{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T06:56:01Z","timestamp":1777359361069,"version":"3.51.4"},"publisher-location":"Chichester, UK","reference-count":43,"publisher":"John Wiley & Sons, Ltd","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"DOI":"10.1002\/14651858.cd003956","type":"reference-entry","created":{"date-parts":[[2003,11,21]],"date-time":"2003-11-21T17:16:55Z","timestamp":1069435015000},"source":"Crossref","is-referenced-by-count":7,"title":["Granulocyte transfusions for neonates with confirmed or suspected sepsis and neutropaenia"],"prefix":"10.1002","author":[{"given":"Mohan","family":"Pammi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Brocklehurst","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2003,10,20]]},"reference":[{"key":"10.1002\/14651858.CD003956-BIB1|cit1","doi-asserted-by":"crossref","first-page":"712","DOI":"10.1542\/peds.80.5.712","article-title":"Buffy coat transfusions in neutropenic neonates with presumed sepsis: A prospective randomized trial","volume":"80","author":"Baley","year":"1987","journal-title":"Pediatrics"},{"key":"10.1002\/14651858.CD003956-BIB2|cit2","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/S0022-3476(05)80445-7","article-title":"Randomized trial of granulocyte transfusions versus intravenous immune globulin therapy for neonatal neutropenia and sepsis","volume":"120","author":"Cairo","year":"1992","journal-title":"Journal of Pediatrics"},{"key":"10.1002\/14651858.CD003956-BIB3|cit3","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1542\/peds.70.1.1","article-title":"Granulocyte transfusions in neonates with bacterial infection, neutropenia and depletion of mature marrow neutrophils","volume":"70","author":"Christensen","year":"1982","journal-title":"Pediatrics"},{"key":"10.1002\/14651858.CD003956-BIB4|cit4","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1542\/peds.79.3.422","article-title":"Buffy coat transfusions in neonates with sepsis and neutrophil storage pool depletion","volume":"79","author":"Wheeler","year":"1987","journal-title":"Pediatrics"},{"key":"10.1002\/14651858.CD003956-BIB5|cit5","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1097\/00006454-198409000-00003","article-title":"Neutrophil storage pool depletion in septic, neutropenic neonates","volume":"3","author":"Wheeler","year":"1984","journal-title":"Pediatric Infectious Disease Journal"},{"key":"10.1002\/14651858.CD003956-BIB6|cit6","doi-asserted-by":"crossref","first-page":"887","DOI":"10.1542\/peds.74.5.887","article-title":"Improved survival of newborns receiving leukocyte transfusions for sepsis","volume":"74","author":"Cairo","year":"1984","journal-title":"Pediatrics"},{"key":"10.1002\/14651858.CD003956-BIB7|cit7","doi-asserted-by":"crossref","first-page":"935","DOI":"10.1016\/S0022-3476(87)80418-3","article-title":"Role of circulating complement and polymorphonuclear leukocyte transfusion in treatment and outcome in critically ill neonates with sepsis","volume":"110","author":"Cairo","year":"1987","journal-title":"Journal of Pediatrics"},{"key":"10.1002\/14651858.CD003956-BIB8|cit8","doi-asserted-by":"crossref","first-page":"1003","DOI":"10.1136\/adc.58.12.1003","article-title":"Polymorphonuclear leucocyte transfusion in neonatal septicaemia","volume":"58","author":"Laing","year":"1983","journal-title":"Archives of Disease in Childhood"},{"key":"10.1002\/14651858.CD003956-BIB9|cit9","first-page":"169 (abstract 1","article-title":"Granulocyte transfusions in very premature infants with sepsis","volume":"14 (part 2)","author":"Laurenti","year":"1980","journal-title":"Pediatric Research"},{"key":"10.1002\/14651858.CD003956-BIB10|cit10","first-page":"709","article-title":"Treatment with granulocyte concentrates in VLBW infants","volume":"32","author":"Laurenti","year":"1979","journal-title":"Acta Pediatrica-Latina"},{"key":"10.1002\/14651858.CD003956-BIB11|cit11","doi-asserted-by":"crossref","first-page":"1424 (abstract","DOI":"10.1203\/00006450-198012000-00095","article-title":"Polymorphonuclear leukocytes (PMN) transfusion for the treatment of neonatal sepsis","volume":"14 (part 2)","author":"Laurenti","year":"1980","journal-title":"Pediatric Research"},{"key":"10.1002\/14651858.CD003956-BIB12|cit12","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1016\/S0095-5108(18)30277-X","article-title":"Neutropenia in the neonate","volume":"22","author":"al-Mulla","year":"1995","journal-title":"Clinics in Perinatology"},{"key":"10.1002\/14651858.CD003956-BIB13|cit13","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1046\/j.1365-2141.2000.01992.x","article-title":"Neutrophil production and function in newborn infants","volume":"110","author":"Carr","year":"2000","journal-title":"British Journal of Haematology"},{"issue":"3","key":"10.1002\/14651858.CD003956-BIB14|cit14","doi-asserted-by":"crossref","DOI":"10.1002\/14651858.CD003066","article-title":"G-CSF and GM-CSF for treating or preventing neonatal infections","author":"Carr","year":"2003","journal-title":"Cochrane Database of Systematic Reviews"},{"key":"10.1002\/14651858.CD003956-BIB15|cit15","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1007\/s00520-002-0394-8","article-title":"Granulocyte transfusions from G-CSF-stimulated donors for the treatment of severe infections in neutropenic pediatric patients with onco-hematological diseases","volume":"11","author":"Cesaro","year":"2003","journal-title":"Support Care Cancer"},{"key":"10.1002\/14651858.CD003956-BIB16|cit16","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1016\/S0891-5520(05)70301-9","article-title":"Granulocyte transfusions: Time for a second look","volume":"10","author":"Chanock","year":"1996","journal-title":"Infectious Disease Clinics of North America"},{"key":"10.1002\/14651858.CD003956-BIB17|cit17","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1046\/j.1365-2141.1997.3023119.x","article-title":"Renewed interest in granulocyte transfusion therapy","volume":"98","author":"Dale","year":"1997","journal-title":"British Journal of Haematology"},{"key":"10.1002\/14651858.CD003956-BIB18|cit18","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1046\/j.1423-0410.2000.79100591.x","article-title":"Granulocyte transfusions: International forum","volume":"79","author":"Engelfriet","year":"2000","journal-title":"Vox Sanguinis"},{"key":"10.1002\/14651858.CD003956-BIB19|cit19","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1097\/00006454-199807000-00004","article-title":"Incidence, presenting features, risk factors and significance of late onset septicemia in very low birth weight infants","volume":"17","author":"Fanaroff","year":"1998","journal-title":"Pediatric Infectious Disease Journal"},{"key":"10.1002\/14651858.CD003956-BIB20|cit20","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1046\/j.1537-2995.1986.26587020115.x","article-title":"Multiple transfusions fail to provoke antibodies against blood cell antigens in human infants","volume":"26","author":"Floss","year":"1985","journal-title":"Transfusion"},{"key":"10.1002\/14651858.CD003956-BIB21|cit21","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1097\/00006454-199011000-00009","article-title":"A ten-year review of neonatal sepsis and comparison with the previous fifty-year experience","volume":"9","author":"Gladstone","year":"1990","journal-title":"Pediatric Infectious Disease Journal"},{"key":"10.1002\/14651858.CD003956-BIB22|cit22","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1001\/jama.1997.03550030047032","article-title":"Maternal infection and cerebral palsy in infants of normal birth weight","volume":"278","author":"Grether","year":"1997","journal-title":"JAMA"},{"key":"10.1002\/14651858.CD003956-BIB23|cit23","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1007\/s00520-005-0910-8","article-title":"Secondary prophylaxis of invasive fungal infections with combination antifungal therapy and G-CSF-mobilized granulocyte transfusions in three children with hematological malignancies","volume":"14","author":"Grigull","year":"2006","journal-title":"Support Care Cancer"},{"key":"10.1002\/14651858.CD003956-BIB24|cit24","doi-asserted-by":"crossref","first-page":"910","DOI":"10.1007\/s00520-006-0041-x","article-title":"G-CSF mobilised granulocyte transfusions in 32 paediatric patients with neutropenic sepsis","volume":"14","author":"Grigull","year":"2006","journal-title":"Support Care Cancer"},{"key":"10.1002\/14651858.CD003956-BIB25|cit25","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1203\/00006450-198710000-00001","article-title":"Biochemical, structural, and functional abnormalities of polymorphonuclear leukocytes in the neonate","volume":"22","author":"Hill","year":"1987","journal-title":"Pediatric Research"},{"key":"10.1002\/14651858.CD003956-BIB26|cit26","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1542\/pir.12-10-298","article-title":"Granulocyte transfusions in neonates","volume":"12","author":"Hill","year":"1991","journal-title":"Pediatrics in Review"},{"key":"10.1002\/14651858.CD003956-BIB27|cit27","doi-asserted-by":"crossref","first-page":"198","DOI":"10.5694\/j.1326-5377.1995.tb126024.x","article-title":"Systemic bacterial and fungal infections in infants in Australian neonatal units","volume":"162","author":"Isaacs","year":"1995","journal-title":"Medical Journal of Australia"},{"key":"10.1002\/14651858.CD003956-BIB28|cit28","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1016\/S0022-3476(81)80556-2","article-title":"Polymorphonuclear leukocyte transfusion for the treatment of sepsis in the newborn infant","volume":"98","author":"Laurenti","year":"1981","journal-title":"Journal of Pediatrics"},{"key":"10.1002\/14651858.CD003956-BIB29|cit29","doi-asserted-by":"crossref","first-page":"612","DOI":"10.1136\/bmj.317.7159.612","article-title":"Antimicrobial resistance: Bacteria on the defence. Resistance stems from misguided efforts to try to sterilise our environment","volume":"317","author":"Levy","year":"1998","journal-title":"BMJ"},{"key":"10.1002\/14651858.CD003956-BIB30|cit30","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/S0022-3476(79)80096-7","article-title":"The neonatal blood count in health and disease. I. Reference values for neutrophilic cells","volume":"95","author":"Manroe","year":"1979","journal-title":"Journal of Pediatrics"},{"key":"10.1002\/14651858.CD003956-BIB31|cit31","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1016\/S0046-8177(83)80022-7","article-title":"Granulocyte antigen systems, antibodies and their clinical significance","volume":"14","author":"McCullough","year":"1983","journal-title":"Human Pathology"},{"key":"10.1002\/14651858.CD003956-BIB32|cit32","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1182\/blood.V67.2.522.522","article-title":"Effect of leukocyte antibodies and HLA matching on the intravascular recovery, survival and tissue localisation of 111-indium granulocytes","volume":"67","author":"McCullough","year":"1986","journal-title":"Blood"},{"key":"10.1002\/14651858.CD003956-BIB33|cit33","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1046\/j.1440-1754.2002.00768.x","article-title":"Sepsis in neonatal intensive care in the late 1990s","volume":"38","author":"Mehr","year":"2002","journal-title":"Journal of Paediatrics and Child Health"},{"key":"10.1002\/14651858.CD003956-BIB34|cit34","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1002\/mpo.2950100504","article-title":"Transfusion of granulocyte rich buffy coats to neutropenic patients","volume":"10","author":"Reiss","year":"1982","journal-title":"Medical and Pediatric Oncology"},{"key":"10.1002\/14651858.CD003956-BIB35|cit35","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1097\/00006454-199305000-00004","article-title":"Hematologic scoring system in early diagnosis of sepsis in neutropenic newborns","volume":"12","author":"Rodwell","year":"1993","journal-title":"Pediatric Infectious Disease Journal"},{"key":"10.1002\/14651858.CD003956-BIB36|cit36","doi-asserted-by":"crossref","first-page":"1909","DOI":"10.1111\/j.1537-2995.2006.00996.x","article-title":"Safety and efficacy of therapeutic early onset granulocyte transfusions in pediatric patients with neutropenia and severe infections","volume":"46","author":"Sachs","year":"2006","journal-title":"Transfusion"},{"key":"10.1002\/14651858.CD003956-BIB37|cit37","doi-asserted-by":"crossref","first-page":"508","DOI":"10.1542\/peds.76.4.508","article-title":"Immunologic follow-up of infants treated with granulocyte transfusion for neonatal sepsis","volume":"76","author":"Stegagno","year":"1985","journal-title":"Pediatrics"},{"key":"10.1002\/14651858.CD003956-BIB38|cit38","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1016\/S0022-3476(96)70192-0","article-title":"Early-onset sepsis in very low birth weight neonates: a report from the National Institute of Child Health and Human Development Neonatal Research Network","volume":"129","author":"Stoll","year":"1996","journal-title":"Journal of Pediatrics"},{"key":"10.1002\/14651858.CD003956-BIB39|cit39","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/S0022-3476(96)70191-9","article-title":"Late-onset sepsis in very low birth weight neonates: a report from the National Institute of Child Health Development Neonatal Research Network","volume":"129","author":"Stoll","year":"1996","journal-title":"Journal of Pediatrics"},{"key":"10.1002\/14651858.CD003956-BIB40|cit40","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1056\/NEJMoa012657","article-title":"Changes in pathogens causing early-onset sepsis in very-low-birth-weight infants","volume":"347","author":"Stoll","year":"2002","journal-title":"New England Journal of Medicine"},{"key":"10.1002\/14651858.CD003956-BIB41|cit41","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/(SICI)1098-1101(1996)11:1<1::AID-JCA1>3.0.CO;2-F","article-title":"Meta-analysis of clinical studies of the efficacy of granulocyte transfusions in the treatment of bacterial sepsis","volume":"11","author":"Vamvakas","year":"1996","journal-title":"Journal of Clinical Apheresis"},{"key":"10.1002\/14651858.CD003956-BIB42|cit42","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1017\/S0012162200000670","article-title":"Perinatal infection is an important risk factor for cerebral palsy in very low birth weight infants","volume":"42","author":"Wheater","year":"2000","journal-title":"Developmental Medicine and Child Neurology"},{"issue":"4","key":"10.1002\/14651858.CD003956-BIB43|cit43","article-title":"Granulocyte transfusions for neonates with confirmed or suspected sepsis and neutropaenia","author":"Mohan","year":"2003","journal-title":"Cochrane Database of Systematic Reviews"}],"updated-by":[{"DOI":"10.1002\/14651858.cd003956.pub2","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2011,10,5]],"date-time":"2011-10-05T00:00:00Z","timestamp":1317772800000}}],"container-title":["Cochrane Database of Systematic Reviews"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cochranelibrary.com\/cdsr\/doi\/10.1002\/14651858.CD003956\/epdf\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,27]],"date-time":"2023-04-27T10:17:05Z","timestamp":1682590625000},"score":1,"resource":{"primary":{"URL":"https:\/\/doi.wiley.com\/10.1002\/14651858.CD003956"}},"subtitle":[],"editor":[{"given":"Mohan","family":"Pammi","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2003,10,20]]},"references-count":43,"URL":"https:\/\/doi.org\/10.1002\/14651858.cd003956","relation":{"new_version":[{"id-type":"doi","id":"10.1002\/14651858.CD003956.pub2","asserted-by":"object"}]},"subject":[],"published":{"date-parts":[[2003,10,20]]}}}