{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,6]],"date-time":"2026-11-06T07:00:47Z","timestamp":1793948447721,"version":"4.8.0"},"update-to":[{"DOI":"10.1002\/14651858.cd002290.pub5","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2024,11,8]],"date-time":"2024-11-08T00:00:00Z","timestamp":1731024000000}}],"reference-count":246,"publisher":"Wiley","issue":"11","content-domain":{"domain":["wiley.com","cochranelibrary.com"],"crossmark-restriction":true},"short-container-title":[],"DOI":"10.1002\/14651858.cd002290.pub6","type":"journal-article","created":{"date-parts":[[2024,11,8]],"date-time":"2024-11-08T07:03:00Z","timestamp":1731049380000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Non-corticosteroid immunosuppressive medications for steroid-sensitive nephrotic syndrome in children"],"prefix":"10.1002","volume":"2024","author":[{"given":"Nicholas G","family":"Larkins","sequence":"additional","affiliation":[{"name":"Department of Nephrology; Princess Margaret Hospital; Subiaco Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deirdre","family":"Hahn","sequence":"additional","affiliation":[{"name":"Department of Nephrology; The Children's Hospital at Westmead; Westmead Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isaac D","family":"Liu","sequence":"additional","affiliation":[{"name":"Duke-NUS Medical School; Yong Loo Lin School of Medicine; Singapore Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Narelle S","family":"Willis","sequence":"additional","affiliation":[{"name":"Sydney School of Public Health; The University of Sydney; Sydney Australia"},{"name":"Cochrane Kidney and Transplant, Centre for Kidney Research; The Children's Hospital at Westmead; Westmead Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathan C","family":"Craig","sequence":"additional","affiliation":[{"name":"Cochrane Kidney and Transplant, Centre for Kidney Research; The Children's Hospital at Westmead; Westmead Australia"},{"name":"College of Medicine and Public Health; Flinders University; Adelaide Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elisabeth M","family":"Hodson","sequence":"additional","affiliation":[{"name":"Cochrane Kidney and Transplant, Centre for Kidney Research; The Children's Hospital at Westmead; Westmead Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,11,8]]},"reference":[{"issue":"10","key":"10.1002\/14651858.CD002290.pub6-BIB0001|cit1","first-page":"1503","article-title":"Efficacy of levamisole as a single agent in maintaining remission in steroid dependant nephrotic syndrome [abstract no: COD.OC.5]","volume":"21","author":"Abeyagunawardena","year":"2006","journal-title":"Pediatric Nephrology"},{"issue":"10","key":"10.1002\/14651858.CD002290.pub6-BIB0002|cit2","first-page":"1535","article-title":"Intravenous pulsed vs oral cyclophosphamide therapy in steroid dependant nephrotic syndrome [abstract no: COD.PP 54]","volume":"21","author":"Abeyagunawardena","year":"2006","journal-title":"Pediatric Nephrology"},{"issue":"9","key":"10.1002\/14651858.CD002290.pub6-BIB0003|cit3","first-page":"1547","article-title":"Intravenous pulsed cyclophosphamide versus vincristine therapy in steroid dependant nephrotic syndrome: a randomised controlled trial [abstract no: 550P]","volume":"22","author":"Abeyagunawardena","year":"2007","journal-title":"Pediatric Nephrology"},{"issue":"2","key":"10.1002\/14651858.CD002290.pub6-BIB0004|cit4","doi-asserted-by":"crossref","first-page":"A1","DOI":"10.1016\/j.krcp.2014.05.017","article-title":"Efficacy and safety of rituximab in children with refractory nephrotic syndrome: a multicenter clinical trial [abstract]","volume":"33","author":"Ahn","year":"2014","journal-title":"Kidney Research & Clinical Practice"},{"issue":"46","key":"10.1002\/14651858.CD002290.pub6-BIB0005|cit5","doi-asserted-by":"crossref","first-page":"e13157","DOI":"10.1097\/MD.0000000000013157","article-title":"Efficacy and safety of rituximab in childhood-onset, difficult-to-treat nephrotic syndrome: a multicenter open-label trial in Korea","volume":"97","author":"Ahn","year":"2018","journal-title":"Medicine"},{"issue":"8","key":"10.1002\/14651858.CD002290.pub6-BIB0006|cit6","first-page":"1361","article-title":"Efficacy and safety of rituximab in children with refractory nephrotic syndrome: a multicenter clinical trial [abstract no: O39]","volume":"28","author":"Anh","year":"2013","journal-title":"Pediatric Nephrology"},{"key":"10.1002\/14651858.CD002290.pub6-BIB0007|cit7","first-page":"222","article-title":"Controlled trial of chlorambucil in frequently relapsing nephrotic syndrome in children (a preliminary report)","volume":"61 Suppl 1","author":"Alatas","year":"1978","journal-title":"Journal of the Medical Association of Thailand"},{"issue":"2","key":"10.1002\/14651858.CD002290.pub6-BIB0008|cit8","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1007\/s00467-005-2080-9","article-title":"Experience with levamisole in frequently relapsing, steroid-dependent nephrotic syndrome","volume":"21","author":"Al-Saran","year":"2006","journal-title":"Pediatric Nephrology"},{"issue":"9","key":"10.1002\/14651858.CD002290.pub6-BIB0009|cit9","first-page":"C93","article-title":"Experience with levamisole in FR\/SD childhood nephrotic syndrome in a large Saudi center [abstract no: PO03]","volume":"19","author":"Al-Saran","year":"2004","journal-title":"Pediatric Nephrology"},{"issue":"8","key":"10.1002\/14651858.CD002290.pub6-BIB0010|cit10","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1056\/NEJM198202253060803","article-title":"Effect of cytotoxic drugs in frequently relapsing nephrotic syndrome with and without steroid dependence","volume":"306","year":"1982","journal-title":"New England Journal of Medicine"},{"issue":"3","key":"10.1002\/14651858.CD002290.pub6-BIB0011|cit11","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1055\/s-2008-1033800","article-title":"The treatment of minimal change nephrotic syndrome (lipoid nephrosis): cooperative studies of the Arbeitsgemeinschaft fur Padiatrische Nephrologie (APN)","volume":"194","author":"Brodehl","year":"1982","journal-title":"Klinische Padiatrie"},{"key":"10.1002\/14651858.CD002290.pub6-BIB0012|cit12","first-page":"C26","article-title":"Results of the nephrotic syndrome study VIII of the APN: new standard treatment versus new standard treatment plus 8 weeks cyclosporin A [abstract]","volume":"13","year":"1999","journal-title":"Pediatric Nephrology"},{"issue":"4","key":"10.1002\/14651858.CD002290.pub6-BIB0013|cit13","doi-asserted-by":"crossref","first-page":"1151\u20137","DOI":"10.1681\/ASN.2005090922","article-title":"Initial treatment of idiopathic nephrotic syndrome in children: prednisone versus prednisone plus cyclosporine A: a prospective, randomized trial","volume":"17","author":"Hoyer","year":"2006","journal-title":"Journal of the American Society of Nephrology"},{"issue":"Program & Abstr","key":"10.1002\/14651858.CD002290.pub6-BIB0014|cit14","first-page":"104A","article-title":"Results of the nephrotic syndrome study VIII of the APN: new standard treatment versus new standard treatment plus 8 weeks cyclosporin A [abstract]","volume":"10","author":"Hoyer","year":"1999","journal-title":"Journal of the American Society of Nephrology"},{"issue":"6","key":"10.1002\/14651858.CD002290.pub6-BIB0015|cit15","first-page":"C91","article-title":"The initial treatment of idiopathic nephrotic syndrome with prednisone and cyclosporin A: preliminary results of a therapeutic trial [abstract no: P147]","volume":"9","author":"Hoyer","year":"1995","journal-title":"Pediatric Nephrology"},{"issue":"12","key":"10.1002\/14651858.CD002290.pub6-BIB0016|cit16","doi-asserted-by":"crossref","first-page":"1859","DOI":"10.2215\/CJN.06890618","article-title":"Adrenocorticotropic hormone for childhood nephrotic syndrome: the ATLANTIS randomized trial","volume":"13","author":"Wang","year":"2018","journal-title":"Clinical Journal of the American Society of Nephrology: CJASN"},{"issue":"2","key":"10.1002\/14651858.CD002290.pub6-BIB0017|cit17","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/S0022-3476(78)80030-4","article-title":"Chlorambucil dosage in frequently relapsing nephrotic syndrome: a controlled clinical trial","volume":"92","author":"Baluarte","year":"1978","journal-title":"Journal of Pediatrics"},{"issue":"10","key":"10.1002\/14651858.CD002290.pub6-BIB0018|cit18","doi-asserted-by":"crossref","first-page":"2969","DOI":"10.1007\/s00467-024-06402-9","article-title":"Daily compared with alternate-day levamisole in pediatric nephrotic syndrome: an open-label randomized controlled study","volume":"39","author":"Banerjee","year":"2024","journal-title":"Pediatric Nephrology"},{"issue":"8757","key":"10.1002\/14651858.CD002290.pub6-BIB0019|cit19","doi-asserted-by":"crossref","first-page":"1555","DOI":"10.1016\/0140-6736(91)93257-A","article-title":"Levamisole for corticosteroid-dependent nephrotic syndrome in childhood. British Association for Paediatric Nephrology","volume":"337","year":"1991","journal-title":"Lancet"},{"key":"10.1002\/14651858.CD002290.pub6-BIB0020|cit20","first-page":"95","article-title":"A controlled trial of cyclophosphamide in steroid sensitive relapsing nephrotic syndrome of childhood [abstract]","volume":"8","author":"Barratt","year":"1971","journal-title":"Nephron"},{"issue":"7671","key":"10.1002\/14651858.CD002290.pub6-BIB0021|cit21","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1016\/S0140-6736(70)90108-X","article-title":"Controlled trial of cyclophosphamide in steroid-sensitive relapsing nephrotic syndrome of childhood","volume":"296","author":"Barratt","year":"1970","journal-title":"Lancet"},{"issue":"4","key":"10.1002\/14651858.CD002290.pub6-BIB0022|cit22","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1136\/adc.48.4.286","article-title":"Comparative trial of 2 weeks and 8 weeks cyclophosphamide in steroid-sensitive relapsing nephrotic syndrome of childhood","volume":"48","author":"Barratt","year":"1973","journal-title":"Archives of Disease in Childhood"},{"issue":"6","key":"10.1002\/14651858.CD002290.pub6-BIB0023|cit23","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1136\/adc.52.6.462","article-title":"Controlled trial of azathioprine in treatment of steroid-responsive nephrotic syndrome of childhood","volume":"52","author":"Barratt","year":"1977","journal-title":"Archives of Disease in Childhood"},{"issue":"7","key":"10.1002\/14651858.CD002290.pub6-BIB0024|cit24","doi-asserted-by":"publisher","first-page":"2268","DOI":"10.1007\/s00467-022-05865-y","article-title":"Mycophenolate mofetil (MMF) versus cyclophosphamide (CYC) to prevent relapse in children with steroid-dependent nephrotic syndrome (SDNS): a multicentrer, randomized, controlled trial [abstract no: O-27]","volume":"38","author":"Baudouin","year":"2023","journal-title":"Pediatric Nephrology"},{"issue":"11","key":"10.1002\/14651858.CD002290.pub6-BIB0025|cit25","doi-asserted-by":"publisher","first-page":"2857","DOI":"10.1007\/s00467-022-05630-1","article-title":"Mycophenolate mofetil (MMF) versus cyclophosphamide (CYC) to prevent relapse in children with steroid-dependent nephrotic syndrome (SDNS): a multicentrer, randomized, controlled trial [abstract no: P1-96]","volume":"37","author":"Baudouin","year":"2022","journal-title":"Pediatric Nephrology"},{"key":"10.1002\/14651858.CD002290.pub6-BIB0026|cit26","first-page":"26","article-title":"Comparative study of prednisolone alone and prednisolone plus fusidic acid in the treatment of children with steroid-responsive nephrotic syndrome","volume":"41 Suppl 1","author":"Cerkauskiene","year":"2005","journal-title":"Medicina (Kaunas, Lithuania)"},{"issue":"4","key":"10.1002\/14651858.CD002290.pub6-BIB0027|cit27","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1016\/S0022-3476(73)80585-2","article-title":"A controlled prospective study of cyclophosphamide in relapsing, corticosteroid-responsive, minimal-lesion nephrotic syndrome in childhood","volume":"82","author":"Chiu","year":"1973","journal-title":"Journal of Pediatrics"},{"issue":"4","key":"10.1002\/14651858.CD002290.pub6-BIB0028|cit28","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1159\/000187855","article-title":"Use of levamisole in maintaining remission in steroid-sensitive nephrotic syndrome in children [Erratum in: Nephron 1994;67(4):507]","volume":"66","author":"Dayal","year":"1994","journal-title":"Nephron"},{"key":"10.1002\/14651858.CD002290.pub6-BIB0029|cit29","unstructured":"Donia A Ammar H Moustafa F Sobh M Long-term efficacy of two unconventional adjunctive therapies in minimal change nephrotic children [abstract no: SP062] 41st Congress. European Renal Association. European Dialysis and Transplantation Association; 2004 May 15-18; Lisbon, Portugal 2004 37"},{"issue":"10","key":"10.1002\/14651858.CD002290.pub6-BIB0030|cit30","doi-asserted-by":"crossref","first-page":"1420","DOI":"10.1007\/s00467-005-1943-4","article-title":"Long-term results of two unconventional agents in steroid-dependent nephrotic children","volume":"20","author":"Donia","year":"2005","journal-title":"Pediatric Nephrology"},{"issue":"9","key":"10.1002\/14651858.CD002290.pub6-BIB0031|cit31","first-page":"1442","article-title":"Randomized controlled trial of mycophenolate mofetil (MMF) versus cyclosporine A (CsA) in children with frequently relapsing nephrotic syndrome [abstract no: 28FC]","volume":"22","author":"Dorresteijn","year":"2007","journal-title":"Pediatric Nephrology"},{"issue":"9","key":"10.1002\/14651858.CD002290.pub6-BIB0032|cit32","first-page":"1865","article-title":"Intestinal permeability in patients treated with mycophenolate mofetil (MMF) for nephrotic syndrome (NS) [abstract no: 355]","volume":"25","author":"Dorresteijn","year":"2010","journal-title":"Pediatric Nephrology"},{"issue":"11","key":"10.1002\/14651858.CD002290.pub6-BIB0033|cit33","doi-asserted-by":"crossref","first-page":"2013","DOI":"10.1007\/s00467-008-0899-6","article-title":"Mycophenolate mofetil versus cyclosporine for remission maintenance in nephrotic syndrome","volume":"23","author":"Dorresteijn","year":"2008","journal-title":"Pediatric Nephrology"},{"issue":"9","key":"10.1002\/14651858.CD002290.pub6-BIB0034|cit34","first-page":"1579","article-title":"Frequently relapsing steroid-sensitive nephrotic syndrome (SSNS) in children and adolescents: treatment with mycophenolate mofetil (MMF) vs. cyclosporin A (CsA) [abstract no: OS3-FRI-172]","volume":"26","author":"Gellermann","year":"2011","journal-title":"Pediatric Nephrology"},{"issue":"12","key":"10.1002\/14651858.CD002290.pub6-BIB0035|cit35","doi-asserted-by":"crossref","first-page":"2411","DOI":"10.1007\/s00467-014-2913-5","article-title":"Serum suPAR levels are modulated by immunosuppressive therapy of minimal change nephrotic syndrome","volume":"29","author":"Gellermann","year":"2014","journal-title":"Pediatric Nephrology"},{"issue":"10","key":"10.1002\/14651858.CD002290.pub6-BIB0036|cit36","doi-asserted-by":"crossref","first-page":"1689","DOI":"10.1681\/ASN.2012121200","article-title":"Mycophenolate mofetil versus cyclosporin A in children with frequently relapsing nephrotic syndrome","volume":"24","author":"Gellermann","year":"2013","journal-title":"Journal of the American Society of Nephrology"},{"issue":"Abstracts","key":"10.1002\/14651858.CD002290.pub6-BIB0037|cit37","first-page":"1","article-title":"A randomized cross-over multicenter trial of mycophenolate mofetil versus cyslosporin A in children with frequently relapsing nephrotic syndrome [abstract no: LB-OR04]","volume":"22","author":"Querfeld","year":"2011","journal-title":"Journal of the American Society of Nephrology"},{"issue":"9","key":"10.1002\/14651858.CD002290.pub6-BIB0038|cit38","first-page":"651","article-title":"Mycophenolate mofetil versus cyclosporine A in children with primary refractory nephrotic syndrome","volume":"56","author":"Geng","year":"2018","journal-title":"Zhonghua Erke Zazhi"},{"issue":"14","key":"10.1002\/14651858.CD002290.pub6-BIB0039|cit39","doi-asserted-by":"crossref","first-page":"746","DOI":"10.1056\/NEJM197609302951402","article-title":"Chlorambucil treatment of frequently relapsing nephrotic syndrome","volume":"295","author":"Grupe","year":"1976","journal-title":"New England Journal of Medicine"},{"issue":"9","key":"10.1002\/14651858.CD002290.pub6-BIB0040|cit40","first-page":"1712","article-title":"The levamisole study in steroid sensitive idiopathic nephrotic syndrome (SSINS): inclusion completed [abstract no: P150]","volume":"27","author":"Gruppen","year":"2012","journal-title":"Pediatric Nephrology"},{"issue":"10","key":"10.1002\/14651858.CD002290.pub6-BIB0041|cit41","first-page":"1753","article-title":"Levamisole increases the time to relapse in children with steroid-sensitive idiopathic nephrotic syndrome: Results of a multi-center, double-blind, placebo-controlled, randomized clinical trial [abstract no: FP-S25-11]","volume":"31","author":"Gruppen","year":"2016","journal-title":"Pediatric Nephrology"},{"key":"10.1002\/14651858.CD002290.pub6-BIB0042|cit42","first-page":"1651","article-title":"First aid in performing international paediatric clinical drug trials using the experience of the levamisole trial [abstract no: P219]","volume":"23","author":"Gruppen","year":"2008","journal-title":"Pediatric Nephrology"},{"issue":"9","key":"10.1002\/14651858.CD002290.pub6-BIB0043|cit43","first-page":"1682","article-title":"The levamisole study in steroid sensitive idiopathic nephrotic syndrome (SSINS): completion is approaching [abstract no: PS2-FRI-537]","volume":"26","author":"Gruppen","year":"2011","journal-title":"Pediatric Nephrology"},{"issue":"2","key":"10.1002\/14651858.CD002290.pub6-BIB0044|cit44","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1016\/j.kint.2017.08.011","article-title":"A randomized clinical trial indicates that levamisole increases the time to relapse in children with steroid-sensitive idiopathic nephrotic syndrome","volume":"93","author":"Gruppen","year":"2018","journal-title":"Kidney international"},{"issue":"10","key":"10.1002\/14651858.CD002290.pub6-BIB0045|cit45","first-page":"1531","article-title":"Levamisole in steroid-sensitive nephrotic syndrome (SSNS): an international multicenter double-blind randomized trial: the last news [abstract no: COD.PP40]","volume":"21","author":"Gruppen","year":"2006","journal-title":"Pediatric Nephrology"},{"issue":"2","key":"10.1002\/14651858.CD002290.pub6-BIB0046|cit46","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1111\/bcp.12607","article-title":"Population pharmacokinetics of levamisole in children with steroid-sensitive nephrotic syndrome","volume":"80","author":"Kreeftmeijer-Vegter","year":"2015","journal-title":"British Journal of Clinical Pharmacology"},{"issue":"Abstracts","key":"10.1002\/14651858.CD002290.pub6-BIB0047|cit47","first-page":"6B","article-title":"Cyclosporine C2 monitoring for frequent-relapsing nephrotic syndrome in children: a multicenter randomized controlled trial [abstract no: LB-PO3157]","volume":"22","author":"Iijima","year":"2011","journal-title":"Journal of the American Society of Nephrology"},{"issue":"2","key":"10.1002\/14651858.CD002290.pub6-BIB0048|cit48","doi-asserted-by":"crossref","first-page":"271","DOI":"10.2215\/CJN.13071212","article-title":"Cyclosporine C2 monitoring for the treatment of frequently relapsing nephrotic syndrome in children: a multicenter randomized phase II trial","volume":"9","author":"Iijima","year":"2014","journal-title":"Clinical Journal of the American Society of Nephrology: CJASN"},{"issue":"8","key":"10.1002\/14651858.CD002290.pub6-BIB0049|cit49","first-page":"1596","article-title":"Cyclosporine C2 monitoring for the treatment of frequently relapsing nephrotic syndrome in children: a multicenter randomized trial [abstract no: P-SUN191]","volume":"28","author":"Nakamura","year":"2013","journal-title":"Pediatric Nephrology"},{"issue":"9950","key":"10.1002\/14651858.CD002290.pub6-BIB0050|cit50","doi-asserted-by":"crossref","first-page":"1273","DOI":"10.1016\/S0140-6736(14)60541-9","article-title":"Rituximab for childhood-onset, complicated, frequently relapsing nephrotic syndrome or steroid-dependent nephrotic syndrome: a multicentre, double-blind, randomised, placebo-controlled trial","volume":"384","author":"Iijima","year":"2014","journal-title":"Lancet"},{"issue":"8","key":"10.1002\/14651858.CD002290.pub6-BIB0051|cit51","first-page":"1362","article-title":"Multicenter, double-blind, placebo-controlled, randomized trial of rituximab for the treatment of childhood-onset refractory nephrotic syndrome [abstract no: O-41]","volume":"28","author":"Iijima","year":"2013","journal-title":"Pediatric Nephrology"},{"issue":"1","key":"10.1002\/14651858.CD002290.pub6-BIB0052|cit52","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1007\/s40124-014-0065-5","article-title":"Rituximab treatment for nephrotic syndrome in children","volume":"3","author":"Iijima","year":"2015","journal-title":"Current Pediatric Reports"},{"issue":"Abstracts","key":"10.1002\/14651858.CD002290.pub6-BIB0053|cit53","first-page":"5B","article-title":"Multicenter double-blind, randomized, placebo-controlled trial of rituximab for the treatment of childhood-onset refractory nephrotic syndrome [abstract no: SA-PO1102]","volume":"23","author":"Iijima","year":"2014","journal-title":"Journal of the American Society of Nephrology"},{"key":"10.1002\/14651858.CD002290.pub6-BIB0054|cit54","unstructured":"Iijima K Tsuchida N Sako M Multicenter double-blind, randomized, placebo-controlled trial of IDEC-C2B8 for the treatment of childhood-onset complicated nephrotic syndrome: clinical study protocol Number: RCRNS-01 Version: 4.0 www.med.kobe-u.ac.jp\/pediat\/pdf\/rcrn01.pdf"},{"issue":"5","key":"10.1002\/14651858.CD002290.pub6-BIB0055|cit55","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1111\/j.1442-200X.2011.03432.x","article-title":"Rituximab for childhood refractory nephrotic syndrome","volume":"53","author":"Iijima","year":"2011","journal-title":"Pediatrics International"},{"issue":"Suppl 2","key":"10.1002\/14651858.CD002290.pub6-BIB0056|cit56","first-page":"S82","article-title":"Rituximab for childhood-onset, complicated, frequently relapsing nephrotic syndrome or steroid-dependent nephrotic syndrome: an investigator initiated, multicenter, double-blind, randomized, placebo-controlled trial [abstract]","volume":"42","author":"Iijima","year":"2011","journal-title":"Japanese Journal of Pharmacology & Therapeutics"},{"issue":"11","key":"10.1002\/14651858.CD002290.pub6-BIB0057|cit57","doi-asserted-by":"crossref","first-page":"2071","DOI":"10.1007\/s00467-017-3718-0","article-title":"Long-term outcome of childhood-onset complicated nephrotic syndrome after a multicenter, double-blind, randomized, placebo-controlled trial of rituximab","volume":"32","author":"Kamei","year":"2017","journal-title":"Pediatric Nephrology"},{"issue":"1","key":"10.1002\/14651858.CD002290.pub6-BIB0058|cit58","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1186\/s12882-018-1099-7","article-title":"Study protocol: mycophenolate mofetil as maintenance therapy after rituximab treatment for childhood-onset, complicated, frequently-relapsing nephrotic syndrome or steroid-dependent nephrotic syndrome: a multicenter double-blind, randomized, placebo-controlled trial (JSKDC07)","volume":"19","author":"Horinouchi","year":"2018","journal-title":"BMC Nephrology"},{"issue":"2","key":"10.1002\/14651858.CD002290.pub6-BIB0059|cit59","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1681\/ASN.2021050643","article-title":"Mycophenolate mofetil after rituximab for childhood-onset complicated frequently-relapsing or steroid-dependent nephrotic syndrome","volume":"33","author":"Iijima","year":"2022","journal-title":"Journal of the American Society of Nephrology"},{"issue":"1","key":"10.1002\/14651858.CD002290.pub6-BIB0060|cit60","first-page":"32","article-title":"Comparison of efficacy of levamisole versus mycophenolate mofetilin children with frequently relapsing steroid sensitive nephrotic syndrome","volume":"62","author":"Ishaq","year":"2023","journal-title":"Pakistan Journal of Medical Research"},{"issue":"10","key":"10.1002\/14651858.CD002290.pub6-BIB0061|cit61","doi-asserted-by":"crossref","first-page":"1167","DOI":"10.1038\/ki.2008.24","article-title":"Effective and safe treatment with cyclosporine in nephrotic children: a prospective, randomized multicenter trial","volume":"73","author":"Ishikura","year":"2008","journal-title":"Kidney International"},{"issue":"9","key":"10.1002\/14651858.CD002290.pub6-BIB0062|cit62","first-page":"1531","article-title":"A 2-year, prospective, randomized, multicenter trial of cyclosporine in children with frequently relapsing nephrotic syndrome [abstract no: 497P]","volume":"22","author":"Ishikura","year":"2007","journal-title":"Pediatric Nephrology"},{"issue":"3","key":"10.1002\/14651858.CD002290.pub6-BIB0063|cit63","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1007\/s00467-014-2955-8","article-title":"Morbidity in children with frequently relapsing nephrosis: 10-year follow-up of a randomized controlled trial","volume":"30","author":"Ishikura","year":"2015","journal-title":"Pediatric Nephrology"},{"issue":"7654","key":"10.1002\/14651858.CD002290.pub6-BIB0064|cit64","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1016\/S0140-6736(70)91093-7","article-title":"Controlled trial of azathioprine in children with nephrotic syndrome. A report for the International Study of Kidney Disease in Children","volume":"1","author":"Abramowicz","year":"1970","journal-title":"Lancet"},{"key":"10.1002\/14651858.CD002290.pub6-BIB0065|cit65","first-page":"95","article-title":"International trial of azathioprine in nephrotic syndrome in childhood [abstract]","volume":"8","author":"Arneil","year":"1971","journal-title":"Nephron"},{"issue":"7878","key":"10.1002\/14651858.CD002290.pub6-BIB0066|cit66","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1016\/S0140-6736(74)91814-5","article-title":"Prospective, controlled trial of cyclophosphamide therapy in children with nephrotic syndrome. Report of the International Study of Kidney Disease in Children","volume":"304","year":"1974","journal-title":"Lancet"},{"issue":"12","key":"10.1002\/14651858.CD002290.pub6-BIB0067|cit67","doi-asserted-by":"crossref","first-page":"3117-26","DOI":"10.1007\/s00467-022-05475-8","article-title":"Efficacy of rituximab versus tacrolimus in difficult-to-treat steroid-sensitive nephrotic syndrome: an open-label pilot randomized controlled trial","volume":"37","author":"Mathew","year":"2022","journal-title":"Pediatric Nephrology"},{"issue":"4 Suppl","key":"10.1002\/14651858.CD002290.pub6-BIB0068|cit68","doi-asserted-by":"crossref","first-page":"S198","DOI":"10.1016\/j.ekir.2021.03.483","article-title":"Efficacy and safety of rituximab versus tacrolimus in frequently relapsing nephrotic syndrome: an open label randomized controlled trial [abstract no: POS-457]","volume":"6","author":"Mathew","year":"2021","journal-title":"Kidney International Reports"},{"key":"10.1002\/14651858.CD002290.pub6-BIB0069|cit69","first-page":"2922","article-title":"Efficacy and safety of rituximab versus tacrolimus in frequently relapsing nephrotic syndrome: an open label randomized controlled trial with non-inferiority design [abstract no: ACPN210330P03]","volume":"36","author":"Mathew","year":"2021","journal-title":"Pediatric Nephrology"},{"issue":"2","key":"10.1002\/14651858.CD002290.pub6-BIB0070|cit70","first-page":"97","article-title":"Efficacy and safety of rituximab versus tacrolimus in frequently relapsing nephrotic syndrome: an open-label randomized controlled trial [abstract no:S14]","volume":"3","author":"Mathew","year":"2020","journal-title":"Asian Journal of Pediatric Nephrology"},{"issue":"Abstract Suppl","key":"10.1002\/14651858.CD002290.pub6-BIB0071|cit71","first-page":"28","article-title":"Efficacy and safety of rituximab versus tacrolimus in frequently relapsing nephrotic syndrome: An open label randomized controlled trial with non-inferiority design [abstract no: ACPN210330P]","volume":"4","author":"Mathew","year":"2021","journal-title":"Asian Pediatric Journal of Nephrology"},{"issue":"4","key":"10.1002\/14651858.CD002290.pub6-BIB0072|cit72","doi-asserted-by":"crossref","first-page":"614","DOI":"10.1016\/S0022-3476(73)80586-4","article-title":"Therapeutic and toxic effects observed with different dosage programs of cyclophosphamide in treatment of steroid-responsive but frequently relapsing nephrotic syndrome","volume":"82","author":"McCrory","year":"1973","journal-title":"Journal of Pediatrics"},{"issue":"7","key":"10.1002\/14651858.CD002290.pub6-BIB0073|cit73","doi-asserted-by":"publisher","first-page":"2268","DOI":"10.1007\/s00467-022-05865-y","article-title":"Efficacy of levamisole for maintaining remission after the first flare of steroid sensitive nephrotic syndrome in children: the NEPHROVIR-3 randomized controlled trial [abstract no: O-26]","volume":"38","author":"Dossier","year":"2023","journal-title":"Pediatric Nephrology"},{"issue":"11","key":"10.1002\/14651858.CD002290.pub6-BIB0074|cit74","first-page":"2818","article-title":"Efficacy of levamisole for maintaining remission after the first flare of steroid sensitive nephrotic syndrome in children: the NEPHROVIR-3 randomized controlled trial [abstract no: OP-39]","volume":"37","author":"Dossier","year":"2022","journal-title":"Pediatric Nephrology"},{"issue":"Suppl 3","key":"10.1002\/14651858.CD002290.pub6-BIB0075|cit75","first-page":"i803","article-title":"Efficacy of levamisole for maintaining remission after the first flare of steroid sensitive nephrotic syndrome in children: the NEPHROVIR-3 randomized controlled trial [abstract no: FC038]","volume":"37","author":"Dossier","year":"2022","journal-title":"Nephrology Dialysis Transplantation"},{"key":"10.1002\/14651858.CD002290.pub6-BIB0076|cit76","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/j.jaut.2017.10.006","article-title":"NEPHRUTIX: A randomized, double-blind, placebo vs rituximab-controlled trial assessing T-cell subset changes in minimal change nephrotic syndrome","volume":"88","author":"Boumediene","year":"2018","journal-title":"Journal of Autoimmunity"},{"issue":"1","key":"10.1002\/14651858.CD002290.pub6-BIB0077|cit77","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/BF00856817","article-title":"Comparison of cyclosporin and chlorambucil in the treatment of steroid-dependent idiopathic nephrotic syndrome: a multicentre randomized controlled trial. The French Society of Paediatric Nephrology","volume":"6","author":"Niaudet","year":"1992","journal-title":"Pediatric Nephrology"},{"key":"10.1002\/14651858.CD002290.pub6-BIB0078|cit78","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1159\/000415387","article-title":"Unconjugated hyperbilirubinemia due to ciclosporin administration in children with nephrotic syndrome","volume":"67","author":"Edefonti","year":"1988","journal-title":"Contributions to Nephrology"},{"issue":"4","key":"10.1002\/14651858.CD002290.pub6-BIB0079|cit79","first-page":"C8","article-title":"Unconjugated hyperbilirubinemia due to cyclosporin A (CyA) administration in children with nephrotic syndrome (NS) [abstract no: F1.12]","volume":"1","author":"Edefonti","year":"1987","journal-title":"Pediatric Nephrology"},{"issue":"3","key":"10.1002\/14651858.CD002290.pub6-BIB0080|cit80","first-page":"310","article-title":"Cyclosporine (CSA) vs cyclophosphamide (CYC) for children with frequently relapsing\/steroid dependent nephrotic syndrome (FR\/SDNS): long term study [abstract]","volume":"3","author":"Edefonti","year":"1992","journal-title":"Journal of the American Society of Nephrology"},{"key":"10.1002\/14651858.CD002290.pub6-BIB0081|cit81","unstructured":"Edefonti A Ghio L Rizzoni G Rinaldi S Gusmano R Lama G Cyclosporine (CSA) vs cyclophosphamide (CYC) for children with frequently relapsing\/steroid dependent nephrotic syndrome: long term study [abstract] 9th Congress of the International Pediatric Nephrology Association; 1992 Aug 30-Sep 4; Jerusalem, Israel 1992 C70"},{"issue":"12","key":"10.1002\/14651858.CD002290.pub6-BIB0082|cit82","doi-asserted-by":"crossref","first-page":"1326","DOI":"10.1093\/ndt\/8.12.1326","article-title":"Cyclosporin versus cyclophosphamide for patients with steroid-dependent and frequently relapsing idiopathic nephrotic syndrome: a multicentre randomized controlled trial","volume":"8","author":"Ponticelli","year":"1993","journal-title":"Nephrology Dialysis Transplantation"},{"key":"10.1002\/14651858.CD002290.pub6-BIB0083|cit83","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1159\/000168206","article-title":"Ciclosporin in minimal-change glomerulopathy and in focal segmental glomerular sclerosis","volume":"10 Suppl 1","author":"Ponticelli","year":"1990","journal-title":"American Journal of Nephrology"},{"issue":"2","key":"10.1002\/14651858.CD002290.pub6-BIB0084|cit84","first-page":"147","article-title":"A multicenter controlled prospective trial with cyclosporine vs cyclophosphamide in frequent relapsers and steroid dependent patients with idiopathic nephrotic syndrome","volume":"2","author":"Ponticelli","year":"1989","journal-title":"Journal of Nephrology"},{"key":"10.1002\/14651858.CD002290.pub6-BIB0085|cit85","unstructured":"Ponticelli C Ciclosporin in the treatment of idiopathic nephrotic syndrome [abstract] 10th Asian Colloquium in Nephrology; 1994 Dec 2-6; Karachi, Pakistan 1994 116"},{"issue":"5","key":"10.1002\/14651858.CD002290.pub6-BIB0086|cit86","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1111\/j.1651-2227.1993.tb12723.x","article-title":"Renal effects of cyclosporin A in children treated for idiopathic nephrotic syndrome","volume":"82","author":"Tirelli","year":"1993","journal-title":"Acta Paediatrica"},{"issue":"5","key":"10.1002\/14651858.CD002290.pub6-BIB0087|cit87","doi-asserted-by":"crossref","first-page":"494","DOI":"10.1007\/s00467-003-1404-x","article-title":"Pulse cyclophosphamide therapy in steroid-dependent nephrotic syndrome","volume":"19","author":"Prasad","year":"2004","journal-title":"Pediatric Nephrology"},{"issue":"1","key":"10.1002\/14651858.CD002290.pub6-BIB0088|cit88","first-page":"6","article-title":"Levamisole in the treatment of steroid dependent or frequent relapsing nephrotic syndrome in children","volume":"15","author":"Rashid","year":"1996","journal-title":"Bangladesh Renal Journal"},{"issue":"6","key":"10.1002\/14651858.CD002290.pub6-BIB0089|cit89","doi-asserted-by":"crossref","first-page":"1308","DOI":"10.2215\/CJN.09421010","article-title":"Short-term effects of rituximab in children with steroid- and calcineurin-dependent nephrotic syndrome: a randomized controlled trial","volume":"6","author":"Ravani","year":"2011","journal-title":"Clinical Journal of the American Society of Nephrology: CJASN"},{"issue":"9","key":"10.1002\/14651858.CD002290.pub6-BIB0090|cit90","doi-asserted-by":"crossref","first-page":"2259","DOI":"10.1681\/ASN.2014080799","article-title":"Rituximab in children with steroid-dependent nephrotic syndrome: a multicenter, open-label, noninferiority, randomized controlled trial","volume":"26","author":"Ravani","year":"2015","journal-title":"Journal of the American Society of Nephrology"},{"issue":"Abstract Suppl","key":"10.1002\/14651858.CD002290.pub6-BIB0091|cit91","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1681\/ASN.20213210S149a","article-title":"Antibodies anti-rituximab do not affect response to rituximab in idiopathic nephrotic syndrome [abstract no: SA-OR33]","volume":"32","author":"Angeletti","year":"2021","journal-title":"Journal of the American Society of Nephrology"},{"key":"10.1002\/14651858.CD002290.pub6-BIB0092|cit92","doi-asserted-by":"publisher","first-page":"584-5","DOI":"10.1681\/ASN.20233411S1584d","article-title":"Multi-omic serum profiling in children and young adults affected by steroid-dependent nephrotic syndrome [abstract no: FR-PO662]","volume":"34","author":"Bruschi","year":"2023","journal-title":"Journal of the American Society of Nephrology"},{"key":"10.1002\/14651858.CD002290.pub6-BIB0093|cit93","doi-asserted-by":"crossref","first-page":"726428","DOI":"10.3389\/fimmu.2021.726428","article-title":"CyTOF-enabled analysis identifies class-switched B cells as the main lymphocyte subset associated with disease relapse in children with idiopathic nephrotic syndrome","volume":"12","author":"Fribourg","year":"2021","journal-title":"Frontiers in Immunology"},{"issue":"3","key":"10.1002\/14651858.CD002290.pub6-BIB0094|cit94","doi-asserted-by":"crossref","first-page":"e013319","DOI":"10.1136\/bmjopen-2016-013319","article-title":"Randomised controlled trial comparing ofatumumab to rituximab in children with steroid-dependent and calcineurin inhibitor-dependent idiopathic nephrotic syndrome: study protocol","volume":"7","author":"Ravani","year":"2017","journal-title":"BMJ Open"},{"issue":"Suppl 1","key":"10.1002\/14651858.CD002290.pub6-BIB0095|cit95","first-page":"i89","article-title":"Ofatumumab or rituximab for children with steroid-dependent nephrotic syndrome. A randomized controlled trial [abstract no: FC 131]","volume":"36","author":"Ravani","year":"2021","journal-title":"Nephrology Dialysis Transplantation"},{"issue":"10","key":"10.1002\/14651858.CD002290.pub6-BIB0096|cit96","doi-asserted-by":"crossref","first-page":"2652","DOI":"10.1681\/ASN.2021040561","article-title":"Human or chimeric monoclonal anti-CD20 antibodies for children with nephrotic syndrome: a superiority randomized trial","volume":"32","author":"Ravani","year":"2021","journal-title":"Journal of the American Society of Nephrology"},{"issue":"8","key":"10.1002\/14651858.CD002290.pub6-BIB0097|cit97","doi-asserted-by":"crossref","first-page":"1437","DOI":"10.1007\/s00467-020-04540-4","article-title":"Rituximab for very low dose steroid-dependent nephrotic syndrome in children: a randomized controlled study","volume":"35","author":"Ravani","year":"2020","journal-title":"Pediatric Nephrology"},{"issue":"8","key":"10.1002\/14651858.CD002290.pub6-BIB0098|cit98","doi-asserted-by":"crossref","first-page":"870","DOI":"10.1001\/jamapediatrics.2021.1068","article-title":"Inadequate dosage of mycophenolate mofetil is likely to yield substandard trial results and substandard patient care","volume":"175","author":"Angeletti","year":"2021","journal-title":"JAMA Pediatrics"},{"issue":"6","key":"10.1002\/14651858.CD002290.pub6-BIB0099|cit99","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1001\/jamapediatrics.2020.6150","article-title":"Rituximab vs low-dose mycophenolate mofetil in recurrence of steroid-dependent nephrotic syndrome in children and young adults: a randomized clinical trial","volume":"175","author":"Ravani","year":"2021","journal-title":"JAMA Pediatrics"},{"issue":"10","key":"10.1002\/14651858.CD002290.pub6-BIB0100|cit100","first-page":"2003","article-title":"Long-term efficacy of rituximab & MMF maintenance - therapy in childhood SDNS [abstract no: IPN11036-82]","volume":"34","author":"Basu","year":"2019","journal-title":"Pediatric Nephrology"},{"issue":"8","key":"10.1002\/14651858.CD002290.pub6-BIB0101|cit101","doi-asserted-by":"publisher","first-page":"1575-84","DOI":"10.1016\/j.ekir.2023.05.022","article-title":"Long-term efficacy and safety of rituximab versus tacrolimus in children with steroid dependent nephrotic syndrome","volume":"8","author":"Basu","year":"2023","journal-title":"KI Reports"},{"issue":"8","key":"10.1002\/14651858.CD002290.pub6-BIB0102|cit102","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1001\/jamapediatrics.2018.1323","article-title":"Efficacy of rituximab vs tacrolimus in pediatric corticosteroid-dependent nephrotic syndrome: a randomized clinical trial [Erratum in: JAMA Pediatr. 2018 Dec 1;172(12):1205]","volume":"172","author":"Basu","year":"2018","journal-title":"JAMA Pediatrics"},{"key":"10.1002\/14651858.CD002290.pub6-BIB0103|cit103","unstructured":"Schaefer F Superior efficacy of rituximab vs tacrolimus in pediatric steroid dependent nephrotic syndrome [abstract] 54th ERA-EDTA Congress; 2017 June 3-6; Madrid, Spain 2017"},{"issue":"9","key":"10.1002\/14651858.CD002290.pub6-BIB0104|cit104","doi-asserted-by":"crossref","first-page":"1591","DOI":"10.1007\/s00467-019-04251-5","article-title":"Randomized controlled trial on immunomodulatory effects of azithromycin in children with steroid-dependent nephrotic syndrome","volume":"34","author":"Sawires","year":"2019","journal-title":"Pediatric Nephrology"},{"issue":"10","key":"10.1002\/14651858.CD002290.pub6-BIB0105|cit105","first-page":"1933","article-title":"Randomized controlled trial on immunomodulatory effects of azithromycin in children with steroid dependent nephrotic syndrome [abstract no: IPN10189-90]","volume":"34","author":"Sawires","year":"2019","journal-title":"Pediatric Nephrology"},{"issue":"8","key":"10.1002\/14651858.CD002290.pub6-BIB0106|cit106","first-page":"1599","article-title":"Randomized trial comparing efficacy & safety of mycophenolate mofetil and levamisole in frequently relapsing & steroid dependent nephrotic syndrome [abstract no: P-SUN199]","volume":"28","author":"Bagga","year":"2013","journal-title":"Pediatric Nephrology"},{"issue":"12","key":"10.1002\/14651858.CD002290.pub6-BIB0107|cit107","first-page":"2434","article-title":"Randomized controlled trial to compare the efficacy and safety of mycophenolate mofetil versus levamisole in children with frequently relapsing and steroid dependent nephrotic syndrome [abstract]","volume":"29","author":"Sinha","year":"2015","journal-title":"Pediatric Nephrology"},{"issue":"1","key":"10.1002\/14651858.CD002290.pub6-BIB0108|cit108","doi-asserted-by":"crossref","first-page":"2010","DOI":"10.1016\/j.kint.2018.08.039","article-title":"Efficacy and safety of mycophenolate mofetil versus levamisole in frequently relapsing nephrotic syndrome: an open-label randomized controlled trial","volume":"95","author":"Sinha","year":"2019","journal-title":"Kidney International"},{"issue":"5","key":"10.1002\/14651858.CD002290.pub6-BIB0109|cit109","doi-asserted-by":"publisher","first-page":"1113-23","DOI":"10.1016\/j.kint.2024.01.028","article-title":"An open label non-inferiority randomized controlled trial evaluated alternate day prednisolone given daily during infections vs. levamisole in frequently relapsing nephrotic syndrome","volume":"105","author":"Sinha","year":"2024","journal-title":"Kidney International"},{"issue":"4 Suppl","key":"10.1002\/14651858.CD002290.pub6-BIB0110|cit110","doi-asserted-by":"crossref","first-page":"S200","DOI":"10.1016\/j.ekir.2021.03.488","article-title":"Efficacy and safety of prednisolone on alternate days made daily with infections versus levamisole in frequently relapsing nephrotic syndrome: an open label randomized controlled trial [abstract no: Pos-462]","volume":"6","author":"Sinha","year":"2021","journal-title":"Kidney International Reports"},{"issue":"10","key":"10.1002\/14651858.CD002290.pub6-BIB0111|cit111","doi-asserted-by":"crossref","first-page":"2171","DOI":"10.1007\/s00467-010-1518-x","article-title":"Alternate-day prednisolone made daily during infections versus levamisole for frequently-relapsing nephrotic syndrome [abstract no: IPN12086-88]","volume":"34","author":"Sinha","year":"2019","journal-title":"Pediatric Nephrology"},{"issue":"4","key":"10.1002\/14651858.CD002290.pub6-BIB0112|cit112","first-page":"241","article-title":"The efficacy and safety of rituximab in the treatment of steroid-dependent or frequently relapsing nephrotic syndrome in children","volume":"27","author":"Su","year":"2022","journal-title":"Hong Kong Journal of Paediatrics"},{"issue":"Program & Abstr","key":"10.1002\/14651858.CD002290.pub6-BIB0113|cit113","first-page":"126A","article-title":"Efficacy of levamisole compared to cyclophosphamide and steroid in frequently relapsing (FR) minimal change nephrotic syndrome (MCNS) [abstract no: A0660]","volume":"12","author":"Sural","year":"2001","journal-title":"Journal of the American Society of Nephrology"},{"key":"10.1002\/14651858.CD002290.pub6-BIB0114|cit114","first-page":"565","article-title":"Clinical evaluation of cyclosporin in the treatment of nephrotic syndrome: multicentre double-blind study","volume":"37","author":"Tohjoh","year":"1994","journal-title":"Jin Tohseki"},{"issue":"10","key":"10.1002\/14651858.CD002290.pub6-BIB0115|cit115","first-page":"1852","article-title":"Comparative efficacy of mycophenolate mofetil and cyclosporine in children with frequent relapse nephrotic syndrome [abstract no: PO-276]","volume":"31","author":"Uddin","year":"2016","journal-title":"Pediatric Nephrology"},{"issue":"10","key":"10.1002\/14651858.CD002290.pub6-BIB0116|cit116","doi-asserted-by":"crossref","first-page":"1147","DOI":"10.1136\/adc.65.10.1147","article-title":"Eight and 12 week courses of cyclophosphamide in nephrotic syndrome","volume":"65","author":"Ueda","year":"1990","journal-title":"Archives of Disease in Childhood"},{"issue":"1","key":"10.1002\/14651858.CD002290.pub6-BIB0117|cit117","doi-asserted-by":"crossref","first-page":"275","DOI":"10.5114\/aoms\/145587","article-title":"Comparison of rituximab, cyclophosphamide, and tacrolimus as first steroid-sparing agents for complicated relapsing\/steroid-dependent nephrotic syndrome in children: an evaluation of the health-related quality of life","volume":"18","author":"Wang","year":"2022","journal-title":"Archives of Medical Science"},{"key":"10.1002\/14651858.CD002290.pub6-BIB0118|cit118","unstructured":"Weiss R Results of a randomized, double-blind, placebo controlled, multi-center clinical trial of levamisole for the treatment of children with frequently relapsing or steroid dependent nephrotic syndrome Personal communication 2005"},{"issue":"Program & Abstr","key":"10.1002\/14651858.CD002290.pub6-BIB0119|cit119","first-page":"289","article-title":"Randomized, double-blind, placebo (P) controlled trial of levamisole (L) for children (CH) with frequently relapsing\/steroid dependant (FR\/SD) nephrotic syndrome (NS) [abstract no: 98P]","volume":"4","author":"Weiss","year":"1993","journal-title":"Journal of the American Society of Nephrology"},{"issue":"1","key":"10.1002\/14651858.CD002290.pub6-BIB0120|cit120","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1046\/j.1523-1755.2000.00168.x","article-title":"A multicenter trial of mizoribine compared with placebo in children with frequently relapsing nephrotic syndrome","volume":"58","author":"Yoshioka","year":"2000","journal-title":"Kidney International"},{"issue":"Program & Abstr","key":"10.1002\/14651858.CD002290.pub6-BIB0121|cit121","first-page":"163A","article-title":"Placebo-controlled trial of mizoribine (MZR) in children with frequently relapsing nephrotic syndrome (FRNS). The Pediatric Mizoribine Study Group [abstract]","volume":"9","author":"Yoshioka","year":"1998","journal-title":"Journal of the American Society of Nephrology"},{"issue":"4","key":"10.1002\/14651858.CD002290.pub6-BIB0122|cit122","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1007\/s00431-013-2192-3","article-title":"A prospective randomly controlled clinical trial on azithromycin therapy for induction treatment of children with nephrotic syndrome","volume":"173","author":"Zhang","year":"2014","journal-title":"European Journal of Pediatrics"},{"issue":"8","key":"10.1002\/14651858.CD002290.pub6-BIB0123|cit123","first-page":"1364","article-title":"A prospective clinical randomized controlled trial on azithromycin therapy in induction treatment in children with nephrotic syndrome [abstract no: O-44]","volume":"28","author":"Zhang","year":"2013","journal-title":"Pediatric Nephrology"},{"issue":"9","key":"10.1002\/14651858.CD002290.pub6-BIB0124|cit124","first-page":"1481","article-title":"Efficacy of zinc (Zn) in reducing relapses in steroid sensitive nephrotic syndrome (SSNS): double blind, randomized controlled trial (RCT) (CRG030600044) [abstract no: 184]","volume":"22","author":"Arun","year":"2007","journal-title":"Pediatric Nephrology"},{"issue":"8","key":"10.1002\/14651858.CD002290.pub6-BIB0125|cit125","doi-asserted-by":"crossref","first-page":"1583","DOI":"10.1007\/s00467-009-1170-5","article-title":"Efficacy of zinc supplements in reducing relapses in steroid-sensitive nephrotic syndrome","volume":"24","author":"Arun","year":"2009","journal-title":"Pediatric Nephrology"},{"key":"10.1002\/14651858.CD002290.pub6-BIB0126|cit126","article-title":"WITHDRAWN: Efficacy and safety of mycophenolate mofetil versus levamisole in children and adolescents with idiopathic nephrotic syndrome: results of a randomized clinical trial","volume":"-","author":"Basu","journal-title":"American Journal of Kidney Diseases"},{"issue":"8","key":"10.1002\/14651858.CD002290.pub6-BIB0127|cit127","first-page":"1353","article-title":"WITHDRAWN: Randomized controlled trial to compare the efficacy & safety of mycophenolate mofetil vs levamisole in children with frequent relapsing & steroid dependent nephrotic syndrome [abstract no: O-18]","volume":"28","author":"Basu","year":"2013","journal-title":"Pediatric Nephrology"},{"issue":"Suppl 3","key":"10.1002\/14651858.CD002290.pub6-BIB0128|cit128","first-page":"iii7","article-title":"WITHDRAWN: Efficacy and safety of mycophenolate-mofetil vs levamisole in children with idiopathic nephrotic syndrome: results of a randomized clinical trial [abstract]","volume":"29","author":"Basu","year":"2014","journal-title":"Nephrology Dialysis Transplantation"},{"issue":"Suppl 4","key":"10.1002\/14651858.CD002290.pub6-BIB0129|cit129","first-page":"65","article-title":"Effective and safe treatment of primary nephrotic syndrome with tacrolimus (FK 506) [abstract no: M207]","volume":"18","author":"Beige","year":"2003","journal-title":"Nephrology Dialysis Transplantation"},{"issue":"9","key":"10.1002\/14651858.CD002290.pub6-BIB0130|cit130","first-page":"C95","article-title":"Effect of omega-3 fatty acids on serum homocysteine in childhood steroid-sensitive nephrotic syndrome [abstract no: P011]","volume":"19","author":"Cerkauskiene","year":"2004","journal-title":"Pediatric Nephrology"},{"issue":"4","key":"10.1002\/14651858.CD002290.pub6-BIB0131|cit131","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1007\/s00467-008-1062-0","article-title":"Randomized cross-over trial comparing albumin and frusemide infusions in nephrotic syndrome","volume":"24","author":"Dharmaraj","year":"2009","journal-title":"Pediatric Nephrology"},{"key":"10.1002\/14651858.CD002290.pub6-BIB0132|cit132","unstructured":"Hari P Bagga A Does albumin infusion augment frusemide induced diuresis in edematous children with nephrotic syndrome? [abstract no: M-PO-0834] 4th World Congress of Nephrology.19th International Congress of the International Society of Nephrology (ISN); 2007 Apr 21-25; Rio de Janeiro, Brazil 2007 285"},{"issue":"Suppl 1","key":"10.1002\/14651858.CD002290.pub6-BIB0133|cit133","first-page":"S125","article-title":"Observation on refractory nephrotic syndrome with integrated traditional Chinese medicine (TCM) - Western medicine (WM) [abstract]","volume":"3","author":"Fong","year":"1997","journal-title":"Nephrology"},{"issue":"4","key":"10.1002\/14651858.CD002290.pub6-BIB0134|cit134","first-page":"441","article-title":"Effect of Triptergium wilfordii polyglycosidium on content of Th1 and Th2 in child recurrent nephrotic syndrome","volume":"33","author":"Hu","year":"2008","journal-title":"Zhongguo Zhongyao Zazhi [China Journal of Chinese Materia Medica]"},{"issue":"2","key":"10.1002\/14651858.CD002290.pub6-BIB0135|cit135","doi-asserted-by":"crossref","first-page":"57","DOI":"10.22442\/jlumhs.161520465","article-title":"Cyclosporine versus cyclophosphamide in childhood nephrotic syndrome","volume":"15","author":"Khemani","year":"2016","journal-title":"Journal of the Liaquat University of Medical & Health Sciences"},{"issue":"2","key":"10.1002\/14651858.CD002290.pub6-BIB0136|cit136","first-page":"240","article-title":"A controlled trial of levamisole in frequently relapsing minimal change disease [abstract]","volume":"26","author":"Kirubakaran","year":"1984","journal-title":"Kidney International"},{"issue":"4","key":"10.1002\/14651858.CD002290.pub6-BIB0137|cit137","first-page":"386","article-title":"Treatment of children with simple nephrotic syndrom using prednison once per day","volume":"15","author":"Li","year":"1994","journal-title":"Acta Academiae Medicinae Hubei"},{"key":"10.1002\/14651858.CD002290.pub6-BIB0138|cit138","first-page":"557A","article-title":"Mycophenolate mofetil therapy in primary nephrotic syndrome with hepatitis B virus infection [abstract no: F-PO1010]","volume":"16","author":"Li","year":"2005","journal-title":"Journal of the American Society of Nephrology"},{"issue":"10","key":"10.1002\/14651858.CD002290.pub6-BIB0139|cit139","doi-asserted-by":"crossref","first-page":"1616","DOI":"10.3109\/0886022X.2016.1172917","article-title":"Efficacy of leflunomide combined with prednisone in the treatment of refractory nephrotic syndrome","volume":"38","author":"Liu","year":"2016","journal-title":"Renal Failure"},{"key":"10.1002\/14651858.CD002290.pub6-BIB0140|cit140","first-page":"353A","article-title":"Randomized controlled trial of leflunomide in the treatment of refractory nephrotic syndrome [abstract]","volume":"15","author":"Lou","year":"2004","journal-title":"Journal of the American Society of Nephrology"},{"issue":"Abstracts Suppl","key":"10.1002\/14651858.CD002290.pub6-BIB0141|cit141","doi-asserted-by":"crossref","first-page":"766","DOI":"10.1681\/ASN.20223311S1766b","article-title":"Induction therapy with mycophenolate mofetil for steroid-sensitive nephrotic syndrome in children: a prospective single center pilot study [abstract no: SA-PO588]","volume":"33","author":"Mazo","year":"2022","journal-title":"Journal of the American Society of Nephrology"},{"issue":"1","key":"10.1002\/14651858.CD002290.pub6-BIB0142|cit142","first-page":"S125","article-title":"A clinical study on low dose cyclosporin A with diltiazem in the treatment of primary nephrotic syndrome [abstract no: P203]","volume":"3 Suppl","author":"Naigui","year":"1997","journal-title":"Nephrology"},{"key":"10.1002\/14651858.CD002290.pub6-BIB0143|cit143","unstructured":"Randomized trial comparing rituximab against mycophenolate mofetil in children wtih refractory nephrotic syndrome (RAMP) www.clinicaltrials.gov\/ct2\/show\/NCT02390362"},{"key":"10.1002\/14651858.CD002290.pub6-BIB0144|cit144","unstructured":"Part 1 - A clinical trial in patients with frequently relapsing and steroid-dependent nephrotic syndrome clinicaltrials.gov\/show\/NCT05599815"},{"key":"10.1002\/14651858.CD002290.pub6-BIB0145|cit145","unstructured":"A study to evaluate the efficacy and safety of obinutuzumab versus MMF in participants with childhood onset idiopathic nephrotic syndrome (INShore) clinicaltrials.gov\/show\/NCT05627557"},{"issue":"Nov","key":"10.1002\/14651858.CD002290.pub6-BIB0146|cit146","first-page":"524A","article-title":"A controlled, prospective study of efficacy of leflunomide in patients with nephrotic syndrome [abstract no: SA-PO1025]","volume":"14","author":"Ni","year":"2003","journal-title":"Journal of the American Society of Nephrology"},{"issue":"Suppl 1","key":"10.1002\/14651858.CD002290.pub6-BIB0147|cit147","first-page":"S130","article-title":"Effect of combined treatment with methylprednisolone pulse and nafamostat mesilate for nephrotic syndrome [abstract no: P221]","volume":"3","author":"Nishiyama","year":"1997","journal-title":"Nephrology"},{"issue":"Suppl 5","key":"10.1002\/14651858.CD002290.pub6-BIB0148|cit148","first-page":"v230","article-title":"Therapy of first episode steroid responsive nephrotic syndrome (FESRNS): a randomised controlled trial [abstract no: MP087]","volume":"20","author":"Pecoraro","year":"2005","journal-title":"Nephrology Dialysis Transplantation"},{"issue":"9","key":"10.1002\/14651858.CD002290.pub6-BIB0149|cit149","first-page":"C72","article-title":"Therapy of first episode of steroid responsive nephrotic syndrome: a randomised controlled trial [abstract no: OFC41]","volume":"19","author":"Pecoraro","year":"2004","journal-title":"Pediatric Nephrology"},{"issue":"Suppl 4","key":"10.1002\/14651858.CD002290.pub6-BIB0150|cit150","first-page":"63","article-title":"Therapy of first episode of steroid responsive nephrotic syndrome: a randomised controlled trial [abstract no: M199]","volume":"18","author":"Pecoraro","year":"2003","journal-title":"Nephrology Dialysis Transplantation"},{"issue":"9","key":"10.1002\/14651858.CD002290.pub6-BIB0151|cit151","doi-asserted-by":"crossref","first-page":"e037306","DOI":"10.1136\/bmjopen-2020-037306","article-title":"Efficacy and safety of intravenous immunoglobulin with rituximab versus rituximab alone in childhood-onset steroid-dependent and frequently relapsing nephrotic syndrome: protocol for a multicentre randomised controlled trial","volume":"10","author":"Hogan","year":"2020","journal-title":"BMJ Open"},{"issue":"1","key":"10.1002\/14651858.CD002290.pub6-BIB0152|cit152","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1007\/BF00858434","article-title":"Intravenous immunoglobulin in minimal change nephrotic syndrome: a crossover trial","volume":"4","author":"Rowe","year":"1990","journal-title":"Pediatric Nephrology"},{"issue":"2","key":"10.1002\/14651858.CD002290.pub6-BIB0153|cit153","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1089\/109662002760178177","article-title":"Hypocholesterolemic effect of spirulina in patients with hyperlipidemic nephrotic syndrome","volume":"5","author":"Samuels","year":"2002","journal-title":"Journal of Medicinal Food"},{"key":"10.1002\/14651858.CD002290.pub6-BIB0154|cit154","unstructured":"Sancewicz-Pach K Slowiaczek E Kwinta-Rybicka J Wilkosz K Nowak J Results for 8-week and 12-month cyclosporin A treatment in children with primary nephrotic syndrome [abstract] XIIIth International Congress of Nephrology; 1995 Jul 2-6; Madrid, Spain 1995 270"},{"issue":"3","key":"10.1002\/14651858.CD002290.pub6-BIB0155|cit155","first-page":"127","article-title":"Comparison of the effectiveness of cyclophosphamide and cytembena in controlled clinical trial in nephrotic syndrome and chronic glomerulonephritis","volume":"31","author":"Sasinka","year":"1976","journal-title":"Ceskoslovenska Pediatrie"},{"issue":"9","key":"10.1002\/14651858.CD002290.pub6-BIB0156|cit156","first-page":"C105","article-title":"Spirulina supplementation in pediatric nephrotic syndrome [abstract no: P051]","volume":"19","author":"Shendurnikar","year":"2004","journal-title":"Pediatric Nephrology"},{"key":"10.1002\/14651858.CD002290.pub6-BIB0157|cit157","unstructured":"Stavrovskaya E Neverov N Shvetsov M Tareeva I Angiotensin-converting enzyme inhibitors (ACEI) and angiotensin 2 receptor blockers (ARB) attenuate hypercholesterolemia in patients with chronic nephrotic glomerulonephritis [abstract] 38th Congress of the European Renal Association European Dialysis & Transplant Association; 2001 Jun 24-27; Vienna, Austria 2001 96"},{"issue":"3 Suppl 4","key":"10.1002\/14651858.CD002290.pub6-BIB0158|cit158","first-page":"262","article-title":"A randomized trial of cyclosporine with low-dose prednisone compared with high-dose prednisone in nephrotic syndrome","volume":"20","author":"Tejani","year":"1988","journal-title":"Transplantation Proceedings"},{"issue":"1","key":"10.1002\/14651858.CD002290.pub6-BIB0159|cit159","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1159\/000186526","article-title":"A randomized controlled trial of low-dose prednisone and ciclosporin versus high-dose prednisone in nephrotic syndrome of children","volume":"59","author":"Tejani","year":"1991","journal-title":"Nephron"},{"issue":"1","key":"10.1002\/14651858.CD002290.pub6-BIB0160|cit160","first-page":"213","article-title":"Randomized trial of cylosporine and low dose prednisone (P&CS) vs conventional prednisone (P) therapy in recent onset (< 1 yr) nephrotic syndrome (NS) [abstract]","volume":"35","author":"Tejani","year":"1989","journal-title":"Kidney International"},{"issue":"5","key":"10.1002\/14651858.CD002290.pub6-BIB0161|cit161","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1136\/adc.53.5.430","article-title":"Controlled trial of disodium cromoglycate in prevention of relapse of steroid-responsive nephrotic syndrome of childhood","volume":"53","author":"Trompeter","year":"1978","journal-title":"Archives of Disease in Childhood"},{"issue":"2","key":"10.1002\/14651858.CD002290.pub6-BIB0162|cit162","first-page":"82","article-title":"Therapeutic trial with levamisole in children with idiopathic minimal change nephrotic syndrome","volume":"40","author":"Urdaneta Carruyo","year":"1983","journal-title":"Boletin Medico del Hospital Infantil de Mexico"},{"issue":"7","key":"10.1002\/14651858.CD002290.pub6-BIB0163|cit163","doi-asserted-by":"crossref","first-page":"682","DOI":"10.1631\/jzus.2005.B0682","article-title":"The treatment of relapsing primary nephrotic syndrome in children","volume":"Science. B. 6","author":"Wang","year":"2005","journal-title":"Journal of Zhejiang University"},{"issue":"1","key":"10.1002\/14651858.CD002290.pub6-BIB0164|cit164","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1111\/nep.12351","article-title":"Triple immunosuppressive therapy in steroid-resistant nephrotic syndrome children with tacrolimus resistance or tacrolimus sensitivity but frequently relapsing","volume":"20","author":"Wu","year":"2015","journal-title":"Nephrology"},{"issue":"3","key":"10.1002\/14651858.CD002290.pub6-BIB0165|cit165","doi-asserted-by":"crossref","first-page":"153","DOI":"10.2739\/kurumemedj.18.153","article-title":"Evaluation of alternate-day steroid therapy for nephrotic syndrome in childhood by cross-over study","volume":"18","author":"Yamashita","year":"1971","journal-title":"Kurume Medical Journal"},{"issue":"5","key":"10.1002\/14651858.CD002290.pub6-BIB0166|cit166","first-page":"575","article-title":"A prospective multicenter clinical control trial on treatment of refractory nephrotic syndrome with mycophenolate mofetil in children","volume":"10","author":"Yi","year":"2008","journal-title":"Zhongguo Dangdai Erke Zazhi"},{"issue":"4","key":"10.1002\/14651858.CD002290.pub6-BIB0167|cit167","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1007\/s40620-016-0297-2","article-title":"Montelukast as an add-on treatment in steroid dependant nephrotic syndrome, randomised-controlled trial","volume":"29","author":"Zedan","year":"2016","journal-title":"Journal of Nephrology"},{"issue":"9","key":"10.1002\/14651858.CD002290.pub6-BIB0168|cit168","first-page":"1609","article-title":"Prospective clinical randomized controlled trial of pulse methylprednisolone therapy in children with steroid sensitive nephrotic syndrome [abstract no: 797]","volume":"22","author":"Zhang","year":"2007","journal-title":"Pediatric Nephrology"},{"issue":"9","key":"10.1002\/14651858.CD002290.pub6-BIB0169|cit169","first-page":"C97","article-title":"Effect of the astragalus injection on urine protein in children nephrotic syndrome [abstract]","volume":"19","author":"Zhi-Hong","year":"2004","journal-title":"Pediatric Nephrology"},{"issue":"5","key":"10.1002\/14651858.CD002290.pub6-BIB0170|cit170","first-page":"682","article-title":"Therapeutic effect of Ginkgo biloba leaf extract on hypercholestrolemia in children with nephrotic syndrome","volume":"27","author":"Zhong","year":"2007","journal-title":"Nanfang Yeie Daxue Xuebao [Journal of Southern Medical University]"},{"issue":"8","key":"10.1002\/14651858.CD002290.pub6-BIB0171|cit171","first-page":"1419","article-title":"A study of leflunomide in treatment of juvenile refractory nephropathy syndrome [abstract no: P-SUN179]","volume":"28","author":"Zhu","year":"2013","journal-title":"Pediatric Nephrology"},{"issue":"Suppl 1","key":"10.1002\/14651858.CD002290.pub6-BIB0172|cit172","first-page":"S124","article-title":"Mechanism that Chinese traditional medicine reduces relapses of idiopathic nephrotic syndrome (INS) in children [abstract no: P198]","volume":"3","author":"Zou","year":"1997","journal-title":"Nephrology"},{"issue":"7","key":"10.1002\/14651858.CD002290.pub6-BIB0173|cit173","first-page":"S64-5","article-title":"To study the efficacy of rituximab in frequently relapsing\/steroid dependent nephrotic syndrome [abstract no: 87]","volume":"32","author":"Gaude","year":"2022","journal-title":"Indian Journal of Nephrology"},{"issue":"2","key":"10.1002\/14651858.CD002290.pub6-BIB0174|cit174","doi-asserted-by":"publisher","first-page":"82","DOI":"10.4103\/AJPN.AJPN_10_19","article-title":"Mycophenolate mofetil for maintenance of remission in children with steroid\u2011 and calcineurin inhibitor\u2011 dependent nephrotic syndrome: a prospective, randomized multicenter trial","volume":"2","author":"Yang","year":"2019","journal-title":"Asian Journal of Pediatric Neprology"},{"issue":"6","key":"10.1002\/14651858.CD002290.pub6-BIB0175|cit175","doi-asserted-by":"publisher","first-page":"606-11","DOI":"10.7499\/j.issn.1008-8830.2301026","article-title":"Efficacy and safety of low-dose rituximab in treatment of pediatric nephrotic syndrome: a prospective randomized controlled trial","volume":"25","author":"Zhu","year":"2023","journal-title":"Zhongguo Dangdai Erke Zazhi [Chinese Journal of Contemporary Pediatrics]"},{"key":"10.1002\/14651858.CD002290.pub6-BIB0176|cit176","unstructured":"A study to evaluate the efficacy and safety of obinutuzumab versus MMF in participants with childhood onset idiopathic nephrotic syndrome https:\/\/trialsearch.who.int\/Trial2.aspx?TrialID=CTIS2023-505140-19-00 2024"},{"key":"10.1002\/14651858.CD002290.pub6-BIB0177|cit177","unstructured":"A clinical trial to study the efficacy of daily versus every-other day levamisole therapy in children with frequently relapsing nephrotic syndrome trialsearch.who.int\/Trial2.aspx?TrialID=CTRI\/2022\/01\/039125"},{"key":"10.1002\/14651858.CD002290.pub6-BIB0178|cit178","unstructured":"Azithromycin in paediatric nephrotic syndrome trialsearch.who.int\/Trial2.aspx?TrialID=CTRI\/2022\/01\/039753"},{"key":"10.1002\/14651858.CD002290.pub6-BIB0179|cit179","unstructured":"Rituximab maintenance therapy in nephrotic syndrome trialsearch.who.int\/Trial2.aspx?TrialID=CTRI\/2022\/02\/040186"},{"key":"10.1002\/14651858.CD002290.pub6-BIB0180|cit180","unstructured":"Study comparing the ability of two medications, namely oral tablets of mycophenolate mofetil and cyclophosphamide, in keeping disease well controlled in patients with frequently relapsing or steroid dependent nephrotic syndrome trialsearch.who.int\/Trial2.aspx?TrialID=CTRI\/2022\/10\/046891"},{"key":"10.1002\/14651858.CD002290.pub6-BIB0181|cit181","unstructured":"Comparison of a levamisole drug use in two different durations and dose in treatment of frequently relapsing nephrotic syndrome trialsearch.who.int\/Trial2.aspx?TrialID=CTRI\/2022\/12\/048452"},{"key":"10.1002\/14651858.CD002290.pub6-BIB0182|cit182","unstructured":"A study to compare two medicines, mycophenolate mofetil and tacrolimus, to see which one works better in helping children with kidney problems called nephrotic syndrome stay healthy and not get sick again too often trialsearch.who.int\/Trial2.aspx?TrialID=CTRI\/2023\/09\/058171 2023"},{"key":"10.1002\/14651858.CD002290.pub6-BIB0183|cit183","unstructured":"Study to determine whether two drugs are better than one in treatment of difficult to treat nephrotic syndrome trialsearch.who.int\/Trial2.aspx?TrialID=CTRI\/2024\/04\/065552 2024"},{"key":"10.1002\/14651858.CD002290.pub6-BIB0184|cit184","unstructured":"Efficacy and safety of levamisole in African children with nephrotic syndrome: a protocol for a double-blinded, standard of care-controlled randomized trial (ESOLAC Trial) trialsearch.who.int\/Trial2.aspx?TrialID=PACTR202201750782433"},{"key":"10.1002\/14651858.CD002290.pub6-BIB0185|cit185","unstructured":"Early rituximab treatment in children with idiopathic nephrotic syndrome Eng. ERICONS - Early RITUXIMAB in Childhood Onset Nephrotic Syndrome trialsearch.who.int\/Trial2.aspx?TrialID=EUCTR2020-004982-37-PL"},{"issue":"1","key":"10.1002\/14651858.CD002290.pub6-BIB0186|cit186","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1186\/s12882-018-1033-z","article-title":"Study protocol: high-dose mizoribine with prednisolone therapy in short-term relapsing steroid-sensitive nephrotic syndrome to prevent frequent relapse (JSKDC05 trial)","volume":"19","author":"Hama","year":"2018","journal-title":"BMC Nephrology"},{"issue":"9","key":"10.1002\/14651858.CD002290.pub6-BIB0187|cit187","first-page":"1740","article-title":"Protocol of an open, randomized, controlled, multicenter trial on the initial treatment of idiopathic steroid-sensitive nephrotic syndrome in children with mycophenolate mofetil vs. prednisone: the Intent Study [abstract no: P176]","volume":"29","author":"Benz","year":"2014","journal-title":"Pediatric Nephrology"},{"issue":"10","key":"10.1002\/14651858.CD002290.pub6-BIB0188|cit188","doi-asserted-by":"crossref","first-page":"e024882","DOI":"10.1136\/bmjopen-2018-024882","article-title":"Initial treatment of steroid-sensitive idiopathic nephrotic syndrome in children with mycophenolate mofetil versus prednisone: protocol for a randomised, controlled, multicentre trial (INTENT study)","volume":"8","author":"Ehren","year":"2018","journal-title":"BMJ Open"},{"key":"10.1002\/14651858.CD002290.pub6-BIB0189|cit189","unstructured":"Tonshoff B Initial treatment of idiopathic nephrotic syndrome in children with mycophenolate mofetil vs. prednisone: a randomized, controlled, multicenter study (INTENT Study): Clinical study protocol: Version 4.0\/20150325 www.intent-study.de\/.cm4all\/iproc.php\/Studienprotokoll_INTENT_V4_2015_03_25_signiert.pdf?cdp=a"},{"issue":"1","key":"10.1002\/14651858.CD002290.pub6-BIB0190|cit190","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1186\/s12882-019-1470-3","article-title":"Study protocol: multicenter double-blind, randomized, placebo-controlled trial of rituximab for the treatment of childhood-onset early-stage uncomplicated frequently relapsing or steroid-dependent nephrotic syndrome (JSKDC10 trial)","volume":"20","author":"Nagano","year":"2019","journal-title":"BMC Nephrology"},{"issue":"8","key":"10.1002\/14651858.CD002290.pub6-BIB0191|cit191","doi-asserted-by":"crossref","first-page":"e027011","DOI":"10.1136\/bmjopen-2018-027011","article-title":"Prevention of relapses with levamisole as adjuvant therapy in children with a first episode of idiopathic nephrotic syndrome: study protocol for a double blind, randomised placebo-controlled trial (the LEARNS study)","volume":"9","author":"Veltkamp","year":"2019","journal-title":"BMJ Open"},{"issue":"10","key":"10.1002\/14651858.CD002290.pub6-BIB0192|cit192","first-page":"1938","article-title":"Prevention of relapses with levamisole as adjuvant therapy to corticosteroids in children with a first episode of idiopathic nephrotic syndrome \u2013 an international, double blind, placebo-controlled randomized trial [abstract no: O-327]","volume":"33","author":"Veltkamp","year":"2018","journal-title":"Pediatric Nephrology"},{"issue":"11","key":"10.1002\/14651858.CD002290.pub6-BIB0193|cit193","doi-asserted-by":"crossref","first-page":"e052450","DOI":"10.1136\/bmjopen-2021-052450","article-title":"Randomised controlled trial comparing rituximab to mycophenolate mofetil in children and young adults with steroid dependent idiopathic nephrotic syndrome: study protocol","volume":"11","author":"Lugani","year":"2021","journal-title":"BMJ Open"},{"key":"10.1002\/14651858.CD002290.pub6-BIB0194|cit194","unstructured":"Availability study of ACTH to treat children SRNS\/SDNS clinicaltrials.gov\/show\/NCT02972346"},{"key":"10.1002\/14651858.CD002290.pub6-BIB0195|cit195","unstructured":"Study of tacrolimus vs mycophenolate mofetil in pediatric patients with nephrotic syndrome (STAMP) clinicaltrials.gov\/show\/NCT04048161"},{"key":"10.1002\/14651858.CD002290.pub6-BIB0196|cit196","unstructured":"Efficacy and safety of obinutuzumab versus rituximab in childhood steroid dependant and frequent relapsing nephrotic syndrome clinicaltrials.gov\/show\/NCT05786768 2023"},{"key":"10.1002\/14651858.CD002290.pub6-BIB0197|cit197","unstructured":"Efficacy and safety of rituximab versus mycophenolate mofetil in children with steroid-dependent nephrotic syndrome clinicaltrials.gov\/ct2\/show\/NCT05843968 2023"},{"key":"10.1002\/14651858.CD002290.pub6-BIB0198|cit198","unstructured":"Clinical study of rituximab for the treatment for idiopathic membranous nephropathy with nephrotic syndrome (PRIME) clinicaltrials.gov\/study\/NCT05914155 2023"},{"key":"10.1002\/14651858.CD002290.pub6-BIB0199|cit199","unstructured":"Study of adrenocorticotropic hormone on children with frequent relapse or steroid-dependent nephrotic syndrome: a prospective, multicenter, randomized, open-label clinical trial clinicaltrials.gov\/ct2\/show\/NCT06079788 2023"},{"issue":"1","key":"10.1002\/14651858.CD002290.pub6-BIB0200|cit200","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1186\/s12882-020-02153-5","article-title":"Randomized clinical trial to compare efficacy and safety of repeated courses of rituximab to single-course rituximab followed by maintenance mycophenolate-mofetil in children with steroid dependent nephrotic syndrome","volume":"21","author":"Basu","year":"2020","journal-title":"BMC Nephrology"},{"key":"10.1002\/14651858.CD002290.pub6-BIB0201|cit201","unstructured":"A multi-center randomized controlled trial of tacrolimus versus cyclosporine for frequently relapsing nephrotic syndrome in children (JSKDC06) trialsearch.who.int\/Trial2.aspx?TrialID=JPRN-UMIN000004204"},{"issue":"7212","key":"10.1002\/14651858.CD002290.pub6-BIB0202|cit202","doi-asserted-by":"crossref","first-page":"1103","DOI":"10.1016\/S0140-6736(61)91026-1","article-title":"164 children with nephrosis","volume":"2","author":"Arneil","year":"1961","journal-title":"Lancet"},{"issue":"2","key":"10.1002\/14651858.CD002290.pub6-BIB0203|cit203","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1016\/j.kint.2019.09.033","article-title":"Both the rituximab dose and maintenance immunosuppression in steroid-dependent\/frequently-relapsing nephrotic syndrome have important effects on outcomes","volume":"97","author":"Webb","year":"2020","journal-title":"Kidney International"},{"issue":"6","key":"10.1002\/14651858.CD002290.pub6-BIB0204|cit204","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1136\/adc.85.6.478","article-title":"De novo malignancy after paediatric renal replacement therapy","volume":"85","author":"Coutinho","year":"2001","journal-title":"Archives of Disease in Childhood"},{"issue":"1","key":"10.1002\/14651858.CD002290.pub6-BIB0205|cit205","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD000164.pub2","article-title":"Phenobarbital prior to preterm birth for preventing neonatal periventricular haemorrhage","author":"Crowther","year":"2010","journal-title":"Cochrane Database of Systematic Reviews"},{"issue":"8","key":"10.1002\/14651858.CD002290.pub6-BIB0206|cit206","doi-asserted-by":"crossref","first-page":"1241","DOI":"10.1007\/s00467-011-1851-8","article-title":"Nephrotic syndrome in The Netherlands: a population-based cohort study and a review of the literature","volume":"26","author":"El Bakkali","year":"2011","journal-title":"Pediatric Nephrology"},{"issue":"7750","key":"10.1002\/14651858.CD002290.pub6-BIB0207|cit207","doi-asserted-by":"crossref","first-page":"568","DOI":"10.1016\/S0140-6736(72)90358-3","article-title":"Sterility and testicular atrophy related to cyclophosphamide therapy","volume":"1","author":"Fairley","year":"1972","journal-title":"Lancet"},{"key":"10.1002\/14651858.CD002290.pub6-BIB0208|cit208","unstructured":"Idiopathic nephrotic syndrome in children. National protocol for diagnosis and treatment for a rare disease www.has-sante.fr\/portail\/upload\/docs\/application\/pdf\/2008-06\/pnds_sni_enfant.pdf"},{"issue":"2","key":"10.1002\/14651858.CD002290.pub6-BIB0209|cit209","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1542\/peds.2008-1559","article-title":"Management of childhood onset nephrotic syndrome","volume":"124","author":"Gipson","year":"2009","journal-title":"Pediatrics"},{"issue":"7650","key":"10.1002\/14651858.CD002290.pub6-BIB0210|cit210","doi-asserted-by":"crossref","first-page":"924","DOI":"10.1136\/bmj.39489.470347.AD","article-title":"GRADE: an emerging consensus on rating quality of evidence and strength of recommendations","volume":"336","author":"Guyatt","year":"2008","journal-title":"BMJ"},{"issue":"4","key":"10.1002\/14651858.CD002290.pub6-BIB0211|cit211","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1016\/j.jclinepi.2010.04.026","article-title":"GRADE guidelines: 1. Introduction-GRADE evidence profiles and summary of findings tables","volume":"64","author":"Guyatt","year":"2011","journal-title":"Journal of Clinical Epidemiology"},{"issue":"8","key":"10.1002\/14651858.CD002290.pub6-BIB0212|cit212","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD001533.pub7","article-title":"Corticosteroid therapy for nephrotic syndrome in children","author":"Hahn","year":"2024","journal-title":"Cochrane Database of Systematic Reviews"},{"issue":"7414","key":"10.1002\/14651858.CD002290.pub6-BIB0213|cit213","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1136\/bmj.327.7414.557","article-title":"Measuring inconsistency in meta-analyses","volume":"327","author":"Higgins","year":"2003","journal-title":"BMJ"},{"key":"10.1002\/14651858.CD002290.pub6-BIB0214|cit214","unstructured":"Higgins JP Thomas J Chandler J Cumpston M Li T Page MJ Cochrane Handbook for Systematic Reviews of Interventions version 6.3 (updated February 2022). Cochrane, 2022 Available from www.training.cochrane.org\/handbook"},{"issue":"Suppl 4","key":"10.1002\/14651858.CD002290.pub6-BIB0215|cit215","first-page":"261","article-title":"Multicenter trial of mycophenolate mofetil (MMF) in children with steroid dependent (SD) or frequent relapsing (FR) nephrotic syndrome (NS). Report of the Southwest Pediatric Nephrology Study Group [abstract]","volume":"18","author":"Hogg","year":"2003","journal-title":"Nephrology Dialysis Transplantation"},{"issue":"3","key":"10.1002\/14651858.CD002290.pub6-BIB0216|cit216","doi-asserted-by":"crossref","first-page":"877","DOI":"10.1007\/s00467-022-05739-3","article-title":"IPNA clinical practice recommendations for the diagnosis and management of children with steroid-sensitive nephrotic syndrome","volume":"38","author":"Trautmann","year":"2023","journal-title":"Pediatric Nephrology"},{"issue":"5","key":"10.1002\/14651858.CD002290.pub6-BIB0217|cit217","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1007\/s13312-021-2217-3","article-title":"Steroid sensitive nephrotic syndrome: revised guidelines","volume":"58","author":"Sinha","year":"2021","journal-title":"Indian Pediatrics"},{"issue":"2","key":"10.1002\/14651858.CD002290.pub6-BIB0218|cit218","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1038\/ki.1978.23","article-title":"Nephrotic syndrome in children: prediction of histopathology from clinical and laboratory characteristics at time of diagnosis. A report of the International Study of Kidney Disease in Children","volume":"13","year":"1978","journal-title":"Kidney International"},{"issue":"3","key":"10.1002\/14651858.CD002290.pub6-BIB0219|cit219","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1007\/s10157-015-1216-x","article-title":"Evidence-based clinical practice guidelines for nephrotic syndrome 2014","volume":"20","author":"Nishi","year":"2014","journal-title":"Clinical & Experimental Nephrology"},{"issue":"4S","key":"10.1002\/14651858.CD002290.pub6-BIB0220|cit220","first-page":"S1\u2013276","article-title":"KDIGO 2021 clinical practice guideline for the management of glomerular diseases","volume":"100","author":"Improving Global Outcomes (KDIGO) Glomerular Diseases Work Group","year":"2021","journal-title":"Kidney International"},{"issue":"5","key":"10.1002\/14651858.CD002290.pub6-BIB0221|cit221","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1056\/NEJM200102013440517","article-title":"Transmission of glomerular permeability factor from a mother to her child","volume":"344","author":"Kemper","year":"2001","journal-title":"New England Journal of Medicine"},{"issue":"7","key":"10.1002\/14651858.CD002290.pub6-BIB0222|cit222","doi-asserted-by":"crossref","first-page":"544","DOI":"10.1136\/adc.57.7.544","article-title":"Long-term outcome of primary nephrotic syndrome","volume":"57","author":"Koskimies","year":"1982","journal-title":"Archives of Disease in Childhood"},{"issue":"12","key":"10.1002\/14651858.CD002290.pub6-BIB0223|cit223","doi-asserted-by":"crossref","first-page":"1040","DOI":"10.1007\/s004670100021","article-title":"Time trends and ethnic patterns of childhood nephrotic syndrome in Yorkshire, UK","volume":"16","author":"McKinney","year":"2001","journal-title":"Pediatric Nephrology"},{"issue":"9128","key":"10.1002\/14651858.CD002290.pub6-BIB0224|cit224","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1016\/S0140-6736(98)01085-X","article-title":"Does quality of reports of randomised trials affect estimates of intervention efficacy reported in meta-analyses?","volume":"352","author":"Moher","year":"1998","journal-title":"Lancet"},{"issue":"10143","key":"10.1002\/14651858.CD002290.pub6-BIB0225|cit225","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/S0140-6736(18)30536-1","article-title":"Idiopathic nephrotic syndrome in children","volume":"392","author":"Noone","year":"2018","journal-title":"Lancet"},{"issue":"7790","key":"10.1002\/14651858.CD002290.pub6-BIB0226|cit226","first-page":"1290","article-title":"Cyclophosphamide therapy and sterility","volume":"2","author":"Queshi","journal-title":"Lancet"},{"issue":"7794","key":"10.1002\/14651858.CD002290.pub6-BIB0227|cit227","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1016\/S0140-6736(73)90491-1","article-title":"Cyclophosphamide and the pubertal testis","volume":"1","author":"Rapola","year":"1973","journal-title":"Lancet"},{"issue":"14","key":"10.1002\/14651858.CD002290.pub6-BIB0228|cit228","doi-asserted-by":"crossref","first-page":"878","DOI":"10.1056\/NEJM199604043341402","article-title":"Circulating factor associated with increased glomerular permeability to albumin in recurrent focal segmental glomerulosclerosis","volume":"354","author":"Savin","year":"1996","journal-title":"New England Journal of Medicine"},{"issue":"6","key":"10.1002\/14651858.CD002290.pub6-BIB0229|cit229","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1001\/archpedi.1968.02100020627009","article-title":"The nephrotic syndrome: its incidence and implications for the community","volume":"116","author":"Schlesinger","year":"1968","journal-title":"American Journal of Diseases of Children"},{"issue":"5","key":"10.1002\/14651858.CD002290.pub6-BIB0230|cit230","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1001\/jama.1995.03520290060030","article-title":"Empirical evidence of bias. Dimensions of methodological quality associated with estimates of treatment effects in controlled trials","volume":"273","author":"Schulz","year":"1995","journal-title":"JAMA"},{"key":"10.1002\/14651858.CD002290.pub6-BIB0231|cit231","unstructured":"Sch\u00fcnemann HJ Higgins JP Vist GE Glasziou P Akl EA Skoetz N Chapter 14: Completing \u2018Summary of findings\u2019 tables and grading the certainty of the evidence. In: Higgins JP, Thomas J, Chandler J, Cumpston M, Li T, Page MJ, Welch VA (editors). Cochrane Handbook for Systematic Reviews of Interventions version 6.3 (updated February 2022). Cochrane, 2022 Available from www.training.cochrane.org\/handbook"},{"key":"10.1002\/14651858.CD002290.pub6-BIB0232|cit232","unstructured":"Sch\u00fcnemann HJ Vist GE Higgins JP Santesso N Deeks JJ Glasziou P Chapter 15: Interpreting results and drawing conclusions. In: Higgins JP, Thomas J, Chandler J, Cumpston M, Li T, Page MJ, Welch VA (editors). Cochrane Handbook for Systematic Reviews of Interventions version 6.3 (updated February 2022). Cochrane, 2022 Available from www.training.cochrane.org\/handbook"},{"issue":"1","key":"10.1002\/14651858.CD002290.pub6-BIB0233|cit233","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1186\/s13052-017-0356-x","article-title":"The Italian Society for Pediatric Nephrology (SINePe) consensus document on the management of nephrotic syndrome in children: Part I - Diagnosis and treatment of the first episode and the first relapse","volume":"43","author":"Pasini","year":"2017","journal-title":"Italian Journal of Pediatrics"},{"issue":"7","key":"10.1002\/14651858.CD002290.pub6-BIB0234|cit234","doi-asserted-by":"crossref","first-page":"1848","DOI":"10.1093\/ndt\/gfi274","article-title":"Treatment of severe steroid-dependent nephrotic syndrome (SDNS) in children with tacrolimus","volume":"21","author":"Sinha","year":"2006","journal-title":"Nephrology Dialysis Transplantation"},{"issue":"4","key":"10.1002\/14651858.CD002290.pub6-BIB0235|cit235","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1093\/ndt\/gfac228","article-title":"Sequential rituximab therapy sustains remission of nephrotic syndrome but carries high risk of adverse effects","volume":"38","author":"Sinha","year":"2023","journal-title":"Nephrology Dialysis Transplantation"},{"issue":"6","key":"10.1002\/14651858.CD002290.pub6-BIB0236|cit236","doi-asserted-by":"crossref","first-page":"1039","DOI":"10.1007\/s00467-013-2736-9","article-title":"Predictors of remission and relapse in idiopathic nephrotic syndrome: a prospective cohort study","volume":"29","author":"Sureshkumar","year":"2014","journal-title":"Pediatric Nephrology"},{"issue":"5","key":"10.1002\/14651858.CD002290.pub6-BIB0237|cit237","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1681\/ASN.V85769","article-title":"Prognostic significance of the early course of minimal change nephrotic syndrome: report of the International Study of Kidney Disease in Children","volume":"8","author":"Tarshish","year":"1997","journal-title":"Journal of the American Society of Nephrology"},{"issue":"11","key":"10.1002\/14651858.CD002290.pub6-BIB0238|cit238","doi-asserted-by":"crossref","first-page":"2073","DOI":"10.1007\/s00467-012-2228-3","article-title":"Treatment of tacrolimus or cyclosporine A in children with idiopathic nephrotic syndrome","volume":"27","author":"Wang","year":"2012","journal-title":"Pediatric Nephrology"},{"issue":"5","key":"10.1002\/14651858.CD002290.pub6-BIB0239|cit239","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1111\/j.1440-1754.2007.01077.x","article-title":"Idiopathic nephrotic syndrome in New Zealand children, demographic, clinical features, initial management and outcome after twelve-month follow-up: results of a three-year national surveillance study","volume":"43","author":"Wong","year":"2007","journal-title":"Journal of Paediatrics & Child Health"},{"issue":"1","key":"10.1002\/14651858.CD002290.pub6-BIB0240|cit240","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD002290","article-title":"Non-corticosteroid treatment for nephrotic syndrome in children","author":"Durkan","year":"2000","journal-title":"Cochrane Database of Systematic Reviews"},{"issue":"4","key":"10.1002\/14651858.CD002290.pub6-BIB0241|cit241","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD002290","article-title":"Non-corticosteroid treatment for nephrotic syndrome in children","author":"Durkan","year":"2001","journal-title":"Cochrane Database of Systematic Reviews"},{"issue":"5","key":"10.1002\/14651858.CD002290.pub6-BIB0242|cit242","doi-asserted-by":"crossref","first-page":"1919","DOI":"10.1046\/j.1523-1755.2001.0590051919.x","article-title":"Immunosuppressive agents in childhood nephrotic syndrome: a meta-analysis of randomized controlled trials","volume":"59","author":"Durkan","year":"2001","journal-title":"Kidney International"},{"issue":"2","key":"10.1002\/14651858.CD002290.pub6-BIB0243|cit243","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD002290.pub2","article-title":"Non-corticosteroid treatment for nephrotic syndrome in children","author":"Durkan","year":"2005","journal-title":"Cochrane Database of Systematic Reviews"},{"issue":"1","key":"10.1002\/14651858.CD002290.pub6-BIB0244|cit244","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD002290.pub3","article-title":"Non-corticosteroid treatment for nephrotic syndrome in children","author":"Hodson","year":"2008","journal-title":"Cochrane Database of Systematic Reviews"},{"issue":"4","key":"10.1002\/14651858.CD002290.pub6-BIB0245|cit245","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD002290.pub5","article-title":"Non-corticosteroid immunosuppressive medications for steroid-sensitive nephrotic syndrome in children","author":"Larkins","year":"2020","journal-title":"Cochrane Database of Systematic Reviews"},{"issue":"10","key":"10.1002\/14651858.CD002290.pub6-BIB0246|cit246","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD002290.pub4","article-title":"Non-corticosteroid immunosuppressive medications for steroid-sensitive nephrotic syndrome in children","author":"Pravitsitthikul","year":"2013","journal-title":"Cochrane Database of Systematic Reviews"}],"container-title":["Cochrane Database of Systematic Reviews"],"original-title":[],"language":"en","deposited":{"date-parts":[[2025,12,29]],"date-time":"2025-12-29T00:09:30Z","timestamp":1766966970000},"score":1,"resource":{"primary":{"URL":"http:\/\/doi.wiley.com\/10.1002\/14651858.CD002290.pub6"}},"subtitle":[],"editor":[{"name":"Cochrane Kidney and Transplant Group","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2024,11,8]]},"references-count":246,"journal-issue":{"issue":"11","published-online":{"date-parts":[[2024,11]]}},"URL":"https:\/\/doi.org\/10.1002\/14651858.cd002290.pub6","relation":{},"ISSN":["1465-1858"],"issn-type":[{"value":"1465-1858","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,11,8]]}}}