{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T05:52:17Z","timestamp":1792561937591,"version":"4.5.0"},"reference-count":47,"publisher":"American Medical Association (AMA)","issue":"12","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JAMA Surg"],"published-print":{"date-parts":[[2025,12,1]]},"abstract":"<jats:sec id=\"ab-ssc250003-1\">\n                    <jats:title>Importance<\/jats:title>\n                    <jats:p>Many patients are diagnosed with benign breast lesions; however, evidence- and consensus-based guidelines for the management of benign breast disease (BBD) are limited.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"ab-ssc250003-2\">\n                    <jats:title>Observations<\/jats:title>\n                    <jats:p>The American Society of Breast Surgeons (ASBrS) and the Society of Breast Imaging (SBI) developed guidelines for the management of benign fibroepithelial lesions (FELs) using a modified Delphi consensus methodology and public comment. There was strong consensus that core biopsy\u2013proven concordant fibroadenomas without atypia only require excision if they were symptomatic, patient preferred, attained a certain size, or demonstrated substantive growth over time on clinical examination. There was strong consensus that when removing a fibroadenoma, complete excision without transection of the mass is recommended and surgeons should consider aesthetics, sensation, and other factors when selecting incision placement. Patients with core biopsy\u2013proven concordant fibroadenomas do not require imaging follow-up and may return to age-appropriate screening. Many benign phyllodes tumors (BPTs) present as an FEL on core biopsy, and these lesions along with any lesions with suspicion of or concern for phyllodes tumors (PTs) require surgical excisional biopsy with complete excision of the mass. Re-excision of a BPT is not required for patients with a positive margin for BPT, but a margin re-excision may be considered if the mass was transected or there is concern of residual disease after excisional biopsy. Patients with BPT who have undergone excision do not require follow-up imaging and may return to age-appropriate screening.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"ab-ssc250003-3\">\n                    <jats:title>Conclusions and Relevance<\/jats:title>\n                    <jats:p>Evidence-informed, consensus and expert opinion-based guidelines for the management of benign FELs of the breast were developed. These guidelines provide clarification on the controversial management of benign FELs of the breast. Any practicing clinicians who treat patients with benign FELs should integrate these guidelines into treatment of their patients.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1001\/jamasurg.2025.4392","type":"journal-article","created":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T15:31:23Z","timestamp":1761147083000},"page":"1378","source":"Crossref","is-referenced-by-count":15,"title":["American Society of Breast Surgeons and Society of Breast Imaging 2025 Guidelines for the Management of Benign Breast Fibroepithelial Lesions"],"prefix":"10.1001","volume":"160","author":[{"given":"Laura H.","family":"Rosenberger","sequence":"first","affiliation":[{"name":"Department of Surgery, Duke University Health System, Durham, North Carolina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard L.","family":"White","sequence":"additional","affiliation":[{"name":"Department of Surgery, Atrium Health Levine Cancer Institute, Charlotte, North 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