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Detailed materials and methods required for the purification of both PLP and MBP are also described. Modifications of the specified protocols may be necessary for efficient induction of active or adoptive EAE in other mouse strains.<\/jats:p>","DOI":"10.1002\/0471142735.im1502s19","type":"journal-article","created":{"date-parts":[[2004,6,9]],"date-time":"2004-06-09T15:13:09Z","timestamp":1086793989000},"source":"Crossref","is-referenced-by-count":2,"title":["Experimental Autoimmune Encephalomyelitis in the Rat"],"prefix":"10.1002","volume":"19","author":[{"given":"Robert H.","family":"Swanborg","sequence":"first","affiliation":[{"name":"Wayne State University School of Medicine  Detroit Michigan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jolie A.","family":"Stepaniak","sequence":"additional","affiliation":[{"name":"Wayne State University School of Medicine  Detroit Michigan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2001,5,15]]},"reference":[{"key":"e_1_2_9_1_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/eji.1830110307"},{"key":"e_1_2_9_1_3_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.169.1.27"},{"key":"e_1_2_9_1_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/eji.1830190210"},{"key":"e_1_2_9_1_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(18)55985-8"},{"key":"e_1_2_9_1_6_1","doi-asserted-by":"publisher","DOI":"10.1080\/00327487208061467"},{"key":"e_1_2_9_1_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/0165-5728(94)90240-2"},{"key":"e_1_2_9_1_8_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.67639"},{"key":"e_1_2_9_1_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/eji.1830120519"},{"key":"e_1_2_9_1_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.1965.tb20200.x"},{"key":"e_1_2_9_1_11_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.153.2.841"},{"key":"e_1_2_9_1_12_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.82.16.5515"},{"key":"e_1_2_9_1_13_1","doi-asserted-by":"crossref","first-page":"1132","DOI":"10.4049\/jimmunol.140.4.1132","article-title":"Antigen\u2010specific inhibition of immune interferon production by suppressor cells of autoimmune encephalomyelitis","volume":"140","author":"McDonald A.H.","year":"1988","journal-title":"J. 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