{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,4]],"date-time":"2025-10-04T08:18:53Z","timestamp":1759565933987},"reference-count":44,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2002,10,21]],"date-time":"2002-10-21T00:00:00Z","timestamp":1035158400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"},{"start":{"date-parts":[[2002,10,21]],"date-time":"2002-10-21T00:00:00Z","timestamp":1035158400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions"}],"content-domain":{"domain":["wiley.com","cochranelibrary.com"],"crossmark-restriction":true},"short-container-title":[],"DOI":"10.1002\/14651858.cd003867","type":"journal-article","created":{"date-parts":[[2003,11,21]],"date-time":"2003-11-21T17:14:00Z","timestamp":1069434840000},"update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Single dose dipyrone for acute renal colic pain"],"prefix":"10.1002","volume":"2017","author":[{"given":"Jayne","family":"Edwards","sequence":"first","affiliation":[{"name":"UK Cochrane Centre; Training Team; National Institute for Health Research Summertown Pavilion, Middle Way Oxford UK OX2 7LG"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fuensanta","family":"Meseguer","sequence":"additional","affiliation":[{"name":"Hospital Reina Sof\u00eda; Reanimaci\u00f3n y Tratamiento del Dolor; General Universitario de Murcia Murcia Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Clara","family":"Faura","sequence":"additional","affiliation":[{"name":"Universidad Miguel Hernandaz; Instituto de Neurosciences; Campus San Juan Alicante Spain 03550"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R Andrew","family":"Moore","sequence":"additional","affiliation":[{"name":"University of Oxford; Pain Research and Nuffield Department of Clinical Neurosciences (Nuffield Division of Anaesthetics); Pain Research Unit Churchill Hospital Oxford Oxfordshire UK OX3 7LE"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Henry J","family":"McQuay","sequence":"additional","affiliation":[{"name":"University of Oxford; Pain Research and Nuffield Department of Clinical Neurosciences (Nuffield Division of Anaesthetics); Pain Research Unit Churchill Hospital Oxford Oxfordshire UK OX3 7LE"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sheena","family":"Derry","sequence":"additional","affiliation":[{"name":"University of Oxford; Pain Research and Nuffield Department of Clinical Neurosciences (Nuffield Division of Anaesthetics); Pain Research Unit Churchill Hospital Oxford Oxfordshire UK OX3 7LE"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2002,10,21]]},"reference":[{"key":"10.1002\/14651858.CD003867-BIB0001|cit1","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1007\/BF00279966","article-title":"Comparative study of the efficacy of dipyrone, diclofenac sodium and pethidine in acute renal colic","volume":"40","author":"Arnau","year":"1991","journal-title":"Eur J Clin Pharmacol"},{"issue":"2","key":"10.1002\/14651858.CD003867-BIB0002|cit2","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1177\/039156038505200222","volume":"52","author":"Comeri","year":"1985","journal-title":"Urologia"},{"issue":"9","key":"10.1002\/14651858.CD003867-BIB0003|cit3","first-page":"575","article-title":"Nifedipine in the treatment of renal colic","volume":"8","author":"Lloret","year":"1986","journal-title":"Methods Find Exp Clin Pharmacol"},{"issue":"6","key":"10.1002\/14651858.CD003867-BIB0004|cit4","first-page":"1119","article-title":"Treatment of renal colic with dipyrone. A double-blind comparison trial with hyoscine alone or combined with dipyrone","volume":"42","author":"Lloret","year":"1987","journal-title":"Current Therapeutic Research Clinical and Experimental"},{"issue":"9","key":"10.1002\/14651858.CD003867-BIB0005|cit5","first-page":"763","article-title":"A double-blind study of the analgesic efficacy in kidney colic of the combination of dipyrone and spasmolytic with ketorolac trometamol","volume":"46","author":"Martin Carrasco","year":"1993","journal-title":"Arch Esp Urol"},{"issue":"5","key":"10.1002\/14651858.CD003867-BIB0006|cit6","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1007\/BF00544249","article-title":"Diclofenac versus dipyrone in acute renal colic: a double-blind controlled trial","volume":"33","author":"Miralles","year":"1987","journal-title":"European Journal of Clinical Pharmacology"},{"issue":"8","key":"10.1002\/14651858.CD003867-BIB0007|cit7","first-page":"773","article-title":"Flurbiprofen: Alternative treatment in renal colic pain","volume":"45","author":"Mora-Durban","year":"1992","journal-title":"Arch Esp de Urol"},{"key":"10.1002\/14651858.CD003867-BIB0008|cit8","first-page":"867","article-title":"Flurbiprofen vs dipyrone combined with hyoscine: the analgesic efficacy in renal colic","volume":"48","author":"Mora-Durban","year":"1995","journal-title":"Arch Esp Urol"},{"issue":"2","key":"10.1002\/14651858.CD003867-BIB0009|cit9","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1007\/BF00192733","article-title":"Comparison of the onset and duration of the analgesic effect of dipyrone, 1 or 2 g, by the intramuscular or intravenous route, in acute renal colic","volume":"48","author":"Muriel Villoria","year":"1995","journal-title":"European Journal of Clinical Pharmacology"},{"issue":"4","key":"10.1002\/14651858.CD003867-BIB0010|cit10","first-page":"361","article-title":"Intramuscular diclofenac sodium versus intravenous Baralgin in the treatment of renal colic","volume":"24","author":"Sanahuja","year":"1990","journal-title":"Dicp Ann Pharmacother"},{"issue":"3","key":"10.1002\/14651858.CD003867-BIB0011|cit11","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1007\/BF00192278","article-title":"Double-blind study with dipyrone versus tramadol and butylscopolamine in acute renal colic pain","volume":"12","author":"Stankov","year":"1994","journal-title":"World J Urol"},{"issue":"3","key":"10.1002\/14651858.CD003867-BIB0012|cit12","first-page":"181","volume":"86","author":"Arico","year":"1983","journal-title":"F Med (Br)"},{"issue":"10","key":"10.1002\/14651858.CD003867-BIB0013|cit13","first-page":"569","article-title":"Comparative study of Baralgan and hyoscine-N-methyl bromide in the treatment of intestinal and renal colicy pain","volume":"69","author":"Benyajati","year":"1986","journal-title":"J Med Assoc Thai"},{"issue":"3","key":"10.1002\/14651858.CD003867-BIB0014|cit14","first-page":"253","article-title":"Medical therapy of ureteral colic. A comparative clinical study of 3 spasmolytics, 1 of which is combined with an analgesic","volume":"36","author":"Borelli","year":"1984","journal-title":"Minerva Urol Nefrol"},{"issue":"4","key":"10.1002\/14651858.CD003867-BIB0015|cit15","first-page":"185","article-title":"Treatment of renal colic","volume":"40","author":"Campero","year":"1993","journal-title":"Bol Hosp San Juan de Dios"},{"key":"10.1002\/14651858.CD003867-BIB0016|cit16","doi-asserted-by":"crossref","first-page":"602","DOI":"10.1111\/j.1464-410X.1990.tb07190.x","article-title":"Treatment of renal colic by prostaglandin synthetase inhibitors and avafortan (analgesic antispasmodic)","volume":"66","author":"Sherif","year":"1990","journal-title":"Br J Urol"},{"issue":"4","key":"10.1002\/14651858.CD003867-BIB0017|cit17","first-page":"295","article-title":"Use of indomethacin and metamizole administered intravenously in renal colic. Comparative study","volume":"35","author":"Galassi","year":"1983","journal-title":"Minerva Urol"},{"key":"10.1002\/14651858.CD003867-BIB0018|cit18","first-page":"295","article-title":"Oral diclofenac sodium in the treatment of acute renal colic. A prospective randomized study","volume":"27","author":"Indudhara","year":"1990","journal-title":"Clin Trials J"},{"issue":"5-6","key":"10.1002\/14651858.CD003867-BIB0019|cit19","first-page":"959","article-title":"Effect of the combination of 2.5 g of dipyrone with 0.1 mg of fenpiverinium bromide in the treatment of renal colic","volume":"85","author":"Kalil","year":"1982","journal-title":"Folha Med"},{"issue":"5-6","key":"10.1002\/14651858.CD003867-BIB0020|cit20","first-page":"197","article-title":"Intravenous indomethacin in the treatment of ureteric colic. A clinical multicentre study with pethidine and metamizol as the control preparations","volume":"15","author":"Lehtonen","year":"1983","journal-title":"Ann Clin Res"},{"issue":"6","key":"10.1002\/14651858.CD003867-BIB0021|cit21","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1185\/03007999109111506","article-title":"A multi-centre comparative study of diclofenac sodium and a dipyrone\/spasmolytic combination, and a single-centre comparative study of diclofenac sodium and pethidine in renal colic patients in India","volume":"12","author":"Marthak","year":"1991","journal-title":"Curr Med Res Opin"},{"issue":"7","key":"10.1002\/14651858.CD003867-BIB0022|cit22","first-page":"465","article-title":"Efficacy of two different intramuscular doses of dipyrone in acute renal colic","volume":"15","author":"Muriel","year":"1993","journal-title":"Methods Find Exp Clin Pharmacol"},{"issue":"2","key":"10.1002\/14651858.CD003867-BIB0023|cit23","first-page":"94","article-title":"Comparison of the effects of ceruletide with respect to dipyrone and to a single infusion of physiologic serum in patients with pain due to nephritic colic","volume":"37","author":"Pardo","year":"1984","journal-title":"Arch Esp Urol"},{"key":"10.1002\/14651858.CD003867-BIB0024|cit24","first-page":"2125","article-title":"Treatment of renal colic with ketoprofen","volume":"13","author":"Pourrat","year":"1984","journal-title":"Presse Med"},{"issue":"2","key":"10.1002\/14651858.CD003867-BIB0025|cit25","first-page":"103","article-title":"Tramadol versus metimazole in alleviating pain in ureteral colic","volume":"28","author":"Primus","year":"1989","journal-title":"Urologe A"},{"key":"10.1002\/14651858.CD003867-BIB0026|cit26","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1007\/BF00278592","article-title":"Metamizol: reassessment of its therapeutic role","volume":"38","author":"Arrellano","year":"1990","journal-title":"European Journal of Clinical Pharmacology"},{"key":"10.1002\/14651858.CD003867-BIB0027|cit27","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1152\/physrev.1987.67.1.67","article-title":"Peripheral and spinal mechanisms of nociception","volume":"67","author":"Besson","year":"1987","journal-title":"Physiol Rev"},{"key":"10.1002\/14651858.CD003867-BIB0028|cit28","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/S0304-3959(97)00005-5","article-title":"The visual analogue pain intensity scale: what is moderate pain in millimetres?","volume":"72","author":"Collins","year":"1997","journal-title":"Pain"},{"key":"10.1002\/14651858.CD003867-BIB0029|cit29","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/S0304-3959(00)00435-8","article-title":"Seeking a simple measure of analgesia for mega-trials: is a single global assessment good enough?","volume":"91","author":"Collins","year":"2001","journal-title":"Pain"},{"key":"10.1002\/14651858.CD003867-BIB0030|cit30","first-page":"117","article-title":"Single-dose analgesic studies: the upside and downside of assay sensitivity. In: Max MB, Portenoy RK, Laska EM Eds.","volume":"18","author":"Cooper","year":"1991","journal-title":"The design of analgesic clinical trials - Advances in Pain Research and Therapy"},{"key":"10.1002\/14651858.CD003867-BIB0031|cit31","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1007\/BF00279966","article-title":"Comparative study of the efficacy of dipyrone, diclofenac sodium and pethidine in acute renal colic","volume":"40","author":"Collaborative Group of the Spanish Society of Clinical Pharmacology","year":"1991","journal-title":"Eur J Clin Pharmcol"},{"key":"10.1002\/14651858.CD003867-BIB0032|cit32","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1007\/BF01990960","article-title":"Differential effects of dipyrone, ibuprofen and paracetamol on experimentally-induced pain in man","volume":"35","author":"Foster","year":"1992","journal-title":"Agents and Actions"},{"issue":"13","key":"10.1002\/14651858.CD003867-BIB0033|cit33","doi-asserted-by":"crossref","first-page":"1749","DOI":"10.1001\/jama.1986.03380130077032","article-title":"Risks of Agranulocytosis and Aplastic Anemia - A first report of their relation to drug use with special reference to anaglesics","volume":"256","author":"International Agranulocytosis and Aplastic Anemia Study","year":"1986","journal-title":"JAMA"},{"key":"10.1002\/14651858.CD003867-BIB0034|cit34","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1016\/0304-3959(96)03033-3","article-title":"Developing a database of published reports of randomised clinical trials in pain research","volume":"66","author":"Jadad","year":"1996","journal-title":"Pain"},{"key":"10.1002\/14651858.CD003867-BIB0035|cit35","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0197-2456(95)00134-4","article-title":"Assessing the quality of reports of randomized clinical trials: is blinding necessary?","volume":"17","author":"Jadad","year":"1996","journal-title":"Controlled Clinical Trials"},{"issue":"6","key":"10.1002\/14651858.CD003867-BIB0036|cit36","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1016\/0895-4356(88)90069-8","article-title":"The International Agranulocytosis and Aplastic Anemia Study (IAAAS)","volume":"41","author":"Kramer","year":"1988","journal-title":"J Clin Epidemiol"},{"key":"10.1002\/14651858.CD003867-BIB0037|cit37","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/0304-3959(96)03032-1","article-title":"Deriving dichotomous outcome measures from continuous data in randomised controlled trials of analgesics","volume":"66","author":"Moore","year":"1996","journal-title":"Pain"},{"key":"10.1002\/14651858.CD003867-BIB0038|cit38","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/S0304-3959(96)03251-4","article-title":"Deriving dichotomous outcome measures from continuous data in randomised controlled trials of analgesics: Verification from independent data","volume":"69","author":"Moore","year":"1997","journal-title":"Pain"},{"key":"10.1002\/14651858.CD003867-BIB0039|cit39","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1016\/S0304-3959(96)03306-4","article-title":"Deriving dichotomous outcome measures from continuous data in randomised controlled trials of analgesics: Use of pain intensity and visual analogue scales","volume":"69","author":"Moore","year":"1997","journal-title":"Pain"},{"issue":"3","key":"10.1002\/14651858.CD003867-BIB0040|cit40","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/S0304-3959(98)00140-7","article-title":"Size is everything--large amounts of information are needed to overcome random effects in estimating direction and magnitude of treatment effects","volume":"78","author":"Moore","year":"1998","journal-title":"Pain"},{"key":"10.1002\/14651858.CD003867-BIB0041|cit41","first-page":"754","volume":"82","author":"Quilez","year":"1984","journal-title":"Med Clin"},{"key":"10.1002\/14651858.CD003867-BIB0042|cit42","volume-title":"Martindale: the extra pharmacopoeia 292-314","volume":"292-314","author":"Reynolds","year":"1993"},{"key":"10.1002\/14651858.CD003867-BIB0043|cit43","doi-asserted-by":"crossref","first-page":"1109","DOI":"10.1152\/jn.1985.54.5.1109","article-title":"Effects of an experimental arthritis on the sensory properties of fine articular afferents units. J Neurophysiol 1985; 54:1109","volume":"54","author":"Schaible","year":"1985","journal-title":"J Neurophysiol"},{"key":"10.1002\/14651858.CD003867-BIB0044|cit44","unstructured":"Victorov I A clinical study of dipyrone (Analgin) in urologic patients The proceedings of the dipyrone symposium, Moscow 1978 Stuttgart Schattauer Verlag 1980"}],"container-title":["Cochrane Database of Systematic Reviews"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full\/10.1002\/14651858.CD003867","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,7,3]],"date-time":"2023-07-03T05:03:03Z","timestamp":1688360583000},"score":1,"resource":{"primary":{"URL":"http:\/\/doi.wiley.com\/10.1002\/14651858.CD003867"}},"subtitle":[],"editor":[{"name":"Cochrane Pain, Palliative and Supportive Care Group","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2002,10,21]]},"references-count":44,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2017,8]]}},"URL":"https:\/\/doi.org\/10.1002\/14651858.cd003867","relation":{},"ISSN":["1465-1858"],"issn-type":[{"type":"electronic","value":"1465-1858"}],"subject":[],"published":{"date-parts":[[2002,10,21]]}}}