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Detailed materials and methods required for the purification of both PLP and MBP are also described. Modifications of the specified protocols may be necessary for efficient induction of active or adoptive EAE in other mouse strains.<\/jats:p>","DOI":"10.1002\/0471142735.im1501s77","type":"journal-article","created":{"date-parts":[[2007,5,30]],"date-time":"2007-05-30T10:52:26Z","timestamp":1180522346000},"source":"Crossref","is-referenced-by-count":132,"title":["Experimental Autoimmune Encephalomyelitis in the Mouse"],"prefix":"10.1002","volume":"77","author":[{"given":"Stephen D.","family":"Miller","sequence":"first","affiliation":[{"name":"Northwestern University  Chicago Illinois"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William J.","family":"Karpus","sequence":"additional","affiliation":[{"name":"Northwestern University  Chicago Illinois"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2007,5,15]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.153.10.4349"},{"key":"e_1_2_8_3_1","first-page":"316","article-title":"Genetics of experimental autoimmune encephalomyelitis in the mouse","volume":"52","author":"Andersson A.","year":"2004","journal-title":"Arch. 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