{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T11:53:16Z","timestamp":1787313196396,"version":"build-2736575974"},"reference-count":20,"publisher":"American Medical Association (AMA)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JAMA Oncol"],"published-print":{"date-parts":[[2019,5,1]]},"DOI":"10.1001\/jamaoncol.2018.7204","type":"journal-article","created":{"date-parts":[[2019,3,7]],"date-time":"2019-03-07T11:52:00Z","timestamp":1551959520000},"page":"703","source":"Crossref","is-referenced-by-count":87,"title":["Association of Neurosurgical Resection With Development of Pachymeningeal Seeding in Patients With Brain Metastases"],"prefix":"10.1001","volume":"5","author":[{"given":"Daniel N.","family":"Cagney","sequence":"first","affiliation":[{"name":"Department of Radiation Oncology, Dana-Farber\/Brigham and Women\u2019s Cancer Center, Harvard Medical School, Boston, Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nayan","family":"Lamba","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology, Dana-Farber\/Brigham and Women\u2019s Cancer Center, Harvard Medical School, Boston, Massachusetts"},{"name":"Harvard Medical School, Boston, Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sumi","family":"Sinha","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology, University of California, San Francisco, San Francisco"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul J.","family":"Catalano","sequence":"additional","affiliation":[{"name":"Department of Biostatistics, Harvard T. H. Chan School of Public Health, Boston, Massachusetts"},{"name":"Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenya Linda","family":"Bi","sequence":"additional","affiliation":[{"name":"Center for Skull Base and Pituitary Surgery, Department of Neurosurgery, Brigham and Women\u2019s Hospital, Harvard Medical School, Boston, Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian M.","family":"Alexander","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology, Dana-Farber\/Brigham and Women\u2019s Cancer Center, Harvard Medical School, Boston, Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ayal A.","family":"Aizer","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology, Dana-Farber\/Brigham and Women\u2019s Cancer Center, Harvard Medical School, Boston, Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"10","reference":[{"issue":"11","key":"coi180127r1","doi-asserted-by":"publisher","first-page":"1511","DOI":"10.1093\/neuonc\/nox077","article-title":"Incidence and prognosis of patients with brain metastases at diagnosis of systemic malignancy: a population-based study.","volume":"19","author":"Cagney","year":"2017","journal-title":"Neuro Oncol"},{"issue":"8","key":"coi180127r2","doi-asserted-by":"publisher","first-page":"494","DOI":"10.1056\/NEJM199002223220802","article-title":"A randomized trial of surgery in the treatment of single metastases to the brain.","volume":"322","author":"Patchell","year":"1990","journal-title":"N Engl J Med"},{"issue":"6","key":"coi180127r3","doi-asserted-by":"publisher","first-page":"583","DOI":"10.1002\/(ISSN)1531-8249","article-title":"Treatment of single brain metastasis: radiotherapy alone or combined with neurosurgery?","volume":"33","author":"Vecht","year":"1993","journal-title":"Ann Neurol"},{"issue":"17","key":"coi180127r4","doi-asserted-by":"publisher","first-page":"1485","DOI":"10.1001\/jama.280.17.1485","article-title":"Postoperative radiotherapy in the treatment of single metastases to the brain: a randomized trial.","volume":"280","author":"Patchell","year":"1998","journal-title":"JAMA"},{"issue":"2","key":"coi180127r5","doi-asserted-by":"publisher","first-page":"134","DOI":"10.1200\/JCO.2010.30.1655","article-title":"Adjuvant whole-brain radiotherapy versus observation after radiosurgery or surgical resection of one to three cerebral metastases: results of the EORTC 22952-26001 study.","volume":"29","author":"Kocher","year":"2011","journal-title":"J Clin Oncol"},{"issue":"1","key":"coi180127r6","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1200\/JCO.2011.41.0639","article-title":"A European Organisation for Research and Treatment of Cancer phase III trial of adjuvant whole-brain radiotherapy versus observation in patients with one to three brain metastases from solid tumors after surgical resection or radiosurgery: quality-of-life results.","volume":"31","author":"Soffietti","year":"2013","journal-title":"J Clin Oncol"},{"issue":"8","key":"coi180127r7","doi-asserted-by":"publisher","first-page":"1049","DOI":"10.1016\/S1470-2045(17)30441-2","article-title":"Postoperative stereotactic radiosurgery compared with whole brain radiotherapy for resected metastatic brain disease (NCCTG N107C\/CEC\u00b73): a multicentre, randomised, controlled, phase 3 trial.","volume":"18","author":"Brown","year":"2017","journal-title":"Lancet Oncol"},{"key":"coi180127r8","article-title":"Effects of surgery with salvage stereotactic radiosurgery versus surgery with whole-brain radiation therapy in patients with one to four brain metastases (jcog0504): a phase III, noninferiority, randomized controlled trial","author":"Kayama","journal-title":"J Clin Oncol"},{"key":"coi180127r9","doi-asserted-by":"publisher","first-page":"75","DOI":"10.3171\/2014.6.GKS14708","article-title":"Stereotactic radiosurgery to the resection bed for intracranial metastases and risk of leptomeningeal carcinomatosis.","volume":"121","author":"Ojerholm","year":"2014","journal-title":"J Neurosurg"},{"issue":"1-2","key":"coi180127r10","doi-asserted-by":"publisher","first-page":"115","DOI":"10.1023\/B:NEON.0000021785.00660.2b","article-title":"Posterior fossa metastases: risk of leptomeningeal disease when treated with stereotactic radiosurgery compared to surgery.","volume":"67","author":"Siomin","year":"2004","journal-title":"J Neurooncol"},{"key":"coi180127r11","doi-asserted-by":"publisher","first-page":"6","DOI":"10.1016\/j.jocn.2017.04.033","article-title":"Leptomeningeal failure in patients with breast cancer receiving stereotactic radiosurgery for brain metastases.","volume":"43","author":"Wang","year":"2017","journal-title":"J Clin Neurosci"},{"issue":"3","key":"coi180127r12","doi-asserted-by":"publisher","first-page":"537","DOI":"10.1016\/j.ijrobp.2015.11.022","article-title":"Surgical resection of brain metastases and the risk of leptomeningeal recurrence in patients treated with stereotactic radiosurgery.","volume":"94","author":"Johnson","year":"2016","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"coi180127r13","doi-asserted-by":"publisher","first-page":"48","DOI":"10.1016\/j.jocn.2017.12.009","article-title":"Postoperative radiosurgery for the treatment of metastatic brain tumor: evaluation of local failure and leptomeningeal disease.","volume":"49","author":"Foreman","year":"2018","journal-title":"J Clin Neurosci"},{"issue":"2","key":"coi180127r14","doi-asserted-by":"publisher","first-page":"525","DOI":"10.1148\/rg.272065155","article-title":"Patterns of contrast enhancement in the brain and meninges.","volume":"27","author":"Smirniotopoulos","year":"2007","journal-title":"Radiographics"},{"issue":"2","key":"coi180127r15","doi-asserted-by":"publisher","first-page":"436","DOI":"10.1016\/j.ijrobp.2017.09.047","article-title":"Consensus contouring guidelines for postoperative completely resected cavity stereotactic radiosurgery for brain metastases.","volume":"100","author":"Soliman","year":"2018","journal-title":"Int J Radiat Oncol Biol Phys"},{"issue":"1","key":"coi180127r16","doi-asserted-by":"publisher","first-page":"139","DOI":"10.1007\/s11060-017-2497-6","article-title":"Stereotactic radiosurgery for focal leptomeningeal disease in patients with brain metastases.","volume":"134","author":"Wolf","year":"2017","journal-title":"J Neurooncol"},{"issue":"7","key":"coi180127r17","doi-asserted-by":"publisher","first-page":"476","DOI":"10.1056\/NEJM199908123410703","article-title":"Prophylactic cranial irradiation for patients with small-cell lung cancer in complete remission.","volume":"341","author":"Aup\u00e9rin","year":"1999","journal-title":"N Engl J Med"},{"issue":"2","key":"coi180127r18","doi-asserted-by":"publisher","first-page":"217","DOI":"10.1016\/j.radonc.2016.10.005","article-title":"Stereotactic radiotherapy of the tumor bed compared to whole brain radiotherapy after surgery of single brain metastasis: results from a randomized trial.","volume":"121","author":"Kepka","year":"2016","journal-title":"Radiother Oncol"},{"issue":"8","key":"coi180127r19","doi-asserted-by":"publisher","first-page":"1123","DOI":"10.1001\/jamaoncol.2017.3993","article-title":"Immunotherapy and symptomatic radiation necrosis in patients with brain metastases treated with stereotactic radiation.","volume":"4","author":"Martin","year":"2018","journal-title":"JAMA Oncol"},{"issue":"4","key":"coi180127r20","doi-asserted-by":"publisher","first-page":"180","DOI":"10.1097\/01.nrl.0000080951.78533.c4","article-title":"Cerebral radiation necrosis.","volume":"9","author":"Giglio","year":"2003","journal-title":"Neurologist"}],"container-title":["JAMA Oncology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/\/jamaoncology\/article-pdf\/5\/5\/703\/17575163\/jamaoncology_cagney_2019_oi_180127.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,9]],"date-time":"2019-05-09T12:53:48Z","timestamp":1557406428000},"score":1,"resource":{"primary":{"URL":"http:\/\/oncology.jamanetwork.com\/article.aspx?doi=10.1001\/jamaoncol.2018.7204"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,5,1]]},"references-count":20,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2019,5,1]]}},"URL":"https:\/\/doi.org\/10.1001\/jamaoncol.2018.7204","relation":{},"ISSN":["2374-2437"],"issn-type":[{"value":"2374-2437","type":"print"}],"subject":[],"published":{"date-parts":[[2019,5,1]]}}}