{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T02:49:38Z","timestamp":1792464578099,"version":"4.5.0"},"reference-count":33,"publisher":"American Medical Association (AMA)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JAMA Netw Open"],"abstract":"<jats:sec id=\"ab-zoi260207-4\">\n                    <jats:title>Importance<\/jats:title>\n                    <jats:p>Health-related social needs (HRSNs) may impede colorectal cancer (CRC) screening among US adults, yet population-based evidence on these associations remains limited.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"ab-zoi260207-5\">\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To examine associations between HRSNs and CRC screening uptake overall and by age group among US adults.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"ab-zoi260207-6\">\n                    <jats:title>Design, Setting, and Participants<\/jats:title>\n                    <jats:p>This cross-sectional study used data from the 2023 National Health Interview Survey. Participants were US civilian, noninstitutionalized adults aged 45 to 75 years eligible for CRC screening. Age-stratified analyses were conducted for adults aged 45 to 49 years, 50 to 64 years, and 65 to 75 years. Data analysis was performed from April 2025 to February 2026.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"ab-zoi260207-7\">\n                    <jats:title>Exposures<\/jats:title>\n                    <jats:p>Self-reported HRSNs, including housing instability, food insecurity, transportation barriers, and number of unmet needs.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"ab-zoi260207-8\">\n                    <jats:title>Main Outcomes and Measures<\/jats:title>\n                    <jats:p>The primary outcome was being up to date with CRC screening according to US Preventive Services Task Force recommendations. Survey-weighted logistic regression models estimated adjusted odds ratios (aORs) and 95% CIs overall and by age group.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"ab-zoi260207-9\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The analytic sample included 14\u202f528 adults aged 45 to 75 years, and most participants were aged 50 to 64 years (6940 individuals [52.42%]), female (7788 individuals [51.36%]), insured (13\u202f750 participants [94.07%]), and reported no unmet HRSNs (12\u202f370 participants [85.40%]). Overall, 2158 adults (14.60%) reported at least 1 unmet HRSN. The proportion up to date with CRC screening was 63.91% (9758 adults) overall and increased with age, from 31.01% (586 adults) among adults aged 45 to 49 years to 64.24% (4539 adults) among those aged 50 to 64 years, and 80.85% (4633 adults) among those aged 65 to 75 years. In adjusted models, housing instability (aOR, 0.82; 95% CI, 0.67-0.99) and transportation barriers (aOR, 0.78; 95% CI, 0.64-0.95) were associated with lower odds of being up to date with CRC screening. Screening odds declined with increasing number of unmet HRSNs, including among adults reporting 1 unmet need (aOR, 0.84; 95% CI, 0.72-0.98). Associations were most pronounced among adults aged 50 to 64 years, among whom housing instability (aOR, 0.77; 95% CI, 0.61-0.97), transportation barriers (aOR, 0.71; 95% CI, 0.56-0.91), and reporting 1 HRSN (aOR, 0.80; 95% CI, 0.66-0.97) were associated with lower odds of being up to date with screening.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"ab-zoi260207-10\">\n                    <jats:title>Conclusions and Relevance<\/jats:title>\n                    <jats:p>In this cross-sectional study, unmet HRSNs were associated with lower CRC screening uptake, particularly among adults aged 50 to 64 years. Addressing HRSNs may support age-specific strategies to improve CRC screening.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1001\/jamanetworkopen.2026.6000","type":"journal-article","created":{"date-parts":[[2026,4,9]],"date-time":"2026-04-09T15:00:23Z","timestamp":1775746823000},"page":"e266000","source":"Crossref","is-referenced-by-count":3,"title":["Colorectal Cancer Screening and Health-Related Social Needs in a National Sample of US Adults"],"prefix":"10.1001","volume":"9","author":[{"given":"Aldenise P.","family":"Ewing","sequence":"first","affiliation":[{"name":"Division of Epidemiology, The Ohio State University College of Public Health, Columbus"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fode","family":"Tounkara","sequence":"additional","affiliation":[{"name":"The Ohio State University College of Medicine, Columbus"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wayne 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