{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,9]],"date-time":"2026-05-09T21:48:00Z","timestamp":1778363280928,"version":"3.51.4"},"reference-count":34,"publisher":"American Medical Association (AMA)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JAMA Netw Open"],"abstract":"<jats:sec id=\"ab-zoi251597-4\">\n                    <jats:title>Importance<\/jats:title>\n                    <jats:p>Early parental recognition of severe illness in children and adolescents is crucial for timely management and improved outcomes in pediatric emergency care.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"ab-zoi251597-5\">\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To assess how accurately parents can identify severe illness in their children using a questionnaire completed shortly after arrival at the emergency department (ED).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"ab-zoi251597-6\">\n                    <jats:title>Design, Setting, and Participants<\/jats:title>\n                    <jats:p>This diagnostic study was conducted in a tertiary pediatric ED in northern Finland. Data were collected in 2019 to 2021, and this analysis was conducted in May 2024 to May 2025. Children and adolescents whose parents completed the questionnaire before physician assessment were included.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"ab-zoi251597-7\">\n                    <jats:title>Exposures<\/jats:title>\n                    <jats:p>A structured, 36-item parental questionnaire assessing symptoms and the child or adolescent\u2019s overall condition.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"ab-zoi251597-8\">\n                    <jats:title>Main Outcomes and Measures<\/jats:title>\n                    <jats:p>Severe illness was defined as 1 or more of the following: admission to the pediatric intensive care unit, hospital treatment of more than 24 hours, need for intravenous or nasogastric fluids, need for intravenous antibiotics for more than 24 hours, oxygen saturation less than 93% or the need for inhaled medications, anaphylactic shock, intoxication requiring hospital admission, or surgical intervention. Sensitivity and specificity were calculated for each question. To identify parental triage questions with the strongest diagnostic value, a machine learning analysis was conducted.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"ab-zoi251597-9\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Among 2375 included children and adolescents (mean [SD] age, 5.4 [4.6] years; 1140 female [48.0%]), 567 individuals (23.9%) met criteria for severe illness. Moderate to high parental worry showed the highest sensitivity (91.0% [95% CI, 88.3%-93.2%]) but the lowest specificity (17.5% [95% CI, 15.8%-19.4%]). Other specific pediatric questions demonstrated modest diagnostic accuracy with limited additional value. The machine learning model (area under the receiver operating characteristic curve, 0.71; 95% CI, 0.65-0.77) identified parental worry (feature importance score, 0.047), parent assessments of child or adolescent\u2019s general condition (feature importance score, 0.046), and need for treatment (feature importance score, 0.141) as the strongest predictors of hospital admission.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"ab-zoi251597-10\">\n                    <jats:title>Conclusions and Relevance<\/jats:title>\n                    <jats:p>In this study, parental worry identified most cases of severe illness but had low specificity. These findings suggest that while parental concern may serve as an initial screening indicator, it should be complemented by clinical evaluation and objective measures to avoid unnecessary escalation of care.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1001\/jamanetworkopen.2025.59998","type":"journal-article","created":{"date-parts":[[2026,2,17]],"date-time":"2026-02-17T16:30:22Z","timestamp":1771345822000},"page":"e2559998","source":"Crossref","is-referenced-by-count":2,"title":["Parental Ability to Identify Severe Illnesses in Their Children"],"prefix":"10.1001","volume":"9","author":[{"given":"Hilla","family":"P\u00f6yry","sequence":"first","affiliation":[{"name":"Department of Pediatrics and Adolescent Medicine, Oulu University Hospital, Oulu, Finland"},{"name":"Medical Research Center, Oulu University Hospital, Oulu, Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jenni","family":"Turunen","sequence":"additional","affiliation":[{"name":"Medical 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