{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T19:54:30Z","timestamp":1791316470982,"version":"4.3.1"},"update-to":[{"DOI":"10.1002\/14651858.cd000244","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2010,3,17]],"date-time":"2010-03-17T00:00:00Z","timestamp":1268784000000}}],"reference-count":76,"publisher":"Wiley","issue":"3","content-domain":{"domain":["wiley.com","cochranelibrary.com"],"crossmark-restriction":true},"short-container-title":[],"DOI":"10.1002\/14651858.cd000244.pub2","type":"journal-article","created":{"date-parts":[[2010,6,15]],"date-time":"2010-06-15T11:23:24Z","timestamp":1276601004000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":68,"title":["Antibiotic prophylaxis for surgery for proximal femoral and other closed long bone fractures"],"prefix":"10.1002","volume":"2010","author":[{"given":"William J","family":"Gillespie","sequence":"first","affiliation":[{"name":"University of Hull; Hull York Medical School; Cottingham Road Hull UK HU6 7RX"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Geert HIM","family":"Walenkamp","sequence":"additional","affiliation":[{"name":"Maastricht University Medical Center, Research Institute Caphri; Department of Orthopaedics; Postbus 5800 Maastricht Netherlands 6229 HX"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2010,3,17]]},"reference":[{"issue":"1","key":"10.1002\/14651858.CD000244.pub2-BIB0001|cit1","doi-asserted-by":"crossref","first-page":"57","DOI":"10.3109\/17453678208992179","article-title":"Antibiotic prophylaxis in open and closed fractures: a controlled clinical trial","volume":"53","author":"Bergman","year":"1982","journal-title":"Acta Orthopaedica Scandinavica"},{"issue":"1","key":"10.1002\/14651858.CD000244.pub2-BIB0002|cit2","first-page":"61","article-title":"Antibiotic prophylaxis with two doses of cephalosporin in patients managed with internal fixation for a fracture of the hip","volume":"75","author":"Bodoky","year":"1993","journal-title":"Journal of Bone and Joint Surgery - American Volume"},{"issue":"1-2","key":"10.1002\/14651858.CD000244.pub2-BIB0003|cit3","first-page":"91","article-title":"Preoperative assessment of at-risk patients in traumatology","volume":"56","author":"Bodoky","year":"1989","journal-title":"Helvetica Chirurgica Acta"},{"issue":"9009","key":"10.1002\/14651858.CD000244.pub2-BIB0004|cit4","doi-asserted-by":"crossref","first-page":"1133","DOI":"10.1016\/S0140-6736(96)90606-6","article-title":"Randomised controlled trial of single dose antibiotic prophylaxis in surgical treatment of closed fractures: the Dutch Trauma Trial","volume":"347","author":"Boxma","year":"1996","journal-title":"Lancet"},{"issue":"6","key":"10.1002\/14651858.CD000244.pub2-BIB0005|cit5","first-page":"1251","article-title":"A double-blind clinical trial of prophylactic antibiotics in hip fractures","volume":"55","author":"Boyd","year":"1973","journal-title":"Journal of Bone and Joint Surgery - American Volume"},{"issue":"2","key":"10.1002\/14651858.CD000244.pub2-BIB0006|cit6","first-page":"122","article-title":"Perioperative cefazolin prophylaxis in hip fracture surgery","volume":"33","author":"Buckley","year":"1990","journal-title":"Canadian Journal of Surgery"},{"key":"10.1002\/14651858.CD000244.pub2-BIB0007|cit7","first-page":"343","article-title":"Perioperative cefazolin prophylaxis in hip fracture surgery","volume":"71B","author":"Buckley","year":"1989","journal-title":"Journal of Bone and Joint Surgery -British Volume"},{"key":"10.1002\/14651858.CD000244.pub2-BIB0008|cit8","first-page":"457","article-title":"Prophylactic antibiotics in hip fracture. A double-blind, prospective study","volume":"62","author":"Burnett","year":"1980","journal-title":"Journal of Bone and Joint Surgery - American Volume"},{"key":"10.1002\/14651858.CD000244.pub2-BIB0009|cit9","first-page":"808","article-title":"Cloxacillin in the prophylaxis of post-operative infections of the hip","volume":"55","author":"Ericson","year":"1973","journal-title":"Journal of Bone and Joint Surgery - American Volume"},{"issue":"7","key":"10.1002\/14651858.CD000244.pub2-BIB0010|cit10","first-page":"1044","article-title":"Prophylaxis against infection. Single-dose cefonicid compared with multiple dose cefamandole","volume":"73","author":"Garcia","year":"1991","journal-title":"Journal of Bone and Joint Surgery - American Volume"},{"issue":"8","key":"10.1002\/14651858.CD000244.pub2-BIB0011|cit11","first-page":"1219","article-title":"Prophylactic cefamandole in orthopaedic surgery","volume":"66","author":"Gatell","year":"1984","journal-title":"Journal of Bone and Joint Surgery - American Volume"},{"issue":"8","key":"10.1002\/14651858.CD000244.pub2-BIB0012|cit12","first-page":"1189","article-title":"Perioperative cefamandole prophylaxis against infections","volume":"69","author":"Gatell","year":"1987","journal-title":"Journal of Bone and Joint Surgery - American Volume"},{"issue":"4","key":"10.1002\/14651858.CD000244.pub2-BIB0013|cit13","doi-asserted-by":"crossref","first-page":"361","DOI":"10.3109\/17453678709146355","article-title":"Cefuroxime prophylaxis in trochanteric hip fracture operations","volume":"58","author":"Hedstrom","year":"1987","journal-title":"Acta Orthopaedica Scandinavica"},{"issue":"2","key":"10.1002\/14651858.CD000244.pub2-BIB0014|cit14","doi-asserted-by":"crossref","first-page":"152","DOI":"10.3109\/17453679009006509","article-title":"Antibiotic prophylaxis in surgery for hip fractures","volume":"61","author":"Hjortrup","year":"1990","journal-title":"Acta Orthopaedica Scandinavica"},{"issue":"11","key":"10.1002\/14651858.CD000244.pub2-BIB0015|cit15","first-page":"713","article-title":"Preventive antibiotic treatment in hip fracture surgery","volume":"149","author":"Kjersgaard","year":"1987","journal-title":"Ugeskrift for Laeger"},{"issue":"2","key":"10.1002\/14651858.CD000244.pub2-BIB0016|cit16","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/0020-1383(91)90067-O","article-title":"Is antibiotic prophylaxis necessary for internal fixation of low-energy fractures?","volume":"22","author":"Hughes","year":"1991","journal-title":"Injury"},{"issue":"4","key":"10.1002\/14651858.CD000244.pub2-BIB0017|cit17","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1016\/0002-9610(87)90573-3","article-title":"Antibiotic prophylaxis of 1,036 patients undergoing elective surgical procedures. A prospective, randomized comparative trial of cefazolin, cefoxitin and cefotaxime in a prepaid medical practice","volume":"153","author":"Jones","year":"1987","journal-title":"American Journal of Surgery"},{"issue":"Suppl 2","key":"10.1002\/14651858.CD000244.pub2-BIB0018|cit18","first-page":"573","article-title":"Single dose prophylaxis of ceftriaxone versus standard dosage of cefotaxime in the prophylaxis of bacterial complications in orthopaedic surgery","volume":"6","author":"Karachalios","year":"1987","journal-title":"Chemioterapia"},{"issue":"6","key":"10.1002\/14651858.CD000244.pub2-BIB0019|cit19","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1159\/000238803","article-title":"Antibiotic prophylaxis in the surgical treatment of peritrochanteric fractures: a comparative trial between two cephalosporins","volume":"36","author":"Karachalios","year":"1990","journal-title":"Chemotherapy"},{"issue":"4","key":"10.1002\/14651858.CD000244.pub2-BIB0020|cit20","first-page":"417","article-title":"One dose cefuroxime prophylaxis in hip fracture surgery","volume":"84","author":"Kaukonen","year":"1995","journal-title":"Annales Chirurgica et Gynaecologiae"},{"issue":"2-3","key":"10.1002\/14651858.CD000244.pub2-BIB0021|cit21","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1007\/BF00397958","article-title":"Prophylactic use of cephradine against postoperative infections of petrochanteric fractures","volume":"92","author":"Lindberg","year":"1978","journal-title":"Archives of Orthopaedic & Traumatic Surgery"},{"issue":"2","key":"10.1002\/14651858.CD000244.pub2-BIB0022|cit22","first-page":"125","article-title":"Single dose antibiotic prophylaxis in osteosynthesis for hip fractures. A clinical multicentre study in Finland","volume":"89","author":"L\u00fcthje","year":"2000","journal-title":"Annales Chirurgiae at Gynaecologiae"},{"issue":"2","key":"10.1002\/14651858.CD000244.pub2-BIB0023|cit23","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1016\/0020-1383(90)90065-3","article-title":"Antibiotic prophylaxis in proximal femoral fracture","volume":"21","author":"McQueen","year":"1990","journal-title":"Injury"},{"key":"10.1002\/14651858.CD000244.pub2-BIB0024|cit24","first-page":"184","article-title":"Short-term preventive antibiotics","volume":"(205)","author":"Heydemann","year":"1986","journal-title":"Clinical Orthopaedics & Related Research"},{"key":"10.1002\/14651858.CD000244.pub2-BIB0025|cit25","first-page":"258","article-title":"One day versus seven days of preventive antibiotic therapy in orthopedic surgery","volume":"(176)","author":"Nelson","year":"1983","journal-title":"Clinical Orthopaedics & Related Research"},{"issue":"2","key":"10.1002\/14651858.CD000244.pub2-BIB0026|cit26","doi-asserted-by":"crossref","first-page":"161","DOI":"10.3109\/17453679508995513","article-title":"Bone and wound fluid concentrations of cephalosporins. Oral cefadroxil and parenteral cefuroxime compared in 52 patients with a trochanteric fracture","volume":"66","author":"Nungu","year":"1995","journal-title":"Acta Orthopaedica Scandinavica"},{"issue":"6","key":"10.1002\/14651858.CD000244.pub2-BIB0027|cit27","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1007\/BF00448952","article-title":"Prophylaxis with oral cefadroxil versus intravenous cefuroxime in trochanteric fracture surgery. A clinical multicentre study","volume":"114","author":"Nungu","year":"1995","journal-title":"Archives of Orthopaedic & Trauma Surgery"},{"issue":"1","key":"10.1002\/14651858.CD000244.pub2-BIB0028|cit28","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1097\/00005131-199402000-00014","article-title":"Double-blind randomized prospective study of the efficacy of antibiotic prophylaxis for open reduction and internal fixation of closed ankle fractures","volume":"8","author":"Paiement","year":"1994","journal-title":"Journal of Orthopaedic Trauma"},{"issue":"1","key":"10.1002\/14651858.CD000244.pub2-BIB0029|cit29","first-page":"97","article-title":"Antibiotic prophylaxis in operations on trochanteric femoral fractures","volume":"60","author":"Tengve","year":"1978","journal-title":"Journal of Bone and Joint Surgery - American Volume"},{"issue":"1","key":"10.1002\/14651858.CD000244.pub2-BIB0030|cit30","first-page":"45","article-title":"Role of single dose antibiotic prophylaxis in clean orthopedic surgery","volume":"16","author":"Ali","year":"2006","journal-title":"Journal of the College of Physicians & Surgeons - Pakistan"},{"issue":"1","key":"10.1002\/14651858.CD000244.pub2-BIB0031|cit31","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1097\/00005373-198301000-00005","article-title":"Treatment of open fractures: a prospective study","volume":"23","author":"Benson","year":"1983","journal-title":"Journal of Trauma - Injury Infection & Critical Care"},{"issue":"1","key":"10.1002\/14651858.CD000244.pub2-BIB0032|cit32","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1097\/00005131-198701010-00002","article-title":"A double-blind clinical trial of prophylactic cloxacillin in open fractures","volume":"1","author":"Braun","year":"1987","journal-title":"Journal of Orthopaedic Trauma"},{"issue":"4","key":"10.1002\/14651858.CD000244.pub2-BIB0033|cit33","first-page":"357","article-title":"Antimicrobial chemoprophylaxis with ceftriaxone in surgical implantation of a non-cemented hip prosthesis: comparison of 2 dosage schemes","volume":"73","author":"Centulio","year":"1988","journal-title":"Chirurgia Degli Organi di Movimento"},{"issue":"Suppl 3","key":"10.1002\/14651858.CD000244.pub2-BIB0034|cit34","first-page":"230","article-title":"A prospective randomized study on four regimes of antibiotic prophylaxis for hip fracture operations","volume":"75B","author":"Chiu","year":"1993","journal-title":"Journal of Bone and Joint Surgery - British Volume"},{"issue":"1","key":"10.1002\/14651858.CD000244.pub2-BIB0035|cit35","first-page":"23","article-title":"Perioperative antibioticotherapy in the prevention of infection in bone surgery","volume":"22","author":"Silva","year":"1987","journal-title":"Revista Brasileira de Ortopedia"},{"issue":"4","key":"10.1002\/14651858.CD000244.pub2-BIB0036|cit36","doi-asserted-by":"crossref","first-page":"901","DOI":"10.1093\/clinids\/6.Supplement_4.S901","article-title":"A double-blind study comparing cefonicid with cefazolin as prophylaxis in patients undergoing total hip or knee replacement","volume":"6","author":"Benedictis","year":"1984","journal-title":"Reviews of Infectious Diseases"},{"issue":"3","key":"10.1002\/14651858.CD000244.pub2-BIB0037|cit37","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1001\/archsurg.1988.01400270067010","article-title":"Duration of preventive antibiotic administration for open extremity fractures","volume":"123","author":"Dellinger","year":"1988","journal-title":"Archives of Surgery"},{"issue":"1","key":"10.1002\/14651858.CD000244.pub2-BIB0038|cit38","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1007\/BF00265744","article-title":"Two day cefamandole versus five-day cephazolin prophylaxis in 965 total hip replacements. Report of a multicentre double blind randomised trial","volume":"12","author":"Evrard","year":"1988","journal-title":"International Orthopaedics"},{"issue":"Suppl 2","key":"10.1002\/14651858.CD000244.pub2-BIB0039|cit39","first-page":"34","article-title":"Antimicrobial prophylaxis with ceftizoxime versus cefuroxime in orthopedic surgery. Ceftizoxime Orthopedic Surgery Italian Study Group","volume":"3","author":"Garotta","year":"1991","journal-title":"Journal of Chemotherapy."},{"issue":"5 Pt 2","key":"10.1002\/14651858.CD000244.pub2-BIB0040|cit40","first-page":"567","article-title":"Prophylactic antibiotic therapy with cefamandole in total hip surgery replacement using Charnley's tent. A randomized study","volume":"32","author":"Gunst","year":"1984","journal-title":"Pathologie Biologie"},{"key":"10.1002\/14651858.CD000244.pub2-BIB0041|cit41","first-page":"249","article-title":"Prophylaxis with cefamandole nafate in elective orthopaedic surgery","volume":"(209)","author":"Henley","year":"1986","journal-title":"Clinical Orthopaedics & Related Research"},{"issue":"8224","key":"10.1002\/14651858.CD000244.pub2-BIB0042|cit42","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1016\/S0140-6736(81)92678-7","article-title":"Prophylactic cefazolin versus placebo in total hip replacement. Report of a multicentre double-blind randomised trial","volume":"1","author":"Hill","year":"1981","journal-title":"Lancet"},{"issue":"3","key":"10.1002\/14651858.CD000244.pub2-BIB0043|cit43","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1097\/00005131-198802030-00001","article-title":"Severe open tibial fractures: a study protocol","volume":"2","author":"Johnson","year":"1988","journal-title":"Journal of Orthopaedic Trauma"},{"issue":"6","key":"10.1002\/14651858.CD000244.pub2-BIB0044|cit44","first-page":"921","article-title":"Cephalosporins for prophylaxis in operative repair of femoral fractures. Levels in serum, muscle, and hematoma","volume":"67","author":"Jones","year":"1985","journal-title":"Journal of Bone and Joint Surgery - American Volume"},{"issue":"4","key":"10.1002\/14651858.CD000244.pub2-BIB0045|cit45","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1016\/0732-8893(87)90183-0","article-title":"Single-dose cephalosporin prophylaxis of 929 surgical procedures in a prepaid group practice: a prospective randomized comparison of cefoperazone and cefotaxime","volume":"6","author":"Jones","year":"1987","journal-title":"Diagnostic Microbiology & Infectious Disease"},{"issue":"8","key":"10.1002\/14651858.CD000244.pub2-BIB0046|cit46","first-page":"1167","article-title":"Comparison of intravenous and oral antibiotic therapy in the treatment of fractures caused by low-velocity gunshots. A prospective, randomized study of infection rates","volume":"78","author":"Knapp","year":"1996","journal-title":"Journal of Bone and Joint Surgery - American Volume"},{"issue":"3","key":"10.1002\/14651858.CD000244.pub2-BIB0047|cit47","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1017\/S0022172400065098","article-title":"Infection and sepsis after operations for total hip of knee-joint replacement: influence of ultraclean air, prophylactic antibiotics and other factors","volume":"93","author":"Lidwell","year":"1984","journal-title":"Journal of Hygiene"},{"issue":"1","key":"10.1002\/14651858.CD000244.pub2-BIB0048|cit48","first-page":"62","article-title":"A double-blinded, randomized, controlled clinical trial to compare cefazolin and cefonicid for antimicrobial prophylaxis in clean orthopedic surgery","volume":"31","author":"Liebergall","year":"1995","journal-title":"Israel Journal of Medical Science"},{"issue":"1","key":"10.1002\/14651858.CD000244.pub2-BIB0049|cit49","first-page":"39","article-title":"Prophylaxis against infection in total joint arthroplasty. One day of cefuroxime compared with three days of cefazolin","volume":"76","author":"Mauerhan","year":"1994","journal-title":"Journal of Bone and Joint Surgery - American Volume"},{"key":"10.1002\/14651858.CD000244.pub2-BIB0050|cit50","first-page":"19","article-title":"Teicoplanin vs cephamandole for antimicrobial prophylaxis in prosthetic joint implant surgery; preliminary results","volume":"(567)","author":"Mollan","year":"1992","journal-title":"European Journal of Surgery. Supplement"},{"issue":"Suppl 1","key":"10.1002\/14651858.CD000244.pub2-BIB0051|cit51","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1097\/00007611-197710001-00013","article-title":"Antibiotic and bacteriologic considerations in open fractures","volume":"70","author":"Patzakis","year":"1977","journal-title":"Southern Medical Journal"},{"issue":"4","key":"10.1002\/14651858.CD000244.pub2-BIB0052|cit52","first-page":"777","article-title":"Prophylactic antibiotics in clean orthopaedic surgery","volume":"56","author":"Pavel","year":"1974","journal-title":"Journal of Bone and Joint Surgery - American Volume"},{"issue":"Suppl 1","key":"10.1002\/14651858.CD000244.pub2-BIB0053|cit53","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1097\/00007611-197710001-00015","article-title":"Prophylactic antibiotics in elective orthopedic surgery: a prospective study of 1,591 cases","volume":"70","author":"Pavel","year":"1977","journal-title":"Southern Medical Journal"},{"issue":"Suppl 1","key":"10.1002\/14651858.CD000244.pub2-BIB0054|cit54","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1159\/000129056","article-title":"Ceftriaxone as short-term antimicrobial chemoprophylaxis in orthopedic surgery: a 1-year multicenter follow-up. Preliminary results of a controlled multicentre study","volume":"21","author":"Periti","year":"1989","journal-title":"European Surgical Research"},{"key":"10.1002\/14651858.CD000244.pub2-BIB0055|cit55","first-page":"3","article-title":"Teicoplanin- its role in systemic therapy of burns infections and as prophylaxis for orthopaedic surgery. Italian Study Groups for Antimicrobial Prophylaxis in Orthopaedic Surgery and Burns","volume":"(567)","author":"Periti","year":"1992","journal-title":"European Journal of Surgery, Acta Chirurgica, Supplement"},{"issue":"6165","key":"10.1002\/14651858.CD000244.pub2-BIB0056|cit56","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1136\/bmj.1.6165.707","article-title":"Antibiotic prophylaxis in total hip replacement","volume":"1","author":"Pollard","year":"1979","journal-title":"British Medical Journal"},{"issue":"2","key":"10.1002\/14651858.CD000244.pub2-BIB0057|cit57","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1007\/BF00433285","article-title":"The prophylactic use of antibiotics in alloarthroplasty of the hip joint for coxarthrosis","volume":"96","author":"Schulitz","year":"1980","journal-title":"Archives of Orthopaedic & Traumatic Surgery"},{"issue":"4","key":"10.1002\/14651858.CD000244.pub2-BIB0058|cit58","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1007\/BF00449674","article-title":"Cefamandole and isoxazolyl penicillins in antibiotic prophylaxis of patients undergoing total hip or knee-joint arthroplasty","volume":"107","author":"Vainionpaa","year":"1988","journal-title":"Archives of Orthopaedic & Traumatic Surgery"},{"issue":"5","key":"10.1002\/14651858.CD000244.pub2-BIB0059|cit59","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1007\/BF00932321","article-title":"Flucloxacillin compared with cefazolin in short-term prophylaxis for clean orthopedic surgery","volume":"108","author":"Meirhaeghe","year":"1989","journal-title":"Archives of Orthopaedic & Trauma Surgery"},{"issue":"1","key":"10.1002\/14651858.CD000244.pub2-BIB0060|cit60","first-page":"58","article-title":"A comparison of dicloxacillin and ampicillin in the antibiotic prophylaxis of total hip replacement","volume":"65","author":"Visuri","year":"1976","journal-title":"Annales Chirurgiae et Gynaecologiae"},{"issue":"1","key":"10.1002\/14651858.CD000244.pub2-BIB0061|cit61","doi-asserted-by":"crossref","first-page":"19","DOI":"10.3109\/17453679209154842","article-title":"Cefuroxime for prevention of post-operative coxitis. One versus three doses tested in a randomized multicenter study of 2651 arthroplasties","volume":"63","author":"Wymenga","year":"1992","journal-title":"Acta Orthopaedica Scandinavica"},{"key":"10.1002\/14651858.CD000244.pub2-BIB0062|cit62","unstructured":"Davey P Randomised trial of extended antibiotic prophylaxis for fracture fixation and joint replacement: clinical benefits versus ecological risks http:\/\/isrctn.org\/ISRCTN75423827"},{"key":"10.1002\/14651858.CD000244.pub2-BIB0063|cit63","unstructured":"Greenberg DD Anderson LK Antibiotic prophylaxis in orthopaedic traumatology: a prospective, randomized trial of duration of administration http:\/\/clinicaltrials.gov\/show\/NCT00610987"},{"issue":"12","key":"10.1002\/14651858.CD000244.pub2-BIB0064|cit64","first-page":"625","article-title":"Cost effectiveness of antibiotic prophylaxis for closed fractures","volume":"97","author":"Albers","year":"1994","journal-title":"Unfallchirurgie"},{"key":"10.1002\/14651858.CD000244.pub2-BIB0065|cit65","first-page":"161","article-title":"The effective period of preventive antibiotic action in experimental incisions and dermal lesions","volume":"50","author":"Burke","year":"1961","journal-title":"Surgery"},{"issue":"1","key":"10.1002\/14651858.CD000244.pub2-BIB0066|cit66","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3310\/hta12010","article-title":"A systematic review and economic model of switching from non-glycopeptide to glycopeptide antibiotic prophylaxis for surgery","volume":"12","author":"Cranny","year":"2008","journal-title":"Health Technology Assessment"},{"issue":"2","key":"10.1002\/14651858.CD000244.pub2-BIB0067|cit67","first-page":"72","article-title":"Evaluation of therapeutic trials published apropos of antibiotic prophylaxis in orthopedic surgery","volume":"75","author":"Doyon","year":"1989","journal-title":"Revue de Chirurgie Orthopedique et Reparatrice de l Appareil Moteur."},{"key":"10.1002\/14651858.CD000244.pub2-BIB0068|cit68","unstructured":"Higgins JPT, Altman DG Chapter 8. Assessing risk of bias in included studies. In: Higgins JPT, Green S (editors). Cochrane Handbook of Systematic Reviews of Interventions Version 5.0.2 [updated September 2009]. The Cochrane Collaboration, 2009. Available from www.cochrane-handbook.org"},{"key":"10.1002\/14651858.CD000244.pub2-BIB0069|cit69","unstructured":"Lefebvre C Manheimer E Glanville J Chapter 6: Searching for studies. In: Higgins JPT, Green S (editors). Cochrane Handbook for Systematic Reviews of Interventions Version 5.0.2 (updated September 2009) The Cochrane Collaboration, 2009. Available from www.cochrane-handbook.org"},{"issue":"1","key":"10.1002\/14651858.CD000244.pub2-BIB0070|cit70","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1093\/jac\/49.1.25","article-title":"The 2000 Garrod lecture. Factors impacting on the problem of antibiotic resistance","volume":"49","author":"Levy","year":"2002","journal-title":"Journal of Antimicrobial Chemotherapy"},{"issue":"8","key":"10.1002\/14651858.CD000244.pub2-BIB0071|cit71","doi-asserted-by":"crossref","first-page":"657","DOI":"10.7326\/0003-4819-134-8-200104170-00011","article-title":"The CONSORT statement: revised recommendations for improving the quality of reports of parallel group randomized trials","volume":"134","author":"Moher","year":"2001","journal-title":"Annals of Internal Medicine"},{"issue":"Suppl 10","key":"10.1002\/14651858.CD000244.pub2-BIB0072|cit72","doi-asserted-by":"crossref","first-page":"842","DOI":"10.1093\/clinids\/13.Supplement_10.S842","article-title":"Antibiotic prophylaxis in orthopaedic surgery","volume":"13","author":"Norden","year":"1991","journal-title":"Reviews of Infectious Diseases"},{"issue":"Suppl 10","key":"10.1002\/14651858.CD000244.pub2-BIB0073|cit73","doi-asserted-by":"crossref","first-page":"810","DOI":"10.1093\/clinids\/13.Supplement_10.S810","article-title":"Methodological aspects of clinical studies of perioperative antibiotic prophylaxis","volume":"13","author":"Platt","year":"1991","journal-title":"Reviews of Infectious Diseases"},{"issue":"8","key":"10.1002\/14651858.CD000244.pub2-BIB0074|cit74","doi-asserted-by":"crossref","first-page":"1175","DOI":"10.1086\/605630","article-title":"Hospital and societal costs of antimicrobial-resistant infections in a Chicago teaching hospital:implications for antibiotic stewardship.","volume":"49","author":"Roberts","year":"2009","journal-title":"Clinical Infectious Diseases \u00a0"},{"issue":"4","key":"10.1002\/14651858.CD000244.pub2-BIB0075|cit75","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1097\/BOT.0b013e31816b7880","article-title":"Single- versus multiple-dose antibiotic prophylaxis in the surgical treatment of closed fractures: a meta-analysis","volume":"22","author":"Slobogean","year":"2008","journal-title":"Journal of Orthopaedic Trauma"},{"key":"10.1002\/14651858.CD000244.pub2-BIB0076|cit76","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1097\/00003086-200402000-00029","article-title":"Antibiotic prophylaxis in hip fracture surgery: a metaanalysis","volume":"(419)","author":"Southwell-Keely","year":"2004","journal-title":"Clinical Orthopaedics & Related Research"}],"container-title":["Cochrane Database of Systematic Reviews"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/onlinelibrary.wiley.com\/wol1\/doi\/10.1002\/14651858.CD000244.pub2\/fullpdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,7,21]],"date-time":"2025-07-21T06:01:46Z","timestamp":1753077706000},"score":1,"resource":{"primary":{"URL":"http:\/\/doi.wiley.com\/10.1002\/14651858.CD000244.pub2"}},"subtitle":[],"editor":[{"name":"Cochrane Bone, Joint and Muscle Trauma Group","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2010,3,17]]},"references-count":76,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2010,3]]}},"URL":"https:\/\/doi.org\/10.1002\/14651858.cd000244.pub2","relation":{},"ISSN":["1465-1858"],"issn-type":[{"value":"1465-1858","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,3,17]]}}}