{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T21:05:31Z","timestamp":1792875931852,"version":"4.5.0"},"update-to":[{"DOI":"10.1002\/14651858.cd006887.pub3","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2017,3,14]],"date-time":"2017-03-14T00:00:00Z","timestamp":1489449600000}}],"reference-count":221,"publisher":"Wiley","issue":"6","content-domain":{"domain":["wiley.com","cochranelibrary.com"],"crossmark-restriction":true},"short-container-title":[],"DOI":"10.1002\/14651858.cd006887.pub4","type":"journal-article","created":{"date-parts":[[2017,3,14]],"date-time":"2017-03-14T11:40:33Z","timestamp":1489491633000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":56,"title":["Risk scoring for the primary prevention of cardiovascular disease"],"prefix":"10.1002","volume":"2021","author":[{"given":"Kunal N","family":"Karmali","sequence":"additional","affiliation":[{"name":"Departments of Medicine (Cardiology); Northwestern University Feinberg School of Medicine; Chicago IL USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen D","family":"Persell","sequence":"additional","affiliation":[{"name":"Department of Medicine-General Internal Medicine and Geriatrics; Northwestern University; Chicago Illinois USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pablo","family":"Perel","sequence":"additional","affiliation":[{"name":"Faculty of Epidemiology and Population Health; London School of Hygiene and Tropical Medicine; London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Donald M","family":"Lloyd-Jones","sequence":"additional","affiliation":[{"name":"Departments of Preventive Medicine and Medicine (Cardiology); Northwestern University Feinberg School of Medicine; Chicago IL USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark A","family":"Berendsen","sequence":"additional","affiliation":[{"name":"Galter Health Sciences Library; Northwestern University; Chicago IL USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark D","family":"Huffman","sequence":"additional","affiliation":[{"name":"Departments of Preventive Medicine and Medicine (Cardiology); Northwestern University Feinberg School of Medicine; Chicago IL USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,3,14]]},"reference":[{"key":"10.1002\/14651858.CD006887.pub4-BIB0001|cit1","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1016\/j.cct.2007.03.004","article-title":"Rationale, design, and methods for the risk evaluation and communication health outcomes and utilization trial (REACH OUT)","volume":"28","author":"Benner","year":"2007","journal-title":"Contemporary Clinical Trials"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0002|cit2","doi-asserted-by":"crossref","first-page":"1484","DOI":"10.1111\/j.1742-1241.2008.01872.x","article-title":"A novel programme to evaluate and communicate 10-year risk of CHD reduces predicted risk and improves patients' modifiable risk factor profile","volume":"62","author":"Benner","year":"2008","journal-title":"International Journal of Clinical Practice"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0003|cit3","doi-asserted-by":"crossref","first-page":"678","DOI":"10.1001\/archinternmed.2009.44","article-title":"Impact of a multifaceted intervention on cholesterol management in primary care practices: guideline adherence for heart health randomized trial","volume":"169","author":"Bertoni","year":"2009","journal-title":"Archives of Internal Medicine"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0004|cit4","first-page":"62","article-title":"British family heart study: its design and method, and prevalence of cardiovascular risk factors","volume":"44","author":"Family Heart Study Group","year":"1994","journal-title":"British Journal of General Practice"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0005|cit5","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1136\/bmj.308.6924.313","article-title":"Randomised controlled trial evaluating cardiovascular screening and intervention in general practice: principal results of British family heart study","volume":"308","author":"Family Heart Study Group","year":"1994","journal-title":"BMJ"},{"issue":"1","key":"10.1002\/14651858.CD006887.pub4-BIB0006|cit6","doi-asserted-by":"crossref","first-page":"31","DOI":"10.3851\/IMP1475","article-title":"Randomized trial of a computerized coronary heart disease risk assessment tool in HIV-infected patients receiving combination antiretroviral therapy","volume":"15","author":"Bucher","year":"2010","journal-title":"Antiviral Therapy"},{"issue":"3","key":"10.1002\/14651858.CD006887.pub4-BIB0007|cit7","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1097\/01.hjr.0000129739.30593.23","article-title":"No long-term psychological reaction to information about increased risk of coronary heart disease in general practice","volume":"11","author":"Christensen","year":"2004","journal-title":"European Journal of Cardiovascular Prevention and Rehabilitation"},{"issue":"6","key":"10.1002\/14651858.CD006887.pub4-BIB0008|cit8","doi-asserted-by":"crossref","first-page":"421","DOI":"10.2165\/00115677-200513060-00007","article-title":"Cost effectiveness of a clinical decision support system based on the recommendations of the European Society of Cardiology and other societies for the management of hypercholesterolemia: Report of a cluster-randomized trial","volume":"13","author":"Cobos","year":"2005","journal-title":"Disease Management and Health Outcomes"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0009|cit9","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1186\/1745-6215-13-219","article-title":"The effect of a patient-oriented treatment decision aid for risk factor management in patients with diabetes (PORTDA-diab): study protocol for a randomised controlled trial","volume":"13","author":"Denig","year":"2012","journal-title":"Trials"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0010|cit10","doi-asserted-by":"crossref","first-page":"g5651","DOI":"10.1136\/bmj.g5651","article-title":"Effects of a patient oriented decision aid for prioritising treatment goals in diabetes: pragmatic randomised controlled trial","volume":"349","author":"Denig","year":"2014","journal-title":"BMJ"},{"issue":"6","key":"10.1002\/14651858.CD006887.pub4-BIB0011|cit11","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1370\/afm.1297","article-title":"Translating cholesterol guidelines into primary care practice: a multimodal cluster randomized trial","volume":"9","author":"Eaton","year":"2011","journal-title":"Annals of Family Medicine"},{"issue":"7","key":"10.1002\/14651858.CD006887.pub4-BIB0012|cit12","doi-asserted-by":"crossref","first-page":"728","DOI":"10.1111\/j.1525-1497.2006.00495.x","article-title":"A multidimensional integrative medicine intervention to improve cardiovascular risk","volume":"21","author":"Edelman","year":"2006","journal-title":"Journal of General Internal Medicine"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0013|cit13","first-page":"3354","article-title":"Can systematic general health checks and health discussions improve the cardiovascular risk profile in the population?: A randomized and controlled study in general practice with five years follow-up","volume":"164","author":"Engberg","year":"2002","journal-title":"Ugeskrift for Laeger"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0014|cit14","first-page":"546","article-title":"General health screenings to improve cardiovascular risk profiles: a randomized controlled trial in general practice with 5-year follow-up","volume":"51","author":"Engberg","year":"2002","journal-title":"Journal of Family Practice"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0015|cit15","first-page":"542","article-title":"Ebeltoft project: baseline data from a five-year randomized, controlled, prospective health promotion study in a Danish population","volume":"45","author":"Lauritzen","year":"1995","journal-title":"British Journal of General Practice"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0016|cit16","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1007\/s11606-008-0825-4","article-title":"Discussing coronary risk with patients to improve blood pressure treatment: secondary results from the CHECK-UP study","volume":"24","author":"Grover","year":"2009","journal-title":"Journal of General Internal Medicine"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0017|cit17","doi-asserted-by":"crossref","first-page":"2296","DOI":"10.1001\/archinte.167.21.2296","article-title":"Patient knowledge of coronary risk profile improves the effectiveness of dyslipidemia therapy - The CHECK-UP study: a randomized controlled trial","volume":"167","author":"Grover","year":"2007","journal-title":"Archives of Internal Medicine"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0018|cit18","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1136\/bmj.326.7383.251","article-title":"Controlled trial of effect of documented cardiovascular risk scores on prescribing","volume":"326","author":"Hall","year":"2003","journal-title":"BMJ"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0019|cit19","doi-asserted-by":"crossref","first-page":"1609","DOI":"10.1136\/bmj.311.7020.1609","article-title":"Health checks and coronary risk: further evidence from a randomised controlled trial","volume":"311","author":"Hanlon","year":"1995","journal-title":"BMJ"},{"issue":"8","key":"10.1002\/14651858.CD006887.pub4-BIB0020|cit20","first-page":"943","article-title":"The estimation of cardiovascular risk in hypertensive patients is not modified by management of the hypertension","volume":"93","author":"Hanon","year":"2000","journal-title":"Archives des Maladies du Coeur et des Vaisseaux"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0021|cit21","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1080\/028134399750002872","article-title":"Implementing clinical guidelines in the treatment of hypertension in general practice. Evaluation of patient outcome related to implementation of a computer-based clinical decision support system","volume":"17","author":"Hetlevik","year":"1999","journal-title":"Scandinavian Journal of Primary Health Care"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0022|cit22","doi-asserted-by":"crossref","first-page":"e137","DOI":"10.3399\/bjgp10X483904","article-title":"Automated electronic reminders to facilitate primary cardiovascular disease prevention: randomised controlled trial","volume":"60","author":"Holt","year":"2010","journal-title":"British Journal of General Practice"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0023|cit23","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1186\/1745-6215-7-11","article-title":"Protocol for the 'e-Nudge trial': A randomised controlled trial of electronic feedback to reduce the cardiovascular risk of individuals in general practice [ISRCTN64828380]","volume":"7","author":"Holt","year":"2006","journal-title":"Trials"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0024|cit24","doi-asserted-by":"crossref","first-page":"1065","DOI":"10.1185\/030079906X104605","article-title":"Effects of a global risk educational tool on primary coronary prevention: the Atherosclerosis Assessment ViaTotal Risk (AVIATOR) study","volume":"22","author":"Jacobson","year":"2006","journal-title":"Current Medical Research and Opinion"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0025|cit25","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1186\/s12966-015-0195-3","article-title":"The long-term effect of screening and lifestyle counseling on changes in physical activity and diet: the Inter99 Study - a randomized controlled trial","volume":"12","author":"Baumann","year":"2015","journal-title":"International Journal of Behavioral Nutrition and Physical Activity"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0026|cit26","doi-asserted-by":"crossref","first-page":"g3617","DOI":"10.1136\/bmj.g3617","article-title":"Effect of screening and lifestyle counselling on incidence of ischaemic heart disease in general population: Inter99 randomised trial","volume":"348","author":"Jorgensen","year":"2014","journal-title":"BMJ"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0027|cit27","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1016\/j.ypmed.2008.12.010","article-title":"Screening for risk of cardiovascular disease is not associated with mental distress: the Inter99 study","volume":"48","author":"Jorgensen","year":"2009","journal-title":"Preventive Medicine"},{"issue":"6","key":"10.1002\/14651858.CD006887.pub4-BIB0028|cit28","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1016\/j.ypmed.2008.02.026","article-title":"High risk strategy in smoking cessation is feasible on a population-based level. The Inter99 study","volume":"46","author":"Pisinger","year":"2008","journal-title":"Preventive Medicine"},{"issue":"4","key":"10.1002\/14651858.CD006887.pub4-BIB0029|cit29","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1016\/j.ypmed.2008.05.013","article-title":"The impact of a population-based multi-factorial lifestyle intervention on changes in long-term dietary habits: the Inter99 study","volume":"47","author":"Toft","year":"2008","journal-title":"Preventive Medicine"},{"issue":"4","key":"10.1002\/14651858.CD006887.pub4-BIB0030|cit30","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1177\/1403494807085313","article-title":"A randomized multifactorial intervention study for prevention of ischaemic heart disease (Inter99): the long-term effect on physical activity","volume":"36","author":"Von Huth Smith","year":"2008","journal-title":"Scandinavian Journal of Public Health"},{"issue":"1-2","key":"10.1002\/14651858.CD006887.pub4-BIB0031|cit31","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.ypmed.2009.11.007","article-title":"Improving lifestyle and risk perception through patient involvement in nurse-led cardiovascular risk management: a cluster-randomized controlled trial in primary care","volume":"50","author":"Koelewijn-van Loon","year":"2010","journal-title":"Preventive Medicine"},{"issue":"12","key":"10.1002\/14651858.CD006887.pub4-BIB0032|cit32","doi-asserted-by":"crossref","first-page":"E267","DOI":"10.1503\/cmaj.081591","article-title":"Involving patients in cardiovascular risk management with nurse-led clinics: a cluster randomized controlled trial","volume":"181","author":"Koelewijn-van Loon","year":"2009","journal-title":"Canadian Medical Association Journal"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0033|cit33","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1186\/1472-6963-8-9","article-title":"Improving patient adherence to lifestyle advice (IMPALA): a cluster-randomised controlled trial on the implementation of a nurse-led intervention for cardiovascular risk management in primary care [protocol]","volume":"8","author":"Koelewijn-van Loon","year":"2008","journal-title":"BMC Health Services Research"},{"issue":"3","key":"10.1002\/14651858.CD006887.pub4-BIB0034|cit34","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1177\/1741826711404502","article-title":"Arriba: effects of an educational intervention on prescribing behaviour in prevention of CVD in general practice","volume":"19","author":"Keller","year":"2012","journal-title":"European Journal of Preventive Cardiology"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0035|cit35","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1370\/afm.854","article-title":"Absolute cardiovascular disease risk and shared decision making in primary care: a randomized controlled trial","volume":"6","author":"Krones","year":"2008","journal-title":"Annals of Family Medicine"},{"issue":"3","key":"10.1002\/14651858.CD006887.pub4-BIB0036|cit36","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1177\/2047487313518479","article-title":"Effectiveness of the Heart Age tool for improving modifiable cardiovascular risk factors in a Southern European population: a randomized trial","volume":"22","author":"Lopez-Gonzalez","year":"2015","journal-title":"European Journal of Preventive Cardiology"},{"issue":"5 Pt 1","key":"10.1002\/14651858.CD006887.pub4-BIB0037|cit37","doi-asserted-by":"crossref","first-page":"730","DOI":"10.1006\/pmed.1998.0351","article-title":"Can computerized risk profiles help patients improve their coronary risk? The results of the Coronary Health Assessment Study (CHAS)","volume":"27","author":"Lowensteyn","year":"1998","journal-title":"Preventive Medicine"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0038|cit38","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1016\/j.pec.2009.10.008","article-title":"The Statin Choice decision aid in primary care: a randomized trial","volume":"80","author":"Mann","year":"2010","journal-title":"Patient Education and Counseling"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0039|cit39","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1186\/1472-6963-1-10","article-title":"Randomized trial evaluating the framing of cardiovascular risk and its impact on blood pressure control [ISRCTN87597585]","volume":"1","author":"Fahey","year":"2001","journal-title":"BMC Health Services Research"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0040|cit40","doi-asserted-by":"crossref","first-page":"686","DOI":"10.1136\/bmj.320.7236.686","article-title":"Evaluation of computer based clinical decision support system and risk chart for management of hypertension in primary care: randomised controlled trial","volume":"320","author":"Montgomery","year":"2000","journal-title":"BMJ"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0041|cit41","first-page":"551","article-title":"Three-year follow-up of a factorial randomised controlled trial of two decision aids for newly diagnosed hypertensive patients","volume":"55","author":"Emmett","year":"2005","journal-title":"British Journal of General Practice"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0042|cit42","first-page":"446","article-title":"A factorial randomised controlled trial of decision analysis and an information video plus leaflet for newly diagnosed hypertensive patients","volume":"53","author":"Montgomery","year":"2003","journal-title":"British Journal of General Practice"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0043|cit43","first-page":"e808","article-title":"Health Tracker: does electronic decision support improve identification and management of cardiovascular risk in Australian primary health care?","volume":"125","author":"Panaretto","year":"2012","journal-title":"Circulation"},{"issue":"6","key":"10.1002\/14651858.CD006887.pub4-BIB0044|cit44","doi-asserted-by":"crossref","first-page":"e002177","DOI":"10.1136\/bmjopen-2012-002177","article-title":"The treatment of cardiovascular risk in primary care using electronic decision support (TORPEDO) study: Intervention development and protocol for a cluster randomised, controlled trial of an electronic decision support and quality improvement intervention in Australian primary healthcare","volume":"2","author":"Peiris","year":"2012","journal-title":"BMJ Open"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0045|cit45","first-page":"87","article-title":"Effect of a computer-guided, quality improvement program for cardiovascular disease risk management in primary health care: the treatment of cardiovascular risk using electronic decision support cluster-randomized trial","volume":"8","author":"Peiris","year":"2015","journal-title":"Circulation: Cardiovascular Quality and Outcomes"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0046|cit46","doi-asserted-by":"crossref","first-page":"e28","DOI":"10.1016\/j.gheart.2014.03.1317","article-title":"Effect of a multi-faceted quality improvement intervention to improve cardiovascular disease risk identification and management in Australian primary health care: the torpedo cluster-randomised trial","volume":"9","author":"Peiris","year":"2014","journal-title":"Global Heart"},{"issue":"2","key":"10.1002\/14651858.CD006887.pub4-BIB0047|cit47","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/j.pec.2015.08.032","article-title":"Effect of the statin choice encounter decision aid in Spanish patients with type 2 diabetes: a randomized trial","volume":"99","author":"Perestelo-Perez","year":"2016","journal-title":"Patient Education and Counseling"},{"issue":"4","key":"10.1002\/14651858.CD006887.pub4-BIB0048|cit48","doi-asserted-by":"crossref","first-page":"554","DOI":"10.1007\/s11606-012-2268-1","article-title":"Electronic health record-based patient identification and individualized mailed outreach for primary cardiovascular disease prevention: a cluster randomized trial","volume":"28","author":"Persell","year":"2013","journal-title":"Journal of General Internal Medicine"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0049|cit49","first-page":"S181","article-title":"Electronic health record-based patient identification and individualized mailed outreach for primary cardiovascular disease prevention: a cluster randomized trial","volume":"27","author":"Persell","year":"2012","journal-title":"Journal of General Internal Medicine"},{"issue":"6","key":"10.1002\/14651858.CD006887.pub4-BIB0050|cit50","first-page":"560","article-title":"Individualized risk communication and outreach for primary cardiovascular disease prevention in community health centers: randomized trial","volume":"8","author":"Persell","year":"2015","journal-title":"Circulation: Cardiovascular Quality and Outcomes"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0051|cit51","first-page":"A14008","article-title":"Individualized risk communication and lay outreach for the primary prevention of cardiovascular disease in community health centers: a randomized controlled trial","volume":"130","author":"Persell","year":"2014","journal-title":"Circulation"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0052|cit52","first-page":"S126","article-title":"Individualized risk communication and lay outreach for the primary prevention of cardiovascular disease in community health centers: preliminary results of a randomized controlled trial","volume":"29","author":"Shah","year":"2014","journal-title":"Journal of General Internal Medicine"},{"issue":"3","key":"10.1002\/14651858.CD006887.pub4-BIB0053|cit53","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1111\/j.1464-5491.2010.03212.x","article-title":"Impact of personalized cardiovascular disease risk estimates on physical activity-a randomized controlled trial","volume":"28","author":"Price","year":"2011","journal-title":"Diabetic Medicine"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0054|cit54","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1186\/1475-2840-7-21","article-title":"The impact of individualised cardiovascular disease (CVD) risk estimates and lifestyle advice on physical activity in individuals at high risk of CVD: a pilot 2 x 2 factorial understanding risk trial","volume":"7","author":"Price","year":"2008","journal-title":"Cardiovascular Diabetology"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0055|cit55","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1186\/1472-6963-6-121","article-title":"The impact of a decision aid about heart disease prevention on patients' discussions with their doctor and their plans for prevention: a pilot randomized trial","volume":"6","author":"Sheridan","year":"2006","journal-title":"BMC Health Services Research"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0056|cit56","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1186\/1472-6963-11-331","article-title":"A randomized trial of an intervention to improve use and adherence to effective coronary heart disease prevention strategies","volume":"11","author":"Sheridan","year":"2011","journal-title":"BMC Health Services Research"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0057|cit57","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1186\/1472-6947-14-14","article-title":"The effect of a decision aid intervention on decision making about coronary heart disease risk reduction: secondary analyses of a randomized trial","volume":"14","author":"Sheridan","year":"2014","journal-title":"BMC Medical Informatics and Decision Making"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0058|cit58","doi-asserted-by":"crossref","first-page":"e100","DOI":"10.2196\/jmir.1579","article-title":"Web-based risk communication and planning in an obese population: exploratory study","volume":"13","author":"Soureti","year":"2011","journal-title":"Journal of Medical Internet Research"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0059|cit59","doi-asserted-by":"crossref","first-page":"1258","DOI":"10.1007\/s11606-012-2095-4","article-title":"A randomized trial of peer coach and office staff support to reduce coronary heart disease risk in African-Americans with uncontrolled hypertension","volume":"27","author":"Turner","year":"2012","journal-title":"Journal General Internal Medicine"},{"issue":"1","key":"10.1002\/14651858.CD006887.pub4-BIB0060|cit60","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/j.ahj.2013.10.002","article-title":"Influence of cardiovascular absolute risk assessment on prescribing of antihypertensive and lipid-lowering medications: a cluster randomized controlled trial","volume":"167","author":"Vagholkar","year":"2014","journal-title":"American Heart Journal"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0061|cit61","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1016\/j.ahj.2008.11.016","article-title":"Study protocol for a randomized controlled trial: the feasibility and impact of cardiovascular absolute risk assessment in Australian general practice","volume":"157","author":"Wan","year":"2009","journal-title":"American Heart Journal"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0062|cit62","first-page":"44","article-title":"Improving cardiovascular risk management: a randomized, controlled trial on the effect of a decision support tool for patients and physicians","volume":"14","author":"Van Steenkiste","year":"2007","journal-title":"European Journal of Prevention and Rehabilitation"},{"issue":"1","key":"10.1002\/14651858.CD006887.pub4-BIB0063|cit63","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/j.pec.2008.02.009","article-title":"Patients' responsiveness to a decision support tool for primary prevention of cardiovascular diseases in primary care 1498","volume":"72","author":"Van Steenkiste","year":"2008","journal-title":"Patient Education and Counseling"},{"issue":"3","key":"10.1002\/14651858.CD006887.pub4-BIB0064|cit64","doi-asserted-by":"crossref","first-page":"e42","DOI":"10.2196\/jmir.1364","article-title":"Effects of internet-based tailored advice on the use of cholesterol-lowering interventions: a randomized controlled trial","volume":"12","author":"Webster","year":"2010","journal-title":"Journal of Medical Internet Research"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0065|cit65","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1186\/1471-2458-10-457","article-title":"The @RISK Study: Risk communication for patients with type 2 diabetes: design of a randomised controlled trial","volume":"10","author":"Welschen","year":"2010","journal-title":"BMC Public Health"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0066|cit66","doi-asserted-by":"crossref","first-page":"2485","DOI":"10.2337\/dc11-2130","article-title":"Effects of cardiovascular disease risk communication for patients with type 2 diabetes on risk perception in a randomized controlled trial: the @RISK study","volume":"35","author":"Welschen","year":"2012","journal-title":"Diabetes Care"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0067|cit67","first-page":"S487","article-title":"Cardiovascular disease risk communication for patients with type 2 diabetes: the @RISK study","volume":"53","author":"Welschen","year":"2010","journal-title":"Diabetologia"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0068|cit68","doi-asserted-by":"crossref","first-page":"1288","DOI":"10.1111\/j.1525-1497.2006.00621.x","article-title":"A self-determination multiple risk intervention trial to improve smokers' health","volume":"21","author":"Williams","year":"2006","journal-title":"Journal of General Internal Medicine"},{"issue":"5","key":"10.1002\/14651858.CD006887.pub4-BIB0069|cit69","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1093\/her\/17.5.512","article-title":"Self-determination, smoking, diet and health","volume":"17","author":"Williams","year":"2002","journal-title":"Health Education Research"},{"issue":"8","key":"10.1002\/14651858.CD006887.pub4-BIB0070|cit70","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1503\/cmaj.061059","article-title":"One-year follow-up of a therapeutic lifestyle intervention targeting cardiovascular disease risk","volume":"177","author":"Wister","year":"2007","journal-title":"Canadian Medical Association Journal"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0071|cit71","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1177\/1357633X14528446","article-title":"A randomised controlled trial of providing personalised cardiovascular risk information to modify health behaviour","volume":"20","author":"Zullig","year":"2014","journal-title":"Journal of Telemedicine and Telecare"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0072|cit72","doi-asserted-by":"crossref","first-page":"924","DOI":"10.1186\/1471-2458-14-924","article-title":"A cluster-randomized controlled trial to evaluate the effects of a simplified cardiovascular management program in Tibet, China and Haryana, India: study design and rationale","volume":"14","author":"Ajay","year":"2014","journal-title":"BMC Public Health"},{"issue":"6","key":"10.1002\/14651858.CD006887.pub4-BIB0073|cit73","first-page":"595","article-title":"Community Outreach and Cardiovascular Health (COACH) Trial: a randomized, controlled trial of nurse practitioner\/community health worker cardiovascular disease risk reduction in urban community health centers","volume":"4","author":"Allen","year":"2011","journal-title":"Circulation: Cardiovascular Quality and Outcomes"},{"issue":"12","key":"10.1002\/14651858.CD006887.pub4-BIB0074|cit74","doi-asserted-by":"crossref","first-page":"1608","DOI":"10.2105\/AJPH.79.12.1608","article-title":"Accuracy of perceptions of heart attack risk: what influences perceptions and can they be changed?","volume":"79","author":"Avis","year":"1989","journal-title":"American Journal of Public Health"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0075|cit75","doi-asserted-by":"crossref","first-page":"53","DOI":"10.2147\/IJGM.S15686","article-title":"Changes in CVD risk factors in the activity counseling trial","volume":"4","author":"Baruth","year":"2011","journal-title":"International Journal of General Medicine"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0076|cit76","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1097\/HPC.0b013e31815b5609","article-title":"Implementing cardiac risk-factor case management: lessons learned in a county health system","volume":"6","author":"Berra","year":"2007","journal-title":"Critical Pathways in Cardiology"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0077|cit77","first-page":"S3","article-title":"Can a multimodale intervention improve exercise capacity in patients with high cardiovascular risk on a sustained basis-the PreFord-study","volume":"20","author":"Bjarnason-Wehrens","year":"2013","journal-title":"European Journal of Preventive Cardiology"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0078|cit78","first-page":"A17097","article-title":"Substantial improvement of primary cardiovascular prevention by a systematic score-based multimodal and lifestyle approach: a randomized endpoint-study-the Preford-study","volume":"132","author":"Predel","journal-title":"Circulation"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0079|cit79","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1111\/dme.12410","article-title":"Does early intensive multifactorial therapy reduce modelled cardiovascular risk in individuals with screen-detected diabetes? Results from the ADDITION-Europe cluster randomized trial","volume":"31","author":"Black","year":"2014","journal-title":"Diabetic Medicine"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0080|cit80","first-page":"227","article-title":"How does intensive therapy to control cardiovascular risk factors affect health-related quality of life in diabetic patients?","volume":"39","author":"Botija-Yague","year":"2007","journal-title":"Atencion Primaria"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0081|cit81","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1186\/1472-6963-13-301","article-title":"Shared decision making for patients with type 2 diabetes: a randomized trial in primary care","volume":"13","author":"Branda","year":"2013","journal-title":"BMC Health Services Research"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0082|cit82","doi-asserted-by":"crossref","first-page":"e22","DOI":"10.3399\/bjgp12X616337","article-title":"The Fremantle Primary Prevention Study: a multicentre randomised trial of absolute cardiovascular risk reduction","volume":"62","author":"Brett","year":"2012","journal-title":"British Journal of General Practice"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0083|cit83","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1007\/s10557-008-6137-4","article-title":"Effect of an educational program (PEGASE) on cardiovascular risk in hypercholesterolaemic patients","volume":"22","author":"Bruckert","year":"2008","journal-title":"Cardiovascular Drugs and Therapy"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0084|cit84","first-page":"1063","article-title":"Preliminary results of the impress study: reducing cardiovascular risk factors in a nurse-led primary intervention program for high risk participants","volume":"33","author":"Carrington","year":"2012","journal-title":"European Heart Journal"},{"issue":"2","key":"10.1002\/14651858.CD006887.pub4-BIB0085|cit85","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1016\/j.diabres.2012.09.023","article-title":"Improving diabetes care: multi-component cardiovascular disease risk reduction strategies for people with diabetes in South Asia--the CARRS multi-center translation trial","volume":"98","author":"Shah","year":"2012","journal-title":"Diabetes Research and Clinical Practice"},{"issue":"4","key":"10.1002\/14651858.CD006887.pub4-BIB0086|cit86","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1093\/heapro\/dap030","article-title":"Implementing a standardized community-based cardiovascular risk assessment program in 20 Ontario communities","volume":"24","author":"Carter","year":"2009","journal-title":"Health Promotion International"},{"issue":"7","key":"10.1002\/14651858.CD006887.pub4-BIB0087|cit87","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1002\/phar.1603","article-title":"A cluster-randomized trial of a centralized clinical pharmacy cardiovascular risk service to improve guideline adherence","volume":"35","author":"Carter","year":"2015","journal-title":"Pharmacotherapy"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0088|cit88","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1016\/j.ahj.2009.05.034","article-title":"Rationale and design of the Rural Andhra Pradesh Cardiovascular Prevention Study (RAPCAPS): a factorial, cluster-randomized trial of 2 practical cardiovascular disease prevention strategies developed for rural Andhra Pradesh, India","volume":"158","author":"Chow","year":"2009","journal-title":"American Heart Journal"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0089|cit89","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1186\/1471-2261-7-27","article-title":"The PreCardio-study protocol--a randomized clinical trial of a multidisciplinary electronic cardiovascular prevention programme","volume":"7","author":"Claes","year":"2007","journal-title":"BMC Cardiovascular Disorders"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0090|cit90","doi-asserted-by":"crossref","first-page":"2273","DOI":"10.2337\/dc08-0312","article-title":"Combined task delegation, computerized decision support, and feedback improve cardiovascular risk for type 2 diabetic patients: a cluster randomized trial in primary care","volume":"31","author":"Cleveringa","year":"2008","journal-title":"Diabetes Care"},{"issue":"2","key":"10.1002\/14651858.CD006887.pub4-BIB0091|cit91","doi-asserted-by":"crossref","first-page":"258","DOI":"10.2337\/dc09-1232","article-title":"Cost-effectiveness of the diabetes care protocol, a multifaceted computerized decision support diabetes management intervention that reduces cardiovascular risk","volume":"33","author":"Cleveringa","year":"2010","journal-title":"Diabetes Care"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0092|cit92","first-page":"S117","article-title":"Task delegation and computerised decision support improve cardiovascular risk for type 2 diabetes patients. A randomised controlled trial in primary care","volume":"50","author":"Cleveringa","year":"2007","journal-title":"Diabetologia"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0093|cit93","doi-asserted-by":"crossref","first-page":"944","DOI":"10.1186\/1471-2458-12-944","article-title":"NHS health checks through general practice: randomised trial of population cardiovascular risk reduction","volume":"12","author":"Cochrane","year":"2012","journal-title":"BMC Public Health"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0094|cit94","first-page":"S406","article-title":"Does a PDA improve knowledge about treatment choices for patients with type 2 diabetes mellitus when making decisions about starting insulin? Quantitative analysis from the PANDAs study","volume":"54","author":"Colwell","year":"2011","journal-title":"Diabetologia"},{"issue":"3-4","key":"10.1002\/14651858.CD006887.pub4-BIB0095|cit95","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/S0027-9684(15)30139-5","article-title":"Increasing knowledge of cardiovascular risk factors among African Americans by use of community health workers: the ABCD community intervention pilot project","volume":"104","author":"Daniels","year":"2012","journal-title":"Journal of the National Medical Association"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0096|cit96","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1016\/j.numecd.2013.11.008","article-title":"Care manager to control cardiovascular risk factors in primary care: the Raffaello cluster randomized trial","volume":"24","author":"Deales","year":"2014","journal-title":"Nutrition, Metabolism & Cardiovascular Diseases"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0097|cit97","first-page":"219","article-title":"Project Raffaello: Application and evaluation of the disease and care management approach in cardiovascular disease prevention","volume":"32","author":"Romano","year":"2011","journal-title":"European Heart Journal"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0098|cit98","first-page":"A57","article-title":"Compliance with prescribed therapy and patient perceptions in the treatment of hypertension","volume":"11","author":"Dresser","year":"2009","journal-title":"Journal of Clinical Hypertension"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0099|cit99","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1016\/j.pec.2005.12.016","article-title":"Presenting risk information to people with diabetes: evaluating effects and preferences for different formats by a web-based randomised controlled trial","volume":"63","author":"Edwards","year":"2006","journal-title":"Patient Education and Counseling"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0100|cit100","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1097\/HJR.0b013e3282fceac2","article-title":"Intensified preventive care to reduce cardiovascular risk in healthcare centres located in deprived neighbourhoods: a randomized controlled trial","volume":"15","author":"El Fakiri","year":"2008","journal-title":"European Journal of Cardiovascular Prevention and Rehabilitation"},{"issue":"8","key":"10.1002\/14651858.CD006887.pub4-BIB0101|cit101","doi-asserted-by":"crossref","first-page":"766","DOI":"10.1592\/phco.30.8.766","article-title":"The Collaborative Cardiovascular Risk Reduction in Primary Care (CCARP) study","volume":"30","author":"Evans","year":"2010","journal-title":"Pharmacotherapy"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0102|cit102","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1186\/1471-2296-15-135","article-title":"Effectiveness of an intervention designed to optimize statins use: a primary prevention randomized clinical trial","volume":"15","author":"F\u00e0bregas","year":"2014","journal-title":"BMC Family Practice"},{"issue":"6","key":"10.1002\/14651858.CD006887.pub4-BIB0103|cit103","doi-asserted-by":"crossref","first-page":"e134","DOI":"10.1371\/journal.pmed.0030134","article-title":"Rational prescribing in primary care (RaPP): a cluster randomized trial of a tailored intervention","volume":"3","author":"Fretheim","year":"2006","journal-title":"PLOS Medicine"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0104|cit104","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1186\/1472-6963-3-5","article-title":"Rational Prescribing in Primary Care (RaPP-trial). A randomised trial of a tailored intervention to improve prescribing of antihypertensive and cholesterol-lowering drugs in general practice [ISRCTN48751230]","volume":"3","author":"Fretheim","year":"2003","journal-title":"BMC Health Services Research"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0105|cit105","doi-asserted-by":"crossref","first-page":"35","DOI":"10.2174\/1874192401509010035","article-title":"Cardiovascular risk assessment and effects on behavior in Switzerland: the Swiss Heart Foundation HerzCheck(R)\/Cardio-Test(R)","volume":"9","author":"Freund","year":"2015","journal-title":"Open Cardiovascular Medicine Journal"},{"issue":"5","key":"10.1002\/14651858.CD006887.pub4-BIB0106|cit106","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1089\/pop.2009.0003","article-title":"Impact of decision support in electronic medical records on lipid management in primary care","volume":"12","author":"Gill","year":"2009","journal-title":"Population Health Management"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0107|cit107","first-page":"498","article-title":"Effectiveness of an intervention to improve quality care in reducing cardiovascular risk in hypertensive patients","volume":"37","author":"Gomez-Marcos","year":"2006","journal-title":"Atencion Primaria"},{"issue":"4","key":"10.1002\/14651858.CD006887.pub4-BIB0108|cit108","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1016\/j.amepre.2013.11.009","article-title":"e-Care for heart wellness: a feasibility trial to decrease blood pressure and cardiovascular risk","volume":"46","author":"Green","year":"2014","journal-title":"American Journal of Preventive Medicine"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0109|cit109","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1186\/1472-6963-13-76","article-title":"Impact of effectiveness information format on patient choice of therapy and satisfaction with decisions about chronic disease medication: the Influence of intervention Methodologies on Patient Choice of Therapy (IMPACT) cluster-randomised trial in general practice","volume":"13","author":"Harmsen","year":"2013","journal-title":"BMC Health Services Research"},{"issue":"621","key":"10.1002\/14651858.CD006887.pub4-BIB0110|cit110","doi-asserted-by":"crossref","first-page":"e199","DOI":"10.3399\/bjgp14X677824","article-title":"Communicating risk using absolute risk reduction or prolongation of life formats: cluster-randomised trial in general practice","volume":"64","author":"Harmsen","year":"2014","journal-title":"The British Journal of General Practice"},{"issue":"19","key":"10.1002\/14651858.CD006887.pub4-BIB0111|cit111","doi-asserted-by":"crossref","first-page":"1736","DOI":"10.1001\/archinternmed.2011.471","article-title":"Shared electronic vascular risk decision support in primary care: Computerization of Medical Practices for the Enhancement of Therapeutic Effectiveness (COMPETE III) randomized trial","volume":"171","author":"Holbrook","year":"2011","journal-title":"Archives of Internal Medicine"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0112|cit112","first-page":"240","article-title":"Improved effectiveness in the management of cardiovascular risk among type 2 diabetic patients in primary health care","volume":"41","author":"Hormigo-Pozo","year":"2009","journal-title":"Atencion Primaria"},{"issue":"1","key":"10.1002\/14651858.CD006887.pub4-BIB0113|cit113","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1186\/1745-6215-14-433","article-title":"Effectiveness of a tailored intervention to improve cardiovascular risk management in primary care: study protocol for a randomised controlled trial","volume":"14","author":"Huntink","year":"2013","journal-title":"Trials"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0114|cit114","doi-asserted-by":"crossref","first-page":"1689","DOI":"10.2337\/dc10-2121","article-title":"Effect of nurse case management compared with usual care on controlling cardiovascular risk factors in patients with diabetes: a randomized controlled trial","volume":"34","author":"Ishani","year":"2011","journal-title":"Diabetes Care"},{"issue":"4","key":"10.1002\/14651858.CD006887.pub4-BIB0115|cit115","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1017\/S0266462311000341","article-title":"Willingness to pay for a cardiovascular prevention program in highly educated adults: a randomized controlled trial","volume":"27","author":"Jacobs","year":"2011","journal-title":"International Journal of Technology Assessment in Health Care"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0116|cit116","first-page":"12","article-title":"EUROACTION: a family-based preventive cardiology programme in primary care","volume":"4","author":"Jennings","year":"2006","journal-title":"Practical Cardiovascular Risk Management"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0117|cit117","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1177\/0272989X09333120","article-title":"Should clinicians deliver decision aids? Further exploration of the statin choice randomized trial results","volume":"29","author":"Jones","year":"2009","journal-title":"Medical Decision Making"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0118|cit118","doi-asserted-by":"crossref","first-page":"d442","DOI":"10.1136\/bmj.d442","article-title":"Improving cardiovascular health at population level: 39 community cluster randomised trial of Cardiovascular Health Awareness Program (CHAP)","volume":"342","author":"Kaczorowski","year":"2011","journal-title":"BMJ"},{"issue":"6","key":"10.1002\/14651858.CD006887.pub4-BIB0119|cit119","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1016\/j.ypmed.2008.02.005","article-title":"Cardiovascular Health Awareness Program (CHAP): a community cluster-randomised trial among elderly Canadians","volume":"46","author":"Kaczorowski","year":"2008","journal-title":"Preventive Medicine"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0120|cit120","first-page":"e474","article-title":"Improving cardiovascular health at the population level: a 39 community cluster randomized trial of the Cardiovascular Health Awareness Program (C-CHAP)","volume":"41","author":"Kaczorowski","year":"2010","journal-title":"Stroke"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0121|cit121","first-page":"291","article-title":"Individualised multifactorial lifestyle intervention trial for high-risk cardiovascular patients in primary care","volume":"51","author":"Ketola","year":"2001","journal-title":"British Journal of General Practice"},{"issue":"7","key":"10.1002\/14651858.CD006887.pub4-BIB0122|cit122","doi-asserted-by":"crossref","first-page":"1144","DOI":"10.1001\/jamainternmed.2014.1984","article-title":"A comparison of live counseling with a web-based lifestyle and medication intervention to reduce coronary heart disease risk: a randomized clinical trial","volume":"174","author":"Keyserling","year":"2014","journal-title":"JAMA Internal Medicine"},{"issue":"2","key":"10.1002\/14651858.CD006887.pub4-BIB0123|cit123","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1016\/j.cct.2013.07.013","article-title":"Designing and implementing a comparative effectiveness study of two strategies for delivering high quality CHD prevention: methods and participant characteristics for the Heart to Health study","volume":"36","author":"Sheridan","year":"2013","journal-title":"Contemporary Clinical Trials"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0124|cit124","first-page":"S13","article-title":"A randomized trial of a web-based versus counselor based intervention to reduce CHD risk","volume":"28","author":"Sheridan","year":"2013","journal-title":"Journal of General Internal Medicine"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0125|cit125","doi-asserted-by":"crossref","first-page":"A16508","DOI":"10.1161\/circ.132.suppl_3.16508","article-title":"Effect of disclosure of genetic risk for coronary heart disease on information seeking and information sharing in a randomized clinical trial (from the MI-GENES Investigators)","volume":"132","author":"Brown","year":"2015","journal-title":"Circulation"},{"issue":"12","key":"10.1002\/14651858.CD006887.pub4-BIB0126|cit126","doi-asserted-by":"crossref","first-page":"1181","DOI":"10.1161\/CIRCULATIONAHA.115.020109","article-title":"Incorporating a genetic risk score into coronary heart disease risk estimates: effect on low-density lipoprotein cholesterol levels (the MI-GENES Clinical Trial)","volume":"133","author":"Kullo","year":"2016","journal-title":"Circulation"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0127|cit127","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1186\/s12920-015-0122-0","article-title":"Design of a randomized controlled trial of disclosing genomic risk of coronary heart disease: the Myocardial Infarction Genes (MI-GENES) study","volume":"8","author":"Kullo","year":"2015","journal-title":"BMC Medical Genomics"},{"issue":"2","key":"10.1002\/14651858.CD006887.pub4-BIB0128|cit128","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1111\/cge.12577","article-title":"Disclosing genetic risk for coronary heart disease: effects on perceived personal control and genetic counseling satisfaction","volume":"89","author":"Robinson","year":"2016","journal-title":"Clinical Genetics"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0129|cit129","doi-asserted-by":"crossref","first-page":"A20188","DOI":"10.1161\/circ.130.suppl_2.20188","article-title":"The effect of disclosing genetic risk for coronary heart disease on perceived personal control and genetic counseling satisfaction: the MI-genes study","volume":"130","author":"Robinson","year":"2014","journal-title":"Circulation"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0130|cit130","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1186\/1471-2458-12-200","article-title":"Effectiveness of a web-based health risk assessment with individually-tailored feedback on lifestyle behaviour: study protocol","volume":"12","author":"Laan","year":"2012","journal-title":"BMC Public Health"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0131|cit131","doi-asserted-by":"crossref","first-page":"909","DOI":"10.1592\/phco.24.9.909.36104","article-title":"Development and preliminary testing of a patient decision aid to assist pharmaceutical care in the prevention of cardiovascular disease","volume":"24","author":"Lalonde","year":"2004","journal-title":"Pharmacotherapy"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0132|cit132","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1211\/ijpp.14.1.0007","article-title":"Evaluation of a decision aid and a personal risk profile in community pharmacy for patients considering options to improve cardiovascular health: the OPTIONS pilot study","volume":"14","author":"Lalonde","year":"2006","journal-title":"International Journal of Pharmacy Practice"},{"issue":"6","key":"10.1002\/14651858.CD006887.pub4-BIB0133|cit133","doi-asserted-by":"crossref","first-page":"650","DOI":"10.1177\/1403494807090165","article-title":"Health tests and health consultations reduced cardiovascular risk without psychological strain, increased healthcare utilization or increased costs. An overview of the results from a 5-year randomized trial in primary care. The Ebeltoft Health Promotion Project (EHPP)","volume":"36","author":"Lauritzen","year":"2008","journal-title":"Scandinavian Journal of Public Health"},{"issue":"1","key":"10.1002\/14651858.CD006887.pub4-BIB0134|cit134","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1186\/1748-5908-6-110","article-title":"Improved delivery of cardiovascular care (IDOCC) through outreach facilitation: study protocol and implementation details of a cluster randomized controlled trial in primary care","volume":"6","author":"Liddy","year":"2011","journal-title":"Implementation Science"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0135|cit135","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1186\/s13012-015-0341-y","article-title":"A real-world stepped wedge cluster randomized trial of practice facilitation to improve cardiovascular care","volume":"10","author":"Liddy","year":"2015","journal-title":"Implementation Science"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0136|cit136","doi-asserted-by":"crossref","first-page":"1105","DOI":"10.1136\/bmj.310.6987.1105","article-title":"The impact of health care advice given in primary care on cardiovascular risk","volume":"310","author":"Lindholm","year":"1995","journal-title":"BMJ"},{"issue":"21","key":"10.1002\/14651858.CD006887.pub4-BIB0137|cit137","doi-asserted-by":"crossref","first-page":"1988","DOI":"10.1001\/archinternmed.2009.381","article-title":"Case management to reduce risk of cardiovascular disease in a county health care system","volume":"169","author":"Ma","year":"2009","journal-title":"Archives of Internal Medicine"},{"issue":"6","key":"10.1002\/14651858.CD006887.pub4-BIB0138|cit138","doi-asserted-by":"crossref","first-page":"412","DOI":"10.2471\/BLT.08.062364","article-title":"Cardiovascular risk management and its impact on hypertension control in primary care in low-resource settings: a cluster-randomized trial","volume":"88","author":"Mendis","year":"2010","journal-title":"Bulletin of the World Health Organization"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0139|cit139","first-page":"30","article-title":"A primary care cardiovascular risk reduction clinic in Canada was more effective and no more expensive than usual on-demand primary care--a randomised controlled trial","volume":"18","author":"Mills","year":"2010","journal-title":"Health & Social Care in the Community"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0140|cit140","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1186\/s12875-015-0274-1","article-title":"From hypertension control to global cardiovascular risk management: an educational intervention in a cluster-randomised controlled trial","volume":"16","author":"Mortsiefer","year":"2015","journal-title":"BMC Family Practice"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0141|cit141","unstructured":"Personalized cardiovascular risk information to initiate and maintain health behavior changes (FIMDM_CVD) clinicaltrials.gov\/ct2\/show\/NCT01134458"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0142|cit142","unstructured":"The Alberta vascular risk reduction community pharmacy project: RxEACH (RxEACH) clinicaltrials.gov\/ct2\/show\/NCT01979471"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0143|cit143","first-page":"S81","article-title":"The efficacy of integration in clinical practice of electronic version of SCORE in treating hypertensive patients","volume":"18","author":"Nebieridze","year":"2011","journal-title":"European Journal of Cardiovascular Prevention and Rehabilitation"},{"issue":"1","key":"10.1002\/14651858.CD006887.pub4-BIB0144|cit144","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1046\/j.1369-6513.2002.00148.x","article-title":"Using disease risk estimates to guide risk factor interventions: field test of a patient workbook for self-assessing coronary risk","volume":"5","author":"Paterson","year":"2002","journal-title":"Health Expectations"},{"issue":"1","key":"10.1002\/14651858.CD006887.pub4-BIB0145|cit145","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1111\/j.1520-037X.2004.2417.x","article-title":"Heart to Heart: a computerized decision aid for assessment of coronary heart disease risk and the impact of risk-reduction interventions for primary prevention","volume":"7","author":"Pignone","year":"2004","journal-title":"Preventive Cardiology"},{"issue":"4","key":"10.1002\/14651858.CD006887.pub4-BIB0146|cit146","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1016\/j.ahj.2010.12.021","article-title":"The effectiveness of personalized coronary heart disease and stroke risk communication","volume":"161","author":"Powers","year":"2011","journal-title":"American Heart Journal"},{"issue":"4","key":"10.1002\/14651858.CD006887.pub4-BIB0147|cit147","doi-asserted-by":"crossref","first-page":"253","DOI":"10.7326\/0003-4819-156-4-201202210-00002","article-title":"Effect of adding systematic family history enquiry to cardiovascular disease risk assessment in primary care: a matched-pair, cluster randomized trial","volume":"156","author":"Qureshi","year":"2012","journal-title":"Annals of Internal Medicine"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0148|cit148","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1097\/00043798-199504000-00012","article-title":"Cardiovascular risk reduction: a randomized trial of two health promotion strategies for lowering risk in a community with low socioeconomic status","volume":"2","author":"Reid","year":"1995","journal-title":"Journal of Cardiovascular Risk"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0149|cit149","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1186\/1471-2458-10-449","article-title":"EDUCORE project: a clinical trial, randomised by clusters, to assess the effect of a visual learning method on blood pressure control in the primary healthcare setting","volume":"10","author":"Rodriguez-Salceda","year":"2010","journal-title":"BMC Public Health"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0150|cit150","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1186\/1471-2296-13-97","article-title":"The impact of a disease management program (COACH) on the attainment of better cardiovascular risk control in dyslipidaemic patients at primary care centres (the DISSEMINATE Study): a randomised controlled trial","volume":"13","author":"Selvaraj","year":"2012","journal-title":"BMC Family Practice"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0151|cit151","first-page":"S268","article-title":"Patients' choices for lifestyle change versus medication use to reduce elevated CVD risk","volume":"27","author":"Sheridan","year":"2012","journal-title":"Journal of General Internal Medicine"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0152|cit152","first-page":"S405","article-title":"Impact of providing people with type 2 diabetes with their actual risk for five diabetes complications: A pilot study","volume":"54","author":"Skinner","year":"2011","journal-title":"Diabetologia"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0153|cit153","doi-asserted-by":"crossref","first-page":"747","DOI":"10.4065\/83.7.747","article-title":"Chronic care model and shared care in diabetes: randomized trial of an electronic decision support system","volume":"83","author":"Smith","year":"2008","journal-title":"Mayo Clinic Proceedings"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0154|cit154","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1097\/HJR.0b013e328337ccd3","article-title":"Evaluation of a cardiovascular disease risk assessment tool for the promotion of healthier lifestyles","volume":"17","author":"Soureti","year":"2010","journal-title":"European Journal of Cardiovascular Prevention and Rehabilitation"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0155|cit155","doi-asserted-by":"crossref","first-page":"e7156","DOI":"10.1136\/bmj.e7156","article-title":"Effect of intensive structured care on individual blood pressure targets in primary care: multicentre randomised controlled trial","volume":"345","author":"Stewart","year":"2012","journal-title":"BMJ"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0156|cit156","first-page":"679","article-title":"A national, multicentre, randomized controlled trial of the efficacy of structured care algorithm in achieving individual blood pressure targets at 26 weeks in primary care","volume":"33","author":"Stewart","year":"2012","journal-title":"European Heart Journal"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0157|cit157","first-page":"811","article-title":"Reduced blood pressure and risk of future cardiovascular disease from structured care algorithm in primary care patients with persistent hypertension: a multicentere randomized controlled trial","volume":"33","author":"Stewart","year":"2012","journal-title":"European Heart Journal"},{"issue":"5","key":"10.1002\/14651858.CD006887.pub4-BIB0158|cit158","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1177\/174182670100800508","article-title":"A new method for CHD prediction and prevention based on regional risk scores and randomized clinical trials; PRECARD and the Copenhagen Risk Score","volume":"8","author":"Thomsen","year":"2001","journal-title":"Journal of Cardiovascular Risk"},{"issue":"4","key":"10.1002\/14651858.CD006887.pub4-BIB0159|cit159","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1071\/PY11091","article-title":"Sustaining cardiovascular absolute risk management in Australian general practice","volume":"18","author":"Vaidya","year":"2012","journal-title":"Australian Journal of Primary Health"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0160|cit160","doi-asserted-by":"crossref","first-page":"e272","DOI":"10.1016\/j.atherosclerosis.2014.05.814","article-title":"Self-reported adherence to cardiovascular risk reduction intervention of patients with rheumatoid arthritis: results of the Francis study","volume":"235","author":"Van Breukelen-van der Stoep","year":"2014","journal-title":"Atherosclerosis"},{"issue":"5","key":"10.1002\/14651858.CD006887.pub4-BIB0161|cit161","doi-asserted-by":"crossref","first-page":"544","DOI":"10.1177\/2047487315591441","article-title":"Personalized prevention approach with use of a web-based cardiovascular risk assessment with tailored lifestyle follow-up in primary care practice - a pilot study","volume":"23","author":"Van den Brekel-Dijkstra","year":"2016","journal-title":"European Journal of Preventive Cardiology"},{"issue":"6","key":"10.1002\/14651858.CD006887.pub4-BIB0162|cit162","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1016\/j.ypmed.2011.08.031","article-title":"Effects of a brief cardiovascular prevention program by a health advisor in primary care; the 'Hartslag Limburg' project, a cluster randomized trial","volume":"53","author":"Van Limpt","year":"2011","journal-title":"Preventive Medicine"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0163|cit163","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1186\/1472-6947-10-41","article-title":"The effect of different cardiovascular risk presentation formats on intentions, understanding and emotional affect: a randomised controlled trial using a web-based risk formatter (protocol)","volume":"10","author":"Waldron","year":"2010","journal-title":"BMC Medical Informatics and Decision Making"},{"issue":"10","key":"10.1002\/14651858.CD006887.pub4-BIB0164|cit164","doi-asserted-by":"crossref","first-page":"1076","DOI":"10.1001\/archinte.167.10.1076","article-title":"Helping patients with type 2 diabetes mellitus make treatment decisions: statin choice randomized trial","volume":"167","author":"Weymiller","year":"2007","journal-title":"Archives of Internal Medicine"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0165|cit165","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1016\/j.atherosclerosis.2013.09.029","article-title":"Pilot study to validate a computer-based clinical decision support system for dyslipidemia treatment (HTE-DLP)","volume":"231","author":"Zamora","year":"2013","journal-title":"Atherosclerosis"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0166|cit166","first-page":"285","article-title":"A clinical decision support system can improves the quality of lipid-lowering therapy in coronary patients","volume":"36","author":"Zamora","year":"2015","journal-title":"European Heart Journal"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0167|cit167","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1186\/1471-2458-13-219","article-title":"Evaluation of a community intervention program in Japan using Framingham risk score and estimated 10-year coronary heart disease risk as outcome variables: a non-randomized controlled trial","volume":"13","author":"Zhu","year":"2013","journal-title":"BMC Public Health"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0168|cit168","first-page":"194","article-title":"Adding value to the experience of attending a diabetes clinic appointment: Provision of personalised 10 year cardiovascular disease (CVD) risk estimates","volume":"30","author":"Adamson","year":"2013","journal-title":"Diabetic Medicine"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0169|cit169","unstructured":"Gryn S Har B Dresser G Evaluation of the effect of cardiovascular risk assessment on treatment compliance in hypertension Journal of Clinical Hypertension 2012 14"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0170|cit170","first-page":"A88","article-title":"Communicating cardiovascular risk to Latinos with type 2 diabetes using a Spanish language-based multimedia program","volume":"61","author":"Roach","year":"2012","journal-title":"Diabetes"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0171|cit171","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1186\/1471-2296-15-90","article-title":"Design of the INTEGRATE study: effectiveness and cost-effectiveness of a cardiometabolic risk assessment and treatment program integrated in primary care","volume":"15","author":"Badenbroek","year":"2014","journal-title":"BMC Family Practice"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0172|cit172","first-page":"985","article-title":"Design and recruitment of the ROBINSCA trial: Screening for cardiovascular disease","volume":"36","author":"De Koning","year":"2015","journal-title":"European Heart Journal"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0173|cit173","first-page":"S21","article-title":"A randomized controlled trial measuring the effectiveness of screening for cardiovascular disease using classic risk assessment and coronary artery calcium: The ROBINSCA study","volume":"21","author":"Ijkema","year":"2014","journal-title":"European Journal of Preventive Cardiology"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0174|cit174","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1186\/1745-6215-15-341","article-title":"Effectiveness of the population-based Check your health preventive programme conducted in primary care with 4 years follow-up [the CORE trial]: study protocol for a randomised controlled trial","volume":"15","author":"Maindal","year":"2014","journal-title":"Trials"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0175|cit175","unstructured":"Risk assessment and treat compliance in hypertension education trial (RATCHET) clinicaltrials.gov\/ct2\/show\/NCT00694239"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0176|cit176","unstructured":"Effect of patient education on compliance and cardiovascular risk parameters (FAILAKA) clinicaltrials.gov\/ct2\/show\/NCT02096887"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0177|cit177","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1186\/1748-5908-9-73","article-title":"A cluster-randomized trial of task shifting and blood pressure control in Ghana: study protocol","volume":"9","author":"Ogedegbe","year":"2014","journal-title":"Implementation Science"},{"issue":"1","key":"10.1002\/14651858.CD006887.pub4-BIB0178|cit178","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1186\/1748-5908-8-137","article-title":"A multifaceted strategy using mobile technology to assist rural primary healthcare doctors and frontline health workers in cardiovascular disease risk management: protocol for the SMARTHealth India cluster randomised controlled trial","volume":"8","author":"Praveen","year":"2013","journal-title":"Implementation Science"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0179|cit179","doi-asserted-by":"crossref","first-page":"e004523","DOI":"10.1136\/bmjopen-2013-004523","article-title":"A randomised controlled trial of a consumer-focused e-health strategy for cardiovascular risk management in primary care: the Consumer Navigation of Electronic Cardiovascular Tools (CONNECT) study protocol","volume":"4","author":"Redfern","year":"2014","journal-title":"BMJ Open"},{"issue":"2","key":"10.1002\/14651858.CD006887.pub4-BIB0180|cit180","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1001\/jama.2015.6681","article-title":"Paying for Prevention: A Novel Test of Medicare Value-Based Payment for Cardiovasculr Risk Reduction","volume":"314","author":"Sanghavi","year":"2015","journal-title":"JAMA"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0181|cit181","doi-asserted-by":"crossref","first-page":"868","DOI":"10.1186\/s12889-015-2192-5","article-title":"Information and Risk Modification Trial (INFORM): design of a randomised controlled trial of communicating different types of information about coronary heart disease risk, alongside lifestyle advice, to achieve change in health-related behaviour","volume":"15","author":"Silarova","year":"2015","journal-title":"BMC Public Health"},{"issue":"1 Pt 2","key":"10.1002\/14651858.CD006887.pub4-BIB0182|cit182","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/0002-8703(91)90861-B","article-title":"Cardiovascular disease risk profiles","volume":"121","author":"Anderson","year":"1991","journal-title":"American Heart Journal"},{"issue":"2","key":"10.1002\/14651858.CD006887.pub4-BIB0183|cit183","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/j.cjca.2012.11.032","article-title":"2012 update of the Canadian Cardiovascular Society guidelines for the diagnosis and treatment of dyslipidemia for the prevention of cardiovascular disease in the adult","volume":"29","author":"Anderson","year":"2013","journal-title":"Canadian Journal of Cardiology"},{"issue":"3","key":"10.1002\/14651858.CD006887.pub4-BIB0184|cit184","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1161\/hc0302.102575","article-title":"Simple scoring scheme for calculating the risk of acute coronary events based on the 10-year follow-up of the prospective cardiovascular M\u00fcnster (PROCAM) study","volume":"105","author":"Assmann","year":"2002","journal-title":"Circulation"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0185|cit185","doi-asserted-by":"crossref","unstructured":"Beswick AD Brindle P Fahey T Ebrahim S A systematic review of risk scoring methods and clinical decision aids used in the primary prevention of coronary heart disease (Supplement) London (UK): Royal College of General Practitioners; May 2008. NICE Clinical Guidelines No. 67S 21834196","DOI":"10.1002\/14651858.CD006887"},{"issue":"5","key":"10.1002\/14651858.CD006887.pub4-BIB0186|cit186","first-page":"957","article-title":"27th Bethesda Conference. Matching the intensity of risk factor management with the hazard for coronary disease events. September 14-15, 1995","volume":"27","year":"1996","journal-title":"Journal of the American College of Cardiology"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0187|cit187","volume-title":"The Global Economic Burden of Non-communicable Diseases","author":"Bloom","year":"2011"},{"issue":"9943","key":"10.1002\/14651858.CD006887.pub4-BIB0188|cit188","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1016\/S0140-6736(14)61212-5","article-title":"Blood pressure-lowering treatment based on cardiovascular risk: a meta-analysis of individual patient data","volume":"384","author":"Sundstr\u00f6m","year":"2014","journal-title":"Lancet"},{"issue":"12","key":"10.1002\/14651858.CD006887.pub4-BIB0189|cit189","doi-asserted-by":"crossref","first-page":"1752","DOI":"10.1136\/hrt.2006.087932","article-title":"Accuracy and impact of risk assessment in the primary prevention of cardiovascular disease: a systematic review","volume":"92","author":"Brindle","year":"2006","journal-title":"Heart"},{"issue":"11","key":"10.1002\/14651858.CD006887.pub4-BIB0190|cit190","doi-asserted-by":"crossref","first-page":"987","DOI":"10.1016\/S0195-668X(03)00114-3","article-title":"Estimation of ten-year risk of fatal cardiovascular disease in Europe: the SCORE project","volume":"24","author":"Conroy","year":"2003","journal-title":"European Heart Journal"},{"issue":"9841","key":"10.1002\/14651858.CD006887.pub4-BIB0191|cit191","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1016\/S0140-6736(12)60367-5","article-title":"The effects of lowering LDL cholesterol with statin therapy in people at low risk of vascular disease: meta-analysis of individual data from 27 randomised trials","volume":"380","author":"Mihaylova","year":"2012","journal-title":"Lancet"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0192|cit192","doi-asserted-by":"crossref","first-page":"i2416","DOI":"10.1136\/bmj.i2416","article-title":"Prediction models for cardiovascular disease risk in the general population: systematic review","volume":"353","author":"Damen","year":"2016","journal-title":"BMJ"},{"issue":"25 Suppl 2","key":"10.1002\/14651858.CD006887.pub4-BIB0193|cit193","first-page":"S49","article-title":"2013 ACC\/AHA guideline on the assessment of cardiovascular risk: a report of the American College of Cardiology\/American Heart Association task force on practice guidelines","volume":"129","author":"Lloyd-Jones","year":"2014","journal-title":"Circulation"},{"issue":"6985","key":"10.1002\/14651858.CD006887.pub4-BIB0194|cit194","doi-asserted-by":"crossref","first-page":"975","DOI":"10.1136\/bmj.310.6985.975","article-title":"Do doctors accurately assess coronary risk in their patients? Preliminary results of the coronary health assessment study","volume":"310","author":"Grover","year":"1995","journal-title":"BMJ"},{"issue":"7650","key":"10.1002\/14651858.CD006887.pub4-BIB0195|cit195","doi-asserted-by":"crossref","first-page":"924","DOI":"10.1136\/bmj.39489.470347.AD","article-title":"GRADE: an emerging consensus on rating quality of evidence and strength of recommendations","volume":"336","author":"Guyatt","year":"2008","journal-title":"BMJ"},{"issue":"5","key":"10.1002\/14651858.CD006887.pub4-BIB0196|cit196","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1016\/S2213-8587(15)00081-9","article-title":"A novel risk score to predict cardiovascular disease risk in national populations (Globorisk): a pooled analysis of prospective cohorts and health examination surveys","volume":"3","author":"Hajifathalian","year":"2015","journal-title":"Lancet Diabetes & Endocrinology"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0197|cit197","unstructured":"Higgins JPT Cochrane Handbook for Systematic Reviews of Interventions Version 5.1 [updated March 2011]. The Cochrane Collaboration, 2011 Available from www.cochrane-handbook.org"},{"issue":"7611","key":"10.1002\/14651858.CD006887.pub4-BIB0198|cit198","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1136\/bmj.39261.471806.55","article-title":"Derivation and validation of QRISK, a new cardiovascular disease risk score for the United Kingdom: prospective open cohort study","volume":"335","author":"Hippisley-Cox","year":"2007","journal-title":"BMJ"},{"issue":"7659","key":"10.1002\/14651858.CD006887.pub4-BIB0199|cit199","doi-asserted-by":"crossref","first-page":"1475","DOI":"10.1136\/bmj.39609.449676.25","article-title":"Predicting cardiovascular risk in England and Wales: prospective derivation and validation of QRISK2","volume":"336","author":"Hippisley-Cox","year":"2008","journal-title":"BMJ"},{"issue":"9457","key":"10.1002\/14651858.CD006887.pub4-BIB0200|cit200","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1016\/S0140-6736(05)70240-3","article-title":"Treatment with drugs to lower blood pressure and blood cholesterol based on an individual's absolute cardiovascular risk","volume":"365","author":"Jackson","year":"2005","journal-title":"Lancet"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0201|cit201","unstructured":"Lefebvre C Manheimer E Glanville J Chapter 6: Searching for studies. In: Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 [updated March 2011]. The Cochrane Collaboration, 2011 Available from www.cochrane-handbook.org"},{"issue":"2","key":"10.1002\/14651858.CD006887.pub4-BIB0202|cit202","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1093\/fampra\/11.2.117","article-title":"Assessment of coronary heart disease risk, I. A postal inquiry among primary care physicians","volume":"11","author":"Meland","year":"1994","journal-title":"Family Practice"},{"issue":"9859","key":"10.1002\/14651858.CD006887.pub4-BIB0203|cit203","doi-asserted-by":"crossref","first-page":"2197","DOI":"10.1016\/S0140-6736(12)61689-4","article-title":"Disability-adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010","volume":"380","author":"Murray","year":"2012","journal-title":"Lancet"},{"issue":"9963","key":"10.1002\/14651858.CD006887.pub4-BIB0204|cit204","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/S0140-6736(14)61682-2","article-title":"Global, regional, and national age-sex specific all-cause and cause-specific mortality for 240 causes of death, 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013","volume":"385","author":"Naghavi","year":"2015","journal-title":"Lancet"},{"issue":"25","key":"10.1002\/14651858.CD006887.pub4-BIB0205|cit205","doi-asserted-by":"crossref","first-page":"3143","DOI":"10.1161\/circ.106.25.3143","article-title":"Third report of the National Cholesterol Education Program (NCEP) expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (Adult Treatment Panel III) final report","volume":"106","author":"National Cholesterol Education Program (NCEP) expert panel on detection","year":"2002","journal-title":"Circulation"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0206|cit206","unstructured":"National Institute for Health and Care Excellence (NICE) Lipid modification: Cardiovascular risk assessment and the modification of blood lipids for primary and secondary prevention of cardiovascular disease www.nice.org.uk\/guidance\/cg181"},{"issue":"9735","key":"10.1002\/14651858.CD006887.pub4-BIB0207|cit207","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1016\/S0140-6736(10)60834-3","article-title":"Risk factors for ischaemic and intracerebral haemorrhagic stroke in 22 countries (the INTERSTROKE study): a case-control study","volume":"376","author":"O'Donnell","year":"2010","journal-title":"Lancet"},{"issue":"29","key":"10.1002\/14651858.CD006887.pub4-BIB0208|cit208","doi-asserted-by":"crossref","first-page":"2315","DOI":"10.1093\/eurheartj\/ehw106","article-title":"2016 European guidelines on cardiovascular disease prevention in clinical practice: the sixth joint task force of the European Society of Cardiology and other societies on cardiovascular disease prevention in clinical practice (constituted by representatives of 10 societies and by invited experts)","volume":"37","author":"Piepoli","year":"2016","journal-title":"European Heart Journal"},{"issue":"1","key":"10.1002\/14651858.CD006887.pub4-BIB0209|cit209","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1186\/1472-6963-3-13","article-title":"Physicians' ability to predict the risk of coronary heart disease","volume":"3","author":"Pignone","year":"2003","journal-title":"BMC Health Services Research"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0210|cit210","unstructured":"Review Manager (RevMan) Nordic Cochrane Centre, The Cochrane Collaboration 2014"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0211|cit211","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1186\/1472-6963-8-60","article-title":"Does the routine use of global coronary heart disease risk scores translate into clinical benefits or harms? A systematic review of the literature","volume":"8","author":"Sheridan","year":"2008","journal-title":"BMC Health Services Research"},{"issue":"3","key":"10.1002\/14651858.CD006887.pub4-BIB0212|cit212","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1001\/archinternmed.2009.516","article-title":"The effect of giving global coronary risk information to adults: a systematic review","volume":"170","author":"Sheridan","year":"2010","journal-title":"Archives of Internal Medicine"},{"issue":"25","key":"10.1002\/14651858.CD006887.pub4-BIB0213|cit213","doi-asserted-by":"crossref","first-page":"3112","DOI":"10.1161\/01.CIR.0000133427.35111.67","article-title":"Principles for national and regional guidelines on cardiovascular disease prevention: a scientific statement from the World Heart and Stroke Forum","volume":"109","author":"Jackson","year":"2004","journal-title":"Circulation"},{"issue":"25 Suppl 2","key":"10.1002\/14651858.CD006887.pub4-BIB0214|cit214","first-page":"S1","article-title":"2013 ACC\/AHA guideline on the treatment of blood cholesterol to reduce atherosclerotic cardiovascular risk in adults: a report of the American College of Cardiology\/American Heart Association Task Force on Practice Guidelines","volume":"129","author":"Stone","year":"2014","journal-title":"Circulation"},{"issue":"10","key":"10.1002\/14651858.CD006887.pub4-BIB0215|cit215","doi-asserted-by":"crossref","first-page":"e008717","DOI":"10.1136\/bmjopen-2015-008717","article-title":"Impact of provision of cardiovascular disease risk estimates to healthcare professionals and patients: a systematic review","volume":"5","author":"Usher-Smith","year":"2015","journal-title":"BMJ Open"},{"issue":"5","key":"10.1002\/14651858.CD006887.pub4-BIB0216|cit216","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1097\/HCO.0b013e32830b35f6","article-title":"Primary care patients' recognition of their own risk for cardiovascular disease: implications for risk communication in practice","volume":"23","author":"Van der Weijden","year":"2008","journal-title":"Current Opinion in Cardiology"},{"key":"10.1002\/14651858.CD006887.pub4-BIB0217|cit217","volume-title":"Prevention of Cardiovascular Disease: Guidelines for Assessment and Management of Total Cardiovascular Risk","author":"World Health Organization","year":"2007"},{"issue":"8","key":"10.1002\/14651858.CD006887.pub4-BIB0218|cit218","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1258\/jrsm.2012.110193","article-title":"Primary prevention of cardiovascular disease using validated risk scores: a systematic review","volume":"105","author":"Willis","year":"2012","journal-title":"Journal of Royal Society of Medicine"},{"issue":"18","key":"10.1002\/14651858.CD006887.pub4-BIB0219|cit219","doi-asserted-by":"crossref","first-page":"1837","DOI":"10.1161\/01.CIR.97.18.1837","article-title":"Prediction of coronary heart disease using risk factor categories","volume":"97","author":"Wilson","year":"1998","journal-title":"Circulation"},{"issue":"1","key":"10.1002\/14651858.CD006887.pub4-BIB0220|cit220","first-page":"41","article-title":"Developing optimal search strategies for detecting clinically sound treatment studies in EMBASE","volume":"94","author":"Wong","year":"2006","journal-title":"Journal of the Medical Library Association"},{"issue":"9438","key":"10.1002\/14651858.CD006887.pub4-BIB0221|cit221","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1016\/S0140-6736(04)17018-9","article-title":"Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the INTERHEART study): case-control study","volume":"364","author":"Yusuf","year":"2004","journal-title":"Lancet"}],"container-title":["Cochrane Database of Systematic Reviews"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full\/10.1002\/14651858.CD006887.pub4","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,9,27]],"date-time":"2024-09-27T13:24:10Z","timestamp":1727443450000},"score":1,"resource":{"primary":{"URL":"http:\/\/doi.wiley.com\/10.1002\/14651858.CD006887.pub4"}},"subtitle":[],"editor":[{"name":"Cochrane Heart Group","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2017,3,14]]},"references-count":221,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2021,6]]}},"URL":"https:\/\/doi.org\/10.1002\/14651858.cd006887.pub4","relation":{},"ISSN":["1465-1858"],"issn-type":[{"value":"1465-1858","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,3,14]]}}}