{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T08:29:14Z","timestamp":1791016154264,"version":"4.1.0"},"reference-count":46,"publisher":"American Medical Association (AMA)","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JAMA Pediatr"],"DOI":"10.1001\/jamapediatrics.2020.6364","type":"journal-article","created":{"date-parts":[[2021,4,12]],"date-time":"2021-04-12T17:58:03Z","timestamp":1618250283000},"source":"Crossref","is-referenced-by-count":66,"title":["Infant Mortality Associated With Prenatal Opioid Exposure"],"prefix":"10.1001","author":[{"given":"JoAnna K.","family":"Leyenaar","sequence":"first","affiliation":[{"name":"Department of Pediatrics, Children's Hospital at Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire"},{"name":"The Dartmouth Institute for Health Policy & Clinical Practice, Geisel School of Medicine at Dartmouth College, Hanover, New Hampshire"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew P.","family":"Schaefer","sequence":"additional","affiliation":[{"name":"The Dartmouth Institute for Health Policy & Clinical Practice, Geisel School of Medicine at Dartmouth College, Hanover, New Hampshire"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jared R.","family":"Wasserman","sequence":"additional","affiliation":[{"name":"The Dartmouth Institute for Health Policy & Clinical Practice, Geisel School of Medicine at Dartmouth College, Hanover, New Hampshire"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erika L.","family":"Moen","sequence":"additional","affiliation":[{"name":"The Dartmouth Institute for Health Policy & Clinical Practice, Geisel School of Medicine at Dartmouth College, Hanover, New Hampshire"},{"name":"Department of Biomedical Data Science, Geisel School of Medicine at Dartmouth College, Hanover, New Hampshire"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A. James","family":"O\u2019Malley","sequence":"additional","affiliation":[{"name":"The Dartmouth Institute for Health Policy & Clinical Practice, Geisel School of Medicine at Dartmouth College, Hanover, New Hampshire"},{"name":"Department of Biomedical Data Science, Geisel School of Medicine at Dartmouth College, Hanover, New Hampshire"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David C.","family":"Goodman","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Children's Hospital at Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire"},{"name":"The Dartmouth Institute for Health Policy & Clinical Practice, Geisel School of Medicine at Dartmouth College, Hanover, New Hampshire"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"10","published-online":{"date-parts":[[2021,4,12]]},"reference":[{"issue":"1","key":"poi200100r2","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1097\/AOG.0000000000002054","article-title":"Opioid use in pregnancy, neonatal abstinence syndrome, and childhood outcomes: executive summary of a joint workshop by the Eunice Kennedy Shriver National Institute of Child Health and Human Development, American College of Obstetricians and Gynecologists, American Academy of Pediatrics, Society for Maternal-Fetal Medicine, Centers for Disease Control and Prevention, and the March of Dimes Foundation.","volume":"130","author":"Reddy","year":"2017","journal-title":"Obstet Gynecol"},{"issue":"2","key":"poi200100r3","doi-asserted-by":"publisher","first-page":"353","DOI":"10.1016\/j.pcl.2018.12.006","article-title":"Neonatal abstinence syndrome.","volume":"66","author":"Jansson","year":"2019","journal-title":"Pediatr Clin North Am"},{"issue":"2","key":"poi200100r4","doi-asserted-by":"publisher","first-page":"e81","DOI":"10.1097\/AOG.0000000000002235","article-title":"Opioid use and opioid use disorder in pregnancy: Committee Opinion No. 711. American College of Obstetricians and Gynecologists.","volume":"130","year":"2017","journal-title":"Obstet Gynecol"},{"issue":"4","key":"poi200100r5","doi-asserted-by":"crossref","DOI":"10.1542\/peds.2017-3520","article-title":"Incidence and costs of neonatal abstinence syndrome among infants with Medicaid: 2004-2014.","volume":"141","author":"Winkelman","year":"2018","journal-title":"Pediatrics"},{"issue":"2","key":"poi200100r6","doi-asserted-by":"publisher","first-page":"200","DOI":"10.1001\/jamapediatrics.2019.4791","article-title":"Neonatal abstinence syndrome incidence and health care costs in the United States, 2016.","volume":"174","author":"Strahan","year":"2020","journal-title":"JAMA Pediatr"},{"issue":"8","key":"poi200100r7","doi-asserted-by":"publisher","first-page":"650","DOI":"10.1038\/jp.2015.36","article-title":"Increasing incidence and geographic distribution of neonatal abstinence syndrome: United States 2009 to 2012.","volume":"35","author":"Patrick","year":"2015","journal-title":"J Perinatol"},{"issue":"6","key":"poi200100r8","doi-asserted-by":"crossref","DOI":"10.1542\/peds.2015-2929","article-title":"Rooming-in to treat neonatal abstinence syndrome: improved family-centered care at lower cost.","volume":"137","author":"Holmes","year":"2016","journal-title":"Pediatrics"},{"issue":"6","key":"poi200100r9","doi-asserted-by":"publisher","first-page":"441","DOI":"10.1097\/DBP.0000000000000679","article-title":"Early intervention referral and enrollment among infants with neonatal abstinence syndrome.","volume":"40","author":"Peacock-Chambers","year":"2019","journal-title":"J Dev Behav Pediatr"},{"issue":"4","key":"poi200100r10","doi-asserted-by":"crossref","DOI":"10.1542\/peds.2017-0900","article-title":"Ohio perinatal quality collaborative improves care of neonatal narcotic abstinence syndrome.","volume":"141","author":"Walsh","year":"2018","journal-title":"Pediatrics"},{"issue":"8","key":"poi200100r11","doi-asserted-by":"publisher","first-page":"1114","DOI":"10.1038\/s41372-018-0109-8","article-title":"Quality improvement initiative to improve inpatient outcomes for neonatal abstinence syndrome.","volume":"38","author":"Wachman","year":"2018","journal-title":"J Perinatol"},{"issue":"7","key":"poi200100r12","doi-asserted-by":"crossref","DOI":"10.1001\/jamanetworkopen.2019.7025","article-title":"Cognitive and motor outcomes of children with prenatal opioid exposure: a systematic review and meta-analysis.","volume":"2","author":"Yeoh","year":"2019","journal-title":"JAMA Netw Open"},{"issue":"3","key":"poi200100r13","doi-asserted-by":"crossref","DOI":"10.1542\/peds.2019-0128","article-title":"Prenatal opioid exposure: neurodevelopmental consequences and future research priorities.","volume":"144","author":"Conradt","year":"2019","journal-title":"Pediatrics"},{"issue":"5","key":"poi200100r14","doi-asserted-by":"publisher","first-page":"277","DOI":"10.1891\/0730-0832.35.5.277","article-title":"Long-term outcomes of infants with neonatal abstinence syndrome.","volume":"35","author":"Maguire","year":"2016","journal-title":"Neonatal Netw"},{"issue":"10","key":"poi200100r15","doi-asserted-by":"publisher","first-page":"1124","DOI":"10.1038\/jp.2017.106","article-title":"Neonatal abstinence syndrome and early childhood morbidity and mortality in Washington state: a retrospective cohort study.","volume":"37","author":"Witt","year":"2017","journal-title":"J Perinatol"},{"issue":"3","key":"poi200100r16","doi-asserted-by":"publisher","first-page":"157","DOI":"10.1016\/j.jogc.2016.11.009","article-title":"Infants born to opioid-dependent women in Ontario, 2002-2014.","volume":"39","author":"Brogly","year":"2017","journal-title":"J Obstet Gynaecol Can"},{"issue":"3","key":"poi200100r17","doi-asserted-by":"publisher","first-page":"127","DOI":"10.1111\/jpc.2007.43.issue-3","article-title":"Short-term outcomes of infants of substance-using mothers admitted to neonatal intensive care units in New South Wales and the Australian Capital Territory.","volume":"43","author":"Abdel-Latif","year":"2007","journal-title":"J Paediatr Child Health"},{"issue":"8","key":"poi200100r20","doi-asserted-by":"publisher","first-page":"747","DOI":"10.1001\/jamapediatrics.2017.0745","article-title":"Trends in receipt of buprenorphine and naltrexone for opioid use disorder among adolescents and young adults, 2001-2014.","volume":"171","author":"Hadland","year":"2017","journal-title":"JAMA Pediatr"},{"issue":"11","key":"poi200100r21","doi-asserted-by":"publisher","first-page":"1029","DOI":"10.1001\/jamapediatrics.2018.2143","article-title":"Receipt of timely addiction treatment and association of early medication treatment with retention in care among youths with opioid use disorder.","volume":"172","author":"Hadland","year":"2018","journal-title":"JAMA Pediatr"},{"issue":"1","key":"poi200100r22","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1542\/peds.2017-4183","article-title":"Positive predictive value of administrative data for neonatal abstinence syndrome.","volume":"143","author":"Maalouf","year":"2019","journal-title":"Pediatrics"},{"issue":"8","key":"poi200100r24","doi-asserted-by":"publisher","first-page":"948","DOI":"10.1016\/j.acap.2019.05.132","article-title":"Trends in pediatric emergency department visits for mental health conditions and disposition by presence of a psychiatric unit.","volume":"19","author":"Cutler","year":"2019","journal-title":"Acad Pediatr"},{"issue":"13","key":"poi200100r25","doi-asserted-by":"publisher","first-page":"1748","DOI":"10.1111\/bjo.2015.122.issue-13","article-title":"Validation of an obstetric comorbidity index in an external population.","volume":"122","author":"Metcalfe","year":"2015","journal-title":"BJOG"},{"issue":"5","key":"poi200100r26","doi-asserted-by":"publisher","first-page":"957","DOI":"10.1097\/AOG.0b013e3182a603bb","article-title":"Development of a comorbidity index for use in obstetric patients.","volume":"122","author":"Bateman","year":"2013","journal-title":"Obstet Gynecol"},{"issue":"2S","key":"poi200100r27","doi-asserted-by":"publisher","first-page":"S630","DOI":"10.1016\/j.ajog.2018.01.011","article-title":"The INTERGROWTH-21st fetal growth standards: toward the global integration of pregnancy and pediatric care.","volume":"218","author":"Papageorghiou","year":"2018","journal-title":"Am J Obstet Gynecol"},{"issue":"2","key":"poi200100r29","doi-asserted-by":"publisher","first-page":"167","DOI":"10.1001\/jamapsychiatry.2017.3644","article-title":"Association between methylphenidate and amphetamine use in pregnancy and risk of congenital malformations: a cohort study from the International Pregnancy Safety Study Consortium.","volume":"75","author":"Huybrechts","year":"2018","journal-title":"JAMA Psychiatry"},{"key":"poi200100r30","doi-asserted-by":"publisher","first-page":"h1035","DOI":"10.1136\/bmj.h1035","article-title":"Statins and congenital malformations: cohort study.","volume":"350","author":"Bateman","year":"2015","journal-title":"BMJ"},{"issue":"1","key":"poi200100r31","doi-asserted-by":"crossref","DOI":"10.1542\/peds.2019-1637","article-title":"Distinct populations of sudden unexpected infant death based on age.","volume":"145","author":"Lavista Ferres","year":"2020","journal-title":"Pediatrics"},{"issue":"6","key":"poi200100r32","doi-asserted-by":"publisher","first-page":"632","DOI":"10.1177\/003335491513000613","article-title":"Infant mortality: development of a proposed update to the Dollfus classification of infant deaths.","volume":"130","author":"Nakamura","year":"2015","journal-title":"Public Health Rep"},{"issue":"18","key":"poi200100r33","doi-asserted-by":"publisher","first-page":"1934","DOI":"10.1001\/jama.2012.3951","article-title":"Neonatal abstinence syndrome and associated health care expenditures: United States, 2000-2009.","volume":"307","author":"Patrick","year":"2012","journal-title":"JAMA"},{"issue":"3","key":"poi200100r34","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0018174","article-title":"Weight trimming and propensity score weighting.","volume":"6","author":"Lee","year":"2011","journal-title":"PLoS One"},{"issue":"5","key":"poi200100r35","doi-asserted-by":"publisher","first-page":"551","DOI":"10.1111\/j.1465-3362.2010.00176.x","article-title":"Infant mortality among women on a methadone program during pregnancy.","volume":"29","author":"Burns","year":"2010","journal-title":"Drug Alcohol Rev"},{"key":"poi200100r36","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1111\/nyas.1988.533.issue-1","article-title":"Risk factors for SIDS. results of the National Institute of Child Health and Human Development SIDS Cooperative Epidemiological Study.","volume":"533","author":"Hoffman","year":"1988","journal-title":"Ann N Y Acad Sci"},{"issue":"6","key":"poi200100r37","doi-asserted-by":"publisher","first-page":"909","DOI":"10.1016\/S0022-3476(05)80133-7","article-title":"Association between prenatal cocaine exposure and sudden infant death syndrome.","volume":"117","author":"Durand","year":"1990","journal-title":"J Pediatr"},{"issue":"1","key":"poi200100r38","doi-asserted-by":"publisher","first-page":"120","DOI":"10.1016\/S0022-3476(05)81554-9","article-title":"Relationship of maternal substance abuse to subsequent sudden infant death syndrome in offspring.","volume":"123","author":"Kandall","year":"1993","journal-title":"J Pediatr"},{"issue":"2","key":"poi200100r39","doi-asserted-by":"publisher","first-page":"161","DOI":"10.1016\/j.siny.2019.01.012","article-title":"After NAS.","volume":"24","author":"Oei","year":"2019","journal-title":"Semin Fetal Neonatal Med"},{"issue":"5","key":"poi200100r40","doi-asserted-by":"publisher","first-page":"869","DOI":"10.1016\/S0022-3476(73)80086-1","article-title":"Heroin induction of lung maturation and growth retardation in fetal rabbits.","volume":"82","author":"Taeusch","year":"1973","journal-title":"J Pediatr"},{"issue":"1","key":"poi200100r41","doi-asserted-by":"publisher","first-page":"60","DOI":"10.1097\/JAN.0000000000000325","article-title":"Transition home: safe plan of care for infants with a history of neonatal abstinence syndrome.","volume":"31","author":"Bordelon","year":"2020","journal-title":"J Addict Nurs"},{"issue":"2","key":"poi200100r42","doi-asserted-by":"publisher","first-page":"466","DOI":"10.1097\/AOG.0000000000002734","article-title":"Fatal and nonfatal overdose among pregnant and postpartum women in Massachusetts.","volume":"132","author":"Schiff","year":"2018","journal-title":"Obstet Gynecol"},{"key":"poi200100r43","doi-asserted-by":"publisher","first-page":"225","DOI":"10.1016\/j.drugalcdep.2015.02.012","article-title":"Medication assisted treatment discontinuation in pregnant and postpartum women with opioid use disorder.","volume":"149","author":"Wilder","year":"2015","journal-title":"Drug Alcohol Depend"},{"issue":"6","key":"poi200100r44","doi-asserted-by":"publisher","first-page":"841","DOI":"10.1007\/s10995-018-2457-6","article-title":"Mental health of mothers of infants with neonatal abstinence syndrome and prenatal opioid exposure.","volume":"22","author":"Faherty","year":"2018","journal-title":"Matern Child Health J"},{"issue":"4","key":"poi200100r45","doi-asserted-by":"publisher","first-page":"295","DOI":"10.1016\/j.ajog.2019.02.056","article-title":"Maternal self-harm deaths: an unrecognized and preventable outcome.","volume":"221","author":"Mangla","year":"2019","journal-title":"Am J Obstet Gynecol"},{"key":"poi200100r1","unstructured":"Substance Abuse and Mental Health Services Administration. Key substance use and mental health National Survey on Drug Use and Health (HHS publication No. PEP20-07-01-001, NSDUH series H-55). Published 2020. Accessed February 4, 2021. https:\/\/www.samhsa.gov\/data\/"},{"key":"poi200100r18","unstructured":"Texas Health and Human Services. 2010 Natality. Accessed May 14, 2020. https:\/\/www.dshs.state.tx.us\/chs\/vstat\/vs10\/nnatal.shtm"},{"key":"poi200100r19","unstructured":"Heslin? KC, Elixhauser? A, Steiner? CA. Hospitalizations involving mental and substance use disorders among adults, 2012. Statistical brief #191. Agency for Healthcare Research and Quality. Published June 2015. Accessed February 4, 2021. https:\/\/www.hcup-us.ahrq.gov\/reports\/statbriefs\/sb191-Hospitalization-Mental-Substance-Use-Disorders-2012.jsp?"},{"key":"poi200100r23","unstructured":"Children\u2019s Hospital Association. Mental health disorder codes. Updated September 10, 2019. Accessed September 26, 2019. https:\/\/www.childrenshospitals.org\/Research-and-Data\/Pediatric-Data-and-Trends\/2019\/Mental-Health-Disorder-Codes"},{"key":"poi200100r28","unstructured":"Global Health Network. INTERGROWTH-21st. Standards and tools. Accessed March 21, 2020. https:\/\/intergrowth21.tghn.org\/standards-tools\/"},{"key":"poi200100r46","unstructured":"Medicaid.gov. State overviews. Updated October 2020. Accessed August 11, 2020. https:\/\/www.medicaid.gov\/state-overviews\/index.html"}],"container-title":["JAMA Pediatrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/jamanetwork.com\/journals\/jamapediatrics\/articlepdf\/2778433\/jamapediatrics_leyenaar_2021_oi_200100_1617998989.00987.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,4,12]],"date-time":"2021-04-12T17:58:37Z","timestamp":1618250317000},"score":1,"resource":{"primary":{"URL":"https:\/\/jamanetwork.com\/journals\/jamapediatrics\/fullarticle\/2778433"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,4,12]]},"references-count":46,"URL":"https:\/\/doi.org\/10.1001\/jamapediatrics.2020.6364","relation":{},"ISSN":["2168-6203"],"issn-type":[{"value":"2168-6203","type":"print"}],"subject":[],"published":{"date-parts":[[2021,4,12]]}}}