{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T15:49:01Z","timestamp":1792511341543,"version":"4.5.0"},"reference-count":263,"publisher":"American Medical Association (AMA)","issue":"10","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JAMA Netw Open"],"abstract":"<jats:sec id=\"ab-zoi261045-4\">\n                    <jats:title>Importance<\/jats:title>\n                    <jats:p>Psilocybin has received increased attention as a potential therapeutic intervention, but it is unclear whether news media reporting reflects the strengths and limitations of the clinical trial evidence.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"ab-zoi261045-5\">\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To describe the annual counts of published clinical trials of therapeutic psilocybin and contemporaneous media articles and compare tone, efficacy, and safety messaging.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"ab-zoi261045-6\">\n                    <jats:title>Evidence Review<\/jats:title>\n                    <jats:p>This systematic review included English-language randomized and nonrandomized trials of psilocybin for clinical indications published from January 1, 2014, to October 10, 2024, and media articles describing its clinical use published from January 1, 2014, to April 22, 2025. Trials were found by searching Medline, Embase, PsycInfo, and the Cochrane Central Register of Controlled Trials (CENTRAL) and were characterized by design, indication, use of psychotherapy, and reporting of efficacy and safety. Media articles were found through the Factiva database and were characterized by audience, tone, indication, efficacy claim, and safety content. Data were extracted by 2 reviewers. Risk of bias for randomized clinical trials was assessed descriptively using the Cochrane Risk of Bias tool.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"ab-zoi261045-7\">\n                    <jats:title>Findings<\/jats:title>\n                    <jats:p>Annual counts of both published clinical trials (n\u2009=\u200970) and media reports (n\u2009=\u2009172) increased from 2018 onward. Depression was the most common clinical indication in trials (47 [67%]) and media articles (138 [80%]), while media articles frequently referenced posttraumatic stress disorder (PTSD) (74 [43%]) and anxiety (72 [42%]) as clinical indications despite absent and limited trial evidence, respectively, for these conditions. Overall, 49 trials (70%) reported benefit for the primary indication; 125 media articles (73%) made at least 1 positive efficacy claim, and 122 (71%) adopted a favorable tone. Trials typically described small sample sizes of less than 100 participants (65 trials [93%]) and methodologic limitations. Overall, 31 trials (44%) reported safety outcomes, with some (24 [34%]) documenting short-term adverse events, such as transient anxiety, nausea, or headache; long-term safety was rarely assessed (4 trials [6%]). Only 51 media articles (30%) mentioned safety; when harms were discussed, potential long-term psychological risks were sometimes noted (12 articles [7%]).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"ab-zoi261045-8\">\n                    <jats:title>Conclusions and Relevance<\/jats:title>\n                    <jats:p>In this systematic review of clinical trials and media articles, both reported positive effects of therapeutic psilocybin with similar frequency. Academic publications were more cautious and explicit about methodologic limitations, whereas media reports often presented benefits as established, extrapolated them to indications with little or no trial evidence, and provided less safety information. Clarifying these differences in emphasis may support more transparent public communication of indication-specific evidence and uncertainty as interest in psilocybin-assisted treatments grows.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1001\/jamanetworkopen.2026.38843","type":"journal-article","created":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T15:30:15Z","timestamp":1792510215000},"page":"e2638843","source":"Crossref","is-referenced-by-count":0,"title":["Clinical Evidence on Psilocybin and Its Representation in Media Reporting"],"prefix":"10.1001","volume":"9","author":[{"given":"Kim","family":"Madden","sequence":"first","affiliation":[{"name":"Department of Anesthesia, McMaster University, Hamilton, Ontario, Canada"},{"name":"Department of Surgery, McMaster University, Hamilton, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Breanne","family":"Flood","sequence":"additional","affiliation":[{"name":"Research Institute of St Joseph\u2019s Hamilton, Hamilton, Ontario, Canada"},{"name":"Centre for Health Research and Innovations on Psychedelics, St Joseph\u2019s Healthcare Hamilton, Hamilton, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Imad","family":"Kashir","sequence":"additional","affiliation":[{"name":"Research Institute of St Joseph\u2019s Hamilton, Hamilton, Ontario, Canada"},{"name":"Centre for Health Research and Innovations on Psychedelics, St Joseph\u2019s Healthcare Hamilton, Hamilton, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rayan","family":"Ahmad","sequence":"additional","affiliation":[{"name":"School of Public Health Sciences, University of Waterloo, Waterloo, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiba","family":"Ali","sequence":"additional","affiliation":[{"name":"School of Public Health Sciences, University of Waterloo, Waterloo, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rotem","family":"Petranker","sequence":"additional","affiliation":[{"name":"Department of Surgery, McMaster University, Hamilton, Ontario, Canada"},{"name":"Centre for Health Research and Innovations on Psychedelics, St Joseph\u2019s Healthcare Hamilton, Hamilton, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James","family":"MacKillop","sequence":"additional","affiliation":[{"name":"Department of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, Ontario, Canada"},{"name":"Peter Boris Centre for Addictions Research, McMaster University & St. Joseph\u2019s Healthcare Hamilton, Hamilton, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anthony","family":"Adili","sequence":"additional","affiliation":[{"name":"Department of Surgery, McMaster University, Hamilton, Ontario, Canada"},{"name":"Research Institute of St Joseph\u2019s 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Could psilocybin be a game-changer for millions battling depression? new study says yes. Benzinga. October 8, 2024. Accessed November 7, 2024. https:\/\/www.benzinga.com\/markets\/cannabis\/24\/10\/41216395\/could-psilocybin-be-a-game-changer-for-millions-battling-depression-new-study-says-yes"},{"key":"zoi261045r131","unstructured":"Could psychedelic experiences help combat anxiety and depression? CE Noticias Financieras. February 25, 2023. Accessed November 7, 2024. https:\/\/www.proquest.com\/docview\/2780173852"},{"key":"zoi261045r132","unstructured":"Cuncliffe? R. David Nutt: \u201cit\u2019s the biggest breakthrough in mental health for 50 years.\u201d The New Statesman. July 20, 2023. Accessed November 7, 2024. https:\/\/www.newstatesman.com\/encounter\/2023\/07\/david-nutt-interview-depression-treatment-mental-health"},{"key":"zoi261045r133","unstructured":"Morin? R. Do psychedelic drug laws violate human rights? The Atlantic. March 4, 2016. Accessed November 7, 2024. https:\/\/www.theatlantic.com\/health\/archive\/2016\/03\/psychedelic-drugs\/471603\/"},{"key":"zoi261045r134","unstructured":"Grochowski? S. Docs regain access to psychedelics: psilocybin, MDMA considered for patients with treatment-resistant mental-health illnesses. The Province. January 18, 2022. Accessed November 7, 2024. https:\/\/www.pressreader.com\/canada\/the-province\/20220118\/281526524424413?srsltid=AU7gw4XMFtwgr0RufwioUxjSuw3LHiyzmye56zbmb8mGtsoKRBbZjtJd"},{"key":"zoi261045r135","unstructured":"Lee? M. Doctors urge access to psychedelic therapies in New Mexico. AP News. July 13, 2022. Accessed November 7, 2024. https:\/\/apnews.com\/article\/health-new-mexico-santa-fe-alcoholism-0f519c0b39bac254bbd705542d7bfabc"},{"key":"zoi261045r136","unstructured":"Experts call for psychedelics to be investigated as cancer distress treatments. PsychedelicNewsWire. August 22, 2023. 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Accessed November 7, 2024. https:\/\/www.stalbertgazette.com\/local-news\/inside-albertas-promising-psychedelic-assisted-therapy-industry-8541878"},{"key":"zoi261045r162","unstructured":"Brown? EN. Inside the growing wellness trend of psilocybin mushroom microdosing. The Hollywood Reporter. January 23, 2022. Accessed November 7, 2024. https:\/\/www.hollywoodreporter.com\/lifestyle\/lifestyle-news\/pyschedelic-mushrooms-microdosing-medical-treatment-1235076616\/"},{"key":"zoi261045r163","unstructured":"It\u2019s time to unshackle psilocybin for research. The Capital Times & Wisconsin State Journal. June 2, 2024. Accessed November 7, 2024. https:\/\/global-factiva-com.libaccess.lib.mcmaster.ca\/hp\/printsavews.aspx?ppstype=Article&pp=Save&hc=Publication"},{"key":"zoi261045r164","unstructured":"Scharper? J. Preparing for a new era of psychedelic treatment. Johns Hopkins Magazine. September 9, 2022. 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Accessed November 7, 2024. https:\/\/www.sltrib.com\/opinion\/letters\/2023\/07\/05\/letter-new-hope-mental-health-utah\/"},{"key":"zoi261045r168","unstructured":"Cook? K. Letter: therapeutic use of psychedelic medicine is very promising\u2014research must not be stymied. The Salt Lake Tribune. September 18, 2024. Accessed November 7, 2024. https:\/\/www.sltrib.com\/opinion\/letters\/2024\/09\/18\/letter-therapeutic-use-psychedelic\/"},{"key":"zoi261045r169","unstructured":"Goldstein? L. Link between cancer and psilocybin: research on this palliative promise. Benzinga. May 23, 2023. Accessed November 7, 2024. https:\/\/www.benzinga.com\/markets\/cannabis\/23\/05\/32495150\/link-between-cancer-and-psilocybin-research-on-this-palliative-promise"},{"key":"zoi261045r170","unstructured":"Wang? Z. London start-up starts testing psychedelics to treat mental conditions. The Standard. October 10, 2022. Accessed November 7, 2024. https:\/\/www.standard.co.uk\/news\/tech\/psychedelics-mental-conditions-treatment-london-b1031580.html"},{"key":"zoi261045r171","unstructured":"Wilson? J. Long, strange trip kicked off the journey to recovery. The Sydney Morning Herald. March 3, 2020. Accessed November 7, 2024. https:\/\/global-factiva-com.libaccess.lib.mcmaster.ca\/hp\/printsavews.aspx?ppstype=Article&pp=Print&hc=Publication"},{"key":"zoi261045r172","unstructured":"Madrigal Mental Care develops treatment for post-traumatic stress disorder based on psychedelic drugs. PR Newswire. May 9, 2022. Accessed November 7, 2024. https:\/\/www.prnewswire.com\/news-releases\/madrigal-mental-care-develops-treatment-for-post-traumatic-stress-disorder-based-on-psychedelic-drugs-301542361.html"},{"key":"zoi261045r173","unstructured":"Gregory? A. Magic mushroom compound psilocybin found safe for consumption in largest ever controlled study. The Independent. December 19, 2019. Accessed November 7, 2024. https:\/\/www.independent.co.uk\/news\/health\/magic-mushroom-depression-psilocybin-trials-kcl-mental-health-addiction-a9251451.html"},{"key":"zoi261045r174","unstructured":"Sullivan? N. Magic mushrooms and end of life care: Cape Breton psychologist hosting talk about psilocybin benefits on terminally ill people. PNI Atlantic News. February 22, 2024. Accessed November 7, 2024. https:\/\/www.saltwire.com\/atlantic-canada\/news\/magic-mushrooms-and-end-of-life-care-cape-breton-psychologist-hosting-talk-about-psilocybin-benefits-on-terminally-ill-people-100940767\/"},{"key":"zoi261045r175","unstructured":"Nelson? J. Magic mushrooms are a promising treatment for depression, new study finds. Emerge. September 25, 2024. Accessed August 6, 2026. https:\/\/decrypt.co\/251025\/magic-mushrooms-promising-treatment-depression"},{"key":"zoi261045r176","unstructured":"Gallagher? J. Magic mushrooms can \u201creset\u201d depressed brain. BBC News. October 14, 2017. Accessed November 7, 2024. https:\/\/www.bbc.com\/news\/health-41608984"},{"key":"zoi261045r177","unstructured":"Kelland? K. Magic mushrooms could be last resort treatment for severe depression, study finds. The Sydney Morning Herald. May 19, 2016. Accessed November 7, 2024. https:\/\/www.smh.com.au\/healthcare\/magic-mushrooms-could-be-last-resort-treatment-for-severe-depression-study-finds-20160517-goxgnx.html"},{"key":"zoi261045r178","unstructured":"Cannabis.net. Magic mushrooms: a potential cure for color blindness? new case study has interesting results. Benzinga. June 29, 2023. Accessed November 7, 2024. https:\/\/www.benzinga.com\/markets\/cannabis\/23\/06\/33011181\/magic-mushrooms-a-potential-cure-for-color-blindness-new-case-study-has-interesting-results"},{"key":"zoi261045r179","unstructured":"Brubaker? H. Mushrooms\u2019 moment? bill aims to put Pa. ahead in psychedelic research. The Philadelphia Inquirer. November 15, 2021. Accessed November 7, 2024. https:\/\/www.inquirer.com\/business\/health\/psilocybin-research-pennsylvania-veterans-ptsd-depression-suicide-20211115.html"},{"key":"zoi261045r180","doi-asserted-by":"crossref","unstructured":"White? CM. Psychedelics may better treat depression and anxiety symptoms than prescription antidepressants for patients with advanced cancer. The Conversation. April 17, 2023. Accessed November 7, 2024. https:\/\/theconversation.com\/psychedelics-may-better-treat-depression-and-anxiety-symptoms-than-prescription-antidepressants-for-patients-with-advanced-cancer-201937","DOI":"10.64628\/AAI.qnq3qdwtq"},{"key":"zoi261045r181","unstructured":"Farid? F. Psychedelics could help with mental health. AAP Bulletins. May 18, 2022. Accessed September 22, 2026. https:\/\/www.redlandcitybulletin.com.au\/story\/7742659\/psychedelics-could-help-with-mental-health\/"},{"key":"zoi261045r183","unstructured":"Oregon in final challenge to authorize psilocybin from cogumelos. ContentEngine. September 22, 2022. Accessed November 7, 2024. https:\/\/www.proquest.com\/docview\/2717303997"},{"key":"zoi261045r185","unstructured":"Johnson? CK. Believers say microdosing psychedelics helps them: scientists are trying to measure the claims. Associated Press Newswire. April 17, 2025. Accessed November 7, 2024. https:\/\/apnews.com\/article\/microdosing-lsd-mushrooms-psychedelic-psilocybin-390c99ba54ef9d75727f39e2ec78fb34"},{"key":"zoi261045r186","unstructured":"Bartlett? SL. A trip into the fine print of ballot question 4: MA\u2019s proposal to legalize certain natural psychedelic substances. Mondaq. April 2, 2025. Accessed November 7, 2024. https:\/\/www.mondaq.com\/unitedstates\/cannabis-hemp\/1604096\/a-trip-into-the-fine-print-of-ballot-question-4-mas-proposal-to-legalize-certain-natural-psychedelic-substances"},{"key":"zoi261045r188","unstructured":"Carlino? M. Nevada Assembly Bill 378 could help patients access psychedelic therapies. Reason Foundation. March 26, 2025. Accessed November 7, 2024. https:\/\/reason.org\/testimony\/nevada-assembly-bill-378-could-help-patients-access-psychedelic-therapies\/"},{"key":"zoi261045r189","unstructured":"Study finds that the mental wellbeing effects of psilocybin vary by race. Investor Brand Network. March 17, 2025. Accessed November 7, 2024. https:\/\/rss.investorbrandnetwork.com\/ibn-full\/study-finds-that-the-mental-wellbeing-effects-of-psilocybin-vary-by-race\/"},{"key":"zoi261045r190","unstructured":"School of Health Professions. Psychedelic therapy: jury\u2019s still out. Texas Tech University Health Sciences Center Daily Dose. March 12, 2025. Accessed November 7, 2024. https:\/\/www.ttuhsc.edu\/stories\/psychedelic-therapy-jurys-still-out"},{"key":"zoi261045r191","unstructured":"Adelstone? J. Ninth Circuit issues disappointing ruling on terminally ill patients and psilocybin. Mondaq. February 19, 2025. Accessed November 7, 2024. https:\/\/www.mondaq.com\/unitedstates\/healthcare\/1586244\/ninth-circuit-issues-disappointing-ruling-on-terminally-ill-patients-and-psilocybin"},{"key":"zoi261045r192","unstructured":"Clouser? T. From \u201cjust say no\u201d to \u201cmaybe so\u201d? Olympia reconsiders legalizing psychedelics. The Center Square. January 30, 2025. Accessed November 7, 2024. https:\/\/www.thecentersquare.com\/national\/article_1e0683ca-df53-11ef-a4a4-77a2f4145668.html"},{"key":"zoi261045r193","unstructured":"Gelperin? R. The fountainhead of the psychedelic renaissance. The Libertarian Institute. January 16, 2025. Accessed November 7, 2024. https:\/\/libertarianinstitute.org\/articles\/the-fountainhead-of-the-psychedelic-renaissance\/"},{"key":"zoi261045r194","unstructured":"Vrije Universiteit Amsterdam. Brain research with psychedelic substances. Vrije Universiteit Amsterdam. January 13, 2025. Accessed November 7, 2024. https:\/\/vu.nl\/en\/news\/2025\/brain-research-with-psychedelic-substances"},{"key":"zoi261045r197","unstructured":"VA funds first study on psychedelic-assisted therapy for veterans. US Dept of Veterans Affairs. December 3, 2024. Accessed November 7, 2024. https:\/\/news.va.gov\/press-room\/va-funds-first-study-on-psychedelic-assisted-therapy-for-veterans\/"},{"key":"zoi261045r199","unstructured":"Psychedelics task force in Vermont calls for education on harm reduction. Psychedelic News Network. November 20, 2024. Accessed September 22, 2026. https:\/\/www.psychedelicnewswire.com\/psychedelics-task-force-in-vermont-calls-for-education-on-harm-reduction\/"},{"key":"zoi261045r202","unstructured":"Study shows psychedelic therapies for some mental illnesses to be legalized. India Education Diary. June 4, 2023. Accessed November 7, 2024. https:\/\/indiaeducationdiary.in\/study-shows-psychedelic-therapies-for-some-mental-illnesses-to-be-legalized\/"},{"key":"zoi261045r203","unstructured":"Study reveals psilocybin-assisted therapy lessens depressive symptoms in adults with cancer and depression. Asian News International. December 23, 2023. Accessed November 7, 2024. https:\/\/www.aninews.in\/news\/health\/study-reveals-psilocybin-assisted-therapy-lessens-depressive-symptoms-in-adults-with-cancer-depression20231223152248\/"},{"key":"zoi261045r204","unstructured":"Kaufmann? B. Mushrooms\u2019 potential magic in quelling alcohol abuse the focus of U of C researchers. Calgary Herald. March 21, 2024. Accessed November 7, 2024. https:\/\/calgaryherald.com\/news\/local-news\/mushrooms-potential-magic-in-halting-alcohol-abuse"},{"key":"zoi261045r205","unstructured":"Duffy? A. Ottawa\u2019s strange state of psilocybin. Ottawa Citizen. September 16, 2023. Accessed November 7, 2024. https:\/\/ottawacitizen.com\/feature\/ottawas-strange-state-of-psilocybin"},{"key":"zoi261045r206","unstructured":"Kriszenfeld? D, Brown? E. So mushroom to grow: psilocybin and Canada\u2019s regulatory landscape. Mondaq. October 19, 2021. Accessed November 7, 2024. https:\/\/www.mondaq.com\/canada\/healthcare\/1122414\/so-mushroom-to-grow-psilocybin-and-canadas-regulatory-landscape"},{"key":"zoi261045r207","unstructured":"Mushrooms to quit alcohol. ContentEngine. October 2, 2022. Accessed November 7, 2024. https:\/\/www.proquest.com\/docview\/2720820603"},{"key":"zoi261045r208","unstructured":"Cannabis.net. Should I tell my doctor if I take psychedelic shrooms? most people don\u2019t, but... Benzinga. September 25, 2023. Accessed November 7, 2024. https:\/\/www.benzinga.com\/markets\/cannabis\/23\/09\/34702745\/should-i-tell-my-doctor-if-i-take-psychedelic-shrooms-most-people-dont-but"},{"key":"zoi261045r209","unstructured":"Martinovic? J. Seattle physician launches push to reschedule psilocybin for medical use. Benzinga. February 5, 2022. Accessed November 7, 2024. https:\/\/www.benzinga.com\/markets\/cannabis\/22\/02\/25426637\/seattle-physician-launches-push-to-reschedule-psilocybin-for-medical-use"},{"key":"zoi261045r210","unstructured":"Carey? B. Scientists bet on psychedelic drugs to treat mental health problems. New York Times. September 8, 2019. Accessed November 7, 2024. https:\/\/www.proquest.com\/docview\/2287334830"},{"key":"zoi261045r211","unstructured":"Atter? H. Sask. man first in Canada to legally use magic mushrooms in therapy. CBC. August 24, 2020. Accessed November 7, 2024. https:\/\/www.cbc.ca\/news\/canada\/saskatchewan\/thomas-hartle-magic-mushroom-psilocybin-therapy-1.5700371"},{"key":"zoi261045r212","unstructured":"Revive Therapeutics Ltd. Revive Therapeutics files for FDA orphan drug designation for psilocybin in traumatic brain injury. GlobeNewswire. April 27, 2021. 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Psychiatrists split over the use of \u2019shrooms and MDMA to treat mental illness. Crikey. February 12, 2021. Accessed November 7, 2024. https:\/\/www.crikey.com.au\/2021\/02\/12\/psychiatrists-shrooms-mdma-mental-illness\/"},{"key":"zoi261045r216","unstructured":"Khan? I. Psychedelics: expanding the therapeutic toolkit. Prospect. December 8, 2022. Accessed November 7, 2024. https:\/\/www.prospectmagazine.co.uk\/politics\/60295\/psychedelics-expanding-the-therapeutic-toolkit"},{"key":"zoi261045r217","unstructured":"Kalensky? M. Psychedelic-assisted therapy: applications in mental health. Clinical Advisor. April 15, 2022. Accessed November 7, 2024. https:\/\/www.clinicaladvisor.com\/features\/psychedelics-applications-in-mental-health\/"},{"key":"zoi261045r218","unstructured":"Psychedelics may help manage long COVID-19 symptoms. PsychedelicNewsWire. April 21, 2023. 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Psilocybin, from magic mushrooms, eases anxiety and depression in cancer patients. Newsweek. December 16, 2016. Accessed November 7, 2024. https:\/\/www.proquest.com\/docview\/1847774029"},{"key":"zoi261045r239","unstructured":"Psilocybin, another lost opportunity for Mexico? ContentEngine. September 21, 2022. Accessed November 7, 2024. https:\/\/www.proquest.com\/docview\/2716944263"},{"key":"zoi261045r240","unstructured":"Psilocybin-assisted therapy reduces depressive symptoms in adults with cancer, depression: study. Asian News International. December 18, 2023. Accessed September 22, 2026. https:\/\/www.aninews.in\/news\/health\/psilocybin-assisted-therapy-reduces-depressive-symptoms-in-adults-with-cancer-depression-study20231218195421\/"},{"key":"zoi261045r242","unstructured":"Preliminary trial shows psilocybin reduces intensity, magnitude of migraines. PsychedelicNewsWire. August 14, 2023. Accessed November 7, 2024. https:\/\/rss.investorbrandnetwork.com\/pnw-full\/preliminary-trial-shows-psilocybin-reduces-intensity-magnitude-of-migraines\/"},{"key":"zoi261045r243","unstructured":"Mahindra? AS. Over 5 million Americans could benefit if psilocybin is approved for depression, finds study. Times Now. September 16, 2024. Accessed November 7, 2024. https:\/\/www.timesnownews.com\/health\/mental-health\/over-5-million-americans-could-benefit-if-psilocybin-is-approved-for-depression-finds-study-article-113379585"},{"key":"zoi261045r244","unstructured":"Oregon State University. Oregon State research helps provide scientific framework for psilocybin use in therapeutic settings. NewsRx. April 25, 2022. Accessed November 7, 2024. https:\/\/news.oregonstate.edu\/news\/oregon-state-research-helps-provide-scientific-framework-psilocybin-use-therapeutic-settings"},{"key":"zoi261045r245","unstructured":"Obesity enters the psychedelic panacea\u2019s sights. ContentEngine. November 25, 2022. Accessed November 7, 2024. https:\/\/www.proquest.com\/docview\/2740273221"},{"key":"zoi261045r246","unstructured":"New York University. Antianxiety and antidepressant effects from a single dose of psychedelic drug persist years later in cancer patients. ScienceDaily. January 31, 2020. Accessed November 7, 2024. https:\/\/www.sciencedaily.com\/releases\/2020\/01\/200128115423.htm"},{"key":"zoi261045r247","unstructured":"Syal? A. NIH-funded psychedelic trial will study whether hallucinogen can help smokers quit. NBC News. November 4, 2022. Accessed November 7, 2024. https:\/\/www.nbcnews.com\/health\/health-news\/nih-funded-psychedelic-trial-will-study-whether-hallucinogen-can-help-rcna53922"},{"key":"zoi261045r248","unstructured":"Ponieman? N. NIH director praises psychedelics\u2019 potential as therapeutic treatment, touts progress in access to cannabis for research. Benzinga. May 27, 2021. 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Meet the London care providers fighting to prescribe psychedelic mushrooms. CBC News. June 9, 2023. Accessed November 7, 2024. https:\/\/www.cbc.ca\/news\/canada\/london\/meet-the-london-care-providers-fighting-to-prescribe-psychedelic-mushrooms-1.6863827"},{"key":"zoi261045r256","unstructured":"Mammoser? G. Mushrooms as medicine? psychedelics may be next breakthrough treatment. Healthline. February 12, 2019. Accessed November 7, 2024. https:\/\/healthline.com\/health-news\/benefits-of-medical-mushrooms"},{"key":"zoi261045r257","unstructured":"Legge? J. Magical medicine: BC cannabis farmers are ready to safely produce psilocybin. The Abbotsford News. July 27, 2022. Accessed November 7, 2024. https:\/\/abbynews.com\/2022\/07\/27\/magical-medicine-b-c-cannabis-farmers-are-ready-to-safely-produce-psilocybin\/"},{"key":"zoi261045r258","unstructured":"Diwan? P. Magic mushroomsN, LSD can treat anxiety and addictions. TopNews. May 28, 2015. Accessed November 7, 2024. https:\/\/global-factiva-com.libaccess.lib.mcmaster.ca\/hp\/printsavews.aspx?ppstype=Article&pp=Print&hc=Publicatio"},{"key":"zoi261045r262","unstructured":"Samenow D, Kung K, Ludwig R. State psychedelic regulation: Oregon and Colorado taking the lead. DLA Piper. January 11, 2023. 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