{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T00:22:25Z","timestamp":1790295745422,"version":"4.1.0"},"reference-count":37,"publisher":"American Medical Association (AMA)","issue":"11","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JAMA Otolaryngol Head Neck Surg"],"published-print":{"date-parts":[[2018,11,1]]},"DOI":"10.1001\/jamaoto.2018.1791","type":"journal-article","created":{"date-parts":[[2018,9,7]],"date-time":"2018-09-07T16:10:29Z","timestamp":1536336629000},"page":"1066","source":"Crossref","is-referenced-by-count":32,"title":["Symptom Burden Associated With Late Lower Cranial Neuropathy in Long-term Oropharyngeal Cancer Survivors"],"prefix":"10.1001","volume":"144","author":[{"given":"Puja","family":"Aggarwal","sequence":"first","affiliation":[{"name":"Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston"},{"name":"Division of Epidemiology & Disease Control, School of Public Health, The University of Texas, Houston"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jhankruti S.","family":"Zaveri","sequence":"additional","affiliation":[{"name":"Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryan P.","family":"Goepfert","sequence":"additional","affiliation":[{"name":"Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiuling","family":"Shi","sequence":"additional","affiliation":[{"name":"Department of Symptom Research, The University of Texas MD Anderson Cancer Center, Houston"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xianglin L.","family":"Du","sequence":"additional","affiliation":[{"name":"Division of Epidemiology & Disease Control, School of Public Health, The University of Texas, Houston"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Swartz","sequence":"additional","affiliation":[{"name":"Division of Epidemiology & Disease Control, School of Public Health, The University of Texas, Houston"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G. Brandon","family":"Gunn","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen Y.","family":"Lai","sequence":"additional","affiliation":[{"name":"Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C. David","family":"Fuller","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ehab Y.","family":"Hanna","sequence":"additional","affiliation":[{"name":"Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David I.","family":"Rosenthal","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan S.","family":"Lewin","sequence":"additional","affiliation":[{"name":"Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linda B.","family":"Piller","sequence":"additional","affiliation":[{"name":"Division of Epidemiology & Disease Control, School of Public Health, The University of Texas, Houston"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katherine A.","family":"Hutcheson","sequence":"additional","affiliation":[{"name":"Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"10","reference":[{"issue":"32","key":"ooi180058r1","doi-asserted-by":"publisher","first-page":"4294","DOI":"10.1200\/JCO.2011.36.4596","article-title":"Human papillomavirus and rising oropharyngeal cancer incidence in the United States.","volume":"29","author":"Chaturvedi","year":"2011","journal-title":"J Clin Oncol"},{"issue":"1","key":"ooi180058r2","doi-asserted-by":"publisher","first-page":"24","DOI":"10.1056\/NEJMoa0912217","article-title":"Human papillomavirus and survival of patients with oropharyngeal cancer.","volume":"363","author":"Ang","year":"2010","journal-title":"N Engl J Med"},{"issue":"3","key":"ooi180058r3","doi-asserted-by":"publisher","first-page":"336","DOI":"10.1002\/(ISSN)1097-0215","article-title":"Human papillomavirus infection as a prognostic factor in carcinomas of the oral cavity and oropharynx.","volume":"104","author":"Ritchie","year":"2003","journal-title":"Int J Cancer"},{"issue":"12","key":"ooi180058r4","doi-asserted-by":"publisher","first-page":"2656","DOI":"10.1002\/(ISSN)1097-0215","article-title":"Marked differences in survival rate between smokers and nonsmokers with HPV 16\u2013associated tonsillar carcinomas.","volume":"122","author":"Hafkamp","year":"2008","journal-title":"Int J Cancer"},{"issue":"5","key":"ooi180058r5","doi-asserted-by":"publisher","first-page":"1207","DOI":"10.1002\/lary.v123.5","article-title":"Delayed lower cranial neuropathies following primary radiotherapy for oropharyngeal squamous cell carcinoma.","volume":"123","author":"Huang","year":"2013","journal-title":"Laryngoscope"},{"issue":"8","key":"ooi180058r6","doi-asserted-by":"publisher","first-page":"1516","DOI":"10.1002\/hed.v39.8","article-title":"Delayed lower cranial neuropathy after oropharyngeal intensity-modulated radiotherapy: a cohort analysis and literature review.","volume":"39","author":"Hutcheson","year":"2017","journal-title":"Head Neck"},{"issue":"4","key":"ooi180058r7","doi-asserted-by":"publisher","first-page":"E56","DOI":"10.1002\/hed.v37.4","article-title":"Late radiation-associated dysphagia with lower cranial neuropathy in long-term oropharyngeal cancer survivors: video case reports.","volume":"37","author":"Hutcheson","year":"2015","journal-title":"Head Neck"},{"issue":"2","key":"ooi180058r8","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1044\/sasd22.2.61","article-title":"Late radiation-associated dysphagia (RAD) in head and neck cancer survivors.","volume":"22","author":"Hutcheson","year":"2013","journal-title":"Perspect Swal Swal Dis (Dysph)"},{"issue":"10","key":"ooi180058r9","doi-asserted-by":"publisher","first-page":"1051","DOI":"10.1016\/j.diii.2013.06.013","article-title":"The lower cranial nerves: IX, X, XI, XII.","volume":"94","author":"Sarrazin","year":"2013","journal-title":"Diagn Interv Imaging"},{"issue":"37","key":"ooi180058r10","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1093\/jncimonographs\/lgm005","article-title":"Symptom burden: multiple symptoms and their impact as patient-reported outcomes.","author":"Cleeland","year":"2007","journal-title":"J Natl Cancer Inst Monogr"},{"issue":"29","key":"ooi180058r12","doi-asserted-by":"publisher","first-page":"3314","DOI":"10.1200\/JCO.2015.61.3836","article-title":"Advances in supportive care for late effects of head and neck cancer.","volume":"33","author":"Murphy","year":"2015","journal-title":"J Clin Oncol"},{"issue":"6","key":"ooi180058r13","doi-asserted-by":"publisher","first-page":"764","DOI":"10.1001\/archotol.130.6.764","article-title":"Disability in patients with head and neck cancer.","volume":"130","author":"Taylor","year":"2004","journal-title":"Arch Otolaryngol Head Neck Surg"},{"issue":"11","key":"ooi180058r14","doi-asserted-by":"publisher","first-page":"2151","DOI":"10.1002\/hed.v39.11","article-title":"Symptom burden as a driver of decisional regret in long-term oropharyngeal carcinoma survivors.","volume":"39","author":"Goepfert","year":"2017","journal-title":"Head Neck"},{"key":"ooi180058r15","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1186\/1748-717X-8-21","article-title":"Outcomes and patterns of care of patients with locally advanced oropharyngeal carcinoma treated in the early 21st century.","volume":"8","author":"Garden","year":"2013","journal-title":"Radiat Oncol"},{"issue":"6","key":"ooi180058r16","doi-asserted-by":"publisher","first-page":"665","DOI":"10.6004\/jnccn.2011.0055","article-title":"The epidemic of HPV-associated oropharyngeal cancer is here: is it time to change our treatment paradigms?","volume":"9","author":"Sturgis","year":"2011","journal-title":"J Natl Compr Canc Netw"},{"issue":"6","key":"ooi180058r17","doi-asserted-by":"publisher","first-page":"886","DOI":"10.1002\/hed.24195","article-title":"Impact of selective neck dissection on chronic dysphagia after chemo-intensity-modulated radiotherapy for oropharyngeal carcinoma.","volume":"38","author":"Hutcheson","year":"2016","journal-title":"Head Neck"},{"issue":"1","key":"ooi180058r18","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1002\/hed.v34.1","article-title":"Voice, swallowing, and quality of life after total laryngectomy: results of the West of Scotland laryngectomy audit.","volume":"34","author":"Robertson","year":"2012","journal-title":"Head Neck"},{"issue":"10","key":"ooi180058r19","doi-asserted-by":"crossref","first-page":"1490","DOI":"10.1002\/hed.23181","article-title":"High symptom burden prior to radiation therapy for head and neck cancer: a patient-reported outcomes study.","volume":"35","author":"Gunn","year":"2013","journal-title":"Head Neck"},{"issue":"10","key":"ooi180058r20","doi-asserted-by":"publisher","first-page":"923","DOI":"10.1002\/(ISSN)1097-0347","article-title":"Measuring head and neck cancer symptom burden: the development and validation of the M. D. Anderson Symptom Inventory, Head and Neck module.","volume":"29","author":"Rosenthal","year":"2007","journal-title":"Head Neck"},{"issue":"5","key":"ooi180058r21","doi-asserted-by":"publisher","first-page":"1355","DOI":"10.1016\/j.ijrobp.2008.02.072","article-title":"The M. D. Anderson Symptom Inventory-Head and Neck module, a patient-reported outcome instrument, accurately predicts the severity of radiation-induced mucositis.","volume":"72","author":"Rosenthal","year":"2008","journal-title":"Int J Radiat Oncol Biol Phys"},{"issue":"3","key":"ooi180058r22","doi-asserted-by":"publisher","first-page":"425","DOI":"10.1002\/cncr.28434","article-title":"Prevalence and characteristics of moderate to severe fatigue: a multicenter study in cancer patients and survivors.","volume":"120","author":"Wang","year":"2014","journal-title":"Cancer"},{"issue":"9","key":"ooi180058r24","doi-asserted-by":"publisher","first-page":"2331","DOI":"10.1007\/s11136-013-0380-2","article-title":"Using group-based trajectory modeling to examine heterogeneity of symptom burden in patients with head and neck cancer undergoing aggressive non-surgical therapy.","volume":"22","author":"Shi","year":"2013","journal-title":"Qual Life Res"},{"issue":"4","key":"ooi180058r25","doi-asserted-by":"publisher","first-page":"1107","DOI":"10.1016\/j.ijrobp.2016.02.044","article-title":"Intensity modulated proton therapy versus intensity modulated photon radiation therapy for oropharyngeal cancer: first comparative results of patient-reported outcomes.","volume":"95","author":"Sio","year":"2016","journal-title":"Int J Radiat Oncol Biol Phys"},{"issue":"1","key":"ooi180058r26","doi-asserted-by":"publisher","first-page":"150","DOI":"10.1186\/s13014-017-0878-9","article-title":"Long-term patient reported outcomes following radiation therapy for oropharyngeal cancer: cross-sectional assessment of a prospective symptom survey in patients =65 years old.","volume":"12","author":"Eraj","year":"2017","journal-title":"Radiat Oncol"},{"key":"ooi180058r27","doi-asserted-by":"publisher","first-page":"75","DOI":"10.1016\/j.oraloncology.2017.01.006","article-title":"Symptom burden and dysphagia associated with osteoradionecrosis in long-term oropharynx cancer survivors: a cohort analysis.","volume":"66","author":"Wong","year":"2017","journal-title":"Oral Oncol"},{"issue":"4","key":"ooi180058r28","doi-asserted-by":"publisher","first-page":"619","DOI":"10.1177\/0194599814545746","article-title":"Nomogram for predicting symptom severity during radiation therapy for head and neck cancer.","volume":"151","author":"Sheu","year":"2014","journal-title":"Otolaryngol Head Neck Surg"},{"key":"ooi180058r30","doi-asserted-by":"publisher","first-page":"425","DOI":"10.1177\/014662168801200410","article-title":"Set correlation and contingency tables.","volume":"12","author":"Cohen","year":"1988","journal-title":"Appl Psychol Meas"},{"issue":"4","key":"ooi180058r31","doi-asserted-by":"publisher","first-page":"305","DOI":"10.1016\/j.oraloncology.2014.10.005","article-title":"The role of surgery for HPV-associated head and neck cancer.","volume":"51","author":"Mydlarz","year":"2015","journal-title":"Oral Oncol"},{"issue":"6","key":"ooi180058r32","doi-asserted-by":"publisher","first-page":"687","DOI":"10.1016\/j.ijom.2017.02.1269","article-title":"Changes in health-related quality of life of oral cancer patients treated with curative intent: experience of a developing country.","volume":"46","author":"Doss","year":"2017","journal-title":"Int J Oral Maxillofac Surg"},{"issue":"5","key":"ooi180058r33","doi-asserted-by":"publisher","first-page":"1108","DOI":"10.1002\/lary.25778","article-title":"What is a clinically relevant difference in MDADI scores between groups of head and neck cancer patients?","volume":"126","author":"Hutcheson","year":"2016","journal-title":"Laryngoscope"},{"issue":"23","key":"ooi180058r34","doi-asserted-by":"publisher","first-page":"5793","DOI":"10.1002\/cncr.v118.23","article-title":"Late dysphagia after radiotherapy-based treatment of head and neck cancer.","volume":"118","author":"Hutcheson","year":"2012","journal-title":"Cancer"},{"issue":"8","key":"ooi180058r35","doi-asserted-by":"publisher","first-page":"1033","DOI":"10.1016\/j.ctrv.2012.04.002","article-title":"Swallowing dysfunction in head and neck cancer patients treated by radiotherapy: review and recommendations of the supportive task group of the Italian Association of Radiation Oncology.","volume":"38","author":"Russi","year":"2012","journal-title":"Cancer Treat Rev"},{"issue":"4","key":"ooi180058r36","doi-asserted-by":"publisher","first-page":"266","DOI":"10.1016\/S0749-2081(05)80007-5","article-title":"Anorexia, cachexia, and dysphagia: the symptom experience.","volume":"11","author":"Grant","year":"1995","journal-title":"Semin Oncol Nurs"},{"key":"ooi180058r37","doi-asserted-by":"publisher","first-page":"171","DOI":"10.2147\/TCRM","article-title":"Xerostomia induced by radiotherapy: an overview of the physiopathology, clinical evidence, and management of the oral damage.","volume":"11","author":"Pinna","year":"2015","journal-title":"Ther Clin Risk Manag"},{"key":"ooi180058r29","doi-asserted-by":"crossref","DOI":"10.1002\/9781118548387","volume-title":"Applied Logistic Regression","author":"Hosmer","year":"2013","edition":"3rd ed"},{"key":"ooi180058r11","unstructured":"National Cancer Institute. Cancer Therapy Evaluation Program, Common Toxicity Criteria Manual. https:\/\/ctep.cancer.gov\/protocolDevelopment\/electronic_applications\/docs\/ctcmanual_v4_10-4-99.pdf. Accessed May 31, 2018."},{"key":"ooi180058r23","unstructured":"MD Anderson Cancer Center. User guide. https:\/\/www.mdanderson.org\/documents\/Departments-and-Divisions\/Symptom-Research\/MDASI_userguide.pdf. Accessed August 30, 2017."}],"container-title":["JAMA Otolaryngology\u2013Head &amp; Neck Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/jamanetwork.com\/journals\/jamaotolaryngology\/fullarticle\/2698897","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,7,10]],"date-time":"2024-07-10T02:29:07Z","timestamp":1720578547000},"score":1,"resource":{"primary":{"URL":"http:\/\/archotol.jamanetwork.com\/article.aspx?doi=10.1001\/jamaoto.2018.1791"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,11,1]]},"references-count":37,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2018,11,1]]}},"URL":"https:\/\/doi.org\/10.1001\/jamaoto.2018.1791","relation":{},"ISSN":["2168-6181"],"issn-type":[{"value":"2168-6181","type":"print"}],"subject":[],"published":{"date-parts":[[2018,11,1]]}}}