{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,19]],"date-time":"2026-05-19T07:45:50Z","timestamp":1779176750668,"version":"3.51.4"},"update-to":[{"DOI":"10.1002\/14651858.cd005456","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2007,4,18]],"date-time":"2007-04-18T00:00:00Z","timestamp":1176854400000}}],"reference-count":98,"publisher":"Wiley","content-domain":{"domain":["wiley.com","cochranelibrary.com"],"crossmark-restriction":true},"short-container-title":[],"DOI":"10.1002\/14651858.cd005456.pub2","type":"journal-article","created":{"date-parts":[[2007,4,3]],"date-time":"2007-04-03T23:45:17Z","timestamp":1175643917000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":47,"title":["Prophylactic use of ergot alkaloids in the third stage of labour"],"prefix":"10.1002","author":[{"given":"Tippawan","family":"Liabsuetrakul","sequence":"first","affiliation":[{"name":"Prince of Songkla University; Epidemiology Unit, Faculty of Medicine; Hat Yai Songkhla Thailand 90110"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thanapan","family":"Choobun","sequence":"additional","affiliation":[{"name":"Prince of Songkla University; Department of Obstetrics and Gynecology, Faculty of Medicine; Hat Yai Songkhla Thailand 90110"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Krantarat","family":"Peeyananjarassri","sequence":"additional","affiliation":[{"name":"Prince of Songkla University; Department of Obstetrics and Gynecology, Faculty of Medicine; Hat Yai Songkhla Thailand 90110"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Q Monir","family":"Islam","sequence":"additional","affiliation":[{"name":"World Health Organization; Department of Family, Health and Research; Regional Office for South-East Asia World Health House, Indraprastha Estate Mahatma Gandhi Marg New Delhi India 110 002"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2007,4,18]]},"reference":[{"key":"10.1002\/14651858.CD005456.pub2-BIB0002|cit1","volume-title":"Comparative studies in the third stage of labour [MSc thesis]","author":"Begley","year":"1990"},{"key":"10.1002\/14651858.CD005456.pub2-BIB0001|cit2","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/S0266-6138(05)80091-9","article-title":"A comparison of 'active' and 'physiological' management of the third stage of labour","volume":"6","author":"Begley","year":"1990","journal-title":"Midwifery"},{"key":"10.1002\/14651858.CD005456.pub2-BIB0003|cit3","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/S0266-6138(05)80150-0","article-title":"The effect of ergometrine on breast feeding","volume":"6","author":"Begley","year":"1990","journal-title":"Midwifery"},{"issue":"3","key":"10.1002\/14651858.CD005456.pub2-BIB0004|cit4","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1111\/j.1471-0528.1951.tb04012.x","article-title":"The use of intramuscular ergometrine at the end of the second stage of normal labour","volume":"58","author":"Daley","year":"1951","journal-title":"Journal of Obstetrics and Gynaecology of the British Empire"},{"issue":"5","key":"10.1002\/14651858.CD005456.pub2-BIB0005|cit5","doi-asserted-by":"crossref","first-page":"464","DOI":"10.3109\/00016349609033355","article-title":"A placebo-controlled trial of oral ergometrine to reduce postpartum hemorrhage","volume":"75","author":"Groot","year":"1996","journal-title":"Acta Obstetricia et Gynecologica Scandinavica"},{"key":"10.1002\/14651858.CD005456.pub2-BIB0006|cit6","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1001\/jama.1964.03070060021004","article-title":"Oxytocic drugs in fourth stage of labor","volume":"189","author":"Howard","year":"1964","journal-title":"JAMA"},{"key":"10.1002\/14651858.CD005456.pub2-BIB0007|cit7","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/S0090-6980(79)80034-9","article-title":"The effect of prostaglandin F2alpha on third stage labour","volume":"18","author":"Kerekes","year":"1979","journal-title":"Prostaglandins"},{"key":"10.1002\/14651858.CD005456.pub2-BIB0008|cit8","first-page":"22","article-title":"A study of the vasopressor effects of oxytocics when used intravenously in the third stage of labour","volume":"64","author":"McGinty","year":"1956","journal-title":"Western Journal of Surgery"},{"key":"10.1002\/14651858.CD005456.pub2-BIB0009|cit9","doi-asserted-by":"crossref","first-page":"1066","DOI":"10.1111\/j.1471-0528.1999.tb08115.x","article-title":"Misoprostol compared with methylergometrine for the prevention of postpartum haemorrhage: a double-blind randomised trial","volume":"106","author":"Amant","year":"1999","journal-title":"British Journal of Obstetrics and Gynaecology"},{"key":"10.1002\/14651858.CD005456.pub2-BIB0010|cit10","unstructured":"Badhwar L Singh K Sethi N Gupta I Aggarwal N The value of nipple stimulation in the management of third stage of labour Proceedings of 13th World Congress of Gynaecology and Obstetrics (FIGO); 1991 September; Singapore 1991 16"},{"key":"10.1002\/14651858.CD005456.pub2-BIB0011|cit11","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1111\/j.1479-828X.1961.tb00551.x","article-title":"Clinical trial of SE505 - a new oxytocic mixture","volume":"1","author":"Barbaro","year":"1961","journal-title":"Australian and New Zealand Journal of Obstetrics and Gynaecology"},{"issue":"3","key":"10.1002\/14651858.CD005456.pub2-BIB0012|cit12","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/0028-2243(83)90098-9","article-title":"Uterine motility after post-partum application of sulprostone and other oxytocics","volume":"16","author":"Baumgarten","year":"1983","journal-title":"European Journal of Obstetrics & Gynecology and Reproductive Biology"},{"key":"10.1002\/14651858.CD005456.pub2-BIB0013|cit13","doi-asserted-by":"crossref","first-page":"1620","DOI":"10.1136\/bmj.2.5373.1620","article-title":"Intramuscular oxytocics and cord traction in third stage of labour","volume":"2","author":"Bonham","year":"1963","journal-title":"BMJ"},{"issue":"4","key":"10.1002\/14651858.CD005456.pub2-BIB0014|cit14","doi-asserted-by":"crossref","first-page":"1038","DOI":"10.1067\/mob.2002.126293","article-title":"Is rectal misoprostol really effective in the treatment of third stage of labor? A randomized controlled trial","volume":"187","author":"Caliskan","year":"2002","journal-title":"American Journal of Obstetrics and Gynecology"},{"issue":"4","key":"10.1002\/14651858.CD005456.pub2-BIB0015|cit15","first-page":"473","article-title":"Clinical trial of intramuscular OCM 505 and intravenous methergin in the third stage of labour","volume":"57","author":"Carp\u00e9n","year":"1968","journal-title":"Annales Chirurgiae et Gynaecologiae Fenniae"},{"key":"10.1002\/14651858.CD005456.pub2-BIB0016|cit16","doi-asserted-by":"crossref","unstructured":"Chatterjee A Misoprostol and the 3rd stage XVI FIGO World Congress of Obstetrics & Gynecology (Book 4); 2000 Sept 3-8; Washington DC, USA 2000 29","DOI":"10.1016\/S0020-7292(00)82594-1"},{"issue":"5342","key":"10.1002\/14651858.CD005456.pub2-BIB0017|cit17","doi-asserted-by":"crossref","first-page":"1390","DOI":"10.1136\/bmj.1.5342.1390","article-title":"Use of \"syntometrine\" in the third stage of labour","volume":"1","author":"Chukudebelu","year":"1963","journal-title":"BMJ"},{"issue":"5","key":"10.1002\/14651858.CD005456.pub2-BIB0018|cit18","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1111\/j.1447-0756.1999.tb01171.x","article-title":"The use of rectal misoprostol as active pharmacological management of the third stage of labor","volume":"25","author":"Diab","year":"1999","journal-title":"Journal of Obstetrics & Gynaecology Research"},{"key":"10.1002\/14651858.CD005456.pub2-BIB0019|cit19","first-page":"60","article-title":"Choice of an oxytocic agent for routine use at delivery","volume":"2","author":"Docherty","year":"1981","journal-title":"Journal of Obstetrics and Gynaecology"},{"issue":"3-4","key":"10.1002\/14651858.CD005456.pub2-BIB0020|cit20","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1155\/S1064744900000193","article-title":"Use of methergine for the prevention of postoperative endometritis in non-elective cesarean section patients","volume":"8","author":"Dweck","year":"2000","journal-title":"Infectious Diseases in Obstetrics & Gynecology"},{"key":"10.1002\/14651858.CD005456.pub2-BIB0021|cit21","doi-asserted-by":"crossref","first-page":"155","DOI":"10.5694\/j.1326-5377.1957.tb57778.x","article-title":"A comparative study of ergometrine and 'methergin' used in the management of the third stage of labour","volume":"2","author":"Forster","year":"1957","journal-title":"Medical Journal of Australia"},{"key":"10.1002\/14651858.CD005456.pub2-BIB0022|cit22","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1111\/j.1479-828X.1965.tb00289.x","article-title":"Clinical trial of an oxytocin-ergometrine mixture (first of two trials)","volume":"5","author":"Francis","year":"1965","journal-title":"Australian and New Zealand Journal of Obstetrics and Gynaecology"},{"key":"10.1002\/14651858.CD005456.pub2-BIB0023|cit23","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1111\/j.1479-828X.1965.tb00289.x","article-title":"Clinical trial of an oxytocin-ergometrine mixture (second of two trials)","volume":"5","author":"Francis","year":"1965","journal-title":"Australian and New Zealand Journal of Obstetrics and Gynaecology"},{"issue":"6","key":"10.1002\/14651858.CD005456.pub2-BIB0024|cit24","doi-asserted-by":"crossref","first-page":"1306","DOI":"10.1016\/0002-9378(57)90274-0","article-title":"Comparative clinical evaluation of postpartum oxytocics","volume":"73","author":"Friedman","year":"1957","journal-title":"American Journal of Obstetrics and Gynecology"},{"issue":"1","key":"10.1002\/14651858.CD005456.pub2-BIB0025|cit25","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/S0002-9378(16)36877-6","article-title":"A comparison of oxytocic drugs in the management of the placental stage","volume":"76","author":"Fugo","year":"1958","journal-title":"American Journal of Obstetrics and Gynecology"},{"key":"10.1002\/14651858.CD005456.pub2-BIB0026|cit26","first-page":"85","article-title":"Methergine and ergonovine in the third stage of labor","volume":"15","author":"Groeber","year":"1960","journal-title":"Obstetrics & Gynecology"},{"issue":"8","key":"10.1002\/14651858.CD005456.pub2-BIB0027|cit27","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1111\/j.1471-0528.1979.tb10825.x","article-title":"Blood pressure changes when uterine stimulants are used after normal delivery","volume":"86","author":"Hacker","year":"1979","journal-title":"British Journal of Obstetrics and Gynaecology"},{"issue":"1 Pt 2","key":"10.1002\/14651858.CD005456.pub2-BIB0028|cit28","first-page":"S130","article-title":"A randomized, double-blinded, placebo controlled trial of oxytocin at the beginning versus the end of the third stage of labor for prevention of postpartum hemorrhage","volume":"182","author":"Huh","year":"2000","journal-title":"American Journal of Obstetrics and Gynecology"},{"issue":"3","key":"10.1002\/14651858.CD005456.pub2-BIB0029|cit29","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1159\/000293371","article-title":"Effect of oxytocics on prostaglandin levels in the third stage of labour","volume":"29","author":"Ilancheran","year":"1990","journal-title":"Gynecologic and Obstetric Investigation"},{"issue":"9","key":"10.1002\/14651858.CD005456.pub2-BIB0030|cit30","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1080\/14767050701500406","article-title":"Effect of oxytocics on the blood pressure of normotensive Nigerian parturients","volume":"20","author":"Jago","year":"2007","journal-title":"The Journal of Maternal-Fetal and Neonatal Medicine"},{"issue":"1","key":"10.1002\/14651858.CD005456.pub2-BIB0031|cit31","first-page":"129","article-title":"Effect of ergot alkaloid derivatives on milk secretion in the immediate postpartum period","volume":"7","author":"Jolivet","year":"1978","journal-title":"Journal de Gynecologie, Obstetrique et Biologie de la Reproduction"},{"issue":"5342","key":"10.1002\/14651858.CD005456.pub2-BIB0032|cit32","doi-asserted-by":"crossref","first-page":"1391","DOI":"10.1136\/bmj.1.5342.1391","article-title":"Clinical trial of \"syntometrine\" in the third stage of labour","volume":"1","author":"Kemp","year":"1963","journal-title":"British Medical Journal"},{"key":"10.1002\/14651858.CD005456.pub2-BIB0033|cit33","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/0028-2243(95)80014-J","article-title":"Abu Dhabi third stage trial: oxytocin vs syntometrine in the active management of the third stage of labour","volume":"58","author":"Khan","year":"1995","journal-title":"European Journal of Obstetrics & Gynecology and Reproductive Biology"},{"issue":"3","key":"10.1002\/14651858.CD005456.pub2-BIB0034|cit34","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1046\/j.1341-8076.2003.00097.x","article-title":"Effects of methylergometrine and oxytocin on thoracic epidural pressure during cesarean section","volume":"29","author":"Kikutani","year":"2003","journal-title":"Journal of Obstetrics and Gynaecology Research"},{"issue":"7","key":"10.1002\/14651858.CD005456.pub2-BIB0035|cit35","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1111\/j.0001-6349.2004.00572.x","article-title":"A pilot-randomized comparison of sublingual misoprostol with syntometrine on the blood loss in third stage of labor","volume":"83","author":"Lam","year":"2004","journal-title":"Acta Obstetricia et Gynecologica Scandinavica"},{"issue":"3","key":"10.1002\/14651858.CD005456.pub2-BIB0036|cit36","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/S0090-6980(01)00154-X","article-title":"A prospective randomised trial to compare the efficacy and safety of hemabate and syntometrine for the prevention of primary postpartum haemorrhage","volume":"66","author":"Lamont","year":"2001","journal-title":"Prostaglandins & Other Lipid Mediators"},{"key":"10.1002\/14651858.CD005456.pub2-BIB0037|cit37","first-page":"Doc 83","article-title":"The Salford third stage trial: oxytocin plus ergometrine vs oxytocin alone in the active management of the third stage of labor","volume":"2","author":"Mitchell","year":"1993","journal-title":"Online Journal of Current Clinical Trials"},{"key":"10.1002\/14651858.CD005456.pub2-BIB0038|cit38","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1093\/bja\/51.2.113","article-title":"Ergometrine or oxytocin? Blood loss and side-effects at spontaneous vertex delivery","volume":"51","author":"Moir","year":"1979","journal-title":"British Journal of Anaesthesia"},{"key":"10.1002\/14651858.CD005456.pub2-BIB0039|cit39","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1093\/bja\/48.6.571","article-title":"Ergometrine, oxytocin and extradural analgesia","volume":"48","author":"Moodie","year":"1976","journal-title":"British Journal of Anaesthesia"},{"issue":"4","key":"10.1002\/14651858.CD005456.pub2-BIB0040|cit40","doi-asserted-by":"crossref","first-page":"908","DOI":"10.1016\/0002-9378(56)90591-9","article-title":"Is methylergonovine tartrate superior to ergonovine maleate","volume":"71","author":"Moore","year":"1956","journal-title":"American Journal of Obstetrics and Gynecology"},{"key":"10.1002\/14651858.CD005456.pub2-BIB0041|cit41","first-page":"424","article-title":"A comparative study of different medical treatments of the third stage of labour","volume":"53","author":"Nieminen","year":"1964","journal-title":"Annales Chirurgiae et Gynaecologiae Fenniae"},{"issue":"2","key":"10.1002\/14651858.CD005456.pub2-BIB0042|cit42","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/j.ijgo.2007.11.009","article-title":"A randomized comparative study of prophylactic oxytocin versus ergometrine in the third stage of labor","volume":"101","author":"Orji","year":"2008","journal-title":"International Journal of Gynecology & Obstetrics"},{"key":"10.1002\/14651858.CD005456.pub2-BIB0043|cit43","doi-asserted-by":"crossref","first-page":"178","DOI":"10.5694\/j.1326-5377.1977.tb130601.x","article-title":"Ergometrine and third stage blood loss","volume":"1","author":"Paull","year":"1977","journal-title":"Medical Journal of Australia"},{"issue":"7","key":"10.1002\/14651858.CD005456.pub2-BIB0044|cit44","first-page":"384","article-title":"Study of the effects of using uterine stimulants on milk secretion during delivery","volume":"31","author":"Pei","year":"1996","journal-title":"Zhonghua Hu Li Za Zhi [Chinese Journal of Nursing]"},{"issue":"1","key":"10.1002\/14651858.CD005456.pub2-BIB0045|cit45","doi-asserted-by":"crossref","first-page":"87","DOI":"10.18597\/rcog.655","article-title":"Active management of childbirth with sublingual misoprostol: a controlled clinical trial in the Hospital de Maternidad Rafael Calvo","volume":"53","author":"Penaranda","year":"2002","journal-title":"Revista Colombiana de Obstetricia y Ginecologia"},{"key":"10.1002\/14651858.CD005456.pub2-BIB0046|cit46","doi-asserted-by":"crossref","unstructured":"Rajwani J Survana K Active management of third stage of labor - a comparative study [abstract] XVI FIGO World Congress of Obstetrics & Gynecology (Book 3); 2000 Sept 3-8; Washington DC, USA 2000 54","DOI":"10.1016\/S0020-7292(00)81610-0"},{"key":"10.1002\/14651858.CD005456.pub2-BIB0047|cit47","first-page":"642","article-title":"Role of intramyometrial prostaglandin E2 in management of third stage of labour","volume":"77","author":"Ramesh","year":"1983","journal-title":"Indian Journal of Medical Research"},{"issue":"2","key":"10.1002\/14651858.CD005456.pub2-BIB0048|cit48","first-page":"44","article-title":"Active management of third stage of labour. A comparative study in high risk patients for atonic postpartum haemorrhage","volume":"51","author":"Reddy","year":"2001","journal-title":"Journal of Obstetrics and Gynecology of India"},{"issue":"3","key":"10.1002\/14651858.CD005456.pub2-BIB0049|cit49","first-page":"99","article-title":"Is routine administration of syntometrine still justified in the management of the third stage of labour?","volume":"43","author":"Rooney","year":"1985","journal-title":"Health Bulletin"},{"issue":"3","key":"10.1002\/14651858.CD005456.pub2-BIB0050|cit50","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1111\/j.1447-0756.2007.00520.x","article-title":"Prospective study of intramuscular ergometrine compared with intramuscular oxytocin for prevention of postpartum hemorrhage","volume":"33","author":"Saito","year":"2007","journal-title":"Journal of Obstetrics and Gynaecology Research"},{"issue":"2","key":"10.1002\/14651858.CD005456.pub2-BIB0051|cit51","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1016\/j.ijgo.2009.06.007","article-title":"Comparison of sublingual misoprostol, intravenous oxytocin, and intravenous methylergometrine in active management of the third stage of labor","volume":"107","author":"Singh","year":"2009","journal-title":"International Journal of Gynecology & Obstetrics"},{"key":"10.1002\/14651858.CD005456.pub2-BIB0052|cit52","first-page":"173","article-title":"Clinical experience with simultaneous intramuscular injection of oxytocin and methylergometrine","volume":"53","author":"Soiva","year":"1964","journal-title":"Annales Chirurgiae et Gynaecologiae Fenniae"},{"issue":"6","key":"10.1002\/14651858.CD005456.pub2-BIB0053|cit53","first-page":"694","article-title":"Active pharmacologic management of the third stage of labor. A comparison of oxytocin and ergometrine","volume":"52","author":"Sorbe","year":"1978","journal-title":"Obstetrics & Gynecology"},{"key":"10.1002\/14651858.CD005456.pub2-BIB0054|cit54","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1111\/j.1471-0528.1963.tb04955.x","article-title":"Syntometrine in the management of the third stage of labour","volume":"70","author":"Stearn","year":"1963","journal-title":"Journal of Obstetrics and Gynaecology of the British Commonwealth"},{"key":"10.1002\/14651858.CD005456.pub2-BIB0055|cit55","doi-asserted-by":"crossref","first-page":"36","DOI":"10.3109\/01443618409075741","article-title":"A study on the effect of ergometrine on serum prolactin levels following delivery","volume":"5","author":"Symes","year":"1984","journal-title":"Journal of Obstetrics and Gynaecology"},{"issue":"2","key":"10.1002\/14651858.CD005456.pub2-BIB0056|cit56","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1111\/j.1471-0528.1970.tb03489.x","article-title":"A management of the third stage to reduce feto-maternal transfusion","volume":"77","author":"Terry","year":"1970","journal-title":"Journal of Obstetrics and Gynaecology of the British Commonwealth"},{"issue":"1","key":"10.1002\/14651858.CD005456.pub2-BIB0057|cit57","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/0028-2243(93)90048-H","article-title":"Management of the third stage of labour in women at low risk of postpartum haemorrhage","volume":"48","author":"Thilaganathan","year":"1993","journal-title":"European Journal of Obstetrics & Gynecology and Reproductive Biology"},{"issue":"6642","key":"10.1002\/14651858.CD005456.pub2-BIB0058|cit58","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1136\/bmj.297.6642.167","article-title":"Plasma oxytocin during third stage of labour: comparison of natural and active management","volume":"297","author":"Thornton","year":"1988","journal-title":"BMJ"},{"issue":"17","key":"10.1002\/14651858.CD005456.pub2-BIB0059|cit59","doi-asserted-by":"crossref","first-page":"2P","DOI":"10.1042\/cs073002Pa","article-title":"Plasma oxytocin in the third stage of human labour with and without syntometrine \u00a0[abstract]","volume":"73 Suppl","author":"Thornton","year":"1987","journal-title":"Clinical Science"},{"issue":"8","key":"10.1002\/14651858.CD005456.pub2-BIB0060|cit60","doi-asserted-by":"crossref","first-page":"596","DOI":"10.1111\/j.1471-0528.1974.tb00523.x","article-title":"A comparison of central venous pressure changes in the third stage of labour following oxytocic drugs and diazepam","volume":"81","author":"Vaughan Williams","year":"1974","journal-title":"Journal of Obstetrics and Gynaecology of the British Commonwealth"},{"issue":"1","key":"10.1002\/14651858.CD005456.pub2-BIB0061|cit61","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.ijgo.2004.05.016","article-title":"Sublingual misoprostol versus methylergometrine for active management of third stage of labor","volume":"87","author":"Vimala","year":"2004","journal-title":"International Journal of Gynecology & Obstetrics"},{"issue":"2","key":"10.1002\/14651858.CD005456.pub2-BIB0062|cit62","first-page":"209","article-title":"Effect of methylergonovine on puerperal prolactin secretion","volume":"46","author":"Weiss","year":"1975","journal-title":"Obstetrics & Gynecology"},{"issue":"25","key":"10.1002\/14651858.CD005456.pub2-BIB0063|cit63","first-page":"1223","article-title":"Active direction of the postpartum period with Syntometrin","volume":"43","author":"Yardim","year":"1967","journal-title":"Der Landarzt"},{"issue":"5","key":"10.1002\/14651858.CD005456.pub2-BIB0064|cit64","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1111\/j.1471-0528.1995.tb11288.x","article-title":"A randomised double blind comparison of syntometrine and syntocinon in the management of the third stage of labour","volume":"102","author":"Yuen","year":"1995","journal-title":"British Journal of Obstetrics and Gynaecology"},{"issue":"9764","key":"10.1002\/14651858.CD005456.pub2-BIB0065|cit65","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1016\/S0140-6736(10)62049-1","article-title":"Maternal, neonatal, and child health in southeast Asia: towards greater regional collaboration","volume":"377","author":"Acuin","year":"2011","journal-title":"Lancet"},{"issue":"1","key":"10.1002\/14651858.CD005456.pub2-BIB0066|cit66","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1080\/00016349808565812","article-title":"Methylergometrine during the early puerperium; a prospective randomized double blind study","volume":"77","author":"Andersen","year":"1998","journal-title":"Acta Obstetricia et Gynecologica Scandinavica"},{"issue":"7","key":"10.1002\/14651858.CD005456.pub2-BIB0067|cit67","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD007412","article-title":"Active versus expectant management for women in the third stage of labour","author":"Begley","year":"2010","journal-title":"Cochrane Database of Systematic Reviews"},{"issue":"3","key":"10.1002\/14651858.CD005456.pub2-BIB0068|cit68","first-page":"128","article-title":"Methylergonovine maleate: a proposal for its more specific use","volume":"7","author":"Borri","year":"1986","journal-title":"Biological Research in Pregnancy and Perinatology"},{"issue":"6","key":"10.1002\/14651858.CD005456.pub2-BIB0069|cit69","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1016\/S1526-9523(01)00192-1","article-title":"Management of the third stage of labor: an evidence-based approach","volume":"46","author":"Brucker","year":"2001","journal-title":"Journal of Midwifery and Womens Health"},{"issue":"4","key":"10.1002\/14651858.CD005456.pub2-BIB0070|cit70","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD001808","article-title":"Prophylactic oxytocin for the third stage of labour","author":"Cotter","year":"2001","journal-title":"Cochrane Database of Systematic Reviews"},{"issue":"3","key":"10.1002\/14651858.CD005456.pub2-BIB0071|cit71","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1016\/S0950-3552(05)80385-2","article-title":"Prevention of postpartum haemorrhage","volume":"9","author":"Groot","year":"1995","journal-title":"Bailliere\u2019s Clinical Obstetrics and Gynaecology"},{"issue":"1","key":"10.1002\/14651858.CD005456.pub2-BIB0072|cit72","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/0301-2115(95)02531-6","article-title":"The role of oral (methyl)ergometrine in the prevention of postpartum haemorrhage","volume":"69","author":"Groot","year":"1996","journal-title":"European Journal of Obstetrics & Gynecology and Reproductive Biology"},{"issue":"4","key":"10.1002\/14651858.CD005456.pub2-BIB0073|cit73","first-page":"523","article-title":"Ergot alkaloids. Current status and review of clinical pharmacology and therapeutic use compared with other oxytocics in obstetrics and gynaecology","volume":"56","author":"Groot","year":"1998","journal-title":"Drugs"},{"issue":"1","key":"10.1002\/14651858.CD005456.pub2-BIB0074|cit74","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/S0301-2115(00)00311-0","article-title":"History and use of oxytocics","volume":"94","author":"Hertog","year":"2001","journal-title":"European Journal of Obstetrics & Gynecology and Reproductive Biology"},{"issue":"1","key":"10.1002\/14651858.CD005456.pub2-BIB0075|cit75","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1111\/j.1471-0528.1994.tb13015.x","article-title":"Postpartum eclampsia associated with ergometrine maleate administration","volume":"101","author":"Dua","year":"1994","journal-title":"British Journal of Obstetrics and Gynaecology"},{"key":"10.1002\/14651858.CD005456.pub2-BIB0076|cit76","doi-asserted-by":"crossref","first-page":"F152","DOI":"10.1136\/fn.87.2.F152","article-title":"John Chassar Moir (1900-1977) and the discovery of ergometrine","volume":"87","author":"Dunn","year":"2002","journal-title":"Archives of Diseases in Childhood. Fetal & Neonatal Edition"},{"issue":"7109","key":"10.1002\/14651858.CD005456.pub2-BIB0077|cit77","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1136\/bmj.315.7109.629","article-title":"Bias in meta-analysis detected by a simple, graphical test","volume":"315","author":"Egger","year":"1997","journal-title":"BMJ"},{"issue":"2","key":"10.1002\/14651858.CD005456.pub2-BIB0078|cit78","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/S0020-7292(02)00412-5","article-title":"Postpartum second degree heart block induced by methergine","volume":"81","author":"Gowri","year":"2003","journal-title":"International Journal of Gynecology & Obstetrics"},{"issue":"3","key":"10.1002\/14651858.CD005456.pub2-BIB0079|cit79","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD000494.pub3","article-title":"Prostaglandins for preventing postpartum haemorrhage","author":"G\u00fclmezoglu","year":"2007","journal-title":"Cochrane Database of Systematic Reviews"},{"issue":"20","key":"10.1002\/14651858.CD005456.pub2-BIB0080|cit80","doi-asserted-by":"crossref","first-page":"3443","DOI":"10.1002\/sim.2380","article-title":"A modified test for small-study effects in meta-analyses of controlled trials with binary endpoints","volume":"25","author":"Harbord","year":"2006","journal-title":"Statistics in Medicine"},{"key":"10.1002\/14651858.CD005456.pub2-BIB0081|cit81","unstructured":"Higgins JPT Green S Cochrane Handbook for Systematic Reviews of Interventions 4.2.5 [updated May 2005] In: The Cochrane Library, Issue 3, 2005. Chichester, UK: John Wiley & Sons, Ltd"},{"key":"10.1002\/14651858.CD005456.pub2-BIB0082|cit82","unstructured":"Higgins JPT Green S Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 [updated March 2011]. The Cochrane Collaboration, 2011 Available from www.cochrane-handbook.org"},{"issue":"9726","key":"10.1002\/14651858.CD005456.pub2-BIB0083|cit83","doi-asserted-by":"crossref","first-page":"1609","DOI":"10.1016\/S0140-6736(10)60518-1","article-title":"Maternal mortality for 181 countries, 1980?2008: a systematic analysis of progress towards Millennium Development Goal","volume":"375","author":"Hogan","year":"2010","journal-title":"Lancet\u00a0"},{"issue":"1","key":"10.1002\/14651858.CD005456.pub2-BIB0084|cit84","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/0301-2115(95)02530-8","article-title":"Instability of (methyl)ergometrine in tropical climates: an overview","volume":"69","author":"Hogerzeil","year":"1996","journal-title":"European Journal of Obstetrics & Gynecology and Reproductive Biology"},{"issue":"3","key":"10.1002\/14651858.CD005456.pub2-BIB0085|cit85","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/S0020-7292(02)00020-6","article-title":"Preventing postpartum hemorrhage in low-resource settings","volume":"77","author":"McCormick","year":"2002","journal-title":"International Journal of Gynecology & Obstetrics"},{"issue":"1","key":"10.1002\/14651858.CD005456.pub2-BIB0086|cit86","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD000201.pub2","article-title":"Prophylactic ergometrine-oxytocin versus oxytocin for the third stage of labour","author":"McDonald","year":"2004","journal-title":"Cochrane Database of Systematic Reviews"},{"issue":"9263","key":"10.1002\/14651858.CD005456.pub2-BIB0087|cit87","doi-asserted-by":"crossref","first-page":"1191","DOI":"10.1016\/S0140-6736(00)04337-3","article-title":"The CONSORT statement: revised recommendations for improving the quality of reports of parallel-group randomised trials","volume":"357","author":"Moher","year":"2001","journal-title":"Lancet"},{"issue":"3","key":"10.1002\/14651858.CD005456.pub2-BIB0088|cit88","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD000007","article-title":"Active versus expectant management in the third stage of labour","author":"Prendiville","year":"2000","journal-title":"Cochrane Database of Systematic Reviews"},{"key":"10.1002\/14651858.CD005456.pub2-BIB0089|cit89","unstructured":"The Cochrane Collaboration Review Manager (RevMan) 2003"},{"key":"10.1002\/14651858.CD005456.pub2-BIB0090|cit90","unstructured":"The Nordic Cochrane Centre, The Cochrane Collaboration Review Manager (RevMan) 2011"},{"issue":"9","key":"10.1002\/14651858.CD005456.pub2-BIB0091|cit91","first-page":"805","article-title":"The etiology of maternal mortality in developing countries: what do verbal autopsies tell us?","volume":"79","author":"Sloan","year":"2001","journal-title":"Bulletin of the World Health Organization"},{"issue":"4","key":"10.1002\/14651858.CD005456.pub2-BIB0092|cit92","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1016\/S0091-2182(97)60134-2","article-title":"Mechanisms of drugs that affect uterine motility","volume":"42","author":"Sultatos","year":"1997","journal-title":"Journal of Nurse-Midwifery"},{"issue":"6","key":"10.1002\/14651858.CD005456.pub2-BIB0093|cit93","first-page":"821","article-title":"Ergonovine-induced coronary artery spasm and myocardial infarction after normal delivery","volume":"66","author":"Taylor","year":"1985","journal-title":"Obstetrics & Gynecology"},{"issue":"2","key":"10.1002\/14651858.CD005456.pub2-BIB0094|cit94","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/0028-2243(95)02104-Z","article-title":"History of ergot alkaloids from ergotism to ergometrine","volume":"60","author":"Dongen","year":"1995","journal-title":"European Journal of Obstetrics & Gynecology and Reproductive Biology"},{"issue":"4","key":"10.1002\/14651858.CD005456.pub2-BIB0095|cit95","doi-asserted-by":"crossref","first-page":"270","DOI":"10.3109\/00016349509024448","article-title":"Preventing the recurrence of atonic postpartum hemorrhage: a double-blind trial","volume":"74","author":"Selm","year":"1995","journal-title":"Acta Obstetricia et Gynecologica Scandinavica"},{"key":"10.1002\/14651858.CD005456.pub2-BIB0096|cit96","volume-title":"Managing complications in pregnancy and childbirth: a guide for midwives and doctors","author":"World Health Organization","year":"2000"},{"key":"10.1002\/14651858.CD005456.pub2-BIB0097|cit97","volume-title":"Maternal mortality in 1995: estimates developed by WHO, UNICEF, UNFPA","author":"World Health Organization","year":"2001"},{"key":"10.1002\/14651858.CD005456.pub2-BIB0098|cit98","volume-title":"Pregnancy, childbirth, postpartum and newborn care: a guide for essential practice","author":"World Health Organization","year":"2003"}],"updated-by":[{"DOI":"10.1002\/14651858.cd005456.pub3","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2018,6,7]],"date-time":"2018-06-07T00:00:00Z","timestamp":1528329600000}}],"container-title":["Cochrane Database of Systematic Reviews"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full\/10.1002\/14651858.CD005456.pub2","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,11]],"date-time":"2023-05-11T09:20:40Z","timestamp":1683796840000},"score":1,"resource":{"primary":{"URL":"https:\/\/doi.wiley.com\/10.1002\/14651858.CD005456.pub2"}},"subtitle":[],"editor":[{"name":"Cochrane Pregnancy and Childbirth Group","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2007,4,18]]},"references-count":98,"URL":"https:\/\/doi.org\/10.1002\/14651858.cd005456.pub2","relation":{"new_version":[{"id-type":"doi","id":"10.1002\/14651858.CD005456.pub3","asserted-by":"object"}]},"ISSN":["1465-1858"],"issn-type":[{"value":"1465-1858","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,4,18]]}}}