{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T06:50:41Z","timestamp":1792047041786,"version":"4.4.0"},"update-to":[{"DOI":"10.1002\/14651858.cd004503","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2003,10,20]],"date-time":"2003-10-20T00:00:00Z","timestamp":1066608000000}}],"reference-count":32,"publisher":"Wiley","issue":"1","content-domain":{"domain":["wiley.com","cochranelibrary.com"],"crossmark-restriction":true},"short-container-title":[],"DOI":"10.1002\/14651858.cd004503.pub2","type":"journal-article","created":{"date-parts":[[2004,10,14]],"date-time":"2004-10-14T10:08:51Z","timestamp":1097748531000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":25,"title":["Long versus short inspiratory times in neonates receiving mechanical ventilation"],"prefix":"10.1002","volume":"2010","author":[{"given":"Camille Omar Farouk","family":"Kamlin","sequence":"first","affiliation":[{"name":"Royal Women's Hospital; Department of Neonatology; Gratton Street Carlton Victoria Australia 3053"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter G","family":"Davis","sequence":"additional","affiliation":[{"name":"Royal Women's Hospital; Department of Paediatrics; 20 Flemington Rd Parkville Victoria Australia 3052"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2003,10,20]]},"reference":[{"key":"10.1002\/14651858.CD004503.pub2-BIB0001|cit1","doi-asserted-by":"crossref","first-page":"834","DOI":"10.1136\/adc.64.6.834","article-title":"Randomised controlled trial of two methods of weaning from high frequency positive pressure ventilation","volume":"64","author":"Greenough","year":"1989","journal-title":"Archives of Disease in Childhood"},{"key":"10.1002\/14651858.CD004503.pub2-BIB0002|cit2","doi-asserted-by":"crossref","first-page":"957","DOI":"10.1016\/S0022-3476(81)80604-X","article-title":"Prospective clinical comparison of two methods for mechanical ventilation of neonates: Rapid rate and short inspiratory time versus slow rate and long inspiratory time","volume":"98","author":"Heicher","year":"1981","journal-title":"Journal of Pediatrics"},{"key":"10.1002\/14651858.CD004503.pub2-BIB0003|cit3","doi-asserted-by":"crossref","first-page":"770","DOI":"10.1136\/adc.66.7_Spec_No.770","article-title":"Multicentre randomised controlled trial of high frequency positive pressure ventilation. Oxford Region Controlled Trial of Artificial Ventilation OCTAVE Study Group","volume":"66","year":"1991","journal-title":"Archives of Disease in Childhood"},{"key":"10.1002\/14651858.CD004503.pub2-BIB0004|cit4","doi-asserted-by":"crossref","first-page":"904","DOI":"10.1007\/BF01954127","article-title":"Decreased incidence of extra-alveolar air leakage or death prior to air leakage in high versus low rate positive pressure ventilation: results of a randomised seven-centre trial in preterm infants","volume":"151","author":"Pohlandt","year":"1992","journal-title":"European Journal of Pediatrics"},{"key":"10.1002\/14651858.CD004503.pub2-BIB0005|cit5","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1001\/archpedi.1980.04490010031011","article-title":"Hyaline membrane disease - A controlled study of inspiratory to expiratory ratio in its manaagement by ventilator","volume":"134","author":"Spahr","year":"1980","journal-title":"American Journal of Diseases of Children"},{"key":"10.1002\/14651858.CD004503.pub2-BIB0006|cit6","first-page":"344A","article-title":"One second inspiratory time improves lung mechanics in preterm infants who are ventilator dependent post respiratory distress syndrome","volume":"37","author":"Nilmeier","year":"1995","journal-title":"Pediatric Research"},{"key":"10.1002\/14651858.CD004503.pub2-BIB0007|cit7","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/S0140-6736(68)92348-9","article-title":"Mechanical ventilation in newborn infants with respiratory failure","volume":"2","author":"Adamson","year":"1968","journal-title":"Lancet"},{"key":"10.1002\/14651858.CD004503.pub2-BIB0008|cit8","doi-asserted-by":"crossref","first-page":"F161","DOI":"10.1136\/fn.71.3.F161","article-title":"Computerised determination of spontaneous inspiratory and expiratory times in premature neonates during intermittent positive pressure ventilation. II: Results from 20 babies","volume":"71","author":"Ahluwalia","year":"1994","journal-title":"Archives of Disease in Childhood Fetal Neonatal Edition"},{"key":"10.1002\/14651858.CD004503.pub2-BIB0009|cit9","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1016\/S0022-3476(79)80372-8","article-title":"Variations in inspiratory:expiratory ratio and airway pressure wave form during mechanical ventilation: the significance of mean airway pressure","volume":"94","author":"Boros","year":"1979","journal-title":"Journal of Pediatrics"},{"key":"10.1002\/14651858.CD004503.pub2-BIB0010|cit10","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1542\/peds.74.4.487","article-title":"Using conventional infant ventilators at unconventional rates","volume":"74","author":"Boros","year":"1984","journal-title":"Pediatrics"},{"key":"10.1002\/14651858.CD004503.pub2-BIB0011|cit11","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1542\/peds.51.4.629","article-title":"Artificial ventilation in hyaline membrane disease: the use of positive end-expiratory pressure and continuous postive airway pressure","volume":"51","author":"Cumarasamy","year":"1973","journal-title":"Pediatrics"},{"key":"10.1002\/14651858.CD004503.pub2-BIB0012|cit12","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1136\/adc.40.213.474","article-title":"Intermittent positive pressure ventilation as a treatment in severe respiratory distress syndrome","volume":"40","author":"Delivoria-Papadopoulos","year":"1965","journal-title":"Arch Dis Child"},{"key":"10.1002\/14651858.CD004503.pub2-BIB0013|cit13","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1046\/j.1440-1754.1999.00349.x","article-title":"Changing mortality and causes of death in infants 23-27 weeks' gestational age","volume":"35","author":"Doyle","year":"1999","journal-title":"Journal of Paediatrics and Child Health"},{"key":"10.1002\/14651858.CD004503.pub2-BIB0014|cit14","volume-title":"Assisted Ventilation of the Newborn","author":"Goldsmith","year":"1996"},{"key":"10.1002\/14651858.CD004503.pub2-BIB0015|cit15","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/0378-3782(86)90007-1","article-title":"Fighting the ventilator - are fast rates an effective alternative to paralysis","volume":"13","author":"Greenough","year":"1986","journal-title":"Early Human Development"},{"key":"10.1002\/14651858.CD004503.pub2-BIB0016|cit16","doi-asserted-by":"crossref","first-page":"706","DOI":"10.1111\/j.1651-2227.1987.tb10553.x","article-title":"Comparison of different rates of artificial ventilation in preterm neonates with respiratory distress syndrome","volume":"76","author":"Greenough","year":"1987","journal-title":"Acta Paediatrica Scandinavica"},{"issue":"2","key":"10.1002\/14651858.CD004503.pub2-BIB0017|cit17","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD000456.pub2","article-title":"Synchronized mechanical ventilation for respiratory support in newborn infants","author":"Greenough","year":"2004","journal-title":"Cochrane Database of Systematic Reviews"},{"key":"10.1002\/14651858.CD004503.pub2-BIB0018|cit18","doi-asserted-by":"crossref","first-page":"1333","DOI":"10.1056\/NEJM197106172842401","article-title":"Treatment of the idiopathic respiratory distress syndrome with continuous positive airway pressure","volume":"284","author":"Gregory","year":"1971","journal-title":"New England Journal of Medicine"},{"key":"10.1002\/14651858.CD004503.pub2-BIB0019|cit19","volume-title":"Assisted ventilation of the newborn","author":"Harris","year":"1996"},{"key":"10.1002\/14651858.CD004503.pub2-BIB0020|cit20","doi-asserted-by":"crossref","first-page":"612","DOI":"10.1136\/adc.48.8.612","article-title":"Methods of improving oxygenation in infants mechanically ventilated for severe hyaline membrane disease","volume":"48","author":"Herman","year":"1973","journal-title":"Archives of Disease in Childhood"},{"key":"10.1002\/14651858.CD004503.pub2-BIB0021|cit21","doi-asserted-by":"crossref","first-page":"624","DOI":"10.1136\/adc.45.243.624","article-title":"Mechanical ventilation in the respiratory distress syndrome: a controlled trial","volume":"45","author":"Murdock","year":"1970","journal-title":"Archives of Disease in Childhood"},{"key":"10.1002\/14651858.CD004503.pub2-BIB0022|cit22","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1056\/NEJM196702162760701","article-title":"Pulmonary disease following respirator therapy of hyaline membrane disease. Bronchopulmonary dysplasia","volume":"276","author":"Northway","year":"1967","journal-title":"New England Journal of Medicine"},{"key":"10.1002\/14651858.CD004503.pub2-BIB0023|cit23","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1016\/S0022-3476(78)80282-0","article-title":"Incidence and evolution of subependymal and intraventricular hemorrhage: a study of infants with birthweights less than 1,500 gm","volume":"92","author":"Papile","year":"1978","journal-title":"Journal of Pediatrics"},{"key":"10.1002\/14651858.CD004503.pub2-BIB0024|cit24","doi-asserted-by":"crossref","first-page":"1247","DOI":"10.1136\/adc.62.12.1247","article-title":"Cerebral blood flow velocity variability in infants receiving assisted ventilation","volume":"62","author":"Rennie","year":"1987","journal-title":"Archives of Disease in Childhood"},{"key":"10.1002\/14651858.CD004503.pub2-BIB0025|cit25","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1136\/adc.46.246.152","article-title":"Effect of alterations in mechanical ventilator settings on pulmonary gas exchange in hyaline membrane disease","volume":"46","author":"Reynolds","year":"1971","journal-title":"Archives of Disease in Childhood"},{"key":"10.1002\/14651858.CD004503.pub2-BIB0026|cit26","first-page":"325","article-title":"Respiratory distress syndrome","volume-title":"Effective Care of the Newborn Infant","author":"Soll","year":"1992"},{"issue":"2","key":"10.1002\/14651858.CD004503.pub2-BIB0027|cit27","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD000144","article-title":"Natural surfactant versus synthetic surfactant for neonatal respiratory distress syndrome","author":"Soll","year":"2004","journal-title":"Cochrane Database of Systematic Reviews"},{"key":"10.1002\/14651858.CD004503.pub2-BIB0028|cit28","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1542\/peds.67.4.474","article-title":"Effects of alterations of inspiratory and expiratory pressures and inspiratory\/expiratory ratios on mean airway pressure, blood gases, and intracranial pressure","volume":"67","author":"Stewart","year":"1981","journal-title":"Pediatrics"},{"key":"10.1002\/14651858.CD004503.pub2-BIB0029|cit29","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1007\/BF02034755","article-title":"The effect of changes in inspiratory time on neonatal triggered ventilation","volume":"149","author":"Upton","year":"1990","journal-title":"European Journal of Pediatrics"},{"key":"10.1002\/14651858.CD004503.pub2-BIB0030|cit30","doi-asserted-by":"crossref","first-page":"966","DOI":"10.1542\/peds.32.6.966","article-title":"Reduction of mortality from respiratory distress syndrome of prematurity with early administration of intravenous glucose and sodium bicarbonate","volume":"32","author":"Usher","year":"1963","journal-title":"Pediatrics"},{"key":"10.1002\/14651858.CD004503.pub2-BIB0031|cit31","first-page":"57","article-title":"The infant lung. A case against high respiratory rates in controlled neonatal ventilation","volume":"3","author":"Weigl","year":"1973","journal-title":"Respiratory Therapy"},{"issue":"3","key":"10.1002\/14651858.CD004503.pub2-BIB0032|cit32","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD001456","article-title":"Early versus delayed selective surfactant treatment for neonatal respiratory distress syndrome","author":"Yost","year":"2003","journal-title":"Cochrane Database of Systematic Reviews"}],"container-title":["Cochrane Database of Systematic Reviews"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full\/10.1002\/14651858.CD004503.pub2","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,15]],"date-time":"2026-07-15T05:17:40Z","timestamp":1784092660000},"score":1,"resource":{"primary":{"URL":"http:\/\/doi.wiley.com\/10.1002\/14651858.CD004503.pub2"}},"subtitle":[],"editor":[{"name":"Cochrane Neonatal Group","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2003,10,20]]},"references-count":32,"aliases":["10.1002\/14651858.cd004503"],"journal-issue":{"issue":"1","published-online":{"date-parts":[[2010,1]]}},"URL":"https:\/\/doi.org\/10.1002\/14651858.cd004503.pub2","relation":{},"ISSN":["1465-1858"],"issn-type":[{"value":"1465-1858","type":"electronic"}],"subject":[],"published":{"date-parts":[[2003,10,20]]}}}