{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T16:16:57Z","timestamp":1788452217744,"version":"build-2803163510"},"update-to":[{"DOI":"10.1002\/14651858.cd000553.pub2","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2020,10,22]],"date-time":"2020-10-22T00:00:00Z","timestamp":1603324800000}}],"reference-count":133,"publisher":"Wiley","issue":"10","content-domain":{"domain":["wiley.com","cochranelibrary.com"],"crossmark-restriction":true},"short-container-title":[],"DOI":"10.1002\/14651858.cd000553.pub3","type":"journal-article","created":{"date-parts":[[2020,10,22]],"date-time":"2020-10-22T09:06:43Z","timestamp":1603357603000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Portosystemic shunts versus endoscopic intervention with or without medical treatment for prevention of rebleeding in people with cirrhosis"],"prefix":"10.1002","volume":"2020","author":[{"given":"Rosa G","family":"Simonetti","sequence":"additional","affiliation":[{"name":"Cochrane Hepato-Biliary Group; Copenhagen Trial Unit, Centre for Clinical Intervention Research, Department 7812, Rigshospitalet, Copenhagen University Hospital; Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giovanni","family":"Perricone","sequence":"additional","affiliation":[{"name":"S.C. Epatologia e Gastroenterologia; Azienda Socio-Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda; Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Helen L","family":"Robbins","sequence":"additional","affiliation":[{"name":"Department of Surgery; University Hospital Coventry and Warwickshire; Coventry UK"},{"name":"University Hospitals Birmingham NHS Foundation Trust; Birmingham UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Narendra R","family":"Battula","sequence":"additional","affiliation":[{"name":"Division of Hepatobiliary and Abdominal Transplant surgery; University of Florida; Gainesville Florida USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin O","family":"Weickert","sequence":"additional","affiliation":[{"name":"The ARDEN NET Centre, ENETS Centre of Excellence; University Hospitals Coventry and Warwickshire NHS Trust; Coventry UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Sutton","sequence":"additional","affiliation":[{"name":"Institute of Translational Medicine, University of Liverpool; Liverpool UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saboor","family":"Khan","sequence":"additional","affiliation":[{"name":"Surgery; University Hosptial Coventry and Warwickshire; Coventry UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,10,22]]},"reference":[{"issue":"3","key":"10.1002\/14651858.CD000553.pub3-BIB0001|cit1","doi-asserted-by":"publisher","first-page":"832","DOI":"10.1053\/gast.1996.v110.pm8608893","article-title":"Transjugular intrahepatic portosystemic shunt versus sclerotherapy in the elective treatment of variceal hemorrhage","volume":"110","author":"Cabrera","year":"1996","journal-title":"Gastroenterology"},{"issue":"11","key":"10.1002\/14651858.CD000553.pub3-BIB0002|cit2","doi-asserted-by":"publisher","first-page":"858","DOI":"10.7326\/0003-4819-126-11-199706010-00002","article-title":"Endoscopic sclerotherapy compared with percutaneous transjugular Intrahepatic portosystemic shunt after initial sclerotherapy in patients with acute variceal haemorrhage. A randomised controlled trial","volume":"126","author":"Cello","year":"1997","journal-title":"Annals of Internal Medicine"},{"issue":"1","key":"10.1002\/14651858.CD000553.pub3-BIB0003|cit3","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1111\/apt.15797","article-title":"Randomised clinical trial: standard of care versus early-transjugular intrahepatic porto-systemic shunt (TIPSS) in patients with cirrhosis and oesophageal variceal bleeding","volume":"52","author":"Dunne","year":"2020","journal-title":"Alimentary Pharmacology & Therapeutics"},{"issue":"Suppl 2","key":"10.1002\/14651858.CD000553.pub3-BIB0004|cit4","doi-asserted-by":"crossref","first-page":"S555","DOI":"10.1016\/S0168-8278(12)61421-4","article-title":"A randomized, controlled, multicentre trial comparing endoscopic band ligation versus tips in cirrhotic patients with recurrent variceal bleeding non-responding to pharmacological therapy","volume":"56","author":"Ferlitsch","year":"2012","journal-title":"Journal of Hepatology"},{"issue":"1","key":"10.1002\/14651858.CD000553.pub3-BIB0005|cit5","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1002\/hep.510290125","article-title":"Transjugular Intrahepatic portosystemic shunt versus prevention of rebleeding after recent variceal hemorrhage","volume":"29","author":"Garc\u00eda-Villarreal","year":"1999","journal-title":"Hepatology (Baltimore, Md.)"},{"issue":"S4","key":"10.1002\/14651858.CD000553.pub3-BIB0006|cit6","first-page":"297A","article-title":"TIPS versus sclerotherapy + propranolol in the prevention of variceal rebleeding: preliminary results of a multicenter randomised trial","volume":"22","author":"Groupe d'Etude de Anastomoses Intra-Hepatiques","year":"1995","journal-title":"Hepatology (Baltimore, Md.)"},{"issue":"3","key":"10.1002\/14651858.CD000553.pub3-BIB0007|cit7","doi-asserted-by":"publisher","first-page":"338","DOI":"10.1080\/003655202317284255","article-title":"Transjugular intrahepatic portosystemic shunting is not superior to endoscopic variceal band ligation for prevention of variceal rebleeding in cirrhotic patients: a randomized, controlled trial","volume":"37","author":"G\u00fclberg","year":"2002","journal-title":"Scandinavian Journal of Gastroenterology"},{"issue":"4","key":"10.1002\/14651858.CD000553.pub3-BIB0008|cit8","doi-asserted-by":"publisher","first-page":"262","DOI":"10.7326\/0003-4819-112-4-262","article-title":"Endoscopic variceal sclerosis compared with distal splenorenal shunt to prevent recurrent variceal bleeding in cirrhosis, a prospective randomized trial","volume":"112","author":"Henderson","year":"1990","journal-title":"Annals of Internal Medicine"},{"issue":"5","key":"10.1002\/14651858.CD000553.pub3-BIB0009|cit9","doi-asserted-by":"publisher","first-page":"454","DOI":"10.1097\/00000658-198605000-00002","article-title":"Distal splenorenal shunt versus endoscopic sclerotherapy for long-term management of variceal bleeding: preliminary report of a prospective, randomised trial","volume":"203","author":"Warren","year":"1986","journal-title":"Annals of Surgery"},{"issue":"4 Suppl 1","key":"10.1002\/14651858.CD000553.pub3-BIB0010|cit10","doi-asserted-by":"crossref","first-page":"S1160","DOI":"10.1016\/S0016-5085(16)33918-X","article-title":"Cost effectiveness of covered transjugular intrahepatic portosystemic shunt (TIPS) versus endoscopic treatment for secondary prevention of gastro-oesophageal variceal rebleeding","volume":"150","author":"Harki","year":"2016","journal-title":"Gastroenterology"},{"issue":"2 Suppl","key":"10.1002\/14651858.CD000553.pub3-BIB0011|cit11","doi-asserted-by":"crossref","first-page":"S265","DOI":"10.1016\/S0168-8278(16)00303-2","article-title":"Cost effectiveness of covered transjugular intrahepatic portosystemic shunt versus endoscopic treatment for secondary prevention of gastro-oesophageal variceal bleeding","volume":"64","author":"Harki","year":"2016","journal-title":"Journal of Hepatology"},{"issue":"S1","key":"10.1002\/14651858.CD000553.pub3-BIB0012|cit12","first-page":"A84","article-title":"Early transjugular intrahepatic portosystemic shunt (TIPS) as compared to endoscopic treatment reduces rebleeding but not mortality in cirrhotic patients with a 1st or 2nd episode of variceal bleeding: a multicentre randomized controlled trial","volume":"1","author":"Holster","year":"2013","journal-title":"United European Gastroenterology Journal"},{"issue":"2","key":"10.1002\/14651858.CD000553.pub3-BIB0013|cit13","doi-asserted-by":"publisher","first-page":"581","DOI":"10.1002\/hep.28318","article-title":"Covered transjugular intrahepatic portosystemic shunt versus endoscopic therapy + \u00df-blocker for prevention of variceal rebleeding","volume":"63","author":"Holster","year":"2016","journal-title":"Hepatology (Baltimore, Md.)"},{"issue":"5","key":"10.1002\/14651858.CD000553.pub3-BIB0014|cit14","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1016\/S0039-6060(05)80248-X","article-title":"Mesocaval shunt or repeated sclerotherapy: effects on rebleeding and encephalopathy - a randomized trial","volume":"117","author":"Isaksson","year":"1995","journal-title":"Surgery"},{"issue":"4","key":"10.1002\/14651858.CD000553.pub3-BIB0015|cit15","doi-asserted-by":"crossref","first-page":"251A","DOI":"10.1016\/0270-9139(95)94727-2","article-title":"TIPSS vs variceal band ligation in the secondary prevention of variceal hemorrhage in cirrhosis: preliminary results of a randomised, controlled study","volume":"22","author":"Jalan","year":"1995","journal-title":"Hepatology (Baltimore, Md.)"},{"issue":"5","key":"10.1002\/14651858.CD000553.pub3-BIB0016|cit16","doi-asserted-by":"publisher","first-page":"1115","DOI":"10.1002\/hep.510260505","article-title":"A randomized trial comparing transjugular intrahepatic portosystemic stent-shunt with variceal band ligation in the prevention of rebleeding from esophageal varices","volume":"26","author":"Jalan","year":"1997","journal-title":"Hepatology (Baltimore, Md.)"},{"key":"10.1002\/14651858.CD000553.pub3-BIB0017|cit17","first-page":"1745","article-title":"A prospective randomised controlled comparison of chronic endoscopic variceal sclerotherapy and portalsystemic shunt for variceal hemorrhage in Child's Class A cirrhotics: a preliminary report","volume":"92","author":"Korula","year":"1987","journal-title":"Gastroenterology"},{"issue":"8","key":"10.1002\/14651858.CD000553.pub3-BIB0018|cit18","doi-asserted-by":"publisher","first-page":"679","DOI":"10.1055\/s-2007-966591","article-title":"A prospective, randomized controlled trial of transjugular intrahepatic portosystemic shunt versus cyanoacrylate injection in the prevention of gastric variceal rebleeding","volume":"39","author":"Lo","year":"2007","journal-title":"Endoscopy"},{"issue":"1","key":"10.1002\/14651858.CD000553.pub3-BIB0019|cit19","doi-asserted-by":"publisher","first-page":"286","DOI":"10.1148\/radiol.15141252","article-title":"Advanced cirrhosis combined with portal vein thrombosis: a randomized trial of TIPS versus endoscopic band ligation plus propranolol for the prevention of recurrent esophageal variceal bleeding","volume":"276","author":"Luo","year":"2015","journal-title":"Radiology"},{"key":"10.1002\/14651858.CD000553.pub3-BIB0020|cit20","doi-asserted-by":"crossref","unstructured":"Lv Y Qi X He C Wang Z Yin Z Niu J Covered TIPS versus endoscopic band ligation plus propranolol for the prevention of variceal rebleeding in cirrhotic patients with portal vein thrombosis: a randomised controlled trial Gut 2018 67 12 2156 68 28970291","DOI":"10.1136\/gutjnl-2017-314634"},{"issue":"7","key":"10.1002\/14651858.CD000553.pub3-BIB0021|cit21","doi-asserted-by":"crossref","first-page":"1162","DOI":"10.1136\/bmjopen-2013-003370","article-title":"Transjugular intrahepatic portosystemic shunt for the prevention of variceal rebleeding in cirrhotic patients with portal vein thrombosis: study protocol for a randomised controlled trial","volume":"3","author":"Qi","year":"2013","journal-title":"BMJ Open"},{"issue":"4","key":"10.1002\/14651858.CD000553.pub3-BIB0022|cit22","first-page":"A107","article-title":"Transjugular intrahepatic portosystemic shunt (TIPS) vs endoscopic sclerotherapy (ES) in preventing variceal rebleeding preliminary results of a randomized controlled trial","volume":"20","author":"Merli","year":"1994","journal-title":"Hepatology (Baltimore, Md.)"},{"issue":"1","key":"10.1002\/14651858.CD000553.pub3-BIB0023|cit23","doi-asserted-by":"publisher","first-page":"48","DOI":"10.1002\/hep.510270109","article-title":"Transjugular intrahepatic portosystemic shunt versus endoscopic sclerotherapy for the prevention of variceal bleeding in cirrhosis: a randomized multicenter trial. Gruppo Italiano Studio TIPS (G.I.S.T.)","volume":"27","author":"Merli","year":"1998","journal-title":"Hepatology (Baltimore, Md.)"},{"issue":"5","key":"10.1002\/14651858.CD000553.pub3-BIB0024|cit24","first-page":"585","article-title":"Transjugular intrahepatic portosystemic shunt (TIPS): indications and results after 22 months of experience","volume":"87","author":"Rossi","year":"1994","journal-title":"Radiologica Medica"},{"issue":"3","key":"10.1002\/14651858.CD000553.pub3-BIB0025|cit25","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/S1386-6346(01)00104-8","article-title":"A randomized clinical trial comparing transjugular intrahepatic portosystemic shunt with endoscopic sclerotherapy in the long-term management of patients with cirrhosis after recent variceal hemorrhage","volume":"21","author":"Narahara","year":"2001","journal-title":"Hepatology Research"},{"issue":"4","key":"10.1002\/14651858.CD000553.pub3-BIB0026|cit26","doi-asserted-by":"publisher","first-page":"1078","DOI":"10.1016\/0016-5085(91)90285-s","article-title":"Portacaval shunt versus endoscopic sclerotherapy in the elective treatment of variceal hemorrhage","volume":"100","author":"Planas","year":"1991","journal-title":"Gastroenterology"},{"issue":"4","key":"10.1002\/14651858.CD000553.pub3-BIB0027|cit27","first-page":"137A","article-title":"TIPS versus endoscopic variceal ligation in the prevention of variceal rebleeding in cirrhotic patients: a comparative randomized clinical trial (interm analysis)","volume":"26","author":"Pomier-Layrargues","year":"1997","journal-title":"Hepatology (Baltimore, Md.)"},{"issue":"3","key":"10.1002\/14651858.CD000553.pub3-BIB0028|cit28","doi-asserted-by":"publisher","first-page":"390","DOI":"10.1136\/gut.48.3.390","article-title":"Transjugular intrahepatic portosystemic shunt (TIPS) versus endoscopic variceal ligation in the prevention of variceal rebleeding in patients with cirrhosis: a randomised trial","volume":"48","author":"Pomier-Layrargues","year":"2001","journal-title":"Gut"},{"issue":"3","key":"10.1002\/14651858.CD000553.pub3-BIB0029|cit29","doi-asserted-by":"publisher","first-page":"261","DOI":"10.1097\/00000658-198709000-00004","article-title":"Shunt surgery versus endoscopic sclerotherapy for long-term treatment of variceal bleeding. Early results of a randomized trial","volume":"206","author":"Rikkers","year":"1987","journal-title":"Annals of Surgery"},{"issue":"1","key":"10.1002\/14651858.CD000553.pub3-BIB0030|cit30","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1016\/s0002-9610(05)80400-3","article-title":"Shunt surgery versus endoscopic sclerotherapy for variceal hemorrhage: late results of a randomized trial","volume":"165","author":"Rikkers","year":"1993","journal-title":"American Journal of Surgery"},{"issue":"9058","key":"10.1002\/14651858.CD000553.pub3-BIB0031|cit31","doi-asserted-by":"publisher","first-page":"1043","DOI":"10.1016\/s0140-6736(96)08189-5","article-title":"Randomised trial of transjugular intrahepatic portosystemic shunt versus endoscopy plus propranolol for prevention of variceal rebleeding","volume":"349","author":"Rossle","year":"1997","journal-title":"Lancet"},{"issue":"39","key":"10.1002\/14651858.CD000553.pub3-BIB0032|cit32","doi-asserted-by":"publisher","first-page":"6331","DOI":"10.3748\/wjg.v12.i39.6331","article-title":"Natural history of a randomized trial comparing distal spleno-renal shunt with endoscopic sclerotherapy in the prevention of variceal rebleeding: a lesson from the past","volume":"12","author":"Santambrogio","year":"2006","journal-title":"World Journal of Gastroenterology"},{"issue":"2","key":"10.1002\/14651858.CD000553.pub3-BIB0033|cit33","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1097\/00000658-199002000-00010","article-title":"Distal splenorenal shunt versus endoscopic sclerotherapy in the prevention of variceal rebleeding. First stage of a randomized, controlled trial","volume":"211","author":"Spina","year":"1990","journal-title":"Annals of Surgery"},{"issue":"11","key":"10.1002\/14651858.CD000553.pub3-BIB0034|cit34","doi-asserted-by":"publisher","first-page":"849","DOI":"10.7326\/0003-4819-126-11-199706010-00001","article-title":"Transjugular intrahepatic portosystemic shunts compared with endoscopic sclerotherapy for the prevention of recurrent variceal hemorrhage. A randomized, controlled trial","volume":"126","author":"Sanyal","year":"1997","journal-title":"Annals of Internal Medicine"},{"issue":"1","key":"10.1002\/14651858.CD000553.pub3-BIB0035|cit35","doi-asserted-by":"publisher","first-page":"121","DOI":"10.1016\/s0168-8278(97)80290-5","article-title":"MRI findings in chronic hepatic encephalopathy depend on portosystemic shunt: results of a controlled prospective clinical investigation","volume":"27","author":"Krieger","year":"1997","journal-title":"Journal of Hepatology"},{"issue":"5","key":"10.1002\/14651858.CD000553.pub3-BIB0036|cit36","doi-asserted-by":"publisher","first-page":"1623","DOI":"10.1053\/gast.1997.v113.pm9352865","article-title":"Transjugular intrahepatic portosystemic stent shunt versus sclerotherapy plus propranolol for variceal rebleeding","volume":"113","author":"Sauer","year":"1997","journal-title":"Gastroenterology"},{"issue":"4","key":"10.1002\/14651858.CD000553.pub3-BIB0037|cit37","first-page":"A1334","article-title":"Transjugular intrahepatic portosystemic stent shunt (TIPS) vs. endoscopic banding in the prevention of variceal rebleeding: final results of a randomized study","volume":"114","author":"Sauer","year":"1998","journal-title":"Gastroenterology"},{"issue":"4 Pt 2","key":"10.1002\/14651858.CD000553.pub3-BIB0038|cit38","doi-asserted-by":"crossref","first-page":"A1485","DOI":"10.1016\/S0016-5085(00)81844-2","article-title":"Transjugular intrahepatic portosystemic stent shunt (TIPS) vs. endoscopic banding in the prevention of variceal rebleeding: a long-term randomized trial","volume":"118","author":"Sauer","year":"2000","journal-title":"Gastroenterology"},{"issue":"9","key":"10.1002\/14651858.CD000553.pub3-BIB0039|cit39","doi-asserted-by":"publisher","first-page":"690","DOI":"10.1055\/s-2002-33565","article-title":"Endoscopic variceal ligation plus propranolol versus transjugular intrahepatic portosystemic stent shunt: a long-term randomized trial","volume":"34","author":"Sauer","year":"2002","journal-title":"Endoscopy"},{"issue":"4","key":"10.1002\/14651858.CD000553.pub3-BIB0040|cit40","first-page":"A1374","article-title":"Transjugular intrahepatic portosystemic stent shunt (TIPS) vs. endoscopic banding in the prevention of variceal rebleeding: interim analysis of a randomized study","volume":"112","author":"Sauer","year":"1997","journal-title":"Gastroenterology"},{"issue":"3","key":"10.1002\/14651858.CD000553.pub3-BIB0041|cit41","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1002\/hep.1840070303","article-title":"Sclerotherapy vs. distal splenorenal shunt in the elective treatment of variceal hemorrhage: a randomized controlled trial","volume":"7","author":"Ter\u00e9s","year":"1987","journal-title":"Hepatology (Baltimore, Md.)"},{"issue":"3","key":"10.1002\/14651858.CD000553.pub3-BIB0042|cit42","first-page":"195","article-title":"Prevention of recurrent esophageal bleeding and survival in patients with alcoholic cirrhosis: a randomized study","volume":"15","author":"Urbistondo","year":"1996","journal-title":"Puerto Rico Health Sciences Journal"},{"issue":"3","key":"10.1002\/14651858.CD000553.pub3-BIB0043|cit43","first-page":"333","article-title":"Endoscopic sclerotherapy versus esophageal transection of Child's class C patients with variceal hemorrhage. Comparison with results of portacaval shunt: preliminary report","volume":"91","author":"Cello","year":"1982","journal-title":"Surgery"},{"issue":"25","key":"10.1002\/14651858.CD000553.pub3-BIB0044|cit44","doi-asserted-by":"publisher","first-page":"1589","DOI":"10.1056\/NEJM198412203112501","article-title":"Endoscopic sclerothearpy versus portacaval shunt in patients with severe cirrhosis and variceal hemorrhage","volume":"311","author":"Cello","year":"1984","journal-title":"New England Journal of Medicine"},{"issue":"1","key":"10.1002\/14651858.CD000553.pub3-BIB0045|cit45","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1056\/NEJM198701013160103","article-title":"Endoscopic sclerotherapy versus portacaval shunt in patients with severe cirrhosis and acute variceal hemorrhage. Long-term follow-up","volume":"316","author":"Cello J","year":"1987","journal-title":"New England Journal of Medicine"},{"issue":"2","key":"10.1002\/14651858.CD000553.pub3-BIB0046|cit46","doi-asserted-by":"publisher","first-page":"385","DOI":"10.1053\/jhep.2002.30418","article-title":"TIPS versus drug therapy in preventing variceal rebleeding in advanced cirrhosis: a randomized controlled trial","volume":"35","author":"Escorsell","year":"2002","journal-title":"Hepatology (Baltimore, Md.)"},{"issue":"25","key":"10.1002\/14651858.CD000553.pub3-BIB0047|cit47","doi-asserted-by":"publisher","first-page":"2370","DOI":"10.1056\/NEJMoa0910102.","article-title":"Early use of TIPS in patients with cirrhosis and variceal bleeding","volume":"362","author":"Garc\u00eda-Pag\u00e1n","year":"2010","journal-title":"New England Journal of Medicine"},{"issue":"1","key":"10.1002\/14651858.CD000553.pub3-BIB0048|cit48","doi-asserted-by":"publisher","first-page":"63","DOI":"10.1002\/hep.1840150113","article-title":"Sclerotherapy vs. esophageal transection vs. distal splenorenal shunt for the clinical management of esophageal varices in patients with child class A and B liver function: a prospective randomized trial","volume":"15","author":"Kitano","year":"1992","journal-title":"Hepatology (Baltimore, Md.)"},{"issue":"10","key":"10.1002\/14651858.CD000553.pub3-BIB0049|cit49","first-page":"19709","article-title":"Hepatic venous pressure gradient is a useful predictor in guiding treatment on prevention of variceal rebleeding in cirrhosis","volume":"8","author":"Li","year":"2015","journal-title":"International Journal of Clinical and Experimental Medicine"},{"issue":"4","key":"10.1002\/14651858.CD000553.pub3-BIB0050|cit50","doi-asserted-by":"publisher","first-page":"1074","DOI":"10.1002\/hep.510290411","article-title":"Cost analysis for the prevention of variceal rebleeding: a comparison between transjugular intrahepatic portosystemic shunt and endoscopic sclerotherapy in a selected group of Italian cirrhotic patients","volume":"29","author":"Meddi","year":"1999","journal-title":"Hepatology (Baltimore, Md.)"},{"issue":"4 Pt 1","key":"10.1002\/14651858.CD000553.pub3-BIB0051|cit51","doi-asserted-by":"publisher","first-page":"863","DOI":"10.1002\/hep.1840200414","article-title":"Prospective randomized trial of emergency portacaval shunt and emergency medical therapy in unselected cirrhotic patients with bleeding varices","volume":"20","author":"Orloff","year":"1994","journal-title":"Hepatology (Baltimore, Md.)"},{"issue":"4","key":"10.1002\/14651858.CD000553.pub3-BIB0052|cit52","doi-asserted-by":"publisher","first-page":"598","DOI":"10.1097\/SLA.0b013e3181b73126","article-title":"Portal-systemic encephalopathy in a randomized controlled trial of endoscopic sclerotherapy versus emergency portacaval shunt treatment of acutely bleeding esophageal varices in cirrhosis","volume":"250","author":"Orloff","year":"2009","journal-title":"Annals of Surgery"},{"issue":"1","key":"10.1002\/14651858.CD000553.pub3-BIB0053|cit53","doi-asserted-by":"publisher","first-page":"38","DOI":"10.1007\/s11605-010-1332-6","article-title":"Direct costs of care in a randomized controlled trial of endoscopic sclerotherapy versus emergency portacaval shunt for bleeding esophageal varices in cirrhosis - Part 4","volume":"15","author":"Orloff","year":"2011","journal-title":"Journal of Gastrointestinal Surgery"},{"issue":"11","key":"10.1002\/14651858.CD000553.pub3-BIB0054|cit54","doi-asserted-by":"publisher","first-page":"1782","DOI":"10.1007\/s11605-010-1279-7","article-title":"Emergency portacaval shunt versus rescue portacaval shunt in a randomized controlled trial of emergency treatment of acutely bleeding esophageal varices in cirrhosis - Part 3","volume":"14","author":"Orloff","year":"2010","journal-title":"Journal of Gastrointestinal Surgery"},{"issue":"2","key":"10.1002\/14651858.CD000553.pub3-BIB0055|cit55","doi-asserted-by":"publisher","first-page":"155","DOI":"10.1001\/jamasurg.2013.4045","article-title":"Fifty-three years' experience with randomized clinical trials of emergency portacaval shunt for bleeding esophageal varices in cirrhosis: 1958 - 2011","volume":"149","author":"Orloff","year":"2014","journal-title":"Journal of the American Medical Association Surgery"},{"issue":"6","key":"10.1002\/14651858.CD000553.pub3-BIB0056|cit56","doi-asserted-by":"crossref","first-page":"1028","DOI":"10.1016\/j.surg.2014.12.003","article-title":"Randomized trials of endoscopic therapy and transjugular intrahepatic portosystemic shunt versus portacaval shunt for emergency and elective treatment of bleeding gastric varices in cirrhosis","volume":"157","author":"Orloff","year":"2015","journal-title":"Surgery"},{"issue":"1","key":"10.1002\/14651858.CD000553.pub3-BIB0057|cit57","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1016\/j.jamcollsurg.2009.02.059","article-title":"Randomized trial of emergency endoscopic sclerotherapy versus emergency portacaval shunt for acutely bleeding esophageal varices in cirrhosis","volume":"209","author":"Orloff","year":"2009","journal-title":"Journal of the American College of Surgeons"},{"key":"10.1002\/14651858.CD000553.pub3-BIB0058|cit58","first-page":"397","article-title":"Surgical measures in recurrent hemorrhage from esophageal and gastric varices after sclerotherapy - a prospective study","volume":"Suppl II","author":"Paquet","year":"1990","journal-title":"Langenbecks Archiv fu\u0308r Chirurgie. Supplement II, Verhandlungen der Deutschen Gesellschaft fu\u0308r Chirurgie"},{"issue":"5","key":"10.1002\/14651858.CD000553.pub3-BIB0059|cit59","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1016\/S0016-5085(19)32736-2","article-title":"A controlled study of the therapeutic portacaval shunt","volume":"6","author":"Resnick","year":"1974","journal-title":"Gastroenterology"},{"issue":"5 Pt 1","key":"10.1002\/14651858.CD000553.pub3-BIB0060|cit60","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.1016\/0016-5085(81)90073-1","article-title":"Results of a 12-year randomized trial of portacaval shunt in patients with alcoholic liver disease and bleeding varices","volume":"80","author":"Reynolds","year":"1981","journal-title":"Gastroenterology"},{"issue":"1 Pt 1","key":"10.1002\/14651858.CD000553.pub3-BIB0061|cit61","doi-asserted-by":"publisher","first-page":"46","DOI":"10.1016\/0270-9139(94)90133-3","article-title":"Portosystemic encephalopathy after transjugular intrahepatic portosystemic shunt: results of a prospective controlled study","volume":"20","author":"Sanyal","year":"1994","journal-title":"Hepatology (Baltimore, Md.)"},{"issue":"5","key":"10.1002\/14651858.CD000553.pub3-BIB0062|cit62","first-page":"277","article-title":"Hepatic encephalopathy after transjugular intrahepatic portosystemic stent shunt (TIPS)","volume":"33","author":"Sauer","year":"1995","journal-title":"Zeitschrift f\u00fcr Gastroenterologie"},{"issue":"3","key":"10.1002\/14651858.CD000553.pub3-BIB0063|cit63","doi-asserted-by":"crossref","first-page":"660","DOI":"10.1053\/j.gastro.2015.05.011","article-title":"Prevention of rebleeding from esophageal varices in patients with cirrhosis receiving small-diameter stents versus hemodynamically controlled medical therapy","volume":"149","author":"Sauerbruch","year":"2015","journal-title":"Gastroenterology"},{"issue":"2","key":"10.1002\/14651858.CD000553.pub3-BIB0064|cit64","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/S0168-8278(87)80075-2","article-title":"Randomized trial of portacaval shunt, stapling transection and endoscopic sclerotherapy in uncontrolled variceal bleeding","volume":"4","author":"Ter\u00e9s","year":"1987","journal-title":"Journal of Hepatology"},{"issue":"Suppl 1","key":"10.1002\/14651858.CD000553.pub3-BIB0065|cit65","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1016\/S0168-8278(01)81114-4","article-title":"Randomized controlled trial of transjugular intra-hepatic portosystemic stent-shunt (TIPSS) versus TIPSS and variceal band ligation (VBL) in the prevention of variceal re-bleeding","volume":"34","author":"Tripathi","year":"2001","journal-title":"Journal of Hepatology"},{"issue":"6","key":"10.1002\/14651858.CD000553.pub3-BIB0066|cit66","doi-asserted-by":"publisher","first-page":"1813","DOI":"10.1007\/s00261-014-0320-9","article-title":"Clinical outcome comparison between TIPS and EBL in patients with cirrhosis and portal vein thrombosis","volume":"40","author":"Wang","year":"2015","journal-title":"Abdominal Imaging"},{"issue":"8","key":"10.1002\/14651858.CD000553.pub3-BIB0067|cit67","doi-asserted-by":"publisher","first-page":"587","DOI":"10.1016\/S2468-1253(19)30090-1","article-title":"Early TIPS with covered stents versus standard treatment for acute variceal bleeding in patients with advanced cirrhosis: a randomised controlled trial","volume":"4","author":"Lv","year":"2019","journal-title":"The Lancet Gastroenterology and Hepatology"},{"key":"10.1002\/14651858.CD000553.pub3-BIB0068|cit68","unstructured":"8mm-TIPS versus endoscopic variceal ligation (EVL) plus propranolol for prevention of variceal rebleeding clinicaltrials.gov\/ct2\/show\/study\/NCT02477384"},{"key":"10.1002\/14651858.CD000553.pub3-BIB0069|cit69","unstructured":"8mm-TIPS versus endoscopic variceal ligation (EVL) plus propranolol for prevention of variceal rebleeding in patients with child A cirrhosis clinicaltrials.gov\/ct2\/show\/study\/NCT03094234"},{"issue":"11","key":"10.1002\/14651858.CD000553.pub3-BIB0070|cit70","doi-asserted-by":"crossref","first-page":"1166","DOI":"10.3748\/wjg.v18.i11.1166","article-title":"Treatment of portal hypertension","volume":"18","author":"Bari","year":"2012","journal-title":"World Journal of Gastroenterology"},{"issue":"2","key":"10.1002\/14651858.CD000553.pub3-BIB0071|cit71","doi-asserted-by":"publisher","first-page":"312","DOI":"10.1016\/s0168-8278(97)80047-5","article-title":"Propranolol and sclerotherapy in the prevention of gastrointestinal rebleeding in patients with cirrhosis: a meta-analysis","volume":"26","author":"Bernard","year":"1997","journal-title":"Journal of Hepatology"},{"issue":"8","key":"10.1002\/14651858.CD000553.pub3-BIB0072|cit72","doi-asserted-by":"publisher","first-page":"763","DOI":"10.1016\/j.jclinepi.2007.10.007","article-title":"Trial sequential analysis reveals insufficient information size and potentially false positive results in many meta-analyses","volume":"61","author":"Brok","year":"2008","journal-title":"Journal of Clinical Epidemiology"},{"issue":"1","key":"10.1002\/14651858.CD000553.pub3-BIB0073|cit73","doi-asserted-by":"publisher","first-page":"287","DOI":"10.1093\/ije\/dyn188","article-title":"Apparently conclusive meta-analyses may be inconclusive - trial sequential analysis adjustment of random error risk due to repetitive testing of accumulating data in apparently conclusive neonatal meta-analyses","volume":"38","author":"Brok","year":"2009","journal-title":"International Journal of Epidemiology"},{"key":"10.1002\/14651858.CD000553.pub3-BIB0074|cit74","first-page":"485","article-title":"Transjugular intrahepatic portosystemic shunt as a form of treatment for portal hypertension: indications and contraindications","volume":"42","author":"Lake","year":"1997","journal-title":"Advances in Internal Medicine"},{"issue":"6","key":"10.1002\/14651858.CD000553.pub3-BIB0075|cit75","doi-asserted-by":"publisher","first-page":"742","DOI":"10.1111\/j.1478-3231.2007.01522.x","article-title":"Patency of stents covered with polytetrafluoroethylene in patients treated by transjugular intrahepatic portosystemic shunts: long-term results of a randomized multicentre study","volume":"27","author":"Pagan","year":"2007","journal-title":"Liver International"},{"issue":"3","key":"10.1002\/14651858.CD000553.pub3-BIB0076|cit76","doi-asserted-by":"publisher","first-page":"249","DOI":"10.1080\/003655202317284138","article-title":"Transjugular Intrahepatic portosystemic shunt versus endoscopic therapy: randomized trials for secondary prophylaxis of variceal bleeding: an updated meta-analysis","volume":"37","author":"Burroughs","year":"2002","journal-title":"Scandinavian Journal of Gastroenterology"},{"issue":"3","key":"10.1002\/14651858.CD000553.pub3-BIB0077|cit77","doi-asserted-by":"publisher","first-page":"652","DOI":"10.1002\/hep.20339","article-title":"Improved survival after variceal bleeding in patients with cirrhosis over the past two decades","volume":"40","author":"Carbonell","year":"2004","journal-title":"Hepatology (Baltimore, Md.)"},{"issue":"6","key":"10.1002\/14651858.CD000553.pub3-BIB0078|cit78","doi-asserted-by":"crossref","first-page":"1296","DOI":"10.1016\/S0016-5085(98)70436-6","article-title":"Clinical events after transjugular intrahepatic portosystemic shunt: correlation with hemodynamic findings","volume":"114","author":"Casado","year":"1998","journal-title":"Gastroenterology"},{"issue":"1","key":"10.1002\/14651858.CD000553.pub3-BIB0079|cit79","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1186\/s13643-018-0770-1","article-title":"Assessing imprecision in Cochrane systematic reviews: a comparison of GRADE and Trial Sequential Analysis","volume":"7","author":"Castellini","year":"2018","journal-title":"Systematic Reviews"},{"issue":"6","key":"10.1002\/14651858.CD000553.pub3-BIB0080|cit80","first-page":"527","article-title":"Surgical management of portal hypertension","volume":"162","author":"Collins","year":"1995","journal-title":"Western Journal of Medicine"},{"issue":"7","key":"10.1002\/14651858.CD000553.pub3-BIB0081|cit81","doi-asserted-by":"publisher","first-page":"312","DOI":"10.4253\/wjge.v4.i7.312","article-title":"Endoscopic management of esophageal varices","volume":"4","author":"Cordon","year":"2012","journal-title":"World Journal of Gastrointestinal Endoscopy"},{"issue":"1","key":"10.1002\/14651858.CD000553.pub3-BIB0082|cit82","doi-asserted-by":"publisher","first-page":"332","DOI":"10.1002\/hep.1840220145","article-title":"The treatment of portal hypertension: a meta-analytic review","volume":"22","author":"D'Amico","year":"1995","journal-title":"Hepatology (Baltimore, Md.)"},{"key":"10.1002\/14651858.CD000553.pub3-BIB0083|cit83","doi-asserted-by":"crossref","unstructured":"D'Amico G Esophageal varices: from appearance to rupture; natural history and prognostic indicators Groszmann RJ, Bosch J (Editors). Portal Hypertension in the 21st Century King's College London, UK Springer, Kluwer Academic Publishers 2004","DOI":"10.1007\/978-94-007-1042-9_17"},{"issue":"8","key":"10.1002\/14651858.CD000553.pub3-BIB0084|cit84","doi-asserted-by":"publisher","first-page":"2534","DOI":"10.3748\/wjg.v21.i8.2534","article-title":"Endoscopic variceal ligation compared with endoscopic injection sclerotherapy for treatment of esophageal variceal hemorrhage: a meta-analysis","volume":"21","author":"Dai","year":"2015","journal-title":"World Journal of Gastroenterology"},{"issue":"4","key":"10.1002\/14651858.CD000553.pub3-BIB0085|cit85","doi-asserted-by":"publisher","first-page":"762","DOI":"10.1016\/j.jhep.2010.06.004","article-title":"Revising consensus in portal hypertension: report of the Baverno V Consensus Workshop on Methodology of Diagnosis and Therapy in Portal Hypertension","volume":"53","author":"Franchis","year":"2010","journal-title":"Journal of Hepatology"},{"issue":"3","key":"10.1002\/14651858.CD000553.pub3-BIB0086|cit86","doi-asserted-by":"publisher","first-page":"743","DOI":"10.1016\/j.jhep.2015.05.022","article-title":"Expanding consensus in portal hypertension: Report of the Baveno VI Consensus Workshop: Stratifying risk and individualizing care for portal hypertension","volume":"63","author":"Franchis","year":"2015","journal-title":"Journal of Hepatology"},{"issue":"2","key":"10.1002\/14651858.CD000553.pub3-BIB0087|cit87","doi-asserted-by":"publisher","first-page":"406","DOI":"10.1016\/j.jhep.2018.03.024","article-title":"EASL clinical practice guidelines for the management of patients with decompensated cirrhosis","volume":"69","author":"European Association for the Study of the Liver","year":"2018","journal-title":"Journal of Hepatology"},{"issue":"7121","key":"10.1002\/14651858.CD000553.pub3-BIB0088|cit88","doi-asserted-by":"publisher","first-page":"1533","DOI":"10.1136\/bmj.315.7121.1533","article-title":"Meta-analysis: principles and procedure","volume":"315","author":"Egger","year":"1997","journal-title":"BMJ (Clinical Research Ed.)"},{"issue":"3","key":"10.1002\/14651858.CD000553.pub3-BIB0089|cit89","doi-asserted-by":"publisher","first-page":"922","DOI":"10.1002\/hep.21907","article-title":"Prevention and management of gastroesophageal varices and variceal hemorrhage in cirrhosis","volume":"46","author":"Garcia-Tsao","year":"2007","journal-title":"Hepatology (Baltimore, Md.)"},{"issue":"1","key":"10.1002\/14651858.CD000553.pub3-BIB0090|cit90","doi-asserted-by":"publisher","first-page":"310","DOI":"10.1002\/hep.28906","article-title":"Portal hypertensive bleeding in cirrhosis: risk stratification, diagnosis, and management: 2016 practice guidance by the American Association for the Study of Liver Diseases","volume":"65","author":"Garcia-Tsao","year":"2017","journal-title":"Hepatology (Baltimore, Md.)"},{"key":"10.1002\/14651858.CD000553.pub3-BIB0091|cit91","doi-asserted-by":"publisher","first-page":"50","DOI":"10.1016\/j.jclinepi.2018.10.009","article-title":"Increased risks for random errors are common in outcomes graded as high certainty of evidence","volume":"106","author":"Gartlehner","year":"2019","journal-title":"Journal of Clinical Epidemiology"},{"issue":"7","key":"10.1002\/14651858.CD000553.pub3-BIB0092|cit92","first-page":"1081","article-title":"Diagnosis and treatment of gastrointestinal bleeding secondary to portal hypertension","volume":"92","author":"Grace","year":"1997","journal-title":"American Journal of Gastroenterology"},{"key":"10.1002\/14651858.CD000553.pub3-BIB0093|cit93","unstructured":"GRADEpro GDT McMaster University (developed by Evidence Prime) 2015"},{"issue":"4","key":"10.1002\/14651858.CD000553.pub3-BIB0094|cit94","doi-asserted-by":"crossref","first-page":"800","DOI":"10.1016\/0016-5085(81)90144-X","article-title":"The course of patients after variceal haemorrhage","volume":"80","author":"Graham","year":"1981","journal-title":"Gastroenterology"},{"issue":"2","key":"10.1002\/14651858.CD000553.pub3-BIB0095|cit95","doi-asserted-by":"publisher","first-page":"347","DOI":"10.1016\/j.cld.2014.01.001","article-title":"Management of acute variceal bleeding","volume":"18","author":"Herrera","year":"2014","journal-title":"Clinics in Liver Disease"},{"key":"10.1002\/14651858.CD000553.pub3-BIB0096|cit96","unstructured":"Higgins JPT Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 (updated March 2011). The Cochrane Collaboration, 2011 Available from handbook.cochrane.org"},{"key":"10.1002\/14651858.CD000553.pub3-BIB0097|cit97","doi-asserted-by":"crossref","unstructured":"Higgins JPT Thomas J Chandler J Cumpston M Li T Page MJ Cochrane Handbook for Systematic Reviews of Interventions version 6.0 (updated August 2019). Cochrane, 2019 Available from www.training.cochrane.org\/handbook","DOI":"10.1002\/9781119536604"},{"key":"10.1002\/14651858.CD000553.pub3-BIB0098|cit98","doi-asserted-by":"publisher","first-page":"120","DOI":"10.1186\/1471-2288-14-120","article-title":"Thresholds for statistical and clinical significance in systematic reviews with meta-analytic methods","volume":"14","author":"Jakobsen","year":"2014","journal-title":"BMC Medical Research Methodology"},{"issue":"2","key":"10.1002\/14651858.CD000553.pub3-BIB0099|cit99","doi-asserted-by":"publisher","first-page":"413","DOI":"10.1148\/radiology.187.2.8475283","article-title":"Creation of transjugular intrahepatic portosystemic shunts with the wall stent endoprosthesis: results in 100 patients","volume":"187","author":"LaBerge","year":"1993","journal-title":"Radiology"},{"issue":"4","key":"10.1002\/14651858.CD000553.pub3-BIB0100|cit100","doi-asserted-by":"publisher","first-page":"280","DOI":"10.7326\/0003-4819-123-4-199508150-00007","article-title":"Endoscopic ligation compared with sclerotherapy for treatment of esophageal variceal bleeding. A meta-analysis","volume":"123","author":"Laine","year":"1995","journal-title":"Annals of Internal Medicine"},{"issue":"2","key":"10.1002\/14651858.CD000553.pub3-BIB0101|cit101","doi-asserted-by":"publisher","first-page":"411","DOI":"10.1148\/radiology.212.2.r99au46411","article-title":"TIPS for prevention of recurrent bleeding in patients with cirrhosis: meta-analysis of randomized clinical trials","volume":"212","author":"Luca","year":"1999","journal-title":"Radiology"},{"key":"10.1002\/14651858.CD000553.pub3-BIB0102|cit102","first-page":"2085","volume-title":"Oxford Textbook of Medicine","author":"McIntyre","year":"1996"},{"issue":"3","key":"10.1002\/14651858.CD000553.pub3-BIB0103|cit103","doi-asserted-by":"publisher","first-page":"612","DOI":"10.1002\/hep.510300316","article-title":"Transjugular intrahepatic portosystemic shunt compared with endoscopic treatment for prevention of variceal rebleeding: a meta-analysis","volume":"30","author":"Papatheodoridis","year":"1999","journal-title":"Hepatology (Baltimore, Md.)"},{"issue":"24","key":"10.1002\/14651858.CD000553.pub3-BIB0104|cit104","doi-asserted-by":"publisher","first-page":"2815","DOI":"10.1002\/(sici)1097-0258(19981230)17:24<2815::aid-sim110>3.0.co;2-8","article-title":"Extracting summary statistics to perform meta-analyses of the published literature for survival endpoints","volume":"17","author":"Parmar","year":"1998","journal-title":"Statistics in Medicine"},{"issue":"6","key":"10.1002\/14651858.CD000553.pub3-BIB0105|cit105","doi-asserted-by":"publisher","first-page":"823","DOI":"10.1111\/liv.12452","article-title":"Drugs plus ligation to prevent rebleeding in cirrhosis: an updated systematic review","volume":"34","author":"Puente","year":"2014","journal-title":"Liver International"},{"issue":"8","key":"10.1002\/14651858.CD000553.pub3-BIB0106|cit106","doi-asserted-by":"crossref","first-page":"646","DOI":"10.1002\/bjs.1800600817","article-title":"Transection of the oesophagus for bleeding oesophageal varices","volume":"60","author":"Pugh","year":"1973","journal-title":"British Journal of Surgery"},{"key":"10.1002\/14651858.CD000553.pub3-BIB0107|cit107","unstructured":"Review Manager (RevMan) The Nordic Cochrane Centre, The Cochrane Collaboration 2014"},{"issue":"4","key":"10.1002\/14651858.CD000553.pub3-BIB0108|cit108","doi-asserted-by":"publisher","first-page":"445","DOI":"10.1016\/j.jamcollsurg.2011.12.042","article-title":"Prosthetic H-graft portacaval shunts vs transjugular intrahepatic portosystemic stent shunts: 18-year follow-up of a randomized trial","volume":"214","author":"Rosemurgy","year":"2012","journal-title":"Journal of the American College of Surgeons"},{"issue":"4","key":"10.1002\/14651858.CD000553.pub3-BIB0109|cit109","doi-asserted-by":"publisher","first-page":"591","DOI":"10.1017\/s0266462303000552","article-title":"Literature searching for randomized controlled trials used in Cochrane reviews: rapid versus exhaustive searches","volume":"19","author":"Royle","year":"2003","journal-title":"International Journal of Technology Assessment in Health Care"},{"issue":"1","key":"10.1002\/14651858.CD000553.pub3-BIB0110|cit110","first-page":"A1334","article-title":"Tranjugular intrahepatic portosystemic stent shunt (TIPS) vs. endoscopic banding in the prevention of variceal rebleeding: final results of a randomized study","volume":"114","author":"Sauer","year":"1998","journal-title":"Gastroenterology"},{"issue":"5","key":"10.1002\/14651858.CD000553.pub3-BIB0111|cit111","doi-asserted-by":"crossref","first-page":"1113","DOI":"10.1093\/aje\/kwx344","article-title":"Association between risk-of-bias assessments and results of randomized trials in Cochrane Reviews: The ROBES Meta-Epidemiologic Study","volume":"187","author":"Savovi\u0107","year":"2018","journal-title":"American Journal of Epidemiology"},{"issue":"8","key":"10.1002\/14651858.CD000553.pub3-BIB0112|cit112","doi-asserted-by":"publisher","first-page":"844","DOI":"10.1111\/eci.12115","article-title":"Secondary prophylaxis of variceal bleeding for cirrhotic patients: a multiple-treatments meta-analysis","volume":"43","author":"Shi","year":"2013","journal-title":"European Journal of Clinical Investigation"},{"issue":"24","key":"10.1002\/14651858.CD000553.pub3-BIB0113|cit113","first-page":"1","article-title":"Quantifying the risk of error when interpreting funnel plots","volume":"4","author":"Simmonds","year":"2015","journal-title":"Systematic Reviews"},{"issue":"3","key":"10.1002\/14651858.CD000553.pub3-BIB0114|cit114","doi-asserted-by":"publisher","first-page":"338","DOI":"10.1016\/s0168-8278(05)80666-x","article-title":"Distal spleno-renal shunt versus endoscopic sclerotherapy in the prevention of variceal rebleeding. A meta-analysis of 4 randomized clinical trials","volume":"16","author":"Spina","year":"1992","journal-title":"Journal of Hepatology"},{"issue":"8363","key":"10.1002\/14651858.CD000553.pub3-BIB0115|cit115","doi-asserted-by":"publisher","first-page":"1328","DOI":"10.1016\/s0140-6736(83)91090-5","article-title":"Failure of repeated injection sclerotherapy to improve long-term survival after oesophageal variceal bleeding. A five-year prospective controlled clinical trial","volume":"2","author":"Terblanche","year":"1983","journal-title":"Lancet"},{"issue":"10","key":"10.1002\/14651858.CD000553.pub3-BIB0116|cit116","doi-asserted-by":"publisher","first-page":"1155\u201365","DOI":"10.1111\/j.1365-2036.2012.05074.x","article-title":"Meta-analysis: banding ligation and medical interventions for the prevention of rebleeding from oesophageal varices","volume":"35","author":"Thiele","year":"2012","journal-title":"Alimentary Pharmacology & Therapeutics"},{"key":"10.1002\/14651858.CD000553.pub3-BIB0117|cit117","first-page":"57","article-title":"Interpreting meta-analysis according to the adequacy of sample size. An example using isoniazid chemoprophylaxis for tuberculosis in purified protein derivative negative HIV-infected individuals","volume":"2","author":"Thorlund","year":"2010","journal-title":"Clinical Epidemiology"},{"key":"10.1002\/14651858.CD000553.pub3-BIB0118|cit118","unstructured":"Thorlund K Engstr\u00f8m J Wetterslev J Brok J Imberger G Gluud C User manual for Trial Sequential Analysis (TSA) ctu.dk\/tsa\/files\/tsa_manual.pdf"},{"key":"10.1002\/14651858.CD000553.pub3-BIB0119|cit119","doi-asserted-by":"publisher","first-page":"16","DOI":"10.1186\/1745-6215-8-16","article-title":"Practical methods for incorporating summary time-to-event data into meta-analysis","volume":"8","author":"Tierney","year":"2007","journal-title":"Trials"},{"issue":"11","key":"10.1002\/14651858.CD000553.pub3-BIB0120|cit120","doi-asserted-by":"publisher","first-page":"1680","DOI":"10.1136\/gutjnl-2015-309262","article-title":"UK Guidelines on the management of variceal haemorrhage in cirrhotic patients","volume":"64","author":"Tripathi","year":"2015","journal-title":"Gut"},{"key":"10.1002\/14651858.CD000553.pub3-BIB0121|cit121","unstructured":"TSA - Trial Sequential Analysis Copenhagen Trial Unit 2011"},{"issue":"164","key":"10.1002\/14651858.CD000553.pub3-BIB0122|cit122","doi-asserted-by":"publisher","first-page":"357","DOI":"10.1111\/1467-985X.00207","article-title":"The value of the aggregate data approach in meta-analysis with time-to-event outcomes","volume":"2","author":"Tudur","year":"2001","journal-title":"Journal of the Royal Statistical Society: Series A (Statistics in Society)"},{"issue":"16","key":"10.1002\/14651858.CD000553.pub3-BIB0123|cit123","doi-asserted-by":"crossref","first-page":"2303","DOI":"10.2165\/0003495-200868160-00004","article-title":"Variceal bleeding: pharmacological treatment and prophylactic strategies","volume":"68","author":"Villanueva","year":"2008","journal-title":"Drugs"},{"issue":"4","key":"10.1002\/14651858.CD000553.pub3-BIB0124|cit124","doi-asserted-by":"publisher","first-page":"346","DOI":"10.1097\/00000658-198610000-00002","article-title":"Splenopancreatic disconnection. Improved selectivity of distal splenorenal shunt","volume":"204","author":"Warren","year":"1986","journal-title":"Annals of Surgery"},{"issue":"1","key":"10.1002\/14651858.CD000553.pub3-BIB0125|cit125","doi-asserted-by":"publisher","first-page":"64","DOI":"10.1016\/j.jclinepi.2007.03.013","article-title":"Trial sequential analysis may establish when firm evidence is reached in cumulative meta-analysis","volume":"61","author":"Wetterslev","year":"2008","journal-title":"Journal of Clinical Epidemiology"},{"key":"10.1002\/14651858.CD000553.pub3-BIB0126|cit126","doi-asserted-by":"publisher","first-page":"86","DOI":"10.1186\/1471-2288-9-86","article-title":"Estimating required information size by quantifying diversity in a random-effects meta-analysis","volume":"9","author":"Wetterslev","year":"2009","journal-title":"BMC Medical Research Methodology"},{"issue":"1","key":"10.1002\/14651858.CD000553.pub3-BIB0127|cit127","doi-asserted-by":"publisher","first-page":"39","DOI":"10.1186\/s12874-017-0315-7","article-title":"Trial Sequential Analysis in systematic reviews with meta-analysis","volume":"17","author":"Wetterslev","year":"2017","journal-title":"BMC Medical Research Methodology"},{"issue":"22","key":"10.1002\/14651858.CD000553.pub3-BIB0128|cit128","doi-asserted-by":"publisher","first-page":"3337","DOI":"10.1002\/sim.1303","article-title":"Aggregate data meta-analysis with time-to-event outcomes","volume":"21","author":"Williamson","year":"2002","journal-title":"Statistics in Medicine"},{"issue":"47","key":"10.1002\/14651858.CD000553.pub3-BIB0129|cit129","doi-asserted-by":"publisher","first-page":"17941","DOI":"10.3748\/wjg.v20.i47.17941","article-title":"Risk factors for early rebleeding and mortality in acute variceal hemorrhage","volume":"20","author":"Zhao","year":"2014","journal-title":"World Journal of Gastroenterology"},{"issue":"5","key":"10.1002\/14651858.CD000553.pub3-BIB0130|cit130","doi-asserted-by":"publisher","first-page":"507","DOI":"10.1097\/MCG.0b013e31815576e6","article-title":"Transjugular intrahepatic portosystemic shunt versus endoscopic therapy in the secondary prophylaxis of variceal rebleeding in cirrhotic patients: meta-analysis update","volume":"42","author":"Zheng","year":"2008","journal-title":"Journal of Clinical Gastroenterology"},{"issue":"9","key":"10.1002\/14651858.CD000553.pub3-BIB0131|cit131","doi-asserted-by":"publisher","first-page":"1087","DOI":"10.1097\/CM9.0000000000000212","article-title":"Comparision between portosystemic shunts and endoscopic therapy for prevention of variceal re-bleeding: a systematic review and meta-analysis","volume":"132","author":"Zhou","year":"2019","journal-title":"Chinese Medical Journal"},{"issue":"4","key":"10.1002\/14651858.CD000553.pub3-BIB0132|cit132","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD000553","article-title":"Portosystemic shunts versus endoscopic therapy for variceal rebleeding in patients with cirrhosis","author":"Khan","year":"1997","journal-title":"Cochrane Database of Systematic Reviews"},{"issue":"4","key":"10.1002\/14651858.CD000553.pub3-BIB0133|cit133","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD000553.pub2","article-title":"Portosystemic shunts versus endoscopic therapy for variceal rebleeding in patients with cirrhosis","author":"Khan","year":"2006","journal-title":"Cochrane Database of Systematic Reviews"}],"container-title":["Cochrane Database of Systematic Reviews"],"original-title":[],"language":"en","deposited":{"date-parts":[[2024,2,25]],"date-time":"2024-02-25T11:50:21Z","timestamp":1708861821000},"score":1,"resource":{"primary":{"URL":"http:\/\/doi.wiley.com\/10.1002\/14651858.CD000553.pub3"}},"subtitle":[],"editor":[{"name":"Cochrane Hepato-Biliary Group","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2020,10,22]]},"references-count":133,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2020,10]]}},"URL":"https:\/\/doi.org\/10.1002\/14651858.cd000553.pub3","relation":{},"ISSN":["1465-1858"],"issn-type":[{"value":"1465-1858","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,10,22]]}}}