{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T14:14:00Z","timestamp":1786976040090,"version":"build-2736575974"},"update-to":[{"DOI":"10.1002\/14651858.cd004834.pub2","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2020,8,27]],"date-time":"2020-08-27T00:00:00Z","timestamp":1598486400000}}],"reference-count":270,"publisher":"Wiley","issue":"8","content-domain":{"domain":["wiley.com","cochranelibrary.com"],"crossmark-restriction":true},"short-container-title":[],"DOI":"10.1002\/14651858.cd004834.pub3","type":"journal-article","created":{"date-parts":[[2020,8,27]],"date-time":"2020-08-27T13:42:41Z","timestamp":1598535761000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":27,"title":["Interventions for American cutaneous and mucocutaneous leishmaniasis"],"prefix":"10.1002","volume":"2020","author":[{"given":"Mariona","family":"Pinart","sequence":"additional","affiliation":[{"name":"Free time independent Cochrane reviewer; Berlin Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9-Ram\u00f3n","family":"Rueda","sequence":"additional","affiliation":[{"name":"Department of Preventive Medicine and Public Health; University of the Basque Country; Leioa Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gustavo AS","family":"Romero","sequence":"additional","affiliation":[{"name":"Center for Tropical Medicine; University of Brasilia; Brasilia Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos Eduardo","family":"Pinz\u00f3n-Fl\u00f3rez","sequence":"additional","affiliation":[{"name":"Research Centre for Insurance Medicine; Keralty; Bogot\u00e1 Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karime","family":"Osorio-Arango","sequence":"additional","affiliation":[{"name":"Direcci\u00f3n de Redes en Salud P\u00fablica; Instituto Nacional de Salud; Bogot\u00e1 Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana Nilce","family":"Silveira Maia-Elkhoury","sequence":"additional","affiliation":[{"name":"Communicable Diseases and Environmental Determinants of Health (CDE), Neglected, Tropical and Vector Borne Diseases (VT); Pan American Health Organization\/ World Health Organization (PAHO\/WHO); Rio de Janeiro Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ludovic","family":"Reveiz","sequence":"additional","affiliation":[{"name":"Evidence and Intelligence for Action in Health Department; Pan American Health Organization (PAHO); Washington DC USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vanessa M","family":"Elias","sequence":"additional","affiliation":[{"name":"Evidence and Intelligence for Action in Health Department; Pan American Health Organization (PAHO); Washington DC USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John A","family":"Tweed","sequence":"additional","affiliation":[{"name":"c\/o Cochrane Skin Group; The University of Nottingham; Nottingham UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,8,27]]},"reference":[{"issue":"5","key":"10.1002\/14651858.CD004834.pub3-BIB0001|cit1","doi-asserted-by":"crossref","first-page":"1735","DOI":"10.1086\/315082","article-title":"Randomized, double-blind study of stibogluconate plus human granulocyte macrophage colony stimulating factor versus stibogluconate alone in the treatment of cutaneous leishmaniasis","volume":"180","author":"Almeida","year":"1999","journal-title":"Journal of Infectious Diseases"},{"issue":"5 Suppl 1","key":"10.1002\/14651858.CD004834.pub3-BIB0002|cit2","first-page":"AB155","article-title":"The efficacy of pentamidine in comparison to pentavalent antimonial in American tegumentary leishmaniasis: an open label, randomized, controlled trial","volume":"74","author":"Alves","year":"2016","journal-title":"Journal of the American Academy of Dermatology"},{"issue":"135","key":"10.1002\/14651858.CD004834.pub3-BIB0003|cit3","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3823\/1734","article-title":"Avaliation the therapeutic efficacy of fluconazol","volume":"8","author":"Alves Nor\u00f5es","year":"2015","journal-title":"International Archives of Medicine"},{"key":"10.1002\/14651858.CD004834.pub3-BIB0004|cit4","volume-title":"Avalia\u00e7ao da efic\u00e1cia terap\u00eautica do fluconazol na leishmaniose tegumentar humana [Doctoral hesis]","author":"Lima da Silva","year":"2012"},{"issue":"2","key":"10.1002\/14651858.CD004834.pub3-BIB0005|cit5","doi-asserted-by":"crossref","first-page":"133","DOI":"10.4269\/ajtmh.2005.72.133","article-title":"Comparison of meglumine and pentamidine for Peruvian cutaneous leishmaniasis","volume":"72","author":"Andersen","year":"2005","journal-title":"American Journal of Tropical Medicine and Hygiene"},{"issue":"3","key":"10.1002\/14651858.CD004834.pub3-BIB0006|cit6","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1093\/clinids\/18.3.381","article-title":"Efficacy of a short course (10 days) of high-dose meglumine antimoniate with or without Interferon-gamma in treating cutaneous leishmaniasis in Guatemala","volume":"18","author":"Arana","year":"1994","journal-title":"Clinical Infectious Diseases"},{"issue":"5","key":"10.1002\/14651858.CD004834.pub3-BIB0007|cit7","doi-asserted-by":"crossref","first-page":"466","DOI":"10.4269\/ajtmh.2001.65.466","article-title":"Randomized, controlled, double-blind trial of topical treatment of cutaneous leishmaniasis with the paromomycin plus methylbenzethonium chloride ointment in Guatemala","volume":"65","author":"Arana","year":"2001","journal-title":"American Journal of Tropical Medicine and Hygiene"},{"issue":"12","key":"10.1002\/14651858.CD004834.pub3-BIB0008|cit8","doi-asserted-by":"crossref","first-page":"1549","DOI":"10.1086\/518172","article-title":"Role of imiquimod and parenteral meglumine antimoniate in the intitial treatment of cutaneous lesihmaniasis","volume":"44","author":"Ar\u00e9valo","year":"2007","journal-title":"Clinical Infectious Diseases"},{"issue":"2","key":"10.1002\/14651858.CD004834.pub3-BIB0009|cit9","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/j.actatropica.2004.03.009","article-title":"Comparison of the effectiveness of two topical paromomycin treatments versus meglumine antimoniate for New World cutaneous leishmaniasis","volume":"91","author":"Armijos","year":"2004","journal-title":"Acta Tropica"},{"issue":"8549","key":"10.1002\/14651858.CD004834.pub3-BIB0010|cit10","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/S0140-6736(87)93053-4","article-title":"Safety and efficacy of high-dose sodium stibogluconate therapy of American cutaneous leishmaniasis","volume":"4","author":"Ballou","year":"1987","journal-title":"Lancet"},{"issue":"4","key":"10.1002\/14651858.CD004834.pub3-BIB0011|cit11","doi-asserted-by":"crossref","first-page":"617","DOI":"10.4269\/ajtmh.12-0729","article-title":"Clinical and immunological outcome in cutaneous leishmaniasis patients treated with pentoxifylline","volume":"90","author":"Brito","year":"2014","journal-title":"American Journal of Tropical Medicine and Hygiene"},{"issue":"5","key":"10.1002\/14651858.CD004834.pub3-BIB0012|cit12","doi-asserted-by":"crossref","first-page":"1155","DOI":"10.4269\/ajtmh.16-0435","article-title":"Oral pentoxifylline associated with pentavalent antimony: a randomized trial for cutaneous leishmaniasis","volume":"96","author":"Brito","year":"2017","journal-title":"American Journal of Tropical Medicine and Hygiene"},{"issue":"3","key":"10.1002\/14651858.CD004834.pub3-BIB0013|cit13","doi-asserted-by":"publisher","first-page":"116","DOI":"10.7705\/biomedica.v15i3.868","article-title":"Evaluation of allopurinol-riboside therapy against Ecuadorian cutaneous leishmaniasis","volume":"15","author":"Chico","year":"1995","journal-title":"Biomedica"},{"issue":"2","key":"10.1002\/14651858.CD004834.pub3-BIB0014|cit14","doi-asserted-by":"crossref","first-page":"255","DOI":"10.4269\/ajtmh.2011.10-0155","article-title":"Randomized controlled clinical trial to access efficacy and safety of miltefosine in the treatment of cutaneous leishmaniasis caused by Leishmania (Viannia) guyanensis in Manaus, Brazil","volume":"84","author":"Chrusciak-Talhari","year":"2011","journal-title":"American Journal of Tropical Medicine and Hygiene"},{"issue":"8530","key":"10.1002\/14651858.CD004834.pub3-BIB0015|cit15","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1016\/S0140-6736(87)90116-4","article-title":"Immunotherapy versus chemotherapy in localised cutaneous leishmaniasis","volume":"21","author":"Convit","year":"1987","journal-title":"Lancet"},{"issue":"1","key":"10.1002\/14651858.CD004834.pub3-BIB0016|cit16","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1093\/infdis\/160.1.104","article-title":"Immunotherapy of localized, intermediate, and diffuse forms of American cutaneous leishmaniasis","volume":"160","author":"Convit","year":"1989","journal-title":"Journal of Infectious Diseases"},{"issue":"5","key":"10.1002\/14651858.CD004834.pub3-BIB0017|cit17","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1590\/S0037-86821996000500007","article-title":"Comparative study of meglumine antimoniate, pentamidine isothionate and aminosidine sulphate in the treatment of primary skin lesions caused by Leishmania (viannia) braziliensis","volume":"29","author":"Correia","year":"1996","journal-title":"Revista da Sociedade Brasilera de Medicina Tropical"},{"issue":"4 Suppl","key":"10.1002\/14651858.CD004834.pub3-BIB0018|cit18","first-page":"536","article-title":"Effect of the addition of pentoxifylline on the therapeutic and inflammatory response in patients with cutaneous leishmaniasis: a randomized placebo controlled trial","volume":"93","author":"Cossio-Duque","year":"2015","journal-title":"Frontiers"},{"issue":"12","key":"10.1002\/14651858.CD004834.pub3-BIB0019|cit19","doi-asserted-by":"crossref","first-page":"938","DOI":"10.1046\/j.1365-4362.1997.00308.x","article-title":"Evaluating the efficacy of allopurinol for treatment of cutaneous leishmaniasis","volume":"36","author":"Machado","year":"1997","journal-title":"International Journal of Dermatology"},{"issue":"6","key":"10.1002\/14651858.CD004834.pub3-BIB0020|cit20","doi-asserted-by":"crossref","first-page":"1108","DOI":"10.4269\/ajtmh.2006.75.1108","article-title":"Oral rehydration solution to prevent nephrotoxicity of amphotericin B","volume":"75","author":"Echevarria","year":"2006","journal-title":"American Journal of Tropical Medicine and Hygiene"},{"key":"10.1002\/14651858.CD004834.pub3-BIB0021|cit21","volume-title":"Compara\u00e7\u00e3o entre o esquema padr\u00e3o e alternativo de antimoniato de meglumina no tratamento da leishmaniose mucocut\u00e2nea ou mucosa [Comparison of the standard scheme and alternative meglumine antimoniate in the treatment of leishmaniasis mucocutaneous or muc","author":"Ferreira Terceiro","year":"2014"},{"issue":"2","key":"10.1002\/14651858.CD004834.pub3-BIB0022|cit22","first-page":"87","article-title":"Treatment of American cutaneous leishmaniasis by N-methyl-glucamine. Double-blind study with dosages of 14 mg\/kg\/day and 28 mg\/kg\/day of antimony","volume":"66","author":"Figueiredo Kopke","year":"1991","journal-title":"Anais Brasileiros de Dermatologia"},{"issue":"1","key":"10.1002\/14651858.CD004834.pub3-BIB0023|cit23","doi-asserted-by":"crossref","first-page":"77","DOI":"10.4269\/ajtmh.1994.51.77","article-title":"Efficacy of 28-day and 40-day regimens of sodium stibogluconate (pentostam) in the treatment of mucosal leishmaniasis","volume":"51","author":"Franke","year":"1994","journal-title":"American Journal of Tropical Medicine and Hygiene"},{"issue":"10","key":"10.1002\/14651858.CD004834.pub3-BIB0024|cit24","doi-asserted-by":"crossref","first-page":"e0006850","DOI":"10.1371\/journal.pntd.0006850","article-title":"An open label randomized clinical trial comparing the safety and effectiveness of one, two or three weekly pentamidine isethionate doses (seven milligrams per kilogram) in the treatment of cutaneous leishmaniasis in the Amazon Region","volume":"12","author":"Gadelha","year":"2018","journal-title":"PLOS Neglected Tropical Diseases"},{"issue":"5","key":"10.1002\/14651858.CD004834.pub3-BIB0025|cit25","first-page":"371","article-title":"Miltefosine versus meglumine antimoniate in the treatment of mucosal leishmaniasis","volume":"74","author":"Garcia Bustos","year":"2014","journal-title":"Medicina"},{"issue":"1","key":"10.1002\/14651858.CD004834.pub3-BIB0026|cit26","doi-asserted-by":"crossref","first-page":"92","DOI":"10.4269\/ajtmh.1991.45.92","article-title":"Placebo controlled treatment of Ecuadorian cutaneous leishmaniasis","volume":"45","author":"Guderian","year":"1991","journal-title":"American Journal of Tropical Medicine and Hygiene"},{"key":"10.1002\/14651858.CD004834.pub3-BIB0027|cit27","doi-asserted-by":"publisher","first-page":"23353","DOI":"10.3402\/fnr.v58.23353","article-title":"Nutritional status in patients with cutaneous leishmaniasis and a study of the effects of zinc supplementation together with antimony treatment","volume":"58","author":"Guzman-Rivero","year":"2014","journal-title":"Food & Nutrition Research"},{"issue":"6","key":"10.1002\/14651858.CD004834.pub3-BIB0028|cit28","doi-asserted-by":"crossref","first-page":"700","DOI":"10.1016\/0035-9203(94)90237-2","article-title":"Aminosidine (paromomycin) versus sodium stibogluconate for the treatment of American cutaneous leishmaniasis","volume":"88","author":"Hepburn","year":"1994","journal-title":"Transactions of the Royal Society of Tropical Medicine and Hygiene"},{"issue":"3","key":"10.1002\/14651858.CD004834.pub3-BIB0029|cit29","doi-asserted-by":"crossref","first-page":"e0003592","DOI":"10.1371\/journal.pntd.0003592","article-title":"Randomized single-blinded non-inferiority trial of 7 mg\/kg pentamidine isethionate versus 4 mg\/kg pentamidine isethionate for cutaneous leishmaniaisis in Suriname","volume":"9","author":"Hu","year":"2015","journal-title":"PLOS Neglected Tropical Diseases"},{"issue":"4","key":"10.1002\/14651858.CD004834.pub3-BIB0030|cit30","doi-asserted-by":"crossref","first-page":"640","DOI":"10.4269\/ajtmh.2007.77.640","article-title":"A randomized clinical trial comparing oral azithromycin and meglumine antimoniate for the treatment of American cutaneous leishmaniasis caused by Leishmania (Viannia) braziliensis","volume":"77","author":"Krolewiecki","year":"2007","journal-title":"American Journal of Tropical Medicine and Hygiene"},{"issue":"3","key":"10.1002\/14651858.CD004834.pub3-BIB0031|cit31","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1086\/513776","article-title":"Efficacy of sodium stibogluconate alone and in combination with allopurinol for treatment of mucocutaneous leishmaniasis","volume":"25","author":"Llanos-Cuentas","year":"1997","journal-title":"Clinical Infectious Diseases"},{"issue":"6","key":"10.1002\/14651858.CD004834.pub3-BIB0032|cit32","doi-asserted-by":"crossref","first-page":"1128","DOI":"10.4269\/ajtmh.2007.76.1128","article-title":"Parenteral aminosidine is not effective for peruvian mucocutaneous leishmaniasis","volume":"76","author":"Llanos-Cuentas","year":"2007","journal-title":"American Journal of Tropical Medicine and Hygiene"},{"issue":"7","key":"10.1002\/14651858.CD004834.pub3-BIB0033|cit33","doi-asserted-by":"crossref","first-page":"642","DOI":"10.1016\/j.trstmh.2005.08.011","article-title":"Heat therapy for cutaneous leishmaniasis elicits a systemic cytokine response similar to that of antimonial (Glucantime) therapy","volume":"100","author":"Lobo","year":"2006","journal-title":"Transactions of the Royal Society of Tropical Medicine and Hygiene"},{"issue":"7","key":"10.1002\/14651858.CD004834.pub3-BIB0034|cit34","doi-asserted-by":"crossref","first-page":"e0006653","DOI":"10.1371\/journal.pntd.0006653","article-title":"A phase II study to evaluate the safety and efficacy of topical 3% amphotericin B cream (Anfoleish) for the treatment of uncomplicated cutaneous leishmaniasis in Colombia","volume":"12","author":"L\u00f3pez","year":"2018","journal-title":"PLOS Neglected Tropical Disiseases"},{"issue":"1","key":"10.1002\/14651858.CD004834.pub3-BIB0035|cit35","doi-asserted-by":"crossref","first-page":"97","DOI":"10.4269\/ajtmh.2010.09-0287","article-title":"A controlled, randomized-blinded clinical trial to assess the efficacy of a nitric oxide releasing patch in the treatment of cutaneous leishmaniasis by Leishmania (V.) panamensis","volume":"83","author":"Lopez-Jaramillo","year":"2010","journal-title":"American Journal of Tropical Medicine and Hygiene"},{"issue":"6","key":"10.1002\/14651858.CD004834.pub3-BIB0036|cit36","doi-asserted-by":"crossref","first-page":"788","DOI":"10.1086\/511643","article-title":"Oral pentoxifylline combined with pentavalent antimony: a randomized trial for mucosal leishmaniasis","volume":"44","author":"Machado","year":"2007","journal-title":"Clinical Infectious Diseases"},{"issue":"12","key":"10.1002\/14651858.CD004834.pub3-BIB0037|cit37","doi-asserted-by":"publisher","first-page":"e912","DOI":"10.4269\/ajtmh.2009.81.201","article-title":"Efficacy of miltefosine in the treatment of American cutaneous leishmaniasis caused by leishmania braziliensis in Brazil","volume":"4","author":"Machado","year":"2010","journal-title":"PLOS Neglected Tropical Diseases"},{"issue":"9","key":"10.1002\/14651858.CD004834.pub3-BIB0038|cit38","doi-asserted-by":"crossref","first-page":"936","DOI":"10.1111\/tmi.13119","article-title":"Tamoxifen and meglumine antimoniate combined therapy in cutaneous leishmaniasis patients: a randomised trial","volume":"23","author":"Machado","year":"2018","journal-title":"Tropical Medicine & International Health"},{"issue":"2","key":"10.1002\/14651858.CD004834.pub3-BIB0039|cit39","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1046\/j.1365-4362.2002.01336.x","article-title":"Immunochemotherapy for cutaneous leishmaniasis: a controlled trial using killed Leishmania (Leishmania) amazonensis vaccine plus antimonial","volume":"41","author":"Machado-Pinto","year":"2002","journal-title":"International Journal of Dermatology"},{"issue":"11","key":"10.1002\/14651858.CD004834.pub3-BIB0040|cit40","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1056\/NEJM199203123261105","article-title":"Allopurinol in the treatment of American cutaneous leishmaniasis","volume":"326","author":"Mart\u00ednez","year":"1992","journal-title":"New England Journal of Medicine"},{"issue":"2","key":"10.1002\/14651858.CD004834.pub3-BIB0041|cit41","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1093\/clinids\/24.2.165","article-title":"Treatment of cutaneous leishmaniasis with allopurinol and stibogluconate","volume":"24","author":"Mart\u00ednez","year":"1997","journal-title":"Clinical Infectious Diseases"},{"issue":"10","key":"10.1002\/14651858.CD004834.pub3-BIB0042|cit42","doi-asserted-by":"crossref","first-page":"1395","DOI":"10.1086\/429238","article-title":"Randomized, double-blind clinical trial of topical imiquimod 5% with parenteral meglumine antimoniate in the treatment of cutaneous leishmaniasis in Peru","volume":"40","author":"Miranda-Ver\u00e1stegui","year":"2005","journal-title":"Clinical Infectious Diseases"},{"issue":"7","key":"10.1002\/14651858.CD004834.pub3-BIB0043|cit43","doi-asserted-by":"crossref","first-page":"e491","DOI":"10.1371\/journal.pntd.0000491","article-title":"First-line therapy for human cutaneous leishmaniasis in Peru using the TLR7 agonist imiquimod in combination with pentavalent antimony","volume":"3","author":"Miranda-Ver\u00e1stegui","year":"2009","journal-title":"PLOS Neglected Tropical Diseases"},{"issue":"1","key":"10.1002\/14651858.CD004834.pub3-BIB0044|cit44","doi-asserted-by":"crossref","first-page":"43","DOI":"10.4269\/ajtmh.1990.42.43","article-title":"Placebo-controlled clinical trial of meglumine antimoniate (glucantime) versus localized controlled heat in the treatment of cutaneous leishmaniasis in Guatemala","volume":"42","author":"Navin","year":"1990","journal-title":"American Journal of Tropical Medicine and Hygiene"},{"issue":"3","key":"10.1002\/14651858.CD004834.pub3-BIB0045|cit45","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1093\/infdis\/165.3.528","article-title":"Placebo-controlled clinical trial of sodium stibogluconate (pentostam) versus ketoconazole for treating cutaneous leishmaniasis in Guatemala","volume":"165","author":"Navin","year":"1992","journal-title":"Journal of Infectious Diseases"},{"key":"10.1002\/14651858.CD004834.pub3-BIB0046|cit46","unstructured":"A study of the efficacy and safety of the LEISH-F2 + MPL-SE vaccine for treatment of cutaneous leishmaniasis clinicaltrials.gov\/ct2\/show\/study\/NCT01011309"},{"issue":"4","key":"10.1002\/14651858.CD004834.pub3-BIB0047|cit47","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1016\/S0035-9203(97)90290-X","article-title":"Non-ulcerative cutaneous leishmaniasis in Honduras fails to respond to topical paromomycin","volume":"91","author":"Neva","year":"1997","journal-title":"Transactions of the Royal Society of Tropical Medicine and Hygiene"},{"issue":"6","key":"10.1002\/14651858.CD004834.pub3-BIB0048|cit48","doi-asserted-by":"crossref","first-page":"1092","DOI":"10.1590\/S0365-05962011000600005","article-title":"A randomized clinical trial comparing meglumine antimoniate, pentamidine and amphotericin B for the treatment of cutaneous leishmaniasis by Leishmania guyanensis","volume":"86","author":"Neves","year":"2011","journal-title":"Anais Brasileiros de Dermatologia"},{"issue":"4","key":"10.1002\/14651858.CD004834.pub3-BIB0049|cit49","doi-asserted-by":"crossref","first-page":"551","DOI":"10.4269\/ajtmh.2011.10-0423","article-title":"Antihelminthic therapy and antimony in cutaneous leishmaniasis: a randomized, double-blind, placebo-controlled trial in patients co-infected with helminths and Leishmania braziliensis","volume":"84","author":"Newlove","year":"2011","journal-title":"American Journal of Tropical Medicine and Hygiene"},{"issue":"6","key":"10.1002\/14651858.CD004834.pub3-BIB0050|cit50","first-page":"496","article-title":"Treatment of American cutaneous leishmaniasis: a comparison between low dosage (5mg\/kg\/day) and high dosage (20 mg\/kg\/day) antimony regimens","volume":"45","author":"Oliveira-Neto","year":"1997","journal-title":"Pathologie-biologie"},{"issue":"5","key":"10.1002\/14651858.CD004834.pub3-BIB0051|cit51","doi-asserted-by":"crossref","first-page":"856","DOI":"10.4269\/ajtmh.1985.34.856","article-title":"American cutaneous leishmaniasis: a comparison of three sodium stibogluconate treatment schedules","volume":"34","author":"Oster","year":"1985","journal-title":"American Journal of Tropical Medicine and Hygiene"},{"issue":"3-4","key":"10.1002\/14651858.CD004834.pub3-BIB0052|cit52","doi-asserted-by":"crossref","first-page":"187","DOI":"10.4269\/ajtmh.2001.64.187","article-title":"Treatment failure in children in a randomized clinical trial with 10 and 20 days of meglumine antimoniate for cutaneous leishmaniasis due to leishmania viannia species","volume":"64","author":"Palacios","year":"2001","journal-title":"American Journal of Tropical Medicine and Hygiene"},{"issue":"1","key":"10.1002\/14651858.CD004834.pub3-BIB0053|cit53","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1093\/cid\/ciw662","article-title":"Fluconazole in the treatment of cutaneous leishmaniasis caused by Leishmania braziliensis: a randomized controlled trial","volume":"64","author":"Prates","year":"2017","journal-title":"Clinical Infectious Diseases"},{"issue":"10","key":"10.1002\/14651858.CD004834.pub3-BIB0054|cit54","doi-asserted-by":"crossref","first-page":"4809","DOI":"10.1128\/AAC.00628-13","article-title":"Pharmacokinetics and absorption of paromomycin and gentamicin from topical creams used to treat cutaneous leishmaniasis","volume":"57","author":"Ravis","year":"2013","journal-title":"Antimicrobial Agents and Chemotherapy"},{"issue":"4","key":"10.1002\/14651858.CD004834.pub3-BIB0055|cit55","doi-asserted-by":"crossref","first-page":"684","DOI":"10.1093\/infdis\/jir816","article-title":"Noninferiority of miltefosine versus meglumine antimoniate for cutaneous leishmaniasis in children","volume":"205","author":"Rubiano","year":"2012","journal-title":"Journal of Infectious Diseases"},{"issue":"3","key":"10.1002\/14651858.CD004834.pub3-BIB0056|cit56","first-page":"148","article-title":"Evaluation of the effectiveness and toxicity of pentostam and glucantime in the treatment of cutaneous leishmaniasis","volume":"12","author":"Saenz","year":"1987","journal-title":"Revista M\u00e9dica de Panam\u00e1"},{"issue":"2","key":"10.1002\/14651858.CD004834.pub3-BIB0057|cit57","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/0002-9343(90)90292-L","article-title":"Efficacy of ketoconazole against leishmania braziliensis panamensis cutaneous leishmaniasis","volume":"89","author":"Saenz","year":"1990","journal-title":"American Journal of Medicine"},{"key":"10.1002\/14651858.CD004834.pub3-BIB0058|cit58","unstructured":"Lyra MR Phase III clinical trial for American cutaneous leishmaniasis. Equivalence between high and low dose schemes of meglumine antimoniate [Masters thesis] www.arca.fiocruz.br\/handle\/icict\/14378"},{"issue":"4","key":"10.1002\/14651858.CD004834.pub3-BIB0059|cit59","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1590\/S0036-46652014000400004","article-title":"Factors associated with adherence to different treatment schemes with meglumine antimoniate in a clinical trial for cutaneous leishmaniasis","volume":"56","author":"Ribeiro","year":"2014","journal-title":"Revista do Instituto de Medicina Tropical de Sao Paulo"},{"issue":"5","key":"10.1002\/14651858.CD004834.pub3-BIB0060|cit60","doi-asserted-by":"crossref","first-page":"e0178592","DOI":"10.1371\/journal.pone.0178592","article-title":"Low versus high dose of antimony for American cutaneous leishmaniasis: a randomized controlled blind non-inferiority trial in Rio de Janeiro, Brazil","volume":"12","author":"Saheki","year":"2017","journal-title":"PLOS One"},{"key":"10.1002\/14651858.CD004834.pub3-BIB0061|cit61","unstructured":"Saheki MN A randomized, controlled, single blind, non-inferiority trial of low dose versus high dose meglumine antimoniate for American cutaneous leishmaniasis in Rio de Janeiro, Brazil [Masters thesis] www.arca.fiocruz.br\/handle\/icict\/12458"},{"key":"10.1002\/14651858.CD004834.pub3-BIB0062|cit62","doi-asserted-by":"crossref","first-page":"e20180292","DOI":"10.1590\/0037-8682-0292-2018","article-title":"A randomized, open-label clinical trial comparing the long-term effects of miltefosine and meglumine antimoniate for mucosal leishmaniasis","volume":"52","author":"Sampaio","year":"2019","journal-title":"Revista da Sociedade Brasileira de Medicina Tropical"},{"issue":"10","key":"10.1002\/14651858.CD004834.pub3-BIB0063|cit63","doi-asserted-by":"crossref","first-page":"1793","DOI":"10.1086\/424848","article-title":"Antimony plus recombinant human granulocyte-macrophage colony-stimulating factor applied topically in low doses enhances healing of cutaneous leishmaniasis ulcers: a randomized, double-blind, placebo-controlled study","volume":"190","author":"Santos","year":"2004","journal-title":"Journal of Infectious Diseases"},{"issue":"3","key":"10.1002\/14651858.CD004834.pub3-BIB0064|cit64","doi-asserted-by":"crossref","first-page":"557","DOI":"10.4269\/ajtmh.12-0736","article-title":"Randomized, double-blinded, phase 2 trial of wr 279,396 (paromomycin and gentamicin) for cutaneous leishmaniasis in Panama","volume":"89","author":"Sosa","year":"2013","journal-title":"American Journal of Tropical Medicine and Hygiene"},{"key":"10.1002\/14651858.CD004834.pub3-BIB0065|cit65","unstructured":"Phase 3 study of Walter Reed (WR) 279,396 and paromomycin alone for the treatment of cutaneous leishmaniasis in Panama clinicaltrials.gov\/ct2\/show\/study\/NCT01790659"},{"issue":"5","key":"10.1002\/14651858.CD004834.pub3-BIB0066|cit66","doi-asserted-by":"crossref","first-page":"e0007253","DOI":"10.1371\/journal.pntd.0007253","article-title":"Topical paromomycin for New World cutaneous leishmaniasis","volume":"13","author":"Sosa","year":"2019","journal-title":"PLOS Neglected Tropical Diseases"},{"issue":"6","key":"10.1002\/14651858.CD004834.pub3-BIB0067|cit67","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1016\/0035-9203(94)90235-6","article-title":"Limited efficacy of injectable aminosidine as single-agent therapy for Colombian cutaneous leishmaniasis","volume":"88","author":"Soto","year":"1994","journal-title":"Transactions of the Royal Society of Tropical Medicine and Hygiene"},{"issue":"1","key":"10.1002\/14651858.CD004834.pub3-BIB0068|cit68","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1086\/516267","article-title":"Topical paromomycin\/methylbenzethonium chloride plus parenteral meglumine antimoniate as treatment for American cutaneous leishmaniasis: controlled study","volume":"26","author":"Soto","year":"1998","journal-title":"Clinical Infectious Diseases"},{"issue":"2","key":"10.1002\/14651858.CD004834.pub3-BIB0069|cit69","doi-asserted-by":"crossref","first-page":"147","DOI":"10.4269\/ajtmh.2002.66.147","article-title":"Treatment of cutaneous leishmaniasis with a topical antileishmanial drug (WR279396): phase 2 pilot study","volume":"66","author":"Soto","year":"2002","journal-title":"American Journal of Tropical Medicine and Hygiene"},{"issue":"5","key":"10.1002\/14651858.CD004834.pub3-BIB0070|cit70","doi-asserted-by":"crossref","first-page":"577","DOI":"10.4269\/ajtmh.2004.71.577","article-title":"Comparison of generic to branded pentavalent antimony for treatment of new world cutaneous leishmaniasis","volume":"71","author":"Soto","year":"2004","journal-title":"American Journal of Tropical Medicine and Hygiene"},{"issue":"9","key":"10.1002\/14651858.CD004834.pub3-BIB0071|cit71","doi-asserted-by":"crossref","first-page":"1266","DOI":"10.1086\/383321","article-title":"Miltefosine for new world cutaneous leishmaniasis","volume":"38","author":"Soto","year":"2004","journal-title":"Clinical Infectious Diseases"},{"issue":"2","key":"10.1002\/14651858.CD004834.pub3-BIB0072|cit72","doi-asserted-by":"crossref","first-page":"210","DOI":"10.4269\/ajtmh.2008.78.210","article-title":"Efficacy of miltefosine for Bolivian cutaneous leishmaniasis","volume":"78","author":"Soto","year":"2008","journal-title":"American Journal of Tropical Medicine and Hygiene"},{"issue":"9","key":"10.1002\/14651858.CD004834.pub3-BIB0073|cit73","doi-asserted-by":"crossref","first-page":"1255","DOI":"10.1093\/cid\/cit049","article-title":"Intralesional antimony for single lesions of Bolivian cutaneous leishmaniasis","volume":"56","author":"Soto","year":"2013","journal-title":"Clinical Infectious Diseases"},{"issue":"4","key":"10.1002\/14651858.CD004834.pub3-BIB0074|cit74","doi-asserted-by":"crossref","first-page":"852","DOI":"10.4269\/ajtmh.15-0640","article-title":"Intralesional pentamidine: a novel therapy for single lesions of Bolivian cutaneous leishmaniasis","volume":"94","author":"Soto","year":"2016","journal-title":"American Journal of Tropical Medicine and Hygiene"},{"issue":"4","key":"10.1002\/14651858.CD004834.pub3-BIB0075|cit75","doi-asserted-by":"crossref","first-page":"852","DOI":"10.4269\/ajtmh.15-0640","article-title":"Intralesional pentamidine: a novel therapy for single lesions of Bolivian cutaneous leishmaniasis","volume":"94","author":"Soto","year":"2016","journal-title":"American Journal of Tropical Medicine and Hygiene"},{"issue":"5","key":"10.1002\/14651858.CD004834.pub3-BIB0076|cit76","doi-asserted-by":"crossref","first-page":"844","DOI":"10.1093\/cid\/ciy619","article-title":"Topical 15% paromomycin-aquaphilic for Bolivian leishmania braziliensis cutaneous leishmaniasis: a randomized, placebo-controlled trial","volume":"68","author":"Soto","year":"2019","journal-title":"Clinical Infectious Diseases"},{"issue":"Suppl 2","key":"10.1002\/14651858.CD004834.pub3-BIB0077|cit77","doi-asserted-by":"crossref","first-page":"S153","DOI":"10.1016\/S0926-9959(98)95122-4","article-title":"American cutaneous leishmaniasis: therapeutic study of pentamidine isotionate versus N-metil-glucantime","volume":"11","author":"Souza e Souza","year":"1998","journal-title":"Journal of the European Academy of Dermatology and Venereology : JEADV"},{"issue":"6","key":"10.1002\/14651858.CD004834.pub3-BIB0078|cit78","doi-asserted-by":"crossref","first-page":"756","DOI":"10.1590\/0037-8682-0266-2014","article-title":"Poor response to azithromycin in cutaneous leishmaniasis leading to a premature interruption of a multicentric phase III clinical trial in Brazil","volume":"47","author":"Toledo Junior","year":"2014","journal-title":"Revista Da Sociedade Brasileira de Medicina Tropical"},{"issue":"3","key":"10.1002\/14651858.CD004834.pub3-BIB0079|cit79","doi-asserted-by":"crossref","first-page":"232","DOI":"10.7326\/0003-4819-126-3-199702010-00010","article-title":"Inefficacy of allopurinol as monotherapy for Colombian cutaneous leishmaniasis: a randomized, controlled trial","volume":"126","author":"V\u00e9lez","year":"1997","journal-title":"Annals of Internal Medicine"},{"issue":"3","key":"10.1002\/14651858.CD004834.pub3-BIB0080|cit80","doi-asserted-by":"crossref","first-page":"S0036","DOI":"10.1590\/S0036-46652013000300011","article-title":"Thermotherapy effective and safer than miltefosine in the treatment of cutaneous leishmaniasis in Colombia","volume":"55","author":"L\u00f3pez","year":"2013","journal-title":"Revista do Instituto de Medicina Tropical de Sao Paulo"},{"key":"10.1002\/14651858.CD004834.pub3-BIB0081|cit81","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1186\/1745-6215-13-58","article-title":"Thermotherapy. An alternative for the treatment of American cutaneous leishmaniasis","volume":"13","author":"L\u00f3pez","year":"2012","journal-title":"Trials"},{"issue":"2","key":"10.1002\/14651858.CD004834.pub3-BIB0082|cit82","doi-asserted-by":"crossref","first-page":"351","DOI":"10.4269\/ajtmh.2010.10-0060","article-title":"Efficacy of miltefosine for the treatment of American cutaneous leishmaniasis","volume":"83","author":"V\u00e9lez","year":"2010","journal-title":"American Journal of Tropical Medicine and Hygiene"},{"issue":"9-10","key":"10.1002\/14651858.CD004834.pub3-BIB0083|cit83","doi-asserted-by":"crossref","first-page":"1320","DOI":"10.1016\/j.vaccine.2003.06.002","article-title":"Safety, immunogeneicity, and efficacy of an autoclaved leishmania amazonensis vaccine plus BCG adjuvant against New World cutaneous leishmaniasis","volume":"22","author":"Armijos","year":"2004","journal-title":"Vaccine"},{"issue":"9-10","key":"10.1002\/14651858.CD004834.pub3-BIB0084|cit84","doi-asserted-by":"crossref","first-page":"1179","DOI":"10.1016\/S0264-410X(98)00338-7","article-title":"Evaluation of the stability and immunogenicity of autoclaved and nonautoclaved preparations of a vaccine against American tegumentary leishmaniasis","volume":"17","author":"De Luca","year":"1999","journal-title":"Vaccine"},{"issue":"3","key":"10.1002\/14651858.CD004834.pub3-BIB0085|cit85","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1016\/S0001-706X(01)00181-4","article-title":"A randomized double-blind placebo-controlled trial to evaluate the immunogenicity of a candidate vaccine against American tegumentary leishmaniasis","volume":"80","author":"De Luca","year":"2001","journal-title":"Acta Tropica"},{"issue":"6","key":"10.1002\/14651858.CD004834.pub3-BIB0086|cit86","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1016\/S0035-9203(03)80109-8","article-title":"Randomized, double-blind, placebo-controlled study on the immunogenicity of the leishmanin skin test","volume":"97","author":"De Luca","year":"2003","journal-title":"Transactions of the Royal Society of Tropical Medicine and Hygiene"},{"issue":"6","key":"10.1002\/14651858.CD004834.pub3-BIB0087|cit87","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1590\/S0037-86822000000600004","article-title":"Evaluation of the efficacy and toxicity of N-methyl-glucamine vs BP88 Sodium Stibogluconate in the treatment of localized cutaneous leishmaniasis","volume":"33","author":"Deps","year":"2000","journal-title":"Revista da Sociedade Brasileira de Medicina Tropical"},{"issue":"1","key":"10.1002\/14651858.CD004834.pub3-BIB0088|cit88","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.actatropica.2006.11.007","article-title":"Skin reactivity to thimerosal and phenol-preserved Montenegro antigen in Brazil","volume":"101","author":"Fagundes","year":"2007","journal-title":"Acta Tropica"},{"key":"10.1002\/14651858.CD004834.pub3-BIB0089|cit89","first-page":"1241","volume-title":"Tratado de infectologia","author":"Falquete","year":"2002"},{"issue":"6","key":"10.1002\/14651858.CD004834.pub3-BIB0090|cit90","doi-asserted-by":"crossref","first-page":"893","DOI":"10.1067\/mjd.2003.218","article-title":"Treatment of cutaneous leishmaniasis by photodynamic therapy","volume":"48","author":"Gardlo","year":"2003","journal-title":"Journal of the American Academy of Dermatology"},{"issue":"6","key":"10.1002\/14651858.CD004834.pub3-BIB0091|cit91","doi-asserted-by":"crossref","first-page":"889","DOI":"10.4269\/ajtmh.1998.59.889","article-title":"Lack of efficacy of mefloquine in the treatment of New World cutaneous leishmaniasis in Colombia","volume":"59","author":"Hendrickx","year":"1998","journal-title":"American Journal of Tropical Medicine and Hygiene"},{"issue":"1","key":"10.1002\/14651858.CD004834.pub3-BIB0092|cit92","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1111\/j.1365-2133.1993.tb00149.x","article-title":"Cutaneous leishmaniasis in British troops from Belize","volume":"128","author":"Hepburn","year":"1993","journal-title":"British Journal of Dermatology"},{"issue":"4","key":"10.1002\/14651858.CD004834.pub3-BIB0093|cit93","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1016\/0035-9203(94)90432-4","article-title":"Hepatotoxicity of sodium stibogluconate therapy for American cutaneous leishmaniasis","volume":"88","author":"Hepburn","year":"1994","journal-title":"Transactions of the Royal Society of Tropical Medicine and Hygiene"},{"issue":"3","key":"10.1002\/14651858.CD004834.pub3-BIB0094|cit94","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1093\/infdis\/165.3.518","article-title":"The natural history of cutaneous leishmaniasis in Guatemala","volume":"165","author":"Herwaldt","year":"1992","journal-title":"Journal of Infectious Diseases"},{"issue":"2","key":"10.1002\/14651858.CD004834.pub3-BIB0095|cit95","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1086\/520249","article-title":"Topical paromomycin\/methylbenzethonium chloride plus parenteral meglumine antimonate as treatment of American cutaneous leishmaniasis: controlled study","volume":"29","author":"Krause","year":"1999","journal-title":"Clinical Infectious Diseases"},{"issue":"5","key":"10.1002\/14651858.CD004834.pub3-BIB0096|cit96","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1590\/S0037-86821999000500010","article-title":"Efficacy of mefloquine in the treatment of skin leishmaniasis in an endemic area of leishmania (viannia) braziliensis","volume":"32","author":"Laguna-Torres","year":"1999","journal-title":"Revista da Sociedade Brasileira de Medicina Tropical"},{"issue":"2","key":"10.1002\/14651858.CD004834.pub3-BIB0097|cit97","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1038\/ki.1991.214","article-title":"Effect of salt supplementation on amphotericin B nephrotoxicity","volume":"40","author":"Llanos","year":"1991","journal-title":"Kidney International"},{"issue":"46","key":"10.1002\/14651858.CD004834.pub3-BIB0098|cit98","doi-asserted-by":"crossref","first-page":"7427","DOI":"10.1016\/j.vaccine.2010.08.092","article-title":"A clinical trial to evaluate the safety and immunogenicity of the LEISH-F1+MPL-SE vaccine when used in combination with sodium stibogluconate for the treatment of mucosal leishmaniasis","volume":"28","author":"Llanos-Cuentas","year":"2010","journal-title":"Vaccine"},{"issue":"3","key":"10.1002\/14651858.CD004834.pub3-BIB0099|cit99","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1590\/S0074-02761994000300034","article-title":"Exploitation of parasite derived antigen in therapeutic success of human cutaneous leishmaniasis in Brazil","volume":"89","author":"Monjour","year":"1994","journal-title":"Mem\u00f3rias do Instituto Oswaldo Cruz"},{"issue":"3","key":"10.1002\/14651858.CD004834.pub3-BIB0100|cit100","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1111\/j.1468-3083.2011.04070.x","article-title":"A pilot study comparing low-dose liposomal amphotericin B with N-methyl glucamine for the treatment of American cutaneous leishmaniasis","volume":"26","author":"Motta","year":"2012","journal-title":"Journal of the European Academy of Dermatology and Venereology : JEADV"},{"issue":"7","key":"10.1002\/14651858.CD004834.pub3-BIB0101|cit101","doi-asserted-by":"crossref","first-page":"2198","DOI":"10.1128\/iai.58.7.2198-2203.1990","article-title":"Vaccination of humans against cutaneous leishmaniasis: cellular and humoral inmune responses","volume":"58","author":"Nascimento","year":"1990","journal-title":"Infection and Immunity"},{"issue":"6","key":"10.1002\/14651858.CD004834.pub3-BIB0102|cit102","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1590\/S0036-46652000000600004","article-title":"Mucosal leishmaniasis (\"espundia\") responsive to low dose of N-methyl glucantime in Rio de Janeiro, Brazil","volume":"42","author":"Oliveira-Neto","year":"2000","journal-title":"Revista do Instituto de Medicina Tropical de S\u00e3o Paulo"},{"issue":"4","key":"10.1002\/14651858.CD004834.pub3-BIB0103|cit103","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1590\/S0074-02761995000400020","article-title":"A randomized trial of amphotericin B alone or in combination with itraconazole in the treatment of mucocutaneous leishmaniasis","volume":"90","author":"Rodriguez","year":"1995","journal-title":"Mem\u00f3rias do Instituto Oswaldo Cruz"},{"issue":"4","key":"10.1002\/14651858.CD004834.pub3-BIB0104|cit104","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1590\/S0037-86822000000400009","article-title":"Comparative study between sodium stibogluconate BP 88 and meglumine antimoniate in cutaneous leishmaniasis treatment. II. Biochemical and cardiac toxicity","volume":"33","author":"Saldanha","year":"2000","journal-title":"Revista da Sociedade Brasileira de Medicina Tropical"},{"issue":"1","key":"10.1002\/14651858.CD004834.pub3-BIB0105|cit105","doi-asserted-by":"crossref","first-page":"107","DOI":"10.4269\/ajtmh.1994.50.107","article-title":"Successful treatment of Colombian cutaneous leishmaniasis with four injections of pentamidine","volume":"50","author":"Soto","year":"1994","journal-title":"American Journal of Tropical Medicine and Hygiene"},{"issue":"1","key":"10.1002\/14651858.CD004834.pub3-BIB0106|cit106","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1093\/clinids\/20.1.47","article-title":"Successful treatment of New World cutaneous leishmaniasis with a combination of topical paromomycin\/methylbenzethonium chloride and injectable meglumine antimonate","volume":"20","author":"Soto","year":"1995","journal-title":"Clinical Infectious Diseases"},{"issue":"3","key":"10.1002\/14651858.CD004834.pub3-BIB0107|cit107","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1093\/clind\/16.3.417","article-title":"Evaluation of pentamidine for the treatment of cutaneous leishmaniasis in Colombia","volume":"16","author":"Soto-Mancipe","year":"1993","journal-title":"Clinical Infectious Diseases"},{"issue":"7","key":"10.1002\/14651858.CD004834.pub3-BIB0108|cit108","doi-asserted-by":"crossref","first-page":"414","DOI":"10.1111\/j.1365-4362.1982.tb03163.x","article-title":"Oral ketoconazole in the treatment of leishmaniasis","volume":"21","author":"Urcuyo","year":"1982","journal-title":"International Journal of Dermatology"},{"issue":"6","key":"10.1002\/14651858.CD004834.pub3-BIB0109|cit109","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1590\/S0036-46651985000600002","article-title":"[Renal function in patients with mucocutaneous leishmaniasis treated with pentavalent antimony compounds]","volume":"27","author":"Veiga","year":"1985","journal-title":"Revista do Instituto de Medicina Tropical de Sao Paulo"},{"issue":"8","key":"10.1002\/14651858.CD004834.pub3-BIB0110|cit110","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1016\/j.trstmh.2005.04.002","article-title":"Failure of a killed Leishmania amazonensis vaccine against American cutaneous leishmaniasis in Colombia","volume":"99","author":"V\u00e9lez","year":"2005","journal-title":"Transactions of the Royal Society of Tropical Medicine and Hygiene"},{"issue":"3","key":"10.1002\/14651858.CD004834.pub3-BIB0111|cit111","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1086\/341406","article-title":"A randomized, double-blind study of the efficacy of a 10- or 20-day course of sodium stibogluconate for treatment of cutaneous leishmaniasis in United States military personnel","volume":"35","author":"Wortmann","year":"2002","journal-title":"Clinical Infectious Diseases"},{"key":"10.1002\/14651858.CD004834.pub3-BIB0112|cit112","unstructured":"Allopurinol, glucantime, or allopurinol\/glucantime for cutaneous leishmaniasis in Brazil clinicaltrials.gov\/ct2\/show\/record\/NCT00004755"},{"key":"10.1002\/14651858.CD004834.pub3-BIB0113|cit113","unstructured":"Study to evaluate the Leish-111F + MPL-SE vaccine in the treatment of mucosal leishmaniasis clinicaltrials.gov\/ct2\/show\/study\/NCT00111514"},{"key":"10.1002\/14651858.CD004834.pub3-BIB0114|cit114","unstructured":"Study to evaluate the Leish-111F + MPL-SE vaccine in the treatment of cutaneous leishmaniasis clinicaltrials.gov\/ct2\/show\/study\/NCT00111553"},{"key":"10.1002\/14651858.CD004834.pub3-BIB0115|cit115","unstructured":"Safety and efficacy of low-dose pentavalent antimony for treatment of cutaneous leishmaniasis (Lowdosesb) clinicaltrials.gov\/ct2\/show\/study\/NCT00317980"},{"key":"10.1002\/14651858.CD004834.pub3-BIB0116|cit116","unstructured":"Reduced doses of antimony plus ranulocyte monocyte colony stimulating factor (GM-CSF) for cutaneous leishmaniasis (GMCSFSbv) clinicaltrials.gov\/ct2\/show\/study\/NCT0973128"},{"key":"10.1002\/14651858.CD004834.pub3-BIB0117|cit117","unstructured":"Treatment of cutaneous leishmaniasis with a combination of miltefosine and antimony clinicaltrials.gov\/ct2\/show\/study\/NCT01380301"},{"key":"10.1002\/14651858.CD004834.pub3-BIB0118|cit118","unstructured":"Oral miltefosine plus topical imiquimod to treat cutaneous leishmaniasis clinicaltrials.gov\/ct2\/show\/record\/NCT01380314"},{"key":"10.1002\/14651858.CD004834.pub3-BIB0119|cit119","unstructured":"Add-on study of pentoxifylline in cutaneous leishmaniasis (GT) clinicaltrials.gov\/ct2\/show\/record\/NCT01464242"},{"key":"10.1002\/14651858.CD004834.pub3-BIB0120|cit120","unstructured":"Fourth-generation immucillin derivative DI4G associated therapy in cutaneous leishmaniasis clinicaltrials.gov\/ct2\/show\/study\/NCT03294161"},{"key":"10.1002\/14651858.CD004834.pub3-BIB0121|cit121","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1186\/1745-6215-7-14","article-title":"Double blind, randomized controlled trial, to evaluate the effectiveness of a controlled nitric oxide releasing patch versus meglumine antimoniate in the treatment of cutaneous leishmaniasis [NCT00317629]","volume":"7","author":"Silva","year":"2006","journal-title":"Trials"},{"key":"10.1002\/14651858.CD004834.pub3-BIB0122|cit122","unstructured":"Short course of miltefosine and antimony to treat cutaneous leishmaniasis in Bolivia clinicaltrials.gov\/ct2\/show\/study\/NCT00537953"},{"key":"10.1002\/14651858.CD004834.pub3-BIB0123|cit123","unstructured":"Low antimonial dosage in American mucosal leishmaniasis clinicaltrials.gov\/ct2\/show\/study\/NCT01301937"},{"key":"10.1002\/14651858.CD004834.pub3-BIB0124|cit124","unstructured":"The association of miltefosine and pentoxifylline to treat mucosal leishmaniasis: a clinical trial in Brazil clinicaltrials.gov\/ct2\/show\/study\/NCT02530697"},{"key":"10.1002\/14651858.CD004834.pub3-BIB0125|cit125","unstructured":"Thermotherapy + a short course of miltefosine for the treatment of uncomplicated cutaneous leishmaniasis in the New World clinicaltrials.gov\/ct2\/show\/study\/NCT02687971"},{"key":"10.1002\/14651858.CD004834.pub3-BIB0126|cit126","unstructured":"Miltefosine and GM-CSF in cutaneous leishmaniasis: a randomized and controlled trial clinicaltrials.gov\/ct2\/show\/NCT03023111"},{"key":"10.1002\/14651858.CD004834.pub3-BIB0127|cit127","unstructured":"Phase 2 trial to evaluate 18-methoxycoronaridine efficacy, safety and tolerability in cutaneous leishmaniasis patients clinicaltrials.gov\/ct2\/show\/study\/NCT03084952"},{"key":"10.1002\/14651858.CD004834.pub3-BIB0128|cit128","unstructured":"Oral miltefosine plus topical paromomycin In American cutaneous leishmaniasis clinicaltrials.gov\/show\/nct03829917"},{"key":"10.1002\/14651858.CD004834.pub3-BIB0129|cit129","unstructured":"Evaluation of the safety and clinical activity of Curaleish lotion and cream in the topical treatment of cutaneous leishmaniasis in Colombia clinicaltrials.gov\/ct2\/show\/NCT04072874"},{"key":"10.1002\/14651858.CD004834.pub3-BIB0130|cit130","unstructured":"Treatment of cutaneous leishmaniasis with pentamidine isethionate in Suriname; a comparison study between two treatment regimes, 3 days vs 7 days www.trialregister.nl\/trialreg\/admin\/rctview.asp?TC=2076"},{"key":"10.1002\/14651858.CD004834.pub3-BIB0131|cit131","unstructured":"A randomized, open label multicenter study to determine the efficacy and safety of combining thermotherapy and a short course of miltefosine for the treatment of uncomplicated cutaneous leishmaniasis in the New World www.ins.gob.pe\/ensayosclinicos\/rpec\/recuperarECPBNuevo.asp?ver=EN&numEc=007-16"},{"key":"10.1002\/14651858.CD004834.pub3-BIB0132|cit132","unstructured":"Comparison of the effect and toxicity between two options for the treatment of Mucosal Leishmaniasis: miltefosin and Liposomal Anfotericin B apps.who.int\/trialsearch\/Trial2.aspx?TrialID=RBR-5r93wn"},{"key":"10.1002\/14651858.CD004834.pub3-BIB0133|cit133","unstructured":"Multicentre study evaluating the efficacy and safety of Intralesional administration of Meglumine Antimoniate compared to systemic treatment for cutaneous leishmaniasis www.ensaiosclinicos.gov.br\/rg\/RBR-6mk5n4\/"},{"key":"10.1002\/14651858.CD004834.pub3-BIB0134|cit134","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1016\/j.meegid.2014.07.028","article-title":"What's behind a sand fly bite? The profound effect of sand fly saliva on host hemostasis, inflammation and immunity","volume":"28","author":"Abdeladhim","year":"2014","journal-title":"Infection, Genetics and Evolution"},{"issue":"1","key":"10.1002\/14651858.CD004834.pub3-BIB0135|cit135","doi-asserted-by":"crossref","first-page":"79","DOI":"10.4269\/ajtmh.1997.57.79","article-title":"Risk factors for onset of cutaneous and mucocutaneous leishmaniasis in Bolivia","volume":"57","author":"Alcais","year":"1997","journal-title":"American Journal of Tropical Medicine and Hygiene"},{"issue":"12","key":"10.1002\/14651858.CD004834.pub3-BIB0136|cit136","doi-asserted-by":"crossref","first-page":"1263","DOI":"10.1016\/j.trstmh.2009.04.018","article-title":"Relationship between coffee cultivation practices in Colombia and exposure to infection with Leishmania","volume":"103","author":"Alexander","year":"2009","journal-title":"Transactions of the Royal Society of Tropical Medicine and Hygiene"},{"issue":"1","key":"10.1002\/14651858.CD004834.pub3-BIB0137|cit137","doi-asserted-by":"crossref","first-page":"79","DOI":"10.4269\/ajtmh.2005.73.79","article-title":"Successful treatment of refractory cutaneous leishmaniasis with GM-CSF and antimonials","volume":"73","author":"Almeida","year":"2005","journal-title":"American Journal of Tropical Medicine and Hygiene"},{"issue":"3","key":"10.1002\/14651858.CD004834.pub3-BIB0138|cit138","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1590\/S0365-05962011000300012","article-title":"Advances in the treatment of cutaneous leishmaniasis in the new world in the last ten years: a systematic literature review","volume":"86","author":"Almeida","year":"2011","journal-title":"Anais Brasileiros de Dermatologia"},{"issue":"5","key":"10.1002\/14651858.CD004834.pub3-BIB0139|cit139","doi-asserted-by":"crossref","first-page":"e35671","DOI":"10.1371\/journal.pone.0035671","article-title":"Leishmaniasis worldwide and global estimates of its incidence","volume":"7","author":"Alvar","year":"2012","journal-title":"PLOS One"},{"issue":"Suppl 2","key":"10.1002\/14651858.CD004834.pub3-BIB0140|cit140","doi-asserted-by":"crossref","first-page":"B244","DOI":"10.1016\/j.vaccine.2012.11.080","article-title":"Case study for a vaccine against leishmaniasis","volume":"31","author":"Alvar","year":"2013","journal-title":"Vaccine"},{"issue":"2","key":"10.1002\/14651858.CD004834.pub3-BIB0141|cit141","doi-asserted-by":"crossref","first-page":"266","DOI":"10.4269\/ajtmh.2007.77.266","article-title":"Treatment of mucosal leishmaniasis in Latin America: systematic review","volume":"77","author":"Amato","year":"2007","journal-title":"American Journal of Tropical Medicine and Hygiene"},{"issue":"1","key":"10.1002\/14651858.CD004834.pub3-BIB0142|cit142","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1590\/S0037-86822006000100004","article-title":"Clinical findings of tegumentary leishmaniasis in children under five years of age in an endemic area of Leishmania (Viannia) braziliensis","volume":"39","author":"Ampuero","year":"2006","journal-title":"Revista da Sociedade Brasileira de Medicina Tropical"},{"issue":"12","key":"10.1002\/14651858.CD004834.pub3-BIB0143|cit143","doi-asserted-by":"crossref","first-page":"1549","DOI":"10.1086\/518172","article-title":"Role of imiquimod and parenteral meglumine antimoniate in the initial treatment of cutaneous leishmaniasis","volume":"44","author":"Arevalo","year":"2007","journal-title":"Clinical Infectious Diseases"},{"issue":"12","key":"10.1002\/14651858.CD004834.pub3-BIB0144|cit144","doi-asserted-by":"crossref","first-page":"e202","DOI":"10.1093\/cid\/ciw670","article-title":"Diagnosis and treatment of leishmaniasis: clinical practice guidelines by the Infectious Diseases Society of America (IDSA) and the American Society of Tropical Medicine and Hygiene (ASTMH)","volume":"63","author":"Aronson","year":"2016","journal-title":"Clinical Infectious Diseases"},{"issue":"4","key":"10.1002\/14651858.CD004834.pub3-BIB0145|cit145","first-page":"223","article-title":"Successful use of a defined antigen\/GM-CSF adjuvant vaccine to treat mucosal Leishmaniasis refractory to antimony: a case report","volume":"5","author":"Badaro","year":"2001","journal-title":"Brazilian Journal of Infectious Diseases"},{"issue":"7","key":"10.1002\/14651858.CD004834.pub3-BIB0146|cit146","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1111\/j.1365-4362.1995.tb00613.x","article-title":"Polar and subpolar diffuse cutaneous leishmaniasis in Brazil: clinical and immunopathologic aspects","volume":"34","author":"Barral","year":"1995","journal-title":"International Journal of Dermatolology"},{"issue":"5","key":"10.1002\/14651858.CD004834.pub3-BIB0147|cit147","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1097\/00004630-199509000-00013","article-title":"The Vancouver Scar Scale: an administration tool and its interrater reliability","volume":"16","author":"Baryza","year":"1995","journal-title":"Journal of Burn Care & Rehabilitation"},{"issue":"3","key":"10.1002\/14651858.CD004834.pub3-BIB0148|cit148","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1016\/j.trsl.2013.03.006","article-title":"New vaccines for neglected parasitic diseases and dengue","volume":"162","author":"Beaumier","year":"2013","journal-title":"Translational Research"},{"issue":"3","key":"10.1002\/14651858.CD004834.pub3-BIB0149|cit149","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1007\/s004360050529","article-title":"The efficacy of pentamidine combined with allopurinol and immunotherapy for the treatment of patients with diffuse cutaneous leishmaniasis","volume":"85","author":"Becker","year":"1999","journal-title":"Parasitology Research"},{"key":"10.1002\/14651858.CD004834.pub3-BIB0150|cit150","doi-asserted-by":"crossref","first-page":"318","DOI":"10.4269\/ajtmh.1981.30.318","article-title":"Effect of temperature on multiplication of Leishmania amastigotes within monocyte-derived macrophages in vitro","volume":"30","author":"Berman","year":"1981","journal-title":"American Journal of Tropical Medicine and Hygiene"},{"issue":"10","key":"10.1002\/14651858.CD004834.pub3-BIB0151|cit151","doi-asserted-by":"crossref","first-page":"e313","DOI":"10.1371\/journal.pntd.0000313","article-title":"Complexities of assessing the disease burden attributable to leishmaniasis","volume":"2","author":"Bern","year":"2008","journal-title":"PLoS Neglected Tropical Diseases"},{"issue":"9587","key":"10.1002\/14651858.CD004834.pub3-BIB0152|cit152","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1016\/S0140-6736(07)61301-4","article-title":"Neglected diseases, civil conflicts, and the right to health","volume":"370","author":"Beyrer","year":"2007","journal-title":"Lancet"},{"issue":"682","key":"10.1002\/14651858.CD004834.pub3-BIB0153|cit153","first-page":"385","article-title":"Synthesis of 70 case histories of cutaneous leishmaniasis of Mexico (ulcer of the chicle gatherers)","volume":"33","author":"Biagi","year":"1953","journal-title":"Medicina (Mex)"},{"issue":"6","key":"10.1002\/14651858.CD004834.pub3-BIB0154|cit154","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1001\/archderm.139.6.795","article-title":"Appraising systematic reviews and meta-analyses","volume":"139","author":"Bigby","year":"2003","journal-title":"Archives of Dermatology"},{"issue":"6","key":"10.1002\/14651858.CD004834.pub3-BIB0155|cit155","doi-asserted-by":"crossref","first-page":"847","DOI":"10.4269\/ajtmh.2008.79.847","article-title":"Optimization of microculture and evaluation of miniculture for the isolation of Leishmania parasites from cutaneous lesions in Peru","volume":"79","author":"Boggild","year":"2008","journal-title":"American Journal of Tropical Medicine and Hygiene"},{"issue":"2","key":"10.1002\/14651858.CD004834.pub3-BIB0156|cit156","doi-asserted-by":"crossref","first-page":"345","DOI":"10.4269\/ajtmh.2010.09-0414","article-title":"Clinical and demographic stratification of test performance: a pooled analysis of five laboratory diagnostic methods for American cutaneous leishmaniasis","volume":"83","author":"Boggild","year":"2010","journal-title":"American Journal of Tropical Medicine and Hygiene"},{"issue":"5","key":"10.1002\/14651858.CD004834.pub3-BIB0157|cit157","doi-asserted-by":"crossref","first-page":"854","DOI":"10.4269\/ajtmh.2007.77.854","article-title":"Cellular analysis of cutaneous leishmaniasis lymphadenopathy: insights into the early phases of human disease","volume":"77","author":"Bomfim","year":"2007","journal-title":"American Journal of Tropical Medicine and Hygiene"},{"issue":"9","key":"10.1002\/14651858.CD004834.pub3-BIB0158|cit158","doi-asserted-by":"crossref","first-page":"e0184777","DOI":"10.1371\/journal.pone.0184777","article-title":"Efficacy of pentavalent antimoniate intralesional infiltration therapy for cutaneous leishmaniasis: A systematic review","volume":"12","author":"Brito","year":"2017","journal-title":"PLoS One"},{"issue":"6","key":"10.1002\/14651858.CD004834.pub3-BIB0159|cit159","doi-asserted-by":"crossref","first-page":"1485","DOI":"10.1086\/314782","article-title":"Treatment of experimental leishmaniasis with the immunomodulators imiquimod and S-28463: efficacy and mode of action","volume":"179","author":"Buates","year":"1999","journal-title":"Journal of Infectious Diseases"},{"issue":"5","key":"10.1002\/14651858.CD004834.pub3-BIB0160|cit160","doi-asserted-by":"crossref","first-page":"e0122569","DOI":"10.1371\/journal.pone.0122569","article-title":"Efficacy of thermotherapy to treat cutaneous leishmaniasis: a meta-analysis of controlled clinical trials","volume":"10","author":"Cardona-Arias","year":"2015","journal-title":"PLOS One"},{"issue":"1","key":"10.1002\/14651858.CD004834.pub3-BIB0161|cit161","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1093\/infdis\/jiv020","article-title":"Interleukin 10-dominant immune response and increased risk of cutaneous leishmaniasis after natural exposure to lutzomyia intermedia sand flies","volume":"212","author":"Carvalho","year":"2015","journal-title":"Journal of Infectious Diseases"},{"issue":"1","key":"10.1002\/14651858.CD004834.pub3-BIB0162|cit162","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1111\/j.1365-4632.2004.02429.x","article-title":"Cutaneous leishmaniasis: successful treatment with itraconazole","volume":"45","author":"Consigli","year":"2006","journal-title":"International Journal of Dermatolology"},{"issue":"6","key":"10.1002\/14651858.CD004834.pub3-BIB0163|cit163","first-page":"319","article-title":"Disseminated cutaneous leishmaniasis in a field clinic in Bahia, Brazil: a report of eight cases","volume":"89","author":"Costa","year":"1986","journal-title":"Journal of Tropical and Medicine Hygiene"},{"issue":"2","key":"10.1002\/14651858.CD004834.pub3-BIB0164|cit164","doi-asserted-by":"crossref","first-page":"e0149697","DOI":"10.1371\/journal.pone.0149697","article-title":"The cure rate after placebo or no therapy in American cutaneous leishmaniasis: a systematic review and meta-analysis","volume":"11","author":"Cota","year":"2016","journal-title":"PLOS One"},{"key":"10.1002\/14651858.CD004834.pub3-BIB0165|cit165","unstructured":"Veritas Health Innovation Covidence"},{"issue":"2","key":"10.1002\/14651858.CD004834.pub3-BIB0166|cit166","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1006\/faat.1997.2392","article-title":"Ketoconazole impairs early pregnancy and the decidual cell response via alterations in ovarian function","volume":"40","author":"Cummings","year":"1997","journal-title":"Fundamental and Applied Toxicology"},{"issue":"3","key":"10.1002\/14651858.CD004834.pub3-BIB0167|cit167","doi-asserted-by":"crossref","first-page":"296","DOI":"10.4269\/ajtmh.1994.50.296","article-title":"A general classification of New World Leishmania using numerical zymotaxonomy","volume":"50","author":"Cupolillo","year":"1994","journal-title":"American Journal of Tropical Medicine and Hygiene"},{"issue":"1-2","key":"10.1002\/14651858.CD004834.pub3-BIB0168|cit168","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1007\/s004300100080","article-title":"Recent advances in the taxonomy of the New World leishmanial parasites","volume":"190","author":"Cupolillo","year":"2001","journal-title":"Medical Microbiology and Immunology"},{"issue":"2","key":"10.1002\/14651858.CD004834.pub3-BIB0169|cit169","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1590\/0074-0276130312","article-title":"Comparative analysis of the tissue inflammatory response in human cutaneous and disseminated leishmaniasis","volume":"109","author":"Dantas","year":"2014","journal-title":"Mem\u00f3rias do Instituto Oswaldo Cruz"},{"issue":"1","key":"10.1002\/14651858.CD004834.pub3-BIB0170|cit170","doi-asserted-by":"crossref","first-page":"85","DOI":"10.4269\/ajtmh.1997.56.85","article-title":"Cutaneous leishmaniasis in the Peruvian Andes: risk factors identified from a village cohort study","volume":"56","author":"Davies","year":"1997","journal-title":"American Journal of Tropical Medicine and Hygiene"},{"issue":"4","key":"10.1002\/14651858.CD004834.pub3-BIB0171|cit171","first-page":"925","article-title":"The epidemiology and control of leishmaniasis in Andean countries","volume":"16","author":"Davies","year":"2000","journal-title":"Cadernos de Saude Publica \/ Ministerio da Saude, Fundacao Oswaldo Cruz, Escola Nacional de Saude Publica"},{"issue":"7","key":"10.1002\/14651858.CD004834.pub3-BIB0172|cit172","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1016\/j.trstmh.2008.11.019","article-title":"Cutaneous leishmaniasis due to Leishmania chagasi\/Le. infantum in an endemic area of Guarico State, Venezuela","volume":"103","author":"De Lima","year":"2009","journal-title":"Transactions of the Royal Society of Tropical Medicine and Hygiene"},{"issue":"12","key":"10.1002\/14651858.CD004834.pub3-BIB0173|cit173","doi-asserted-by":"crossref","first-page":"e83247","DOI":"10.1371\/journal.pone.0083247","article-title":"In vitro activity of the antifungal azoles itraconazole and posaconazole against Leishmania amazonensis","volume":"8","author":"De Macedo-Silva","year":"2013","journal-title":"PLOS One"},{"key":"10.1002\/14651858.CD004834.pub3-BIB0174|cit174","doi-asserted-by":"crossref","unstructured":"Deeks JJ Higgins JP Chapter 10: Analysing data and undertaking meta-analyses. In: Higgins JP, Thomas J, Chandler J, Cumpston M, Li T, Page MJ, et al (editors). Cochrane Handbook for Systematic Reviews of Interventions version 6.0 (updated July 2019). The Cochrane Collaboration, 2019 Available from www.training.cochrane.org\/handbook","DOI":"10.1002\/9781119536604.ch10"},{"issue":"2","key":"10.1002\/14651858.CD004834.pub3-BIB0175|cit175","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1016\/j.vaccine.2011.11.005","article-title":"The development and clinical evaluation of second-generation leishmaniasis vaccines","volume":"30","author":"Duthie","year":"2012","journal-title":"Vaccine"},{"issue":"1 Pt 2","key":"10.1002\/14651858.CD004834.pub3-BIB0176|cit176","doi-asserted-by":"crossref","first-page":"S12","DOI":"10.1067\/mjd.2000.107806","article-title":"Imiquimod in clinical practice","volume":"43","author":"Edwards","year":"2000","journal-title":"Journal of the American Academy of Dermatology"},{"issue":"7109","key":"10.1002\/14651858.CD004834.pub3-BIB0177|cit177","doi-asserted-by":"crossref","first-page":"629-34","DOI":"10.1136\/bmj.315.7109.629","article-title":"Bias in meta-analysis detected by a simple, graphical test","volume":"315","author":"Egger","year":"1997","journal-title":"BMJ"},{"issue":"5","key":"10.1002\/14651858.CD004834.pub3-BIB0178|cit178","doi-asserted-by":"crossref","first-page":"1364","DOI":"10.1111\/bjd.13490","article-title":"Cutaneous leishmaniasis responds to daylight-activated photodynamic therapy: proof of concept for a novel self-administered therapeutic modality","volume":"172","author":"Enk","year":"2015","journal-title":"British Journal of Dermatology"},{"issue":"5","key":"10.1002\/14651858.CD004834.pub3-BIB0179|cit179","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1111\/j.1600-0781.2011.00610.x","article-title":"Successful treatment of cutaneous leishmaniasis with intralesional aminolevulinic acid photodynamic therapy","volume":"27","author":"Evangelou","year":"2011","journal-title":"Photodermatology, Photoimmunology and Photomedicine"},{"key":"10.1002\/14651858.CD004834.pub3-BIB0180|cit180","unstructured":"Use of long-term, high-dose Diflucan (fluconazole) during pregnancy may be associated with birth defects in infants www.fda.gov\/Drugs\/DrugSafety\/ucm266030.htm"},{"key":"10.1002\/14651858.CD004834.pub3-BIB0181|cit181","unstructured":"Nizoral (ketoconazole) oral tablets: Potentially fatal liver injury, risk of drug interactions and adrenal gland problems www.fda.gov\/drugs\/drug-safety-and-availability\/fda-drug-safety-communication-fda-limits-usage-nizoral-ketoconazole-oral-tablets-due-potentially"},{"key":"10.1002\/14651858.CD004834.pub3-BIB0182|cit182","unstructured":"Sporanox (itraconazole) Oral Solution - Detailed view: Safety labeling changes approved by FDA Center for Drug Evaluation and Research (CDER) www.accessdata.fda.gov\/drugsatfda_docs\/label\/2012\/020657s027lbl.pdf"},{"key":"10.1002\/14651858.CD004834.pub3-BIB0183|cit183","unstructured":"FDA evaluating study examining use of oral fluconazole (Diflucan) in pregnancy www.fda.gov\/drugs\/drug-safety-and-availability\/fda-drug-safety-communication-fda-review-study-examining-use-oral-fluconazole-diflucan-pregnancy"},{"issue":"5","key":"10.1002\/14651858.CD004834.pub3-BIB0184|cit184","doi-asserted-by":"crossref","first-page":"e2871","DOI":"10.1371\/journal.pntd.0002871","article-title":"Miltefosine and antimonial drug susceptibility of Leishmania Viannia species and populations in regions of high transmission in Colombia","volume":"8","author":"Fernandez","year":"2014","journal-title":"PLOS Neglected Tropical Diseases"},{"issue":"6","key":"10.1002\/14651858.CD004834.pub3-BIB0185|cit185","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1590\/0037-8682-0104-2013","article-title":"Treatment of American tegumentary leishmaniasis in special populations: a summary of evidence","volume":"46","author":"Fontenele e Silva","year":"2013","journal-title":"Revista da Sociedade Brasileira de Medicina Tropical"},{"issue":"2","key":"10.1002\/14651858.CD004834.pub3-BIB0186|cit186","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1016\/j.diagmicrobio.2012.06.010","article-title":"Accurate and rapid species typing from cutaneous and mucocutaneous leishmaniasis lesions of the New World","volume":"74","author":"Fraga","year":"2012","journal-title":"Diagnostic Microbiology and Infectious Disease"},{"issue":"2","key":"10.1002\/14651858.CD004834.pub3-BIB0187|cit187","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1093\/clinids\/12.2.308","article-title":"Amphotericin B: 30 years of clinical experience","volume":"12","author":"Gallis","year":"1990","journal-title":"Revews of Infectious Diseases"},{"issue":"10","key":"10.1002\/14651858.CD004834.pub3-BIB0188|cit188","doi-asserted-by":"crossref","first-page":"e0186117","DOI":"10.1371\/journal.pone.0186117","article-title":"Efficacy of azole therapy for tegumentary leishmaniasis: a systematic review and meta-analysis","volume":"12","author":"Galv\u00e3o","year":"2017","journal-title":"PLOS One"},{"key":"10.1002\/14651858.CD004834.pub3-BIB0189|cit189","doi-asserted-by":"crossref","unstructured":"Galv\u00e3o EL Pedras MJ Cota GF Sim\u00f5es TC Rabello A Development and initial validation of a cutaneous leishmaniasis impact questionnaire PLOS One 2018 13 8 e0203378","DOI":"10.1371\/journal.pone.0203378"},{"issue":"1","key":"10.1002\/14651858.CD004834.pub3-BIB0190|cit190","doi-asserted-by":"crossref","first-page":"e0211374","DOI":"10.1371\/journal.pone.0211374","article-title":"How cutaneous leishmaniasis and treatment impacts in the patients' lives: a cross-sectional study","volume":"14","author":"Galv\u00e3o","year":"2019","journal-title":"PLOS One"},{"issue":"2","key":"10.1002\/14651858.CD004834.pub3-BIB0191|cit191","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1590\/0074-02760140280","article-title":"Accuracy of mucocutaneous leishmaniasis diagnosis using polymerase chain reaction: systematic literature review and meta-analysis","volume":"110","author":"Gomes","year":"2015","journal-title":"Mem\u00f3rias do Instituto Oswaldo Cruz"},{"issue":"4","key":"10.1002\/14651858.CD004834.pub3-BIB0192|cit192","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1086\/655134","article-title":"Designing and reporting clinical trials on treatments for cutaneous leishmaniasis","volume":"51","author":"Gonz\u00e1lez","year":"2010","journal-title":"Clinical Infectious Diseases"},{"issue":"8","key":"10.1002\/14651858.CD004834.pub3-BIB0193|cit193","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD008736.pub2","article-title":"Vector and reservoir control for preventing leishmaniasis","author":"Gonz\u00e1lez","year":"2015","journal-title":"Cochrane Database of Systematic Reviews"},{"issue":"5","key":"10.1002\/14651858.CD004834.pub3-BIB0194|cit194","doi-asserted-by":"crossref","first-page":"664","DOI":"10.1590\/S0074-02762012000500014","article-title":"Development and validation of PCR-based assays for diagnosis of American cutaneous leishmaniasis and identification of the parasite species","volume":"107","author":"Graca","year":"2012","journal-title":"Mem\u00f3rias do Instituto Oswaldo Cruz"},{"issue":"7650","key":"10.1002\/14651858.CD004834.pub3-BIB0195|cit195","doi-asserted-by":"crossref","first-page":"924","DOI":"10.1136\/bmj.39489.470347.AD","article-title":"GRADE: an emerging consensus on rating quality of evidence and strength of recommendations","volume":"336","author":"Guyatt","year":"2008","journal-title":"BMJ"},{"issue":"6","key":"10.1002\/14651858.CD004834.pub3-BIB0196|cit196","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1016\/j.jaad.2014.08.051","article-title":"Cutaneous and mucocutaneous leishmaniasis: clinical perspectives","volume":"73","author":"Handler","year":"2015","journal-title":"Journal of the American Academy of Dermatology"},{"key":"10.1002\/14651858.CD004834.pub3-BIB0197|cit197","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1186\/s41182-016-0002-0","article-title":"Diffuse and disseminated cutaneous leishmaniasis: clinical cases experienced in Ecuador and a brief review","volume":"44","author":"Hashiguchi","year":"2016","journal-title":"Tropical Medicine and Health"},{"issue":"12","key":"10.1002\/14651858.CD004834.pub3-BIB0198|cit198","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD005067.pub5","article-title":"Interventions for Old World cutaneous leishmaniasis","author":"Heras-Mosteiro","year":"2017","journal-title":"Cochrane Database of Systematic Reviews"},{"issue":"7414","key":"10.1002\/14651858.CD004834.pub3-BIB0199|cit199","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1136\/bmj.327.7414.557","article-title":"Measuring inconsistency in meta-analyses","volume":"327","author":"Higgins","year":"2003","journal-title":"BMJ"},{"key":"10.1002\/14651858.CD004834.pub3-BIB0200|cit200","unstructured":"Higgins JP Green S Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 (updated March 2011). The Cochrane Collaboration, 2011 Available from handbook.cochrane.org"},{"issue":"6","key":"10.1002\/14651858.CD004834.pub3-BIB0201|cit201","doi-asserted-by":"crossref","first-page":"e66637","DOI":"10.1371\/journal.pone.0066637","article-title":"Allopurinol use during pregnancy - outcome of 31 prospectively ascertained cases and a phenotype possibly indicative for teratogenicity","volume":"8","author":"Hoeltzenbein","year":"2013","journal-title":"PLOS One"},{"key":"10.1002\/14651858.CD004834.pub3-BIB0202|cit202","doi-asserted-by":"crossref","unstructured":"Jin G Wong ST Toward better drug repositioning: prioritizing and integrating existing methods into efficient pipelines Drug Discovery Today 2014 19 5 637 44","DOI":"10.1016\/j.drudis.2013.11.005"},{"issue":"5","key":"10.1002\/14651858.CD004834.pub3-BIB0203|cit203","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1016\/S1473-3099(16)00003-7","article-title":"Global burden of cutaneous leishmaniasis: a cross-sectional analysis from the Global Burden of Disease Study 2013","volume":"16","author":"Karimkhani","year":"2016","journal-title":"Lancet Infectious Diseases"},{"issue":"2","key":"10.1002\/14651858.CD004834.pub3-BIB0204|cit204","doi-asserted-by":"crossref","first-page":"e381","DOI":"10.1371\/journal.pntd.0000381","article-title":"Is paromomycin an effective and safe treatment against cutaneous leishmaniasis? A meta-analysis of 14 randomized controlled trials","volume":"3","author":"Kim","year":"2009","journal-title":"PLOS Neglected Tropical Diseases"},{"issue":"3","key":"10.1002\/14651858.CD004834.pub3-BIB0205|cit205","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1590\/S0074-02761994000300027","article-title":"The dermal leishmaniases of Brazil, with special reference to the eco-epidemiology of the disease in Amazonia","volume":"89","author":"Lainson","year":"1994","journal-title":"Mem\u00f3rias do Instituto Oswaldo Cruz"},{"issue":"1","key":"10.1002\/14651858.CD004834.pub3-BIB0206|cit206","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1038\/sj.cdd.4400952","article-title":"Programmed cell death in the unicellular protozoan parasite Leishmania","volume":"9","author":"Lee","year":"2002","journal-title":"Cell Death Differentiation"},{"issue":"6","key":"10.1002\/14651858.CD004834.pub3-BIB0207|cit207","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1016\/j.trstmh.2012.03.007","article-title":"A proposed new clinical staging system for patients with mucosal leishmaniasis","volume":"106","author":"Lessa","year":"2012","journal-title":"Transactions of the Royal Society of Tropical Medicine and Hygiene"},{"issue":"2","key":"10.1002\/14651858.CD004834.pub3-BIB0208|cit208","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1086\/524042","article-title":"Clinical and parasite species risk factors for pentavalent antimonial treatment failure in cutaneous leishmaniasis in Peru","volume":"46","author":"Llanos-Cuentas","year":"2008","journal-title":"Clinical Infectious Diseases"},{"key":"10.1002\/14651858.CD004834.pub3-BIB0209|cit209","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1186\/1745-6215-13-58","article-title":"Thermotherapy. An alternative for the treatment of American cutaneous leishmaniasis","volume":"13","author":"Lopez","year":"2012","journal-title":"Trials"},{"key":"10.1002\/14651858.CD004834.pub3-BIB0210|cit210","doi-asserted-by":"publisher","first-page":"360","DOI":"10.1186\/s12879-016-1663-3","article-title":"Efficacy of cryotherapy for the treatment of cutaneous leishmaniasis: meta-analyses of clinical trials","volume":"16","author":"L\u00f3pez-Carvajal","year":"2016","journal-title":"BMC Infectous Diseases"},{"issue":"6","key":"10.1002\/14651858.CD004834.pub3-BIB0211|cit211","doi-asserted-by":"crossref","first-page":"945","DOI":"10.1093\/cid\/civ416","article-title":"Treatment of disseminated leishmaniasis with liposomal amphotericin B","volume":"61","author":"Machado","year":"2015","journal-title":"Clinical Infectious Diseases"},{"issue":"6 Pt A","key":"10.1002\/14651858.CD004834.pub3-BIB0212|cit212","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1016\/j.tmaid.2014.09.007","article-title":"Leishmaniasis in travelers: a literature review","volume":"12","author":"Mansueto","year":"2014","journal-title":"Travel Medicine and Infectious Disease"},{"issue":"7","key":"10.1002\/14651858.CD004834.pub3-BIB0213|cit213","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1056\/NEJM197902153000706","article-title":"Current concepts in parasitology. Leishmaniasis","volume":"300","author":"Marsden","year":"1979","journal-title":"New England Journal of Medicine"},{"issue":"2","key":"10.1002\/14651858.CD004834.pub3-BIB0214|cit214","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1590\/S0037-86821994000200007","article-title":"Mucosal leishmaniasis due to Leishmania (Viannia) braziliensis L(V)b in Tres Bracos, Bahia-Brazil","volume":"27","author":"Marsden","year":"1994","journal-title":"Revista da Sociedade Brasileira de Medicina Tropical"},{"issue":"4","key":"10.1002\/14651858.CD004834.pub3-BIB0215|cit215","doi-asserted-by":"crossref","first-page":"543","DOI":"10.4269\/ajtmh.1998.59.543","article-title":"Clinical observations of unresponsive mucosal leishmaniasis","volume":"59","author":"Marsden","year":"1998","journal-title":"American Journal of Tropical Medicine and Hygiene"},{"issue":"10","key":"10.1002\/14651858.CD004834.pub3-BIB0216|cit216","doi-asserted-by":"crossref","first-page":"1153","DOI":"10.2174\/092986707780362862","article-title":"Chemotherapy of leishmaniasis: past, present and future","volume":"14","author":"Mishra","year":"2007","journal-title":"Current Medicinal Chemistry"},{"key":"10.1002\/14651858.CD004834.pub3-BIB0217|cit217","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1186\/1475-9292-6-3","article-title":"Consultative meeting to develop a strategy for treatment of cutaneous leishmaniasis. Institute Pasteur, Paris. 13-15 June, 2006","volume":"6","author":"Modabber","year":"2006","journal-title":"Kinetoplastid Biology and Disease"},{"issue":"12","key":"10.1002\/14651858.CD004834.pub3-BIB0218|cit218","doi-asserted-by":"crossref","first-page":"e0004294","DOI":"10.1371\/journal.pntd.0004294","article-title":"Correction: Severity of Old World cutaneous leishmaniasis Is influenced by previous exposure to sandfly bites in Saudi Arabia","volume":"9","author":"Mondragon-Shem","year":"2015","journal-title":"PLoS Neglected Tropical Diseases"},{"issue":"5","key":"10.1002\/14651858.CD004834.pub3-BIB0219|cit219","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1590\/S0037-86822009000500007","article-title":"Population mobility and production of American tegumentary leishmaniasis in the State of Parana, southern Brazil","volume":"42","author":"Monteiro","year":"2009","journal-title":"Revista da Sociedade Brasileira de Medicina Tropical"},{"issue":"7","key":"10.1002\/14651858.CD004834.pub3-BIB0220|cit220","doi-asserted-by":"crossref","first-page":"228","DOI":"10.5712\/rbmfc2(7)58","article-title":"American tegumentary leishmaniasis: fluconazole therapy","volume":"2","author":"Neto","year":"2006","journal-title":"Revista Brasileira de Medicina de Fam\u00edlia e Comunidade"},{"issue":"2","key":"10.1002\/14651858.CD004834.pub3-BIB0221|cit221","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/j.actatropica.2011.02.007","article-title":"Systematic review of the adverse effects of cutaneous leishmaniasis treatment in the New World","volume":"118","author":"Oliveira","year":"2011","journal-title":"Acta Tropica"},{"key":"10.1002\/14651858.CD004834.pub3-BIB0222|cit222","doi-asserted-by":"crossref","first-page":"396894","DOI":"10.1155\/2015\/396894","article-title":"Development, characterization, and in vitro biological performance of fluconazole-loaded microemulsions for the topical treatment of cutaneous leishmaniasis","volume":"2015","author":"Oliveira","year":"2015","journal-title":"BioMed Research International"},{"issue":"3","key":"10.1002\/14651858.CD004834.pub3-BIB0223|cit223","doi-asserted-by":"crossref","first-page":"e2130","DOI":"10.1371\/journal.pntd.0002130","article-title":"Methodology of clinical trials aimed at assessing interventions for cutaneous leishmaniasis","volume":"7","author":"Olliaro","year":"2013","journal-title":"PLOS Neglected Tropical Diseases"},{"key":"10.1002\/14651858.CD004834.pub3-BIB0224|cit224","doi-asserted-by":"crossref","unstructured":"Olliaro P Grogl M Boni M Carvalho EM Chebli H Cisse M Harmonized clinical trial methodologies for localized cutaneous leishmaniasis and potential for extensive network with capacities for clinical evaluation PLOS Neglected Tropical Diseases 2018 12 1 e0006141","DOI":"10.1371\/journal.pntd.0006141"},{"issue":"1","key":"10.1002\/14651858.CD004834.pub3-BIB0225|cit225","doi-asserted-by":"crossref","first-page":"49","DOI":"10.4269\/ajtmh.1998.59.49","article-title":"Mucosal leishmaniasis due to Leishmania (Viannia) panamensis in Colombia: clinical characteristics","volume":"59","author":"Osorio","year":"1998","journal-title":"American Journal of Tropical Medicine and Hygiene"},{"key":"10.1002\/14651858.CD004834.pub3-BIB0226|cit226","doi-asserted-by":"crossref","unstructured":"Page MJ Higgins JP Sterne JA Chapter 13: Assessing risk of bias due to missing results in a synthesis. In: Higgins JP, Thomas J, Chandler J, Cumpston M, Li T, Page MJ, et al (editors). Cochrane Handbook for Systematic Reviews of Interventions version 6.0 (updated July 2019). The Cochrane Collaboration, 2019 Available from www.training.cochrane.org\/handbook","DOI":"10.1002\/9781119536604.ch13"},{"key":"10.1002\/14651858.CD004834.pub3-BIB0227|cit227","unstructured":"Pan American Health Organization Leishmaniasis in the Americas: Treatment recommendations www.paho.org\/hq\/index.php?option=com_topics&view=rdmore&cid=6123&item=leishmaniasis&cat=scientific_technical&type=guidelines-6123&Itemid=40754&lang=en"},{"key":"10.1002\/14651858.CD004834.pub3-BIB0228|cit228","unstructured":"Pan American Health Organization Leishmaniasis in the Americas: Treatment recommendations www.paho.org\/hq\/index.php?option=com_topics&view=rdmore&cid=6123&item=leishmaniasis&cat=scientific_technical&type=guidelines-6123&Itemid=40754&lang=en"},{"key":"10.1002\/14651858.CD004834.pub3-BIB0229|cit229","unstructured":"Pan American Health Organization Leishmaniasis: Epidemiological Report in the Americas iris.paho.org\/xmlui\/bitstream\/handle\/123456789\/50505\/Leishreport2019_eng.pdf"},{"key":"10.1002\/14651858.CD004834.pub3-BIB0230|cit230","volume-title":"Manual of Procedures for Leishmaniases Surveillance and Control in the Americas","author":"Pan American Health Organization","year":"2019"},{"issue":"7","key":"10.1002\/14651858.CD004834.pub3-BIB0231|cit231","doi-asserted-by":"publisher","first-page":"433","DOI":"10.1590\/0074-02760160074","article-title":"Spatial modeling of cutaneous leishmaniasis in the Andean region of Colombia","volume":"111","author":"Perez-Florez","year":"2016","journal-title":"Mem\u00f3rias do Instituto Oswaldo Cruz"},{"issue":"9","key":"10.1002\/14651858.CD004834.pub3-BIB0232|cit232","doi-asserted-by":"crossref","first-page":"919","DOI":"10.1016\/S0020-7519(03)00094-8","article-title":"Lutzomyia vectors for cutaneous leishmaniasis in Southern Brazil: ecological niche models, predicted geographic distributions, and climate change effects","volume":"33","author":"Peterson","year":"2003","journal-title":"International Journal of Parasitology"},{"issue":"1","key":"10.1002\/14651858.CD004834.pub3-BIB0233|cit233","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1186\/1475-9292-2-14","article-title":"Physiological consequences of drug resistance in Leishmania and their relevance for chemotherapy","volume":"2","author":"Ponte-Sucre","year":"2003","journal-title":"Kinetoplastid Biology and Disease"},{"issue":"5","key":"10.1002\/14651858.CD004834.pub3-BIB0234|cit234","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1590\/0037-8682-0132-2015","article-title":"Polymerase chain reaction-based method for the identification of Leishmania (Viannia) braziliensis and Leishmania (Viannia) guyanensis in mucosal tissues conserved in paraffin","volume":"48","author":"Prestes","year":"2015","journal-title":"Revista da Sociedade Brasileira de Medicina Tropical"},{"issue":"1","key":"10.1002\/14651858.CD004834.pub3-BIB0235|cit235","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1007\/s002329900086","article-title":"Amphotericin B kills unicellular leishmanias by forming aqueous pores permeable to small cations and anions","volume":"152","author":"Ramos","year":"1996","journal-title":"Journal of Membrane Biology"},{"issue":"1","key":"10.1002\/14651858.CD004834.pub3-BIB0236|cit236","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1586\/14760584.2016.1105135","article-title":"Leishmania vaccine development: exploiting the host-vector-parasite interface","volume":"15","author":"Reed","year":"2016","journal-title":"Expert Review of Vaccines"},{"issue":"4","key":"10.1002\/14651858.CD004834.pub3-BIB0237|cit237","doi-asserted-by":"crossref","first-page":"e61843","DOI":"10.1371\/journal.pone.0061843","article-title":"Interventions for American cutaneous and mucocutaneous leishmaniasis: a systematic review update","volume":"8","author":"Reveiz","year":"2013","journal-title":"PLOS One"},{"key":"10.1002\/14651858.CD004834.pub3-BIB0238|cit238","unstructured":"Nordic Cochrane Centre, The Cochrane Collaboration Review Manager 5 (RevMan 5) 2014"},{"issue":"4","key":"10.1002\/14651858.CD004834.pub3-BIB0239|cit239","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1016\/S0035-9203(02)90375-5","article-title":"Surveillance and screening of American cutaneous leishmaniasis by Colombian primary health care workers using a clinical prediction rule","volume":"96","author":"Rojas","year":"2002","journal-title":"Transactions of the Royal Society of Tropical Medicine and Hygiene"},{"issue":"5","key":"10.1002\/14651858.CD004834.pub3-BIB0240|cit240","doi-asserted-by":"crossref","first-page":"456","DOI":"10.4269\/ajtmh.2001.65.456","article-title":"Comparison of cutaneous leishmaniasis due to Leishmania (Viannia) braziliensis and L. (V.) guyanensis in Brazil: therapeutic response to meglumine antimoniate","volume":"65","author":"Romero","year":"2001","journal-title":"American Journal of Tropical Medicine and Hygiene"},{"issue":"9","key":"10.1002\/14651858.CD004834.pub3-BIB0241|cit241","doi-asserted-by":"crossref","first-page":"1304","DOI":"10.1086\/319990","article-title":"Comparison of cutaneous leishmaniasis due to Leishmania (Viannia) braziliensis and L. (V.) guyanensis in Brazil: clinical findings and diagnostic approach","volume":"32","author":"Romero","year":"2001","journal-title":"Clinical Infectious Diseases"},{"issue":"1","key":"10.1002\/14651858.CD004834.pub3-BIB0242|cit242","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.actatropica.2004.09.005","article-title":"Antibody response in patients with cutaneous leishmaniasis infected by Leishmania (Viannia) braziliensis or Leishmania (Viannia) guyanensis in Brazil","volume":"93","author":"Romero","year":"2005","journal-title":"Acta Tropica"},{"issue":"2","key":"10.1002\/14651858.CD004834.pub3-BIB0243|cit243","doi-asserted-by":"crossref","first-page":"300","DOI":"10.4269\/ajtmh.1983.32.300","article-title":"Thermosensitivity patterns of Old vs. New World cutaneous strains of Leishmania growing within mouse peritoneal macrophages in vitro","volume":"32","author":"Sacks","year":"1983","journal-title":"American Journal of Tropical Medicine and Hygiene"},{"issue":"12","key":"10.1002\/14651858.CD004834.pub3-BIB0244|cit244","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1046\/j.1365-3156.1999.00491.x","article-title":"Treatment of two patients with diffuse cutaneous leishmaniasis caused by Leishmania mexicana modifies the immunohistological profile but not the disease outcome","volume":"4","author":"Salaiza-Suazo","year":"1999","journal-title":"Tropical Medicine and International Health"},{"issue":"5","key":"10.1002\/14651858.CD004834.pub3-BIB0245|cit245","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1093\/clinids\/7.5.625","article-title":"Pentamidine: a review","volume":"7","author":"Sands","year":"1985","journal-title":"Reviews of Infectious Diseases"},{"issue":"1","key":"10.1002\/14651858.CD004834.pub3-BIB0246|cit246","doi-asserted-by":"crossref","first-page":"51","DOI":"10.4269\/ajtmh.1990.42.51","article-title":"Mucosal disease caused by Leishmania braziliensis guyanensis","volume":"42","author":"Santrich","year":"1990","journal-title":"American Journal of Tropical Medicine and Hygiene"},{"issue":"6","key":"10.1002\/14651858.CD004834.pub3-BIB0247|cit247","doi-asserted-by":"crossref","first-page":"e283","DOI":"10.1371\/journal.pmed.0030283","article-title":"Response from Savioli and colleagues from the Department of Neglected Tropical Diseases, World Health Organization","volume":"3","author":"Savioli","year":"2006","journal-title":"PLOS Medicine"},{"issue":"10","key":"10.1002\/14651858.CD004834.pub3-BIB0248|cit248","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1016\/j.pt.2010.06.013","article-title":"Is it time to revise the nomenclature of Leishmania?","volume":"26","author":"Schonian","year":"2010","journal-title":"Trends in Parasitology"},{"issue":"7","key":"10.1002\/14651858.CD004834.pub3-BIB0249|cit249","doi-asserted-by":"crossref","first-page":"2064","DOI":"10.1128\/AAC.45.7.2064-2069.2001","article-title":"Antimonial-mediated DNA fragmentation in Leishmania infantum amastigotes","volume":"45","author":"Sereno","year":"2001","journal-title":"Antimicrobial Agents and Chemotherapy"},{"issue":"9115","key":"10.1002\/14651858.CD004834.pub3-BIB0250|cit250","doi-asserted-by":"crossref","first-page":"1540","DOI":"10.1016\/S0140-6736(98)09552-X","article-title":"Randomised vaccine trial of single dose of killed Leishmania major plus BCG against anthroponotic cutaneous leishmaniasis in Bam, Iran","volume":"351","author":"Sharifi","year":"1998","journal-title":"Lancet"},{"issue":"Suppl 1","key":"10.1002\/14651858.CD004834.pub3-BIB0251|cit251","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1590\/S0074-02761988000500054","article-title":"Animal reservoirs of Leishmania in different ecological situations and their importance in the epidemiology of the disease","volume":"83","author":"Shaw","year":"1988","journal-title":"Mem\u00f3rias do Instituto Oswaldo Cruz"},{"issue":"7","key":"10.1002\/14651858.CD004834.pub3-BIB0252|cit252","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1093\/cid\/cir496","article-title":"High-dose oral fluconazole therapy effective for cutaneous leishmaniasis due to Leishmania (Vianna) braziliensis","volume":"53","author":"Sousa","year":"2011","journal-title":"Clinical Infectious Diseases"},{"issue":"27","key":"10.1002\/14651858.CD004834.pub3-BIB0253|cit253","doi-asserted-by":"crossref","first-page":"25120","DOI":"10.1074\/jbc.M301975200","article-title":"Antimonial-induced increase in intracellular Ca2+ through non-selective cation channels in the host and the parasite is responsible for apoptosis of intracellular Leishmania donovani amastigotes","volume":"278","author":"Sudhandiran","year":"2003","journal-title":"Journal of Biological Chemistry"},{"issue":"3","key":"10.1002\/14651858.CD004834.pub3-BIB0254|cit254","first-page":"345","article-title":"Visceral leishmaniasis-current therapeutic modalities","volume":"123","author":"Sundar","year":"2006","journal-title":"Indian Journal of Medicine Research"},{"issue":"5","key":"10.1002\/14651858.CD004834.pub3-BIB0255|cit255","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1517\/13543784.17.5.787","article-title":"Paromomycin in the treatment of leishmaniasis","volume":"17","author":"Sundar","year":"2008","journal-title":"Expert Opinion on Investigational Drugs"},{"issue":"9","key":"10.1002\/14651858.CD004834.pub3-BIB0256|cit256","doi-asserted-by":"crossref","first-page":"1388","DOI":"10.1111\/j.1365-3156.2006.01695.x","article-title":"Species diversity causing human cutaneous leishmaniasis in Rio Branco, state of Acre, Brazil","volume":"11","author":"Tojal da Silva","year":"2006","journal-title":"Tropical Medicine & International Health"},{"issue":"5","key":"10.1002\/14651858.CD004834.pub3-BIB0257|cit257","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1093\/trstmh\/trt021","article-title":"Assessment of the quality of life of patients with cutaneous leishmaniasis in Belo Horizonte, Brazil, 2009-2010. A pilot study","volume":"107","author":"Da Silva","year":"2013","journal-title":"Transactions of the Royal Society of Tropical Medicine"},{"key":"10.1002\/14651858.CD004834.pub3-BIB0258|cit258","volume-title":"The Pharmacological Basis of Therapeutics","author":"Tracy","year":"2001"},{"issue":"12","key":"10.1002\/14651858.CD004834.pub3-BIB0259|cit259","doi-asserted-by":"crossref","first-page":"1829","DOI":"10.1086\/345772","article-title":"Disseminated leishmaniasis: a new and emerging form of leishmaniasis observed in northeastern Brazil","volume":"186","author":"Turetz","year":"2002","journal-title":"Journal of Infectious Diseases"},{"issue":"8","key":"10.1002\/14651858.CD004834.pub3-BIB0260|cit260","doi-asserted-by":"crossref","first-page":"3010","DOI":"10.1128\/AAC.48.8.3010-3015.2004","article-title":"Possible mechanism of miltefosine-mediated death of Leishmania donovani","volume":"48","author":"Verma","year":"2004","journal-title":"Antimicrobial Agents and Chemotherapy"},{"issue":"3","key":"10.1002\/14651858.CD004834.pub3-BIB0261|cit261","doi-asserted-by":"crossref","first-page":"489","DOI":"10.4269\/ajtmh.1987.36.489","article-title":"Diagnosis of cutaneous and mucocutaneous leishmaniasis in Colombia: a comparison of seven methods","volume":"36","author":"Weigle","year":"1987","journal-title":"American Journal of Tropical Medicine and Hygiene"},{"issue":"3","key":"10.1002\/14651858.CD004834.pub3-BIB0262|cit262","doi-asserted-by":"crossref","first-page":"260","DOI":"10.4269\/ajtmh.1991.44.260","article-title":"Leishmanin skin test standardization and evaluation of safety, dose, storage, longevity of reaction and sensitization","volume":"44","author":"Weigle","year":"1991","journal-title":"American Journal of Tropical Medicine and Hygiene"},{"issue":"3","key":"10.1002\/14651858.CD004834.pub3-BIB0263|cit263","doi-asserted-by":"crossref","first-page":"548","DOI":"10.1093\/ije\/22.3.548","article-title":"A clinical prediction rule for American cutaneous leishmaniasis in Colombia","volume":"22","author":"Weigle","year":"1993","journal-title":"International Journal of Epidemiology"},{"key":"10.1002\/14651858.CD004834.pub3-BIB0264|cit264","unstructured":"World Health Organization Control of the leishmaniasis: report of a meeting of the WHO Expert Committee on the Control of Leishmaniases, Geneva, 22-26 March 2010 apps.who.int\/iris\/handle\/10665\/44412"},{"issue":"5","key":"10.1002\/14651858.CD004834.pub3-BIB0265|cit265","doi-asserted-by":"crossref","first-page":"1028","DOI":"10.4269\/ajtmh.2010.10-0171","article-title":"Lipsosomal amphotericin B for treatment of cutaneous leishmaniasis","volume":"83","author":"Wortmann","year":"2010","journal-title":"American Journal of Tropical Medicine and Hygiene"},{"issue":"5","key":"10.1002\/14651858.CD004834.pub3-BIB0266|cit266","doi-asserted-by":"crossref","first-page":"519","DOI":"10.4269\/ajtmh.2003.68.519","article-title":"Indoor and peridomestic transmission of American cutaneous leishmaniasis in northwestern Argentina: a retrospective case-control study","volume":"68","author":"Yadon","year":"2003","journal-title":"American Journal of Tropical Medicine and Hygiene"},{"issue":"16","key":"10.1002\/14651858.CD004834.pub3-BIB0267|cit267","first-page":"2925","article-title":"Photodynamic therapy of condyloma acuminata in pregnant women","volume":"125","author":"Yang","year":"2012","journal-title":"Chinese Medical Journal (Engl)"},{"issue":"9","key":"10.1002\/14651858.CD004834.pub3-BIB0268|cit268","doi-asserted-by":"crossref","first-page":"925","DOI":"10.1288\/00005537-198909000-00006","article-title":"Mucosal leishmaniasis in Brazil","volume":"99","author":"Zajtchuk","year":"1989","journal-title":"Laryngoscope"},{"issue":"3","key":"10.1002\/14651858.CD004834.pub3-BIB0269|cit269","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD004834","article-title":"Interventions for mucocutaneous leishmaniasis","author":"Gonz\u00e1lez","year":"2004","journal-title":"Cochrane Database of Systematic Reviews"},{"issue":"2","key":"10.1002\/14651858.CD004834.pub3-BIB0270|cit270","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD004834.pub2","article-title":"Interventions for American cutaneous and mucocutaneous leishmaniasis","author":"Gonz\u00e1lez","year":"2009","journal-title":"Cochrane Database of Systematic Reviews"}],"container-title":["Cochrane Database of Systematic Reviews"],"original-title":[],"language":"en","deposited":{"date-parts":[[2023,1,11]],"date-time":"2023-01-11T11:19:07Z","timestamp":1673435947000},"score":1,"resource":{"primary":{"URL":"http:\/\/doi.wiley.com\/10.1002\/14651858.CD004834.pub3"}},"subtitle":[],"editor":[{"name":"Cochrane Skin Group","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2020,8,27]]},"references-count":270,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2020,8]]}},"URL":"https:\/\/doi.org\/10.1002\/14651858.cd004834.pub3","relation":{},"ISSN":["1465-1858"],"issn-type":[{"value":"1465-1858","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,8,27]]}}}