{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T10:28:26Z","timestamp":1787740106104,"version":"build-2784847793"},"reference-count":64,"publisher":"American Medical Association (AMA)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JAMA Pediatr"],"published-print":{"date-parts":[[2023,3,1]]},"abstract":"<jats:sec><jats:title>Importance<\/jats:title><jats:p>Early behavior problems in children with developmental delay (DD) are prevalent and impairing, but service barriers persist. Controlled studies examining telehealth approaches are limited, particularly for children with DD.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>To evaluate the efficacy of a telehealth parenting intervention for behavior problems in young children with DD.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design, Setting, and Participants<\/jats:title><jats:p>A randomized clinical trial was conducted from March 17, 2016, to December 15, 2020, in which children with DD and externalizing behavior problems were recruited from early intervention and randomly assigned to a telehealth parenting intervention or control group and evaluated through a 12-month follow-up. Most children were from ethnic or racial minoritized backgrounds. Over one-half of children were in extreme poverty or low income-need ratio categories.<\/jats:p><\/jats:sec><jats:sec><jats:title>Interventions<\/jats:title><jats:p>Internet-delivered parent-child interaction therapy (iPCIT), which leverages videoconferencing to provide live coaching of home-based caregiver-child interactions. Families received 20 weeks of iPCIT (provided in English or in Spanish) or referrals as usual (RAU).<\/jats:p><\/jats:sec><jats:sec><jats:title>Main Outcomes and Measures<\/jats:title><jats:p>Observational and caregiver-report measures of child and caregiver behaviors and caregiving stress were examined at preintervention, midtreatment, and postintervention and at 6- and 12-month follow-ups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The sample included a total of\u2009150 children (mean [SD] age,\u200936.2 [1.0] months; 111 male children [74%]) and their caregivers with 75 each randomly assigned to iPCIT or RAU groups. Children receiving iPCIT relative to RAU displayed significantly lower levels of externalizing problems (postintervention Cohen <jats:italic>d<\/jats:italic>\u2009=\u20090.48; 6-month Cohen <jats:italic>d<\/jats:italic>\u2009=\u20090.49; 12-month Cohen <jats:italic>d<\/jats:italic>\u2009=\u20090.50) and significantly higher levels of compliance to caregiver direction after treatment. Of those children with data at postintervention, greater clinically significant change was observed at postintervention for children in the iPCIT group (50 [74%]) than for those in the RAU group (30 [42%]), which was maintained at the 6-month but not the 12-month follow-up. iPCIT did not outperform RAU in reducing caregiving stress, but caregivers receiving iPCIT, relative to RAU, showed steeper increases in proportion of observed positive parenting skills (postintervention odds ratio [OR],\u20091.10; 95% CI, 0.53-2.21; 6-month OR, 1.31; 95% CI, 0.61-2.55; 12-month OR,\u20091.64; 95% CI, 0.70-3.07) and sharper decreases in proportion of observed controlling\/critical behaviors (postintervention OR, 1.40; 95% CI, 0.61-1.52; 6-month OR,\u20091.72; 95% CI, 0.58-1.46; 12-month OR,\u20092.23; 95% CI, 0.53-1.37). After treatment, iPCIT caregivers also self-reported steeper decreases in harsh and inconsistent discipline than did than RAU caregivers (postintervention Cohen <jats:italic>d<\/jats:italic>\u2009=\u20090.24; 6-month Cohen <jats:italic>d<\/jats:italic>\u2009=\u20090.26; 12-month Cohen <jats:italic>d<\/jats:italic>\u2009=\u20090.27).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions and Relevance<\/jats:title><jats:p>Results of this randomized clinical trial provide evidence that a telehealth-delivered parenting intervention with real-time therapist coaching led to significant and maintained improvements for young children with DD and their caregivers. Findings underscore the promise of telehealth formats for expanding scope and reach of care for underserved families.<\/jats:p><\/jats:sec><jats:sec><jats:title>Trial Registration<\/jats:title><jats:p>ClinicalTrials.gov Identifier: <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"https:\/\/clinicaltrials.gov\/ct2\/show\/NCT03260816\">NCT03260816<\/jats:ext-link><\/jats:p><\/jats:sec>","DOI":"10.1001\/jamapediatrics.2022.5204","type":"journal-article","created":{"date-parts":[[2023,1,9]],"date-time":"2023-01-09T16:04:34Z","timestamp":1673280274000},"page":"231","source":"Crossref","is-referenced-by-count":40,"title":["Telehealth Treatment of Behavior Problems in Young Children With Developmental Delay"],"prefix":"10.1001","volume":"177","author":[{"given":"Daniel M.","family":"Bagner","sequence":"first","affiliation":[{"name":"Department of Psychology, Florida International University, Miami"},{"name":"Center for Children and Families, 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