{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T18:32:54Z","timestamp":1792693974602,"version":"4.5.0"},"publisher-location":"Chichester, UK","reference-count":31,"publisher":"John Wiley & Sons, Ltd","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"DOI":"10.1002\/14651858.cd003427","type":"reference-entry","created":{"date-parts":[[2003,11,21]],"date-time":"2003-11-21T22:14:00Z","timestamp":1069452840000},"source":"Crossref","is-referenced-by-count":12,"title":["Prophylactic antibiotics for preventing pneumococcal infection in children with sickle cell disease"],"prefix":"10.1002","author":[{"given":"Ceri","family":"Hirst","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shirley","family":"Owusu-Ofori","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2002,7,22]]},"reference":[{"issue":"6430","key":"10.1002\/14651858.CD003427-BIB1|cit1","doi-asserted-by":"crossref","first-page":"1567","DOI":"10.1136\/bmj.288.6430.1567","article-title":"Prevention of pneumococcal infection in children with homozygous sickle cell disease","volume":"288","author":"John","year":"1984","journal-title":"British Medical Journal (Clinical Research Edition)"},{"issue":"1-2","key":"10.1002\/14651858.CD003427-BIB2|cit2","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1002\/sim.4780090111","article-title":"Sickle cell anaemia trial","volume":"9","author":"Gaston","year":"1990","journal-title":"Statistics in Medicine"},{"issue":"25","key":"10.1002\/14651858.CD003427-BIB3|cit3","doi-asserted-by":"crossref","first-page":"1593","DOI":"10.1056\/NEJM198606193142501","article-title":"Prophylaxis with oral penicillin in children with sickle cell anemia: a randomized trial","volume":"314","author":"Gaston","year":"1986","journal-title":"New England Journal of Medicine"},{"issue":"6","key":"10.1002\/14651858.CD003427-BIB4|cit4","doi-asserted-by":"crossref","first-page":"828","DOI":"10.1016\/S0022-3476(96)70026-4","article-title":"Serotype-specific immunoglobulin G antibody responses to pneumococcal vaccine in children with sickle cell anemia: effects of continued penicillin prophylaxis","volume":"129","author":"Bjornson","year":"1996","journal-title":"Journal of Pediatrics"},{"issue":"5","key":"10.1002\/14651858.CD003427-BIB5|cit5","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1016\/S0022-3476(95)70154-0","article-title":"Discontinuing penicillin prophylaxis in children with sickle cell anemia. Prophylactic Penicillin Study II","volume":"127","author":"Falletta","year":"1995","journal-title":"Journal of Pediatrics"},{"issue":"4","key":"10.1002\/14651858.CD003427-BIB6|cit6","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1097\/00043426-199707000-00011","article-title":"Influence of penicillin prophylaxis on antimicrobial resistance in nasopharyngeal S. pneumoniae among children with sickle cell anemia. The Ancillary Nasopharyngeal Culture Study of Prophylactic Penicillin Study II","volume":"19","author":"Woods","year":"1997","journal-title":"Journal of Pediatric Hematology\/Oncology"},{"issue":"6","key":"10.1002\/14651858.CD003427-BIB7|cit7","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1046\/j.1365-2125.1998.00730.x","article-title":"Trying to improve compliance with prophylactic penicillin therapy in children with sickle cell disease","volume":"45","author":"Berkovitch","year":"1998","journal-title":"British Journal of Clinical Pharmacology"},{"issue":"5","key":"10.1002\/14651858.CD003427-BIB8|cit8","first-page":"196","article-title":"A trial of chemoprophylaxis in sickle cell anaemia. Preliminary communication.","volume":"39","author":"Lewthwaite","year":"1962","journal-title":"East African Medical Journal"},{"issue":"1","key":"10.1002\/14651858.CD003427-BIB9|cit9","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/S0022-3476(84)80582-X","article-title":"Effect of penicillin prophylaxis on nasopharyngeal colonization with Streptococcus pneumoniae in children with sickle cell anemia","volume":"104","author":"Anglin","year":"1984","journal-title":"Journal of Pediatrics"},{"issue":"3","key":"10.1002\/14651858.CD003427-BIB10|cit10","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1097\/00006454-200003000-00003","article-title":"Efficacy, safety and immunogenicity of hepavalent pneumococcal conjugated vaccine in children. Northern California Kaiser Permanente Vaccine Study Center Group","volume":"19","author":"Black","year":"2000","journal-title":"Pediatric Infectious Disease Journal"},{"key":"10.1002\/14651858.CD003427-BIB11|cit11","volume-title":"British National Formulary","year":"2001"},{"issue":"8","key":"10.1002\/14651858.CD003427-BIB12|cit12","first-page":"912","article-title":"The escalating problem of antimicrobial resistance in Streptococcus pneumoniae","volume":"146","author":"Chesney","year":"1992","journal-title":"American Journal of Diseases of Children"},{"issue":"6783","key":"10.1002\/14651858.CD003427-BIB13|cit13","doi-asserted-by":"crossref","first-page":"989","DOI":"10.1136\/bmj.302.6783.989","article-title":"Penicillin prophylaxis in children with sickle cell disease in Brent","volume":"302","author":"Cummins","year":"1991","journal-title":"BMJ"},{"issue":"7109","key":"10.1002\/14651858.CD003427-BIB14|cit14","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1136\/bmj.315.7109.656","article-title":"The management of patients with sickle cell disease","volume":"315","author":"Davies","year":"1997","journal-title":"BMJ"},{"issue":"1","key":"10.1002\/14651858.CD003427-BIB15|cit15","doi-asserted-by":"crossref","DOI":"10.1002\/14651858.CD003885.pub2","article-title":"Pneumococcal vaccines for sickle cell disease (Cochrane Review)","author":"Davies","year":"2004","journal-title":"Cochrane Database of Systematic Reviews"},{"issue":"4","key":"10.1002\/14651858.CD003427-BIB16|cit16","doi-asserted-by":"crossref","first-page":"E7","DOI":"10.1542\/peds.99.4.e7","article-title":"Nasopharyngeal carriage of penicillin resistant Streptococcus Pneumoniae in children with sickle cell disease","volume":"99","author":"Daw","year":"1997","journal-title":"Pediatrics"},{"issue":"4","key":"10.1002\/14651858.CD003427-BIB17|cit17","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1542\/peds.69.4.452","article-title":"Serum penicillin concentrations after intramuscular administration of benzathine penicillin G in children","volume":"69","author":"Ginsburg","year":"1982","journal-title":"Pediatrics"},{"issue":"4","key":"10.1002\/14651858.CD003427-BIB18|cit18","doi-asserted-by":"crossref","first-page":"860","DOI":"10.1046\/j.1365-2141.1999.01275.x","article-title":"Mapping the prevalence of sickle cell and beta thalassaemia in England: estimating and validating ethnic-specific rates","volume":"104","author":"Hickman","year":"1999","journal-title":"British Journal of Haematology"},{"issue":"14","key":"10.1002\/14651858.CD003427-BIB19|cit19","doi-asserted-by":"crossref","first-page":"1341","DOI":"10.1056\/NEJMoa035060","article-title":"A trial of 9-valent pneumococcal conjugate vaccine in children with and those without HIV infection","volume":"349","author":"Klugman","year":"2003","journal-title":"New England Journal of Medicine"},{"issue":"7020","key":"10.1002\/14651858.CD003427-BIB20|cit20","doi-asserted-by":"crossref","first-page":"1600","DOI":"10.1136\/bmj.311.7020.1600","article-title":"Improved survival in homozygous sickle cell disease: lessons from a cohort study","volume":"311","author":"Lee","year":"1995","journal-title":"BMJ"},{"issue":"1","key":"10.1002\/14651858.CD003427-BIB21|cit21","doi-asserted-by":"crossref","DOI":"10.1002\/14651858.CD001913","article-title":"Neonatal screening for sickle cell disease (Cochrane Review)","author":"Lees","year":"2000","journal-title":"Cochrane Database of Systematic Reviews"},{"issue":"3","key":"10.1002\/14651858.CD003427-BIB22|cit22","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1542\/peds.84.3.500","article-title":"Mortality in children and adolescents with sickle cell disease. Co-operative Study of Sickle Cell Disease","volume":"84","author":"Leikin","year":"1989","journal-title":"Pediatrics"},{"issue":"6","key":"10.1002\/14651858.CD003427-BIB23|cit23","first-page":"543","article-title":"Clinicopathologic characteristics of septicaemia in sickle cell disease","volume":"136","author":"Lobel","year":"1982","journal-title":"American Journal of Diseases of Children"},{"issue":"1","key":"10.1002\/14651858.CD003427-BIB24|cit24","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1592\/phco.20.1.110.34660","article-title":"Duration of penicillin prophylaxis in sickle cell anemia: issues and controversies","volume":"20","author":"Pai","year":"2000","journal-title":"Pharmacotherapy"},{"issue":"23","key":"10.1002\/14651858.CD003427-BIB25|cit25","doi-asserted-by":"crossref","first-page":"1639","DOI":"10.1056\/NEJM199406093302303","article-title":"Mortality in sickle cell disease: life expectancy and risk factors for early death","volume":"330","author":"Platt","year":"1994","journal-title":"New England Journal of Medicine"},{"issue":"18","key":"10.1002\/14651858.CD003427-BIB26|cit26","doi-asserted-by":"crossref","first-page":"1006","DOI":"10.1056\/NEJM196605052741806","article-title":"Pneumococcal meningitis in sickle-cell anemia","volume":"274","author":"Robinson","year":"1966","journal-title":"The New England Journal of Medicine"},{"issue":"13","key":"10.1002\/14651858.CD003427-BIB27|cit27","doi-asserted-by":"crossref","first-page":"1729","DOI":"10.1001\/jama.285.13.1729","article-title":"Epidemiology of invasive Streptococcus pneumoniae infections in the United States, 1995-1998. Opportunities for prevention in the conjugate vaccine era.","volume":"285","author":"Robinson","year":"2001","journal-title":"JAMA"},{"issue":"5","key":"10.1002\/14651858.CD003427-BIB28|cit28","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1001\/jama.1995.03520290060030","article-title":"Empirical evidence of bias. Dimensions of methodological quality associated with estimates of treatment effects in controlled trials","volume":"273","author":"Schulz","year":"1995","journal-title":"JAMA"},{"key":"10.1002\/14651858.CD003427-BIB29|cit29","first-page":"153","article-title":"The immune system","volume-title":"Sickle Cell Disease","author":"Serjeant","year":"2001"},{"issue":"4","key":"10.1002\/14651858.CD003427-BIB30|cit30","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1097\/00043426-199707000-00011","article-title":"Influence of penicillin prophylaxis on antimicrobial resistance in nasopharyngeal S. pneumoniae among children with sickle cell anemia. The Ancillary Nasopharyngeal Culture Study of Prophylactic Penicillin Study II","volume":"19","author":"Woods","year":"1997","journal-title":"Journal of Pediatric Hematology\/Oncology"},{"issue":"4","key":"10.1002\/14651858.CD003427-BIB31|cit31","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1016\/S0022-3476(86)80216-5","article-title":"Bacteremia in sickle hemoglobinopathies","volume":"109","author":"Zarkowsky","year":"1986","journal-title":"Journal of Pediatrics"}],"container-title":["Cochrane Database of Systematic Reviews"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cochranelibrary.com\/cdsr\/doi\/10.1002\/14651858.CD003427\/epdf\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,11]],"date-time":"2024-01-11T13:50:30Z","timestamp":1704981030000},"score":1,"resource":{"primary":{"URL":"https:\/\/doi.wiley.com\/10.1002\/14651858.CD003427"}},"subtitle":[],"editor":[{"given":"Ceri","family":"Hirst","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2002,7,22]]},"references-count":31,"URL":"https:\/\/doi.org\/10.1002\/14651858.cd003427","relation":{},"subject":[],"published":{"date-parts":[[2002,7,22]]}}}