{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T11:40:05Z","timestamp":1792842005074,"version":"4.5.0"},"update-to":[{"DOI":"10.1002\/14651858.cd001456","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2012,11,14]],"date-time":"2012-11-14T00:00:00Z","timestamp":1352851200000}}],"reference-count":57,"publisher":"Wiley","issue":"11","content-domain":{"domain":["wiley.com","cochranelibrary.com"],"crossmark-restriction":true},"short-container-title":[],"DOI":"10.1002\/14651858.cd001456.pub2","type":"journal-article","created":{"date-parts":[[2012,11,9]],"date-time":"2012-11-09T00:26:25Z","timestamp":1352420785000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":119,"title":["Early versus delayed selective surfactant treatment for neonatal respiratory distress syndrome"],"prefix":"10.1002","volume":"2012","author":[{"given":"Felicia L","family":"Bahadue","sequence":"first","affiliation":[{"name":"University of Vermont; Burlington Vermont USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roger","family":"Soll","sequence":"additional","affiliation":[{"name":"University of Vermont; Division of Neonatal-Perinatal Medicine; Fletcher Allen Health Care, Smith 552A 111 Colchester Avenue Burlington Vermont USA 05401"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2012,11,14]]},"reference":[{"key":"10.1002\/14651858.CD001456.pub2-BIB0001|cit1","first-page":"Doc. No. 28","article-title":"Early or selective surfactant (Colfosceril Palmitate, Exosurf) for intubated babies at 26 to 29 weeks gestation: a European double-blind trial with sequential analysis","author":"European Exosurf Study Group","year":"1992","journal-title":"Online Journal of Current Clinical Trials"},{"issue":"5","key":"10.1002\/14651858.CD001456.pub2-BIB0002|cit2","doi-asserted-by":"crossref","first-page":"1153","DOI":"10.1542\/peds.102.5.1153","article-title":"Early versus late surfactant treatment in preterm infants of 27 to 32 weeks' gestational age: a multicenter controlled clinical trial","volume":"102","author":"Gortner","year":"1998","journal-title":"Pediatrics"},{"issue":"4","key":"10.1002\/14651858.CD001456.pub2-BIB0003|cit3","doi-asserted-by":"crossref","first-page":"654","DOI":"10.1111\/j.1651-2227.2008.01216.x","article-title":"Neurodevelopmental outcome and pulmonary morbidity two years after early versus late surfactant treatment: does it really differ?","volume":"98","author":"Hentschel","year":"2009","journal-title":"Acta Paediatroca"},{"issue":"1-3","key":"10.1002\/14651858.CD001456.pub2-BIB0004|cit4","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1016\/0378-3782(92)90164-C","article-title":"A prospective randomized trial of early versus late administration of a single dose of surfactant-TA","volume":"29","author":"Konishi","year":"1992","journal-title":"Early Human Development"},{"issue":"3","key":"10.1002\/14651858.CD001456.pub2-BIB0005|cit5","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1080\/jmf.14.3.187.196","article-title":"Clinical course of premature infants intubated in the delivery room, submitted or not to porcine-derived lung surfactant therapy within the first hour of life","volume":"14","author":"Lefort","year":"2003","journal-title":"Journal of Maternal-Fetal & Neonatal Medicine"},{"issue":"8832","key":"10.1002\/14651858.CD001456.pub2-BIB0006|cit6","doi-asserted-by":"crossref","first-page":"1363","DOI":"10.1016\/0140-6736(92)92557-V","article-title":"Early versus delayed neonatal administration of a synthetic surfactant - the judgement of OSIRIS. The OSIRIS Collaborative Group (open study of infants at high risk of or with respiratory insufficiency - the role of surfactant","volume":"340","author":"The OSIRIS Collaborative Group","year":"1992","journal-title":"Lancet"},{"issue":"10","key":"10.1002\/14651858.CD001456.pub2-BIB0007|cit7","doi-asserted-by":"crossref","first-page":"1483","DOI":"10.1007\/s00134-002-1440-1","article-title":"Early versus delayed surfactant administration in extremely premature neonates with respiratory distress syndrome ventilated by high-frequency oscillatory ventilation","volume":"28","author":"Plavka","year":"2002","journal-title":"Intensive Care Medicine"},{"issue":"6","key":"10.1002\/14651858.CD001456.pub2-BIB0008|cit8","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1515\/jpme.1996.24.6.609","article-title":"Prophylaxis of respiratory distress syndrome by treatment with modified porcine surfactant at birth: a multicentre prospective randomized trial","volume":"24","author":"Bevilacqua","year":"1996","journal-title":"Journal of Perinatal Medicine"},{"issue":"Suppl 1","key":"10.1002\/14651858.CD001456.pub2-BIB0009|cit9","first-page":"47","article-title":"Use of surfactant for prophylaxis versus rescue treatment of respiratory distress syndrome: experience from an Italian-Bulgarian trial","volume":"68","author":"Bevilacqua","year":"1997","journal-title":"Acta Bio-Medica de L'Ateneo parmense"},{"issue":"3","key":"10.1002\/14651858.CD001456.pub2-BIB0010|cit10","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1542\/peds.87.3.377","article-title":"Bovine surfactant replacement therapy in neonates of less than 30 weeks' gestation: a randomized controlled trial of prophylaxis vs treatment","volume":"87","author":"Dunn","year":"1991","journal-title":"Pediatrics"},{"issue":"5","key":"10.1002\/14651858.CD001456.pub2-BIB0011|cit11","doi-asserted-by":"crossref","first-page":"e1069","DOI":"10.1542\/peds.2010-3848","article-title":"Randomized trial comparing 3 approaches to the initial respiratory management of preterm neonates","volume":"128","author":"Dunn","year":"2011","journal-title":"Pediatrics"},{"issue":"6","key":"10.1002\/14651858.CD001456.pub2-BIB0012|cit12","doi-asserted-by":"crossref","first-page":"768","DOI":"10.1542\/peds.92.6.768","article-title":"Comparison of prophylaxis and rescue treatment with Curosurf in neonates less than 30 weeks gestation: a randomized trial","volume":"92","author":"Egberts","year":"1993","journal-title":"Pediatrics"},{"issue":"6","key":"10.1002\/14651858.CD001456.pub2-BIB0013|cit13","first-page":"804","article-title":"Early surfactant for neonates with mild to moderate respiratory distress syndrome: a multicenter, randomized trial","volume":"144","author":"Escobedo","year":"2004","journal-title":"Journal of Pediatrics"},{"issue":"3","key":"10.1002\/14651858.CD001456.pub2-BIB0014|cit14","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1080\/080352501300067631","article-title":"Early administration of the second dose of surfactant (beractant) in the treatment of severe hyaline membrane disease","volume":"90","author":"Figueras-Aloy","year":"2001","journal-title":"Acta Pediatrica"},{"issue":"9803","key":"10.1002\/14651858.CD001456.pub2-BIB0015|cit15","doi-asserted-by":"crossref","first-page":"1627","DOI":"10.1016\/S0140-6736(11)60986-0","article-title":"Avoidance of mechanical ventilation by surfactant treatment of spontaneously breathing preterm infants (AMV): an open-label, randomised, controlled trial","volume":"378","author":"G\u00f6pel","year":"2011","journal-title":"Lancet"},{"issue":"1","key":"10.1002\/14651858.CD001456.pub2-BIB0016|cit16","first-page":"23","article-title":"Administration of exogenous surfactant in very low birth weight infants with RDS","volume":"38","author":"Iar\u016dkova","year":"1999","journal-title":"Akuserstvo i Ginekologija"},{"issue":"1","key":"10.1002\/14651858.CD001456.pub2-BIB0017|cit17","first-page":"90","article-title":"Prophylactic administration of calf lung surfactant extract is more effective than early treatment of respiratory distress syndrome in neonates of 29 through 32 weeks' gestation","volume":"92","author":"Kattwinkel","year":"1993","journal-title":"Pediatrics"},{"issue":"2 Pt 1","key":"10.1002\/14651858.CD001456.pub2-BIB0018|cit18","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1542\/peds.106.2.282","article-title":"High-versus low-threshold surfactant retreatment for neonatal respiratory distress syndrome","volume":"106","author":"Kattwinkel","year":"2000","journal-title":"Pediatrics"},{"issue":"13","key":"10.1002\/14651858.CD001456.pub2-BIB0019|cit19","doi-asserted-by":"crossref","first-page":"865","DOI":"10.1056\/NEJM199103283241301","article-title":"A comparison of surfactant as immediate prophylaxis and as rescue therapy in newborns of less than 30 weeks' gestation","volume":"324","author":"Kendig","year":"1991","journal-title":"New England Journal of Medicine"},{"issue":"6","key":"10.1002\/14651858.CD001456.pub2-BIB0020|cit20","first-page":"556","article-title":"Early administration of the second surfactant dose in preterm infants with severe respiratory distress syndrome","volume":"51","author":"K\u00f6ksal","year":"2009","journal-title":"Turkis Journal of Pediatrics"},{"issue":"4 Pt 1","key":"10.1002\/14651858.CD001456.pub2-BIB0021|cit21","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1016\/S0022-3476(05)83387-6","article-title":"Randomized, placebo-controlled trial of human surfactant given at birth vs rescue administration in very low birthweight infants with lung immaturity","volume":"118","author":"Merritt","year":"1991","journal-title":"Journal of Pediatrics"},{"issue":"7","key":"10.1002\/14651858.CD001456.pub2-BIB0022|cit22","doi-asserted-by":"crossref","first-page":"700","DOI":"10.1056\/NEJMoa072788","article-title":"Nasal CPAP or intubation at birth for very preterm infants","volume":"358","author":"Morley","year":"2008","journal-title":"New England Journal of Medicine"},{"issue":"3","key":"10.1002\/14651858.CD001456.pub2-BIB0023|cit23","doi-asserted-by":"crossref","first-page":"E30","DOI":"10.1542\/peds.106.3.e30","article-title":"Targeted early rescue surfactant in ventilated preterm infants using the click test","volume":"106","author":"Osborn","year":"2000","journal-title":"Pediatrics"},{"issue":"11","key":"10.1002\/14651858.CD001456.pub2-BIB0024|cit24","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1038\/sj.jp.7211381","article-title":"Surfactant administration by transient intubation in infants 29 to 35 weeks' gestation with respiratory distress syndrome decreases the likelihood of later mechanical ventilation: a randomized controlled trial","volume":"25","author":"Reininger","year":"2005","journal-title":"Journal of Perinatology"},{"issue":"1","key":"10.1002\/14651858.CD001456.pub2-BIB0025|cit25","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1542\/peds.2007-3501","article-title":"Very early surfactant without mandatory ventilation in premature infants treated with early continuous positive airway pressure: a randomized, controlled trial","volume":"123","author":"Rojas","year":"2009","journal-title":"Pediatrics"},{"issue":"6","key":"10.1002\/14651858.CD001456.pub2-BIB0026|cit26","doi-asserted-by":"crossref","first-page":"e1402","DOI":"10.1542\/peds.2009-2131","article-title":"Prophylactic or early selective surfactant combined with nCPAP in very preterm infants","volume":"125","author":"Sandri","year":"2010","journal-title":"Pediatrics"},{"issue":"21","key":"10.1002\/14651858.CD001456.pub2-BIB0027|cit27","doi-asserted-by":"crossref","first-page":"1970","DOI":"10.1056\/NEJMoa0911783","article-title":"Early CPAP versus surfactant in extremely preterm infants","volume":"362","author":"Finer","year":"2010","journal-title":"New England Journal of Medicine"},{"issue":"2","key":"10.1002\/14651858.CD001456.pub2-BIB0028|cit28","doi-asserted-by":"crossref","first-page":"E24","DOI":"10.1542\/peds.103.2.e24","article-title":"Nasal continuous positive airway pressure and early surfactant therapy for respiratory distress syndrome in newborns of less than 30 weeks' gestation","volume":"103","author":"Verder","year":"1999","journal-title":"Pediatrics"},{"issue":"8","key":"10.1002\/14651858.CD001456.pub2-BIB0029|cit29","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1111\/j.1651-2227.1995.tb13792.x","article-title":"Porcine surfactant replacement therapy in newborns of 25-31 weeks' gestation: a randomized multicentre trial of prophylaxis versus rescue with multiple low doses","volume":"84","author":"Walti","year":"1995","journal-title":"Acta Paediatrica"},{"issue":"10","key":"10.1002\/14651858.CD001456.pub2-BIB0030|cit30","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD008310.pub2","article-title":"Nebulised surfactant for prevention of morbidity and mortality in preterm infants with or at risk of respiratory distress syndrome","author":"Abdel-Latif","year":"2010","journal-title":"Cochrane Database of Systematic Reviews"},{"issue":"7","key":"10.1002\/14651858.CD001456.pub2-BIB0031|cit31","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD008309.pub2","article-title":"Laryngeal mask airway surfactant administration for prevention of morbidity and mortality in preterm infants with or at risk of respiratory distress syndrome","author":"Abdel-Latif","year":"2011","journal-title":"Cochrane Database of Systematic Reviews"},{"issue":"3","key":"10.1002\/14651858.CD001456.pub2-BIB0032|cit32","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD008311.pub2","article-title":"Pharyngeal instillation of surfactant before the first breath for prevention of morbidity and mortality in preterm infants at risk of respiratory distress syndrome","author":"Abdel-Latif","year":"2011","journal-title":"Cochrane Database of Systematic Reviews"},{"issue":"3","key":"10.1002\/14651858.CD001456.pub2-BIB0033|cit33","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD000065.pub2","article-title":"Prophylactic corticosteroids for preterm delivery","author":"Crowley","year":"2006","journal-title":"Cochrane Database of Systematic Reviews"},{"issue":"1","key":"10.1002\/14651858.CD001456.pub2-BIB0034|cit34","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD003486","article-title":"Therapeutic lung lavage for meconium aspiration syndrome in newborn infants (Protocol)","author":"Dargaville","year":"2002","journal-title":"Cochrane Database of Systematic Reviews"},{"issue":"3","key":"10.1002\/14651858.CD001456.pub2-BIB0035|cit35","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD002054.pub2","article-title":"Surfactant for meconium aspiration syndrome in full term\/near term infants","author":"Shahed","year":"2007","journal-title":"Cochrane Database of Systematic Reviews"},{"issue":"3","key":"10.1002\/14651858.CD001456.pub2-BIB0036|cit36","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1016\/S0022-3476(83)80673-8","article-title":"Surfactant function in respiratory distress syndrome","volume":"102","author":"Ikegami","year":"1983","journal-title":"Journal of Pediatrics"},{"issue":"2","key":"10.1002\/14651858.CD001456.pub2-BIB0037|cit37","doi-asserted-by":"crossref","first-page":"508","DOI":"10.1016\/0002-9378(93)90483-Y","article-title":"Beneficial effects of the combined use of prenatal corticosteroids and postnatal surfactant in preterm infants","volume":"168","author":"Jobe","year":"1993","journal-title":"American Journal of Obstetrics and Gynecology"},{"issue":"4 Pt 1","key":"10.1002\/14651858.CD001456.pub2-BIB0038|cit38","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1203\/00006450-197804000-00001","article-title":"Lung surfactant and the pathogenesis of neonatal bronchiolar lesions induced by artificial ventilation","volume":"12","author":"Nilsson","year":"1978","journal-title":"Pediatric Research"},{"issue":"4","key":"10.1002\/14651858.CD001456.pub2-BIB0039|cit39","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD006069.pub3","article-title":"Protein containing synthetic surfactant versus animal derived surfactant extract for the prevention and treatment of respiratory distress syndrome","author":"Pfister","year":"2007","journal-title":"Cochrane Database of Systematic Reviews"},{"issue":"4","key":"10.1002\/14651858.CD001456.pub2-BIB0040|cit40","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD006180.pub2","article-title":"Protein-containing synthetic surfactant versus protein-free synthetic surfactant for the prevention and treatment of respiratory distress syndrome","author":"Pfister","year":"2009","journal-title":"Cochrane Database of Systematic Reviews"},{"issue":"4","key":"10.1002\/14651858.CD001456.pub2-BIB0041|cit41","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1164\/ajrccm\/142.4.749","article-title":"The role of surfactant-associated proteins","volume":"142","author":"Possmayer","year":"1990","journal-title":"American Review of Respiratory Disease"},{"key":"10.1002\/14651858.CD001456.pub2-BIB0042|cit42","unstructured":"The Nordic Cochrane Centre, The Cochrane Collaboration Review Manager (RevMan) 2011"},{"issue":"3","key":"10.1002\/14651858.CD001456.pub2-BIB0043|cit43","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD000510.pub2","article-title":"Prophylactic versus selective use of surfactant in preventing morbidity and mortality in preterm infants","author":"Rojas-Reyes","year":"2012","journal-title":"Cochrane Database of Systematic Reviews"},{"issue":"2 Pt 1","key":"10.1002\/14651858.CD001456.pub2-BIB0044|cit44","first-page":"L210","article-title":"Pulmonary SP-A enhances adsorption and appears to induce surface sorting of lipid extract surfactant","volume":"263","author":"Sch\u00fcrch","year":"1992","journal-title":"American Journal of Physiology"},{"issue":"2","key":"10.1002\/14651858.CD001456.pub2-BIB0045|cit45","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD007836","article-title":"Animal derived surfactant extract for treatment of respiratory distress syndrome","author":"Seger","year":"2009","journal-title":"Cochrane Database of Systematic Reviews"},{"key":"10.1002\/14651858.CD001456.pub2-BIB0046|cit46","volume-title":"Effective Care of the Newborn Infant","author":"Sinclair","year":"1992"},{"key":"10.1002\/14651858.CD001456.pub2-BIB0047|cit47","doi-asserted-by":"crossref","unstructured":"Singh N Hawley KL Viswanathan K Efficacy of porcine versus bovine surfactants for preterm newborns with respiratory distress syndrome: systematic review and meta-analysis Pediatrics 2011 e1588 95","DOI":"10.1542\/peds.2011-1395"},{"key":"10.1002\/14651858.CD001456.pub2-BIB0048|cit48","first-page":"325","article-title":"Respiratory distress syndrome","volume-title":"Effective Care of the Newborn Infant","author":"Soll","year":"1992"},{"issue":"4","key":"10.1002\/14651858.CD001456.pub2-BIB0049|cit49","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD000511","article-title":"Prophylactic animal derived surfactant extract for preventing morbidity and mortality in preterm infants","author":"Soll","year":"1997","journal-title":"Cochrane Database of Systematic Reviews"},{"issue":"2","key":"10.1002\/14651858.CD001456.pub2-BIB0050|cit50","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD001149","article-title":"Synthetic surfactant for respiratory distress syndrome in preterm infants","author":"Soll","year":"2000","journal-title":"Cochrane Database of Systematic Reviews"},{"issue":"2","key":"10.1002\/14651858.CD001456.pub2-BIB0051|cit51","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD000144","article-title":"Natural surfactant extract versus synthetic surfactant for neonatal respiratory distress syndrome","author":"Soll","year":"2001","journal-title":"Cochrane Database of Systematic Reviews"},{"issue":"1","key":"10.1002\/14651858.CD001456.pub2-BIB0052|cit52","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD000141.pub2","article-title":"Multiple versus single doses of exogenous surfactant for the prevention or treatment of neonatal respiratory distress syndrome","author":"Soll","year":"2009","journal-title":"Cochrane Database of Systematic Reviews"},{"issue":"1","key":"10.1002\/14651858.CD001456.pub2-BIB0053|cit53","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD001079.pub2","article-title":"Prophylactic protein free synthetic surfactant for preventing morbidity and mortality in preterm infants","author":"Soll","year":"2010","journal-title":"Cochrane Database of Systematic Reviews"},{"issue":"4","key":"10.1002\/14651858.CD001456.pub2-BIB0054|cit54","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD003063.pub3","article-title":"Early surfactant administration with brief ventilation vs. selective surfactant and continued mechanical ventilation for preterm infants with or at risk for respiratory distress syndrome","author":"Stevens","year":"2007","journal-title":"Cochrane Database of Systematic Reviews"},{"issue":"2","key":"10.1002\/14651858.CD001456.pub2-BIB0055|cit55","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD008155.pub2","article-title":"Surfactant for bacterial pneumonia in late preterm and term infants","author":"Tan","year":"2012","journal-title":"Cochrane Database of Systematic Reviews"},{"issue":"4","key":"10.1002\/14651858.CD001456.pub2-BIB0056|cit56","doi-asserted-by":"crossref","first-page":"931","DOI":"10.1152\/physrev.1997.77.4.931","article-title":"Immunomodulatory functions of surfactant","volume":"77","author":"Wright","year":"1997","journal-title":"Physiological Reviews"},{"issue":"4","key":"10.1002\/14651858.CD001456.pub2-BIB0057|cit57","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD001456","article-title":"Early versus delayed selective surfactant treatment for neonatal respiratory distress syndrome","author":"Soll","year":"1999","journal-title":"Cochrane Database of Systematic Reviews"}],"container-title":["Cochrane Database of Systematic Reviews"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/onlinelibrary.wiley.com\/wol1\/doi\/10.1002\/14651858.CD001456.pub2\/fullpdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,10,2]],"date-time":"2024-10-02T15:32:16Z","timestamp":1727883136000},"score":1,"resource":{"primary":{"URL":"http:\/\/doi.wiley.com\/10.1002\/14651858.CD001456.pub2"}},"subtitle":[],"editor":[{"name":"Cochrane Neonatal Group","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2012,11,14]]},"references-count":57,"journal-issue":{"issue":"11","published-online":{"date-parts":[[2012,11]]}},"URL":"https:\/\/doi.org\/10.1002\/14651858.cd001456.pub2","relation":{},"ISSN":["1465-1858"],"issn-type":[{"value":"1465-1858","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,11,14]]}}}