{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,3]],"date-time":"2026-11-03T12:19:57Z","timestamp":1793708397050,"version":"4.6.1"},"reference-count":53,"publisher":"American Medical Association (AMA)","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JAMA Psychiatry"],"published-print":{"date-parts":[[2020,6,1]]},"DOI":"10.1001\/jamapsychiatry.2019.4693","type":"journal-article","created":{"date-parts":[[2020,1,29]],"date-time":"2020-01-29T16:31:46Z","timestamp":1580315506000},"page":"563","source":"Crossref","is-referenced-by-count":147,"title":["Outcomes of Online Mindfulness-Based Cognitive Therapy for Patients With Residual Depressive Symptoms"],"prefix":"10.1001","volume":"77","author":[{"given":"Zindel V.","family":"Segal","sequence":"first","affiliation":[{"name":"Graduate Department Psychological Clinical Science, University of Toronto Scarborough, Toronto, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sona","family":"Dimidjian","sequence":"additional","affiliation":[{"name":"University of Colorado Boulder, Boulder"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arne","family":"Beck","sequence":"additional","affiliation":[{"name":"Kaiser Permanente Colorado, Institute for Health Research, Denver"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer M.","family":"Boggs","sequence":"additional","affiliation":[{"name":"Kaiser Permanente Colorado, Institute for Health Research, Denver"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rachel","family":"Vanderkruik","sequence":"additional","affiliation":[{"name":"University of Colorado Boulder, Boulder"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christina A.","family":"Metcalf","sequence":"additional","affiliation":[{"name":"University of Colorado Boulder, Boulder"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Gallop","sequence":"additional","affiliation":[{"name":"Westchester University, Chester County, Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer N.","family":"Felder","sequence":"additional","affiliation":[{"name":"University of California, San Francisco, San Francisco"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph","family":"Levy","sequence":"additional","affiliation":[{"name":"University of Colorado Boulder, Boulder"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"10","reference":[{"issue":"11","key":"yoi190099r1","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pmed.1001547","article-title":"Burden of depressive disorders by country, sex, age, and year: findings from the Global Burden of Disease Study 2010.","volume":"10","author":"Ferrari","year":"2013","journal-title":"PLoS Med"},{"issue":"6","key":"yoi190099r2","doi-asserted-by":"publisher","first-page":"1165","DOI":"10.1017\/S0033291710001911","article-title":"Presence of individual (residual) symptoms during depressive episodes and periods of remission: a 3-year prospective study.","volume":"41","author":"Conradi","year":"2011","journal-title":"Psychol Med"},{"issue":"10","key":"yoi190099r3","doi-asserted-by":"publisher","first-page":"1033","DOI":"10.1001\/jama.2012.271","article-title":"Preventing depression: a global priority.","volume":"307","author":"Cuijpers","year":"2012","journal-title":"JAMA"},{"issue":"3","key":"yoi190099r4","doi-asserted-by":"publisher","first-page":"277","DOI":"10.1016\/j.jad.2012.02.006","article-title":"Depressive episode characteristics and subsequent recurrence risk.","volume":"140","author":"Patten","year":"2012","journal-title":"J Affect Disord"},{"issue":"4","key":"yoi190099r5","doi-asserted-by":"publisher","first-page":"407","DOI":"10.4088\/JCP.12059ah1","article-title":"Residual symptoms in major depressive disorder: prevalence, effects, and management.","volume":"74","author":"Zajecka","year":"2013","journal-title":"J Clin Psychiatry"},{"issue":"2","key":"yoi190099r6","doi-asserted-by":"publisher","first-page":"594","DOI":"10.1016\/j.psychres.2013.06.023","article-title":"Treatment inadequacy in primary and specialized care patients with depressive and\/or anxiety disorders.","volume":"210","author":"Bet","year":"2013","journal-title":"Psychiatry Res"},{"issue":"2","key":"yoi190099r7","doi-asserted-by":"publisher","first-page":"119","DOI":"10.1192\/bjp.bp.116.188078","article-title":"Undertreatment of people with major depressive disorder in 21 countries.","volume":"210","author":"Thornicroft","year":"2017","journal-title":"Br J Psychiatry"},{"issue":"1","key":"yoi190099r8","doi-asserted-by":"publisher","first-page":"41","DOI":"10.1017\/S0033291709006011","article-title":"Residual symptoms after remission of major depressive disorder with citalopram and risk of relapse: a STAR*D report.","volume":"40","author":"Nierenberg","year":"2010","journal-title":"Psychol Med"},{"issue":"4","key":"yoi190099r9","doi-asserted-by":"publisher","first-page":"275","DOI":"10.1176\/appi.ajp.2018.18091075","article-title":"Benefits of sequentially adding cognitive-behavioral therapy or antidepressant medication for adults with nonremitting depression.","volume":"176","author":"Dunlop","year":"2019","journal-title":"Am J Psychiatry"},{"issue":"2","key":"yoi190099r10","doi-asserted-by":"publisher","first-page":"128","DOI":"10.1176\/appi.ajp.2015.15040476","article-title":"The sequential integration of pharmacotherapy and psychotherapy in the treatment of major depressive disorder: a meta-analysis of the sequential model and a critical review of the literature.","volume":"173","author":"Guidi","year":"2016","journal-title":"Am J Psychiatry"},{"issue":"6","key":"yoi190099r11","doi-asserted-by":"publisher","first-page":"966","DOI":"10.1037\/a0013786","article-title":"Mindfulness-based cognitive therapy to prevent relapse in recurrent depression.","volume":"76","author":"Kuyken","year":"2008","journal-title":"J Consult Clin Psychol"},{"issue":"12","key":"yoi190099r12","doi-asserted-by":"publisher","first-page":"1256","DOI":"10.1001\/archgenpsychiatry.2010.168","article-title":"Antidepressant monotherapy vs sequential pharmacotherapy and mindfulness-based cognitive therapy, or placebo, for relapse prophylaxis in recurrent depression.","volume":"67","author":"Segal","year":"2010","journal-title":"Arch Gen Psychiatry"},{"issue":"4","key":"yoi190099r13","doi-asserted-by":"publisher","first-page":"320","DOI":"10.1192\/bjp.bp.111.104851","article-title":"Efficacy of mindfulness-based cognitive therapy in relation to prior history of depression: randomised controlled trial.","volume":"201","author":"Geschwind","year":"2012","journal-title":"Br J Psychiatry"},{"issue":"23","key":"yoi190099r15","doi-asserted-by":"publisher","first-page":"3095","DOI":"10.1001\/jama.289.23.3095","article-title":"The epidemiology of major depressive disorder: results from the National Comorbidity Survey Replication (NCS-R).","volume":"289","author":"Kessler","year":"2003","journal-title":"JAMA"},{"issue":"6","key":"yoi190099r16","doi-asserted-by":"publisher","first-page":"526","DOI":"10.1192\/bjp.184.6.526","article-title":"Utilising survey data to inform public policy: comparison of the cost-effectiveness of treatment of ten mental disorders.","volume":"184","author":"Andrews","year":"2004","journal-title":"Br J Psychiatry"},{"issue":"8","key":"yoi190099r17","doi-asserted-by":"publisher","first-page":"925","DOI":"10.1001\/archpsyc.63.8.925","article-title":"National survey of psychotherapy training in psychiatry, psychology, and social work.","volume":"63","author":"Weissman","year":"2006","journal-title":"Arch Gen Psychiatry"},{"issue":"17","key":"yoi190099r18","doi-asserted-by":"publisher","first-page":"1854","DOI":"10.1001\/jama.2016.4326","article-title":"Effect of a web-based guided self-help intervention for prevention of major depression in adults with subthreshold depression: a randomized clinical trial.","volume":"315","author":"Buntrock","year":"2016","journal-title":"JAMA"},{"issue":"23","key":"yoi190099r19","doi-asserted-by":"publisher","first-page":"2413","DOI":"10.1200\/JCO.2017.76.5669","article-title":"Face-to-face and internet-based mindfulness-based cognitive therapy compared with treatment as usual in reducing psychological distress in patients with cancer: a multicenter randomized controlled trial.","volume":"36","author":"Compen","year":"2018","journal-title":"J Clin Oncol"},{"key":"yoi190099r20","doi-asserted-by":"publisher","first-page":"83","DOI":"10.1016\/j.brat.2014.09.004","article-title":"Web-based mindfulness-based cognitive therapy for reducing residual depressive symptoms: an open trial and quasi-experimental comparison to propensity score matched controls.","volume":"63","author":"Dimidjian","year":"2014","journal-title":"Behav Res Ther"},{"issue":"3","key":"yoi190099r22","doi-asserted-by":"publisher","first-page":"E191","DOI":"10.1503\/cmaj.110829","article-title":"Optimal cut-off score for diagnosing depression with the Patient Health Questionnaire (PHQ-9): a meta-analysis.","volume":"184","author":"Manea","year":"2012","journal-title":"CMAJ"},{"key":"yoi190099r24","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1002\/ace.v2008:120","article-title":"The meaning and role of emotions in adult learning.","volume":"120","author":"Dirkx","year":"2008","journal-title":"New Dir Adult Contin Educ"},{"key":"yoi190099r25","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1002\/(ISSN)1536-0717","article-title":"Adult learners and internet-based distance education.","volume":"78","author":"Eastmond","year":"1998","journal-title":"New Dir Adult Contin Educ"},{"issue":"11","key":"yoi190099r26","doi-asserted-by":"publisher","first-page":"1905","DOI":"10.1176\/ajp.2006.163.11.1905","article-title":"Acute and longer-term outcomes in depressed outpatients requiring one or several treatment steps: a STAR*D report.","volume":"163","author":"Rush","year":"2006","journal-title":"Am J Psychiatry"},{"key":"yoi190099r27","doi-asserted-by":"publisher","first-page":"l1476","DOI":"10.1136\/bmj.l1476","article-title":"Accuracy of Patient Health Questionnaire\u20139 (PHQ-9) for screening to detect major depression: individual participant data meta-analysis.","volume":"365","author":"Levis","year":"2019","journal-title":"BMJ"},{"issue":"10","key":"yoi190099r28","doi-asserted-by":"publisher","first-page":"1092","DOI":"10.1001\/archinte.166.10.1092","article-title":"A brief measure for assessing generalized anxiety disorder: the GAD-7.","volume":"166","author":"Spitzer","year":"2006","journal-title":"Arch Intern Med"},{"issue":"3","key":"yoi190099r29","doi-asserted-by":"publisher","first-page":"220","DOI":"10.1097\/00005650-199603000-00003","article-title":"A 12-Item Short-Form Health Survey: construction of scales and preliminary tests of reliability and validity.","volume":"34","author":"Ware","year":"1996","journal-title":"Med Care"},{"issue":"2","key":"yoi190099r30","doi-asserted-by":"publisher","first-page":"160","DOI":"10.1176\/ps.2010.61.2.160","article-title":"Advantages of using estimated depression-free days for evaluating treatment efficacy.","volume":"61","author":"Vannoy","year":"2010","journal-title":"Psychiatr Serv"},{"issue":"4","key":"yoi190099r32","doi-asserted-by":"publisher","first-page":"933","DOI":"10.2307\/2533433","article-title":"A random-effects ordinal regression model for multilevel analysis.","volume":"50","author":"Hedeker","year":"1994","journal-title":"Biometrics"},{"issue":"20","key":"yoi190099r33","doi-asserted-by":"publisher","first-page":"1462","DOI":"10.1056\/NEJM200005183422001","article-title":"A comparison of nefazodone, the cognitive behavioral-analysis system of psychotherapy, and their combination for the treatment of chronic depression.","volume":"342","author":"Keller","year":"2000","journal-title":"N Engl J Med"},{"issue":"1","key":"yoi190099r35","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1037\/a0014699","article-title":"Effect sizes for growth-modeling analysis for controlled clinical trials in the same metric as for classical analysis.","volume":"14","author":"Feingold","year":"2009","journal-title":"Psychol Methods"},{"issue":"6","key":"yoi190099r36","doi-asserted-by":"publisher","first-page":"1","DOI":"10.18637\/jss.v045.i06","article-title":"Multiple imputation using SAS software.","volume":"45","author":"Yuan","year":"2011","journal-title":"J Stat Softw"},{"issue":"1","key":"yoi190099r37","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1177\/096228029900800102","article-title":"Multiple imputation: a primer.","volume":"8","author":"Schafer","year":"1999","journal-title":"Stat Methods Med Res"},{"issue":"24","key":"yoi190099r40","doi-asserted-by":"publisher","first-page":"2401","DOI":"10.1001\/jama.2019.4990","article-title":"Evolving issues in the treatment of depression.","volume":"321","author":"K\u00f6hler-Forsberg","year":"2019","journal-title":"JAMA"},{"issue":"5","key":"yoi190099r41","doi-asserted-by":"crossref","DOI":"10.2196\/jmir.7725","article-title":"Accelerating digital mental health research from early design and creation to successful implementation and sustainment.","volume":"19","author":"Mohr","year":"2017","journal-title":"J Med Internet Res"},{"issue":"2","key":"yoi190099r42","doi-asserted-by":"publisher","first-page":"275","DOI":"10.1037\/0022-006X.70.2.275","article-title":"Metacognitive awareness and prevention of relapse in depression: empirical evidence.","volume":"70","author":"Teasdale","year":"2002","journal-title":"J Consult Clin Psychol"},{"issue":"7","key":"yoi190099r43","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0070245","article-title":"Cognitive reactivity, implicit associations, and the incidence of depression: a two-year prospective study.","volume":"8","author":"Kruijt","year":"2013","journal-title":"PLoS One"},{"key":"yoi190099r44","doi-asserted-by":"publisher","first-page":"299","DOI":"10.1016\/j.jad.2017.02.029","article-title":"Restoring function in major depressive disorder:  systematic review.","volume":"215","author":"Sheehan","year":"2017","journal-title":"J Affect Disord"},{"key":"yoi190099r45","doi-asserted-by":"publisher","first-page":"115","DOI":"10.1016\/j.jad.2015.04.022","article-title":"The relationship between symptom relief and functional improvement during acute fluoxetine treatment for patients with major depressive disorder.","volume":"182","author":"Lin","year":"2015","journal-title":"J Affect Disord"},{"issue":"2","key":"yoi190099r46","doi-asserted-by":"publisher","first-page":"189","DOI":"10.1037\/ccp0000279","article-title":"Follow-up of monotherapy remitters in the PReDICT study: maintenance treatment outcomes and clinical predictors of recurrence.","volume":"86","author":"Kennedy","year":"2018","journal-title":"J Consult Clin Psychol"},{"issue":"1-3","key":"yoi190099r47","doi-asserted-by":"publisher","first-page":"213","DOI":"10.1016\/j.jad.2012.04.029","article-title":"Cognitive therapy for anxious depression in STAR(*) D: what have we learned?","volume":"142","author":"Farabaugh","year":"2012","journal-title":"J Affect Disord"},{"issue":"23","key":"yoi190099r48","doi-asserted-by":"publisher","first-page":"3135","DOI":"10.1001\/jama.289.23.3135","article-title":"Cost of lost productive work time among US workers with depression.","volume":"289","author":"Stewart","year":"2003","journal-title":"JAMA"},{"issue":"4","key":"yoi190099r49","doi-asserted-by":"publisher","first-page":"305","DOI":"10.1370\/afm.1260","article-title":"Severity of depression and magnitude of productivity loss.","volume":"9","author":"Beck","year":"2011","journal-title":"Ann Fam Med"},{"issue":"4","key":"yoi190099r50","doi-asserted-by":"publisher","first-page":"329","DOI":"10.1016\/j.cpr.2012.02.004","article-title":"Computer-based psychological treatments for depression: a systematic review and meta-analysis.","volume":"32","author":"Richards","year":"2012","journal-title":"Clin Psychol Rev"},{"issue":"1","key":"yoi190099r51","doi-asserted-by":"publisher","first-page":"71","DOI":"10.1016\/j.beth.2017.05.004","article-title":"Effectiveness of web- and mobile-based treatment of subthreshold depression with adherence-focused guidance: a single-blind randomized controlled trial.","volume":"49","author":"Ebert","year":"2018","journal-title":"Behav Ther"},{"issue":"21","key":"yoi190099r52","doi-asserted-by":"publisher","first-page":"2314","DOI":"10.1001\/archinte.166.21.2314","article-title":"Collaborative care for depression: a cumulative meta-analysis and review of longer-term outcomes.","volume":"166","author":"Gilbody","year":"2006","journal-title":"Arch Intern Med"},{"issue":"10","key":"yoi190099r53","doi-asserted-by":"publisher","first-page":"924","DOI":"10.1001\/archpsyc.1996.01830100072009","article-title":"A multifaceted intervention to improve treatment of depression in primary care.","volume":"53","author":"Katon","year":"1996","journal-title":"Arch Gen Psychiatry"},{"key":"yoi190099r14","volume-title":"Integration of mental health\/substance abuse and primary care","author":"Butler","year":"2008"},{"key":"yoi190099r21","volume-title":"SAS\u00ae 9.4 Language Reference: Concepts","author":"SAS Institute Inc","year":"2016","edition":"5th ed"},{"key":"yoi190099r23","volume-title":"Mindfulness-Based Cognitive Therapy for Depression","author":"Segal","year":"2013","edition":"2nd ed"},{"key":"yoi190099r31","volume-title":"Hierarchical Linear Models: Applications and Data Analysis Methods","author":"Raudenbush","year":"2002","edition":"2nd ed"},{"key":"yoi190099r34","volume-title":"Modelling Survival Data in Medical Research","author":"Collett","year":"2014"},{"key":"yoi190099r38","volume-title":"Multiple imputation for Nonresponse in Surveys","author":"Rubin","year":"2004"},{"key":"yoi190099r39","unstructured":"US Bureau of Labor Statistics. Occupational Employment and Wages, May 2018. https:\/\/www.bls.gov\/oes\/current\/oes211091.htm. Updated March 29, 2019. Accessed July 5, 2019."}],"container-title":["JAMA Psychiatry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/jamanetwork.com\/journals\/jamapsychiatry\/articlepdf\/2759418\/jamapsychiatry_segal_2020_oi_190099.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,6,3]],"date-time":"2020-06-03T16:52:32Z","timestamp":1591203152000},"score":1,"resource":{"primary":{"URL":"https:\/\/jamanetwork.com\/journals\/jamapsychiatry\/fullarticle\/2759418"}},"subtitle":["A Randomized Clinical Trial"],"short-title":[],"issued":{"date-parts":[[2020,6,1]]},"references-count":53,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2020,6,1]]}},"URL":"https:\/\/doi.org\/10.1001\/jamapsychiatry.2019.4693","relation":{},"ISSN":["2168-622X"],"issn-type":[{"value":"2168-622X","type":"print"}],"subject":[],"published":{"date-parts":[[2020,6,1]]}}}