{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T11:09:45Z","timestamp":1790075385361,"version":"4.0.1"},"reference-count":42,"publisher":"Wiley","issue":"3","content-domain":{"domain":["wiley.com","cochranelibrary.com"],"crossmark-restriction":true},"short-container-title":[],"DOI":"10.1002\/14651858.cd001986","type":"journal-article","created":{"date-parts":[[2003,11,20]],"date-time":"2003-11-20T22:33:39Z","timestamp":1069367619000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":45,"title":["Intravesical Bacillus Calmette-Gu\u00e9rin in Ta and T1 bladder cancer"],"prefix":"10.1002","volume":"2010","author":[{"given":"Mike","family":"Shelley","sequence":"first","affiliation":[{"name":"Velindre NHS Trust; Cochrane Prostatic Diseases and Urological Cancers Unit, Research Dept; Velindre Road Whitchurch Cardiff Wales UK CF4 7XL"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J B","family":"Court","sequence":"additional","affiliation":[{"name":"Cardiff Wales UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H","family":"Kynaston","sequence":"additional","affiliation":[{"name":"Cardiff Wales UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timothy J","family":"Wilt","sequence":"additional","affiliation":[{"name":"VAMC; General Internal Medicine (111-0); One Veterans Drive Minneapolis Minnesota USA 55417"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Reg","family":"Fish","sequence":"additional","affiliation":[{"name":"Velindre Hospital; Clinical Oncology; Whitchurch Cardiff UK CF4 7XL"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Malcolm","family":"Mason","sequence":"additional","affiliation":[{"name":"Velindre Hospital; Clinical Oncology; Whitchurch Cardiff UK CF4 7XL"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2000,10,23]]},"reference":[{"key":"10.1002\/14651858.CD001986-BIB0001|cit1","doi-asserted-by":"crossref","first-page":"962","DOI":"10.1016\/S0022-5347(01)65673-8","article-title":"A randomized multicenter trial of adjuvant therapy in superficial bladder cancer: transurethral resection only versus transurethral resection plus mitomycin C versus transurethral resection plus bacillus Calmette-Gu\u00e9rin","volume":"156","author":"Krege","year":"1996","journal-title":"Journal of Urology"},{"key":"10.1002\/14651858.CD001986-BIB0002|cit2","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/S0022-5347(17)46972-2","article-title":"Bacillus Calmette-Gu\u00e9rin immunotherapy for bladder cancer","volume":"134","author":"Lamm","year":"1985","journal-title":"Journal of Urology"},{"key":"10.1002\/14651858.CD001986-BIB0003|cit3","first-page":"137","article-title":"Intravesical Bacillus Clamette-Gu\u00e9rin prophylactic treatment for superficial bladder tumors: Results of a controlled prospective study","volume":"45","author":"Melekos","year":"1990","journal-title":"Urology International"},{"key":"10.1002\/14651858.CD001986-BIB0004|cit4","first-page":"69","article-title":"Low dose BCG therapy in superficial bladder cancer: a clinicopathological prospective study","volume-title":"Immnunotherapy of Urological Tumours: International Society of Urological Reports","author":"Pagano","year":"1990"},{"key":"10.1002\/14651858.CD001986-BIB0005|cit5","first-page":"47","article-title":"Intravesical administration of bacillus Calmette-Gu\u00e9rin in patients with recurrent superficial carcinoma of the urinary bladder: Report of a prospective randomized trial","volume":"69","author":"Pinsky","year":"1985","journal-title":"Cancer Treatment Reports"},{"issue":"7","key":"10.1002\/14651858.CD001986-BIB0006|cit6","first-page":"99","article-title":"Intravesical bacillus Calmette-Gu\u00e9rin (BCG) in the treatment of superficial bladder cancer","volume":"81","author":"Yamamoto","year":"1990","journal-title":"Japanese Journal of Urology"},{"key":"10.1002\/14651858.CD001986-BIB0007|cit7","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1200\/JCO.1987.5.3.441","article-title":"A prospective randomised trial of maintenance versus nonmaintenance intravesical BCG therapy for superficial bladder cancer","volume":"5","author":"Badalament","year":"1987","journal-title":"Journal of Clinical Oncology"},{"issue":"5","key":"10.1002\/14651858.CD001986-BIB0008|cit8","first-page":"503","article-title":"Low dose BCG regimen in the treatment of superficial bladder cancer","volume":"43","author":"Bassi","year":"1990","journal-title":"Arch. Esp. de Urol."},{"key":"10.1002\/14651858.CD001986-BIB0009|cit9","unstructured":"Camacho C Pinsky C Kerr D Whitmore W Oettgen H Treatment of superficial bladder cancer with intravesical BCG American Society of Clinical Oncology 1980 359"},{"issue":"5","key":"10.1002\/14651858.CD001986-BIB0010|cit10","first-page":"435","article-title":"Results of the treatment of superficial bladder tumours by transurethral resection alone or transurethral resection followed by endovesical instillation of Calmette-Gu\u00e9rin bacillus","volume":"24","author":"Chopin","year":"1990","journal-title":"Annales D'Urolgie"},{"key":"10.1002\/14651858.CD001986-BIB0011|cit11","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1097\/00005392-199707000-00017","article-title":"The treated natural history of high risk superficial bladder cancer: 15 year outcome","volume":"158","author":"Cookson","year":"1997","journal-title":"Journal of Urology"},{"key":"10.1002\/14651858.CD001986-BIB0012|cit12","doi-asserted-by":"crossref","first-page":"1323","DOI":"10.1002\/1097-0142(19830401)51:7<1323::AID-CNCR2820510724>3.0.CO;2-2","article-title":"Effect of intravesical bacillus Calmette-Gu\u00e9rin (BCG) on carcinoma in situ of the bladder","volume":"51","author":"Herr","year":"1983","journal-title":"Cancer"},{"issue":"2","key":"10.1002\/14651858.CD001986-BIB0013|cit13","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/0090-4295(85)90525-4","article-title":"Experience with intravesical bacillus Calmette-Gu\u00e9rin therapy of superficial bladder tumours","volume":"25","author":"Herr","year":"1985","journal-title":"Urology"},{"key":"10.1002\/14651858.CD001986-BIB0014|cit14","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/S0022-5347(17)45604-7","article-title":"Long-term effect of intravesical bacillus Calmette-Gu\u00e9rin on flat carcinoma in situ of the bladder","volume":"135","author":"Herr","year":"1986","journal-title":"Journal of Urology"},{"key":"10.1002\/14651858.CD001986-BIB0015|cit15","doi-asserted-by":"crossref","first-page":"1450","DOI":"10.1200\/JCO.1988.6.9.1450","article-title":"Bacillus Calmette-Gu\u00e9rin therapy alters the progression of superficial bladder cancer","volume":"6","author":"Herr","year":"1988","journal-title":"Journal of Clinical Oncology"},{"issue":"6 June","key":"10.1002\/14651858.CD001986-BIB0016|cit16","doi-asserted-by":"crossref","first-page":"1404","DOI":"10.1200\/JCO.1995.13.6.1404","article-title":"Intravesical bacillus Calmette-Gu\u00e9rin therapy prevents tumour progression and death from superficial bladder cancer: ten-year follow-up of a prospective randomized trial","volume":"13","author":"Herr","year":"1995","journal-title":"Journal of Clinical Oncology"},{"key":"10.1002\/14651858.CD001986-BIB0017|cit17","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1016\/S0022-5347(17)41701-0","article-title":"Prophylactic maltose tetrapalmitate and bacillus Calmette-Gu\u00e9rin immunotherapy of recurrent superficial bladder tumours: preliminary report","volume":"140","author":"Ibrahiem","year":"1988","journal-title":"The Journal of Urology"},{"key":"10.1002\/14651858.CD001986-BIB0018|cit18","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/S0022-5347(17)55282-9","article-title":"Bacillus Calmette-Gu\u00e9rin immunotherapy of superficial bladder cancer","volume":"124","author":"Lamm","year":"1980","journal-title":"The Journal of Urology"},{"key":"10.1002\/14651858.CD001986-BIB0019|cit19","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1002\/1097-0142(19810701)48:1<82::AID-CNCR2820480117>3.0.CO;2-Z","article-title":"BCG immunotherapy of bladder cancer: inhibition of tumour recurrence and associated immune responses","volume":"48","author":"Lamm","year":"1981","journal-title":"Cancer"},{"key":"10.1002\/14651858.CD001986-BIB0020|cit20","first-page":"315","article-title":"Intravesical and percutaneous BCG immunotherapy of recurrent superficial bladder cancer","volume-title":"Immunotherapy of Human Cancer","author":"Lamm","year":"1982"},{"key":"10.1002\/14651858.CD001986-BIB0021|cit21","doi-asserted-by":"crossref","first-page":"931","DOI":"10.1016\/S0022-5347(17)53283-8","article-title":"Bladder cancer immunotherapy","volume":"128","author":"Lamm","year":"1982","journal-title":"The Journal of Urology"},{"key":"10.1002\/14651858.CD001986-BIB0022|cit22","first-page":"253","article-title":"Low-dose BCG-Pasteur strain in the treatment of superficial bladder cancer: preliminary results","volume-title":"EORTC Genitourinary Group Monograph 6: BCG in Superifial Bladder Cancer","author":"Pagano","year":"1989"},{"issue":"July","key":"10.1002\/14651858.CD001986-BIB0023|cit23","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/S0022-5347(17)37707-8","article-title":"A low dose bacillus Calmette-Gu\u00e9rin regimen in superficial bladder cancer therapy: is it effective?","volume":"146","author":"Pagano","year":"1991","journal-title":"The Journal of Urology"},{"key":"10.1002\/14651858.CD001986-BIB0024|cit24","first-page":"309","article-title":"Treatment of superficial bladder cancer with intravesical BCG","volume-title":"Immunotherapy of Human Cancer","author":"Pinsky","year":"1982"},{"key":"10.1002\/14651858.CD001986-BIB0025|cit25","first-page":"27","article-title":"Prospective randomized study of adjuvant therapy after complete resection of superficial bladder cancer; mitomycin C vs BCG Connaught vs TUR alone","volume-title":"International Society of Urological Reports: Immunotherapy of urological Tumours","author":"Rubben","year":"1990"},{"issue":"34","key":"10.1002\/14651858.CD001986-BIB0026|cit26","first-page":"1851","article-title":"Adjuvant BCG immunotherapy in the treatment of superficial bladder tumours","volume":"134","author":"Somogyi","year":"1993","journal-title":"Orvosi Hetilap"},{"key":"10.1002\/14651858.CD001986-BIB0027|cit27","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/1043-4666(90)90013-J","article-title":"Detection of urinary TNF, IL1, and IL2 after local BCG immunotherapy for bladder carcinoma","volume":"2","author":"Bohle","year":"1990","journal-title":"Cytokine"},{"key":"10.1002\/14651858.CD001986-BIB0028|cit28","first-page":"129","article-title":"The role of surgery in the multimodality treatment of bladder cancer","volume-title":"Cancer Surveys: Bladder Cancer","volume":"31","author":"Coptcoat","year":"1998"},{"key":"10.1002\/14651858.CD001986-BIB0029|cit29","first-page":"435","article-title":"BCG-(RIVM) versus mitomycin intravesical therapy in patients with superficial bladder cancer","volume":"Alan R Liss Inc","author":"Debruyne","year":"1989","journal-title":"Therapeutic Progress in Urologic Cancers"},{"key":"10.1002\/14651858.CD001986-BIB0030|cit30","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1111\/j.1464-410X.1994.tb07548.x","article-title":"Marker tumour response to Evans and Pasteur bacille Calmette-Gu\u00e9rin in multiple recurrent pTa\/pT1 bladder tumours: report from the Medical Research Council Subgroup on Superficial Bladder Cancer (Urological Cancer Working Party)","volume":"73","author":"Fellows","year":"1994","journal-title":"British Journal of Urology"},{"issue":"22nd January","key":"10.1002\/14651858.CD001986-BIB0031|cit31","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1136\/bmj.308.6923.257","article-title":"Proposal for changes in cystoscopic follow up of patients with bladder cancer and adjuvant intravesical chemotherapy","volume":"308","author":"Hall","year":"1994","journal-title":"British Medical Journal"},{"key":"10.1002\/14651858.CD001986-BIB0032|cit32","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/S0022-5347(17)43125-9","article-title":"Single course versus maintenance Bacillus Calmette-Gu\u00e9rin therapy for superficial bladder tumours: a prospective, randomized trial","volume":"138","author":"Hudson","year":"1987","journal-title":"J Urol"},{"issue":"11","key":"10.1002\/14651858.CD001986-BIB0033|cit33","doi-asserted-by":"crossref","first-page":"1840","DOI":"10.1016\/0959-8049(95)00287-S","article-title":"Factors affecting recurrence and progression in superficial bladder tumours","volume":"31A","author":"Kurth","year":"1995","journal-title":"European Journal of Cancer"},{"key":"10.1002\/14651858.CD001986-BIB0034|cit34","doi-asserted-by":"crossref","first-page":"738","DOI":"10.1016\/S0022-5347(17)38439-2","article-title":"Propective randomized comparison of intravesical with percutaneous bacillus Calmette-Guerin versus intravesical bacillus Calmette-Gu\u00e9rin in superficial bladder cancer","volume":"145","author":"Lamm","year":"1991","journal-title":"Journal of Urology"},{"key":"10.1002\/14651858.CD001986-BIB0035|cit35","first-page":"947","article-title":"BCG immunotherapy for carcinoma in situ of the bladder","volume":"9","author":"Lamm","year":"1995","journal-title":"Oncology"},{"key":"10.1002\/14651858.CD001986-BIB0036|cit36","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1016\/S0022-5347(17)58737-6","article-title":"Intracavitary bacillus Calmette Gu\u00e9rin in the treatment of superficial bladder tumours","volume":"137","author":"Morales","year":"1976","journal-title":"Journal of Urology"},{"key":"10.1002\/14651858.CD001986-BIB0037|cit37","first-page":"2815","article-title":"Extracting summary statistics to perform meta-analyses of the published literature for survival endpoints","volume-title":"Statistics in Medicine","volume":"17","author":"Parmar","year":"1998"},{"issue":"16","key":"10.1002\/14651858.CD001986-BIB0038|cit38","doi-asserted-by":"crossref","first-page":"1129","DOI":"10.1056\/NEJM199004193221607","article-title":"Biology and management of bladder cancer","volume":"322","author":"Raghavan","year":"1990","journal-title":"New England Journal of Medicine"},{"key":"10.1002\/14651858.CD001986-BIB0039|cit39","doi-asserted-by":"crossref","first-page":"1697","DOI":"10.1016\/S0022-5347(05)68208-0","article-title":"Bladder cancer clinical guidelines panel summary report on the management of nonmuscle invasive bladder cancer (stages Ta, T1 and TIS)","volume":"162","author":"Smith","year":"1999","journal-title":"Journal of Urology"},{"key":"10.1002\/14651858.CD001986-BIB0040|cit40","first-page":"125","article-title":"Bacillus Calmette-Gu\u00e9rin (BCG) for transitional cell carcinoma of the bladder","volume-title":"Clinical Management of Bladder Cancer","author":"Meijden","year":"1999"},{"key":"10.1002\/14651858.CD001986-BIB0041|cit41","first-page":"8","article-title":"Cancer Statistics, 1995","volume":"45","author":"Wingo","year":"1995","journal-title":"CA"},{"key":"10.1002\/14651858.CD001986-BIB0042|cit42","article-title":"Pathology of Bladder Cancer","volume-title":"Comprehensive Textbook of Genitourinary Oncology","author":"Young","year":"1996"}],"container-title":["Cochrane Database of Systematic Reviews"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full\/10.1002\/14651858.CD001986","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T05:31:37Z","timestamp":1783661497000},"score":1,"resource":{"primary":{"URL":"http:\/\/doi.wiley.com\/10.1002\/14651858.CD001986"}},"subtitle":[],"editor":[{"name":"Cochrane Urology Group","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2000,10,23]]},"references-count":42,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2010,3]]}},"URL":"https:\/\/doi.org\/10.1002\/14651858.cd001986","relation":{},"ISSN":["1465-1858"],"issn-type":[{"value":"1465-1858","type":"electronic"}],"subject":[],"published":{"date-parts":[[2000,10,23]]}}}