{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T20:23:29Z","timestamp":1791491009977,"version":"4.3.4"},"reference-count":40,"publisher":"American Medical Association (AMA)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JAMA Otolaryngol Head Neck Surg"],"published-print":{"date-parts":[[2023,1,1]]},"abstract":"\n Importance<\/jats:title>\n Turbinate surgery is an effective treatment for allergic rhinitis (AR) refractory to medical treatment. However, the long-term outcomes of turbinate surgery are still unclear and have not yet been confirmed by a meta-analysis and systematic review of the literature.<\/jats:p>\n <\/jats:sec>\n \n Objective<\/jats:title>\n To investigate the long-term outcomes and safety of turbinate surgery in AR by performing a meta-analysis.<\/jats:p>\n <\/jats:sec>\n \n Data Sources<\/jats:title>\n MEDLINE, Embase, the Cochrane Library, and ClinicalTrials.gov were searched through April 2021.<\/jats:p>\n <\/jats:sec>\n \n Study Selection<\/jats:title>\n Studies that analyzed turbinate surgery alone, had a follow-up period of more than 1 year, examined long-term efficacy of turbinate surgery, used current turbinate surgery methods, and were published in a peer-reviewed journal were included. Full-text reviews were performed by 2 independent reviewers. Conflicts were resolved by a third reviewer.<\/jats:p>\n <\/jats:sec>\n \n Data Extraction and Synthesis<\/jats:title>\n \n Descriptive and quantitative data were extracted; weighted mean difference (WMD) was synthesized under a random-effects model. Heterogeneity was assessed using the\n Q<\/jats:italic>\n statistic and the\n I<\/jats:italic>\n 2<\/jats:sup>\n metric. This study was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-analyses (\n PRISMA<\/jats:ext-link>\n ) reporting guidelines.\n <\/jats:p>\n <\/jats:sec>\n \n Main Outcomes and Measures<\/jats:title>\n The long-term outcomes of turbinate surgery on subjective nasal symptoms and objective parameters.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n Of the 3962 citations retrieved, 18 studies comprising 1411 patients were included. Findings showed significantly decreased symptom scores in nasal obstruction (WMD, 4.60, 95% CI, 3.43-5.76), rhinorrhea (WMD, 3.12; 95% CI, 1.97-4.28), sneezing (WMD, 2.64; 95% CI, 1.74-3.54), itching (WMD, 1.75; 95% CI, 1.20-2.30), and nasal resistance (WMD, 0.16; 95% CI, 0.08-0.24) and a significant increased total nasal volume (WMD, 0.96; 95% CI, 0.73-1.19). There was no significant difference in the occurrence of any complication. More than 1 year after surgery, the improvements in nasal obstruction (WMD, 5.18; 95% CI, 3.00-7.37), rhinorrhea (WMD, 3.57; 95% CI, 1.78-5.37), and sneezing (WMD, 2.95; 95% CI, 1.58-4.32) were maintained.<\/jats:p>\n <\/jats:sec>\n \n Conclusions and Relevance<\/jats:title>\n In this systematic review and meta-analysis, turbinate surgery was associated with positive outcomes in AR and maintained the association during long-term follow-up. The rate of complications is also low. These findings can guide the preoperative counseling of patients with AR being considered for turbinate surgery.<\/jats:p>\n <\/jats:sec>","DOI":"10.1001\/jamaoto.2022.3567","type":"journal-article","created":{"date-parts":[[2022,11,17]],"date-time":"2022-11-17T11:01:01Z","timestamp":1668682861000},"page":"15","source":"Crossref","is-referenced-by-count":27,"title":["Long-term Outcomes of Turbinate Surgery in Patients With Allergic Rhinitis"],"prefix":"10.1001","volume":"149","author":[{"given":"Sang Chul","family":"Park","sequence":"first","affiliation":[{"name":"Department of Otorhinolaryngology\u2013Head and Neck Surgery, Kangnam Sacred Heart Hospital, Hallym University College of Medicine, Seoul, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Do Hyun","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of 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