{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,13]],"date-time":"2026-09-13T11:19:59Z","timestamp":1789298399337,"version":"build-2803163510"},"reference-count":34,"publisher":"American Medical Association (AMA)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JAMA Netw Open"],"abstract":"<jats:sec id=\"ab-zoi260288-4\">\n                    <jats:title>Importance<\/jats:title>\n                    <jats:p>Systemic glucocorticoids have little or no demonstrated efficacy for acute respiratory infections (ARIs) and have known adverse effects. Clinicians in urgent care centers vary widely in their use of glucocorticoids for patients seen for ARIs.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"ab-zoi260288-5\">\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To develop and test a multifaceted urgent care stewardship program to reduce the use of glucocorticoids for ARIs.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"ab-zoi260288-6\">\n                    <jats:title>Design, Setting, and Participants<\/jats:title>\n                    <jats:p>This quality improvement study included clinicians seeing patients from January 2023 through April 2025 presenting with ARIs at 2 urgent care centers within an academic health system.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"ab-zoi260288-7\">\n                    <jats:title>Interventions<\/jats:title>\n                    <jats:p>Beginning in February 2024, clinicians were emailed a survey about steroid stewardship, received brief virtual clinician education, and were provided with educational pamphlets to distribute to patients. In May and December 2024, they received email feedback using peer comparison with descriptive and injunctive norms.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"ab-zoi260288-8\">\n                    <jats:title>Main Outcomes and Measures<\/jats:title>\n                    <jats:p>Segmented Poisson regression with clinician-level random effects was used to analyze monthly clinician-level rates of ARI urgent care visits where a systemic glucocorticoid was prescribed (steroid stewardship\u2013eligible visits) before (January 2023 to January 2024) and after (February 2024 to April 2025) steroid stewardship. Visits were excluded for patients with conditions where glucocorticoid treatment may be clinically appropriate. Retrospective interrupted time series modeling of glucocorticoid prescriptions was performed before and after stewardship program implementation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"ab-zoi260288-9\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      From January 2023 to April 2025, 10\u202f808 patients (mean [SD] age, 58 [24] years; 6879 [64%] female; 3929 [36%] male) were seen for ARI by 96 clinicians (78 [81%] females; 18 [19%] male; 32 [33%] advance practice nurses; 38 [40%] physicians; 26 [27%] physician assistants) presenting with ARIs at 2 urgent care centers within an academic health system. Participating clinicians attended 14\u202f530 steroid stewardship\u2013eligible visits (7130 before and 7400 during stewardship). The most common diagnoses were nonspecific upper respiratory infection (17%), acute pharyngitis (15%), and acute bronchitis (7%). The mean (SD) clinician-level observed rate per 100 stewardship-eligible visits of systemic glucocorticoid prescriptions decreased from 20.4 (17.8) in the period before stewardship to 8.8 (14.5) during the stewardship period (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2009&amp;amp;lt;.001). During the stewardship period, the relative rate of glucocorticoid prescribing decreased by 0.94 (95% CI, 0.92 to 0.96;\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2009&amp;amp;lt;.001) per month compared with the period before stewardship.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"ab-zoi260288-10\">\n                    <jats:title>Conclusions and Relevance<\/jats:title>\n                    <jats:p>In this quality improvement study of a multi-faceted, behavioral science\u2013informed intervention to promote glucocorticoid stewardship for ARIs in urgent care settings, implementation was associated with reductions in glucocorticoid prescribing.<\/jats:p>\n                  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General Internal Medicine; Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ji Young","family":"Lee","sequence":"additional","affiliation":[{"name":"Division of General Internal Medicine; Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucia C.","family":"Petito","sequence":"additional","affiliation":[{"name":"Division of Biostatistics and Informatics, Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffrey A.","family":"Linder","sequence":"additional","affiliation":[{"name":"Division of General Internal Medicine; Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois"},{"name":"Center for Primary Care 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