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The three major schistosomes infecting humans are <jats:italic>Schistosoma mansoni, S. japonicum<\/jats:italic>, and <jats:italic>S. haematobium<\/jats:italic>. Much immunological research has focused on schistosomiasis because of the pathological effects of the disease, which include liver fibrosis and bladder dysfunction. This unit covers a wide range of aspects with respect to maintaining the life cycles of these parasites, including preparation of schistosome egg antigen, maintenance of intermediate snail hosts, infection of the definitive and intermediate hosts, and others. The unit primarily focuses on <jats:italic>S. mansoni<\/jats:italic>, but also includes coverage of <jats:italic>S. japonicum<\/jats:italic> and <jats:italic>S. haematobium<\/jats:italic> life cycles. <jats:italic>Curr. Protoc. Immunol<\/jats:italic>. 103:19.1.1\u201019.1.58. \u00a9 2013 by John Wiley &amp; Sons, Inc.<\/jats:p>","DOI":"10.1002\/0471142735.im1901s103","type":"journal-article","created":{"date-parts":[[2013,11,19]],"date-time":"2013-11-19T03:01:04Z","timestamp":1384830064000},"source":"Crossref","is-referenced-by-count":115,"title":["Schistosomiasis"],"prefix":"10.1002","volume":"103","author":[{"given":"Matthew S.","family":"Tucker","sequence":"first","affiliation":[{"name":"Biomedical Research Institute  Rockville Maryland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laksiri B.","family":"Karunaratne","sequence":"additional","affiliation":[{"name":"Biomedical Research Institute  Rockville Maryland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fred A.","family":"Lewis","sequence":"additional","affiliation":[{"name":"Biomedical Research Institute  Rockville Maryland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tori C.","family":"Freitas","sequence":"additional","affiliation":[{"name":"Myriad RBM, Inc  Saranac Lake New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yung\u2010san","family":"Liang","sequence":"additional","affiliation":[{"name":"Biomedical Research Institute  Rockville Maryland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,11,18]]},"reference":[{"key":"e_1_2_30_2_1","doi-asserted-by":"publisher","DOI":"10.2307\/3280632"},{"key":"e_1_2_30_3_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.132.3.488"},{"key":"e_1_2_30_4_1","first-page":"13","article-title":"Cultivation of schistosomes and snails for researchers in the United States of America and other countries","volume":"4","author":"Bruce J.I.","year":"1992","journal-title":"J. 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