{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,7]],"date-time":"2026-02-07T15:52:27Z","timestamp":1770479547199,"version":"3.49.0"},"update-to":[{"DOI":"10.1002\/14651858.cd004967","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2006,4,19]],"date-time":"2006-04-19T00:00:00Z","timestamp":1145404800000}}],"reference-count":43,"publisher":"Wiley","issue":"5","content-domain":{"domain":["wiley.com","cochranelibrary.com"],"crossmark-restriction":true},"short-container-title":[],"DOI":"10.1002\/14651858.cd004967.pub2","type":"journal-article","created":{"date-parts":[[2006,5,9]],"date-time":"2006-05-09T16:10:34Z","timestamp":1147191034000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Drugs for treating paracoccidioidomycosis"],"prefix":"10.1002","volume":"2019","author":[{"given":"Valfredo","family":"da Mota Menezes","sequence":"first","affiliation":[{"name":"Universidade Federal de Mato Grosso; Faculdade de Ci\u00eancias M\u00e9dicas; Av Fernando Correia da Costa S.N. Coxip\u00f3 Cuiab\u00e1 MT Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bernardo GO","family":"Soares","sequence":"additional","affiliation":[{"name":"Universidade Federal de S\u00e3o Paulo; Brazilian Cochrane Centre; Rua Pedro de Toledo 598 S\u00e3o Paulo SP Brazil 04039-001"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cor Jesus Fernandes","family":"Fontes","sequence":"additional","affiliation":[{"name":"Universidade Federal de Mato Grosso; Faculdade de Ci\u00eancias M\u00e9dicas UFMT Av Fernando Correia da Costa SN Cuiab\u00e1 MT Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,4,19]]},"reference":[{"issue":"11","key":"10.1002\/14651858.CD004967.pub2-BIB0001|cit1","doi-asserted-by":"crossref","first-page":"1462","DOI":"10.1086\/522973","article-title":"An open-label comparative pilot study of oral voriconazole and itraconazole for long-term treatment of paracoccidiodomycosis","volume":"45","author":"Queiroz-Telles","year":"2007","journal-title":"Clinical Infectious Diseases"},{"issue":"4","key":"10.1002\/14651858.CD004967.pub2-BIB0002|cit2","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1080\/mmy.40.4.411.417","article-title":"Randomized trial with itraconazole, ketoconazole and sulfadiazine in paracoccidioidomycosis","volume":"40","author":"Shikanai-Yasuda","year":"2002","journal-title":"Medical Mycology"},{"issue":"4","key":"10.1002\/14651858.CD004967.pub2-BIB0003|cit3","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1590\/S0036-46651986000400009","article-title":"Delayed results of treatment of paracoccidioidomycosis with amphotericin B plus sulfamides versus amphotericin B alone","volume":"28","author":"Dillon","year":"1986","journal-title":"Revista do Instituto de Medicina Tropical de S\u00e3o Paulo"},{"issue":"1","key":"10.1002\/14651858.CD004967.pub2-BIB0004|cit4","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1007\/BF00437128","article-title":"Paracoccidioidomycosis: A comparative study of the evolutionary serologic, clinical and radiologic results for patients treated with ketoconazole or amphotericinB plus sulfonamides","volume":"89","author":"Marques","year":"1985","journal-title":"Mycopathologia"},{"key":"10.1002\/14651858.CD004967.pub2-BIB0005|cit5","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1093\/jac\/49.suppl_1.21","article-title":"AmBisome: liposomal formulation, structure, mechanism of action and pre-clinical experience","volume":"49 Suppl 1","author":"Adler-Moore","year":"2002","journal-title":"Journal of Antimicrobial Chemotherapy"},{"issue":"2","key":"10.1002\/14651858.CD004967.pub2-BIB0006|cit6","first-page":"141","article-title":"New lipid formulations of amphotericin B. Review of the literature","volume":"22","author":"Andr\u00e9s","year":"2001","journal-title":"Revue de M\u00e9dicine Interne"},{"issue":"3","key":"10.1002\/14651858.CD004967.pub2-BIB0007|cit7","first-page":"147","article-title":"Mycosis: a therapeutic breviary","volume":"14","author":"Borelli","year":"1986","journal-title":"Medicina Cutanea Ibero-Latino-Americana"},{"issue":"2","key":"10.1002\/14651858.CD004967.pub2-BIB0008|cit8","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1128\/CMR.6.2.89","article-title":"Paracoccidioidomycosis: an update","volume":"6","author":"Brummer","year":"1993","journal-title":"Clinical Microbiology Reviews"},{"issue":"2","key":"10.1002\/14651858.CD004967.pub2-BIB0009|cit9","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1017\/S0950268801005052","article-title":"Paracoccidioidomycosis in Columbia: an ecological study","volume":"126","author":"Calle","year":"2001","journal-title":"Epidemiology and Infection"},{"issue":"5","key":"10.1002\/14651858.CD004967.pub2-BIB0010|cit10","doi-asserted-by":"crossref","first-page":"1441","DOI":"10.1590\/S0102-311X2002000500037","article-title":"Paracoccidioidomycosis mortality in Brazil (1980-1995)","volume":"18","author":"Coutinho","year":"2002","journal-title":"Cadernos de Saude Publica"},{"issue":"2","key":"10.1002\/14651858.CD004967.pub2-BIB0011|cit11","first-page":"82","article-title":"Treatment of paracoccidioidomycosis with ketoconazole","volume":"23","author":"Cuc\u00e9","year":"1981","journal-title":"Revista do Instituto de Medicina Tropical de S\u00e3o Paulo"},{"issue":"6","key":"10.1002\/14651858.CD004967.pub2-BIB0012|cit12","first-page":"231","article-title":"Treatment of paracoccidioidomycosis","volume":"20","author":"Negro","year":"1974","journal-title":"Revista da Associa\u00e7\u00e3o M\u00e9dica Brasileira"},{"issue":"1","key":"10.1002\/14651858.CD004967.pub2-BIB0013|cit13","first-page":"27","article-title":"Ketoconazole in paracoccidioidomycosis. A long-term therapy study with prolonged follow-up","volume":"24","author":"Negro","year":"1982","journal-title":"Revista do Instituto de Medicina Tropical de S\u00e3o Paulo"},{"issue":"4","key":"10.1002\/14651858.CD004967.pub2-BIB0014|cit14","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1590\/S0036-46651991000400006","article-title":"The sensitivity, specificity and efficiency values of some serological test used in the diagnosis of paracoccidioidomycosis","volume":"33","author":"Negro","year":"1991","journal-title":"Revista do Instituto de Medicina Tropical de S\u00e3o Paulo"},{"issue":"1","key":"10.1002\/14651858.CD004967.pub2-BIB0015|cit15","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1099\/0022-1317-49-1-37","article-title":"Evaluation of tests for antibody response in the follow-up of patients with acute and chronic forms of paracoccidioidomycosis","volume":"49","author":"Negro","year":"2000","journal-title":"Journal of Medical Microbiology"},{"issue":"1","key":"10.1002\/14651858.CD004967.pub2-BIB0016|cit16","first-page":"65","article-title":"Treatment of paracoccidioidomycosis: Retrospective study of 500 cases. Evaluation of therapeutic results with sulfonamides, amphotericin b, sulfamethoxazol plus trimethoprin, ketoconazole and miconazole","volume":"68","author":"Do Valle","year":"1993","journal-title":"Anais Brasileiro de Dermatologia"},{"issue":"2","key":"10.1002\/14651858.CD004967.pub2-BIB0017|cit17","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1590\/S0037-86821987000200012","article-title":"Paracoccidioidomycosis: a recently proposed classification of its clinical forms","volume":"20","author":"Franco","year":"1987","journal-title":"Revista da Sociedade Brasileira de Medicina Tropical"},{"issue":"5","key":"10.1002\/14651858.CD004967.pub2-BIB0018|cit18","doi-asserted-by":"crossref","first-page":"1275","DOI":"10.1093\/clinids\/21.5.1275","article-title":"Paracoccidioidomycosis and AIDS: an overview","volume":"21","author":"Goldani","year":"1995","journal-title":"Clinical Infectious Diseases"},{"key":"10.1002\/14651858.CD004967.pub2-BIB0019|cit19","unstructured":"Higgins JPT Green S Highly sensitive search strategies for identifying reports of randomized controlled trials in MEDLINE. Cochrane Handbook for Systematic Reviews of Interventions 4.2.5 updated May 2005; Appendix 5b www.cochrane.org\/resources\/handbook\/hbook.htm"},{"issue":"7303","key":"10.1002\/14651858.CD004967.pub2-BIB0020|cit20","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1136\/bmj.323.7303.42","article-title":"Systematic reviews in health care: Assessing the quality of controlled clinical trials","volume":"323","author":"J\u00fcni","year":"2001","journal-title":"BMJ"},{"issue":"1","key":"10.1002\/14651858.CD004967.pub2-BIB0021|cit21","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1007\/BF00436946","article-title":"Paracoccidioidomycosis in childhood: A critical review","volume":"82","author":"Londero","year":"1993","journal-title":"Mycopathologia"},{"issue":"2","key":"10.1002\/14651858.CD004967.pub2-BIB0022|cit22","first-page":"285","article-title":"Treatment of South American blastomycosis with sulfamide administered once per week. Follow-up of 2 to 3 years","volume":"70","author":"Lopes","year":"1966","journal-title":"O Hospital"},{"issue":"5","key":"10.1002\/14651858.CD004967.pub2-BIB0023|cit23","doi-asserted-by":"crossref","first-page":"1026","DOI":"10.1093\/clinids\/23.5.1026","article-title":"Paracoccidioidomycosis: case report and review","volume":"23","author":"Manns","year":"1996","journal-title":"Clinical Infectious Diseases"},{"issue":"4","key":"10.1002\/14651858.CD004967.pub2-BIB0024|cit24","first-page":"719","article-title":"Statistical aspects of the analysis of data from retrospective studies of disease","volume":"22","author":"Mantel","year":"1959","journal-title":"Journal of the National Cancer Institute"},{"issue":"2","key":"10.1002\/14651858.CD004967.pub2-BIB0025|cit25","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1590\/S0036-46651984000200008","article-title":"Evaluation of the treatment of paracoccidioidomycosis with ketoconazole","volume":"26","author":"Marcondes","year":"1984","journal-title":"Revista do Instituto de Medicina Tropical de S\u00e3o Paulo"},{"key":"10.1002\/14651858.CD004967.pub2-BIB0026|cit26","volume-title":"Paracoccidioidomycosis. Treatment with Itraconazole. Results achieved after long period follow-up [thesis]","author":"Marques","year":"1998"},{"issue":"2","key":"10.1002\/14651858.CD004967.pub2-BIB0027|cit27","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1093\/jac\/49.2.239","article-title":"New antifungal agents-treatment standards are beginning to grow old","volume":"49","author":"Maschmeyer","year":"2002","journal-title":"Journal of Antimicrobial Chemotherapy"},{"issue":"1","key":"10.1002\/14651858.CD004967.pub2-BIB0028|cit28","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1080\/02681219080000091","article-title":"Treatment of paracoccidioidomycosis with itraconazole","volume":"28","author":"Naranjo","year":"1990","journal-title":"Journal of Medical and Veterinary Mycology"},{"issue":"6","key":"10.1002\/14651858.CD004967.pub2-BIB0029|cit29","first-page":"453","article-title":"Prognostic value of the skin test in paracoccidiodomycosis","volume":"2","author":"Negroni","year":"1974","journal-title":"Medicina Cut\u00e1nea Ibero-Latino-Americana"},{"issue":"4","key":"10.1002\/14651858.CD004967.pub2-BIB0030|cit30","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1093\/clinids\/2.4.643","article-title":"Ketoconazole in the treatment of paracoccidioidomycosis and histoplasmosis","volume":"2","author":"Negroni","year":"1980","journal-title":"Reviews of Infectious Diseases"},{"key":"10.1002\/14651858.CD004967.pub2-BIB0031|cit31","first-page":"27","article-title":"Results of treatment with itraconazole by oral route in the paracoccidioidomycosis","volume":"Suppl","author":"Negroni","year":"1987","journal-title":"Revista Argentina de Micologia"},{"issue":"12","key":"10.1002\/14651858.CD004967.pub2-BIB0032|cit32","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1111\/j.1365-4362.1993.tb01396.x","article-title":"Paracoccidioidomycosis (south american blastomycosis, Lutz\u00b4s mycosis)","volume":"32","author":"Negroni","year":"1993","journal-title":"International Journal of Dermatology"},{"issue":"4","key":"10.1002\/14651858.CD004967.pub2-BIB0033|cit33","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1590\/S0037-86822003000400004","article-title":"Paracoccidioidomycosis: a clinical and epidemiological study of 422 cases observed in Mato Grosso do Sul","volume":"36","author":"Paniago","year":"2003","journal-title":"Revista da Sociedade Brasileira de Medicina Tropical"},{"issue":"3","key":"10.1002\/14651858.CD004967.pub2-BIB0034|cit34","first-page":"847","article-title":"Treatment of South American blastomycosis of pulmonary localization, with a sulfa administered in weekly doses","volume":"76","author":"Passos Filho","year":"1969","journal-title":"O Hospital"},{"issue":"3","key":"10.1002\/14651858.CD004967.pub2-BIB0035|cit35","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1590\/S0036-46652004000300002","article-title":"Paracoccidioidomycosis in children: clinical presentation, follow-up and outcome","volume":"46","author":"Pereira","year":"2004","journal-title":"Revista do Instituto de Medicina Tropical de S\u00e3o Paulo"},{"issue":"1B","key":"10.1002\/14651858.CD004967.pub2-BIB0036|cit36","first-page":"48","article-title":"Treatment of paracoccidioidomycosis with ketoconazole: a three-year experience","volume":"74","author":"Restrepo","year":"1983","journal-title":"American Journal of Medicine"},{"issue":"2","key":"10.1002\/14651858.CD004967.pub2-BIB0037|cit37","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1128\/iai.46.2.346-353.1984","article-title":"Estrogens inhibit mycelium-to-yeast transformation in the fungus Paracoccidioides brasiliensis: implications for resistance of females to paracoccidioidomycosis","volume":"46","author":"Restrepo","year":"1984","journal-title":"Infection and Immunity"},{"issue":"3 Pt 2","key":"10.1002\/14651858.CD004967.pub2-BIB0038|cit38","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/S0190-9622(08)81277-7","article-title":"Treatment of tropical mycoses","volume":"31","author":"Restrepo","year":"1994","journal-title":"Journal of the American Academy of Dermatology"},{"key":"10.1002\/14651858.CD004967.pub2-BIB0039|cit39","unstructured":"The Nordic Cochrane Centre, The Cochrane Collaboration Review Manager (RevMan) 2008"},{"issue":"1","key":"10.1002\/14651858.CD004967.pub2-BIB0040|cit40","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/S0891-5520(20)30577-8","article-title":"Fungal infection in Latin American countries","volume":"8","author":"Rios-Fabra","year":"1994","journal-title":"Infectious Disease Clinics North America"},{"key":"10.1002\/14651858.CD004967.pub2-BIB0041|cit41","first-page":"516","article-title":"Treatment of South American blastomycosis","volume":"6","author":"Sampaio","year":"1962","journal-title":"Jornal Brasileiro de Medicina"},{"issue":"5","key":"10.1002\/14651858.CD004967.pub2-BIB0042|cit42","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1001\/jama.1995.03520290060030","article-title":"Empirical evidence of bias. Dimensions of methodological quality associated with estimates of treatment effects in controlled trials","volume":"273","author":"Schulz","year":"1995","journal-title":"JAMA"},{"issue":"2","key":"10.1002\/14651858.CD004967.pub2-BIB0043|cit43","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1590\/S0036-46651987000200005","article-title":"Histopathology of cutaneous and mucosal lesions in human paracoccidioidomycosis","volume":"29","author":"Uribe","year":"1987","journal-title":"Revista do Instituto de Medicina Tropical de S\u00e3o Paulo"}],"container-title":["Cochrane Database of Systematic Reviews"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/onlinelibrary.wiley.com\/wol1\/doi\/10.1002\/14651858.CD004967.pub2\/fullpdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,6]],"date-time":"2026-02-06T20:02:06Z","timestamp":1770408126000},"score":1,"resource":{"primary":{"URL":"http:\/\/doi.wiley.com\/10.1002\/14651858.CD004967.pub2"}},"subtitle":[],"editor":[{"name":"Cochrane Infectious Diseases Group","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2006,4,19]]},"references-count":43,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2019,5]]}},"URL":"https:\/\/doi.org\/10.1002\/14651858.cd004967.pub2","relation":{},"ISSN":["1465-1858"],"issn-type":[{"value":"1465-1858","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,4,19]]}}}