{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,29]],"date-time":"2025-09-29T20:36:59Z","timestamp":1759178219615,"version":"3.41.2"},"reference-count":17,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2023,10,10]],"date-time":"2023-10-10T00:00:00Z","timestamp":1696896000000},"content-version":"vor","delay-in-days":1378,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2020,12,9]],"date-time":"2020-12-09T00:00:00Z","timestamp":1607472000000},"content-version":"vor","delay-in-days":343,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003478","name":"Ministry of Health, Labour and Welfare","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003478","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001700","name":"Ministry of Education, Culture, Sports, Science and Technology","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001700","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Research Institute of Healthcare Data Science"},{"DOI":"10.13039\/501100003478","name":"Ministry of Health, Labour and Welfare","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003478","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001700","name":"Ministry of Education, Culture, Sports, Science and Technology","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001700","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2020,1,17]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Objectives<\/jats:title>\n                  <jats:p>It is unclear whether mandatory health examination is effective for employees who are already being treated for chronic diseases. We focused on patients being treated for hypertension and evaluated the association between employer-based health examination attendance and diabetes treatment initiation.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>Using a database that stores health insurance claims and health examination results of subscribers enrolled in society-managed health insurance plans in Japan, we identified employees aged 40-59 years who were being treated for hypertension when starting diabetes treatment from April 2012 to December 2016. A case-crossover analysis was conducted using 90, 180, and 270 days prior to diabetes treatment initiation as reference points and 90 days after the mandatory health examination as the exposure period. We conducted a subgroup analysis by hemoglobin A1c (HbA1c) level and frequency of outpatient blood glucose testing before the mandatory health examination.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>We identified 1464 individuals starting treatment for diabetes while on antihypertensive drugs. The overall odds ratio for starting diabetes treatment within 90 days of the health examination was 1.89 (95% confidence interval: 1.70-2.10). The subgroup analysis showed that this odds ratio increased as HbA1c level increased and as blood glucose testing frequency decreased.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>Among employees starting treatment for diabetes while being treated for hypertension, employer-based mandatory health examination attendance was associated with initiation of diabetes treatment. The health examinations may be functioning as a complement to screening in outpatient settings.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1002\/1348-9585.12183","type":"journal-article","created":{"date-parts":[[2020,12,10]],"date-time":"2020-12-10T18:32:57Z","timestamp":1607625177000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Association between mandatory health examination attendance and diabetes treatment initiation among employees being treated for hypertension"],"prefix":"10.1093","volume":"62","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2214-6695","authenticated-orcid":false,"given":"Hayato","family":"Yamana","sequence":"first","affiliation":[{"name":"Department of Health Services Research, Graduate School of Medicine, The University of Tokyo , Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sachiko","family":"Ono","sequence":"additional","affiliation":[{"name":"Department of Eat-loss Medicine, Graduate School of Medicine, The University of Tokyo , Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akira","family":"Okada","sequence":"additional","affiliation":[{"name":"Department of Prevention of Diabetes and Lifestyle-Related Diseases, Graduate School of Medicine, The University of Tokyo , Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Taisuke","family":"Jo","sequence":"additional","affiliation":[{"name":"Department of Health Services Research, Graduate School of Medicine, The University of Tokyo , Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hideo","family":"Yasunaga","sequence":"additional","affiliation":[{"name":"Department of Clinical Epidemiology and Health Economics, School of Public Health, The University of Tokyo , Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2020,12,9]]},"reference":[{"key":"2024071808014850500_joh212183-bib-0001","doi-asserted-by":"crossref","first-page":"434","DOI":"10.2337\/diacare.16.2.434","article-title":"Diabetes, other risk factors, and 12-yr cardiovascular mortality for men screened in the Multiple Risk Factor Intervention Trial","volume":"16","author":"Stamler","year":"1993","journal-title":"Diabetes Care"},{"key":"2024071808014850500_joh212183-bib-0002","doi-asserted-by":"crossref","first-page":"1273","DOI":"10.2337\/dci17-0026","article-title":"Diabetes and hypertension: a position statement by the American Diabetes Association","volume":"40","author":"de Boer","year":"2017","journal-title":"Diabetes Care"},{"key":"2024071808014850500_joh212183-bib-0003","first-page":"e13","article-title":"2017 ACC\/AHA\/AAPA\/ABC\/ACPM\/AGS\/APhA\/ASH\/ASPC\/NMA\/PCNA guideline for the prevention, detection, evaluation, and management of high blood pressure in adults: a report of the American College of Cardiology\/American Heart Association Task Force on Clinical Practice Guidelines","volume":"71","author":"Whelton","year":"2018","journal-title":"Hypertension"},{"key":"2024071808014850500_joh212183-bib-0004","doi-asserted-by":"crossref","first-page":"1319","DOI":"10.1001\/jama.2018.0642","article-title":"Individualizing blood pressure targets for people with diabetes and hypertension: comparing the ADA and the ACC\/AHA recommendations","volume":"319","author":"de Boer","year":"2018","journal-title":"JAMA"},{"key":"2024071808014850500_joh212183-bib-0005","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1136\/bmj.321.7258.412","article-title":"Association of systolic blood pressure with macrovascular and microvascular complications of type 2 diabetes (UKPDS 36): prospective observational study","volume":"321","author":"Adler","year":"2000","journal-title":"BMJ"},{"key":"2024071808014850500_joh212183-bib-0006","first-page":"CD006127","article-title":"Blood pressure control for diabetic retinopathy","volume":"1","author":"Do","year":"2015","journal-title":"Cochrane Database Syst Rev"},{"key":"2024071808014850500_joh212183-bib-0007","doi-asserted-by":"crossref","first-page":"1575","DOI":"10.1056\/NEJMoa1001286","article-title":"Effects of intensive blood-pressure control in type 2 diabetes mellitus","volume":"362","author":"Cushman","year":"2010","journal-title":"N Engl J Med"},{"key":"2024071808014850500_joh212183-bib-0008","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1001\/jama.2014.18574","article-title":"Blood pressure lowering in type 2 diabetes: a systematic review and meta-analysis","volume":"313","author":"Emdin","year":"2015","journal-title":"JAMA"},{"volume-title":"Global Action Plan for the Prevention and Control of Noncommunicable Diseases 2013\u20132020","year":"2013","author":"World Health Organization","key":"2024071808014850500_joh212183-bib-0009"},{"key":"2024071808014850500_joh212183-bib-0010","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1016\/j.ypmed.2010.08.017","article-title":"Participation in health check-ups and mortality using propensity score matched cohort analyses","volume":"51","author":"Hozawa","year":"2010","journal-title":"Prev Med"},{"key":"2024071808014850500_joh212183-bib-0011","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0190862","article-title":"Effectiveness of nationwide screening and lifestyle intervention for abdominal obesity and cardiometabolic risks in Japan: the Metabolic Syndrome and Comprehensive Lifestyle Intervention Study on Nationwide Database in Japan (MetS ACTION-J study)","volume":"13","author":"Nakao","year":"2018","journal-title":"PLoS One"},{"volume-title":"Ministry of Health, Labour and Welfare, Japan. Labour standards","key":"2024071808014850500_joh212183-bib-0012"},{"key":"2024071808014850500_joh212183-bib-0013","doi-asserted-by":"crossref","first-page":"1106","DOI":"10.1016\/S0140-6736(11)60828-3","article-title":"Japanese universal health coverage: evolution, achievements, and challenges","volume":"378","author":"Ikegami","year":"2011","journal-title":"Lancet"},{"key":"2024071808014850500_joh212183-bib-0014","doi-asserted-by":"crossref","first-page":"1174","DOI":"10.1016\/S0140-6736(11)60987-2","article-title":"Cost containment and quality of care in Japan: is there a trade-off?","volume":"378","author":"Hashimoto","year":"2011","journal-title":"Lancet"},{"key":"2024071808014850500_joh212183-bib-0015","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1111\/jdi.12810","article-title":"Japanese Clinical Practice Guideline for Diabetes 2016","volume":"9","author":"Haneda","year":"2018","journal-title":"J Diabetes Investig"},{"key":"2024071808014850500_joh212183-bib-0016","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1038\/hr.2014.20","article-title":"The Japanese Society of Hypertension guidelines for the management of hypertension (JSH 2014)","volume":"37","author":"Shimamoto","year":"2014","journal-title":"Hypertens Res"},{"key":"2024071808014850500_joh212183-bib-0017","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1111\/joim.12186","article-title":"Use of self-controlled designs in pharmacoepidemiology","volume":"275","author":"Hallas","year":"2014","journal-title":"J Intern Med"}],"container-title":["Journal of Occupational Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/1348-9585.12183","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/1348-9585.12183","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/academic.oup.com\/joh\/article-pdf\/62\/1\/e12183\/58562084\/joh212183.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/joh\/article-pdf\/62\/1\/e12183\/58562084\/joh212183.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,7,18]],"date-time":"2024-07-18T08:02:37Z","timestamp":1721289757000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/joh\/article\/doi\/10.1002\/1348-9585.12183\/7249960"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,1]]},"references-count":17,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2020,1,17]]}},"URL":"https:\/\/doi.org\/10.1002\/1348-9585.12183","relation":{},"ISSN":["1341-9145","1348-9585"],"issn-type":[{"type":"print","value":"1341-9145"},{"type":"electronic","value":"1348-9585"}],"subject":[],"published-other":{"date-parts":[[2020,1]]},"published":{"date-parts":[[2020,1]]},"assertion":[{"value":"2020-07-19","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-11-11","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-12-09","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e12183"}}