{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T15:12:47Z","timestamp":1792509167822,"version":"4.5.0"},"reference-count":40,"publisher":"American Medical Association (AMA)","issue":"11","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JAMA Psychiatry"],"published-print":{"date-parts":[[2023,11,1]]},"abstract":"<jats:sec id=\"ab-yoi230064-4\"><jats:title>Importance<\/jats:title><jats:p>Alcohol misuse in adolescence is a leading cause of disability and mortality in youth and is associated with higher risk for alcohol use disorder. Brain mechanisms underlying risk of alcohol misuse may inform prevention and intervention efforts.<\/jats:p><\/jats:sec><jats:sec id=\"ab-yoi230064-5\"><jats:title>Objective<\/jats:title><jats:p>To identify neuromarkers of alcohol misuse using a data-driven approach, with specific consideration of neurodevelopmental sex differences.<\/jats:p><\/jats:sec><jats:sec id=\"ab-yoi230064-6\"><jats:title>Design, Setting, and Participants<\/jats:title><jats:p>Longitudinal multisite functional magnetic resonance imaging (fMRI) data collected at ages 14 and 19 years were used to assess whole-brain patterns of functional organization associated with current and future alcohol use risk as measured by the Alcohol Use Disorder Identification Test (AUDIT). Primary data were collected by the IMAGEN consortium, a European multisite study of adolescent neurodevelopment. Model generalizability was further tested using data acquired in a single-site study of college alcohol consumption conducted in the US. The primary sample was a developmental cohort of 1359 adolescents with neuroimaging, phenotyping, and alcohol use data. Model generalizability was further assessed in a separate cohort of 114 individuals.<\/jats:p><\/jats:sec><jats:sec id=\"ab-yoi230064-7\"><jats:title>Main Outcomes and Measures<\/jats:title><jats:p>Brain-behavior model accuracy, as defined by the correspondence between model-predicted and actual AUDIT scores in held-out testing data, Bonferroni corrected across the number of models run at each time point, 2-tailed \u03b1\u2009&amp;amp;lt;\u2009.008, as determined via permutation testing.<\/jats:p><\/jats:sec><jats:sec id=\"ab-yoi230064-8\"><jats:title>Results<\/jats:title><jats:p>Among 1359 individuals in the study, the mean (SD) age was 14.42 (0.40) years, and 729 individuals (54%) were female. The data-driven, whole-brain connectivity approach identified networks associated with vulnerability for future and current AUDIT-defined alcohol use risk (primary outcome, as specified above, future: \u03c1, 0.22; <jats:italic>P<\/jats:italic>\u2009&amp;amp;lt;\u2009.001 and present: \u03c1, 0.27; <jats:italic>P<\/jats:italic>\u2009&amp;amp;lt;\u2009.001). Results further indicated sex divergence in the accuracies of brain-behavior models, such that female-only models consistently outperformed male-only models. Specifically, female-only models identified networks conferring vulnerability for future and current severity using data acquired during both reward and inhibitory fMRI tasks. In contrast, male-only models were successful in accurately identifying networks using data acquired during the inhibitory control\u2014but not reward\u2014task, indicating domain specificity of alcohol use risk networks in male adolescents only.<\/jats:p><\/jats:sec><jats:sec id=\"ab-yoi230064-9\"><jats:title>Conclusions and Relevance<\/jats:title><jats:p>These data suggest that interventions focusing on inhibitory control processes may be effective in combating alcohol use risk in male adolescents but that both inhibitory and reward-related processes are likely of relevance to alcohol use behaviors in female adolescents. They further identify novel networks of alcohol use risk in youth, which may be used to identify adolescents who are at risk and inform intervention efforts.<\/jats:p><\/jats:sec>","DOI":"10.1001\/jamapsychiatry.2023.2949","type":"journal-article","created":{"date-parts":[[2023,8,30]],"date-time":"2023-08-30T11:36:30Z","timestamp":1693395390000},"page":"1131","source":"Crossref","is-referenced-by-count":34,"title":["Brain Networks and Adolescent Alcohol Use"],"prefix":"10.1001","volume":"80","author":[{"given":"Sarah W.","family":"Yip","sequence":"first","affiliation":[{"name":"Department of Psychiatry, Yale School of Medicine, Yale University, New Haven, Connecticut"},{"name":"Child Study Center, Yale School of Medicine, New Haven, Connecticut"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah D.","family":"Lichenstein","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Yale School of Medicine, Yale University, New Haven, Connecticut"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qinghao","family":"Liang","sequence":"additional","affiliation":[{"name":"Department of Biomedical Engineering, Yale School of Medicine, New Haven, Connecticut"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bader","family":"Chaarani","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, University of Vermont, Burlington"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alecia","family":"Dager","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Yale School of Medicine, Yale University, New Haven, Connecticut"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Godfrey","family":"Pearlson","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Yale School of Medicine, Yale University, New Haven, Connecticut"},{"name":"Department of Neuroscience, Yale School of Medicine, New Haven, Connecticut"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tobias","family":"Banaschewski","sequence":"additional","affiliation":[{"name":"Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arun L. W.","family":"Bokde","sequence":"additional","affiliation":[{"name":"Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, King\u2019s College London, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sylvane","family":"Desrivi\u00e8res","sequence":"additional","affiliation":[{"name":"Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, King\u2019s College London, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Herta","family":"Flor","sequence":"additional","affiliation":[{"name":"Institute of Cognitive and Clinical Neuroscience, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany"},{"name":"Department of Psychology, School of Social Sciences, University of Mannheim, Mannheim, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antoine","family":"Grigis","sequence":"additional","affiliation":[{"name":"Department of Psychology, School of Social Sciences, University of Mannheim, Mannheim, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Penny","family":"Gowland","sequence":"additional","affiliation":[{"name":"Sir Peter Mansfield Imaging Centre School of Physics and Astronomy, University of Nottingham, University Park, Nottingham, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas","family":"Heinz","sequence":"additional","affiliation":[{"name":"Department of Psychiatry and Psychotherapy Campus Charit\u00e9 Mitte, Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin, Freie Universit\u00e4t Berlin, Humboldt-Universit\u00e4t zu Berlin, and Berlin Institute of Health, Berlin, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R\u00fcdiger","family":"Br\u00fchl","sequence":"additional","affiliation":[{"name":"Physikalisch-Technische Bundesanstalt, Braunschweig and Berlin, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Luc","family":"Martinot","sequence":"additional","affiliation":[{"name":"Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale, INSERM U 1299 Trajectoires d\u00e9veloppementales & psychiatrie, University Paris-Saclay, University Paris Cit\u00e9, CNRS, Ecole Normale Sup\u00e9rieure Paris-Saclay, Centre Borelli, Gif-sur-Yvette, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie-Laure Paill\u00e8re","family":"Martinot","sequence":"additional","affiliation":[{"name":"Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale, INSERM U 1299 Trajectoires d\u00e9veloppementales & psychiatrie, University Paris-Saclay, CNRS, Ecole Normale Sup\u00e9rieure Paris-Saclay, Centre Borelli, Gif-sur-Yvette, and AP-HP, Sorbonne University, Department of Child and Adolescent Psychiatry, Piti\u00e9-Salp\u00eatri\u00e8re Hospital, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric","family":"Artiges","sequence":"additional","affiliation":[{"name":"Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale, INSERM U 1299 Trajectoires d\u00e9veloppementales & psychiatrie, University Paris-Saclay, CNRS, Ecole Normale Sup\u00e9rieure Paris-Saclay, Centre Borelli, Gif-sur-Yvette, and Psychiatry Department, EPS Barth\u00e9l\u00e9my Durand, Etampes, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frauke","family":"Nees","sequence":"additional","affiliation":[{"name":"Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany"},{"name":"Institute of Cognitive and Clinical Neuroscience, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany"},{"name":"Institute of Medical Psychology and Medical Sociology, University Medical Center Schleswig-Holstein, Kiel University, Kiel, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dimitri Papadopoulos","family":"Orfanos","sequence":"additional","affiliation":[{"name":"NeuroSpin, Alternative Energies and Atomic Energy Commission, Universit\u00e9 Paris-Saclay, Gif-sur-Yvette, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tom\u00e1\u0161","family":"Paus","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Faculty of Medicine and Centre Hospitalier Universitaire Sainte-Justine, University of Montreal, Montreal, Quebec, Canada"},{"name":"Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada"},{"name":"Department of Psychology, University of Toronto, Toronto, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luise","family":"Poustka","sequence":"additional","affiliation":[{"name":"Department of Child and Adolescent Psychiatry and Psychotherapy, University Medical Centre G\u00f6ttingen, G\u00f6ttingen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah","family":"Hohmann","sequence":"additional","affiliation":[{"name":"Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sabina","family":"Millenet","sequence":"additional","affiliation":[{"name":"Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juliane H.","family":"Fr\u00f6hner","sequence":"additional","affiliation":[{"name":"Department of Psychiatry and Neuroimaging Center, Technische Universit\u00e4t Dresden, Dresden, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael N.","family":"Smolka","sequence":"additional","affiliation":[{"name":"Department of Psychiatry and Neuroimaging Center, Technische Universit\u00e4t Dresden, Dresden, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nilakshi","family":"Vaidya","sequence":"additional","affiliation":[{"name":"Centre for Population Neuroscience and Stratified Medicine, Department of Psychiatry and Psychotherapy, Charit\u00e9 Universit\u00e4tsmedizin Berlin, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henrik","family":"Walter","sequence":"additional","affiliation":[{"name":"Physikalisch-Technische Bundesanstalt, Braunschweig and Berlin, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Whelan","sequence":"additional","affiliation":[{"name":"School of Psychology and Global Brain Health Institute, Trinity College Dublin, Dublin, Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gunter","family":"Schumann","sequence":"additional","affiliation":[{"name":"Centre for Population Neuroscience and Stratified Medicine, Department of Psychiatry and Psychotherapy, Charit\u00e9 Universit\u00e4tsmedizin Berlin, Germany"},{"name":"Centre for Population Neuroscience and Precision Medicine, Institute for Science and Technology of Brain-inspired Intelligence, Fudan University, Shanghai, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hugh","family":"Garavan","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, University of Vermont, Burlington"},{"name":"Department of Psychology, University of Vermont, Burlington"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"10","reference":[{"issue":"8","key":"yoi230064r1","doi-asserted-by":"publisher","first-page":"760","DOI":"10.1016\/S2215-0366(16)00104-8","article-title":"Neurobiology of addiction: a neurocircuitry analysis.","volume":"3","author":"Koob","year":"2016","journal-title":"Lancet Psychiatry"},{"issue":"8","key":"yoi230064r2","doi-asserted-by":"publisher","first-page":"749","DOI":"10.1001\/jamapsychiatry.2022.1652","article-title":"Preaddiction\u2014a missing concept for treating substance use disorders.","volume":"79","author":"McLellan","year":"2022","journal-title":"JAMA Psychiatry"},{"issue":"1","key":"yoi230064r3","doi-asserted-by":"publisher","first-page":"07","DOI":"10.35946\/arcr.v42.1.07","article-title":"Alcohol and the adolescent brain: what we\u2019ve learned and where the data are taking us.","volume":"42","author":"Tapert","year":"2022","journal-title":"Alcohol Res"},{"issue":"6","key":"yoi230064r4","doi-asserted-by":"publisher","first-page":"1335","DOI":"10.1016\/j.neuron.2014.08.050","article-title":"Unraveling the miswired connectome: a developmental perspective.","volume":"83","author":"Di Martino","year":"2014","journal-title":"Neuron"},{"key":"yoi230064r5","article-title":"Application of Research Domain Criteria to childhood and adolescent impulsive and addictive disorders: implications for treatment.","author":"Yip","year":"2016","journal-title":"Clin Psychol Rev"},{"key":"yoi230064r6","doi-asserted-by":"publisher","first-page":"223","DOI":"10.1016\/j.dcn.2018.03.003","article-title":"The development of functional network organization in early childhood and early adolescence: a resting-state fNIRS study.","volume":"30","author":"Cai","year":"2018","journal-title":"Dev Cogn Neurosci"},{"key":"yoi230064r7","doi-asserted-by":"publisher","first-page":"76","DOI":"10.1016\/j.dcn.2013.11.004","article-title":"Topological organization of the human brain functional connectome across the lifespan.","volume":"7","author":"Cao","year":"2014","journal-title":"Dev Cogn Neurosci"},{"issue":"2","key":"yoi230064r8","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0055347","article-title":"Topological organization of functional brain networks in healthy children: differences in relation to age, sex, and intelligence.","volume":"8","author":"Wu","year":"2013","journal-title":"PLoS One"},{"issue":"10","key":"yoi230064r9","doi-asserted-by":"publisher","first-page":"861","DOI":"10.1038\/13158","article-title":"Brain development during childhood and adolescence: a longitudinal MRI study.","volume":"2","author":"Giedd","year":"1999","journal-title":"Nat Neurosci"},{"issue":"1","key":"yoi230064r10","doi-asserted-by":"publisher","first-page":"71","DOI":"10.1038\/s41386-018-0111-z","article-title":"Sex differences in the developing brain: insights from multimodal neuroimaging.","volume":"44","author":"Kaczkurkin","year":"2019","journal-title":"Neuropsychopharmacology"},{"issue":"4","key":"yoi230064r11","doi-asserted-by":"publisher","first-page":"1065","DOI":"10.1016\/j.neuroimage.2007.03.053","article-title":"Sexual dimorphism of brain developmental trajectories during childhood and adolescence.","volume":"36","author":"Lenroot","year":"2007","journal-title":"Neuroimage"},{"issue":"2","key":"yoi230064r12","doi-asserted-by":"publisher","first-page":"01","DOI":"10.35946\/arcr.v40.2.01","article-title":"Gender differences in the epidemiology of alcohol use and related harms in the United States.","volume":"40","author":"White","year":"2020","journal-title":"Alcohol Res"},{"key":"yoi230064r13","doi-asserted-by":"publisher","first-page":"6","DOI":"10.3389\/neuro.09.006.2010","article-title":"Adolescent development of the reward system.","volume":"4","author":"Galvan","year":"2010","journal-title":"Front Hum Neurosci"},{"issue":"9","key":"yoi230064r14","doi-asserted-by":"publisher","first-page":"636","DOI":"10.1038\/nrn3313","article-title":"Understanding adolescence as a period of social-affective engagement and goal flexibility.","volume":"13","author":"Crone","year":"2012","journal-title":"Nat Rev Neurosci"},{"key":"yoi230064r15","doi-asserted-by":"publisher","first-page":"295","DOI":"10.1146\/psych.2015.66.issue-1","article-title":"Beyond simple models of self-control to circuit-based accounts of adolescent behavior.","volume":"66","author":"Casey","year":"2015","journal-title":"Annu Rev Psychol"},{"issue":"25","key":"yoi230064r16","doi-asserted-by":"publisher","first-page":"6885","DOI":"10.1523\/JNEUROSCI.1062-06.2006","article-title":"Earlier development of the accumbens relative to orbitofrontal cortex might underlie risk-taking behavior in adolescents.","volume":"26","author":"Galvan","year":"2006","journal-title":"J Neurosci"},{"issue":"2","key":"yoi230064r17","doi-asserted-by":"publisher","first-page":"243","DOI":"10.1016\/j.conb.2007.02.005","article-title":"Neurodevelopmental changes in working memory and cognitive control.","volume":"17","author":"Bunge","year":"2007","journal-title":"Curr Opin Neurobiol"},{"issue":"12","key":"yoi230064r18","doi-asserted-by":"publisher","first-page":"1128","DOI":"10.1038\/mp.2010.4","article-title":"The IMAGEN study: reinforcement-related behaviour in normal brain function and psychopathology.","volume":"15","author":"Schumann","year":"2010","journal-title":"Mol Psychiatry"},{"issue":"11","key":"yoi230064r19","doi-asserted-by":"publisher","first-page":"1664","DOI":"10.1038\/nn.4135","article-title":"Functional connectome fingerprinting: identifying individuals using patterns of brain connectivity.","volume":"18","author":"Finn","year":"2015","journal-title":"Nat Neurosci"},{"key":"yoi230064r20","doi-asserted-by":"publisher","first-page":"676","DOI":"10.1016\/j.neuroimage.2019.02.002","article-title":"The individual functional connectome is unique and stable over months to years.","volume":"189","author":"Horien","year":"2019","journal-title":"Neuroimage"},{"key":"yoi230064r21","doi-asserted-by":"publisher","first-page":"140","DOI":"10.1016\/j.neuroimage.2017.03.064","article-title":"Can brain state be manipulated to emphasize individual differences in functional connectivity?","volume":"160","author":"Finn","year":"2017","journal-title":"Neuroimage"},{"issue":"8","key":"yoi230064r22","doi-asserted-by":"publisher","first-page":"4383","DOI":"10.1038\/s41380-019-0586-y","article-title":"Dissociable neural substrates of opioid and cocaine use identified via connectome-based modelling.","volume":"26","author":"Lichenstein","year":"2021","journal-title":"Mol Psychiatry"},{"issue":"6","key":"yoi230064r23","doi-asserted-by":"publisher","first-page":"791","DOI":"10.1111\/add.1993.88.issue-6","article-title":"Development of the Alcohol Use Disorders Identification Test (AUDIT): WHO collaborative project on early detection of persons with harmful alcohol consumption\u2013II.","volume":"88","author":"Saunders","year":"1993","journal-title":"Addiction"},{"issue":"1","key":"yoi230064r24","doi-asserted-by":"publisher","first-page":"20","DOI":"10.1006\/nimg.2000.0593","article-title":"fMRI visualization of brain activity during a monetary incentive delay task.","volume":"12","author":"Knutson","year":"2000","journal-title":"Neuroimage"},{"issue":"1","key":"yoi230064r25","doi-asserted-by":"publisher","first-page":"178","DOI":"10.1093\/cercor\/bhm044","article-title":"Stop-signal reaction-time task performance: role of prefrontal cortex and subthalamic nucleus.","volume":"18","author":"Eagle","year":"2008","journal-title":"Cereb Cortex"},{"issue":"3","key":"yoi230064r26","doi-asserted-by":"publisher","first-page":"506","DOI":"10.1038\/nprot.2016.178","article-title":"Using connectome-based predictive modeling to predict individual behavior from brain connectivity.","volume":"12","author":"Shen","year":"2017","journal-title":"Nat Protoc"},{"issue":"12","key":"yoi230064r27","doi-asserted-by":"publisher","first-page":"3413","DOI":"10.1038\/s41380-019-0481-6","article-title":"Prediction of neurocognition in youth from resting state fMRI.","volume":"25","author":"Sripada","year":"2020","journal-title":"Mol Psychiatry"},{"issue":"8","key":"yoi230064r28","doi-asserted-by":"publisher","first-page":"748","DOI":"10.1016\/j.bpsc.2019.11.001","article-title":"Toward addiction prediction: an overview of cross-validated predictive modeling findings and considerations for future neuroimaging research.","volume":"5","author":"Yip","year":"2020","journal-title":"Biol Psychiatry Cogn Neurosci Neuroimaging"},{"issue":"6","key":"yoi230064r30","doi-asserted-by":"publisher","first-page":"1637","DOI":"10.1038\/npp.2015.332","article-title":"A preliminary prospective study of an escalation in \u2018maximum daily drinks\u2019, fronto-parietal circuitry and impulsivity-related domains in young adult drinkers.","volume":"41","author":"Worhunsky","year":"2016","journal-title":"Neuropsychopharmacology"},{"issue":"7","key":"yoi230064r31","doi-asserted-by":"publisher","first-page":"610","DOI":"10.1016\/j.bpsc.2018.02.006","article-title":"Longitudinal effects of alcohol consumption on the hippocampus and parahippocampus in college students.","volume":"3","author":"Meda","year":"2018","journal-title":"Biol Psychiatry Cogn Neurosci Neuroimaging"},{"issue":"7","key":"yoi230064r32","doi-asserted-by":"publisher","first-page":"632","DOI":"10.1016\/j.biopsych.2019.08.026","article-title":"Disturbed cerebellar growth trajectories in adolescents who initiate alcohol drinking.","volume":"87","author":"Sullivan","year":"2020","journal-title":"Biol Psychiatry"},{"issue":"1-2","key":"yoi230064r33","first-page":"127","article-title":"Alcohol\u2019s effects on brain and behavior.","volume":"33","author":"Sullivan","year":"2010","journal-title":"Alcohol Res Health"},{"issue":"8","key":"yoi230064r34","doi-asserted-by":"publisher","first-page":"1185","DOI":"10.1038\/mp.2016.25","article-title":"Alcohol affects brain functional connectivity and its coupling with behavior: greater effects in male heavy drinkers.","volume":"22","author":"Shokri-Kojori","year":"2017","journal-title":"Mol Psychiatry"},{"issue":"11","key":"yoi230064r35","doi-asserted-by":"publisher","first-page":"2077","DOI":"10.1002\/jnr.v100.11","article-title":"Alcohol use disorder-associated structural and functional characteristics of the insula.","volume":"100","author":"Manuweera","year":"2022","journal-title":"J Neurosci Res"},{"issue":"8","key":"yoi230064r36","doi-asserted-by":"publisher","first-page":"805","DOI":"10.1016\/j.bpsc.2022.02.010","article-title":"High-risk drinkers engage distinct stress-predictive brain networks.","volume":"7","author":"Goldfarb","year":"2022","journal-title":"Biol Psychiatry Cogn Neurosci Neuroimaging"},{"issue":"2","key":"yoi230064r37","doi-asserted-by":"publisher","first-page":"215","DOI":"10.1016\/j.bbr.2009.09.015","article-title":"Sensory and motor aspects of addiction.","volume":"207","author":"Yalachkov","year":"2010","journal-title":"Behav Brain Res"},{"issue":"1","key":"yoi230064r38","doi-asserted-by":"publisher","first-page":"2807","DOI":"10.1038\/s41467-018-04920-3","article-title":"Task-induced brain state manipulation improves prediction of individual traits.","volume":"9","author":"Greene","year":"2018","journal-title":"Nat Commun"},{"issue":"5","key":"yoi230064r39","doi-asserted-by":"publisher","first-page":"1979","DOI":"10.1007\/s11682-019-00146-z","article-title":"Multimodal data revealed different neurobiological correlates of intelligence between males and females.","volume":"14","author":"Jiang","year":"2020","journal-title":"Brain Imaging Behav"},{"issue":"4","key":"yoi230064r40","doi-asserted-by":"publisher","first-page":"363","DOI":"10.1056\/NEJMra1511480","article-title":"Neurobiologic advances from the brain disease model of addiction.","volume":"374","author":"Volkow","year":"2016","journal-title":"N Engl J Med"},{"key":"yoi230064r29","unstructured":"NeuroImaging Tools & Resources Collabotory. Accessed August 2, 2023. https:\/\/www.nitrc.org\/frs\/download.php\/13635\/yip_jama_psych.zip"}],"container-title":["JAMA Psychiatry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/jamanetwork.com\/journals\/jamapsychiatry\/articlepdf\/2808724\/jamapsychiatry_yip_2023_oi_230064_1698770477.86364.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T12:27:37Z","timestamp":1698841657000},"score":1,"resource":{"primary":{"URL":"https:\/\/jamanetwork.com\/journals\/jamapsychiatry\/fullarticle\/2808724"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,11,1]]},"references-count":40,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2023,11,1]]}},"URL":"https:\/\/doi.org\/10.1001\/jamapsychiatry.2023.2949","relation":{},"ISSN":["2168-622X"],"issn-type":[{"value":"2168-622X","type":"print"}],"subject":[],"published":{"date-parts":[[2023,11,1]]}}}