{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T22:09:54Z","timestamp":1793398194887,"version":"4.5.0"},"reference-count":99,"publisher":"American Medical Association (AMA)","issue":"7","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JAMA Psychiatry"],"published-print":{"date-parts":[[2020,7,1]]},"DOI":"10.1001\/jamapsychiatry.2019.4779","type":"journal-article","created":{"date-parts":[[2020,3,11]],"date-time":"2020-03-11T15:02:42Z","timestamp":1583938962000},"page":"755","source":"Crossref","is-referenced-by-count":473,"title":["Prevention of Psychosis"],"prefix":"10.1001","volume":"77","author":[{"given":"Paolo","family":"Fusar-Poli","sequence":"first","affiliation":[{"name":"Early Psychosis: Interventions and Clinical-detection (EPIC) Lab, Institute of Psychiatry, Psychology & Neuroscience, Department of Psychosis Studies, King's College London, London, United Kingdom"},{"name":"OASIS Service, South London and Maudsley National Health Service (NHS) Foundation Trust, London, United Kingdom"},{"name":"Department of Brain and Behavioral Sciences, University of Pavia, Pavia, Italy"},{"name":"Maudsley Biomedical Research Centre, National Institute for Health Research, South London and Maudsley NHS Foundation Trust, London, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gonzalo","family":"Salazar de Pablo","sequence":"additional","affiliation":[{"name":"Early Psychosis: Interventions and Clinical-detection (EPIC) Lab, Institute of Psychiatry, Psychology & Neuroscience, Department of Psychosis Studies, King's College London, London, United Kingdom"},{"name":"Institute of Psychiatry and Mental Health, Department of Child and Adolescent Psychiatry, Hospital General Universitario Gregorio Mara\u00f1\u00f3n, Universidad Complutense, Centro de Investigaci\u00f3n Biom\u00e9dica en Red Salud Mental (CIBERSAM), Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christoph U.","family":"Correll","sequence":"additional","affiliation":[{"name":"The Zucker Hillside Hospital, Department of Psychiatry, Northwell Health, Glen Oaks, New York"},{"name":"The Feinstein Institute for Medical Research, Center for Psychiatric Neuroscience, Manhasset, New York"},{"name":"Charit\u00e9 Universit\u00e4tsmedizin Berlin, Department of Child and Adolescent Psychiatry, Berlin, Germany"},{"name":"Department of Psychiatry and Molecular Medicine, Donald and Barbara Zucker School of Medicine at Hofstra\/Northwell, Hempstead, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas","family":"Meyer-Lindenberg","sequence":"additional","affiliation":[{"name":"Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark J.","family":"Millan","sequence":"additional","affiliation":[{"name":"Centre for Therapeutic Innovation in Neuropsychiatry, Institut de Recherche Servier, Croissy sur Seine, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefan","family":"Borgwardt","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, University of Basel, Basel, Switzerland"},{"name":"Department of Psychiatry, Psychosomatics and Psychotherapy, University of L\u00fcbeck, L\u00fcbeck, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvana","family":"Galderisi","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, University of Campania L. Vanvitelli, Naples, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas","family":"Bechdolf","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Psychotherapy and Psychosomatic Medicine with Early Intervention and Recognition Centre, Vivantes Klinikum Am Urban, Charit\u00e9-Universit\u00e4tsmedizin, Berlin, Germany"},{"name":"Vivantes Klinikum im Friedrichshain, Department of Psychiatry, Psychotherapy and Psychosomatic Medicine, Charit\u00e9-Universit\u00e4tsmedizin, Berlin, Germany"},{"name":"Department of Psychiatry and Psychotherapy, University of Cologne, Cologne, Germany"},{"name":"Orygen, The National Centre of Excellence in Youth Mental Health, Melbourne, Victoria, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Pfennig","sequence":"additional","affiliation":[{"name":"Department of Psychiatry and Psychotherapy, Carl Gustav Carus University Hospital, Medical Faculty, Technische Universit\u00e4t Dresden, Dresden, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lars Vedel","family":"Kessing","sequence":"additional","affiliation":[{"name":"Copenhagen Affective Disorder Research Center, Psychiatric Center Copenhagen, Rigshospitalet, Copenhagen, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Therese","family":"van Amelsvoort","sequence":"additional","affiliation":[{"name":"Department of Psychiatry and Neuropsychology, Maastricht University Medical Center School for Mental Health and Neuroscience, Maastricht, the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dorien H.","family":"Nieman","sequence":"additional","affiliation":[{"name":"Amsterdam University Medical Centers, Academic Medical Center, Department of Psychiatry, Amsterdam, the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katharina","family":"Domschke","sequence":"additional","affiliation":[{"name":"Department of Psychiatry and Psychotherapy, Medical Center\u2013University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany"},{"name":"Center for Basics in NeuroModulation (NeuroModul), Medical Faculty, University of Freiburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie-Odile","family":"Krebs","sequence":"additional","affiliation":[{"name":"INSERM, IPNP UMR S1266, Laboratoire de Physiopathologie des Maladies Psychiatriques, Universit\u00e9 Paris Descartes, Universit\u00e9 de Paris, CNRS, GDR3557-Institut de Psychiatrie, Paris, France"},{"name":"Facult\u00e9 de M\u00e9decine Paris Descartes, GHU Paris\u2013Sainte-Anne, Service Hospitalo-Universitaire, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nikolaos","family":"Koutsouleris","sequence":"additional","affiliation":[{"name":"University Hospital, Department of Psychiatry and Psychotherapy, Ludwig Maximilian University of Munich, Munich, Germany"},{"name":"Institute of Psychiatry, Psychology & Neuroscience, Department of Psychosis Studies, King's College London, London, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philip","family":"McGuire","sequence":"additional","affiliation":[{"name":"Maudsley Biomedical Research Centre, National Institute for Health Research, South London and Maudsley NHS Foundation Trust, London, United Kingdom"},{"name":"Institute of Psychiatry, Psychology & Neuroscience, Department of Psychosis Studies, King's College London, London, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kim Q.","family":"Do","sequence":"additional","affiliation":[{"name":"Center for Psychiatric Neuroscience, Lausanne University Hospital, Lausanne-Prilly, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Celso","family":"Arango","sequence":"additional","affiliation":[{"name":"Institute of Psychiatry and Mental Health, Department of Child and Adolescent Psychiatry, Hospital General Universitario Gregorio Mara\u00f1\u00f3n, Universidad Complutense, Centro de Investigaci\u00f3n Biom\u00e9dica en Red Salud Mental (CIBERSAM), Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"10","reference":[{"issue":"6","key":"yrv190007r1","doi-asserted-by":"publisher","first-page":"555","DOI":"10.1001\/jamapsychiatry.2018.0623","article-title":"Comparison of early intervention services vs treatment as usual for early-phase psychosis: a systematic review, meta-analysis, and meta-regression.","volume":"75","author":"Correll","year":"2018","journal-title":"JAMA Psychiatry"},{"issue":"3","key":"yrv190007r2","doi-asserted-by":"publisher","first-page":"251","DOI":"10.1002\/wps.v16.3","article-title":"Improving outcomes of first-episode psychosis: an overview.","volume":"16","author":"Fusar-Poli","year":"2017","journal-title":"World Psychiatry"},{"issue":"11-12","key":"yrv190007r3","doi-asserted-by":"publisher","first-page":"964","DOI":"10.1080\/j.1440-1614.2005.01714.x","article-title":"Mapping the onset of psychosis: the comprehensive assessment of at-risk mental states.","volume":"39","author":"Yung","year":"2005","journal-title":"Aust N Z J Psychiatry"},{"issue":"3","key":"yrv190007r5","doi-asserted-by":"publisher","first-page":"388","DOI":"10.1016\/j.eurpsy.2015.01.013","article-title":"EPA guidance on the early intervention in clinical high risk states of psychoses.","volume":"30","author":"Schmidt","year":"2015","journal-title":"Eur Psychiatry"},{"key":"yrv190007r6","doi-asserted-by":"publisher","first-page":"155","DOI":"10.1146\/annurev-clinpsy-032813-153645","article-title":"Attenuated psychosis syndrome: ready for DSM-5.1?","volume":"10","author":"Fusar-Poli","year":"2014","journal-title":"Annu Rev Clin Psychol"},{"key":"yrv190007r7","article-title":"Clinical validity of DSM-5 attenuated psychosis syndrome: advances in diagnosis, prognosis, and treatment","author":"Salazar de Pablo","journal-title":"JAMA Psychiatry"},{"issue":"1","key":"yrv190007r8","doi-asserted-by":"publisher","first-page":"107","DOI":"10.1001\/jamapsychiatry.2013.269","article-title":"The psychosis high-risk state: a comprehensive state-of-the-art review.","volume":"70","author":"Fusar-Poli","year":"2013","journal-title":"JAMA Psychiatry"},{"issue":"12","key":"yrv190007r9","doi-asserted-by":"publisher","first-page":"1301","DOI":"10.1016\/j.euroneuro.2019.09.006","article-title":"European College of Neuropsychopharmacology Network on the Prevention of Mental Disorders and Mental Health Promotion (ECNP PMD-MHP).","volume":"29","author":"Fusar-Poli","year":"2019","journal-title":"Eur Neuropsychopharmacol"},{"key":"yrv190007r10","doi-asserted-by":"publisher","first-page":"109","DOI":"10.3389\/fpsyt.2019.00109","article-title":"Real world implementation of a transdiagnostic risk calculator for the automatic detection of individuals at risk of psychosis in clinical routine: study protocol.","volume":"10","author":"Fusar-Poli","year":"2019","journal-title":"Front Psychiatry"},{"key":"yrv190007r11","doi-asserted-by":"publisher","first-page":"b2535","DOI":"10.1136\/bmj.b2535","article-title":"Preferred Reporting Items for Systematic Reviews and Meta-Analyses: the PRISMA statement.","volume":"339","author":"Moher","year":"2009","journal-title":"BMJ"},{"issue":"2","key":"yrv190007r12","doi-asserted-by":"publisher","first-page":"128","DOI":"10.7326\/M16-1565","article-title":"A reporting tool for practice guidelines in health care: the RIGHT statement.","volume":"166","author":"Chen","year":"2017","journal-title":"Ann Intern Med"},{"issue":"3","key":"yrv190007r13","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1136\/ebmental-2018-300014","article-title":"Ten simple rules for conducting umbrella reviews.","volume":"21","author":"Fusar-Poli","year":"2018","journal-title":"Evid Based Ment Health"},{"issue":"10","key":"yrv190007r14","doi-asserted-by":"publisher","first-page":"1013","DOI":"10.1016\/j.jclinepi.2008.10.009","article-title":"AMSTAR is a reliable and valid measurement tool to assess the methodological quality of systematic reviews.","volume":"62","author":"Shea","year":"2009","journal-title":"J Clin Epidemiol"},{"issue":"19","key":"yrv190007r16","doi-asserted-by":"publisher","first-page":"2054","DOI":"10.1001\/jama.2015.14905","article-title":"Prostate cancer incidence and PSA testing patterns in relation to USPSTF screening recommendations.","volume":"314","author":"Jemal","year":"2015","journal-title":"JAMA"},{"key":"yrv190007r17","first-page":"S591","article-title":"Interventions and cognitive outcomes in youth at risk of psychosis: a systematic review and meta-analysis.","volume":"42","author":"Addington","year":"2017","journal-title":"Neuropsychopharmacology"},{"issue":"4","key":"yrv190007r18","doi-asserted-by":"publisher","first-page":"394","DOI":"10.1001\/jama.2018.21367","article-title":"Ocular prophylaxis for gonococcal ophthalmia neonatorum: US Preventive Services Task Force reaffirmation recommendation statement.","volume":"321","author":"Curry","year":"2019","journal-title":"JAMA"},{"issue":"20","key":"yrv190007r19","doi-asserted-by":"publisher","first-page":"2122","DOI":"10.1001\/jama.2018.17772","article-title":"Interventions to prevent child maltreatment: US Preventive Services Task Force recommendation statement.","volume":"320","author":"Curry","year":"2018","journal-title":"JAMA"},{"issue":"16","key":"yrv190007r20","doi-asserted-by":"publisher","first-page":"1678","DOI":"10.1001\/jama.2018.14741","article-title":"Screening for intimate partner violence, elder abuse, and abuse of vulnerable adults: US Preventive Services Task Force final recommendation statement.","volume":"320","author":"Curry","year":"2018","journal-title":"JAMA"},{"issue":"11","key":"yrv190007r21","doi-asserted-by":"publisher","first-page":"1163","DOI":"10.1001\/jama.2018.13022","article-title":"Behavioral weight loss interventions to prevent obesity-related morbidity and mortality in adults: US Preventive Services Task Force recommendation statement.","volume":"320","author":"Curry","year":"2018","journal-title":"JAMA"},{"issue":"2","key":"yrv190007r22","doi-asserted-by":"publisher","first-page":"113","DOI":"10.1001\/jamapsychiatry.2015.2324","article-title":"Heterogeneity of psychosis risk within individuals at clinical high risk: a meta-analytical stratification.","volume":"73","author":"Fusar-Poli","year":"2016","journal-title":"JAMA Psychiatry"},{"issue":"2-3","key":"yrv190007r23","doi-asserted-by":"publisher","first-page":"143","DOI":"10.1016\/j.schres.2014.11.026","article-title":"Trauma and recent life events in individuals at ultra high risk for psychosis: review and meta-analysis.","volume":"161","author":"Kraan","year":"2015","journal-title":"Schizophr Res"},{"issue":"4","key":"yrv190007r24","doi-asserted-by":"publisher","first-page":"673","DOI":"10.1017\/S0033291715002329","article-title":"Cannabis use and transition to psychosis in individuals at ultra-high risk: review and meta-analysis.","volume":"46","author":"Kraan","year":"2016","journal-title":"Psychol Med"},{"issue":"1","key":"yrv190007r25","doi-asserted-by":"publisher","first-page":"120","DOI":"10.1093\/schbul\/sbs136","article-title":"Comorbid depressive and anxiety disorders in 509 individuals with an at-risk mental state: impact on psychopathology and transition to psychosis.","volume":"40","author":"Fusar-Poli","year":"2014","journal-title":"Schizophr Bull"},{"issue":"5","key":"yrv190007r26","doi-asserted-by":"publisher","first-page":"911","DOI":"10.1017\/S0033291714002074","article-title":"Are people at risk of psychosis also at risk of suicide and self-harm? a systematic review and meta-analysis.","volume":"45","author":"Taylor","year":"2015","journal-title":"Psychol Med"},{"issue":"3","key":"yrv190007r27","doi-asserted-by":"publisher","first-page":"198","DOI":"10.1192\/bjp.bp.114.157115","article-title":"Disorder, not just state of risk: meta-analysis of functioning and quality of life in people at high risk of psychosis.","volume":"207","author":"Fusar-Poli","year":"2015","journal-title":"Br J Psychiatry"},{"issue":"4","key":"yrv190007r28","doi-asserted-by":"publisher","first-page":"744","DOI":"10.1093\/schbul\/sbt085","article-title":"Meta-analysis of cognitive deficits in ultra-high risk to psychosis and first-episode psychosis: do the cognitive deficits progress over, or after, the onset of psychosis?","volume":"40","author":"Bora","year":"2014","journal-title":"Schizophr Bull"},{"key":"yrv190007r29","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1016\/j.brat.2016.12.004","article-title":"Metacognitive beliefs in the at-risk mental state: a systematic review and meta-analysis.","volume":"90","author":"Cotter","year":"2017","journal-title":"Behav Res Ther"},{"issue":"1-3","key":"yrv190007r30","doi-asserted-by":"publisher","first-page":"28","DOI":"10.1016\/j.schres.2015.02.008","article-title":"Social cognitive functioning in prodromal psychosis: a meta-analysis.","volume":"164","author":"Lee","year":"2015","journal-title":"Schizophr Res"},{"issue":"1-3","key":"yrv190007r31","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1016\/j.schres.2012.12.013","article-title":"Theory of mind impairments in first-episode psychosis, individuals at ultra-high risk for psychosis and in first-degree relatives of schizophrenia: systematic review and meta-analysis.","volume":"144","author":"Bora","year":"2013","journal-title":"Schizophr Res"},{"key":"yrv190007r32","doi-asserted-by":"publisher","first-page":"262","DOI":"10.1016\/j.psyneuen.2015.10.007","article-title":"Salivary cortisol in early psychosis: new findings and meta-analysis.","volume":"63","author":"Chaumette","year":"2016","journal-title":"Psychoneuroendocrinology"},{"key":"yrv190007r33","doi-asserted-by":"crossref","DOI":"10.1016\/j.schres.2019.03.012","article-title":"Meta-analysis of cytokine and C-reactive protein levels in high-risk psychosis.","author":"Park","year":"2019","journal-title":"Schizophr Res"},{"issue":"7","key":"yrv190007r34","doi-asserted-by":"publisher","first-page":"665","DOI":"10.1001\/jamapsychiatry.2016.0442","article-title":"Nature of glutamate alterations in schizophrenia: a meta-analysis of proton magnetic resonance spectroscopy studies.","volume":"73","author":"Merritt","year":"2016","journal-title":"JAMA Psychiatry"},{"key":"yrv190007r35","doi-asserted-by":"publisher","first-page":"122","DOI":"10.1016\/j.jpsychires.2014.08.018","article-title":"Exploring neural dysfunction in \u2018clinical high risk\u2019 for psychosis: a quantitative review of fMRI studies.","volume":"61","author":"Dutt","year":"2015","journal-title":"J Psychiatr Res"},{"key":"yrv190007r36","doi-asserted-by":"publisher","first-page":"16033","DOI":"10.1038\/npjschz.2016.33","article-title":"Alterations in the hippocampus and thalamus in individuals at high risk for psychosis.","volume":"2","author":"Harrisberger","year":"2016","journal-title":"NPJ Schizophr"},{"key":"yrv190007r37","doi-asserted-by":"publisher","first-page":"23","DOI":"10.1016\/j.schres.2018.12.026","article-title":"Pituitary volume in individuals at elevated risk for psychosis: a systematic review and meta-analysis.","volume":"213","author":"Saunders","year":"2019","journal-title":"Schizophr Res"},{"key":"yrv190007r38","doi-asserted-by":"publisher","first-page":"680","DOI":"10.1016\/j.neubiorev.2016.10.007","article-title":"Hippocampal volume in subjects at clinical high-risk for psychosis: a systematic review and meta-analysis.","volume":"71","author":"Walter","year":"2016","journal-title":"Neurosci Biobehav Rev"},{"issue":"12","key":"yrv190007r39","doi-asserted-by":"publisher","first-page":"980","DOI":"10.1016\/j.biopsych.2015.08.025","article-title":"A meta-analysis of mismatch negativity in schizophrenia: from clinical risk to disease specificity and progression.","volume":"79","author":"Erickson","year":"2016","journal-title":"Biol Psychiatry"},{"issue":"4","key":"yrv190007r40","doi-asserted-by":"publisher","first-page":"923","DOI":"10.1093\/schbul\/sbs060","article-title":"At risk for schizophrenic or affective psychoses? a meta-analysis of DSM\/ICD diagnostic outcomes in individuals at high clinical risk.","volume":"39","author":"Fusar-Poli","year":"2013","journal-title":"Schizophr Bull"},{"issue":"3","key":"yrv190007r41","doi-asserted-by":"publisher","first-page":"732","DOI":"10.1093\/schbul\/sbv162","article-title":"The dark side of the moon: meta-analytical impact of recruitment strategies on risk enrichment in the clinical high risk state for psychosis.","volume":"42","author":"Fusar-Poli","year":"2016","journal-title":"Schizophr Bull"},{"issue":"3","key":"yrv190007r42","doi-asserted-by":"publisher","first-page":"322","DOI":"10.1002\/wps.20250","article-title":"At risk or not at risk? a meta-analysis of the prognostic accuracy of psychometric interviews for psychosis prediction.","volume":"14","author":"Fusar-Poli","year":"2015","journal-title":"World Psychiatry"},{"key":"yrv190007r43","doi-asserted-by":"publisher","first-page":"62","DOI":"10.1016\/j.eurpsy.2017.10.001","article-title":"Meta-analytical prognostic accuracy of the Comprehensive Assessment of At Risk Mental States (CAARMS): the need for refined prediction.","volume":"49","author":"Oliver","year":"2018","journal-title":"Eur Psychiatry"},{"issue":"2","key":"yrv190007r44","first-page":"375","article-title":"Improving prognostic accuracy in subjects at clinical high risk for psychosis: systematic review of predictive models and meta-analytical sequential testing simulation.","volume":"43","author":"Schmidt","year":"2017","journal-title":"Schizophr Bull"},{"issue":"3","key":"yrv190007r45","doi-asserted-by":"publisher","first-page":"266","DOI":"10.1016\/j.psychres.2013.03.004","article-title":"Moving beyond transition outcomes: meta-analysis of remission rates in individuals at high clinical risk for psychosis.","volume":"209","author":"Simon","year":"2013","journal-title":"Psychiatry Res"},{"key":"yrv190007r46","doi-asserted-by":"publisher","first-page":"187","DOI":"10.3389\/fpsyt.2018.00187","article-title":"Efficacy and acceptability of interventions for attenuated positive psychotic symptoms in individuals at clinical high risk of psychosis: a network meta-analysis.","volume":"9","author":"Davies","year":"2018","journal-title":"Front Psychiatry"},{"issue":"2","key":"yrv190007r47","doi-asserted-by":"publisher","first-page":"196","DOI":"10.1002\/wps.v17.2","article-title":"Lack of evidence to favor specific preventive interventions in psychosis: a network meta-analysis.","volume":"17","author":"Davies","year":"2018","journal-title":"World Psychiatry"},{"issue":"1","key":"yrv190007r48","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1111\/eip.2019.13.issue-1","article-title":"Attenuated psychotic symptom interventions in youth at risk of psychosis: a systematic review and meta-analysis.","volume":"13","author":"Devoe","year":"2019","journal-title":"Early Interv Psychiatry"},{"issue":"4","key":"yrv190007r49","doi-asserted-by":"publisher","first-page":"807","DOI":"10.1093\/schbul\/sbx139","article-title":"Negative symptom interventions in youth at risk of psychosis: a systematic review and network meta-analysis.","volume":"44","author":"Devoe","year":"2018","journal-title":"Schizophr Bull"},{"issue":"2","key":"yrv190007r50","doi-asserted-by":"publisher","first-page":"169","DOI":"10.1111\/eip.2019.13.issue-2","article-title":"Interventions and social functioning in youth at risk of psychosis: a systematic review and meta-analysis.","volume":"13","author":"Devoe","year":"2019","journal-title":"Early Interv Psychiatry"},{"issue":"3","key":"yrv190007r51","doi-asserted-by":"publisher","first-page":"449","DOI":"10.1017\/S0033291713000354","article-title":"Cognitive behavioural therapy for psychosis prevention: a systematic review and meta-analysis.","volume":"44","author":"Hutton","year":"2014","journal-title":"Psychol Med"},{"key":"yrv190007r52","doi-asserted-by":"publisher","first-page":"f185","DOI":"10.1136\/bmj.f185","article-title":"Early interventions to prevent psychosis: systematic review and meta-analysis.","volume":"346","author":"Stafford","year":"2013","journal-title":"BMJ"},{"issue":"1","key":"yrv190007r53","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1111\/acps.2017.136.issue-1","article-title":"Cannabis use and symptom severity in individuals at ultra high risk for psychosis: a meta-analysis.","volume":"136","author":"Carney","year":"2017","journal-title":"Acta Psychiatr Scand"},{"issue":"1","key":"yrv190007r54","doi-asserted-by":"publisher","first-page":"e28","DOI":"10.4088\/JCP.15r10197","article-title":"Neuropsychological test performance to enhance identification of subjects at clinical high risk for psychosis and to be most promising for predictive algorithms for conversion to psychosis: a meta-analysis.","volume":"78","author":"Hauser","year":"2017","journal-title":"J Clin Psychiatry"},{"key":"yrv190007r55","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1016\/j.eurpsy.2016.09.003","article-title":"Deconstructing vulnerability for psychosis: meta-analysis of environmental risk factors for psychosis in subjects at ultra high-risk.","volume":"40","author":"Fusar-Poli","year":"2017","journal-title":"Eur Psychiatry"},{"issue":"7","key":"yrv190007r56","doi-asserted-by":"publisher","first-page":"1089","DOI":"10.1017\/S003329171800394X","article-title":"Childhood adversities in people at ultra-high risk (UHR) for psychosis: a systematic review and meta-analysis.","volume":"49","author":"Peh","year":"2019","journal-title":"Psychol Med"},{"issue":"1","key":"yrv190007r57","doi-asserted-by":"publisher","first-page":"50","DOI":"10.1093\/schbul\/sbt049","article-title":"Meta-analysis of olfactory function in schizophrenia, first-degree family members, and youths at-risk for psychosis.","volume":"40","author":"Moberg","year":"2014","journal-title":"Schizophr Bull"},{"issue":"2-3","key":"yrv190007r58","doi-asserted-by":"publisher","first-page":"290","DOI":"10.1016\/j.schres.2016.01.010","article-title":"Cardiometabolic risk factors in young people at ultra-high risk for psychosis: a systematic review and meta-analysis.","volume":"170","author":"Carney","year":"2016","journal-title":"Schizophr Res"},{"issue":"11","key":"yrv190007r59","doi-asserted-by":"publisher","first-page":"951","DOI":"10.1016\/j.biopsych.2014.09.025","article-title":"Forecasting psychosis by event-related potentials-systematic review and specific meta-analysis.","volume":"77","author":"Bodatsch","year":"2015","journal-title":"Biol Psychiatry"},{"issue":"7","key":"yrv190007r60","doi-asserted-by":"publisher","first-page":"1300","DOI":"10.1038\/s41386-018-0311-6","article-title":"Oxytocin modulates hippocampal perfusion in people at clinical high risk for psychosis.","volume":"44","author":"Davies","year":"2019","journal-title":"Neuropsychopharmacology"},{"issue":"6","key":"yrv190007r61","doi-asserted-by":"publisher","first-page":"622","DOI":"10.1001\/jamapsychiatry.2015.0094","article-title":"Speed of psychosis progression in people at ultra-high clinical risk: a complementary meta-analysis.","volume":"72","author":"Kempton","year":"2015","journal-title":"JAMA Psychiatry"},{"issue":"3","key":"yrv190007r62","doi-asserted-by":"publisher","first-page":"211","DOI":"10.1001\/jamapsychiatry.2015.2313","article-title":"Prognosis of brief psychotic episodes: a meta-analysis.","volume":"73","author":"Fusar-Poli","year":"2016","journal-title":"JAMA Psychiatry"},{"key":"yrv190007r63","article-title":"What causes the onset of psychosis in individuals at clinical high risk? a meta-analysis of risk and protective factors.","author":"Oliver","year":"2019","journal-title":"Schizophr Bull"},{"issue":"5","key":"yrv190007r64","doi-asserted-by":"publisher","first-page":"493","DOI":"10.1001\/jamapsychiatry.2017.0284","article-title":"Development and validation of a clinically based risk calculator for the transdiagnostic prediction of psychosis.","volume":"74","author":"Fusar-Poli","year":"2017","journal-title":"JAMA Psychiatry"},{"issue":"2","key":"yrv190007r65","doi-asserted-by":"publisher","first-page":"133","DOI":"10.1002\/wps.v17.2","article-title":"Beyond the \u201cat risk mental state\u201d concept: transitioning to transdiagnostic psychiatry.","volume":"17","author":"McGorry","year":"2018","journal-title":"World Psychiatry"},{"issue":"1","key":"yrv190007r66","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1001\/jamapsychiatry.2018.2552","article-title":"Association of pre-onset subthreshold psychotic symptoms with longitudinal outcomes during treatment of a first episode of psychosis.","volume":"76","author":"Rosengard","year":"2019","journal-title":"JAMA Psychiatry"},{"issue":"2","key":"yrv190007r67","doi-asserted-by":"publisher","first-page":"276","DOI":"10.1093\/schbul\/sbx173","article-title":"Can we predict psychosis outside the clinical high-risk state? A systematic review of non-psychotic risk syndromes for mental disorders.","volume":"44","author":"Lee","year":"2018","journal-title":"Schizophr Bull"},{"issue":"3","key":"yrv190007r68","doi-asserted-by":"publisher","first-page":"562","DOI":"10.1093\/schbul\/sby070","article-title":"Transdiagnostic risk calculator for the automatic detection of individuals at risk and the prediction of psychosis: second replication in an independent National Health Service Trust.","volume":"45","author":"Fusar-Poli","year":"2019","journal-title":"Schizophr Bull"},{"issue":"3","key":"yrv190007r69","doi-asserted-by":"publisher","first-page":"600","DOI":"10.1093\/schbul\/sby069","article-title":"Using online screening in the general population to detect participants at clinical high-risk for psychosis.","volume":"45","author":"McDonald","year":"2019","journal-title":"Schizophr Bull"},{"issue":"2","key":"yrv190007r70","doi-asserted-by":"publisher","first-page":"192","DOI":"10.1002\/wps.v18.2","article-title":"Transdiagnostic psychiatry: a systematic review.","volume":"18","author":"Fusar-Poli","year":"2019","journal-title":"World Psychiatry"},{"key":"yrv190007r71","doi-asserted-by":"publisher","first-page":"774","DOI":"10.3389\/fpsyt.2019.00774","article-title":"Improving the detection of individuals at clinical risk for psychosis in the community, primary and secondary care: an integrated evidence-based approach.","volume":"10","author":"Fusar-Poli","year":"2019","journal-title":"Front Psychiatry"},{"issue":"1","key":"yrv190007r72","doi-asserted-by":"publisher","first-page":"159","DOI":"10.1111\/eip.2019.13.issue-1","article-title":"Australia\u2019s innovation in youth mental health care: the headspace centre model.","volume":"13","author":"Rickwood","year":"2019","journal-title":"Early Interv Psychiatry"},{"issue":"1","key":"yrv190007r73","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1002\/wps.v17.1","article-title":"What causes psychosis? an umbrella review of risk and protective factors.","volume":"17","author":"Radua","year":"2018","journal-title":"World Psychiatry"},{"key":"yrv190007r74","doi-asserted-by":"publisher","first-page":"174","DOI":"10.3389\/fpsyt.2019.00174","article-title":"Psychosis Polyrisk Score (PPS) for the detection of individuals at risk and the prediction of their outcomes.","volume":"10","author":"Oliver","year":"2019","journal-title":"Front Psychiatry"},{"issue":"12","key":"yrv190007r75","doi-asserted-by":"publisher","first-page":"1289","DOI":"10.1001\/jamapsychiatry.2018.2530","article-title":"The science of prognosis in psychiatry: a review.","volume":"75","author":"Fusar-Poli","year":"2018","journal-title":"JAMA Psychiatry"},{"issue":"5","key":"yrv190007r76","doi-asserted-by":"publisher","first-page":"505","DOI":"10.1111\/bdi.2014.16.issue-5","article-title":"The Bipolar Prodrome Symptom Interview and Scale-Prospective (BPSS-P): description and validation in a psychiatric sample and healthy controls.","volume":"16","author":"Correll","year":"2014","journal-title":"Bipolar Disord"},{"key":"yrv190007r77","doi-asserted-by":"publisher","first-page":"302","DOI":"10.1016\/j.psychres.2018.03.074","article-title":"Semistructured Interview for Bipolar At Risk States (SIBARS).","volume":"264","author":"Fusar-Poli","year":"2018","journal-title":"Psychiatry Res"},{"issue":"1","key":"yrv190007r78","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1136\/eb-2015-102295","article-title":"Predicting the onset of psychosis in patients at clinical high risk: practical guide to probabilistic prognostic reasoning.","volume":"19","author":"Fusar-Poli","year":"2016","journal-title":"Evid Based Ment Health"},{"issue":"12","key":"yrv190007r79","doi-asserted-by":"publisher","first-page":"1260","DOI":"10.1001\/jamapsychiatry.2016.2707","article-title":"Deconstructing pretest risk enrichment to optimize prediction of psychosis in individuals at clinical high risk.","volume":"73","author":"Fusar-Poli","year":"2016","journal-title":"JAMA Psychiatry"},{"issue":"3","key":"yrv190007r80","doi-asserted-by":"publisher","first-page":"220","DOI":"10.1001\/archgenpsychiatry.2011.1472","article-title":"Predicting psychosis: meta-analysis of transition outcomes in individuals at high clinical risk.","volume":"69","author":"Fusar-Poli","year":"2012","journal-title":"Arch Gen Psychiatry"},{"key":"yrv190007r81","doi-asserted-by":"publisher","first-page":"385","DOI":"10.1016\/j.schres.2017.06.015","article-title":"Why transition risk to psychosis is not declining at the OASIS ultra high risk service: the hidden role of stable pretest risk enrichment.","volume":"192","author":"Fusar-Poli","year":"2018","journal-title":"Schizophr Res"},{"issue":"1","key":"yrv190007r82","doi-asserted-by":"publisher","first-page":"48","DOI":"10.1093\/schbul\/sbw151","article-title":"Diagnostic and prognostic significance of Brief Limited Intermittent Psychotic Symptoms (BLIPS) in individuals at ultra high risk.","volume":"43","author":"Fusar-Poli","year":"2017","journal-title":"Schizophr Bull"},{"issue":"1","key":"yrv190007r83","doi-asserted-by":"publisher","first-page":"44","DOI":"10.1093\/schbul\/sbw158","article-title":"The Clinical High-Risk state for psychosis (CHR-P), version II.","volume":"43","author":"Fusar-Poli","year":"2017","journal-title":"Schizophr Bull"},{"issue":"1","key":"yrv190007r84","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1111\/acps.2014.130.issue-1","article-title":"Cognitive deficits in youth with familial and clinical high risk to psychosis: a systematic review and meta-analysis.","volume":"130","author":"Bora","year":"2014","journal-title":"Acta Psychiatr Scand"},{"issue":"10","key":"yrv190007r85","doi-asserted-by":"publisher","first-page":"980","DOI":"10.1176\/appi.ajp.2016.15070890","article-title":"An individualized risk calculator for research in prodromal psychosis.","volume":"173","author":"Cannon","year":"2016","journal-title":"Am J Psychiatry"},{"issue":"11","key":"yrv190007r86","doi-asserted-by":"publisher","first-page":"1156","DOI":"10.1001\/jamapsychiatry.2018.2165","article-title":"Prediction models of functional outcomes for individuals in the clinical high-risk state for psychosis or with recent-onset depression: a multimodal, multisite machine learning analysis.","volume":"75","author":"Koutsouleris","year":"2018","journal-title":"JAMA Psychiatry"},{"key":"yrv190007r87","article-title":"Development and validation of a dynamic risk prediction model to forecast psychosis onset in patients at clinical high risk [published online July 29, 2019].","author":"Studerus","journal-title":"Schizophr Bull"},{"issue":"5","key":"yrv190007r88","doi-asserted-by":"publisher","first-page":"528","DOI":"10.1001\/jamapsychiatry.2017.0001","article-title":"Moving from static to dynamic models of the onset of mental disorder: a review.","volume":"74","author":"Nelson","year":"2017","journal-title":"JAMA Psychiatry"},{"key":"yrv190007r89","doi-asserted-by":"publisher","first-page":"209","DOI":"10.1016\/j.schres.2019.02.019","article-title":"Towards a framework for good outcome in people at clinical high risk for psychosis: a Delphi consensus study.","volume":"208","author":"Petros","year":"2019","journal-title":"Schizophr Res"},{"issue":"1-3","key":"yrv190007r90","doi-asserted-by":"publisher","first-page":"56","DOI":"10.1016\/j.schres.2013.07.004","article-title":"Preventing a first episode of psychosis: meta-analysis of randomized controlled prevention trials of 12 month and longer-term follow-ups.","volume":"149","author":"van der Gaag","year":"2013","journal-title":"Schizophr Res"},{"issue":"11","key":"yrv190007r91","article-title":"Interventions for prodromal stage of psychosis.","volume":"2019","author":"Bosnjak Kuharic","year":"2019","journal-title":"Cochrane Database Syst Rev"},{"issue":"6","key":"yrv190007r92","doi-asserted-by":"publisher","first-page":"651","DOI":"10.1001\/jamapsychiatry.2017.0185","article-title":"Negative psychosis prevention trials.","volume":"74","author":"Fusar-Poli","year":"2017","journal-title":"JAMA Psychiatry"},{"issue":"7","key":"yrv190007r93","doi-asserted-by":"publisher","first-page":"485","DOI":"10.1038\/nrd.2016.28","article-title":"Altering the course of schizophrenia: progress and perspectives.","volume":"15","author":"Millan","year":"2016","journal-title":"Nat Rev Drug Discov"},{"issue":"7","key":"yrv190007r94","doi-asserted-by":"publisher","first-page":"591","DOI":"10.1016\/S2215-0366(18)30057-9","article-title":"Preventive strategies for mental health.","volume":"5","author":"Arango","year":"2018","journal-title":"Lancet Psychiatry"},{"key":"yrv190007r95","doi-asserted-by":"publisher","first-page":"16003","DOI":"10.1038\/npjschz.2016.3","article-title":"Early interventions in risk groups for schizophrenia: what are we waiting for?","volume":"2","author":"Sommer","year":"2016","journal-title":"NPJ Schizophr"},{"issue":"3","key":"yrv190007r96","doi-asserted-by":"publisher","first-page":"1201","DOI":"10.1159\/000491986","article-title":"Impact on the onset of psychosis of a polygenic schizophrenia-related risk score and changes in white matter volume.","volume":"48","author":"Harrisberger","year":"2018","journal-title":"Cell Physiol Biochem"},{"issue":"3","key":"yrv190007r97","doi-asserted-by":"publisher","first-page":"485","DOI":"10.1111\/milq.2016.94.issue-3","article-title":"The mass production of redundant, misleading, and conflicted systematic reviews and meta-analyses.","volume":"94","author":"Ioannidis","year":"2016","journal-title":"Milbank Q"},{"key":"yrv190007r98","doi-asserted-by":"publisher","first-page":"f4501","DOI":"10.1136\/bmj.f4501","article-title":"Overlapping meta-analyses on the same topic: survey of published studies.","volume":"347","author":"Siontis","year":"2013","journal-title":"BMJ"},{"issue":"6","key":"yrv190007r99","doi-asserted-by":"publisher","first-page":"1999","DOI":"10.1093\/ije\/dyx138","article-title":"Overlapping network meta-analyses on the same topic: survey of published studies.","volume":"46","author":"Naudet","year":"2017","journal-title":"Int J Epidemiol"},{"key":"yrv190007r4","unstructured":"National Institute for Health and Care Excellence. Psychosis and schizophrenia in adults: prevention and management. https:\/\/www.nice.org.uk\/guidance\/cg178\/chapter\/1-Recommendations#preventing-psychosis-2. Updated March 2014. Accessed April 8, 2016."},{"key":"yrv190007r15","unstructured":"U.S. Preventive Services Task Force. Grade definitions. https:\/\/www.uspreventiveservicestaskforce.org\/Page\/Name\/grade-definitions. Updated June 2018. Accessed March 20, 2019."}],"container-title":["JAMA Psychiatry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/jamanetwork.com\/journals\/jamapsychiatry\/articlepdf\/2762529\/jamapsychiatry_fusarpoli_2020_rv_190007.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,7,1]],"date-time":"2020-07-01T15:03:24Z","timestamp":1593615804000},"score":1,"resource":{"primary":{"URL":"https:\/\/jamanetwork.com\/journals\/jamapsychiatry\/fullarticle\/2762529"}},"subtitle":["Advances in Detection, Prognosis, and Intervention"],"short-title":[],"issued":{"date-parts":[[2020,7,1]]},"references-count":99,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2020,7,1]]}},"URL":"https:\/\/doi.org\/10.1001\/jamapsychiatry.2019.4779","relation":{},"ISSN":["2168-622X"],"issn-type":[{"value":"2168-622X","type":"print"}],"subject":[],"published":{"date-parts":[[2020,7,1]]}}}