{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,5]],"date-time":"2026-11-05T20:43:47Z","timestamp":1793911427252,"version":"4.8.0"},"reference-count":64,"publisher":"American Medical Association (AMA)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JAMA Pediatr"],"published-print":{"date-parts":[[2026,3,1]]},"abstract":"\n Importance<\/jats:title>\n Loneliness and perceived social isolation, with their negative health impacts, are increasing. It is not known whether adolescents with greater levels of family connection experience greater social connection as adults.<\/jats:p>\n <\/jats:sec>\n \n Objective<\/jats:title>\n To determine the association between adolescents\u2019 sense of connection with their families and their overall social connection in adulthood.<\/jats:p>\n <\/jats:sec>\n \n Design, Setting, and Participants<\/jats:title>\n This cohort study of a nationally representative US sample used data from 5 survey waves of The National Longitudinal Study of Adolescent to Adult Health: I (1994-1995), II (1996), III (2001-2002), IV (2008-2009), and V (2016-2018). Wave I involved 20\u202f745 adolescents (grades 7-12), and 7293 participated in all 4 subsequent waves. Data were analyzed from April through November 2025.<\/jats:p>\n <\/jats:sec>\n \n Exposure<\/jats:title>\n Quartiles of adolescent family connection were created using responses to 5 items asked in wave II, and covariates, including indicators of socioeconomic status, were assessed at wave I.<\/jats:p>\n <\/jats:sec>\n \n Main Outcomes and Measures<\/jats:title>\n Adult social connection was assessed at waves IV and V with a score (0-6) created by summing 6 binary measures (no\u2009=\u20090, yes\u2009=\u20091) across 3 dimensions of social connection: structure ([1] participated in weekly activities with relatives\/friends or neighbors, [2] had &amp;gt;2 close friends), function ([3] high perceived social support, [4] never felt isolated), and quality ([5] very close with either parent figure, [6] high relationship satisfaction with partner).<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n The analytic sample contained 7018 of the 7293 respondents to all 5 waves. The mean (SD) ages at waves II, IV, and V were 16.3 (1.8), 28.2 (1.8), and 37.3 (1.9) years, respectively, and 4097 respondents (49.7%) were female. The covariate-adjusted prevalence of high social connection in adulthood (score \u22654) increased across increasing quartiles of family connection in adolescence: 16.1% (95% CI, 13.4%-18.9%) for low, 22.0% (95% CI, 18.9%-25.1%) for medium-low, 28.6% (95% CI, 25.1%-32.1%) for medium-high, and 39.5% (95% CI, 36.2%-42.8%) for high family connection. The prevalence of high social connection in adulthood was 23.4 (95% CI, 19.2-27.6) percentage points greater in those in the highest quartile of adolescent family connection than those in the lowest quartile.<\/jats:p>\n <\/jats:sec>\n \n Conclusions and Relevance<\/jats:title>\n In this cohort study, among US adolescents, those reporting higher family connection had higher levels of social connection as adults up to 2 decades later. 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