{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,6]],"date-time":"2026-11-06T01:43:12Z","timestamp":1793929392876,"version":"4.8.0"},"reference-count":37,"publisher":"American Medical Association (AMA)","issue":"8","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JAMA Oncol"],"published-print":{"date-parts":[[2018,8,1]]},"DOI":"10.1001\/jamaoncol.2018.0644","type":"journal-article","created":{"date-parts":[[2018,5,10]],"date-time":"2018-05-10T16:30:41Z","timestamp":1525969841000},"page":"1066","source":"Crossref","is-referenced-by-count":156,"title":["Uptake, Results, and Outcomes of Germline Multiple-Gene Sequencing After Diagnosis of Breast Cancer"],"prefix":"10.1001","volume":"4","author":[{"given":"Allison W.","family":"Kurian","sequence":"first","affiliation":[{"name":"Departments of Medicine and Health Research and Policy, Stanford University, Stanford, California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kevin C.","family":"Ward","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, Georgia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ann S.","family":"Hamilton","sequence":"additional","affiliation":[{"name":"Department of Preventive Medicine in the Keck School of Medicine, Keck School of Medicine, University of Southern California, Los Angeles"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dennis M.","family":"Deapen","sequence":"additional","affiliation":[{"name":"Department of Preventive Medicine in the Keck School of Medicine, Keck School of Medicine, University of Southern California, Los Angeles"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"Abrahamse","sequence":"additional","affiliation":[{"name":"Department of Biostatistics, School of Public Health, University of Michigan, Ann Arbor"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Irina","family":"Bondarenko","sequence":"additional","affiliation":[{"name":"Department of Biostatistics, School of Public Health, University of Michigan, Ann Arbor"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yun","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Biostatistics, School of Public Health, University of Michigan, Ann Arbor"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah T.","family":"Hawley","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Division of General Medicine, Department of Health Management and Policy, School of Public Health, University of Michigan, Ann Arbor, and Veterans Administration Center for Clinical Management Research, Ann Arbor VA Health Care System, Ann Arbor"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monica","family":"Morrow","sequence":"additional","affiliation":[{"name":"Memorial Sloan-Kettering Cancer Center, Department of Surgery, New York, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Reshma","family":"Jagsi","sequence":"additional","affiliation":[{"name":"Center for Bioethics and Social Science in Medicine, Oncology, Department of Radiation, University of Michigan, Ann Arbor"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven J.","family":"Katz","sequence":"additional","affiliation":[{"name":"Department of Health Management and Policy, School of Public Health, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"10","reference":[{"issue":"10","key":"coi180019r1","doi-asserted-by":"publisher","first-page":"997","DOI":"10.1001\/jama.2015.8088","article-title":"Treatment decision making and genetic testing for breast cancer: mainstreaming mutations.","volume":"314","author":"Katz","year":"2015","journal-title":"JAMA"},{"issue":"20","key":"coi180019r2","doi-asserted-by":"publisher","first-page":"2329","DOI":"10.1200\/JCO.2016.70.3439","article-title":"Traceback: a proposed framework to increase identification and genetic counseling of brca1 and brca2 mutation carriers through family-based outreach.","volume":"35","author":"Samimi","year":"2017","journal-title":"J Clin Oncol"},{"issue":"10","key":"coi180019r3","doi-asserted-by":"publisher","first-page":"1267","DOI":"10.1200\/JCO.2012.46.9403","article-title":"Multiplex genetic testing for cancer susceptibility: out on the high wire without a net?","volume":"31","author":"Domchek","year":"2013","journal-title":"J Clin Oncol"},{"issue":"21","key":"coi180019r4","doi-asserted-by":"publisher","first-page":"2743","DOI":"10.1200\/JCO.2013.49.7388","article-title":"Gene patents and personalized cancer care: impact of the Myriad case on clinical oncology.","volume":"31","author":"Offit","year":"2013","journal-title":"J Clin Oncol"},{"issue":"3","key":"coi180019r5","doi-asserted-by":"publisher","first-page":"277","DOI":"10.1001\/jamaoncol.2015.28","article-title":"Multigene panel testing in oncology practice: how should we respond?","volume":"1","author":"Kurian","year":"2015","journal-title":"JAMA Oncol"},{"issue":"3","key":"coi180019r6","doi-asserted-by":"publisher","first-page":"557","DOI":"10.1007\/s10549-016-4082-7","article-title":"Recurrence risk perception and quality of life following treatment of breast cancer.","volume":"161","author":"Hawley","year":"2017","journal-title":"Breast Cancer Res Treat"},{"issue":"24","key":"coi180019r7","doi-asserted-by":"publisher","first-page":"4791","DOI":"10.1002\/cncr.v123.24","article-title":"Treatment decisions and employment of breast cancer patients: Results of a population-based survey.","volume":"123","author":"Jagsi","year":"2017","journal-title":"Cancer"},{"issue":"3","key":"coi180019r8","doi-asserted-by":"publisher","first-page":"274","DOI":"10.1001\/jamasurg.2016.4749","article-title":"Contralateral prophylactic mastectomy decisions in a population-based sample of patients with early-stage breast cancer.","volume":"152","author":"Jagsi","year":"2017","journal-title":"JAMA Surg"},{"key":"coi180019r9","article-title":"Recent trends in chemotherapy use and oncologists' treatment recommendations for early-stage breast cancer","author":"Kurian","journal-title":"J Natl Cancer Inst"},{"issue":"3","key":"coi180019r10","doi-asserted-by":"publisher","first-page":"391","DOI":"10.1001\/jamaoncol.2016.5652","article-title":"Second opinions from medical oncologists for early-stage breast cancer: prevalence, correlates, and consequences.","volume":"3","author":"Kurian","year":"2017","journal-title":"JAMA Oncol"},{"issue":"5","key":"coi180019r11","doi-asserted-by":"publisher","first-page":"531","DOI":"10.1001\/jama.2016.16918","article-title":"Genetic testing and counseling among patients with newly diagnosed breast cancer.","volume":"317","author":"Kurian","year":"2017","journal-title":"JAMA"},{"issue":"20","key":"coi180019r12","doi-asserted-by":"publisher","first-page":"2232","DOI":"10.1200\/JCO.2016.71.6480","article-title":"Gaps in incorporating germline genetic testing into treatment decision-making for early-stage breast cancer.","volume":"35","author":"Kurian","year":"2017","journal-title":"J Clin Oncol"},{"issue":"5","key":"coi180019r15","doi-asserted-by":"publisher","first-page":"405","DOI":"10.1038\/gim.2015.30","article-title":"Standards and guidelines for the interpretation of sequence variants: a joint consensus recommendation of the American College of Medical Genetics and Genomics and the Association for Molecular Pathology.","volume":"17","author":"Richards","year":"2015","journal-title":"Genet Med"},{"issue":"4","key":"coi180019r16","doi-asserted-by":"publisher","first-page":"294","DOI":"10.1097\/GIM.0b013e31816b5cae","article-title":"ACMG recommendations for standards for interpretation and reporting of sequence variations: revisions 2007.","volume":"10","author":"Richards","year":"2008","journal-title":"Genet Med"},{"issue":"1","key":"coi180019r17","doi-asserted-by":"publisher","first-page":"9","DOI":"10.6004\/jnccn.2017.0003","article-title":"NCCN guidelines insights: genetic\/familial high-risk assessment: breast and ovarian, version 2.2017.","volume":"15","author":"Daly","year":"2017","journal-title":"J Natl Compr Canc Netw"},{"issue":"19","key":"coi180019r18","doi-asserted-by":"publisher","first-page":"2001","DOI":"10.1200\/JCO.2013.53.6607","article-title":"Clinical evaluation of a multiple-gene sequencing panel for hereditary cancer risk assessment.","volume":"32","author":"Kurian","year":"2014","journal-title":"J Clin Oncol"},{"issue":"1","key":"coi180019r19","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1002\/cncr.29010","article-title":"Frequency of mutations in individuals with breast cancer referred for BRCA1 and BRCA2 testing using next-generation sequencing with a 25-gene panel.","volume":"121","author":"Tung","year":"2015","journal-title":"Cancer"},{"issue":"11","key":"coi180019r20","doi-asserted-by":"publisher","first-page":"830","DOI":"10.1038\/gim.2014.40","article-title":"Utilization of multigene panels in hereditary cancer predisposition testing: analysis of more than 2,000 patients.","volume":"16","author":"LaDuca","year":"2014","journal-title":"Genet Med"},{"issue":"7","key":"coi180019r21","doi-asserted-by":"publisher","first-page":"943","DOI":"10.1001\/jamaoncol.2015.2690","article-title":"Clinical actionability of multigene panel testing for hereditary breast and ovarian cancer risk assessment.","volume":"1","author":"Desmond","year":"2015","journal-title":"JAMA Oncol"},{"issue":"8","key":"coi180019r22","doi-asserted-by":"publisher","first-page":"630","DOI":"10.1038\/gim.2014.176","article-title":"Prevalence of mutations in a panel of breast cancer susceptibility genes in BRCA1\/2-negative patients with early-onset breast cancer.","volume":"17","author":"Maxwell","year":"2015","journal-title":"Genet Med"},{"issue":"13","key":"coi180019r23","doi-asserted-by":"publisher","first-page":"1455","DOI":"10.1200\/JCO.2015.63.7454","article-title":"Panel testing for familial breast cancer: calibrating the tension between research and clinical care.","volume":"34","author":"Thompson","year":"2016","journal-title":"J Clin Oncol"},{"issue":"4","key":"coi180019r24","doi-asserted-by":"publisher","first-page":"527","DOI":"10.1007\/s10689-014-9741-4","article-title":"Cancer genetic testing panels for inherited cancer susceptibility: the clinical experience of a large adult genetics practice.","volume":"13","author":"Selkirk","year":"2014","journal-title":"Fam Cancer"},{"issue":"4","key":"coi180019r25","doi-asserted-by":"publisher","first-page":"304","DOI":"10.1200\/JCO.2014.57.1414","article-title":"Inherited mutations in 17 breast cancer susceptibility genes among a large triple-negative breast cancer cohort unselected for family history of breast cancer.","volume":"33","author":"Couch","year":"2015","journal-title":"J Clin Oncol"},{"issue":"9","key":"coi180019r26","doi-asserted-by":"publisher","first-page":"581","DOI":"10.1038\/nrclinonc.2016.90","article-title":"Counselling framework for moderate-penetrance cancer-susceptibility mutations.","volume":"13","author":"Tung","year":"2016","journal-title":"Nat Rev Clin Oncol"},{"issue":"6","key":"coi180019r27","doi-asserted-by":"publisher","first-page":"739","DOI":"10.1038\/ejhg.2014.180","article-title":"A systematic review of factors that act as barriers to patient referral to genetic services.","volume":"23","author":"Delikurt","year":"2015","journal-title":"Eur J Hum Genet"},{"issue":"7","key":"coi180019r28","doi-asserted-by":"publisher","first-page":"655","DOI":"10.1056\/NEJMsa1507092","article-title":"Genetic misdiagnoses and the potential for health disparities.","volume":"375","author":"Manrai","year":"2016","journal-title":"N Engl J Med"},{"issue":"10","key":"coi180019r29","doi-asserted-by":"publisher","first-page":"2222","DOI":"10.1002\/cncr.24200","article-title":"BRCA1 and BRCA2 mutations in women of different ethnicities undergoing testing for hereditary breast-ovarian cancer.","volume":"115","author":"Hall","year":"2009","journal-title":"Cancer"},{"key":"coi180019r30","article-title":"Racial\/ethnic differences in multiple-gene sequencing results for hereditary cancer risk.","author":"Caswell-Jin","journal-title":"Genet Med"},{"issue":"9","key":"coi180019r31","doi-asserted-by":"publisher","first-page":"2017","DOI":"10.1002\/ijc.23340","article-title":"International variation in rates of uptake of preventive options in BRCA1 and BRCA2 mutation carriers.","volume":"122","author":"Metcalfe","year":"2008","journal-title":"Int J Cancer"},{"issue":"12","key":"coi180019r32","doi-asserted-by":"crossref","first-page":"1989","DOI":"10.1158\/1055-9965.1989.13.12","article-title":"Utilization of screening and preventive surgery among unaffected carriers of a BRCA1 or BRCA2 gene mutation.","volume":"13","author":"Wainberg","year":"2004","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"issue":"12","key":"coi180019r33","doi-asserted-by":"publisher","first-page":"1323","DOI":"10.1001\/archsurg.138.12.1323","article-title":"Effect of genetic cancer risk assessment on surgical decisions at breast cancer diagnosis.","volume":"138","author":"Weitzel","year":"2003","journal-title":"Arch Surg"},{"issue":"5","key":"coi180019r34","doi-asserted-by":"publisher","first-page":"367","DOI":"10.1089\/gtmb.2012.0381","article-title":"A statewide survey of practitioners to assess knowledge and clinical practices regarding hereditary breast and ovarian cancer.","volume":"17","author":"Pal","year":"2013","journal-title":"Genet Test Mol Biomarkers"},{"issue":"26","key":"coi180019r35","doi-asserted-by":"publisher","first-page":"4282","DOI":"10.1200\/JCO.2008.16.6231","article-title":"Clinical and pathologic characteristics of patients with BRCA-positive and BRCA-negative breast cancer.","volume":"26","author":"Atchley","year":"2008","journal-title":"J Clin Oncol"},{"issue":"6","key":"coi180019r36","doi-asserted-by":"publisher","first-page":"523","DOI":"10.1056\/NEJMoa1706450","article-title":"Olaparib for metastatic breast cancer in patients with a germline BRCA mutation.","volume":"377","author":"Robson","year":"2017","journal-title":"N Engl J Med"},{"issue":"2","key":"coi180019r37","doi-asserted-by":"publisher","first-page":"69","DOI":"10.7326\/0003-4819-155-2-201107190-00002","article-title":"Strategies to identify the Lynch syndrome among patients with colorectal cancer: a cost-effectiveness analysis.","volume":"155","author":"Ladabaum","year":"2011","journal-title":"Ann Intern Med"},{"key":"coi180019r13","volume-title":"Internet, Mail, and Mixed-Mode Surveys: The Tailored Design Method","author":"Dillman","year":"2009","edition":"3rd ed"},{"key":"coi180019r14","unstructured":"United States Department of Health and Human Services. Guidance Regarding Methods for De-identification of Protected Health Information in Accordance with the Health Insurance Portability and Accountability Act (HIPAA) Privacy Rule. https:\/\/www.hhs.gov\/hipaa\/for-professionals\/privacy\/special-topics\/de-identification\/index.html#safeharborguidance. Accessed January 4, 2018."}],"container-title":["JAMA Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/jamanetwork.com\/journals\/jamaoncology\/fullarticle\/2680748","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,8,23]],"date-time":"2022-08-23T05:59:10Z","timestamp":1661234350000},"score":1,"resource":{"primary":{"URL":"http:\/\/oncology.jamanetwork.com\/article.aspx?doi=10.1001\/jamaoncol.2018.0644"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,8,1]]},"references-count":37,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2018,8,1]]}},"URL":"https:\/\/doi.org\/10.1001\/jamaoncol.2018.0644","relation":{},"ISSN":["2374-2437"],"issn-type":[{"value":"2374-2437","type":"print"}],"subject":[],"published":{"date-parts":[[2018,8,1]]}}}