{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T20:49:45Z","timestamp":1790369385870,"version":"4.1.0"},"publisher-location":"Chichester, UK","reference-count":76,"publisher":"John Wiley & Sons, Ltd","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"DOI":"10.1002\/14651858.cd004760.pub2","type":"reference-entry","created":{"date-parts":[[2007,1,25]],"date-time":"2007-01-25T13:35:23Z","timestamp":1169732123000},"source":"Crossref","is-referenced-by-count":25,"title":["Creatine for treating muscle disorders"],"prefix":"10.1002","author":[{"given":"Rudolf A","family":"Kley","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthias","family":"Vorgerd","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark A","family":"Tarnopolsky","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2007,1,24]]},"reference":[{"issue":"1","key":"10.1002\/14651858.CD004760.pub2-BIB1|cit1","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1002\/ana.20523","article-title":"CINRG randomized controlled trial of creatine and glutamine in Duchenne muscular dystrophy","volume":"58","author":"Escolar","year":"2005","journal-title":"Annals of Neurology"},{"issue":"11","key":"10.1002\/14651858.CD004760.pub2-BIB2|cit2","doi-asserted-by":"crossref","first-page":"1748","DOI":"10.1212\/WNL.55.11.1748","article-title":"A placebo-controlled crossover trial of creatine in mitochondrial diseases","volume":"55","author":"Klopstock","year":"2000","journal-title":"Neurology"},{"issue":"4","key":"10.1002\/14651858.CD004760.pub2-BIB3|cit3","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1111\/j.1468-1331.2004.00970.x","article-title":"Creatine has no beneficial effect on skeletal muscle energy metabolism in patients with single mitochondrial DNA deletions: a placebo-controlled, double-blind 31P-MRS crossover study","volume":"12","author":"Kornblum","year":"2005","journal-title":"European Journal of Neurology"},{"issue":"5","key":"10.1002\/14651858.CD004760.pub2-BIB4|cit4","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1002\/mus.10355","article-title":"Beneficial effects of creatine supplementation in dystrophic patients","volume":"27","author":"Louis","year":"2003","journal-title":"Muscle & Nerve"},{"issue":"3","key":"10.1002\/14651858.CD004760.pub2-BIB5|cit5","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1212\/01.WNL.0000044405.29988.E1","article-title":"Creatine monohydrate in DM2\/PROMM: a double-blind placebo-controlled clinical study","volume":"60","author":"Schneider-Gold","year":"2003","journal-title":"Neurology"},{"issue":"12","key":"10.1002\/14651858.CD004760.pub2-BIB6|cit6","doi-asserted-by":"crossref","first-page":"1502","DOI":"10.1002\/(SICI)1097-4598(199712)20:12<1502::AID-MUS4>3.0.CO;2-C","article-title":"A randomized, controlled trial of creatine monohydrate in patients with mitochondrial cytopathies","volume":"20","author":"Tarnopolsky","year":"1997","journal-title":"Muscle & Nerve"},{"issue":"10","key":"10.1002\/14651858.CD004760.pub2-BIB7|cit7","doi-asserted-by":"crossref","first-page":"1771","DOI":"10.1212\/01.WNL.0000125178.18862.9D","article-title":"Creatine monohydrate enhances strength and body composition in Duchenne muscular dystrophy","volume":"62","author":"Tarnopolsky","year":"2004","journal-title":"Neurology"},{"issue":"1","key":"10.1002\/14651858.CD004760.pub2-BIB8|cit8","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1002\/mus.10527","article-title":"Creatine monohydrate supplementation does not increase muscle strength, lean body mass, or muscle phosphocreatine in patients with myotonic dystrophy type 1","volume":"29","author":"Tarnopolsky","year":"2004","journal-title":"Muscle & Nerve"},{"issue":"7","key":"10.1002\/14651858.CD004760.pub2-BIB9|cit9","doi-asserted-by":"crossref","first-page":"956","DOI":"10.1001\/archneur.57.7.956","article-title":"Creatine therapy in myophosphorylase deficiency (McArdle disease): a placebo-controlled crossover trial","volume":"57","author":"Vorgerd","year":"2000","journal-title":"Archives of Neurology"},{"issue":"1","key":"10.1002\/14651858.CD004760.pub2-BIB10|cit10","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1001\/archneur.59.1.97","article-title":"Effect of high-dose creatine therapy on symptoms of exercise intolerance in McArdle disease: double-blind, placebo-controlled crossover study","volume":"59","author":"Vorgerd","year":"2002","journal-title":"Archives of Neurology"},{"issue":"9","key":"10.1002\/14651858.CD004760.pub2-BIB11|cit11","doi-asserted-by":"crossref","first-page":"1848","DOI":"10.1212\/WNL.54.9.1848","article-title":"Creatine monohydrate in muscular dystrophies: A double-blind, placebo-controlled clinical study","volume":"54","author":"Walter","year":"2000","journal-title":"Neurology"},{"issue":"12","key":"10.1002\/14651858.CD004760.pub2-BIB12|cit12","doi-asserted-by":"crossref","first-page":"1717","DOI":"10.1007\/s00415-002-0923-x","article-title":"Creatine monohydrate in myotonic dystrophy: a double-blind, placebo-controlled clinical study","volume":"249","author":"Walter","year":"2002","journal-title":"Journal of Neurology"},{"issue":"3","key":"10.1002\/14651858.CD004760.pub2-BIB13|cit13","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1055\/s-2002-33679","article-title":"Effects of oral creatine supplementation in a patient with MELAS phenotype and associated nephropathy","volume":"33","author":"Barisic","year":"2002","journal-title":"Neuropediatrics"},{"issue":"2","key":"10.1002\/14651858.CD004760.pub2-BIB14|cit14","first-page":"276","article-title":"Trial therapy of acute polymyositis with phosphocreatine.","volume":"74","author":"Beurey","year":"1967","journal-title":"Bulletin de la Soci\u00e9t\u00e9 Fran\u00e7aise de Dermatologie et Syphiligraphie"},{"issue":"9","key":"10.1002\/14651858.CD004760.pub2-BIB15|cit15","doi-asserted-by":"crossref","first-page":"1299","DOI":"10.1002\/(SICI)1097-4598(199909)22:9<1299::AID-MUS24>3.0.CO;2-4","article-title":"Supplementation with creatine monohydrate in children with mitochondrial encephalomyopathies","volume":"22","author":"Borchert","year":"1999","journal-title":"Muscle & Nerve"},{"issue":"3","key":"10.1002\/14651858.CD004760.pub2-BIB16|cit16","first-page":"208","article-title":"Dermatomyositis with cardiac involvement and trial treatment with phosphocreatine","volume":"79","author":"Duperrat","year":"1972","journal-title":"Bulletin de la Soci\u00e9t\u00e9 Fran\u00e7aise de Dermatologie et Syphiligraphie"},{"issue":"2","key":"10.1002\/14651858.CD004760.pub2-BIB17|cit17","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1080\/01616412.2000.11741051","article-title":"Oral creatine supplementation in Duchenne muscular dystrophy: a clinical and 31P magnetic resonance spectroscopy study","volume":"22","author":"Felber","year":"2000","journal-title":"Neurological Research"},{"issue":"1 (8131)","key":"10.1002\/14651858.CD004760.pub2-BIB18|cit18","doi-asserted-by":"crossref","first-page":"1400","DOI":"10.1016\/S0140-6736(79)92031-2","article-title":"Phosphocreatinine in myotonic dystrophy (Steinert\u00b4s disease)","volume":"30","author":"Freddi","year":"1979","journal-title":"Lancet"},{"issue":"10","key":"10.1002\/14651858.CD004760.pub2-BIB19|cit19","first-page":"1236","article-title":"Creatine treatment in MELAS","volume":"17","author":"Hagenfeldt","year":"1994","journal-title":"Muscle & Nerve"},{"issue":"1","key":"10.1002\/14651858.CD004760.pub2-BIB20|cit20","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/S0887-8994(02)00469-1","article-title":"Effectiveness of creatine monohydrate in mitochondrial encephalomyopathies","volume":"28","author":"Komura","year":"2003","journal-title":"Pediatric Neurology"},{"issue":"10","key":"10.1002\/14651858.CD004760.pub2-BIB21|cit21","first-page":"661","article-title":"A clinical trial of creatine monohydrate in muscular dystrophy patients","volume":"44","author":"Matusmura","year":"2004","journal-title":"Rinsho Shinkeigaku"},{"key":"10.1002\/14651858.CD004760.pub2-BIB22|cit22","first-page":"375","article-title":"Lack of detectable effect of creatine supplementation on skeletal muscle or cardiac function in Duchenne muscular dystrophy","volume":"10","author":"Sejersen","year":"2000","journal-title":"Neuromuscular Disorders"},{"issue":"6","key":"10.1002\/14651858.CD004760.pub2-BIB23|cit23","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1097\/00005768-200106000-00003","article-title":"Effects of resistance exercise and creatine supplementation on myasthenia gravis: a case study","volume":"33","author":"Stout","year":"2001","journal-title":"Medicine and Science in Sports and Exercise"},{"issue":"4","key":"10.1002\/14651858.CD004760.pub2-BIB24|cit24","doi-asserted-by":"crossref","first-page":"854","DOI":"10.1212\/WNL.52.4.854","article-title":"Creatine monohydrate increases strength in patients with neuromuscular disease","volume":"52","author":"Tarnopolsky","year":"1999","journal-title":"Neurology"},{"issue":"3","key":"10.1002\/14651858.CD004760.pub2-BIB25|cit25","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1006\/nbdi.2001.0406","article-title":"Creatine increase survival and delays motor symptoms in a transgenic animal model of Huntington's disease","volume":"8","author":"Andreassen","year":"2001","journal-title":"Neurobiology of Disease"},{"issue":"1","key":"10.1002\/14651858.CD004760.pub2-BIB26|cit26","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1093\/gerona\/58.1.B11","article-title":"Creatine supplementation enhances isometric strength and body composition improvements following strength exercise training in older adults","volume":"58","author":"Brose","year":"2003","journal-title":"The journals of gerontology. Series A, Biological sciences and medical sciences."},{"issue":"11","key":"10.1002\/14651858.CD004760.pub2-BIB27|cit27","doi-asserted-by":"crossref","first-page":"1946","DOI":"10.1249\/01.MSS.0000093614.17517.79","article-title":"Effect of creatine and weight training on muscle creatine and performance in vegetarians","volume":"35","author":"Burke","year":"2003","journal-title":"Medicine and Science in Sports and Exercise"},{"issue":"1 Pt 1","key":"10.1002\/14651858.CD004760.pub2-BIB28|cit28","first-page":"E31","article-title":"Creatine ingestion favorably affects performance and muscle metabolism during maximal exercise in humans","volume":"271","author":"Casey","year":"1996","journal-title":"The American Journal of Physiology"},{"issue":"1","key":"10.1002\/14651858.CD004760.pub2-BIB29|cit29","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1002\/mus.20078","article-title":"Resistance training exercise and creatine in patients with Charcot-Marie-Tooth disease","volume":"30","author":"Chetlin","year":"2004","journal-title":"Muscle & Nerve"},{"key":"10.1002\/14651858.CD004760.pub2-BIB30|cit30","doi-asserted-by":"crossref","first-page":"1781","DOI":"10.1249\/01.MSS.0000142301.70419.C6","article-title":"Effect of creatine ingestion after exercise on muscle thickness in males and females","volume":"36","author":"Chilibeck","year":"2004","journal-title":"Medicine and Science in Sports and Exercise"},{"key":"10.1002\/14651858.CD004760.pub2-BIB31|cit31","first-page":"352","article-title":"Creatine monohydrate and resistance training increase bone mineral content and density in older men","volume":"9","author":"Chilibeck","year":"2005","journal-title":"The journal of Nutrition, Health & Aging"},{"issue":"12","key":"10.1002\/14651858.CD004760.pub2-BIB32|cit32","doi-asserted-by":"crossref","first-page":"2111","DOI":"10.1097\/00005768-200112000-00021","article-title":"Creatine supplementation combined with resistance training in older men","volume":"33","author":"Chrusch","year":"2001","journal-title":"Medicine and Science in Sports and Exercise"},{"issue":"3 Pt 2","key":"10.1002\/14651858.CD004760.pub2-BIB33|cit33","first-page":"R698","article-title":"Increase of total creatine in human brain after oral supplementation of creatine-monohydrate","volume":"277","author":"Dechent","year":"1999","journal-title":"American Journal of Physiology"},{"issue":"6","key":"10.1002\/14651858.CD004760.pub2-BIB34|cit34","doi-asserted-by":"crossref","first-page":"1359","DOI":"10.1046\/j.1471-4159.2003.01706.x","article-title":"Creatine therapy provides neuroprotection after onset of clinical symptoms in Huntington's disease transgenic mice","volume":"85","author":"Dedeoglu","year":"2003","journal-title":"Journal of Neurochemistry"},{"issue":"12","key":"10.1002\/14651858.CD004760.pub2-BIB35|cit35","doi-asserted-by":"crossref","first-page":"4389","DOI":"10.1523\/JNEUROSCI.20-12-04389.2000","article-title":"Neuroprotective effects of creatine in a transgenic mouse model of Huntington's disease","volume":"20","author":"Ferrante","year":"2000","journal-title":"Journal of Neuroscience"},{"issue":"1-2","key":"10.1002\/14651858.CD004760.pub2-BIB36|cit36","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1023\/A:1022413202549","article-title":"Creatine supplementation during college football training does not increase the incidence of cramping or injury","volume":"244","author":"Greenwood","year":"2003","journal-title":"Molecular and Cellular Biochemistry"},{"issue":"4","key":"10.1002\/14651858.CD004760.pub2-BIB37|cit37","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1002\/ana.10554","article-title":"A randomized sequential trial of creatine in amyotrophic lateral sclerosis","volume":"53","author":"Groeneveld","year":"2003","journal-title":"Annals of Neurology"},{"issue":"12","key":"10.1002\/14651858.CD004760.pub2-BIB38|cit38","doi-asserted-by":"crossref","first-page":"8418","DOI":"10.1016\/S0021-9258(18)52891-X","article-title":"Na(+)-dependent creatine transporter in rabbit brain, muscle, heart, and kidney. cDNA cloning and functional expression","volume":"268","author":"Guimbal","year":"1993","journal-title":"The Journal of Biological Chemistry"},{"issue":"26","key":"10.1002\/14651858.CD004760.pub2-BIB39|cit39","doi-asserted-by":"crossref","first-page":"17556","DOI":"10.1016\/S0021-9258(17)32477-8","article-title":"Cloning and sequencing of rat kidney L-arginine: glycine amidinotransferase. Studies on the mechanism of regulation by growth hormone and creatine","volume":"269","author":"Guthmiller","year":"1994","journal-title":"The Journal of Biological Chemistry"},{"issue":"3","key":"10.1002\/14651858.CD004760.pub2-BIB40|cit40","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1042\/cs0830367","article-title":"Elevation of creatine in resting and exercised muscle of normal subjects by creatine supplementation","volume":"83","author":"Harris","year":"1992","journal-title":"Clinical Science"},{"issue":"2","key":"10.1002\/14651858.CD004760.pub2-BIB41|cit41","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1212\/01.wnl.0000194318.74946.b6","article-title":"Creatine in Huntington disease is safe, tolerable, bioavailable in brain and reduces serum 8OH2'dG","volume":"66","author":"Hersch","year":"2006","journal-title":"Neurology"},{"issue":"1","key":"10.1002\/14651858.CD004760.pub2-BIB42|cit42","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1152\/jappl.1996.81.1.232","article-title":"Muscle creatine loading in men","volume":"81","author":"Hultman","year":"1996","journal-title":"Journal of Applied Physiology"},{"issue":"3","key":"10.1002\/14651858.CD004760.pub2-BIB43|cit43","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1038\/6568","article-title":"Neuroprotective effects of creatine in a transgenic animal model of amyotrophic lateral sclerosis","volume":"5","author":"Klivenyi","year":"1999","journal-title":"Nature Medicine"},{"issue":"3","key":"10.1002\/14651858.CD004760.pub2-BIB44|cit44","doi-asserted-by":"crossref","first-page":"610","DOI":"10.1016\/j.nbd.2003.12.014","article-title":"Neuroprotective mechanisms of creatine occur in the absence of mitochondrial creatine kinase","volume":"15","author":"Klivenyi","year":"2004","journal-title":"Neurobiology of Disease"},{"issue":"1-2","key":"10.1002\/14651858.CD004760.pub2-BIB45|cit45","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1023\/A:1022469320296","article-title":"Long-term creatine supplementation does not significantly affect clinical markers of health in athletes","volume":"244","author":"Kreider","year":"2003","journal-title":"Molecular and Cellular Biochemistry"},{"issue":"1-2","key":"10.1002\/14651858.CD004760.pub2-BIB46|cit46","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/S0006-8993(00)02038-2","article-title":"Neuroprotective effects of creatine administration against NMDA and malonate toxicity","volume":"860","author":"Malcon","year":"2000","journal-title":"Brain Research"},{"issue":"2","key":"10.1002\/14651858.CD004760.pub2-BIB47|cit47","doi-asserted-by":"crossref","DOI":"10.1002\/14651858.CD003725.pub2","article-title":"Glucocorticoid corticosteroids for Duchenne muscular dystrophy","author":"Manzur","year":"2004","journal-title":"Cochrane Database of Systematic Reviews"},{"issue":"6","key":"10.1002\/14651858.CD004760.pub2-BIB48|cit48","doi-asserted-by":"crossref","first-page":"839","DOI":"10.1002\/ana.410280620","article-title":"Phosphorus magnetic resonance spectroscopy of brain in mitochondrial cytopathies","volume":"28","author":"Matthews","year":"1990","journal-title":"Annals of Neurology"},{"issue":"1","key":"10.1002\/14651858.CD004760.pub2-BIB49|cit49","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1212\/WNL.41.1.114","article-title":"In vivo muscle magnetic resonance spectroscopy in the clinical investigation of mitochondrial disease","volume":"41","author":"Matthews","year":"1991","journal-title":"Neurology"},{"issue":"1","key":"10.1002\/14651858.CD004760.pub2-BIB50|cit50","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1523\/JNEUROSCI.18-01-00156.1998","article-title":"Neuroprotective effects of creatine and cyclocreatine in animal models of Huntington\u00b4s disease","volume":"18","author":"Matthews","year":"1998","journal-title":"Journal of Neuroscience"},{"issue":"1-2","key":"10.1002\/14651858.CD004760.pub2-BIB51|cit51","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/S0022-510X(01)00611-6","article-title":"Effects of creatine supplementation on exercise performance and muscular strength in amyotrophic lateral sclerosis: preliminary results","volume":"191","author":"Mazzini","year":"2001","journal-title":"Journal of the Neurological Sciences"},{"issue":"2","key":"10.1002\/14651858.CD004760.pub2-BIB52|cit52","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1097\/00005768-200002000-00007","article-title":"Acute creatine loading increases fat-free mass, but does not affect blood pressure, plasma creatinine, or CK activity in men and women","volume":"32","author":"Mihic","year":"2000","journal-title":"Medicine and Science in Sports and Exercise"},{"issue":"3","key":"10.1002\/14651858.CD004760.pub2-BIB53|cit53","doi-asserted-by":"crossref","first-page":"1041","DOI":"10.1152\/jappl.2001.91.3.1041","article-title":"Effects of acute creatine monohydrate supplementation on leucine kinetics and mixed-muscle protein synthesis","volume":"91","author":"Parise","year":"2001","journal-title":"Journal of Applied Physiology"},{"issue":"5","key":"10.1002\/14651858.CD004760.pub2-BIB54|cit54","doi-asserted-by":"crossref","first-page":"736","DOI":"10.1002\/art.1780370519","article-title":"Magnetic resonance imaging and P-31 magnetic resonance spectroscopy provide unique quantitative data useful in the longitudinal management of patients with dermatomyositis","volume":"37","author":"Park","year":"1994","journal-title":"Arthritis and Rheumatism"},{"issue":"1","key":"10.1002\/14651858.CD004760.pub2-BIB55|cit55","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1002\/art.1780380111","article-title":"Use of magnetic resonance imaging and P-31 magnetic resonance spectroscopy to detect and quantify muscle dysfunction in the amyopathic and myopathic variants of dermatomyositis","volume":"38","author":"Park","year":"1995","journal-title":"Arthritis and Rheumatism"},{"issue":"2","key":"10.1002\/14651858.CD004760.pub2-BIB56|cit56","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1016\/S0960-8966(01)00273-5","article-title":"Creatine supplementation reduces skeletal muscle degeneration and enhances mitochondrial function in mdx mice","volume":"12","author":"Passaquin","year":"2002","journal-title":"Neuromuscular Disorders"},{"issue":"1","key":"10.1002\/14651858.CD004760.pub2-BIB57|cit57","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1177\/0091270002239703","article-title":"Single- and multiple-dose pharmacokinetics of oral creatine","volume":"43","author":"Persky","year":"2003","journal-title":"Journal of Clinical Pharmacology"},{"issue":"8","key":"10.1002\/14651858.CD004760.pub2-BIB58|cit58","doi-asserted-by":"crossref","first-page":"1108","DOI":"10.1097\/00005768-199908000-00005","article-title":"Long-term oral creatine supplementation does not impair renal function in healthy athletes","volume":"31","author":"Poortmans","year":"1999","journal-title":"Medicine and Science in Sports and Exercise"},{"issue":"3","key":"10.1002\/14651858.CD004760.pub2-BIB59|cit59","doi-asserted-by":"crossref","first-page":"155","DOI":"10.2165\/00007256-200030030-00002","article-title":"Adverse effects of creatine supplementation: fact or fiction?","volume":"30","author":"Poortmans","year":"2000","journal-title":"Sports Medicine (Auckland, New Zealand)"},{"issue":"10","key":"10.1002\/14651858.CD004760.pub2-BIB60|cit60","doi-asserted-by":"crossref","first-page":"1717","DOI":"10.1249\/01.mss.0000176398.64189.e6","article-title":"Effect of oral creatine supplementation on urinary methylamine, formaldehyde, and formate","volume":"37","author":"Poortmans","year":"2005","journal-title":"Medicine and Science in Sports and Exercise"},{"issue":"3","key":"10.1002\/14651858.CD004760.pub2-BIB61|cit61","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1016\/S0014-5793(98)01399-4","article-title":"Creatine supplementation improves intracellular Ca2+ handling and survival in mdx skeletal muscle cells","volume":"439","author":"Pulido","year":"1998","journal-title":"FEBS Letters"},{"issue":"1","key":"10.1002\/14651858.CD004760.pub2-BIB62|cit62","first-page":"162","article-title":"Effects of repeated creatine supplementation on muscle, plasma, and urine creatine levels","volume":"18","author":"Rawson","year":"2004","journal-title":"Journal of Strength and Conditioning Research"},{"issue":"2","key":"10.1002\/14651858.CD004760.pub2-BIB63|cit63","doi-asserted-by":"crossref","DOI":"10.1002\/14651858.CD002276.pub2","article-title":"Drug treatment for facioscapulohumeral muscular dystrophy","author":"Rose","year":"2004","journal-title":"Cochrane Database of Systematic Reviews"},{"issue":"10","key":"10.1002\/14651858.CD004760.pub2-BIB64|cit64","doi-asserted-by":"crossref","first-page":"1008","DOI":"10.1139\/y02-129","article-title":"Dietary supplementation with creatine monohydrate prevents corticosteroid-induced attenuation of growth in young rats","volume":"80","author":"Roy","year":"2002","journal-title":"Canadian Journal of Physiology and Pharmacology"},{"issue":"3","key":"10.1002\/14651858.CD004760.pub2-BIB65|cit65","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1016\/j.yrtph.2006.05.005","article-title":"Risk assessment for creatine monohydrate","volume":"45","author":"Shao","year":"2006","journal-title":"Regulatory Toxicology and Pharmacology"},{"issue":"10","key":"10.1002\/14651858.CD004760.pub2-BIB66|cit66","doi-asserted-by":"crossref","first-page":"1656","DOI":"10.1212\/01.WNL.0000142992.81995.F0","article-title":"A clinical trial of creatine in ALS","volume":"63","author":"Shefner","year":"2004","journal-title":"Neurology"},{"issue":"5","key":"10.1002\/14651858.CD004760.pub2-BIB67|cit67","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1002\/1531-8249(200011)48:5<723::AID-ANA5>3.0.CO;2-W","article-title":"Dietary supplement creatine protects against traumatic brain injury","volume":"48","author":"Sullivan","year":"2000","journal-title":"Annals of Neurology"},{"issue":"9","key":"10.1002\/14651858.CD004760.pub2-BIB68|cit68","doi-asserted-by":"crossref","first-page":"1228","DOI":"10.1002\/(SICI)1097-4598(199909)22:9<1228::AID-MUS9>3.0.CO;2-6","article-title":"Direct measurement of high-energy phosphate compounds in patients with neuromuscular disease","volume":"22","author":"Tarnopolsky","year":"1999","journal-title":"Muscle & Nerve"},{"issue":"4","key":"10.1002\/14651858.CD004760.pub2-BIB69|cit69","doi-asserted-by":"crossref","first-page":"854","DOI":"10.1212\/WNL.52.4.854","article-title":"Creatine monohydrate increases strength in patients with neuromuscular disease","volume":"52","author":"Tarnopolsky","year":"1999","journal-title":"Neurology"},{"issue":"4","key":"10.1002\/14651858.CD004760.pub2-BIB70|cit70","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1123\/ijsnem.10.4.452","article-title":"Creatine monohydrate supplementation enhances high-intensity exercise performance in males and females","volume":"10","author":"Tarnopolsky","year":"2000","journal-title":"International Journal of Sport Nutrition and Exercise Metabolism"},{"issue":"5","key":"10.1002\/14651858.CD004760.pub2-BIB71|cit71","doi-asserted-by":"crossref","first-page":"682","DOI":"10.1002\/mus.1055","article-title":"Creatine transporter and mitochondrial creatine kinase protein content in myopathies","volume":"24","author":"Tarnopolsky","year":"2001","journal-title":"Muscle & Nerve"},{"issue":"3","key":"10.1002\/14651858.CD004760.pub2-BIB72|cit72","doi-asserted-by":"crossref","first-page":"706","DOI":"10.1097\/00005768-200003000-00024","article-title":"American College of Sports Medicine round table. The physiological and health effects of oral creatine supplementation","volume":"32","author":"Terjung","year":"2000","journal-title":"Medicine and Science in Sports and Exercise"},{"issue":"7","key":"10.1002\/14651858.CD004760.pub2-BIB73|cit73","doi-asserted-by":"crossref","first-page":"925","DOI":"10.1212\/01.WNL.0000090629.40891.4B","article-title":"Creatine supplementation in Huntington's disease: a placebo-controlled pilot trial","volume":"61","author":"Verbessem","year":"2003","journal-title":"Neurology"},{"issue":"2","key":"10.1002\/14651858.CD004760.pub2-BIB74|cit74","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/0005-2728(92)90096-K","article-title":"Mitochondrial creatine kinase: a key enzyme of aerobic energy metabolism","volume":"1102","author":"Wyss","year":"1992","journal-title":"Biochimica et biophysica acta"},{"issue":"4","key":"10.1002\/14651858.CD004760.pub2-BIB75|cit75","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1016\/S0306-9877(98)90058-5","article-title":"The therapeutic potential of oral creatine supplementation in muscle disease","volume":"51","author":"Wyss","year":"1998","journal-title":"Medical Hypotheses"},{"issue":"26","key":"10.1002\/14651858.CD004760.pub2-BIB76|cit76","doi-asserted-by":"crossref","first-page":"5909","DOI":"10.1523\/JNEUROSCI.1278-04.2004","article-title":"Prophylactic creatine administration mediates neuroprotection in cerebral ischemia in mice","volume":"24","author":"Zhu","year":"2004","journal-title":"The Journal of Neuroscience"}],"container-title":["Cochrane Database of Systematic Reviews"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cochranelibrary.com\/cdsr\/doi\/10.1002\/14651858.CD004760.pub2\/epdf\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,8,9]],"date-time":"2021-08-09T21:39:34Z","timestamp":1628545174000},"score":1,"resource":{"primary":{"URL":"https:\/\/doi.wiley.com\/10.1002\/14651858.CD004760.pub2"}},"subtitle":[],"editor":[{"given":"Rudolf A","family":"Kley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2007,1,24]]},"references-count":76,"URL":"https:\/\/doi.org\/10.1002\/14651858.cd004760.pub2","relation":{},"subject":[],"published":{"date-parts":[[2007,1,24]]}}}