{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T06:02:23Z","timestamp":1791352943069,"version":"4.3.1"},"update-to":[{"DOI":"10.1002\/14651858.cd003717.pub2","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2014,5,9]],"date-time":"2014-05-09T00:00:00Z","timestamp":1399593600000}}],"reference-count":127,"publisher":"Wiley","issue":"5","content-domain":{"domain":["wiley.com","cochranelibrary.com"],"crossmark-restriction":true},"short-container-title":[],"DOI":"10.1002\/14651858.cd003717.pub3","type":"journal-article","created":{"date-parts":[[2014,5,9]],"date-time":"2014-05-09T02:38:19Z","timestamp":1399603099000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":61,"title":["Audio-visual presentation of information for informed consent for participation in clinical trials"],"prefix":"10.1002","volume":"2014","author":[{"given":"Anneliese","family":"Synnot","sequence":"first","affiliation":[{"name":"La Trobe University; Centre for Health Communication and Participation, School of Public Health and Human Biosciences; Bundoora Vic Australia 3086"},{"name":"School of Public Health and Human Biosciences, La Trobe University; Cochrane Consumers and Communication Review Group; Bundoora Victoria Australia 3086"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rebecca","family":"Ryan","sequence":"additional","affiliation":[{"name":"La Trobe University; Centre for Health Communication and Participation, School of Public Health and Human Biosciences; Bundoora Vic Australia 3086"},{"name":"School of Public Health and Human Biosciences, La Trobe University; Cochrane Consumers and Communication Review Group; Bundoora Victoria Australia 3086"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Megan","family":"Prictor","sequence":"additional","affiliation":[{"name":"School of Public Health and Human Biosciences, La Trobe University; Cochrane Consumers and Communication Review Group; Bundoora Victoria Australia 3086"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deirdre","family":"Fetherstonhaugh","sequence":"additional","affiliation":[{"name":"La Trobe University; Australian Centre for Evidence Based Aged Care (ACEBAC); Bundoora Victoria Australia 3086"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barbara","family":"Parker","sequence":"additional","affiliation":[{"name":"La Trobe University; Australian Institute for Primary Care & Ageing, Faculty of Health Sciences; Bundoora Victoria Australia 3086"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,5,9]]},"reference":[{"issue":"6","key":"10.1002\/14651858.CD003717.pub3-BIB0001|cit1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.2307\/3564285","article-title":"Improving informed consent: a comparison of four consent tools","volume":"25","author":"Agre","year":"2003","journal-title":"IRB: Ethics and Human Research"},{"key":"10.1002\/14651858.CD003717.pub3-BIB0002|cit2","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1007\/BF01044628","article-title":"Information disclosure, subject understanding, and informed consent in psychiatric research","volume":"12","author":"Benson","year":"1988","journal-title":"Law and Human Behavior"},{"key":"10.1002\/14651858.CD003717.pub3-BIB0003|cit3","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/S0738-3991(03)00162-9","article-title":"The effect of format modifications and reading comprehension on recall of informed consent information by low-income parents: a comparison of print, video, and computer-based presentations","volume":"53","author":"Campbell","year":"2004","journal-title":"Patient Education and Counseling"},{"key":"10.1002\/14651858.CD003717.pub3-BIB0004|cit4","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/j.schres.2012.08.001","article-title":"Preliminary study of a web-based tool for enhancing the informed consent process in schizophrenia research","volume":"141","author":"Harmell","year":"2012","journal-title":"Schizophrenia Research"},{"key":"10.1002\/14651858.CD003717.pub3-BIB0005|cit5","doi-asserted-by":"crossref","unstructured":"Hitchcock-Bryan S Hoffner B Joffe S Powell M Parker C Wolanski A Entering a Clinical Trial: Is It Right For You?- A randomized study of the clinical trials video and its impact on the informed consent process [Abstract No. 9072] Journal of Clinical Oncology : ASCO annual meeting proceedings 2007 510","DOI":"10.1200\/jco.2007.25.18_suppl.9072"},{"key":"10.1002\/14651858.CD003717.pub3-BIB0006|cit6","doi-asserted-by":"crossref","first-page":"1877","DOI":"10.1002\/cncr.26438","article-title":"\"Entering a Clinical Trial: Is it Right For You?\" A randomized study of the clinical trials video and its impact on the informed consent process","volume":"118","author":"Hoffner","year":"2012","journal-title":"Cancer"},{"key":"10.1002\/14651858.CD003717.pub3-BIB0007|cit7","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1038\/sj.bjc.6603943","article-title":"A randomised controlled study of an audiovisual patient information intervention on informed consent and recruitment to cancer clinical trials","volume":"97","author":"Hutchison","year":"2007","journal-title":"British Journal of Cancer"},{"key":"10.1002\/14651858.CD003717.pub3-BIB0008|cit8","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1111\/j.1365-2354.2006.00732.x","article-title":"Patient understanding of research: developing and testing of a new questionnaire","volume":"16","author":"Hutchison","year":"2007","journal-title":"European Journal of Cancer Care"},{"key":"10.1002\/14651858.CD003717.pub3-BIB0009|cit9","doi-asserted-by":"crossref","first-page":"2047","DOI":"10.1111\/j.1365-2702.2006.01758.x","article-title":"The process of developing audiovisual patient information: challenges and opportunities","volume":"16","author":"Hutchison","year":"2007","journal-title":"Journal of Clinical Nursing"},{"key":"10.1002\/14651858.CD003717.pub3-BIB0010|cit10","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1093\/schbul\/sbm148","article-title":"Multimedia consent for research in people with schizophrenia and normal subjects: a randomized controlled trial","volume":"35","author":"Jeste","year":"2009","journal-title":"Schizophrenia Bulletin"},{"key":"10.1002\/14651858.CD003717.pub3-BIB0011|cit11","doi-asserted-by":"crossref","first-page":"388","DOI":"10.5694\/j.1326-5377.2010.tb03561.x","article-title":"Improving communication when seeking informed consent: a randomised controlled study of a computer-based method for providing information to prospective clinical trial participants","volume":"192","author":"Karunaratne","year":"2010","journal-title":"Medical Journal of Australia"},{"key":"10.1002\/14651858.CD003717.pub3-BIB0012|cit12","first-page":"521","article-title":"A randomised trial of a CD-ROM educational intervention for advanced cancer patients enrolling in early phase trials","volume":"22","author":"Daugherty","year":"2003","journal-title":"Proceedings of the American Society for Clinical Oncology"},{"issue":"14(S)","key":"10.1002\/14651858.CD003717.pub3-BIB0013|cit13","first-page":"6054","article-title":"Effects of a CD-ROM educational intervention (CD) on prognosis (prog) understanding among advanced cancer patients (acp) enrolling in early phase clinical trials","volume":"22","author":"Hlubocky","year":"2004","journal-title":"Journal of Clinical Oncology, 2004 ASCO Annual Meeting Proceedings"},{"issue":"3","key":"10.1002\/14651858.CD003717.pub3-BIB0014|cit14","first-page":"1","article-title":"An intervention to improve cancer patients' understanding of early-phase clinical trials","volume":"31","author":"Kass","year":"2009","journal-title":"IRB: Ethics & Human Research"},{"key":"10.1002\/14651858.CD003717.pub3-BIB0015|cit15","unstructured":"Klein DW Schartz HA Instructional Strategies to Improve Informed Consent in Healthcare Research: Pilot Study of Interactivity and Multimedia Paper presented at the American Educational Research Association National Conference Vancouver, Canada April 2012"},{"issue":"2","key":"10.1002\/14651858.CD003717.pub3-BIB0016|cit16","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1097\/JGP.0b013e31802dd379","article-title":"Comparison of two enhanced consent procedures for patients with mild Alzheimer disease or mild cognitive impairment","volume":"15","author":"Mittal","year":"2007","journal-title":"American Journal of Geriatric Psychiatry"},{"issue":"4","key":"10.1002\/14651858.CD003717.pub3-BIB0017|cit17","first-page":"263","article-title":"Using instructive videotapes to increase patient comprehension of informed consent","volume":"4","author":"Norris","year":"1990","journal-title":"Journal of Clinical Research & Pharmacoepidemiology"},{"key":"10.1002\/14651858.CD003717.pub3-BIB0018|cit18","doi-asserted-by":"crossref","first-page":"917","DOI":"10.1542\/peds.2010-3283","article-title":"Novel approach to parental permission and child assent for research: improving comprehension","volume":"127","author":"O'Lonergan","year":"2011","journal-title":"Pediatrics"},{"key":"10.1002\/14651858.CD003717.pub3-BIB0019|cit19","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1007\/s00520-006-0199-2","article-title":"The impact of an educational DVD on cancer patients considering participation in a phase I clinical trial","volume":"15","author":"Strevel","year":"2007","journal-title":"Supportive Care in Cancer"},{"key":"10.1002\/14651858.CD003717.pub3-BIB0020|cit20","doi-asserted-by":"crossref","unstructured":"Weston J Downes J Hannah M Evaluating the benefits of patient video during the informed consent process Controlled Clinical Trials 1995 73S (abstract)","DOI":"10.1016\/0197-2456(95)90481-J"},{"issue":"3","key":"10.1002\/14651858.CD003717.pub3-BIB0021|cit21","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1016\/S0738-3991(96)00968-8","article-title":"Evaluating the benefits of a patient information video during the informed consent process","volume":"30","author":"Weston","year":"1997","journal-title":"Patient Education & Counseling"},{"key":"10.1002\/14651858.CD003717.pub3-BIB0022|cit22","author":"Mintz","journal-title":"cited in Agre 2003"},{"key":"10.1002\/14651858.CD003717.pub3-BIB0023|cit23","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1016\/S0920-9964(03)80235-9","article-title":"A videotape intervention to enhance the informed consent process for patients participating in clinical research trial","volume":"60","author":"Wirshing","year":"2003","journal-title":"Schizophrenia Research"},{"issue":"1","key":"10.1002\/14651858.CD003717.pub3-BIB0024|cit24","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1176\/appi.ajp.162.1.186","article-title":"A videotape intervention to enhance the informed consent process for medical and psychiatric treatment research","volume":"162","author":"Wirshing","year":"2005","journal-title":"American Journal of Psychiatry"},{"issue":"25","key":"10.1002\/14651858.CD003717.pub3-BIB0025|cit25","doi-asserted-by":"crossref","first-page":"2741","DOI":"10.1001\/jama.1978.03290250045026","article-title":"Videotape aids informed consent decision","volume":"240","author":"Barbour","year":"1978","journal-title":"JAMA"},{"issue":"9315","key":"10.1002\/14651858.CD003717.pub3-BIB0026|cit26","doi-asserted-by":"crossref","first-page":"1406","DOI":"10.1016\/S0140-6736(02)08361-7","article-title":"Audiovisual documentation of oral consent: a new method of informed consent for illiterate populations","volume":"359","author":"Benitez","year":"2002","journal-title":"Lancet"},{"issue":"12","key":"10.1002\/14651858.CD003717.pub3-BIB0027|cit27","doi-asserted-by":"crossref","first-page":"1331","DOI":"10.1016\/0277-9536(85)90388-0","article-title":"Informed consent in psychiatric research: preliminary findings from an ongoing investigation","volume":"20","author":"Benson","year":"1985","journal-title":"Social Science & Medicine."},{"key":"10.1002\/14651858.CD003717.pub3-BIB0028|cit28","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1016\/j.pec.2009.02.007","article-title":"Using computer agents to explain medical documents to patients with low health literacy","volume":"75","author":"Bickmore","year":"2009","journal-title":"Patient Education and Counseling"},{"key":"10.1002\/14651858.CD003717.pub3-BIB0029|cit29","unstructured":"National Institute of General Medical Sciences Informed consent template for genetic repository research available at: http:\/\/ccr.coriell.org\/Sections\/Support\/NIGMS\/Model.aspx?PgId=216 n.d. [2009]"},{"key":"10.1002\/14651858.CD003717.pub3-BIB0030|cit30","first-page":"6","article-title":"Impact of a clinical trials information handbook on patient knowledge, perceptions, and likelihood of participation","volume":"30","author":"Campbell","year":"2008","journal-title":"IRB: Ethics & Human Research"},{"issue":"1","key":"10.1002\/14651858.CD003717.pub3-BIB0031|cit31","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/S0277-9536(03)00162-X","article-title":"Can a brief video intervention improve breast cancer clinical trial knowledge and beliefs?","volume":"58","author":"Curbow","year":"2004","journal-title":"Social Science & Medicine"},{"key":"10.1002\/14651858.CD003717.pub3-BIB0032|cit32","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1089\/tmj.2005.11.84","article-title":"Use of videoconferencing for depression research: enrollment, retention, and patient satisfaction","volume":"11","author":"Dobscha","year":"2005","journal-title":"Telemedicine Journal & E Health"},{"key":"10.1002\/14651858.CD003717.pub3-BIB0033|cit33","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1097\/JTO.0b013e31815e8bb2","article-title":"An educational video to increase clinical trials enrollment among lung cancer patients","volume":"3","author":"Du","year":"2008","journal-title":"Journal of Thoracic Oncology"},{"issue":"1","key":"10.1002\/14651858.CD003717.pub3-BIB0034|cit34","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/0197-2456(89)90020-2","article-title":"Implementation of a multicomponent process to obtain informed consent in the Diabetes Control and Complications Trial","volume":"10","author":"Dunbar","year":"1989","journal-title":"Controlled Clinical Trials"},{"key":"10.1002\/14651858.CD003717.pub3-BIB0035|cit35","doi-asserted-by":"crossref","first-page":"872","DOI":"10.1016\/j.jclinepi.2010.11.008","article-title":"Preconsent education about research processes improved African Americans' willingness to participate in clinical research","volume":"64","author":"Dunlop","year":"2011","journal-title":"Journal of Clinical Epidemiology"},{"issue":"2","key":"10.1002\/14651858.CD003717.pub3-BIB0036|cit36","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1097\/00019442-200203000-00005","article-title":"Improving understanding of research consent in middle-aged and elderly patients with psychotic disorders","volume":"10","author":"Dunn","year":"2002","journal-title":"American Journal of Geriatric Psychiatry"},{"issue":"11","key":"10.1002\/14651858.CD003717.pub3-BIB0037|cit37","doi-asserted-by":"crossref","first-page":"1911","DOI":"10.1176\/appi.ajp.158.11.1911","article-title":"Enhancing comprehension of consent for research in older patients with psychosis: a randomised study of a novel consent procedure","volume":"158","author":"Dunn","year":"2001","journal-title":"American Journal of Psychiatry"},{"issue":"13","key":"10.1002\/14651858.CD003717.pub3-BIB0038|cit38","doi-asserted-by":"crossref","first-page":"1593","DOI":"10.1001\/jama.292.13.1593","article-title":"Interventions to improve research participants' understanding in informed consent for research: a systematic review","volume":"292","author":"Flory","year":"2004","journal-title":"JAMA"},{"issue":"4","key":"10.1002\/14651858.CD003717.pub3-BIB0039|cit39","first-page":"330","article-title":"Evaluation of a video-supplement to informed consent: injection drug users and preventive HIV vaccine efficacy trials","volume":"9","author":"Fureman","year":"1997","journal-title":"AIDS Education & Prevention"},{"key":"10.1002\/14651858.CD003717.pub3-BIB0040|cit40","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1016\/j.cct.2011.11.010","article-title":"Effectiveness of an informational video method to improve enrollment and retention of a pediatric cohort","volume":"33","author":"Gesualdo","year":"2012","journal-title":"Contemporary Clinical Trials"},{"key":"10.1002\/14651858.CD003717.pub3-BIB0041|cit41","doi-asserted-by":"crossref","first-page":"780","DOI":"10.1016\/j.ahj.2011.07.006","article-title":"Effect of informed consent format on patient anxiety, knowledge, and satisfaction","volume":"162","author":"Goldberger","year":"2011","journal-title":"American Heart Journal"},{"key":"10.1002\/14651858.CD003717.pub3-BIB0042|cit42","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1002\/pon.1070","article-title":"Standardized audiotape versus recorded consultation to enhance informed consent to a clinical trial in breast oncology","volume":"16","author":"Hack","year":"2007","journal-title":"Psycho-Oncology"},{"key":"10.1002\/14651858.CD003717.pub3-BIB0043|cit43","first-page":"268","article-title":"Studying the effectiveness of videos in conveying medical information regarding breast cancer risks and the Study of Tamoxifen and Raloxifene (STAR) trial","volume":"69","author":"Harzstark","year":"2001","journal-title":"Breast Cancer Research & Treatment"},{"key":"10.1002\/14651858.CD003717.pub3-BIB0044|cit44","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1002\/pbc.22411","article-title":"A feasibility trial of a video intervention to improve informed consent for parents of children with leukemia","volume":"55","author":"Hazen","year":"2010","journal-title":"Pediatric Blood & Cancer"},{"key":"10.1002\/14651858.CD003717.pub3-BIB0045|cit45","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1177\/0193945906292558","article-title":"Video recruitment of non-English-speaking participants","volume":"29","author":"Hendrickson","year":"2007","journal-title":"Western Journal of Nursing Research"},{"key":"10.1002\/14651858.CD003717.pub3-BIB0046|cit46","first-page":"1","article-title":"Reformed consent: adapting to new media and research participant preferences","volume":"31","author":"Henry","year":"2009","journal-title":"IRB: Ethics & Human Research"},{"key":"10.1002\/14651858.CD003717.pub3-BIB0047|cit47","doi-asserted-by":"crossref","first-page":"1","DOI":"10.2307\/3564119","article-title":"Empirical research on informed consent with the cognitively impaired","volume":"25","author":"Hougham","year":"2003","journal-title":"IRB: Human Ethics and Research (Supplement)"},{"key":"10.1002\/14651858.CD003717.pub3-BIB0048|cit48","doi-asserted-by":"crossref","first-page":"174-8","DOI":"10.1016\/j.brs.2009.01.003","article-title":"Challenges in consenting subjects for studies with brain stimulation: feasibility of multimedia video use during the informed consent process","volume":"2","author":"Hultgren","year":"2009","journal-title":"Brain Stimulation"},{"key":"10.1002\/14651858.CD003717.pub3-BIB0049|cit49","first-page":"419","article-title":"Influence of an educational videotape on attitudes toward participating in cohort studies--results of a randomized controlled trial","volume":"54","author":"Ishii","year":"2007","journal-title":"Japanese journal of public health"},{"key":"10.1002\/14651858.CD003717.pub3-BIB0050|cit50","doi-asserted-by":"crossref","first-page":"2516","DOI":"10.1200\/JCO.2011.39.5186","article-title":"Effects of a brief multimedia psychoeducational intervention on the attitudes and interest of patients with cancer regarding clinical trial participation: a multicenter randomized controlled trial","volume":"30","author":"Jacobsen","year":"2012","journal-title":"Journal of Clinical Oncology"},{"issue":"3","key":"10.1002\/14651858.CD003717.pub3-BIB0051|cit51","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1136\/jamia.1998.0050245","article-title":"The use of multimedia in the informed consent process","volume":"5","author":"Jimison","year":"1998","journal-title":"Journal of the American Medical Informatics Association"},{"issue":"5","key":"10.1002\/14651858.CD003717.pub3-BIB0052|cit52","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1097\/01.qai.0000229998.59869.05","article-title":"The use of an educational video during informed consent in an HIV clinical trial in Haiti","volume":"42","author":"Joseph","year":"2006","journal-title":"Journal of Acquired Immune Deficiency Syndromes"},{"key":"10.1002\/14651858.CD003717.pub3-BIB0053|cit53","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1080\/10572250802100451","article-title":"Keeping users at the center: developing a multimedia interface for informed consent","volume":"17","author":"Kim","year":"2008","journal-title":"Technical Communication Quarterly"},{"key":"10.1002\/14651858.CD003717.pub3-BIB0054|cit54","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/0738-3991(94)00705-Q","article-title":"Presenting clinical trial information: a comparison of methods","volume":"25","author":"Llewellyn-Thomas","year":"1995","journal-title":"Patient Education & Counseling"},{"key":"10.1002\/14651858.CD003717.pub3-BIB0055|cit55","first-page":"9","article-title":"Clarity and appeal of a multimedia informed consent tool for biobanking","volume":"34","author":"McGraw SA. Wood-Nutter","year":"2012","journal-title":"IRB: Ethics & Human Research"},{"key":"10.1002\/14651858.CD003717.pub3-BIB0056|cit56","doi-asserted-by":"crossref","first-page":"990","DOI":"10.1136\/bjo.2006.092650","article-title":"Effects of presentation method on the understanding of informed consent","volume":"90","author":"Moseley","year":"2006","journal-title":"British Journal of Ophthalmology"},{"key":"10.1002\/14651858.CD003717.pub3-BIB0057|cit57","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1093\/schbul\/sbi066","article-title":"Using a brief intervention to improve decisional capacity in schizophrenia research","volume":"32","author":"Moser","year":"2006","journal-title":"Schizophrenia Bulletin"},{"issue":"6","key":"10.1002\/14651858.CD003717.pub3-BIB0058|cit58","first-page":"1","article-title":"Effectiveness of multimedia aids to enhance comprehension of research consent information: a systematic review","volume":"34","author":"Palmer","year":"2012 (Nov\/Dec)","journal-title":"IRB: Ethics & Human Research"},{"key":"10.1002\/14651858.CD003717.pub3-BIB0059|cit59","doi-asserted-by":"crossref","unstructured":"Quinn G Wells K Antonia T Antolino P Lopez N Gonzalez L Abstract A30: Evaluating Spanish audiovisual materials about cancer clinical trials: improving awareness among Hispanic patients and families Cancer Epidemiology Biomarkers and Prevention 2011 np 10.1158\/1055-9965.DISP-11-A30","DOI":"10.1158\/1055-9965.DISP-11-A30"},{"key":"10.1002\/14651858.CD003717.pub3-BIB0060|cit60","doi-asserted-by":"crossref","first-page":"941","DOI":"10.1111\/j.1464-410X.2007.06822_5.x","article-title":"Informed consent: are we deluding ourselves? A randomized controlled study","volume":"99","author":"Sahai","year":"2007","journal-title":"BJU International"},{"key":"10.1002\/14651858.CD003717.pub3-BIB0061|cit61","doi-asserted-by":"crossref","first-page":"1065","DOI":"10.1136\/bmj.293.6554.1065","article-title":"Randomised comparison of procedures for obtaining informed consent in clinical trials of treatment for cancer","volume":"293","author":"Simes","year":"1986","journal-title":"BMJ"},{"key":"10.1002\/14651858.CD003717.pub3-BIB0062|cit62","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1016\/0738-3991(94)90069-8","article-title":"Effects of two formats of informed consent on knowledge among persons with advanced HIV disease in a clinical trial of didanosine","volume":"24","author":"Tindall","year":"1994","journal-title":"Patient Education and Counseling"},{"issue":"1","key":"10.1002\/14651858.CD003717.pub3-BIB0063|cit63","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1207\/s15327019eb1501_3","article-title":"How informed is online informed consent?","volume":"15","author":"Varnhagen","year":"2005","journal-title":"Ethics and Behaviour"},{"key":"10.1002\/14651858.CD003717.pub3-BIB0064|cit64","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1016\/j.pec.2012.03.011","article-title":"Development of a cancer clinical trials multi-media intervention: Clinical trials: Are they right for you?","volume":"88","author":"Wells","year":"2012","journal-title":"Patient Education and Counseling"},{"issue":"3","key":"10.1002\/14651858.CD003717.pub3-BIB0065|cit65","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1016\/S0277-9536(99)00477-3","article-title":"Information presentation and decisions to enter clinical trials: a hypothetical trial of hormone replacement therapy","volume":"51","author":"Wragg","year":"2000","journal-title":"Social Science & Medicine"},{"key":"10.1002\/14651858.CD003717.pub3-BIB0066|cit66","unstructured":"Hougham GW Sachs GA Danner D Mintz J Patterson M Roberts L University of California at Los Angeles study Cited in Hougham 2003: study not cited by name, authors, only by affiliation"},{"key":"10.1002\/14651858.CD003717.pub3-BIB0067|cit67","doi-asserted-by":"crossref","first-page":"e58603","DOI":"10.1371\/journal.pone.0058603","article-title":"Interactive informed consent: randomized comparison with paper consents","volume":"8","author":"Rowbotham","year":"2013","journal-title":"PLoS ONE"},{"key":"10.1002\/14651858.CD003717.pub3-BIB0068|cit68","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.cct.2013.05.011","article-title":"Development and pilot testing of a video-assisted informed consent process","volume":"36","author":"Sonne","year":"2013","journal-title":"Contemporary Clinical Trials"},{"issue":"5","key":"10.1002\/14651858.CD003717.pub3-BIB0069|cit69","doi-asserted-by":"crossref","first-page":"S11","DOI":"10.2307\/3564117","article-title":"Improving informed consent: the medium is not the message","volume":"25","author":"Agre","year":"2003","journal-title":"IRB: Ethics and Human Research (Supplement)"},{"key":"10.1002\/14651858.CD003717.pub3-BIB0070|cit70","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1007\/s11910-010-0123-5","article-title":"Consent in impaired populations","volume":"10","author":"Appelbaum","year":"2010","journal-title":"Current Neurology and Neuroscience Reports"},{"issue":"7","key":"10.1002\/14651858.CD003717.pub3-BIB0071|cit71","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1038\/sj.jp.7211142","article-title":"Neonatal research and the validity of informed consent obtained in the perinatal period","volume":"24","author":"Ballard","year":"2004","journal-title":"Journal of Perinatology"},{"key":"10.1002\/14651858.CD003717.pub3-BIB0072|cit72","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1525\/jer.2007.2.4.69","article-title":"Education level, primary language, and comprehension of the informed consent process","volume":"2","author":"Breese","year":"2007","journal-title":"Journal of Empirical Research on Human Research Ethics"},{"issue":"4","key":"10.1002\/14651858.CD003717.pub3-BIB0073|cit73","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD003319.pub2","article-title":"Continuous quality improvement: effects on professional practice and healthcare outcomes","author":"Brennan","year":"2009","journal-title":"Cochrane Database of Systematic Reviews"},{"key":"10.1002\/14651858.CD003717.pub3-BIB0074|cit74","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1097\/00126334-200405010-00009","article-title":"Determinants of enrollment in a preventive HIV vaccine trial: hypothetical versus actual willingness and barriers to participation","volume":"36","author":"Buchbinder","year":"2004","journal-title":"Journal of Acquired Immune Deficiency Syndromes"},{"issue":"12","key":"10.1002\/14651858.CD003717.pub3-BIB0075|cit75","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD008273.pub2","article-title":"Information interventions for orienting patients and their carers to cancer care facilities","author":"Chan","year":"2011","journal-title":"Cochrane Database of Systematic Reviews"},{"issue":"2","key":"10.1002\/14651858.CD003717.pub3-BIB0076|cit76","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1136\/adc.2005.076141","article-title":"Parental consent in paediatric clinical research","volume":"91","author":"Chappuy","year":"2006","journal-title":"Archives of Disease in Childhood"},{"key":"10.1002\/14651858.CD003717.pub3-BIB0077|cit77","doi-asserted-by":"crossref","first-page":"800","DOI":"10.1136\/adc.2009.180695","article-title":"Parental comprehension and satisfaction in informed consent in paediatric clinical trials: a prospective study on childhood leukaemia","volume":"95","author":"Chappuy","year":"2010","journal-title":"Archives of Disease in Childhood"},{"key":"10.1002\/14651858.CD003717.pub3-BIB0078|cit78","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1111\/j.1547-5069.2007.00180.x","article-title":"Improving participant comprehension in the informed consent process","volume":"39","author":"Cohn","year":"2007","journal-title":"Journal of Nursing Scholarship"},{"key":"10.1002\/14651858.CD003717.pub3-BIB0079|cit79","unstructured":"Dunn LB Lindamer LA Schneiderman LJ Jeste DV A novel, computer-based enhancement of informed consent in older patients with psychotic disorders 14th Annual Meeting of the American Association for Geriatric Psychiatry San Francisco, CA, USA"},{"issue":"8","key":"10.1002\/14651858.CD003717.pub3-BIB0080|cit80","doi-asserted-by":"crossref","first-page":"1323","DOI":"10.1176\/ajp.2006.163.8.1323","article-title":"Assessing decisional capacity for clinical research or treatment: a review of instruments","volume":"163","author":"Dunn","year":"2006","journal-title":"American Journal of Psychiatry"},{"issue":"2","key":"10.1002\/14651858.CD003717.pub3-BIB0081|cit81","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD001865.pub3","article-title":"Personalised risk communication for informed decision making about taking screening tests","author":"Edwards","year":"2013","journal-title":"Cochrane Database of Systematic Reviews"},{"key":"10.1002\/14651858.CD003717.pub3-BIB0082|cit82","doi-asserted-by":"publisher","first-page":"895","DOI":"10.1016\/j.cct.2012.04.005","article-title":"Randomization to standard and concise informed consent forms: development of evidence-based consent practices","volume":"33","author":"Enama","year":"2012","journal-title":"Contemporary Clinical Trials"},{"key":"10.1002\/14651858.CD003717.pub3-BIB0083|cit83","doi-asserted-by":"crossref","first-page":"919","DOI":"10.1016\/j.jamcollsurg.2010.02.049","article-title":"Predictors of comprehension during surgical informed consent","volume":"210","author":"Fink","year":"2010","journal-title":"Journal of the American College of Surgeons"},{"issue":"4","key":"10.1002\/14651858.CD003717.pub3-BIB0084|cit84","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1016\/j.ijnurstu.2006.03.014","article-title":"The quality of parental consent for research with children: a prospective repeated measure self-report survey","volume":"44","author":"Franck","year":"2007","journal-title":"International Journal of Nursing Studies"},{"key":"10.1002\/14651858.CD003717.pub3-BIB0085|cit85","unstructured":"Brozek J Oxman A Sch\u00fcnemann H GRADEpro 2008"},{"key":"10.1002\/14651858.CD003717.pub3-BIB0086|cit86","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1191\/1740774506cn133oa","article-title":"Consumer involvement in consent document development: a multicenter cluster randomized trial to assess study participants' understanding","volume":"3","author":"Guarino","year":"2006","journal-title":"Clinical Trials"},{"key":"10.1002\/14651858.CD003717.pub3-BIB0087|cit87","doi-asserted-by":"crossref","first-page":"924","DOI":"10.1136\/bmj.39489.470347.AD","article-title":"Rating quality of evidence and strength of recommendations GRADE: an emerging consensus on rating quality of evidence and strength of recommendations","volume":"336","author":"Guyatt","year":"2008","journal-title":"BMJ"},{"issue":"12","key":"10.1002\/14651858.CD003717.pub3-BIB0088|cit88","doi-asserted-by":"crossref","first-page":"1647","DOI":"10.1016\/0277-9536(95)00058-F","article-title":"Parental perceptions and attitudes about informed consent in clinical research involving children","volume":"41","author":"Harth","year":"1995","journal-title":"Social Science & Medicine"},{"key":"10.1002\/14651858.CD003717.pub3-BIB0089|cit89","doi-asserted-by":"crossref","first-page":"2096","DOI":"10.1016\/S0959-8049(00)00191-X","article-title":"Information and communication in the context of a clinical trial","volume":"36","author":"Hietanen","year":"2000","journal-title":"European Journal of Cancer"},{"key":"10.1002\/14651858.CD003717.pub3-BIB0090|cit90","unstructured":"Higgins JPT Green S Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 [updated March 2011] The Cochrane Collaboration, available from www.cochrane-handbook.org 2011"},{"key":"10.1002\/14651858.CD003717.pub3-BIB0091|cit91","unstructured":"Higgins JPT Deeks JJ Altman DG (editors) Chapter 16: Special topics in statistics Higgins JPT Green S Cochrane Handbook for Systematic Reviews of Interventions"},{"key":"10.1002\/14651858.CD003717.pub3-BIB0092|cit92","doi-asserted-by":"crossref","first-page":"1772","DOI":"10.1016\/S0140-6736(01)06805-2","article-title":"Quality of informed consent in cancer clinical trials: a cross-sectional survey","volume":"358","author":"Joffe","year":"2001","journal-title":"Lancet"},{"issue":"2","key":"10.1002\/14651858.CD003717.pub3-BIB0093|cit93","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1093\/jnci\/93.2.139","article-title":"Quality of informed consent: a new measure of understanding among research subjects","volume":"93","author":"Joffe","year":"2001","journal-title":"Journal of the National Cancer Institute"},{"issue":"7","key":"10.1002\/14651858.CD003717.pub3-BIB0094|cit94","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD009445.pub2","article-title":"Interventions to promote informed consent for patients undergoing surgical and other invasive healthcare procedures","author":"Kinnersley","year":"2013","journal-title":"Cochrane Database of Systematic Reviews"},{"issue":"3","key":"10.1002\/14651858.CD003717.pub3-BIB0095|cit95","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1191\/1740774506cn150oa","article-title":"Problems in comprehension of informed consent in rural and peri-urban Mali, West Africa","volume":"3","author":"Krosin","year":"2006","journal-title":"Clinical Trials"},{"issue":"3","key":"10.1002\/14651858.CD003717.pub3-BIB0096|cit96","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/S0197-2456(00)00048-9","article-title":"A randomized trial assessing the impact of written information on outpatients' knowlege about and attitude towards randomized clinical trials","volume":"21","author":"Kruse","year":"2000","journal-title":"Controlled Clinical Trials"},{"issue":"10","key":"10.1002\/14651858.CD003717.pub3-BIB0097|cit97","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1097\/00043426-200310000-00009","article-title":"Clinical trials in pediatric cancer: parental perspectives on informed consent","volume":"25","author":"Kupst","year":"2003","journal-title":"Journal of Pediatric Hematology and Oncology"},{"key":"10.1002\/14651858.CD003717.pub3-BIB0098|cit98","doi-asserted-by":"crossref","first-page":"872","DOI":"10.1002\/j.1875-9114.1996.tb03004.x","article-title":"The Deacones Informed Consent Comprehension Test: an assessment tool for clinical research subjects","volume":"16","author":"Miller","year":"1996","journal-title":"Pharmacotherapy"},{"issue":"3","key":"10.1002\/14651858.CD003717.pub3-BIB0099|cit99","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1093\/jpepsy\/jsi032","article-title":"Clinician-parent communication during informed consent for pediatric leukemia trials","volume":"30","author":"Miller","year":"2005","journal-title":"Journal of Pediatric Psychology"},{"issue":"12","key":"10.1002\/14651858.CD003717.pub3-BIB0100|cit100","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1136\/jme.2004.009910","article-title":"Informed consent and participant perceptions of influenza vaccine trials in South Africa","volume":"31","author":"Moodley","year":"2005","journal-title":"Journal of Medical Ethics"},{"key":"10.1002\/14651858.CD003717.pub3-BIB0101|cit101","volume-title":"National Statement on Ethical Conduct in Research","author":"National Health and Medical Research Council","year":"2007"},{"key":"10.1002\/14651858.CD003717.pub3-BIB0102|cit102","unstructured":"NIH Clinical Research Trials and You http:\/\/www.nih.gov\/health\/clinicaltrials\/basics.htm 2012"},{"issue":"3","key":"10.1002\/14651858.CD003717.pub3-BIB0103|cit103","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD004563.pub2","article-title":"Methods of consumer involvement in developing healthcare policy and research, clinical practice guidelines and patient information material","author":"Nilsen","year":"2006","journal-title":"Cochrane Database of Systematic Reviews"},{"issue":"28","key":"10.1002\/14651858.CD003717.pub3-BIB0104|cit104","doi-asserted-by":"publisher","DOI":"10.1186\/1472-6939-14-28","article-title":"Improving understanding in the research informed consent process: a systematic review of 54 interventions in randomised controlled trials","volume":"14","author":"Nishimura","year":"2013","journal-title":"BMC Medical Ethics"},{"key":"10.1002\/14651858.CD003717.pub3-BIB0105|cit105","doi-asserted-by":"crossref","first-page":"726","DOI":"10.1001\/archpsyc.62.7.726","article-title":"Assessment of capacity to consent to research among older persons with schizophrenia, Alzheimer's disease or diabetes mellitus","volume":"62","author":"Palmer","year":"2005","journal-title":"Archives of General Psychiatry"},{"issue":"4","key":"10.1002\/14651858.CD003717.pub3-BIB0106|cit106","first-page":"815","article-title":"Are subjects satisfied with the informed consent process? A survey of research participants","volume":"30","author":"Pope","year":"2003","journal-title":"Journal of Rheumatology"},{"key":"10.1002\/14651858.CD003717.pub3-BIB0107|cit107","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1046\/j.1369-6513.2001.00138.x","article-title":"Information about screening - is it to achieve high uptake or to ensure informed choice?","volume":"4","author":"Raffle","year":"2001","journal-title":"Health Expectations"},{"key":"10.1002\/14651858.CD003717.pub3-BIB0108|cit108","doi-asserted-by":"crossref","unstructured":"Robinson EJ Kerr CEP Stevens AJ Lilford RJ Braunholtz DA Edwards SJ Lay public's understanding of equipoise and randomisation in randomised controlled trials Health Technology Assessment 2005","DOI":"10.3310\/hta9080"},{"issue":"3","key":"10.1002\/14651858.CD003717.pub3-BIB0109|cit109","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1177\/104345429100800304","article-title":"Informed consent for treatment of childhood cancer: factors affecting parents' decision making","volume":"8","author":"Ruccione","year":"1991","journal-title":"Journal of Pediatric Oncology Nursing"},{"key":"10.1002\/14651858.CD003717.pub3-BIB0110|cit110","unstructured":"Ryan R Hill S Prictor M McKenzie J Cochrane Consumers and Communication Review Group Study Quality Guide http:\/\/cccrg.cochrane.org\/author-resources (last accessed 5 Sep 2013) May 2013"},{"issue":"7","key":"10.1002\/14651858.CD003717.pub3-BIB0111|cit111","doi-asserted-by":"crossref","first-page":"988","DOI":"10.1136\/jnnp.74.7.988","article-title":"Informed consent in trials for neurological emergencies: the example of subarachnoid haemorrhage","volume":"74","author":"Schats","year":"2003","journal-title":"Journal of Neurology Neurosurgery and Psychiatry"},{"key":"10.1002\/14651858.CD003717.pub3-BIB0112|cit112","article-title":"Chapter 12: Interpreting results and drawing conclusions","volume-title":"Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 (updated March 2011)","author":"Sch\u00fcnemann","year":"2011"},{"key":"10.1002\/14651858.CD003717.pub3-BIB0113|cit113","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1080\/10810730.2011.604391","article-title":"Interventions for individuals with low health literacy: a systematic review","volume":"16","author":"Sheridan","year":"2011","journal-title":"Journal of Health Communication: International Perspectives"},{"issue":"3","key":"10.1002\/14651858.CD003717.pub3-BIB0114|cit114","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1002\/1097-0142(20010801)92:3<691::AID-CNCR1372>3.0.CO;2-4","article-title":"Informed consent for pediatric leukemia research: clinician perspectives","volume":"92","author":"Simon","year":"2001","journal-title":"Cancer"},{"issue":"1","key":"10.1002\/14651858.CD003717.pub3-BIB0115|cit115","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD001431.pub4","article-title":"Decision aids for people facing health treatment or screening decisions","author":"Stacey","year":"2014","journal-title":"Cochrane Database of Systematic Reviews"},{"issue":"11","key":"10.1002\/14651858.CD003717.pub3-BIB0116|cit116","doi-asserted-by":"crossref","first-page":"788","DOI":"10.1111\/j.1445-2197.1998.tb04678.x","article-title":"Informed consent: how much information is enough?","volume":"68","author":"Stanley","year":"1998","journal-title":"Australian and New Zealand Journal of Surgery"},{"key":"10.1002\/14651858.CD003717.pub3-BIB0117|cit117","doi-asserted-by":"crossref","first-page":"664","DOI":"10.1136\/jme.2004.011064","article-title":"\"Hello hello - it's English I speak!\": a qualitative exploration of patients' understanding of the science of clinical trials","volume":"31","author":"Stead","year":"2005","journal-title":"Journal of Medical Ethics"},{"issue":"1-2","key":"10.1002\/14651858.CD003717.pub3-BIB0118|cit118","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1016\/j.pec.2005.09.006","article-title":"Understanding the decisions of cancer clinical trial participants to enter research studies: factors associated with informed consent, patient satisfaction, and decisional regret","volume":"63","author":"Stryker","year":"2006","journal-title":"Patient Education and Counseling"},{"key":"10.1002\/14651858.CD003717.pub3-BIB0119|cit119","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1111\/j.1532-5415.1998.tb02477.x","article-title":"Getting meaningful informed consent from older adults: a structured literature review of empirical research","volume":"46","author":"Sugarman","year":"1998","journal-title":"Journal of the American Geriatrics Society"},{"issue":"3","key":"10.1002\/14651858.CD003717.pub3-BIB0120|cit120","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1097\/00000542-200303000-00005","article-title":"Do they understand? (part I): parental consent for children participating in clinical anesthesia and surgery research","volume":"98","author":"Tait","year":"2003","journal-title":"Anesthesiology"},{"issue":"4","key":"10.1002\/14651858.CD003717.pub3-BIB0121|cit121","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.MR000013.pub5","article-title":"Strategies to improve recruitment to randomised controlled trials","author":"Treweek","year":"2010","journal-title":"Cochrane Database of Systematic Reviews"},{"key":"10.1002\/14651858.CD003717.pub3-BIB0122|cit122","doi-asserted-by":"crossref","first-page":"E13","DOI":"10.1186\/1472-6939-7-13","article-title":"Consenting of the vulnerable: the informed consent procedure in advanced cancer patients in Mexico","volume":"7","author":"Ver\u00e1stegui","year":"2006","journal-title":"BMC Medical Ethics"},{"key":"10.1002\/14651858.CD003717.pub3-BIB0123|cit123","unstructured":"World Health Organisation International Clinical Trials Registry Platform (ICTRP) http:\/\/www.who.int\/ictrp\/en\/ 2013"},{"issue":"9361","key":"10.1002\/14651858.CD003717.pub3-BIB0124|cit124","doi-asserted-by":"crossref","first-page":"918","DOI":"10.1016\/S0140-6736(03)12773-0","article-title":"Informed consent during the clinical emergency of acute myocardial infarction (HERO-2 consent substudy): a prospective observational study","volume":"361","author":"Williams","year":"2003","journal-title":"Lancet"},{"key":"10.1002\/14651858.CD003717.pub3-BIB0125|cit125","unstructured":"World Medical Association Declaration of Helsinki. Ethical Principles for Medical Research Involving Human Subjects Adopted by the 18th WMA General Assembly Helsinki, Finland, June 1964 and amended by the 29th WMA General Assembly, Tokyo, Japan, October 1975, 35th WMA General Assembly, Venice, Italy, October 1983, 41st WMA General Assembly, Hong Kong, September 1989, 48th WMA General Assembly, Somerset West, Republic of South Africa, October 1996, 52nd WMA General Assembly, Edinburgh, Scotland, October 2000, 53rd WMA General Assembly, Washington, DC, USA, October\u00a02002, 55th WMA General Assembly, Tokyo, Japan, October\u00a02004 and 59th WMA General Assembly, Seoul, Korea, October 2008"},{"issue":"3","key":"10.1002\/14651858.CD003717.pub3-BIB0126|cit126","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD003717","article-title":"Informational video for potential participants of clinical studies used in the process of seeking informed consent","author":"McLaughlin","year":"2002","journal-title":"Cochrane Database of Systematic Reviews"},{"issue":"3","key":"10.1002\/14651858.CD003717.pub3-BIB0127|cit127","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD003717.pub2","article-title":"Audio-visual presentation of information for informed consent for participation in clinical trials","author":"Ryan","year":"2008","journal-title":"Cochrane Database of Systematic Reviews"}],"container-title":["Cochrane Database of Systematic Reviews"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/onlinelibrary.wiley.com\/wol1\/doi\/10.1002\/14651858.CD003717.pub3\/fullpdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,12,19]],"date-time":"2023-12-19T10:10:34Z","timestamp":1702980634000},"score":1,"resource":{"primary":{"URL":"http:\/\/doi.wiley.com\/10.1002\/14651858.CD003717.pub3"}},"subtitle":[],"editor":[{"name":"Cochrane Consumers and Communication Group","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2014,5,9]]},"references-count":127,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2014,5]]}},"URL":"https:\/\/doi.org\/10.1002\/14651858.cd003717.pub3","relation":{},"ISSN":["1465-1858"],"issn-type":[{"value":"1465-1858","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,5,9]]}}}