{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T11:02:48Z","timestamp":1791025368312,"version":"4.1.0"},"publisher-location":"Chichester, UK","reference-count":114,"publisher":"John Wiley & Sons, Ltd","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"DOI":"10.1002\/14651858.cd003002.pub2","type":"reference-entry","created":{"date-parts":[[2006,5,9]],"date-time":"2006-05-09T20:10:34Z","timestamp":1147205434000},"source":"Crossref","is-referenced-by-count":59,"title":["Drug therapy for obstructive sleep apnoea in adults"],"prefix":"10.1002","author":[{"given":"Ian","family":"Smith","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toby J","family":"Lasserson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John J","family":"Wright","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2006,4,19]]},"reference":[{"issue":"4","key":"10.1002\/14651858.CD003002.pub2-BIB1|cit1","first-page":"233","article-title":"Naloxone improves sleep apnea in obese humans","volume":"9","author":"Atkinson","year":"1985","journal-title":"International Journal of Obesity"},{"issue":"17","key":"10.1002\/14651858.CD003002.pub2-BIB2|cit2","doi-asserted-by":"crossref","first-page":"1037","DOI":"10.1056\/NEJM198210213071701","article-title":"Protriptyline in obstructive sleep apnoea: a double blind trial","volume":"307","author":"Brownell","year":"1982","journal-title":"New England Journal of Medicine"},{"key":"10.1002\/14651858.CD003002.pub2-BIB3|cit3","unstructured":"Carley D Olopade C Seink S Radulovacki M Serotonin antagonist improves obstructive sleep apnoea Sleep Medicine 2003 Poster 024"},{"issue":"2","key":"10.1002\/14651858.CD003002.pub2-BIB4|cit4","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1378\/chest.96.2.262","article-title":"Indices of severity of obstructive sleep apnoea syndrome do not change during medroxyprogesterone acetate therapy","volume":"96","author":"Cook","year":"1989","journal-title":"Chest"},{"issue":"Suppl 4","key":"10.1002\/14651858.CD003002.pub2-BIB5|cit5","first-page":"235","article-title":"Effect of Naloxone in obstructive sleep apnoea","volume":"125","author":"Diamond","year":"1982","journal-title":"American Review of Respiratory Disease"},{"key":"10.1002\/14651858.CD003002.pub2-BIB6|cit6","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1164\/ajrccm\/136.1.80","article-title":"The effects of aminophylline on sleep and sleep-disordered breathing in patients with obstructive sleep apnoea","volume":"136","author":"Espinoza","year":"1987","journal-title":"American Review of Respiratory Diseases"},{"issue":"3","key":"10.1002\/14651858.CD003002.pub2-BIB7|cit7","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1111\/j.1365-2869.1993.tb00079.x","article-title":"Naltrexone improves blood gas patterns in obstructive sleep apnoea syndrome through its influence on sleep","volume":"2","author":"Ferber","year":"1993","journal-title":"Journal of Sleep Research"},{"issue":"Suppl 3","key":"10.1002\/14651858.CD003002.pub2-BIB8|cit8","first-page":"S78","article-title":"Twenty-four-hour blood pressure control: Effect of cilazapril on continuous arterial blood pressure during sleep, and physical and mental load in patients with arterial hypertension and sleep apnea","volume":"24","author":"Grote","year":"1994","journal-title":"Journal of Cardiovascular Pharmacology"},{"issue":"10","key":"10.1002\/14651858.CD003002.pub2-BIB9|cit9","first-page":"500","article-title":"Effect of cilazapril during the day and the night in patients with sleep apnea and arterial hypertension","volume":"21","author":"Grote","year":"1992","journal-title":"Nieren und Hochdruckkrankheiten"},{"issue":"4","key":"10.1002\/14651858.CD003002.pub2-BIB10|cit10","doi-asserted-by":"crossref","first-page":"235","DOI":"10.3109\/08037059709062075","article-title":"Effect of angiotensin converting enzyme inhibition [Cilazapril] on blood pressure recording in hypertensive obstructive sleep apneic patients","volume":"6","author":"Grote","year":"1997","journal-title":"Blood Pressure"},{"issue":"3","key":"10.1002\/14651858.CD003002.pub2-BIB11|cit11","first-page":"183","article-title":"Effect of cilazapril on blood pressure and heart rate in sleep apnea patients","volume":"24","author":"Grote","year":"1995","journal-title":"Nieren und Hochdruckkrankheiten"},{"issue":"1","key":"10.1002\/14651858.CD003002.pub2-BIB12|cit12","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1111\/j.1365-2869.1995.tb00199.x","article-title":"Arterial hypertension and sleep apnoea: effect of the angiotensin-converting enzyme (ACE) inhibitor cilazapril on continuously measured blood pressure during sleep and wakefulness","volume":"4","author":"Grote","year":"1995","journal-title":"Journal of Sleep Research"},{"issue":"12","key":"10.1002\/14651858.CD003002.pub2-BIB13|cit13","doi-asserted-by":"crossref","first-page":"1280","DOI":"10.1016\/S0895-7061(00)01207-3","article-title":"Association between blood pressure reduction with antihypertensive treatment and sleep apnea activity","volume":"13","author":"Grote","year":"2000","journal-title":"American Journal of Hypertension"},{"key":"10.1002\/14651858.CD003002.pub2-BIB14|cit14","first-page":"170","article-title":"Nocturnal hypertension and sleep apnea: effect of the ACE inhibitor cilazapril on apnea-induced blood pressure increases during sleep","volume":"49","author":"Grote","year":"1995","journal-title":"Pneumologie"},{"issue":"4","key":"10.1002\/14651858.CD003002.pub2-BIB15|cit15","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1093\/sleep\/19.4.287","article-title":"A double blind, randomized trial of sabeluzole - a putative glutamate antagonist - in obstructive sleep apnoea","volume":"19","author":"Hedner","year":"1996","journal-title":"Sleep"},{"issue":"10","key":"10.1002\/14651858.CD003002.pub2-BIB16|cit16","doi-asserted-by":"crossref","first-page":"1246","DOI":"10.1164\/rccm.200211-1344OC","article-title":"Reduction of sleep-disordered breathing after physostigmine","volume":"168","author":"Hedner","year":"2003","journal-title":"American Journal of Respiratory & Critical Care Medicine"},{"key":"10.1002\/14651858.CD003002.pub2-BIB17|cit17","first-page":"391","article-title":"The therapeutic effect of theophylline in mild obstructive sleep apnea\/hypopnea syndrome: results of repeated measurements with portable recording devices at home","volume":"5","author":"Hein","year":"2000","journal-title":"European Journal of Medical Research"},{"issue":"9-10","key":"10.1002\/14651858.CD003002.pub2-BIB18|cit18","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1007\/s002280050536","article-title":"Cardiovascular effects of mibefradil in hypertensive patients with obstructive sleep apnea","volume":"54","author":"Heitmann","year":"1998","journal-title":"European Journal of Clinical Pharmacology"},{"issue":"2","key":"10.1002\/14651858.CD003002.pub2-BIB19|cit19","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1164\/ajrccm\/145.2_Pt_1.435","article-title":"Effect of clonidine in obstructive sleep apnea","volume":"145","author":"Issa","year":"1992","journal-title":"American Review of Respiratory Diseases"},{"issue":"5","key":"10.1002\/14651858.CD003002.pub2-BIB20|cit20","doi-asserted-by":"crossref","first-page":"1522","DOI":"10.1164\/ajrccm.157.5.9708070","article-title":"Surface tension forces in sleep apnea: the role of a soft tissue lubricant: a randomized double-blind, placebo-controlled trial","volume":"157","author":"Jokic","year":"1998","journal-title":"American Journal of Respiratory and Critical Care Medicine"},{"issue":"Suppl 3","key":"10.1002\/14651858.CD003002.pub2-BIB21|cit21","first-page":"A283","article-title":"Effects of intranasal fluticasone propionate on snoring and sleep apnea","volume":"157","author":"Kiely","year":"1998","journal-title":"American Journal of Respiratory and Critical Care Medicine"},{"issue":"1","key":"10.1002\/14651858.CD003002.pub2-BIB22|cit22","first-page":"50","article-title":"Intranasal corticosteroid therapy for obstructive sleep apnoea in patients with co-existing rhinitis","volume":"59","author":"Kiely","year":"2004","journal-title":"Thorax"},{"issue":"1","key":"10.1002\/14651858.CD003002.pub2-BIB23|cit23","first-page":"61","article-title":"Effect of serotonin uptake inhibition on breathing during sleep and daytime symptoms in obstructive sleep apnea","volume":"22","author":"Kraiczi","year":"1999","journal-title":"Sleep"},{"issue":"5","key":"10.1002\/14651858.CD003002.pub2-BIB24|cit24","first-page":"697","article-title":"Effects of a ventilatory stimulant, almitrine bismesylate, in the sleep apnea syndrome","volume":"32","author":"Krieger","year":"1982","journal-title":"Current Therapeutic Research, Clinical & Experimental"},{"issue":"6","key":"10.1002\/14651858.CD003002.pub2-BIB25|cit25","first-page":"899","article-title":"Effect of oral almitrine on the sleep apnea syndrome","volume":"11","author":"Mangin","year":"1983","journal-title":"Revue Fran\u00e7aise des Maladies Respiratoires"},{"issue":"1","key":"10.1002\/14651858.CD003002.pub2-BIB26|cit26","first-page":"71","article-title":"Buspirone administration to sleep apnea patients","volume":"11","author":"Mendelson","year":"1991","journal-title":"Journal of Clinical Pharmacology"},{"issue":"3","key":"10.1002\/14651858.CD003002.pub2-BIB27|cit27","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1378\/chest.101.3.753","article-title":"Theophylline in obstructive sleep apnoea","volume":"101","author":"Mulloy","year":"1992","journal-title":"Chest"},{"issue":"4","key":"10.1002\/14651858.CD003002.pub2-BIB28|cit28","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1007\/s11325-999-0125-1","article-title":"Obstructive sleep apnea and hypopnea efficacy and safety of a long-acting beta2-agonist","volume":"3","author":"Rasche","year":"1999","journal-title":"Sleep Breath"},{"issue":"1","key":"10.1002\/14651858.CD003002.pub2-BIB29|cit29","first-page":"11","article-title":"Effect of salmeterol in obstructive sleep apnea syndrome","volume":"52","author":"Rasche","year":"1998","journal-title":"Pneumologie"},{"issue":"1","key":"10.1002\/14651858.CD003002.pub2-BIB30|cit30","first-page":"5","article-title":"A double-blind trial of protriptyline in the treatment of sleep apnoea syndrome","volume":"36","author":"Stepanski","year":"1988","journal-title":"Henry Ford Hospital Medical Journal"},{"key":"10.1002\/14651858.CD003002.pub2-BIB31|cit31","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1046\/j.1365-2869.2003.00342.x","article-title":"Effect of ondansetron on moderate obstructive sleep apnoea, a single night placebo-controlled trial","volume":"12","author":"Stradling","year":"2003","journal-title":"Journal of Sleep Research"},{"key":"10.1002\/14651858.CD003002.pub2-BIB32|cit32","series-title":"American Thoracic Society International Conference; May 17-22; Atlanta, Georgia","article-title":"Effect of ondansetron on moderate obstructive sleep apnea (OSA), single night, randomised, placebo-controlled trial","author":"Stradling","year":"2002"},{"issue":"2","key":"10.1002\/14651858.CD003002.pub2-BIB33|cit33","first-page":"127","article-title":"Effect of doxapram on obstructive sleep apnea","volume":"22","author":"Suratt","year":"1986","journal-title":"Bulletin Europeen de Physiopathologie Respiratoire"},{"issue":"5","key":"10.1002\/14651858.CD003002.pub2-BIB34|cit34","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1093\/sleep\/11.5.463","article-title":"Role of protriptyline and acetazolomide in the sleep apnea\/hypopnea syndrome","volume":"11","author":"Whyte","year":"1988","journal-title":"Sleep"},{"key":"10.1002\/14651858.CD003002.pub2-BIB35|cit35","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1159\/000115991","article-title":"Preliminary clinical experience with imipramine HCl in the treatment of sleep apnea syndrome","volume":"25","author":"Ami-Hai","year":"1986","journal-title":"European Neurology"},{"key":"10.1002\/14651858.CD003002.pub2-BIB36|cit36","first-page":"776","article-title":"Medroxyprogesterone acetate in the treatment of obstructive sleep apnoea","volume":"31","author":"Anonymous","year":"1997","journal-title":"The Annals of Pharmacotherapy"},{"issue":"6","key":"10.1002\/14651858.CD003002.pub2-BIB37|cit37","doi-asserted-by":"crossref","first-page":"640","DOI":"10.1016\/S0895-7061(96)00507-9","article-title":"Short-term antihypertensive medication does not exacerbate sleep- disordered breathing in newly diagnosed hypertensive patients","volume":"10","author":"Bartel","year":"1997","journal-title":"American Journal of Hypertension"},{"key":"10.1002\/14651858.CD003002.pub2-BIB38|cit38","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1016\/0002-9343(81)90572-6","article-title":"Menopause, medroxyprogesterone and breathing during sleep","volume":"70","author":"Block","year":"1981","journal-title":"The American Journal of Medicine"},{"issue":"1","key":"10.1002\/14651858.CD003002.pub2-BIB39|cit39","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1046\/j.1439-054X.2003.02190.x","article-title":"The therapeutic effect of theophylline on sustained attention in patients with obstructive sleep apnea","volume":"7","author":"Buttner","year":"2003","journal-title":"Somnologie"},{"issue":"8","key":"10.1002\/14651858.CD003002.pub2-BIB40|cit40","doi-asserted-by":"crossref","first-page":"644","DOI":"10.1093\/sleep\/18.8.644","article-title":"The effect of Temazepam on respiration in elderly insomniacs with mild sleep apnea","volume":"18","author":"Camacho","year":"1995","journal-title":"Sleep"},{"key":"10.1002\/14651858.CD003002.pub2-BIB41|cit41","first-page":"25","article-title":"Tricyclic antidrepressants in the treatment of insomnia","volume":"2","author":"Catesby-Ware","year":"1983","journal-title":"Journal of Clinical Psychiatry"},{"key":"10.1002\/14651858.CD003002.pub2-BIB42|cit42","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1136\/thx.49.7.699","article-title":"Effect of short term hormone replacement in the treatment of obstructive sleep apnoea in postmenopausal women","volume":"49","author":"Cistulli","year":"1994","journal-title":"Thorax"},{"issue":"9 (Pt i)","key":"10.1002\/14651858.CD003002.pub2-BIB43|cit43","doi-asserted-by":"crossref","first-page":"1287","DOI":"10.1212\/WNL.29.9_Part_1.1287","article-title":"Sleep apnea: treatment with protriptyline","volume":"29","author":"Clark","year":"1979","journal-title":"Neurology"},{"issue":"3","key":"10.1002\/14651858.CD003002.pub2-BIB44|cit44","doi-asserted-by":"crossref","first-page":"792","DOI":"10.1378\/chest.106.3.792","article-title":"Medroxyprogesterone acetate and ethanol-induced exacerbation of obstructive sleep apnoea","volume":"106","author":"Collop","year":"1994","journal-title":"Chest"},{"key":"10.1002\/14651858.CD003002.pub2-BIB45|cit45","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1136\/thx.37.1.49","article-title":"Protriptyline in the treatment of sleep apnoea","volume":"37","author":"Conway","year":"1982","journal-title":"Thorax"},{"issue":"2","key":"10.1002\/14651858.CD003002.pub2-BIB46|cit46","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1164\/ajrccm.150.2.8049831","article-title":"Acute effects of transdermal nicotine on sleep architecture, snoring, and sleep-disordered breathing in nonsmokers","volume":"150","author":"Davila","year":"1994","journal-title":"American Journal of Respiratory Critical Care Medicine"},{"key":"10.1002\/14651858.CD003002.pub2-BIB47|cit47","first-page":"120","article-title":"Drug treatment of sleep apnoea: results of a short term course of theophylline","volume":"78","author":"Martino","year":"1999","journal-title":"Rhinologie"},{"issue":"5","key":"10.1002\/14651858.CD003002.pub2-BIB48|cit48","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1016\/S1389-9457(03)00108-4","article-title":"Effects of modafinil on sustained attention performance and quality of life in OSA patients with residual sleepiness while being treated with nCPAP","volume":"4","author":"Dinges","year":"2003","journal-title":"Sleep Medicine"},{"issue":"Suppl","key":"10.1002\/14651858.CD003002.pub2-BIB49|cit49","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1111\/j.1472-8206.1997.tb00891.x","article-title":"Hypertension and sleep apnoea syndrome: detection of a circulating immunoreactive substance with anti-clonidine antibodies","volume":"11","author":"Dontenwill","year":"1997","journal-title":"Fundamental & Clinical Pharmacology"},{"key":"10.1002\/14651858.CD003002.pub2-BIB50|cit50","first-page":"287","article-title":"Treatment of sleep apnoea with theophylline","volume":"45","author":"Dorow","year":"1991","journal-title":"Pneumologie"},{"key":"10.1002\/14651858.CD003002.pub2-BIB51|cit51","doi-asserted-by":"crossref","first-page":"141","DOI":"10.3109\/07853899708998790","article-title":"Effects of sex steroids on sleep","volume":"31","author":"Empson","year":"1999","journal-title":"Annals of Medicine"},{"issue":"5","key":"10.1002\/14651858.CD003002.pub2-BIB52|cit52","first-page":"370","article-title":"Non-surgical alternatives to continuous positive airway pressure","volume":"43","author":"Epstein","year":"1998","journal-title":"Respiratory Care"},{"key":"10.1002\/14651858.CD003002.pub2-BIB53|cit53","first-page":"716","article-title":"Results of pharmacological, mechanical and surgical treatments in obstructive sleep apnoea","volume":"47","author":"Fietz","year":"1993","journal-title":"Pnuemologie"},{"issue":"2","key":"10.1002\/14651858.CD003002.pub2-BIB54|cit54","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1183\/09031936.95.08020230","article-title":"The effects of the GABA agonist, baclofen, on sleep and breathing","volume":"8","author":"Finnimore","year":"1995","journal-title":"European Respiratory Journal"},{"issue":"6","key":"10.1002\/14651858.CD003002.pub2-BIB55|cit55","doi-asserted-by":"crossref","first-page":"1282","DOI":"10.1164\/ajrccm\/143.6.1282","article-title":"Endogenous opiates modulate the postapnea ventilatory response in the obstructive sleep apnea syndrome","volume":"143","author":"Greenberg","year":"1991","journal-title":"American Review of Respiratory Disease"},{"key":"10.1002\/14651858.CD003002.pub2-BIB56|cit56","first-page":"632","article-title":"Naloxone, theophylline, bromocriptine and obstructive sleep apnoea. Negative results","volume":"19","author":"Guilleminault","year":"1983","journal-title":"Bulletin Europeen de Physiopathologie Respiratoire"},{"key":"10.1002\/14651858.CD003002.pub2-BIB57|cit57","doi-asserted-by":"crossref","first-page":"896","DOI":"10.1164\/arrd.1987.135.4.896","article-title":"Respiratory stimulants and sleep periodic breathing at high altitude","volume":"135","author":"Hackett","year":"1987","journal-title":"American review of Respiratory Diseases"},{"issue":"2","key":"10.1002\/14651858.CD003002.pub2-BIB58|cit58","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1378\/chest.100.2.416","article-title":"Response of obstructive sleep apnea to fluoxetine and protriptyline","volume":"100","author":"Hanzel","year":"1991","journal-title":"Chest"},{"issue":"Suppl 1","key":"10.1002\/14651858.CD003002.pub2-BIB59|cit59","first-page":"185","article-title":"Nicotine for therapy of obstructive sleep apnea?","volume":"49","author":"Hein","year":"1995","journal-title":"Pneumologie"},{"issue":"11","key":"10.1002\/14651858.CD003002.pub2-BIB60|cit60","doi-asserted-by":"crossref","first-page":"2011","DOI":"10.1183\/09031936.94.07112011","article-title":"Nitrazepam in patients with sleep apnoea: a double-blind placebo-controlled study","volume":"7","author":"Hoijer","year":"1994","journal-title":"European Respiratory Journal"},{"key":"10.1002\/14651858.CD003002.pub2-BIB61|cit61","doi-asserted-by":"crossref","first-page":"1346","DOI":"10.1378\/chest.109.5.1346","article-title":"Treatment of obstructive sleep apnoea","volume":"109","author":"Hudgel","year":"1996","journal-title":"Chest"},{"key":"10.1002\/14651858.CD003002.pub2-BIB62|cit62","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1164\/ajrccm.158.3.9802019","article-title":"Pharmacologic treatment of sleep-disordered breathing","volume":"158","author":"Hudgel","year":"1998","journal-title":"American Journal of Respiratory Critical Care Medicine"},{"issue":"Suppl 4a","key":"10.1002\/14651858.CD003002.pub2-BIB63|cit63","doi-asserted-by":"crossref","first-page":"120s","DOI":"10.1016\/S0002-9343(99)00350-2","article-title":"Obstructive sleep apnea and gastroesophageal reflux","volume":"108","author":"Ing","year":"2000","journal-title":"American Journal of Medicine"},{"key":"10.1002\/14651858.CD003002.pub2-BIB64|cit64","first-page":"276","article-title":"Pharmacological therapy for sleep disordered breathing","volume":"45","author":"Kauffmann","year":"1991","journal-title":"Pneumologie"},{"key":"10.1002\/14651858.CD003002.pub2-BIB65|cit65","first-page":"279","article-title":"Comparsion of nCPAP, theophylline and O2 therapy in patients with sleep apnoea","volume":"45","author":"Kempf","year":"1991","journal-title":"Pneumologie"},{"issue":"4","key":"10.1002\/14651858.CD003002.pub2-BIB66|cit66","doi-asserted-by":"crossref","first-page":"918","DOI":"10.1164\/ajrccm.163.4.2005036","article-title":"Randomized, double-blind, placebo-controlled crossover trial of modafinil in the treatment of residual excessive daytime sleppiness in the sleep apnea\/hypopnea syndrome","volume":"163","author":"Kingshott","year":"2001","journal-title":"American Journal of Critical Care Medicine"},{"key":"10.1002\/14651858.CD003002.pub2-BIB67|cit67","first-page":"825","article-title":"Short-term use of fluoxetine in asymptomatic obese subjects with sleep-related hypoventilation","volume":"16","author":"Kopelman","year":"1992","journal-title":"International Journal of Obesity & Related Metabolic Disorders"},{"issue":"5","key":"10.1002\/14651858.CD003002.pub2-BIB68|cit68","first-page":"515","article-title":"New frontiers in the management of obstructive sleep apnoea syndrome","volume":"53","author":"Krieger","year":"1998","journal-title":"Monaldi Archives for Chest Disease"},{"key":"10.1002\/14651858.CD003002.pub2-BIB69|cit69","doi-asserted-by":"crossref","first-page":"1417","DOI":"10.1097\/00007611-198311000-00023","article-title":"Saturday conference: sleep apnoea syndrome","volume":"76","author":"Lloyd","year":"1983","journal-title":"Southern Medical Journal"},{"issue":"6","key":"10.1002\/14651858.CD003002.pub2-BIB70|cit70","doi-asserted-by":"crossref","first-page":"1317","DOI":"10.1016\/S0025-7125(16)30989-0","article-title":"Medical therapy of obstructive sleep apnoea","volume":"69","author":"Lombard","year":"1985","journal-title":"Medical clinics of North America"},{"issue":"5","key":"10.1002\/14651858.CD003002.pub2-BIB71|cit71","doi-asserted-by":"crossref","first-page":"1426","DOI":"10.1378\/chest.116.5.1426","article-title":"Technologic advances in the treatment of obstructive sleep apnoea syndrome","volume":"116","author":"Loube","year":"1999","journal-title":"Chest"},{"issue":"Suppl 9","key":"10.1002\/14651858.CD003002.pub2-BIB72|cit72","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1093\/sleep\/19.suppl_9.S101","article-title":"Management of simple snoring, upper airway resistance syndrome and moderate sleep apnoea syndrome","volume":"19","author":"L\u00e9vy","year":"1996","journal-title":"Sleep"},{"issue":"5","key":"10.1002\/14651858.CD003002.pub2-BIB73|cit73","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1016\/j.sleep.2005.02.003","article-title":"Sibutramine does not worsen sleep apnea syndrome: A randomized double-blind placebo-controlled study","volume":"6","author":"Martinez","year":"2005","journal-title":"Sleep Medicine"},{"issue":"6","key":"10.1002\/14651858.CD003002.pub2-BIB74|cit74","doi-asserted-by":"crossref","first-page":"952","DOI":"10.1097\/00005344-199012000-00014","article-title":"Influence of metoprolol and cilazapril on blood pressure and on sleep apnea activity","volume":"16","author":"Mayer","year":"1990","journal-title":"Journal of Cardiovascular Pharmacology"},{"issue":"Suppl 1","key":"10.1002\/14651858.CD003002.pub2-BIB75|cit75","doi-asserted-by":"crossref","first-page":"37","DOI":"10.2165\/00003495-199100411-00008","article-title":"First experience with cilazapril in the treatment of sleep apnoea-related hypertension","volume":"41","author":"Mayer","year":"1991","journal-title":"Drugs"},{"key":"10.1002\/14651858.CD003002.pub2-BIB76|cit76","first-page":"144","article-title":"Overview of management options for snoring and sleep apnoea","volume":"10","author":"Montserrat","year":"1998","journal-title":"European Respiratory Monograph"},{"issue":"9","key":"10.1002\/14651858.CD003002.pub2-BIB77|cit77","doi-asserted-by":"crossref","first-page":"1675","DOI":"10.1164\/ajrccm.164.9.2103032","article-title":"Modafinil as adjunct therapy for daytime sleepiness in obstructive sleep apnea","volume":"164","author":"Pack","year":"2001","journal-title":"American Journal of Respiratory and Critical Care Medicine"},{"issue":"6","key":"10.1002\/14651858.CD003002.pub2-BIB78|cit78","doi-asserted-by":"crossref","first-page":"2192","DOI":"10.1378\/chest.124.6.2192","article-title":"Modafinil as adjunct therapy for daytime sleepiness in obstructive sleep apnea: a 12-week, open-label study","volume":"124","author":"Schwartz","year":"2003","journal-title":"Chest"},{"issue":"2","key":"10.1002\/14651858.CD003002.pub2-BIB79|cit79","first-page":"88","article-title":"Effects of antihypertensive medication on hypertension in patients with sleep apnoea","volume":"3","author":"Pelttari","year":"1994","journal-title":"Blood Pressure"},{"issue":"3","key":"10.1002\/14651858.CD003002.pub2-BIB80|cit80","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1016\/S0895-7061(97)00469-X","article-title":"Little effect of ordinary antihypertensive therapy on nocturnal high blood pressure in patients with sleep disordered breathing","volume":"11","author":"Pelttari","year":"1998","journal-title":"American Journal of Hypertension"},{"key":"10.1002\/14651858.CD003002.pub2-BIB81|cit81","first-page":"433","article-title":"Treatment of sleep apnoea with sustained release theophylline administered at night","volume":"41","author":"Peter","year":"1987","journal-title":"Praxis und Klinik der Pneumologie"},{"issue":"4","key":"10.1002\/14651858.CD003002.pub2-BIB82|cit82","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1093\/sleep\/22.4.507","article-title":"Effect of celiprolol treatment in hypertensive patients with sleep apnea","volume":"22","author":"Planes","year":"1999","journal-title":"Sleep"},{"key":"10.1002\/14651858.CD003002.pub2-BIB83|cit83","first-page":"625","article-title":"L-tryptophan in the treatment of impaired respiration in sleep","volume":"19","author":"Schmidt","year":"1983","journal-title":"Bulletin Europeen de Physiopathologie Respiratoire"},{"key":"10.1002\/14651858.CD003002.pub2-BIB84|cit84","doi-asserted-by":"crossref","first-page":"1389","DOI":"10.1164\/ajrccm\/146.6.1389","article-title":"Androgem blockade does not affect sleep-disordered breathing ir chemosensitivity in men with obstructive sleep apnea","volume":"146","author":"Stewart","year":"1992","journal-title":"American Review of Respiratory Diseases"},{"key":"10.1002\/14651858.CD003002.pub2-BIB85|cit85","first-page":"791","article-title":"Physiologic basis of therapy for sleep apnoea","volume":"134","author":"Strohl","year":"1986","journal-title":"American review of respiratory diseases"},{"key":"10.1002\/14651858.CD003002.pub2-BIB86|cit86","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1111\/j.1651-2227.1995.tb13758.x","article-title":"CPAP treatment of obstructive sleep apnoea and neurodevelopmental deficits","volume":"84","author":"Tirosh","year":"1995","journal-title":"Acta Paediatrica"},{"key":"10.1002\/14651858.CD003002.pub2-BIB87|cit87","first-page":"549","article-title":"Arterial oxygenation and breathing during sleep in normal pregnancy","volume":"27","author":"Trakada","year":"1999","journal-title":"Medical Science Research"},{"issue":"9","key":"10.1002\/14651858.CD003002.pub2-BIB88|cit88","doi-asserted-by":"crossref","first-page":"4409","DOI":"10.1210\/jc.2003-031929","article-title":"Marked decrease in sleepiness in patients with sleep apnea by Etanercept, a tumor necrosis factor-alpha antagonist","volume":"89","author":"Vgontzas","year":"2004","journal-title":"The Journal of Clinical Endocrinology and Metabolism"},{"key":"10.1002\/14651858.CD003002.pub2-BIB89|cit89","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1159\/000174776","article-title":"Influence of antihypertensive drug therapy on sleep pattern and sleep apnoea activity","volume":"78","author":"Weichler","year":"1991","journal-title":"Cardiology"},{"issue":"Suppl 1","key":"10.1002\/14651858.CD003002.pub2-BIB90|cit90","first-page":"13","article-title":"Organic psychosyndrom and sleep apnoea. Transdermal nicotin a new concept of therapie?","volume":"49","author":"Wirth","year":"1995","journal-title":"Pneumologie"},{"issue":"3","key":"10.1002\/14651858.CD003002.pub2-BIB91|cit91","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1097\/00045391-200305000-00004","article-title":"Clinical effects of locally delivered nicotine in obstructive sleep apnea syndrome","volume":"10","author":"Zevin","year":"2003","journal-title":"American Journal of Therapeutics"},{"issue":"Suppl 2","key":"10.1002\/14651858.CD003002.pub2-BIB92|cit92","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1136\/thx.53.2008.S58","article-title":"Oral appliances for the management of snoring and obstructive sleep apnoea","volume":"53","author":"Bennett","year":"1998","journal-title":"Thorax"},{"key":"10.1002\/14651858.CD003002.pub2-BIB93|cit93","first-page":"144","article-title":"Time course of change in ventilatory response to CO2 with long-term CPAP therapy for obstructive sleep apnea","volume":"135","author":"Berthon-Jones","year":"1987","journal-title":"American Review of Respiratory Disease"},{"key":"10.1002\/14651858.CD003002.pub2-BIB94|cit94","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1159\/000029354","article-title":"Nasopharyngeal symptoms in patient with obstructive sleep apnea syndrome","volume":"66","author":"Brander","year":"1999","journal-title":"Respiration"},{"issue":"5","key":"10.1002\/14651858.CD003002.pub2-BIB95|cit95","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1016\/j.sleep.2004.06.004","article-title":"Effectiveness of mirtazapine in the treatment of sleep apnea\/hypopnea syndrome (SAHS)","volume":"5","author":"Castillo","year":"2004","journal-title":"Sleep Medicine"},{"key":"10.1002\/14651858.CD003002.pub2-BIB96|cit96","doi-asserted-by":"crossref","first-page":"1477","DOI":"10.1378\/chest.109.6.1477","article-title":"A crossover study comparing the efficacy of continuous positive airway pressure with anterior mandibular positioning devices on patients with obstructive sleep apnea","volume":"1009","author":"Clark","year":"1996","journal-title":"Chest"},{"key":"10.1002\/14651858.CD003002.pub2-BIB97|cit97","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1136\/thx.53.5.341","article-title":"Randomised placebo controlled trial of daytime function after continuous positive airway pressure (CPAP) therapy for the sleep apnoea\/hypopnoea syndrome","volume":"53","author":"Engleman","year":"1998","journal-title":"Thorax"},{"issue":"1","key":"10.1002\/14651858.CD003002.pub2-BIB98|cit98","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1212\/01.WNL.0000073624.13436.32","article-title":"Obstructive sleep apnea is related to a thalamic cholinergic deficit in MSA","volume":"61","author":"Gilman","year":"2003","journal-title":"Neurology"},{"key":"10.1002\/14651858.CD003002.pub2-BIB99|cit99","article-title":"Analysing and presenting results","volume-title":"Cochrane Reviewers\u2019 Handbook 4.2.2 [updated December 2003]; Section 8, The Cochrane Library","author":"Deeks","year":"2004"},{"issue":"4","key":"10.1002\/14651858.CD003002.pub2-BIB100|cit100","article-title":"Interventions to improve compliance with continuous positive airway pressure for obstructive sleep apnoea (Cochrane review)","author":"Haniffa","year":"2004","journal-title":"The Cochrane Database of Systematic Reviews"},{"key":"10.1002\/14651858.CD003002.pub2-BIB101|cit101","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1378\/chest.94.1.9","article-title":"Mortality and apnea index in obstructive sleep apnea","volume":"94","author":"He","year":"1988","journal-title":"Chest"},{"key":"10.1002\/14651858.CD003002.pub2-BIB102|cit102","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1136\/bmj.327.7414.557","article-title":"Measuring inconsistency in meta-analyses","volume":"327","author":"Higgins","year":"2003","journal-title":"BMJ"},{"issue":"1","key":"10.1002\/14651858.CD003002.pub2-BIB103|cit103","first-page":"13","article-title":"Pharmacologic treatment of obstructive sleep apnea","volume":"126","author":"Hudgel","year":"1995","journal-title":"Journal of Laboratory & Clinical Medicine"},{"issue":"1","key":"10.1002\/14651858.CD003002.pub2-BIB104|cit104","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0197-2456(95)00134-4","article-title":"Assessing the quality of reports of randomized clinical trials: is blinding necessary?","volume":"17","author":"Jadad","year":"1996","journal-title":"Controlled Clinical Trials"},{"issue":"9170","key":"10.1002\/14651858.CD003002.pub2-BIB105|cit105","doi-asserted-by":"crossref","first-page":"2100","DOI":"10.1016\/S0140-6736(98)10532-9","article-title":"Comparison of therapeutic and subtherapeutic nasal continuous positive airway pressure for obstructive sleep apnoea: a randomised prospective parallel trial","volume":"353","author":"Jenkinson","year":"1999","journal-title":"Lancet"},{"issue":"4","key":"10.1002\/14651858.CD003002.pub2-BIB106|cit106","doi-asserted-by":"crossref","DOI":"10.1002\/14651858.CD003136","article-title":"Adenotonsillectomy for obstructive sleep apnoea in children (Cochrane review)","author":"Lim","year":"2001","journal-title":"The Cochrane Database of Systematic Reviews"},{"issue":"4","key":"10.1002\/14651858.CD003002.pub2-BIB107|cit107","doi-asserted-by":"crossref","DOI":"10.1002\/14651858.CD004435.pub2","article-title":"Oral appliances for obstructive sleep apnoea (Cochrane review)","author":"Lim","year":"2004","journal-title":"The Cochrane Database of Systematic Reviews"},{"issue":"10","key":"10.1002\/14651858.CD003002.pub2-BIB108|cit108","doi-asserted-by":"crossref","first-page":"1910","DOI":"10.1164\/ajrccm.164.10.2101072","article-title":"Sleep-disordered breathing and coronary artery disease: long-term prognosis","volume":"164","author":"Mooe","year":"2001","journal-title":"American Journal of Respiratory & Critcal Care Medicine"},{"key":"10.1002\/14651858.CD003002.pub2-BIB109|cit109","doi-asserted-by":"crossref","first-page":"1124","DOI":"10.1164\/ajrccm.160.4.9802027","article-title":"Effective compliance during the first 3 months of continuous positive airway pressure treatment. A European prospective study of 121 patients","volume":"160","author":"Pepin","year":"1999","journal-title":"American Journal of Respiratory & Critical Care Medicine"},{"issue":"4","key":"10.1002\/14651858.CD003002.pub2-BIB110|cit110","doi-asserted-by":"crossref","DOI":"10.1002\/14651858.CD002875","article-title":"Lifestyle modification for obstructive sleep apnoea (Cochrane review)","author":"Snheerson","year":"2001","journal-title":"The Cochrane Database of Systematic Reviews"},{"key":"10.1002\/14651858.CD003002.pub2-BIB111|cit111","unstructured":"Scottish Intercollegiate Guideline Network Management of obstructive sleep apnoea\/hypopnoea syndrome in adults (guideline no. 73) www.sign.ac.uk"},{"issue":"1","key":"10.1002\/14651858.CD003002.pub2-BIB112|cit112","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1164\/ajrccm.159.1.9805074","article-title":"Variation in the arousal pattern after obstructive events in obstructive sleep anpea","volume":"159","author":"Stradling","year":"1999","journal-title":"American Journal of Respiratory and Critical Care Medicine"},{"issue":"8225","key":"10.1002\/14651858.CD003002.pub2-BIB113|cit113","doi-asserted-by":"crossref","first-page":"862","DOI":"10.1016\/S0140-6736(81)92140-1","article-title":"Reversal of obstructive sleep apnoea by continuous positive airway pressure applied through the nares","volume":"1","author":"Sullivan","year":"1981","journal-title":"Lancet"},{"issue":"4","key":"10.1002\/14651858.CD003002.pub2-BIB114|cit114","article-title":"Continuous positive airways pressure for obstructive sleep apnoea (Cochrane review)","author":"Wright","year":"2001","journal-title":"The Cochrane Database of Systematic Reviews"}],"updated-by":[{"DOI":"10.1002\/14651858.cd003002.pub3","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2013,5,31]],"date-time":"2013-05-31T00:00:00Z","timestamp":1369958400000}}],"container-title":["Cochrane Database of Systematic Reviews"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full\/10.1002\/14651858.CD003002.pub2","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,7]],"date-time":"2023-05-07T11:11:51Z","timestamp":1683457911000},"score":1,"resource":{"primary":{"URL":"https:\/\/doi.wiley.com\/10.1002\/14651858.CD003002.pub2"}},"subtitle":[],"editor":[{"given":"Ian","family":"Smith","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2006,4,19]]},"references-count":114,"URL":"https:\/\/doi.org\/10.1002\/14651858.cd003002.pub2","relation":{"new_version":[{"id-type":"doi","id":"10.1002\/14651858.CD003002.pub3","asserted-by":"object"}]},"subject":[],"published":{"date-parts":[[2006,4,19]]}}}