{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T05:39:40Z","timestamp":1790833180136,"version":"4.1.0"},"reference-count":0,"publisher":"American Medical Association (AMA)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JAMA Neurol"],"published-print":{"date-parts":[[2017,5,1]]},"DOI":"10.1001\/jamaneurol.2016.5953","type":"journal-article","created":{"date-parts":[[2017,3,13]],"date-time":"2017-03-13T17:11:18Z","timestamp":1489425078000},"page":"540","source":"Crossref","is-referenced-by-count":39,"title":["Neurofibrillary Tangle Stage and the Rate of Progression of Alzheimer Symptoms"],"prefix":"10.1001","volume":"74","author":[{"given":"Jing","family":"Qian","sequence":"first","affiliation":[{"name":"Department of Biostatistics and Epidemiology, University of Massachusetts, Amherst"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bradley T.","family":"Hyman","sequence":"additional","affiliation":[{"name":"Neurology Service, Massachusetts General Hospital, Charlestown, Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rebecca A.","family":"Betensky","sequence":"additional","affiliation":[{"name":"Department of Biostatistics, Harvard T. H. Chan School of Public Health, Boston, Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"10","container-title":["JAMA Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/archneur.jamanetwork.com\/ama\/content_public\/journal\/neur\/936193\/jamaneurology_qian_2017_oi_160121.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,7]],"date-time":"2023-04-07T21:35:01Z","timestamp":1680903301000},"score":1,"resource":{"primary":{"URL":"http:\/\/archneur.jamanetwork.com\/article.aspx?doi=10.1001\/jamaneurol.2016.5953"}},"subtitle":["Modeling Using an Autopsy Cohort and Application to Clinical Trial Design"],"short-title":[],"issued":{"date-parts":[[2017,5,1]]},"references-count":0,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2017,5,1]]}},"URL":"https:\/\/doi.org\/10.1001\/jamaneurol.2016.5953","relation":{},"ISSN":["2168-6149"],"issn-type":[{"value":"2168-6149","type":"print"}],"subject":[],"published":{"date-parts":[[2017,5,1]]}}}