{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T13:09:29Z","timestamp":1791378569629,"version":"4.3.2"},"update-to":[{"DOI":"10.1002\/14651858.cd002118.pub5","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2022,5,19]],"date-time":"2022-05-19T00:00:00Z","timestamp":1652918400000}}],"reference-count":146,"publisher":"Wiley","issue":"6","content-domain":{"domain":["wiley.com","cochranelibrary.com"],"crossmark-restriction":true},"short-container-title":[],"DOI":"10.1002\/14651858.cd002118.pub6","type":"journal-article","created":{"date-parts":[[2022,5,19]],"date-time":"2022-05-19T13:14:59Z","timestamp":1652966099000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":89,"title":["Cleavage-stage versus blastocyst-stage embryo transfer in assisted reproductive technology"],"prefix":"10.1002","volume":"2022","author":[{"given":"Demi\u00e1n","family":"Glujovsky","sequence":"additional","affiliation":[{"name":"Reproductive Medicine; CEGYR (Centro de Estudios en Gen\u00e9tica y Reproducci\u00f3n); Buenos Aires Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea Marta","family":"Quinteiro Retamar","sequence":"additional","affiliation":[{"name":"Eggs donation program \u2013 Genetics unit; CEGYR (Centro de Estudios en Ginecologia y Reproducci\u00f3n); Buenos Aires Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cristian Roberto","family":"Alvarez Sedo","sequence":"additional","affiliation":[{"name":"Laboratory of Reproductive Biology and Genetics; CEGYR; Buenos Aires Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Agust\u00edn","family":"Ciapponi","sequence":"additional","affiliation":[{"name":"Argentine Cochrane Centre; Instituto de Efectividad Cl\u00ednica y Sanitaria (IECS-CONICET); Buenos Aires Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simone","family":"Cornelisse","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology; Radboud University Nijmegen Medical Centre; Nijmegen Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deborah","family":"Blake","sequence":"additional","affiliation":[{"name":"Repromed Fertility Specialists; Auckland New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,5,19]]},"reference":[{"issue":"11","key":"10.1002\/14651858.CD002118.pub6-BIB0001|cit1","doi-asserted-by":"crossref","first-page":"880","DOI":"10.3109\/09513590.2015.1056141","article-title":"Pregnancy outcome after blastocyst stage transfer comparing to early cleavage stage embryo transfer","volume":"31","author":"Aziminekoo","year":"2015","journal-title":"Gynecological Endocrinology"},{"key":"10.1002\/14651858.CD002118.pub6-BIB0002|cit2","first-page":"i60","article-title":"Cumulative pregnancy rates after single cleavage-stage versus blastocyst-stage embryo transfer: a randomized and prospective study","volume":"25","author":"Brugnon","year":"2010","journal-title":"Human Reproduction"},{"issue":"1","key":"10.1002\/14651858.CD002118.pub6-BIB0003|cit3","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1016\/S1472-6483(10)61736-1","article-title":"Day 3 versus day 5 embryo transfer: a prospective randomized study","volume":"7","author":"Bungum","year":"2003","journal-title":"Reproductive Biomedicine Online"},{"issue":"9","key":"10.1002\/14651858.CD002118.pub6-BIB0004|cit4","doi-asserted-by":"crossref","first-page":"1947","DOI":"10.1093\/humrep\/15.9.1947","article-title":"Day 5 versus day 3 embryo transfer: a controlled randomized trial","volume":"15","author":"Coskun","year":"2000","journal-title":"Human Reproduction"},{"issue":"Supp 1","key":"10.1002\/14651858.CD002118.pub6-BIB0005|cit5","first-page":"151","article-title":"Prospective and randomized comparison between transfer on day 2 or day 5 for patients with more than four IVF attempts","volume":"15","author":"Devreker","year":"2000","journal-title":"Human Reproduction"},{"issue":"6","key":"10.1002\/14651858.CD002118.pub6-BIB0006|cit6","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1016\/j.rbmo.2011.08.011","article-title":"Blastocyst-stage versus cleavage-stage embryo transfer in women with high oestradiol concentrations: randomized controlled trial","volume":"23","author":"Elgindy","year":"2011","journal-title":"Reproductive Biomedicine Online"},{"issue":"10","key":"10.1002\/14651858.CD002118.pub6-BIB0007|cit7","doi-asserted-by":"crossref","first-page":"2145","DOI":"10.1093\/humrep\/deg394","article-title":"Similar delivery rates in a selected group of patients, for day 2 and day 5 embryos both cultured in sequential medium: a randomized study","volume":"18","author":"Emiliani","year":"2003","journal-title":"Human Reproduction"},{"issue":"2","key":"10.1002\/14651858.CD002118.pub6-BIB0008|cit8","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1007\/s10815-014-0387-9","article-title":"Ongoing and cumulative pregnancy rate after cleavage-stage versus blastocyst-stage embryo transfer using vitrification for cryopreservation: impact of age on the results","volume":"32","author":"Fernandez-Shaw","year":"2015","journal-title":"Journal of Assisted Reproduction and Genetics"},{"key":"10.1002\/14651858.CD002118.pub6-BIB0009|cit9","unstructured":"Fernandez-Shaw S Unpublished data including live birth and cumulative live birth rates [personal communication] Email to: Demi\u00e1n Glujovsky"},{"issue":"Suppl 1","key":"10.1002\/14651858.CD002118.pub6-BIB0010|cit10","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1016\/j.fertnstert.2007.07.1111","article-title":"Single embryo transfer (SET) day 3 vs day 5 based on graduated embryo score (GES) and soluble human leukocyte antigen-G (sHLA-G): preliminary results of a prospective, randomized controlled trial","volume":"88","author":"Fisch","year":"2007","journal-title":"Fertility and Sterility"},{"issue":"1","key":"10.1002\/14651858.CD002118.pub6-BIB0011|cit11","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1016\/S0015-0282(02)04558-2","article-title":"Blastocyst transfer decreases multiple pregnancy rates in in vitro fertilization cycles: a randomized controlled trial","volume":"79","author":"Frattarelli","year":"2003","journal-title":"Fertility and Sterility"},{"issue":"Suppl 1","key":"10.1002\/14651858.CD002118.pub6-BIB0012|cit12","first-page":"i217, abstract","article-title":"Blastocyst versus day 2-3 transfer in ICSI cycles for male factor infertility: a multicenter randomized controlled trial","volume":"30","author":"Gaafar","year":"2015","journal-title":"Human Reproduction"},{"issue":"12","key":"10.1002\/14651858.CD002118.pub6-BIB0013|cit13","doi-asserted-by":"crossref","first-page":"3434","DOI":"10.1093\/humrep\/13.12.3434","article-title":"A prospective randomized trial of blastocyst culture and transfer in in-vitro fertilization","volume":"13","author":"Gardner","year":"1998","journal-title":"Human Reproduction"},{"issue":"2","key":"10.1002\/14651858.CD002118.pub6-BIB0014|cit14","doi-asserted-by":"crossref","first-page":"82","DOI":"10.4274\/tjod.99076","article-title":"Day 3 embryo transfer versus day 5 blastocyst transfers: a prospective randomized controlled trial","volume":"14","author":"Hatirnaz","year":"2017","journal-title":"Turkish Journal of Obstetrics and Gynecology"},{"key":"10.1002\/14651858.CD002118.pub6-BIB0015|cit15","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1016\/j.ejogrb.2004.06.011","article-title":"Embryo transfer is equally effective at cleavage stage and blastocyst stage: a randomized prospective study","volume":"117","author":"Hreinsson","year":"2004","journal-title":"European Journal of Obstetrics, Gynecology and Reproductive Biology"},{"issue":"1","key":"10.1002\/14651858.CD002118.pub6-BIB0016|cit16","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1016\/S0015-0282(01)02939-9","article-title":"Blastocyst culture and transfer: a step toward improved in vitro fertilization outcome","volume":"77","author":"Karaki","year":"2002","journal-title":"Fertility and Sterility"},{"issue":"8","key":"10.1002\/14651858.CD002118.pub6-BIB0017|cit17","doi-asserted-by":"crossref","first-page":"1598","DOI":"10.1093\/humrep\/dex231","article-title":"A pilot randomized controlled trial of Day 3 single embryo transfer with adjunctive time-lapse selection versus Day 5 single embryo transfer with or without adjunctive time-lapse selection","volume":"32","author":"Kaser","year":"2017","journal-title":"Human Reproduction"},{"issue":"3 (suppl 1)","key":"10.1002\/14651858.CD002118.pub6-BIB0018|cit18","doi-asserted-by":"crossref","first-page":"e312","DOI":"10.1016\/j.fertnstert.2016.07.886","article-title":"Eeva\u2122 pregnancy pilot study: a randomized controlled trial of single embryo transfer (SET) on day 3 or day 5 with or without time-lapse imaging (TLI) selection","volume":"106","author":"Kaser","year":"2016","journal-title":"Fertility and Sterility"},{"issue":"3","key":"10.1002\/14651858.CD002118.pub6-BIB0019|cit19","doi-asserted-by":"crossref","first-page":"194","DOI":"10.4103\/0974-1208.142481","article-title":"A comparative study between cleavage stage embryo transfer at day 3 and blastocyst stage transfer at day 5 in in-vitro fertilization\/intra-cytoplasmic sperm injection on clinical pregnancy rates","volume":"7","author":"Kaur","year":"2014","journal-title":"Journal of Human Reproductive Sciences"},{"issue":"4","key":"10.1002\/14651858.CD002118.pub6-BIB0020|cit20","first-page":"185","article-title":"Implantation rates after two and five days of embryo culture: a comparative study","volume":"15","author":"Kaur","year":"2013","journal-title":"JK Science"},{"key":"10.1002\/14651858.CD002118.pub6-BIB0021|cit21","doi-asserted-by":"crossref","first-page":"2550","DOI":"10.1093\/humrep\/deh447","article-title":"Should we advise patients undergoing in-vitro fertilization to start a cycle leading to a day 3 or day 5 transfer?","volume":"19","author":"Kolibianakis","year":"2004","journal-title":"Human Reproduction"},{"issue":"3","key":"10.1002\/14651858.CD002118.pub6-BIB0022|cit22","first-page":"457","article-title":"No advantage of fresh blastocyst versus cleavage stage embryo transfer in women under the age of 39: a randomized controlled study","volume":"35","author":"Levi-Setti","year":"2018","journal-title":"Human Reproduction"},{"issue":"3 (suppl 1)","key":"10.1002\/14651858.CD002118.pub6-BIB0023|cit23","doi-asserted-by":"crossref","first-page":"S118","DOI":"10.1016\/S0015-0282(01)02346-9","article-title":"A prospective, randomized study comparing blastocyst stage versus 48-72 hr embryo transfer in women failed to conceive three or more in-vitro fertilization treatment cycles","volume":"76","author":"Levitas","year":"2001","journal-title":"Fertility and Sterility"},{"issue":"3","key":"10.1002\/14651858.CD002118.pub6-BIB0024|cit24","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1016\/j.fertnstert.2003.08.031","article-title":"Blastocyst-stage embryo transfer in patients who failed to conceive in three or more day 2-3 embryo transfer cycles: a prospective, randomized study","volume":"81","author":"Levitas","year":"2004","journal-title":"Fertility and Sterility"},{"key":"10.1002\/14651858.CD002118.pub6-BIB0025|cit25","doi-asserted-by":"crossref","first-page":"1300","DOI":"10.1016\/S0015-0282(02)03090-X","article-title":"A prospective randomized study comparing day 3 with blastocyst-stage embryo transfer","volume":"77","author":"Levron","year":"2002","journal-title":"Fertility and Sterility"},{"key":"10.1002\/14651858.CD002118.pub6-BIB0026|cit26","unstructured":"Livingstone M Bowman M Single blastocyst transfer: a prospective randomised trial 17th World Congress on Fertility and Sterility; 2001 Nov 25-30; Melbourne, Australia Royal (NJ) International Federation of Fertility Societies 218"},{"issue":"Suppl 1","key":"10.1002\/14651858.CD002118.pub6-BIB0027|cit27","first-page":"17","article-title":"Blastocyst vs. cleaving embryo transfer: a prospective randomized trial","volume":"70","author":"Motta","year":"1998","journal-title":"Fertility and Sterility"},{"issue":"2","key":"10.1002\/14651858.CD002118.pub6-BIB0028|cit28","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1016\/j.fertnstert.2003.07.016","article-title":"Comparison of embryo transfer on day 2, day 3, and day 6: a prospective randomized study","volume":"81","author":"Pantos","year":"2004","journal-title":"Fertility and Sterility"},{"issue":"11","key":"10.1002\/14651858.CD002118.pub6-BIB0029|cit29","doi-asserted-by":"crossref","first-page":"3198","DOI":"10.1093\/humrep\/dei217","article-title":"Live birth rate is significantly higher after blastocyst transfer than after cleavage-stage transfer when at least four embryos are available on day 3 of culture. A randomized prospective study","volume":"20","author":"Papanikolaou","year":"2005","journal-title":"Human Reproduction"},{"issue":"Suppl 1","key":"10.1002\/14651858.CD002118.pub6-BIB0030|cit30","first-page":"s51","article-title":"Ongoing pregnancy rate is significantly higher with day 5 embryo transfer than after day 3 embryo transfer, when more than three embryos are available on the third day of embryo culture","volume":"84","author":"Verheyen","year":"2005","journal-title":"Fertility and Sterility"},{"issue":"11","key":"10.1002\/14651858.CD002118.pub6-BIB0031|cit31","doi-asserted-by":"publisher","first-page":"1139","DOI":"10.1056\/NEJMoa053524","article-title":"In vitro fertilization with single blastocyst-stage versus cleavage-stage embryos","volume":"354","author":"Papanikolaou","year":"2006","journal-title":"New England Journal of Medicine"},{"issue":"suppl_1","key":"10.1002\/14651858.CD002118.pub6-BIB0032|cit32","first-page":"i144","article-title":"Single embryo transfer: comparison of cleavage stage embryo transfer with blastocyst stage embryo transfer. A randomized prospective study","volume":"20","author":"Papanikolaou","year":"2005","journal-title":"Human Reproduction"},{"key":"10.1002\/14651858.CD002118.pub6-BIB0033|cit33","doi-asserted-by":"crossref","first-page":"1852","DOI":"10.1093\/humrep\/17.7.1852","article-title":"Day 3 embryo transfer with combined evaluation at the pronuclear and cleavage stages compares favourably with day 5 blastocyst transfer","volume":"17","author":"Ubaldi","year":"2002","journal-title":"Human Reproduction"},{"issue":"Supp 1","key":"10.1002\/14651858.CD002118.pub6-BIB0034|cit34","first-page":"143","article-title":"Blastocyst stage versus day 2 embryo transfer in IVF cycles","volume":"17","author":"Schillaci","year":"2002","journal-title":"Human Reproduction"},{"key":"10.1002\/14651858.CD002118.pub6-BIB0035|cit35","first-page":"i483","article-title":"A randomised controlled trial comparing the cost-effectiveness of blastocyst (Day 5\/6) versus cleavage stage (Day 3) embryo transfers in IVF-ICSI cycles in developing countries","volume":"32 Suppl 1","author":"Singh","year":"2017","journal-title":"Human Reproduction"},{"issue":"3","key":"10.1002\/14651858.CD002118.pub6-BIB0036|cit36","doi-asserted-by":"crossref","first-page":"S289","DOI":"10.1016\/j.fertnstert.2013.07.1081","article-title":"A prospective randomised controlled study comparing the cost effectiveness of IVF-ICSI treatment: cleavage stage (day 3) embryo transfer versus extended culture (day 5\/6 blastocyst) transfer","volume":"100","author":"Singh","year":"2013","journal-title":"Fertility and Sterility"},{"issue":"Suppl 1","key":"10.1002\/14651858.CD002118.pub6-BIB0037|cit37","first-page":"i165 Abstract n","article-title":"Day 3 or day 5 embryo transfer? A randomized prospective study","volume":"26","author":"Ten","year":"2011","journal-title":"Human Reproduction"},{"issue":"6","key":"10.1002\/14651858.CD002118.pub6-BIB0038|cit38","doi-asserted-by":"crossref","first-page":"1507","DOI":"10.1093\/humrep\/17.6.1507","article-title":"A prospective randomized study: day 2 versus day 5 embryo transfer","volume":"17","author":"Van der Auwera","year":"2002","journal-title":"Human Reproduction"},{"key":"10.1002\/14651858.CD002118.pub6-BIB0039|cit39","unstructured":"Using time-lapse technology for single embryo transfer: a prospective randomized controlled study www.chictr.org.cn\/hvshowproject.aspx?id=11293"},{"issue":"5","key":"10.1002\/14651858.CD002118.pub6-BIB0040|cit40","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1093\/humrep\/dey047","article-title":"Single embryo transfer by Day 3 time-lapse selection versus Day 5 conventional morphological selection: a randomized, open-label, non-inferiority trial","volume":"33","author":"Yang","year":"2018","journal-title":"Human Reproduction"},{"key":"10.1002\/14651858.CD002118.pub6-BIB0041|cit41","first-page":"i102","article-title":"Single embryo transfer on cleavage-stage (D3) using timelapse selection versus on blastocyst(D5) using traditional morphological selection in patients with good prognosis: a prospective randomized controlled trial","volume":"32 Suppl 1","author":"Yang","year":"2017","journal-title":"Human Reproduction"},{"key":"10.1002\/14651858.CD002118.pub6-BIB0042|cit42","doi-asserted-by":"crossref","unstructured":"Bungum L Bungum M Humaiden P Blastocyst stage transfer is not better than embryo transfer on day 3: a prospective randomized study Human Reproduction 2002 17 Suppl 1 53","DOI":"10.1016\/S1472-6483(10)61736-1"},{"key":"10.1002\/14651858.CD002118.pub6-BIB0043|cit43","doi-asserted-by":"crossref","first-page":"1370","DOI":"10.1093\/humrep\/dey112","article-title":"An informed decision between cleavage-stage and blastocyst-stage transfer in IVF requires data on the transfers of frozen-thawed embryos","volume":"33","author":"Cornelisse","year":"2018","journal-title":"Human Reproduction"},{"key":"10.1002\/14651858.CD002118.pub6-BIB0044|cit44","doi-asserted-by":"crossref","first-page":"e165","DOI":"10.1016\/j.fertnstert.2016.07.487","article-title":"Day 3 embryo transfer (ET) versus pushing to day 5 in patients with few embryos","volume":"106","author":"Green","year":"2016","journal-title":"Fertility and Sterility"},{"issue":"7-8","key":"10.1002\/14651858.CD002118.pub6-BIB0045|cit45","first-page":"635","article-title":"Coculture of human embryos with monkey kidney epithelial cells: clinical data concerning transfers delayed at D3 and D5","volume":"19","author":"Guerin","year":"1991","journal-title":"Contraception, Fertilite, Sexualite"},{"key":"10.1002\/14651858.CD002118.pub6-BIB0046|cit46","doi-asserted-by":"crossref","first-page":"e38","DOI":"10.1016\/j.fertnstert.2017.07.125","article-title":"Perinatal outcomes are similar in blastocyst compared to cleavage stage frozen-thawed embryo transfers: a SARTCORS study","volume":"108","author":"Holden","year":"2017","journal-title":"Fertility and Sterility"},{"issue":"3","key":"10.1002\/14651858.CD002118.pub6-BIB0047|cit47","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1016\/S0015-0282(01)02028-3","article-title":"A randomized prospective study on blastocyst versus day 2-3 embryo transfer","volume":"Suppl 1","author":"Levron","year":"2001","journal-title":"Fertility and Sterility"},{"key":"10.1002\/14651858.CD002118.pub6-BIB0048|cit48","first-page":"i139","article-title":"Efficiency of consecutive embryos transfer on day 3 and day 5 than replacement of 2 embryos on day 3 for women over 37 years: prospective study","volume":"24","author":"Loup","year":"2009","journal-title":"Molecular Human Reproduction"},{"issue":"Suppl 1","key":"10.1002\/14651858.CD002118.pub6-BIB0049|cit49","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1093\/humrep\/7.suppl_1.101","article-title":"Coculture of embryos on Vero cells and transfer of blastocysts in humans","volume":"7","author":"Menezo","year":"1992","journal-title":"Human Reproduction"},{"key":"10.1002\/14651858.CD002118.pub6-BIB0050|cit50","doi-asserted-by":"crossref","first-page":"1598","DOI":"10.1093\/humrep\/deh288","article-title":"A prospective, randomised study: day 3 versus hatching blastocyst stage","volume":"19","author":"Utsunomiya","year":"2004","journal-title":"Human Reproduction"},{"key":"10.1002\/14651858.CD002118.pub6-BIB0051|cit51","first-page":"i80","article-title":"A prospective evaluation of the optimal time for selecting a single embryo for transfer: day 3 vs. day 5","volume":"Suppl","author":"Vanderzwalmen","year":"2006","journal-title":"Human Reproduction"},{"issue":"1","key":"10.1002\/14651858.CD002118.pub6-BIB0052|cit52","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1016\/j.fertnstert.2006.11.070","article-title":"Prospective evaluation of the optimal time for selecting a single embryo for transfer: day 3 versus day 5","volume":"88","author":"Zech","year":"2007","journal-title":"Fertility and Sterility"},{"issue":"Suppl 1","key":"10.1002\/14651858.CD002118.pub6-BIB0053|cit53","first-page":"i2","article-title":"Cleavage stage embryo transfer impairs cumulative live birth rates and time to livebirth as compared to blastocyst transfer in oocyte recipients. A randomized controlled trial","volume":"35","author":"Clua Obrado","year":"2020","journal-title":"Human Reproduction"},{"key":"10.1002\/14651858.CD002118.pub6-BIB0054|cit54","unstructured":"Cumulative live birth rates after cleavage-stage versus blastocyst-stage embryo transfer: a multicenter, prospective, randomized controlled trial www.chictr.org.cn\/showprojen.aspx?proj=10698"},{"key":"10.1002\/14651858.CD002118.pub6-BIB0055|cit55","doi-asserted-by":"crossref","first-page":"e042395","DOI":"10.1136\/bmjopen-2020-042395","article-title":"Comparing the cumulative live birth rate of cleavage-stage versus blastocyst-stage embryo transfers between IVF cycles: a study protocol for a multicentre randomised controlled superiority trial (the ToF trial)","volume":"11","author":"Cornelisse","year":"2021","journal-title":"BMJ Open"},{"key":"10.1002\/14651858.CD002118.pub6-BIB0056|cit56","unstructured":"ToF-studie Embryo transfer, day Three Or day Five, in good prognosis IVF cycles www.who.int\/trialsearch\/Trial2.aspx?TrialID=NTR7034"},{"key":"10.1002\/14651858.CD002118.pub6-BIB0057|cit57","unstructured":"Trial comparing blastocyst transfer with cleavage stage transfer in women with increased maternal age trialsearch.who.int\/?TrialID=ISRCTN48090543"},{"key":"10.1002\/14651858.CD002118.pub6-BIB0058|cit58","unstructured":"Comparison of 5 day embryo transfer with 2-3 day transfer in patients with previous in vitro fertilization failure clinicaltrials.gov\/ct2\/show\/NCT01107002"},{"key":"10.1002\/14651858.CD002118.pub6-BIB0059|cit59","unstructured":"Effects of blastocyst stage compared with cleavage stage embryo transfer in women below 39 years clinicaltrials.gov\/show\/NCT02639000"},{"key":"10.1002\/14651858.CD002118.pub6-BIB0060|cit60","unstructured":"Cleave-stage transfer on day 3 versus day 5 transfer when only one embryo available (Cleave-blast) clinicaltrials.gov\/show\/NCT04210414"},{"issue":"1","key":"10.1002\/14651858.CD002118.pub6-BIB0061|cit61","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1186\/s12978-020-0870-y","article-title":"Non-inferiority of cleavage-stage versus blastocyst-stage embryo transfer in poor prognosis IVF patients (PRECiSE trial): study protocol for a randomized controlled trial","volume":"17","author":"Neuhausser","year":"2020","journal-title":"Reproductive Health"},{"key":"10.1002\/14651858.CD002118.pub6-BIB0062|cit62","unstructured":"Blastocyst versus day 2 transfer in low responders www.who.int\/trialsearch\/Trial2.aspx?TrialID=PACTR201402000773124"},{"key":"10.1002\/14651858.CD002118.pub6-BIB0063|cit63","unstructured":"A randomized controlled trial of pregnancy outcome of sequential versus day 3 and day 5 embryo transfer in cases with recurrent implantation failure www.who.int\/trialsearch\/Trial2.aspx?TrialID=PACTR201709002592834"},{"issue":"1","key":"10.1002\/14651858.CD002118.pub6-BIB0064|cit64","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1002\/uog.18942","article-title":"Influence of cryopreservation on perinatal outcome after blastocyst- vs cleavage-stage embryo transfer: systematic review and meta-analysis","volume":"51","author":"Alviggi","year":"2018","journal-title":"Ultrasound in Obstetrics and Gynecology"},{"issue":"5","key":"10.1002\/14651858.CD002118.pub6-BIB0065|cit65","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD011320.pub4","article-title":"Time-lapse systems for embryo incubation and assessment in assisted reproduction","author":"Armstrong","year":"2019","journal-title":"Cochrane Database of Systematic Reviews"},{"issue":"1","key":"10.1002\/14651858.CD002118.pub6-BIB0066|cit66","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1093\/humrep\/dei291","article-title":"Preimplantation genetic screening reveals a high incidence of aneuploidy and mosaicism in embryos from young women undergoing IVF","volume":"21","author":"Baart","year":"2006","journal-title":"Human Reproduction"},{"key":"10.1002\/14651858.CD002118.pub6-BIB0067|cit67","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1001\/jama.1996.03540080059030","article-title":"Improving the quality of reporting of randomized controlled trials: the CONSORT statement","volume":"276","author":"Begg","year":"1996","journal-title":"JAMA"},{"issue":"6","key":"10.1002\/14651858.CD002118.pub6-BIB0068|cit68","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1023\/A:1009461213139","article-title":"Blastocyst-ET and monozygotic twinning","volume":"17","author":"Behr","year":"2000","journal-title":"Journal of Assisted Reproduction and Genetics"},{"key":"10.1002\/14651858.CD002118.pub6-BIB0069|cit69","unstructured":"Borg K Moller A Hammar M Blake D Hillensjo T Wikland M Blastocyst culture - more or less stressful for patients? European Society of Human Reproduction and Enbryology (ESHRE) Bologna 2000 48"},{"key":"10.1002\/14651858.CD002118.pub6-BIB0070|cit70","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1038\/332459a0","article-title":"Human gene expression first occurs between the four and eight-cell stages of preimplantation development","volume":"332","author":"Braude","year":"1988","journal-title":"Nature"},{"issue":"2","key":"10.1002\/14651858.CD002118.pub6-BIB0071|cit71","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1016\/j.fertnstert.2018.10.025","article-title":"Risk factors for monozygotic twinning after in vitro fertilization: a systematic review and meta-analysis","volume":"111","author":"Busnelli","year":"2019","journal-title":"Fertility and Sterility"},{"key":"10.1002\/14651858.CD002118.pub6-BIB0072|cit72","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1093\/oxfordjournals.humrep.a137044","article-title":"Impairment of hatching process following IVF in the human and improvement of implantation by assisted hatching using micromanipulation","volume":"5","author":"Cohen","year":"1990","journal-title":"Human Reproduction"},{"issue":"7","key":"10.1002\/14651858.CD002118.pub6-BIB0073|cit73","doi-asserted-by":"crossref","first-page":"1370","DOI":"10.1093\/humrep\/dey112","article-title":"An informed decision between cleavage-stage and blastocyst-stage transfer in IVF requires data on the transfers of frozen\u2013thawed embryos","volume":"33","author":"Cornelisse","year":"2018","journal-title":"Human Reproduction"},{"issue":"5","key":"10.1002\/14651858.CD002118.pub6-BIB0074|cit74","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1016\/0002-9378(72)90792-2","article-title":"A simple non-surgical technique to obtain unimplanted eggs from human uteri","volume":"112","author":"Croxatto","year":"1972","journal-title":"American Journal of Obstetrics and Gynecology"},{"key":"10.1002\/14651858.CD002118.pub6-BIB0075|cit75","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1002\/mrd.1120060203","article-title":"Spontaneous hardening of the zona pellucida of mouse oocytes during in vitro culture","volume":"6","author":"De Felici","year":"1982","journal-title":"Gamete Research"},{"issue":"9","key":"10.1002\/14651858.CD002118.pub6-BIB0076|cit76","doi-asserted-by":"crossref","first-page":"2402","DOI":"10.1093\/humrep\/17.9.2402","article-title":"High outcome predictability after IVF using a combined score for zygote and embryo morphology and growth rate","volume":"17","author":"De Placido","year":"2002","journal-title":"Human Reproduction"},{"issue":"5","key":"10.1002\/14651858.CD002118.pub6-BIB0077|cit77","doi-asserted-by":"crossref","first-page":"536","DOI":"10.1093\/humupd\/dms016","article-title":"A critical appraisal of cryopreservation (slow cooling versus vitrification) of human oocytes and embryos","volume":"18","author":"Edgar","year":"2012","journal-title":"Human Reproduction Update"},{"key":"10.1002\/14651858.CD002118.pub6-BIB0078|cit78","first-page":"17","volume-title":"Principles and Practice of Assisted Human Reproduction","author":"Edwards","year":"1995"},{"key":"10.1002\/14651858.CD002118.pub6-BIB0079|cit79","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1111\/j.1749-6632.2001.tb03802.x","article-title":"Assessing uterine receptivity in 2001: Ultrasonographic glances at the new millennium","volume":"943","author":"Fanchin","journal-title":"Annals of the New York Academy of Sciences"},{"issue":"2","key":"10.1002\/14651858.CD002118.pub6-BIB0080|cit80","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1016\/S0015-0282(16)58097-2","article-title":"Environment of the preimplantation human embryo in vivo: metabolite analysis of oviduct and uterine fluids and metabolism of cumulus cell","volume":"65","author":"Gardner","year":"1996","journal-title":"Fertility and Sterility"},{"issue":"1","key":"10.1002\/14651858.CD002118.pub6-BIB0081|cit81","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/S0015-0282(97)00438-X","article-title":"Culture and transfer of human blastocysts increases implantation rates and reduces the need for multiple embryo transfers","volume":"69","author":"Gardner","year":"1998","journal-title":"Fertility and Sterility"},{"key":"10.1002\/14651858.CD002118.pub6-BIB0082|cit82","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1016\/S0015-0282(02)04576-4","article-title":"Changing the start temperature and cooling rate in a slow-freezing protocol increases human blastocyst viability","volume":"79","author":"Gardner","year":"2003","journal-title":"Fertility and Sterility"},{"key":"10.1002\/14651858.CD002118.pub6-BIB0083|cit83","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1016\/j.fertnstert.2003.07.023","article-title":"Single blastocyst transfer a prospective randomised trial","volume":"81","author":"Gardner","year":"2004","journal-title":"Fertility and Sterility"},{"issue":"11","key":"10.1002\/14651858.CD002118.pub6-BIB0084|cit84","first-page":"2282","article-title":"Perinatal and maternal outcome after vitrification of blastocysts: a Nordic study in singletons from the CoNARTaS group","volume":"34","author":"Ginstr\u00f6m","year":"2019","journal-title":"Human Reproduction"},{"key":"10.1002\/14651858.CD002118.pub6-BIB0085|cit85","unstructured":"GRADEpro GDT McMaster University (developed by Evidence Prime) 2015"},{"issue":"2","key":"10.1002\/14651858.CD002118.pub6-BIB0086|cit86","first-page":"249","article-title":"Beware of the implantation rate","volume":"31","author":"Greisinger","year":"2016","journal-title":"Human Reproducton"},{"key":"10.1002\/14651858.CD002118.pub6-BIB0087|cit87","first-page":"15","article-title":"Avoidance of multiple pregnancy by use of single embryo transfer","volume":"57","author":"Hamberger","year":"2005","journal-title":"Minerva Ginecologica"},{"key":"10.1002\/14651858.CD002118.pub6-BIB0088|cit88","doi-asserted-by":"crossref","unstructured":"Higgins JP Green S Cochrane Handbook for Systematic Reviews of Interventions version 6.0 (updated July 2019). Cochrane, 2019 Available from www.training.cochrane.org\/handbook","DOI":"10.1002\/9781119536604"},{"key":"10.1002\/14651858.CD002118.pub6-BIB0089|cit89","doi-asserted-by":"crossref","unstructured":"Higgins JP Savovi\u0107 J Page MJ Elbers RG Sterne JA Chapter 8: Assessing risk of bias in a randomized trial. In: Higgins JP, Thomas J, Chandler J, Cumpston M, Li T, Page MJ, et al (editors). Cochrane Handbook for Systematic Reviews of Interventions version 6.0 (updated July 2019). Cochrane, 2019 Available from www.training.cochrane.org\/handbook","DOI":"10.1002\/9781119536604.ch8"},{"issue":"4","key":"10.1002\/14651858.CD002118.pub6-BIB0090|cit90","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1007\/s10815-010-9522-4","article-title":"In vitro and in vivo viability of human blastocysts collapsed by laser pulse or osmotic shock prior to vitrification","volume":"28","author":"Iwayama","year":"2011","journal-title":"Journal of Assisted Reproduction and Genetics"},{"issue":"4","key":"10.1002\/14651858.CD002118.pub6-BIB0091|cit91","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1023\/B:JARG.0000029493.54929.be","article-title":"Monozygotic twins and triplets in association with blastocyst transfer","volume":"21","author":"Jain","year":"2004","journal-title":"Journal of Assisted Reproduction and Genetics"},{"issue":"6","key":"10.1002\/14651858.CD002118.pub6-BIB0092|cit92","doi-asserted-by":"crossref","first-page":"1405","DOI":"10.1093\/humrep\/14.6.1405","article-title":"The benefits of extended culture","volume":"14","author":"Jones","year":"1999","journal-title":"Human Reproduction"},{"issue":"8","key":"10.1002\/14651858.CD002118.pub6-BIB0093|cit93","doi-asserted-by":"crossref","first-page":"1748","DOI":"10.1093\/humrep\/den123","article-title":"Novel strategy with potential to identify developmentally competent IVF blastocysts","volume":"23","author":"Jones","year":"2008","journal-title":"Human Reproduction"},{"issue":"8","key":"10.1002\/14651858.CD002118.pub6-BIB0094|cit94","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD003416.pub5","article-title":"Number of embryos for transfer following in vitro fertilisation or intra-cytoplasmic sperm injection","author":"Kamath","year":"2020","journal-title":"Cochrane Database of Systematic Reviews"},{"issue":"3","key":"10.1002\/14651858.CD002118.pub6-BIB0095|cit95","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1093\/humrep\/16.3.476","article-title":"A prospective, randomized study comparing day 2 and day 3 embryo transfer in human IVF","volume":"16","author":"Laverge","year":"2001","journal-title":"Human Reproduction"},{"key":"10.1002\/14651858.CD002118.pub6-BIB0096|cit96","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1016\/j.fertnstert.2006.06.058","article-title":"Blastocyst embryo transfer is associated with a sex-ratio imbalance in favor of male offspring","volume":"87","author":"Luna","year":"2007","journal-title":"Fertility and Sterility"},{"issue":"5","key":"10.1002\/14651858.CD002118.pub6-BIB0097|cit97","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1023\/A:1022596528036","article-title":"Incidence of chromosomal abnormalities from a morphologically normal cohort of embryos in poor-prognosis patients","volume":"15","author":"Magli","year":"1998","journal-title":"Journal of Assisted Reproduction and Genetics"},{"key":"10.1002\/14651858.CD002118.pub6-BIB0098|cit98","doi-asserted-by":"crossref","first-page":"1781","DOI":"10.1093\/humrep\/15.8.1781","article-title":"Chromosome mosaicism in day 3 aneuploid embryos that develop to morphologically normal blastocysts in vitro","volume":"15","author":"Magli","year":"2000","journal-title":"Human Reproduction"},{"issue":"2","key":"10.1002\/14651858.CD002118.pub6-BIB0099|cit99","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1016\/j.rbmo.2015.09.016","article-title":"Should we be promoting embryo transfer at blastocyst stage?","volume":"32","author":"Maheshwari","year":"2016","journal-title":"Reproductive BioMedicine Online"},{"issue":"6","key":"10.1002\/14651858.CD002118.pub6-BIB0100|cit100","doi-asserted-by":"crossref","first-page":"1035","DOI":"10.1016\/S0015-0282(99)00409-4","article-title":"Introduction of blastocyst culture and transfer for all patients in an in vitro fertilization program","volume":"72","author":"Marek","year":"1999","journal-title":"Fertility and Sterility"},{"key":"10.1002\/14651858.CD002118.pub6-BIB0101|cit101","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1530\/jrf.0.0490175","article-title":"Successful autotransfer of tubal eggs in the rhesus monkey (Macaca mulatta)","volume":"49","author":"Marston","year":"1977","journal-title":"Journal of Reproduction and Fertility"},{"issue":"11","key":"10.1002\/14651858.CD002118.pub6-BIB0102|cit102","doi-asserted-by":"crossref","first-page":"2561","DOI":"10.1093\/humrep\/dew244","article-title":"Obstetrical and perinatal outcomes following blastocyst transfer compared to cleavage transfer: a systematic review and meta-analysis","volume":"31","author":"Martins","year":"2016","journal-title":"Human Reproduction"},{"issue":"5","key":"10.1002\/14651858.CD002118.pub6-BIB0103|cit103","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1002\/uog.17327","article-title":"Blastocyst vs cleavage-stage embryo transfer: systematic review and meta-analysis of reproductive outcomes","volume":"49","author":"Martins","year":"2017","journal-title":"Ultrasound in Obstetrics & Gynecology"},{"issue":"2","key":"10.1002\/14651858.CD002118.pub6-BIB0104|cit104","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1095\/biolreprod42.2.301","article-title":"Improvement of human embryo development in vitro by coculture on monolayers of Vero cells","volume":"42","author":"Menezo","year":"1990","journal-title":"Biology of Reproduction"},{"issue":"2","key":"10.1002\/14651858.CD002118.pub6-BIB0105|cit105","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/S0015-0282(99)00256-3","article-title":"Birth weight and sex ratio after transfer at the blastocyst stage in humans","volume":"72","author":"Menezo","year":"1999","journal-title":"Fertility and Sterility"},{"issue":"2","key":"10.1002\/14651858.CD002118.pub6-BIB0106|cit106","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/S0015-0282(99)00262-9","article-title":"Two-blastocyst transfer has similar pregnancy rates and a decreased multiple gestation rate compared with three-blastocyst transfer","volume":"72","author":"Milki","year":"1999","journal-title":"Fertility and Sterility"},{"key":"10.1002\/14651858.CD002118.pub6-BIB0107|cit107","doi-asserted-by":"crossref","first-page":"1697","DOI":"10.1016\/j.fertnstert.2003.10.050","article-title":"Elective single blastoyst transfer","volume":"81","author":"Milki","year":"2004","journal-title":"Fertility and Sterility"},{"issue":"5","key":"10.1002\/14651858.CD002118.pub6-BIB0108|cit108","doi-asserted-by":"crossref","first-page":"1028","DOI":"10.1016\/j.fertnstert.2006.09.013","article-title":"Risk of monozygotic twinning with blastocyst transfer decreases over time: an 8 year experience","volume":"87","author":"Moayeri","year":"2007","journal-title":"Fertility and Sterility"},{"issue":"3","key":"10.1002\/14651858.CD002118.pub6-BIB0109|cit109","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/S1472-6483(10)61810-X","article-title":"Chromosome mosaicism in cleavage-stage human embryos: evidence of a maternal age effect","volume":"4","author":"Munne","year":"2002","journal-title":"Reproductive Biomedicine Online"},{"issue":"3","key":"10.1002\/14651858.CD002118.pub6-BIB0110|cit110","doi-asserted-by":"crossref","first-page":"S257","DOI":"10.1016\/j.placenta.2011.05.011","article-title":"A review of the promises and pitfalls of oocyte and embryo metabolomics","volume":"32","author":"Nel-Themaat","year":"2011","journal-title":"Placenta"},{"issue":"2","key":"10.1002\/14651858.CD002118.pub6-BIB0111|cit111","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1007\/BF02766828","article-title":"Zona pellucida thickness variation and occurrence of visible mononucleated blastomeres in preembryos are associated with a high pregnancy rate in IVF treatments","volume":"15","author":"Palmstierna","year":"1998","journal-title":"Journal of Assisted Reproduction and Genetics"},{"issue":"1","key":"10.1002\/14651858.CD002118.pub6-BIB0112|cit112","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1093\/humrep\/dem339","article-title":"Live birth rates after transfer of equal number of blastocysts or cleavage-stage embryos in IVF. A systematic review and meta-analysis","volume":"23","author":"Papanikolaou","year":"2008","journal-title":"Human Reproduction"},{"issue":"Suppl_3","key":"10.1002\/14651858.CD002118.pub6-BIB0113|cit113","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1093\/humrep\/14.Suppl_3.215-b","article-title":"P-150. A prospective semi-randomized study of blastocyst transfer in an IVF programme","volume":"14","author":"Plachot","year":"1999","journal-title":"Human Reproduction"},{"issue":"8","key":"10.1002\/14651858.CD002118.pub6-BIB0114|cit114","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1093\/oxfordjournals.humrep.a136618","article-title":"Embryo scoring as a prognostic tool in IVF treatment","volume":"2","author":"Puissant","year":"1987","journal-title":"Human Reproduction"},{"key":"10.1002\/14651858.CD002118.pub6-BIB0115|cit115","unstructured":"Review Manager Web (RevMan Web) Nordic Cochrane Centre, The Cochrane Collaboration 2020"},{"issue":"5","key":"10.1002\/14651858.CD002118.pub6-BIB0116|cit116","doi-asserted-by":"crossref","first-page":"1190","DOI":"10.1016\/j.fertnstert.2015.01.045","article-title":"Freeze-all policy: fresh vs. frozen-thawed embryo policy","volume":"103","author":"Roque","year":"2015","journal-title":"Fertility and Sterility"},{"issue":"11","key":"10.1002\/14651858.CD002118.pub6-BIB0117|cit117","doi-asserted-by":"crossref","first-page":"3035","DOI":"10.1093\/oxfordjournals.humrep.a135842","article-title":"The probability of pregnancy after embryo transfer is affected by the age of the patient, cause of infertility, number of embryos transferred and the average morphology score, as revealed by multiple logistic regression analysis","volume":"10","author":"Roseboom","year":"1995","journal-title":"Human Reproduction"},{"issue":"6","key":"10.1002\/14651858.CD002118.pub6-BIB0118|cit118","doi-asserted-by":"crossref","first-page":"1245","DOI":"10.1016\/S0015-0282(16)58349-6","article-title":"A prospective, randomized study of embryo transfer results after 3 or 5 days of embryo culture in in vitro fertilization","volume":"65","author":"Scholtes","year":"1996","journal-title":"Fertility and Sterility"},{"key":"10.1002\/14651858.CD002118.pub6-BIB0119|cit119","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1055\/s-2001-18045","article-title":"Blastocyst versus day 2 or 3 transfer","volume":"19","author":"Schoolcraft","year":"2001","journal-title":"Seminars in Reproductive Medicine"},{"issue":"11","key":"10.1002\/14651858.CD002118.pub6-BIB0120|cit120","doi-asserted-by":"crossref","first-page":"2394","DOI":"10.1093\/humrep\/15.11.2394","article-title":"The morphology of human pronuclear embryos is positively related to blastocyst development and implantation","volume":"15","author":"Scott","year":"2000","journal-title":"Human Reproduction"},{"key":"10.1002\/14651858.CD002118.pub6-BIB0121|cit121","first-page":"66","volume-title":"Manual of Embryo Culture in Human Assisted Reproduction","year":"2021"},{"key":"10.1002\/14651858.CD002118.pub6-BIB0122|cit122","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1375\/twin.3.4.217","article-title":"Assisted reproductive technologies and monozygous twins: implications for future study and clinical practice","volume":"2","author":"Sills","year":"2000","journal-title":"Twin Research"},{"key":"10.1002\/14651858.CD002118.pub6-BIB0123|cit123","doi-asserted-by":"crossref","first-page":"848","DOI":"10.1016\/j.fertnstert.2006.03.040","article-title":"Prediction of embryo developmental potential and pregnancy based on early stage morphological characteristics","volume":"86","author":"Sjoblom","year":"2006","journal-title":"Fertility and Sterility"},{"issue":"4","key":"10.1002\/14651858.CD002118.pub6-BIB0124|cit124","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1093\/humrep\/deaa032","article-title":"Obstetric and perinatal risks in 4601 singletons and 884 twins conceived after fresh blastocyst transfers: a Nordic study from the CoNARTaS group","volume":"35","author":"Spangmose","year":"2020","journal-title":"Human Reproduction"},{"issue":"12","key":"10.1002\/14651858.CD002118.pub6-BIB0125|cit125","doi-asserted-by":"crossref","first-page":"2849","DOI":"10.1093\/humrep\/deh536","article-title":"Comparison of blastocyst transfer with or without preimplantation genetic diagnosis for aneuploidy screening in couples with advanced maternal age: a prospective randomised control trial","volume":"19","author":"Staessen","year":"2004","journal-title":"Human Reproduction"},{"issue":"1","key":"10.1002\/14651858.CD002118.pub6-BIB0126|cit126","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1093\/oxfordjournals.humrep.a137542","article-title":"The cumulative embryo score: a predictive embryo scoring technique to select the optimal number of embryos to transfer in an in-vitro fertilization and embryo transfer programme","volume":"7","author":"Steer","year":"1992","journal-title":"Human Reproduction"},{"key":"10.1002\/14651858.CD002118.pub6-BIB0127|cit127","doi-asserted-by":"crossref","first-page":"l4898","DOI":"10.1136\/bmj.l4898","article-title":"RoB 2: a revised tool for assessing risk of bias in randomised trials","volume":"366","author":"Sterne","year":"2019","journal-title":"BMJ"},{"key":"10.1002\/14651858.CD002118.pub6-BIB0128|cit128","doi-asserted-by":"crossref","unstructured":"Time to take human embryo culture seriously\u2020 Hum Reprod 31 10 2174 2182","DOI":"10.1093\/humrep\/dew157"},{"key":"10.1002\/14651858.CD002118.pub6-BIB0129|cit129","first-page":"42","volume-title":"Manual of Embryo Culture in Human Assisted Reproduction","author":"Sturmey Roger","year":"2021"},{"issue":"12","key":"10.1002\/14651858.CD002118.pub6-BIB0130|cit130","doi-asserted-by":"crossref","first-page":"3285","DOI":"10.1093\/humrep\/13.12.3285","article-title":"Blastocyst stage transfer: pitfalls and benefits. Too soon to abandon practice?","volume":"13","author":"Tsirgotis","year":"1998","journal-title":"Human Reproduction"},{"key":"10.1002\/14651858.CD002118.pub6-BIB0131|cit131","doi-asserted-by":"crossref","first-page":"1000","DOI":"10.1093\/humrep\/deg133","article-title":"Common statistical errors in the design and analysis of subfertility trials","volume":"18","author":"Vail","year":"2003","journal-title":"Human Reproduction"},{"issue":"5","key":"10.1002\/14651858.CD002118.pub6-BIB0132|cit132","doi-asserted-by":"crossref","first-page":"962","DOI":"10.1016\/S0015-0282(01)02018-0","article-title":"Increasing levels of estradiol are deleterious to embryonic implantation because they affect the embryo","volume":"76","author":"Valbuena","year":"2001","journal-title":"Fertility and Sterility"},{"key":"10.1002\/14651858.CD002118.pub6-BIB0133|cit133","doi-asserted-by":"crossref","first-page":"1525","DOI":"10.1093\/oxfordjournals.humrep.a138293","article-title":"Development of human embryos to the hatched blastocyst stage in the presence or absence of a monolayer of Vero cells","volume":"8","author":"Van Blerkom","year":"1993","journal-title":"Human Reproduction"},{"issue":"1","key":"10.1002\/14651858.CD002118.pub6-BIB0134|cit134","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1093\/humupd\/dmn045","article-title":"The risk of monozygotic twins after assisted reproductive technology: a systematic review and meta-analysis","volume":"15","author":"Vitthala","journal-title":"Hum Reprod Update"},{"issue":"3","key":"10.1002\/14651858.CD002118.pub6-BIB0135|cit135","doi-asserted-by":"crossref","first-page":"815","DOI":"10.3349\/ymj.2014.55.3.815","article-title":"Blastocyst transfer ameliorates live birth rate compared with cleavage-stage embryos transfer in fresh in vitro fertilization or intracytoplasmic sperm injection cycles: reviews and meta-analysis","volume":"55","author":"Wang","year":"2014","journal-title":"Yonsei Medical Journal"},{"key":"10.1002\/14651858.CD002118.pub6-BIB0136|cit136","unstructured":"Dean JH Sullivan EA Assisted reproduction technology in Australia and New Zealand 2003; February 2006 Available at www.aihw.gov.au\/getmedia\/1945b5f3-0566-4f60-8035-761ca876eeb8\/artanz03.pdf.aspx?inline=true"},{"key":"10.1002\/14651858.CD002118.pub6-BIB0137|cit137","unstructured":"World Health Organization (WHO) Infertility - Key facts www.who.int\/news-room\/fact-sheets\/detail\/infertility"},{"key":"10.1002\/14651858.CD002118.pub6-BIB0138|cit138","unstructured":"World Health Organization (WHO) Infertility www.who.int\/health-topics\/infertility#tab=tab_1"},{"issue":"8","key":"10.1002\/14651858.CD002118.pub6-BIB0139|cit139","doi-asserted-by":"publisher","first-page":"1685","DOI":"10.1093\/humrep\/dew127","article-title":"Pregnancy and birth outcomes following fresh or vitrified embryo transfer according to blastocyst morphology and expansion stage, and culturing strategy for delayed development","volume":"31","author":"Wirleitner","year":"2016","journal-title":"Human Reproduction"},{"key":"10.1002\/14651858.CD002118.pub6-BIB0140|cit140","doi-asserted-by":"crossref","first-page":"1144","DOI":"10.1093\/oxfordjournals.humrep.a137810","article-title":"Improved development of human embryos in vitro by a human oviductal cell co-culture system","volume":"7","author":"Yeung","year":"1992","journal-title":"Human Reproduction"},{"issue":"2","key":"10.1002\/14651858.CD002118.pub6-BIB0141|cit141","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD011184.pub3","article-title":"Fresh versus frozen embryo transfers in assisted reproduction","author":"Zaat","journal-title":"Cochrane Database of Systematic Reviews"},{"issue":"2","key":"10.1002\/14651858.CD002118.pub6-BIB0142|cit142","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD002118","article-title":"Cleavage stage versus blastocyst stage embryo transfer in assisted conception (In vitro fertilisation, Intracytoplasmic sperm injection)","author":"Blake","year":"2000","journal-title":"Cochrane Database of Systematic Reviews"},{"issue":"2","key":"10.1002\/14651858.CD002118.pub6-BIB0143|cit143","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD002118","article-title":"Cleavage stage versus blastocyst stage embryo transfer in assisted conception","author":"Blake","year":"2002","journal-title":"Cochrane Database of Systematic Reviews"},{"issue":"4","key":"10.1002\/14651858.CD002118.pub6-BIB0144|cit144","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD002118.pub2","article-title":"Cleavage stage versus blastocyst stage embryo transfer in assisted conception","author":"Blake","year":"2005","journal-title":"Cochrane Database of Systematic Reviews"},{"issue":"4","key":"10.1002\/14651858.CD002118.pub6-BIB0145|cit145","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD002118.pub3","article-title":"Cleavage stage versus blastocyst stage embryo transfer in assisted conception","author":"Blake","year":"2007","journal-title":"Cochrane Database of Systematic Reviews"},{"issue":"7","key":"10.1002\/14651858.CD002118.pub6-BIB0146|cit146","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD002118.pub4","article-title":"Cleavage stage versus blastocyst stage embryo transfer in assisted reproductive technology","author":"Glujovsky","year":"2012","journal-title":"Cochrane Database of Systematic Reviews"}],"updated-by":[{"DOI":"10.1002\/14651858.cd002118.pub7","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2026,1,23]],"date-time":"2026-01-23T00:00:00Z","timestamp":1769126400000}}],"container-title":["Cochrane Database of Systematic Reviews"],"original-title":[],"language":"en","deposited":{"date-parts":[[2024,1,2]],"date-time":"2024-01-02T16:30:53Z","timestamp":1704213053000},"score":1,"resource":{"primary":{"URL":"http:\/\/doi.wiley.com\/10.1002\/14651858.CD002118.pub6"}},"subtitle":[],"editor":[{"name":"Cochrane Gynaecology and Fertility Group","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2022,5,19]]},"references-count":146,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2022,6]]}},"URL":"https:\/\/doi.org\/10.1002\/14651858.cd002118.pub6","relation":{},"ISSN":["1465-1858"],"issn-type":[{"value":"1465-1858","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,5,19]]}}}