{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T14:10:16Z","timestamp":1786975816608,"version":"build-2736575974"},"reference-count":58,"publisher":"American Medical Association (AMA)","issue":"11","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JAMA Pediatr"],"published-print":{"date-parts":[[2023,11,1]]},"abstract":"\n Importance<\/jats:title>\n Neonatal hypoglycemia is common, occurring in up to 50% of infants at risk for hypoglycemia (infant of diabetic mother [IDM], small for gestational age [SGA], large for gestational age [LGA], and preterm) and is associated with long-term neurodevelopmental impairment. Guidelines recommend screening infants at risk of hypoglycemia. The proportion of infants who require screening for neonatal hypoglycemia is unknown.<\/jats:p>\n <\/jats:sec>\n \n Objective<\/jats:title>\n To determine the proportion of infants eligible for neonatal hypoglycemia screening using criteria from the highest-scoring critically appraised clinical guideline.<\/jats:p>\n <\/jats:sec>\n \n Design, Setting, and Participants<\/jats:title>\n This systematic review of the literature was conducted to identify clinical practice guidelines for neonatal hypoglycemia and took place at a tertiary maternity hospital in Auckland, New Zealand. Eligible guidelines were critically appraised using the Appraisal of Guidelines for Research and Evaluation II tool. Using screening criteria extracted from the highest-scoring guideline, the proportion of infants eligible for neonatal hypoglycemia screening was determined in a retrospective observational cohort study of infants born January 1, 2004, to December 31, 2018. Data were analyzed by logistic regression. Infant participants were included if gestational age was 35 weeks or more, birth weight was 2000 g or more, and they were not admitted to a neonatal intensive care unit less than 1 hour after birth. The data were analyzed from November 2022 through February 2023. A total of 101\u202f372 infants met the inclusion criteria.<\/jats:p>\n <\/jats:sec>\n \n Exposure<\/jats:title>\n Risk factors for neonatal hypoglycemia.<\/jats:p>\n <\/jats:sec>\n \n Main Outcome<\/jats:title>\n Proportion of infants eligible for neonatal hypoglycemia screening.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n The study team screened 2366 abstracts and 18 guidelines met inclusion criteria for appraisal. There was variability in the assessed quality of guidelines and a lack of consensus between screening criteria. The highest-scoring guideline defined screening criteria as: IDM, preterm (less than 37 weeks\u2019 gestation), SGA (less than 10th percentile), birth weight of less than 2500 g or more than 4500 g, LGA (more than 90th percentile), or gestational age more than 42 weeks. A total of 101 372 infants met criteria for inclusion in the cohort study; median (IQR) gestational age was 39 (38-40) weeks and 51% were male. The overall proportion of infants eligible for screening was 26.3%. There was an increase in the proportion of eligible infants from 25.6% to 28.5% over 15 years, which was not statistically significant after adjustment for maternal age, body mass index, ethnicity, and multiple pregnancy (odds ratio, 0.99; 95% CI, 0.93-1.03; change in proportion per year).<\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n A systematic review found that practice guidelines providing recommendations for clinical care of neonatal hypoglycemia were of variable quality with is a lack of consensus regarding definitions for infants at risk for hypoglycemia. In the cohort study, one-quarter of infants were eligible for hypoglycemia screening. Further research is required to identify which infants may benefit from neonatal hypoglycemia screening.<\/jats:p>\n <\/jats:sec>","DOI":"10.1001\/jamapediatrics.2023.3957","type":"journal-article","created":{"date-parts":[[2023,10,2]],"date-time":"2023-10-02T11:01:10Z","timestamp":1696244470000},"page":"1187","source":"Crossref","is-referenced-by-count":30,"title":["Infants Eligible for Neonatal Hypoglycemia Screening"],"prefix":"10.1001","volume":"177","author":[{"given":"Michelle","family":"O\u2019Brien","sequence":"first","affiliation":[{"name":"Department of Paediatrics, Child and Youth Health, Waipapa Taumata Rau \u2013 The University of Auckland, Auckland, New Zealand"},{"name":"Newborn Services, Te Whatu Ora \u2013 Health New Zealand, Te Toka Tumai, Auckland, New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine","family":"Gilchrist","sequence":"additional","affiliation":[{"name":"Department of Paediatrics, Child and Youth Health, Waipapa Taumata Rau \u2013 The University of Auckland, Auckland, New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lynn","family":"Sadler","sequence":"additional","affiliation":[{"name":"Obstetrics and Gynaecology, Te Whatu Ora \u2013 Health New Zealand, Te Toka Tumai Auckland, New Zealand"},{"name":"Women\u2019s Health, Te Whatu Ora \u2013 Health New Zealand, Te Toka Tumai, Auckland, New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joanne E.","family":"Hegarty","sequence":"additional","affiliation":[{"name":"Newborn Services, Te Whatu Ora \u2013 Health New Zealand, Te Toka Tumai, Auckland, New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jane M.","family":"Alsweiler","sequence":"additional","affiliation":[{"name":"Department of Paediatrics, Child and Youth Health, Waipapa Taumata Rau \u2013 The University of Auckland, Auckland, New Zealand"},{"name":"Newborn Services, Te Whatu Ora \u2013 Health New Zealand, Te Toka Tumai, Auckland, New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"10","reference":[{"issue":"5","key":"poi230059r1","doi-asserted-by":"publisher","first-page":"787","DOI":"10.1016\/j.jpeds.2012.05.022","article-title":"Incidence of neonatal hypoglycemia in babies identified as at risk.","volume":"161","author":"Harris","year":"2012","journal-title":"J Pediatr"},{"key":"poi230059r2","doi-asserted-by":"publisher","first-page":"51","DOI":"10.1016\/j.earlhumdev.2016.12.009","article-title":"An emerging evidence base for the management of neonatal hypoglycaemia.","volume":"104","author":"Harding","year":"2017","journal-title":"Early Hum Dev"},{"issue":"5","key":"poi230059r3","doi-asserted-by":"publisher","first-page":"1141","DOI":"10.1542\/peds.105.5.1141","article-title":"Controversies regarding definition of neonatal hypoglycemia: suggested operational thresholds.","volume":"105","author":"Cornblath","year":"2000","journal-title":"Pediatrics"},{"issue":"12","key":"poi230059r4","doi-asserted-by":"publisher","first-page":"1158","DOI":"10.1001\/jama.2022.0992","article-title":"Association of neonatal hypoglycemia with academic performance in mid-childhood.","volume":"327","author":"Shah","year":"2022","journal-title":"JAMA"},{"issue":"1","key":"poi230059r5","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1186\/s40748-016-0031-z","article-title":"New approaches to management of neonatal hypoglycemia.","volume":"2","author":"Rozance","year":"2016","journal-title":"Matern Health Neonatol Perinatol"},{"issue":"5","key":"poi230059r6","doi-asserted-by":"publisher","first-page":"275","DOI":"10.1016\/j.earlhumdev.2010.05.002","article-title":"Describing hypoglycemia\u2013definition or operational threshold?","volume":"86","author":"Rozance","year":"2010","journal-title":"Early Hum Dev"},{"issue":"1","key":"poi230059r7","doi-asserted-by":"publisher","first-page":"36","DOI":"10.1016\/j.siny.2016.08.007","article-title":"Neonatal hypoglycemia.","volume":"22","author":"Adamkin","year":"2017","journal-title":"Semin Fetal Neonatal Med"},{"issue":"3","key":"poi230059r8","first-page":"261","article-title":"Hypoglycaemia of the newborn: a review.","volume":"75","author":"Williams","year":"1997","journal-title":"Bull World Health Organ"},{"issue":"5","key":"poi230059r9","doi-asserted-by":"publisher","first-page":"612","DOI":"10.1016\/j.jpeds.2009.06.044","article-title":"Knowledge gaps and research needs for understanding and treating neonatal hypoglycemia: workshop report from Eunice Kennedy Shriver National Institute of Child Health and Human Development.","volume":"155","author":"Hay","year":"2009","journal-title":"J Pediatr"},{"issue":"2","key":"poi230059r10","doi-asserted-by":"publisher","first-page":"385","DOI":"10.1016\/j.pcl.2014.11.004","article-title":"Metabolic screening and postnatal glucose homeostasis in the newborn.","volume":"62","author":"Adamkin","year":"2015","journal-title":"Pediatr Clin North Am"},{"issue":"7","key":"poi230059r11","doi-asserted-by":"publisher","first-page":"513","DOI":"10.1016\/S2352-4642(20)30387-4","article-title":"Strategies to improve neurodevelopmental outcomes in babies at risk of neonatal hypoglycaemia.","volume":"5","author":"Alsweiler","year":"2021","journal-title":"Lancet Child Adolesc Health"},{"issue":"2","key":"poi230059r12","doi-asserted-by":"publisher","first-page":"333","DOI":"10.1016\/j.pcl.2018.12.004","article-title":"Hypoglycemia in the newborn.","volume":"66","author":"Rozance","year":"2019","journal-title":"Pediatr Clin North Am"},{"issue":"4","key":"poi230059r13","first-page":"281","article-title":"[Principles and practice of mass screening for disease].","volume":"65","author":"Wilson","year":"1968","journal-title":"Bol Oficina Sanit Panam"},{"key":"poi230059r14","doi-asserted-by":"publisher","DOI":"10.3389\/fped.2022.1048897","article-title":"Application of the screening test principles to screening for neonatal hypoglycemia.","author":"Alsweiler","year":"2022","journal-title":"Front Pediatr"},{"issue":"12","key":"poi230059r15","doi-asserted-by":"publisher","first-page":"1179","DOI":"10.1016\/j.midw.2014.04.004","article-title":"Do neonatal hypoglycaemia guidelines in Australia and New Zealand facilitate breast feeding?","volume":"30","author":"Sundercombe","year":"2014","journal-title":"Midwifery"},{"issue":"5","key":"poi230059r16","doi-asserted-by":"publisher","first-page":"263","DOI":"10.1016\/j.earlhumdev.2010.05.005","article-title":"Measurement of glucose levels in the newborn.","volume":"86","author":"Beardsall","year":"2010","journal-title":"Early Hum Dev"},{"issue":"10","key":"poi230059r17","doi-asserted-by":"publisher","first-page":"972","DOI":"10.1001\/jamapediatrics.2017.1579","article-title":"Association of neonatal glycemia with neurodevelopmental outcomes at 4.5 years.","volume":"171","author":"McKinlay","year":"2017","journal-title":"JAMA Pediatr"},{"issue":"16","key":"poi230059r18","doi-asserted-by":"publisher","first-page":"1507","DOI":"10.1056\/NEJMoa1504909","article-title":"Neonatal glycemia and neurodevelopmental outcomes at 2 years.","volume":"373","author":"McKinlay","year":"2015","journal-title":"N Engl J Med"},{"issue":"1","key":"poi230059r19","doi-asserted-by":"publisher","first-page":"8132","DOI":"10.1038\/s41598-019-44609-1","article-title":"Factors influencing glycaemic stability after neonatal hypoglycaemia and relationship to neurodevelopmental outcome.","volume":"9","author":"Burakevych","year":"2019","journal-title":"Sci Rep"},{"issue":"18","key":"poi230059r20","doi-asserted-by":"publisher","first-page":"E839","DOI":"10.1503\/cmaj.090449","article-title":"AGREE II: advancing guideline development, reporting and evaluation in health care.","volume":"182","author":"Brouwers","year":"2010","journal-title":"CMAJ"},{"issue":"1","key":"poi230059r21","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1186\/1471-2431-13-59","article-title":"A systematic review and meta-analysis to revise the Fenton growth chart for preterm infants.","volume":"13","author":"Fenton","year":"2013","journal-title":"BMC Pediatr"},{"key":"poi230059r24","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.1003411","article-title":"Evaluation of oral dextrose gel for prevention of neonatal hypoglycemia (hPOD): a multicenter, double-blind randomized controlled trial.","author":"Harding","year":"2021","journal-title":"PLoS Med"},{"issue":"3","key":"poi230059r26","doi-asserted-by":"publisher","first-page":"575","DOI":"10.1542\/peds.2010-3851","article-title":"Postnatal glucose homeostasis in late-preterm and term infants.","volume":"127","author":"Adamkin","year":"2011","journal-title":"Pediatrics"},{"issue":"5","key":"poi230059r27","doi-asserted-by":"publisher","first-page":"353","DOI":"10.1089\/bfm.2021.29178.new","article-title":"ABM Clinical Protocol #1: Guidelines for glucose monitoring and treatment of hypoglycemia in term and late preterm neonates, revised 2021.","volume":"16","author":"Wight","year":"2021","journal-title":"Breastfeed Med"},{"issue":"8","key":"poi230059r31","doi-asserted-by":"publisher","first-page":"536","DOI":"10.1093\/pch\/pxz134","article-title":"The screening and management of newborns at risk for low blood glucose.","volume":"24","author":"Narvey","year":"2019","journal-title":"Paediatr Child Health"},{"issue":"1","key":"poi230059r32","first-page":"1","article-title":"Expert consensus on standard clinical management of neonatal hypoglycemia in China (2021).","volume":"24","author":"Group of Neonatology, Pediatric Society, Chinese Medical Association","year":"2022","journal-title":"Zhongguo Dang Dai Er Ke Za Zhi"},{"issue":"10","key":"poi230059r34","first-page":"31","article-title":"Hypoglycaemia of the breast fed newborn.","volume":"7","author":"National Childbirth Trust","year":"1997","journal-title":"Mod Midwife"},{"issue":"1","key":"poi230059r39","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1111\/apa.v109.1","article-title":"Swedish national guideline for prevention and treatment of neonatal hypoglycaemia in newborn infants with gestational age =35 weeks.","volume":"109","author":"Wackernagel","year":"2020","journal-title":"Acta Paediatr"},{"issue":"18","key":"poi230059r42","doi-asserted-by":"publisher","first-page":"3091","DOI":"10.1080\/14767058.2019.1568985","article-title":"Incidence of hypoglycemia in newborn infants identified as at risk.","volume":"33","author":"Stark","year":"2019","journal-title":"J Matern Fetal Neonatal Med"},{"issue":"1","key":"poi230059r43","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1007\/s004310100847","article-title":"Heterogeneity of persistent hyperinsulinaemic hypoglycaemia. a series of 175 cases.","volume":"161","author":"de Lonlay","year":"2002","journal-title":"Eur J Pediatr"},{"issue":"2","key":"poi230059r44","doi-asserted-by":"publisher","first-page":"583","DOI":"10.15761\/IMM","article-title":"Gestational diabetes in New Zealand ethnic groups.","volume":"3","author":"Jowitt","year":"2016","journal-title":"Integr Mol Med"},{"issue":"2","key":"poi230059r45","doi-asserted-by":"publisher","first-page":"173","DOI":"10.1016\/j.ogc.2007.03.002","article-title":"The increasing prevalence of diabetes in pregnancy.","volume":"34","author":"Hunt","year":"2007","journal-title":"Obstet Gynecol Clin North Am"},{"key":"poi230059r46","doi-asserted-by":"publisher","first-page":"S141","DOI":"10.2337\/dc07-s206","article-title":"Increasing prevalence of gestational diabetes mellitus: a public health perspective.","volume":"30","author":"Ferrara","year":"2007","journal-title":"Diabetes Care"},{"key":"poi230059r47","article-title":"Hypoglycaemia of the newborn: a review.","author":"Williams","year":"1997","journal-title":"Bull World Health Organ"},{"issue":"4","key":"poi230059r48","doi-asserted-by":"publisher","first-page":"913","DOI":"10.1067\/mob.2002.126962","article-title":"Rate and risk factors of hypoglycemia in large-for-gestational-age newborn infants of nondiabetic mothers.","volume":"187","author":"Schaefer-Graf","year":"2002","journal-title":"Am J Obstet Gynecol"},{"issue":"1","key":"poi230059r49","doi-asserted-by":"publisher","first-page":"78","DOI":"10.1136\/adc.2003.039412","article-title":"Neurodevelopmental outcome of hypoglycaemia in healthy, large for gestational age, term newborns.","volume":"90","author":"Brand","year":"2005","journal-title":"Arch Dis Child"},{"key":"poi230059r50","doi-asserted-by":"publisher","first-page":"34","DOI":"10.1016\/j.jpeds.2020.02.079","article-title":"Glucose profiles in healthy term infants in the first 5 days: the Glucose in Well Babies (GLOW) study.","volume":"223","author":"Harris","year":"2020","journal-title":"J Pediatr"},{"issue":"2","key":"poi230059r51","doi-asserted-by":"publisher","first-page":"204","DOI":"10.1097\/MOP.0000000000000592","article-title":"Neonatal hypoglycemia: continuous glucose monitoring.","volume":"30","author":"Shah","year":"2018","journal-title":"Curr Opin Pediatr"},{"issue":"1","key":"poi230059r52","doi-asserted-by":"publisher","first-page":"18","DOI":"10.1186\/s40748-017-0055-z","article-title":"Continuous glucose monitoring in neonates: a review.","volume":"3","author":"McKinlay","year":"2017","journal-title":"Matern Health Neonatol Perinatol"},{"key":"poi230059r53","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD012152.pub3","article-title":"Oral dextrose gel to prevent hypoglycaemia in at-risk neonates.","author":"Hegarty","year":"2021","journal-title":"Cochrane Database Syst Rev"},{"key":"poi230059r54","doi-asserted-by":"publisher","first-page":"80","DOI":"10.1016\/j.jpeds.2020.06.073","article-title":"Cost-utility analysis of prophylactic dextrose gel vs standard care for neonatal hypoglycemia in at-risk infants.","volume":"226","author":"Glasgow","year":"2020","journal-title":"J Pediatr"},{"issue":"12","key":"poi230059r55","doi-asserted-by":"publisher","first-page":"1149","DOI":"10.1001\/jama.2022.2363","article-title":"Prophylactic oral dextrose gel and neurosensory impairment at 2-year follow-up of participants in the hPOD randomized trial.","volume":"327","author":"Edwards","year":"2022","journal-title":"JAMA"},{"issue":"3","key":"poi230059r56","doi-asserted-by":"publisher","first-page":"F229","DOI":"10.1136\/fn.88.3.F229","article-title":"Updated gestational age specific birth weight, crown-heel length, and head circumference of Chinese newborns.","volume":"88","author":"Fok","year":"2003","journal-title":"Arch Dis Child Fetal Neonatal Ed"},{"issue":"6","key":"poi230059r57","doi-asserted-by":"publisher","first-page":"670","DOI":"10.1017\/S000711451800380X","article-title":"Relationship between BMI and adiposity among different ethnic groups in 2-year-old New Zealand children.","volume":"121","author":"Buksh","year":"2019","journal-title":"Br J Nutr"},{"issue":"3","key":"poi230059r58","doi-asserted-by":"publisher","first-page":"567","DOI":"10.1038\/sj.ijo.0803751","article-title":"Application of the 2006 WHO growth standard from birth to 4 years to Pacific Island children.","volume":"32","author":"Rush","year":"2008","journal-title":"Int J Obes (Lond)"},{"key":"poi230059r35","volume-title":"Recommendation for the Treatment of Hypoglycaemia with Dextrose Gel, within the First 48 Hours after Birth in Late Pre-Term and Term Infants","author":"Weston","year":"2015"},{"key":"poi230059r41","volume-title":"Guideline for the Prevention & Management of Hypoglycaemia in High Risk Infants on the Postnatal Ward","author":"Evans","year":"2018"},{"key":"poi230059r22","unstructured":"Fenton? TR, Kim? JH, Stevens? T. Fenton preterm growth chart research bulk calculator. Accessed August 22, 2023. http:\/\/www.ucalgary.ucalgary.ca\/resource\/preterm-growth-chart\/calculators-apps"},{"key":"poi230059r23","unstructured":"New Zealand Ministry of Health. Screening, diagnosis and management of gestational diabetes in New Zealand: a clinical practice guideline. Accessed August 22, 2023. https:\/\/www.health.govt.nz\/publication\/screening-diagnosis-and-management-gestational-diabetes-new-zealand-clinical-practice-guideline"},{"key":"poi230059r25","unstructured":"New Zealand Ministry of Health. Ethnicity data protocols; 2017. Accessed August 22, 2023. https:\/\/www.moh.govt.nz\/notebook\/nbbooks.nsf\/0\/569DDB6A56F7E726CC2581FC00665BEB\/$file\/hiso-10001-2017-ethnicity-data-protocols.pdf"},{"key":"poi230059r28","unstructured":"All India Institute of Medical Sciences. Hypoglycemia in the newborn. Accessed August 29, 2023. https:\/\/www.ontop-in.org\/ontop-pen\/Week-3-4\/Protocol%20hypoglycemia.pdf"},{"key":"poi230059r29","unstructured":"Kalenteryan? H, Mazmanyan? P, Jerjeryan? A, . Care of healthy newborns and management of sick newborns clinical manual. 2016."},{"key":"poi230059r30","unstructured":"British Association of Perinatal Medicine Working Group. Identification and management of neonatal hypoglycaemia in the full term infant. framework for practice. Accessed August 22, 2023. https:\/\/www.bapm.org\/resources\/40-identification-and-management-of-neonatal-hypoglycaemia-in-the-full-term-infant-2017"},{"key":"poi230059r33","unstructured":"Vuiff? ACF, H\u00f8st? B, Zacchariassen? G, ; Danish Paediatric Society. Neonatal hypoglyk\u00e6mi\u2014national guideline. Accessed August 29, 2023. https:\/\/paediatri.dk\/images\/dokumenter\/Retningslinjer_2023\/DPS-vejledning_hypoglyk%C3%A6mi_endelig88.pdf"},{"key":"poi230059r36","unstructured":"Queensland Clinical Guidelines, Queensland Government Department of Health. Queensland clinical guidelines: hypoglycaemia-newborn. Accessed September 5, 2023. https:\/\/www.health.qld.gov.au\/__data\/assets\/pdf_file\/0043\/881899\/g-hypogly.pdf"},{"key":"poi230059r37","unstructured":"Varghese? J, McPhee? A, Morris? S, Stewart? N. Neonatal hypoglycaemia. South Australian perinatal practice guidelines. Accessed August 22, 2023. https:\/\/www.sahealth.sa.gov.au\/wps\/wcm\/connect\/8b64d0004ee49f7584608dd150ce4f37\/Neonatal+Hypoglycaemia_PPG_v5_0.pdf?MOD=AJPERES&CACHEID=ROOTWORKSPACE-8b64d0004ee49f7584608dd150ce4f37-ocQWTNN"},{"key":"poi230059r38","unstructured":"Lorenzo? JRF, Couce Pico? M, Fraga Berm\u00fadez? JM. Hipoglucemia neonatal: protocolos diagn\u00f3stico terape\u00faticos de La AEP: Accessed August 22, 2023. https:\/\/www.aeped.es\/protocolos\/"},{"key":"poi230059r40","unstructured":"Fontijn? J, Neumann? R, Szinnai? G, Schulzke? S. Prevention and treatment of hypoglycaemia in neonates with a gestational age from 35 0\/7 weeks in maternity wards. Accessed August 22, 2023. https:\/\/www.neonet.ch\/download_file\/view\/747\/211"}],"container-title":["JAMA Pediatrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/jamanetwork.com\/journals\/jamapediatrics\/articlepdf\/2810094\/jamapediatrics_obrien_2023_oi_230059_1698695751.32438.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,6]],"date-time":"2023-11-06T11:02:09Z","timestamp":1699268529000},"score":1,"resource":{"primary":{"URL":"https:\/\/jamanetwork.com\/journals\/jamapediatrics\/fullarticle\/2810094"}},"subtitle":["A Systematic Review"],"short-title":[],"issued":{"date-parts":[[2023,11,1]]},"references-count":58,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2023,11,1]]}},"URL":"https:\/\/doi.org\/10.1001\/jamapediatrics.2023.3957","relation":{},"ISSN":["2168-6203"],"issn-type":[{"value":"2168-6203","type":"print"}],"subject":[],"published":{"date-parts":[[2023,11,1]]}}}