300r28","doi-asserted-by":"publisher","first-page":"443","DOI":"10.1007\/s11606-024-08980-8","article-title":"Blunt talk on \u201cblunts\u201d: the increasingly popular tobacco product that is potentially exacerbating tobacco-related health disparities.","volume":"40","author":"Sanchez","year":"2025","journal-title":"J Gen Intern Med"},{"issue":"2","key":"zoi251300r29","doi-asserted-by":"publisher","first-page":"608","DOI":"10.1093\/ntr\/nts178","article-title":"Flavored cigar smoking among U.S. adults: findings from the 2009-2010 National Adult Tobacco Survey.","volume":"15","author":"King","year":"2013","journal-title":"Nicotine Tob Res"},{"key":"zoi251300r30","doi-asserted-by":"publisher","DOI":"10.1016\/S2215-0366(16)30208-5","article-title":"Marijuana use and use disorders in adults in the USA, 2002-14: analysis of annual cross-sectional surveys.","author":"Compton","year":"2016","journal-title":"Lancet Psychiatry"},{"issue":"11","key":"zoi251300r31","doi-asserted-by":"publisher","first-page":"1","DOI":"10.15585\/mmwr.ss6511a1","article-title":"National estimates of marijuana use and related indicators\u2014National Survey on Drug Use and Health, United States, 2002-2014.","volume":"65","author":"Azofeifa","year":"2016","journal-title":"MMWR Surveill Summ"},{"key":"zoi251300r32","doi-asserted-by":"publisher","first-page":"232","DOI":"10.1016\/j.drugalcdep.2015.02.009","article-title":"Perceived risk of regular cannabis use in the United States from 2002 to 2012: differences by sex, age, and race\/ethnicity.","volume":"149","author":"Pacek","year":"2015","journal-title":"Drug Alcohol Depend"},{"issue":"1","key":"zoi251300r33","doi-asserted-by":"publisher","first-page":"177","DOI":"10.1007\/s11126-015-9369-z","article-title":"The formation of marijuana risk perception in a population of substance abusing patients.","volume":"87","author":"Wilkinson","year":"2016","journal-title":"Psychiatr Q"},{"issue":"12","key":"zoi251300r34","doi-asserted-by":"publisher","first-page":"2167","DOI":"10.1111\/add.13886","article-title":"Variation in cannabis potency and prices in a newly legal market: evidence from 30 million cannabis sales in Washington state.","volume":"112","author":"Smart","year":"2017","journal-title":"Addiction"},{"issue":"8","key":"zoi251300r35","doi-asserted-by":"publisher","first-page":"643","DOI":"10.1016\/S2215-0366(17)30075-5","article-title":"Can we make cannabis safer?","volume":"4","author":"Englund","year":"2017","journal-title":"Lancet Psychiatry"},{"issue":"3","key":"zoi251300r36","doi-asserted-by":"publisher","first-page":"424","DOI":"10.1016\/j.drugpo.2014.01.017","article-title":"Correlates of intentions to use cannabis among US high school seniors in the case of cannabis legalization.","volume":"25","author":"Palamar","year":"2014","journal-title":"Int J Drug Policy"},{"issue":"1","key":"zoi251300r37","doi-asserted-by":"publisher","first-page":"15","DOI":"10.15288\/jsad.2019.80.15","article-title":"Reasons high school students use marijuana: prevalence and correlations with use across four decades.","volume":"80","author":"Patrick","year":"2019","journal-title":"J Stud Alcohol Drugs"},{"key":"zoi251300r38","doi-asserted-by":"publisher","DOI":"10.5888\/pcd17.190206","article-title":"Youth exposure to marijuana advertising in Oregon\u2019s legal retail marijuana market.","volume":"17","author":"Fiala","year":"2020","journal-title":"Prev Chronic Dis"},{"key":"zoi251300r39","doi-asserted-by":"publisher","first-page":"e104","DOI":"10.1016\/j.drugalcdep.2015.07.290","article-title":"A comparison of meconium screening outcomes as an indicator of the impact of state-level relaxation of marijuana policy.","volume":"156","author":"Jones","year":"2015","journal-title":"Drug Alcohol Depend"},{"issue":"3","key":"zoi251300r40","doi-asserted-by":"publisher","first-page":"211","DOI":"10.1097\/ADM.0000000000000299","article-title":"Pregnant women\u2019s current and intended cannabis use in relation to their views toward legalization and knowledge of potential harm.","volume":"11","author":"Mark","year":"2017","journal-title":"J Addict Med"},{"issue":"12","key":"zoi251300r41","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2022.46912","article-title":"Perceptions about cannabis following legalization among pregnant individuals with prenatal cannabis use in California.","volume":"5","author":"Young-Wolff","year":"2022","journal-title":"JAMA Netw Open"},{"issue":"6","key":"zoi251300r42","doi-asserted-by":"publisher","first-page":"1031","DOI":"10.1097\/AOG.0000000000002619","article-title":"Recommendations from cannabis dispensaries about first-trimester cannabis use.","volume":"131","author":"Dickson","year":"2018","journal-title":"Obstet Gynecol"},{"issue":"1","key":"zoi251300r43","doi-asserted-by":"publisher","first-page":"100","DOI":"10.15288\/jsad.23-00034","article-title":"Cannabis retailer communication about cannabis products, health benefits, and risks: a mystery shopper study of licensed retailers in five U.S. cities.","volume":"85","author":"Romm","year":"2024","journal-title":"J Stud Alcohol Drugs"},{"issue":"11","key":"zoi251300r44","doi-asserted-by":"publisher","first-page":"e1787","DOI":"10.1200\/OP.22.00129","article-title":"Backgrounds and trainings in cannabis therapeutics of dispensary personnel.","volume":"18","author":"Braun","year":"2022","journal-title":"JCO Oncol Pract"},{"issue":"9","key":"zoi251300r45","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2021.24511","article-title":"Analysis of state cannabis laws and dispensary staff recommendations to adults purchasing medical cannabis.","volume":"4","author":"Merlin","year":"2021","journal-title":"JAMA Netw Open"},{"issue":"1","key":"zoi251300r46","doi-asserted-by":"publisher","first-page":"34","DOI":"10.1080\/02791072.2021.1900628","article-title":"Cannabis retail staff (\u201cbudtenders\u201d) attitudes towards cannabis effects on health and experiences interacting with consumers\u2014Washington State, USA.","volume":"54","author":"Carlini","year":"2022","journal-title":"J Psychoactive Drugs"},{"key":"zoi251300r48","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2015.03.021","article-title":"Prevalence and patterns of marijuana use among pregnant and nonpregnant women of reproductive age.","author":"Ko","year":"2015","journal-title":"Am J Obstet Gynecol"},{"key":"zoi251300r49","doi-asserted-by":"publisher","first-page":"18","DOI":"10.1016\/j.addbeh.2015.06.046","article-title":"Marijuana and tobacco use and co-use among African Americans: results from the 2013, National Survey on Drug Use and Health.","volume":"51","author":"Montgomery","year":"2015","journal-title":"Addict Behav"},{"key":"zoi251300r5","unstructured":"Substance Abuse and Mental Health Services Administration. Key substance use and mental health indicators in the United States: key results from the 2023 National Survey on Drug Use and Health. 2024. Accessed December 6, 2024. https:\/\/www.samhsa.gov\/data\/report\/2023-nsduh-annual-national-report"},{"key":"zoi251300r11","unstructured":"National Academies of Sciences, Engineering, and Medicine. The health effects of cannabis and cannabinoids: the current state of evidence and recommendations for research. 2017. Accessed November 4, 2025. https:\/\/nap.nationalacademies.org\/catalog\/24625\/the-health-effects-of-cannabis-and-cannabinoids-the-current-state"},{"key":"zoi251300r14","unstructured":"Centers for Disease Control and Prevention. Marijuana use and pregnancy. Accessed November 4, 2025. https:\/\/www.cdc.gov\/marijuana\/factsheets\/pdf\/MarijuanaFactSheets-Pregnancy-508compliant.pdf"},{"key":"zoi251300r47","unstructured":"California Senate Bill. SB 540: cannabis and cannabis products: health warnings. 2024. Accessed November 4, 2025. https:\/\/calmatters.digitaldemocracy.org\/bills\/ca_202320240sb540?utm"}],"container-title":["JAMA Network Open"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/jamanetwork.com\/journals\/jamanetworkopen\/articlepdf\/2842585\/youngwolff_2025_oi_251300_1764800078.24314.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,10]],"date-time":"2025-12-10T16:00:37Z","timestamp":1765382437000},"score":1,"resource":{"primary":{"URL":"https:\/\/jamanetwork.com\/journals\/jamanetworkopen\/fullarticle\/2842585"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12,10]]},"references-count":49,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2025,12,1]]}},"URL":"https:\/\/doi.org\/10.1001\/jamanetworkopen.2025.48373","relation":{},"ISSN":["2574-3805"],"issn-type":[{"value":"2574-3805","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,12,10]]}}}