{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T09:09:02Z","timestamp":1792400942415,"version":"4.4.0"},"reference-count":23,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2023,10,10]],"date-time":"2023-10-10T00:00:00Z","timestamp":1696896000000},"content-version":"vor","delay-in-days":1012,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2021,12,26]],"date-time":"2021-12-26T00:00:00Z","timestamp":1640476800000},"content-version":"vor","delay-in-days":359,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004704","name":"The National Research Council of Thailand","doi-asserted-by":"publisher","award":["NRCT 6100007"],"award-info":[{"award-number":["NRCT 6100007"]}],"id":[{"id":"10.13039\/501100004704","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2021,1,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Objective<\/jats:title>\n                  <jats:p>This study assessed the health risk of benzene exposure among Thai gasoline station workers through biomarker detection and experience of adverse symptoms.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>Trans, trans-muconic acid (tt-MA) metabolites of benzene were analyzed from spot urine sampled among gasoline station workers after shift work using HPLC-UV. Air benzene monitoring was done with an active sampler connected to a charcoal sorbent tube, and analyzed by GC-FID. The health risk was calculated by using the biomatrix of the likelihood of benzene exposure and the severity of adverse symptoms.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>The tt-MA concentration, among 235 workers, ranged from less than 10\u20132159 \u00b5g\/g Cr, which corresponded to the air benzene concentration range of &amp;lt;0.1 to 65.8 ppb. In total, 32.3% of workers had a higher than acceptable risk level and there was a significant association between gasoline station work zones and the likelihood of benzene exposure as well as the health risk of workers. The health risk levels estimated from the biomarker monitoring were consistent with the risk matrix of air benzene monitoring.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>This tt-MA biomarker monitoring and biomatrix of health risk assessment is suggested as useful for health surveillance of gasoline station workers exposed to benzene.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1002\/1348-9585.12307","type":"journal-article","created":{"date-parts":[[2021,12,27]],"date-time":"2021-12-27T07:55:36Z","timestamp":1640591736000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Biomatrix of health risk assessment of benzene-exposed workers at Thai gasoline stations"],"prefix":"10.1093","volume":"63","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4190-4930","authenticated-orcid":false,"given":"Sunisa","family":"Chaiklieng","sequence":"first","affiliation":[{"name":"Department of Environmental Health, Occupational Health and Safety, Faculty of Public Health, Khon Kaen University , Khon Kaen, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pornnapa","family":"Suggaravetsiri","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Biostatistics, Faculty of Public Health, Khon Kaen University , Khon Kaen, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Herman","family":"Autrup","sequence":"additional","affiliation":[{"name":"Institute of Public Health, Aarhus University , Aarhus, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2021,12,26]]},"reference":[{"key":"2024071808213877500_joh212307-bib-0001","volume-title":"IARC Monograph on the evaluation of carcinogen risk to human","author":"International Agency for Research Cancer"},{"key":"2024071808213877500_joh212307-bib-0002","volume-title":"Gasoline stations data","author":"Department of Energy Business, Ministry of Energy, Thailand"},{"issue":"8","key":"2024071808213877500_joh212307-bib-0003","doi-asserted-by":"crossref","first-page":"2213","DOI":"10.1080\/10807039.2015.1044938","article-title":"Benzene exposure at gasoline stations \u2013 health risk assessment","volume":"21","author":"Chaiklieng","year":"2015","journal-title":"Hum Ecol Risk Assess"},{"key":"2024071808213877500_joh212307-bib-0004","first-page":"117","article-title":"Occupational exposure of gasoline station workers to BTEX compounds in Bangkok, Thailand","volume":"3","author":"Tunsaringkarn","year":"2012","journal-title":"IJOEM"},{"key":"2024071808213877500_joh212307-bib-0005","volume-title":"TLVs and BEIs. Based on the documentation of the threshold limit values for chemical substances and physical agents & biological exposure indices","author":"ACGIH","year":"2019"},{"key":"2024071808213877500_joh212307-bib-0006","volume-title":"NIOSH Manual of analytical methods (NMAM)","author":"NIOSH","year":"2016","edition":"5th"},{"key":"2024071808213877500_joh212307-bib-0007","doi-asserted-by":"crossref","first-page":"2545","DOI":"10.3390\/ijerph16142545","article-title":"Risk assessment on benzene exposure among gasoline station workers","volume":"16","author":"Chaiklieng","year":"2019","journal-title":"Int J Environ Res Public Health"},{"key":"2024071808213877500_joh212307-bib-0008","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/j.toxlet.2009.04.028","article-title":"Low air levels of benzene: correlation between biomarkers of exposure and genotoxic effect","volume":"192","author":"Fracasso","year":"2010","journal-title":"Toxicol Lett"},{"key":"2024071808213877500_joh212307-bib-0009","doi-asserted-by":"crossref","first-page":"4209","DOI":"10.3390\/ijerph16214209","article-title":"Factor affecting tt-muconic acid in benzene exposed workers at gasoline stations","volume":"16","author":"Chaiklieng","year":"2019","journal-title":"Int J Environ Res Public Health"},{"issue":"3","key":"2024071808213877500_joh212307-bib-0010","first-page":"13","article-title":"Measuring the amount of trans, trans-muconic acid (t, t-MA) in correlation with the CD4+ and CD8+ lymphocytes and their ratios caused by benzene exposure, and associated occupational health hazards","volume":"8","author":"Sukaisi","year":"2017","journal-title":"IIOABJ"},{"key":"2024071808213877500_joh212307-bib-0011","first-page":"184","article-title":"Human benzene metabolism following occupational and environmental exposures","volume":"19","author":"Rappaport","year":"2010","journal-title":"Chem Biol Interact"},{"issue":"1","key":"2024071808213877500_joh212307-bib-0012","first-page":"26","article-title":"Comparison of benzene exposure among occupations at gasoline service stations in Khon Kaen province","volume":"15","author":"Sonphan","year":"2020","journal-title":"Public Health J Burapha Univ"},{"issue":"11","key":"2024071808213877500_joh212307-bib-0013","doi-asserted-by":"crossref","first-page":"2036","DOI":"10.5958\/0976-5506.2019.03901.9","article-title":"Risk assessment on BTEX exposure at fuel storage tank area in gasoline station","volume":"10","author":"Dacherngkhao","year":"2019","journal-title":"IJPHRD"},{"issue":"3","key":"2024071808213877500_joh212307-bib-0014","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1007\/s00420-009-0469-7","article-title":"The validity of new biomarkers of internal dose for use in the biological monitoring of occupational and environmental exposure to low concentrations of benzene and toluene","volume":"83","author":"Lovreglio","year":"2010","journal-title":"Int Arch Occup Environ Health"},{"issue":"2","key":"2024071808213877500_joh212307-bib-0015","first-page":"62","article-title":"Biological monitoring of petrochemical industry workers exposed to benzene, toluene, xylenes, methyl ethyl ketone, and phenol in southern Iran","volume":"3","author":"Rahimpoor","year":"2015","journal-title":"JOHE"},{"key":"2024071808213877500_joh212307-bib-0016","doi-asserted-by":"crossref","first-page":"S97","DOI":"10.1007\/s00420-002-0388-3","article-title":"Assessment of the correlation between exposure to benzene and urinary excretion of t, t-muconic acid in workers from a petrochemical plant","volume":"75","author":"Panev","year":"2002","journal-title":"Int Arch Occ Environ Health"},{"key":"2024071808213877500_joh212307-bib-0017","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1136\/oem.58.3.165","article-title":"Exposure to benzene in urban workers: environmental and biological monitoring of traffic police in Rome","volume":"58","author":"Crebelli","year":"2001","journal-title":"Occup Environ Med"},{"issue":"7","key":"2024071808213877500_joh212307-bib-0018","doi-asserted-by":"crossref","first-page":"1823","DOI":"10.1080\/10807039.2021.1910010","article-title":"Exposure to benzene and toluene of gasoline station workers in Khon Kaen, Thailand and adverse effects","volume":"27","author":"Chaiklieng","year":"2021","journal-title":"Hum Ecol Risk Assess"},{"key":"2024071808213877500_joh212307-bib-0019","volume-title":"Human health evaluation manual, supplement guidance: Update of standard default exposure factors","author":"United States Environmental Protection Agency (US.EPA)","year":"2009"},{"issue":"2","key":"2024071808213877500_joh212307-bib-0020","doi-asserted-by":"crossref","first-page":"171","DOI":"10.21608\/ejom.2010.720","article-title":"Biological assessment of exposure to benzene among petrol stations\u2019 workers in Zagazig city by using trans, trans-Muconic acid as urinary indicator","volume":"34","author":"Abou El-Magd","year":"2010","journal-title":"Egypt J Occup Med"},{"issue":"4","key":"2024071808213877500_joh212307-bib-0021","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0249913","article-title":"Risk assessment of workers\u2019 exposure to BTEX and hazardous area classification at gasoline stations","volume":"16","author":"Chaiklieng","year":"2021","journal-title":"PLoS One"},{"key":"2024071808213877500_joh212307-bib-0022","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1007\/s11869-015-0349-0","article-title":"Benzene, toluene, ethylbenzene and xylene concentrations in atmospheric ambient air of gasoline and CNG refueling stations","volume":"9","author":"Hazrati","year":"2016","journal-title":"Air Qual Atmos Health"},{"key":"2024071808213877500_joh212307-bib-0023","doi-asserted-by":"crossref","first-page":"117847","DOI":"10.1016\/j.atmosenv.2020.117847","article-title":"Health symptoms associated with occupational exposure of gasoline station workers to BTEX compounds","volume":"241","author":"Al-Harbi","year":"2020","journal-title":"Atmospheric Environment"}],"container-title":["Journal of Occupational Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/1348-9585.12307","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/1348-9585.12307","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/academic.oup.com\/joh\/article-pdf\/63\/1\/e12307\/58562654\/joh212307.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/joh\/article-pdf\/63\/1\/e12307\/58562654\/joh212307.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,7,18]],"date-time":"2024-07-18T08:22:34Z","timestamp":1721290954000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/joh\/article\/doi\/10.1002\/1348-9585.12307\/7249778"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,1]]},"references-count":23,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021,1,10]]}},"URL":"https:\/\/doi.org\/10.1002\/1348-9585.12307","relation":{},"ISSN":["1341-9145","1348-9585"],"issn-type":[{"value":"1341-9145","type":"print"},{"value":"1348-9585","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2021,1]]},"published":{"date-parts":[[2021,1]]},"assertion":[{"value":"2020-12-26","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-12-08","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-12-26","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e12307"}}