{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,30]],"date-time":"2025-12-30T22:55:37Z","timestamp":1767135337811,"version":"build-2238731810"},"update-to":[{"DOI":"10.1002\/14651858.cd002217","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2013,1,31]],"date-time":"2013-01-31T00:00:00Z","timestamp":1359590400000}}],"reference-count":28,"publisher":"Wiley","content-domain":{"domain":["wiley.com","cochranelibrary.com"],"crossmark-restriction":true},"short-container-title":[],"DOI":"10.1002\/14651858.cd002217.pub2","type":"journal-article","created":{"date-parts":[[2013,1,29]],"date-time":"2013-01-29T08:15:03Z","timestamp":1359447303000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Phenobarbitone versus phenytoin monotherapy for partial onset seizures and generalised onset tonic-clonic seizures"],"prefix":"10.1002","author":[{"given":"Sarah J","family":"Nolan","sequence":"first","affiliation":[{"name":"University of Liverpool; Department of Biostatistics; Shelley's Cottage Brownlow Street Liverpool UK L69 3GS"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Catrin","family":"Tudur Smith","sequence":"additional","affiliation":[{"name":"University of Liverpool; Department of Biostatistics; Shelley's Cottage Brownlow Street Liverpool UK L69 3GS"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jennifer","family":"Pulman","sequence":"additional","affiliation":[{"name":"Institute of Translational Medicine, University of Liverpool; Department of Molecular and Clinical Pharmacology; Clinical Sciences Centre for Research and Education, Lower Lane Fazakerley Liverpool Merseyside UK L9 7LJ"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anthony G","family":"Marson","sequence":"additional","affiliation":[{"name":"Institute of Translational Medicine, University of Liverpool; Department of Molecular and Clinical Pharmacology; Clinical Sciences Centre for Research and Education, Lower Lane Fazakerley Liverpool Merseyside UK L9 7LJ"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,1,31]]},"reference":[{"issue":"5","key":"10.1002\/14651858.CD002217.pub2-BIB0001|cit1","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1212\/WNL.24.5.401","article-title":"Carbamazepine for epilepsy: a controlled prospective evaluation","volume":"24","author":"Cereghino","year":"1974","journal-title":"Neurology"},{"key":"10.1002\/14651858.CD002217.pub2-BIB0002|cit2","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1016\/S0022-510X(97)85646-8","article-title":"Randomised 36-month comparative study of valproic acid (VPA), phenytoin (PHT), phenobarbital (PHB) and carbamazepine (CBZ) efficacy in patients with newly diagnosed epilepsy with partial complex seizures","volume":"150","author":"Czapinski","year":"1997","journal-title":"Journal of the Neurological Sciences"},{"key":"10.1002\/14651858.CD002217.pub2-BIB0003|cit3","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1016\/S0140-6736(96)90074-4","article-title":"Randomised comparative monotherapy trial of phenobarbitone, phenytoin, carbamazepine, or sodium valproate for newly diagnosed childhood epilepsy","volume":"347","author":"Silva","year":"1996","journal-title":"Lancet"},{"issue":"1","key":"10.1002\/14651858.CD002217.pub2-BIB0004|cit4","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1002\/cpt19623123","article-title":"Comparison of the effectiveness of phenobarbital, mephobarbital, primidone, diphenylhydantoin, ethotoin, metharbital and methylphenylhydantoin in motor seizures","volume":"3","author":"Gruber","year":"1962","journal-title":"Clinical Pharmacology and Therapeutics"},{"issue":"1","key":"10.1002\/14651858.CD002217.pub2-BIB0005|cit5","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1136\/jnnp.58.1.44","article-title":"Phenobarbitone, phenytoin, carbamazepine, or sodium valproate for newly diagnosed adult epilepsy: a randomised comparative monotherapy trial","volume":"58","author":"Heller","year":"1995","journal-title":"Journal of Neurology, Neurosurgery, and Psychiatry"},{"issue":"3","key":"10.1002\/14651858.CD002217.pub2-BIB0006|cit6","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1056\/NEJM198507183130303","article-title":"Comparison of carbamazepine, phenobarbital, phenytoin, and primidone in partial and secondarily generalized tonic-clonic seizures","volume":"313","author":"Mattson","year":"1985","journal-title":"New England Journal of Medicine"},{"key":"10.1002\/14651858.CD002217.pub2-BIB0007|cit7","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/S0140-6736(97)06250-8","article-title":"Randomised controlled trial to assess acceptability of phenobarbital for childhood epilepsy in rural India","volume":"351","author":"Pal","year":"1998","journal-title":"Lancet"},{"issue":"7","key":"10.1002\/14651858.CD002217.pub2-BIB0008|cit8","first-page":"549","article-title":"Comparison of phenobarbitone, phenytoin with sodium valproate: randomised, double-blind study","volume":"33","author":"Thilothammal","year":"1996","journal-title":"Indian Pediatrics"},{"key":"10.1002\/14651858.CD002217.pub2-BIB0009|cit9","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1192\/bjp.112.488.737","article-title":"Tegretol (carbamazepine): a controlled trial of a new anti-convulsant","volume":"112","author":"Bird","year":"1966","journal-title":"British Journal of Psychiatry"},{"issue":"6","key":"10.1002\/14651858.CD002217.pub2-BIB0010|cit10","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1002\/cpt1975186733","article-title":"The efficacy of carbamazepine combinations in epilepsy","volume":"18","author":"Cereghino","year":"1975","journal-title":"Clinical Pharmacology and Therapeutics"},{"issue":"3 Pt 1","key":"10.1002\/14651858.CD002217.pub2-BIB0011|cit11","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1212\/WNL.40.3_Part_1.391","article-title":"Comparative cognitive effects of anticonvulsants","volume":"40","author":"Meador","year":"1990","journal-title":"Neurology"},{"key":"10.1002\/14651858.CD002217.pub2-BIB0012|cit12","unstructured":"Verma G Pathak U Jaiswal V Upadhyay A Comparision of phenobarbitone with phenytoin for the treatment of seizures in term and near term neonates Pediatric Academic Societies Annual Meeting, 1-4 May 2010, Vancouver. Abstract No: 2849.304. http:\/\/www.abstracts2view.com\/pasall\/view.php?nu=PAS10L1_1706 2010"},{"issue":"1","key":"10.1002\/14651858.CD002217.pub2-BIB0013|cit13","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1001\/archneur.1966.00470070035004","article-title":"Relative anticonvulsant potency of primidone","volume":"14","author":"White","year":"1966","journal-title":"Archives of Neurology"},{"key":"10.1002\/14651858.CD002217.pub2-BIB0014|cit14","first-page":"528","article-title":"Phenobarbital and other barbiturates: adverse effects","volume-title":"Antiepileptic Drugs","author":"Baulac","year":"2002"},{"key":"10.1002\/14651858.CD002217.pub2-BIB0015|cit15","doi-asserted-by":"crossref","first-page":"18","DOI":"10.2307\/2527727","article-title":"How to use ridit analysis","volume":"14","author":"Bross","year":"1958","journal-title":"Biometrics"},{"key":"10.1002\/14651858.CD002217.pub2-BIB0016|cit16","volume-title":"Treatment of Early Breast Cancer, Worldwide Evidence, 1985-90","author":"Early Breast Cancer Trialists' Collaborative Group","year":"1990"},{"key":"10.1002\/14651858.CD002217.pub2-BIB0017|cit17","unstructured":"Higgins JPT Green S Cochrane Handbook for Systematic Reviews of Interventions 4.2.4 [updated March 2005] The Cochrane Collaboration"},{"issue":"7","key":"10.1002\/14651858.CD002217.pub2-BIB0018|cit18","doi-asserted-by":"crossref","first-page":"1094","DOI":"10.1111\/j.1528-1167.2006.00585.x","article-title":"ILAE treatment guidelines: Evidence-based analysis of antiepileptic drug efficacy and effectiveness as initial monotherapy for epileptic seizures and syndromes.","volume":"47","author":"Glauser","year":"2006","journal-title":"Epilepsia"},{"key":"10.1002\/14651858.CD002217.pub2-BIB0019|cit19","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1136\/bmj.313.7048.36","article-title":"Trials to assess equivalence; the importance of rigorous methods","volume":"313","author":"Jones","year":"1996","journal-title":"BMJ"},{"key":"10.1002\/14651858.CD002217.pub2-BIB0020|cit20","doi-asserted-by":"crossref","first-page":"c365","DOI":"10.1136\/bmj.c365","article-title":"The impact of outcome reporting bias in randomised controlled trials on a cohort of systematic reviews","volume":"340","author":"Kirkham","year":"2010","journal-title":"BMJ"},{"key":"10.1002\/14651858.CD002217.pub2-BIB0021|cit21","unstructured":"Lefebvre C Manheimer E Glanville J Chapter 6: Searching for studies. In: Higgins JPT, Green S (editors). Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 (updated March 2011). The Cochrane Collaboration, 2011 Available from www.cochrane-handbook.org"},{"issue":"1","key":"10.1002\/14651858.CD002217.pub2-BIB0022|cit22","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.eplepsyres.2008.04.022","article-title":"Pregnancy outcomes in women with epilepsy: A systematic review and meta-analysis of published pregnancy registries and cohorts","volume":"81","author":"Meador","year":"2008","journal-title":"Epilepsy Research"},{"issue":"24","key":"10.1002\/14651858.CD002217.pub2-BIB0023|cit23","doi-asserted-by":"crossref","first-page":"2815","DOI":"10.1002\/(SICI)1097-0258(19981230)17:24<2815::AID-SIM110>3.0.CO;2-8","article-title":"Extracting summary statistics to perform meta-analyses of the published literature for survival endpoints","volume":"17","author":"Parmar","year":"1998","journal-title":"Statistics in Medicine"},{"issue":"3","key":"10.1002\/14651858.CD002217.pub2-BIB0024|cit24","doi-asserted-by":"crossref","first-page":"6","DOI":"10.5070\/D32197W4T4","article-title":"Phenytoin in cutaneous medicine: Its uses, mechanisms and side effects","volume":"9","author":"Scheinfeld","year":"2003","journal-title":"Dermatology Online Journal"},{"key":"10.1002\/14651858.CD002217.pub2-BIB0025|cit25","unstructured":"StataCorp Stata Statistical Software: Release 11 2009"},{"issue":"Suppl 3","key":"10.1002\/14651858.CD002217.pub2-BIB0026|cit26","doi-asserted-by":"crossref","first-page":"S15","DOI":"10.1111\/j.1528-1157.1988.tb05805.x","article-title":"Children of school age: the influence of antiepileptic drugs on behavior and intellect","volume":"29","author":"Trimble","year":"1988","journal-title":"Epilepsia"},{"key":"10.1002\/14651858.CD002217.pub2-BIB0027|cit27","doi-asserted-by":"crossref","first-page":"3337","DOI":"10.1002\/sim.1303","article-title":"Aggregate data meta-analysis with time-to-event outcomes","volume":"21","author":"Williamson","year":"2002","journal-title":"Statistics in Medicine"},{"issue":"4","key":"10.1002\/14651858.CD002217.pub2-BIB0028|cit28","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD002217","article-title":"Phenobarbitone versus phenytoin monotherapy for partial onset seizures and generalized onset tonic-clonic seizures","author":"Taylor","year":"2001","journal-title":"Cochrane Database of Systematic Reviews"}],"updated-by":[{"DOI":"10.1002\/14651858.cd002217.pub3","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2019,7,31]],"date-time":"2019-07-31T00:00:00Z","timestamp":1564531200000}}],"container-title":["Cochrane Database of Systematic Reviews"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full\/10.1002\/14651858.CD002217.pub2","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,2,6]],"date-time":"2022-02-06T17:47:53Z","timestamp":1644169673000},"score":1,"resource":{"primary":{"URL":"https:\/\/doi.wiley.com\/10.1002\/14651858.CD002217.pub2"}},"subtitle":[],"editor":[{"name":"Cochrane Epilepsy Group","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2013,1,31]]},"references-count":28,"URL":"https:\/\/doi.org\/10.1002\/14651858.cd002217.pub2","relation":{},"ISSN":["1465-1858"],"issn-type":[{"value":"1465-1858","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,1,31]]}}}