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Included are a single allergen inhalation in monkeys to model acute asthmatic episodes, repeated allergen inhalations in monkeys to model chronic asthma, and a lower\u2010respiratory viral infection in mice to model acute and chronic viral alveolitis and bronchitis. In each case, alterations in lung functions believed to correlate with symptoms of the respective disease are measured along with pulmonary inflammation.<\/jats:p>","DOI":"10.1002\/0471141755.ph0502s00","type":"journal-article","created":{"date-parts":[[2004,6,9]],"date-time":"2004-06-09T15:13:09Z","timestamp":1086793989000},"source":"Crossref","is-referenced-by-count":0,"title":["Models of Pulmonary Disease: Acute and Chronic Allergic Asthma in the Monkey and Acute and Chronic Viral Pulmonitis in the Mouse"],"prefix":"10.1002","volume":"00","author":[{"given":"Craig D.","family":"Wegner","sequence":"first","affiliation":[{"name":"Abbott Laboratories  Abott Park Illinois"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Shaughnessy","sequence":"additional","affiliation":[{"name":"Abbott Laboratories  Abott Park Illinois"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Donna","family":"Mussatto","sequence":"additional","affiliation":[{"name":"Abbott Laboratories  Abott Park Illinois"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2001,5]]},"reference":[{"key":"e_1_2_9_1_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/0091-6749(83)90069-6"},{"key":"e_1_2_9_1_3_1","first-page":"389","article-title":"State of the art: Bronchial hyperreactivity","volume":"121","author":"Boushey H.A.","year":"1980","journal-title":"Am. 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