{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T16:13:52Z","timestamp":1774628032169,"version":"3.50.1"},"reference-count":56,"publisher":"American Medical Association (AMA)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JAMA Netw Open"],"abstract":"\n Importance<\/jats:title>\n Posttraumatic stress disorder (PTSD) increases the risk of obesity and is associated with less weight loss in the Veterans Health Administration\u2019s (VHA\u2019s) weight management program (MOVE!). MOVE!+UP was developed to address unique barriers to weight loss among veterans with PTSD and elevated body mass index.<\/jats:p>\n <\/jats:sec>\n \n Objective<\/jats:title>\n To examine whether weight change differed between MOVE!+UP and MOVE! participants.<\/jats:p>\n <\/jats:sec>\n \n Design, Setting, and Participants<\/jats:title>\n This randomized clinical trial was conducted from October 6, 2020, to February 28, 2024, at 1 VHA site. Six- and 12-month outcomes were collected by masked assessors. Participants were veterans with PTSD and a body mass index of 25 or greater who were engaged in PTSD care.<\/jats:p>\n <\/jats:sec>\n \n Interventions<\/jats:title>\n Participants were randomly assigned to MOVE!+UP or MOVE!. Both groups received 16 weekly sessions of group-based standard behavioral weight management counseling via video. MOVE!+UP included cognitive behavior therapy\u2013based content (eg, coping, relationship support, and community engagement) and a community-based walk to facilitate exercise and exposure to feared experiences (a PTSD treatment target). MOVE!+UP offered 2 individualized dietitian sessions to enhance benefit.<\/jats:p>\n <\/jats:sec>\n \n Main Outcomes and Measures<\/jats:title>\n The prespecified primary outcome was weight change at 6 months measured on a scale provided by the study.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n Among 174 randomized participants (mean [SD] age, 55 [13] years; 113 men [65%]; 85 participants randomized to MOVE!+UP and 89 randomized to MOVE!), unadjusted mean (SD) weight loss at 6 months among MOVE!+UP participants was 8.9 (13.7) lb (decreased from 224.0 [42.0] to 215.1 [38.1] lb compared with 7.8 [13.8] lb among MOVE! participants (decreased from 232.9 [48.4] to 225.2 [50.2] lb). Adjusted intervention minus control mean weight change was \u22121.5 lb (95% CI, \u22125.9 to 2.9;\n P<\/jats:italic>\n \u2009=\u2009.50). Secondary outcomes (change in PTSD symptoms at 6 and 12 months and weight change at 12 months) did not significantly differ between groups. No participants were withdrawn due to adverse events.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions and Relevance<\/jats:title>\n In this randomized clinical trial, weight change did not differ between a tailored weight management program for veterans with PTSD (MOVE!+UP) and VHA\u2019s standard weight management program (MOVE!). These results suggest that research must continue to address weight loss among those with PTSD.<\/jats:p>\n <\/jats:sec>\n \n Trial Registration<\/jats:title>\n \n ClinicalTrials.gov Identifier:\n NCT04563741<\/jats:ext-link>\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1001\/jamanetworkopen.2026.1904","type":"journal-article","created":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T15:30:27Z","timestamp":1774625427000},"page":"e261904","source":"Crossref","is-referenced-by-count":0,"title":["Enhanced Weight Management Program for Veterans With Posttraumatic Stress Disorder"],"prefix":"10.1001","volume":"9","author":[{"given":"Katherine D.","family":"Hoerster","sequence":"first","affiliation":[{"name":"Mental Health Service, Veterans Affairs (VA) Puget Sound Healthcare System, Seattle Division, Seattle, Washington"},{"name":"Research and Development, VA Puget Sound Healthcare System, Seattle Division, Seattle, Washington"},{"name":"Department of Psychiatry and Behavioral Sciences, 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