{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,2]],"date-time":"2026-04-02T22:41:25Z","timestamp":1775169685550,"version":"3.50.1"},"update-to":[{"DOI":"10.1002\/14651858.cd006843","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2008,10,8]],"date-time":"2008-10-08T00:00:00Z","timestamp":1223424000000}}],"reference-count":27,"publisher":"Wiley","content-domain":{"domain":["wiley.com","cochranelibrary.com"],"crossmark-restriction":true},"short-container-title":[],"DOI":"10.1002\/14651858.cd006843.pub2","type":"journal-article","created":{"date-parts":[[2008,10,9]],"date-time":"2008-10-09T01:07:07Z","timestamp":1223514427000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":45,"title":["Fetal fibronectin testing for reducing the risk of preterm birth"],"prefix":"10.1002","author":[{"given":"Vincenzo","family":"Berghella","sequence":"first","affiliation":[{"name":"Thomas Jefferson University; Director, Division of Maternal Fetal Medicine; 834 Chestnut Street, Suite 400 Philadelphia USA PA 19107"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edward","family":"Hayes","sequence":"additional","affiliation":[{"name":"Thomas Jefferson University; Department of Obstetrics and Gynecology; 834 Chestnut Street, Suite 400 Philadelphia USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John","family":"Visintine","sequence":"additional","affiliation":[{"name":"Thomas Jefferson University; Department of Obstetrics and Gynecology; 834 Chestnut Street, Suite 400 Philadelphia USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jason K","family":"Baxter","sequence":"additional","affiliation":[{"name":"Thomas Jefferson University; Department of Obstetrics and Gynecology; 834 Chestnut Street, Suite 400 Philadelphia USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2008,10,8]]},"reference":[{"issue":"6 Pt 2","key":"10.1002\/14651858.CD006843.pub2-BIB0001|cit1","first-page":"S80","article-title":"Does fetal fibronectin use in the diagnosis of preterm labor affect physician behavior and health care costs [abstract]","volume":"187","author":"Grobman","year":"2002","journal-title":"American Journal of Obstetrics and Gynecology"},{"key":"10.1002\/14651858.CD006843.pub2-BIB0002|cit2","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/j.ajog.2003.11.034","article-title":"Does fetal fibronectin use in the diagnosis of preterm labor affect physician behavior and health care costs? A randomized trial","volume":"191","author":"Grobman","year":"2004","journal-title":"American Journal of Obstetrics and Gynecology"},{"issue":"6 Suppl","key":"10.1002\/14651858.CD006843.pub2-BIB0003|cit3","doi-asserted-by":"crossref","first-page":"S136","DOI":"10.1016\/S0002-9378(01)80232-5","article-title":"Effect of the fetal fibronectin assay on preterm labor management [abstract]","volume":"185","author":"Hansen","year":"2001","journal-title":"American Journal of Obstetrics and Gynecology"},{"key":"10.1002\/14651858.CD006843.pub2-BIB0004|cit4","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1016\/j.ajog.2003.08.041","article-title":"Prospective randomized trial of fetal fibronectin on preterm labor management in a tertiary care center","volume":"190","author":"Lowe","year":"2004","journal-title":"American Journal of Obstetrics and Gynecology"},{"issue":"4","key":"10.1002\/14651858.CD006843.pub2-BIB0005|cit5","doi-asserted-by":"crossref","first-page":"426.el","DOI":"10.1016\/j.ajog.2007.07.017","article-title":"Does knowledge of cervical length and fetal fibronectin affect management of women with preterm labor? A randomized trial","volume":"197","author":"Ness","year":"2007","journal-title":"American Journal of Obstetrics and Gynecology"},{"issue":"6 Suppl 1","key":"10.1002\/14651858.CD006843.pub2-BIB0006|cit6","doi-asserted-by":"crossref","first-page":"S67","DOI":"10.1016\/j.ajog.2006.10.210","article-title":"Use of fetal fibronectin and transvaginal ultrasound cervical length to triage women with suspected preterm labor: a randomized trial","volume":"195","author":"Ness","year":"2006","journal-title":"American Journal of Obstetrics and Gynecology"},{"issue":"4 Suppl","key":"10.1002\/14651858.CD006843.pub2-BIB0007|cit7","first-page":"97S","article-title":"The cost-effectiveness of fetal fibronectin testing in suspected preterm labor: a randomized trial","volume":"99","author":"Nguyen","year":"2002","journal-title":"Obstetrics & Gynecology"},{"key":"10.1002\/14651858.CD006843.pub2-BIB0008|cit8","doi-asserted-by":"crossref","first-page":"1588","DOI":"10.1067\/mob.2003.390","article-title":"Fetal fibronectin: the impact of a rapid test on the treatment of women with preterm labor symptoms","volume":"188","author":"Plaut","year":"2003","journal-title":"American Journal of Obstetrics and Gynecology"},{"issue":"5 Pt 1","key":"10.1002\/14651858.CD006843.pub2-BIB0009|cit9","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1097\/00006250-200305000-00005","article-title":"Randomized clinical trial of metronidazole plus erythromycin to prevent spontaneous preterm delivery in fetal fibronectin-positive women","volume":"101","author":"Andrews","year":"2003","journal-title":"Obstetrics & Gynecology"},{"issue":"3","key":"10.1002\/14651858.CD006843.pub2-BIB0010|cit10","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1016\/j.ajog.2004.02.019","article-title":"The randomized nitric oxide tocolysis trial (RNOTT) for the treatment of preterm labor","volume":"19","author":"Bisits","year":"2004","journal-title":"American Journal of Obstetrics and Gynecology"},{"issue":"10","key":"10.1002\/14651858.CD006843.pub2-BIB0011|cit11","doi-asserted-by":"crossref","first-page":"626","DOI":"10.1038\/sj.jp.7211359","article-title":"A randomized multicenter study to determine the efficacy of activity restriction for preterm labor management in patients testing negative for fetal fibronectin","volume":"25","author":"Elliott","year":"2005","journal-title":"Journal of Perinatology"},{"issue":"2","key":"10.1002\/14651858.CD006843.pub2-BIB0012|cit12","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1067\/mob.2001.115998","article-title":"Metronidazole treatment of women with a positive fetal fibronectin test result","volume":"185","author":"Goldenberg","year":"2001","journal-title":"American Journal of Obstetrics and Gynecology"},{"issue":"6 Suppl","key":"10.1002\/14651858.CD006843.pub2-BIB0013|cit13","doi-asserted-by":"crossref","first-page":"S86","DOI":"10.1016\/S0002-9378(01)80071-5","article-title":"Mid-trimester metronidazole and azithromycin did not prevent preterm birth in women at increased risk: a double-blind trial [abstract]","volume":"185","author":"Hauth","year":"2001","journal-title":"American Journal of Obstetrics and Gynecology"},{"issue":"4 Suppl","key":"10.1002\/14651858.CD006843.pub2-BIB0014|cit14","doi-asserted-by":"crossref","first-page":"51S","DOI":"10.1016\/S0029-7844(99)90112-6","article-title":"A randomized comparison of specimen collection methods for the fetal fibronectin immunoassay [abstract]","volume":"93","author":"Kalchbrenner","year":"1999","journal-title":"Obstetrics & Gynecology"},{"key":"10.1002\/14651858.CD006843.pub2-BIB0015|cit15","unstructured":"Lachelin GCL Randomised double blind placebo controlled trial of antimicrobial treatment in pregnant women at risk of preterm labour http:\/\/controlled-trials.com\/mrct"},{"issue":"1","key":"10.1002\/14651858.CD006843.pub2-BIB0016|cit16","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1111\/j.1471-0528.2005.00788.x","article-title":"A randomised controlled trial of metronidazole for the prevention of preterm birth in women positive for cervicovaginal fetal fibronectin: the PREMET Study","volume":"113","author":"Shennan","year":"2006","journal-title":"BJOG: an international journal of obstetrics and gynaecology."},{"key":"10.1002\/14651858.CD006843.pub2-BIB0017|cit17","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1097\/01.AOG.0000168435.17200.53","article-title":"Cerclage for a short cervix on ultrasonography: meta-analysis of trials using individual patient-level data","volume":"106","author":"Berghella","year":"2005","journal-title":"Obstetrics & Gynecology"},{"key":"10.1002\/14651858.CD006843.pub2-BIB0018|cit18","doi-asserted-by":"crossref","DOI":"10.1002\/9780470693926.ch15","article-title":"Statistical methods for examining heterogeneity and combining results from several studies in meta-analysis","volume-title":"Systematic reviews in health care: meta-analysis in context","author":"Deeks","year":"2001"},{"issue":"1","key":"10.1002\/14651858.CD006843.pub2-BIB0019|cit19","doi-asserted-by":"crossref","DOI":"10.1002\/14651858.CD004947.pub2","article-title":"Prenatal administration of progesterone for preventing preterm birth","author":"Dodd","year":"2006","journal-title":"Cochrane Database of Systematic Reviews"},{"issue":"1","key":"10.1002\/14651858.CD006843.pub2-BIB0020|cit20","article-title":"Cervical stitch (cerclage) for preventing pregnancy loss in women","author":"Drakeley","year":"2003","journal-title":"Cochrane Database of Systematic Reviews"},{"key":"10.1002\/14651858.CD006843.pub2-BIB0021|cit21","doi-asserted-by":"crossref","unstructured":"Higgins JPT Green S Cochrane Handbook for Systematic Reviews of Interventions 4.2.5 [updated March 2005] In: The Cochrane Library, Issue 3, 2005. Chichester, UK: John Wiley & Sons, Ltd 2005 10.1002\/14651858","DOI":"10.1002\/14651858"},{"issue":"2","key":"10.1002\/14651858.CD006843.pub2-BIB0022|cit22","doi-asserted-by":"crossref","DOI":"10.1002\/14651858.CD001992.pub2","article-title":"Cyclooxygenase (COX) inhibitors for treating preterm labour","author":"King","year":"2005","journal-title":"Cochrane Database of Systematic Reviews"},{"issue":"5","key":"10.1002\/14651858.CD006843.pub2-BIB0023|cit23","doi-asserted-by":"crossref","first-page":"1169","DOI":"10.1016\/S0002-9378(99)70612-5","article-title":"Cervico-vaginal fetal fibronectin as a marker for preterm delivery: a meta-analysis","volume":"180","author":"Leitich","year":"1999","journal-title":"American Journal of Obstetrics and Gynecology"},{"issue":"4","key":"10.1002\/14651858.CD006843.pub2-BIB0024|cit24","doi-asserted-by":"crossref","DOI":"10.1002\/14651858.CD001055.pub2","article-title":"Interventions for promoting smoking cessation during pregnancy","author":"Lumley","year":"2004","journal-title":"Cochrane Database of Systematic Reviews"},{"key":"10.1002\/14651858.CD006843.pub2-BIB0025|cit25","unstructured":"The Nordic Cochrane Centre, The Cochrane Collaboration Review Manager (RevMan) 2008"},{"issue":"3","key":"10.1002\/14651858.CD006843.pub2-BIB0026|cit26","doi-asserted-by":"publisher","DOI":"10.1002\/14651858","article-title":"Antenatal corticosteroids for accelerating fetal lung maturation for women at risk for preterm birth","author":"Roberts","year":"2006","journal-title":"Cochrane Database of Systematic Reviews"},{"issue":"2","key":"10.1002\/14651858.CD006843.pub2-BIB0027|cit27","doi-asserted-by":"crossref","DOI":"10.1002\/14651858.CD000490","article-title":"Antibiotics for asymptomatic bacteriuria in pregnancy","author":"Smaill","year":"2001","journal-title":"Cochrane Database of Systematic Reviews"}],"updated-by":[{"DOI":"10.1002\/14651858.cd006843.pub3","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2019,7,29]],"date-time":"2019-07-29T00:00:00Z","timestamp":1564358400000}}],"container-title":["Cochrane Database of Systematic Reviews"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full\/10.1002\/14651858.CD006843.pub2","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,8,9]],"date-time":"2021-08-09T22:04:23Z","timestamp":1628546663000},"score":1,"resource":{"primary":{"URL":"https:\/\/doi.wiley.com\/10.1002\/14651858.CD006843.pub2"}},"subtitle":[],"editor":[{"name":"Cochrane Pregnancy and Childbirth Group","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2008,10,8]]},"references-count":27,"URL":"https:\/\/doi.org\/10.1002\/14651858.cd006843.pub2","relation":{"new_version":[{"id-type":"doi","id":"10.1002\/14651858.CD006843.pub3","asserted-by":"object"}]},"ISSN":["1465-1858"],"issn-type":[{"value":"1465-1858","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,10,8]]}}}