{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,4]],"date-time":"2026-03-04T02:50:48Z","timestamp":1772592648103,"version":"3.50.1"},"update-to":[{"DOI":"10.1002\/14651858.cd006915.pub2","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2015,9,18]],"date-time":"2015-09-18T00:00:00Z","timestamp":1442534400000}}],"reference-count":84,"publisher":"Wiley","issue":"9","content-domain":{"domain":["wiley.com","cochranelibrary.com"],"crossmark-restriction":true},"short-container-title":[],"DOI":"10.1002\/14651858.cd006915.pub3","type":"journal-article","created":{"date-parts":[[2015,9,18]],"date-time":"2015-09-18T15:00:17Z","timestamp":1442588417000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":31,"title":["Heliox inhalation therapy for bronchiolitis in infants"],"prefix":"10.1002","volume":"2015","author":[{"given":"Jean-Michel","family":"Liet","sequence":"first","affiliation":[{"name":"H\u00f4pital M\u00e8re-Enfant, CHU de Nantes; Pediatric Intensive Care Unit; 38 Boulevard Jean-Monnet Fa\u00efencerie Nantes France 44093"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thierry","family":"Ducruet","sequence":"additional","affiliation":[{"name":"CHU Sainte-Justine; Research Center; Montreal QC Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vineet","family":"Gupta","sequence":"additional","affiliation":[{"name":"Moses Cone Hospital; Pediatric Critical Care Medicine; 1200 N. Elm Street Greensboro NC USA 27401"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gilles","family":"Cambonie","sequence":"additional","affiliation":[{"name":"H\u00f4pital Arnaud de Villeneuve; Service de R\u00e9animation P\u00e9diatrique et N\u00e9onatale, P\u00e9diatrie II; 371 av du Doyen Gaston Giraud Montpellier CEDEX 5 France 34295"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,9,18]]},"reference":[{"issue":"3","key":"10.1002\/14651858.CD006915.pub3-BIB0001|cit1","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1378\/chest.129.3.676","article-title":"Clinical effects of heliox administration for acute bronchiolitis in young infants","volume":"129","author":"Cambonie","year":"2006","journal-title":"Chest"},{"issue":"4","key":"10.1002\/14651858.CD006915.pub3-BIB0002|cit2","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1542\/peds.2012-1317","article-title":"Heliox therapy in bronchiolitis: phase III multicenter double-blind randomized controlled trial","volume":"131","author":"Chowdhury","year":"2013","journal-title":"Pediatrics"},{"issue":"10","key":"10.1002\/14651858.CD006915.pub3-BIB0003|cit3","doi-asserted-by":"crossref","first-page":"1731","DOI":"10.1097\/00003246-199810000-00031","article-title":"Helium-oxygen improves clinical asthma scores in children with acute bronchiolitis","volume":"26","author":"Hollman","year":"1998","journal-title":"Critical Care Medicine"},{"issue":"12","key":"10.1002\/14651858.CD006915.pub3-BIB0004|cit4","doi-asserted-by":"crossref","first-page":"1115","DOI":"10.1001\/archpediatrics.2011.605","article-title":"Helium-oxygen therapy for infants with bronchiolitis: a randomized controlled trial","volume":"165","author":"Kim","year":"2011","journal-title":"Archives of Pediatrics and Adolescent Medicine"},{"issue":"3","key":"10.1002\/14651858.CD006915.pub3-BIB0005|cit5","doi-asserted-by":"crossref","first-page":"R71","DOI":"10.1186\/cc7880","article-title":"Heliox reduces respiratory system resistance in respiratory syncytial virus induced respiratory failure","volume":"13","author":"Kneyber","year":"2009","journal-title":"Critical Care"},{"issue":"6","key":"10.1002\/14651858.CD006915.pub3-BIB0006|cit6","doi-asserted-by":"crossref","first-page":"812","DOI":"10.1016\/j.jpeds.2005.07.015","article-title":"Noninvasive therapy with helium-oxygen for severe bronchiolitis","volume":"147","author":"Liet","year":"2005","journal-title":"Journal of Pediatrics"},{"issue":"5","key":"10.1002\/14651858.CD006915.pub3-BIB0007|cit7","doi-asserted-by":"crossref","first-page":"e1190","DOI":"10.1542\/peds.2007-1840","article-title":"Nasal continuous positive airway pressure with heliox versus air oxygen in infants with acute bronchiolitis: a crossover study","volume":"121","author":"Martin\u00f3n-Torres","year":"2008","journal-title":"Pediatrics"},{"issue":"3","key":"10.1002\/14651858.CD006915.pub3-BIB0008|cit8","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1097\/01.PCC.0000074267.11280.78","article-title":"Helium-oxygen therapy for pediatric acute severe asthma requiring mechanical ventilation","volume":"4","author":"Abd-Allah","year":"2003","journal-title":"Pediatric Critical Care Medicine"},{"issue":"2","key":"10.1002\/14651858.CD006915.pub3-BIB0009|cit9","doi-asserted-by":"crossref","first-page":"e333","DOI":"10.1542\/peds.2011-0532","article-title":"Nasal continuous positive airway pressure with heliox in preterm infants with respiratory distress syndrome","volume":"129","author":"Colnaghi","year":"2012","journal-title":"Pediatrics"},{"issue":"10","key":"10.1002\/14651858.CD006915.pub3-BIB0010|cit10","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1017\/S0265021507000695","article-title":"Combination of heliox and CPAP without a ventilator: bench test and clinical observations","volume":"24","author":"Dieperink","year":"2007","journal-title":"European Journal of Anaesthesiology"},{"issue":"3","key":"10.1002\/14651858.CD006915.pub3-BIB0011|cit11","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1007\/BF03006983","article-title":"Efficacy of helium-oxygen mixtures in the management of severe viral and post-intubation croup","volume":"26","author":"Duncan","year":"1979","journal-title":"Canadian Anaesthetists' Society Journal"},{"issue":"1","key":"10.1002\/14651858.CD006915.pub3-BIB0012|cit12","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1016\/S0022-3476(05)83506-1","article-title":"Helium-oxygen mixture in respiratory distress syndrome: a double-blind study","volume":"122","author":"Elleau","year":"1993","journal-title":"Journal of Pediatrics"},{"issue":"3","key":"10.1002\/14651858.CD006915.pub3-BIB0013|cit13","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1186\/cc692","article-title":"Helium-oxygen mixture does not improve gas exchange in mechanically ventilated children with bronchiolitis","volume":"4","author":"Gross","year":"2000","journal-title":"Critical Care"},{"issue":"9","key":"10.1002\/14651858.CD006915.pub3-BIB0014|cit14","doi-asserted-by":"crossref","first-page":"1512","DOI":"10.1097\/00005537-200109000-00004","article-title":"Use of helium-oxygen mixtures to relieve upper airway obstruction in a pediatric population","volume":"111","author":"Grosz","year":"2001","journal-title":"Laryngoscope"},{"issue":"9","key":"10.1002\/14651858.CD006915.pub3-BIB0015|cit15","first-page":"1038","article-title":"Heliox administration during high-frequency jet ventilation augments carbon dioxide clearance","volume":"49","author":"Gupta","year":"2004","journal-title":"Respiratory Care"},{"issue":"3","key":"10.1002\/14651858.CD006915.pub3-BIB0016|cit16","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1157\/13099685","article-title":"Efficacy of heliox therapy in respiratory insufficiency in infants and children","volume":"66","author":"Iglesias Fern\u00e1ndez","year":"2007","journal-title":"Anales de Pediatr\u00eda"},{"issue":"4","key":"10.1002\/14651858.CD006915.pub3-BIB0017|cit17","first-page":"145","article-title":"Inhalation of helium in the complex treatment of children with respiratory insufficiency","volume":"46","author":"Isakov","year":"1970","journal-title":"Khirurgiia"},{"issue":"10","key":"10.1002\/14651858.CD006915.pub3-BIB0018|cit18","doi-asserted-by":"crossref","first-page":"1676","DOI":"10.1007\/s00134-006-0348-6","article-title":"Mechanical ventilation with heliox decreases respiratory system resistance and facilitates CO2 removal in obstructive airway disease","volume":"32","author":"Kneyber","year":"2006","journal-title":"Intensive Care Medicine"},{"key":"10.1002\/14651858.CD006915.pub3-BIB0019|cit19","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1542\/peds.109.1.68","article-title":"Heliox therapy in infants with acute bronchiolitis","volume":"109","author":"Martinon-Torres","year":"2002","journal-title":"Pediatrics"},{"issue":"1","key":"10.1002\/14651858.CD006915.pub3-BIB0020|cit20","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1157\/13070183","article-title":"Noninvasive ventilation with heliox in an infant with acute respiratory distress syndrome","volume":"62","author":"Martin\u00f3n-Torres","year":"2005","journal-title":"Anales de Pediatr\u00eda"},{"issue":"8","key":"10.1002\/14651858.CD006915.pub3-BIB0021|cit21","doi-asserted-by":"crossref","first-page":"1458","DOI":"10.1016\/j.rmed.2005.11.026","article-title":"Nasal continuous positive airway pressure with heliox in infants with acute bronchiolitis","volume":"100","author":"Martin\u00f3n-Torres","year":"2006","journal-title":"Respiratory Medicine"},{"issue":"2","key":"10.1002\/14651858.CD006915.pub3-BIB0022|cit22","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1111\/j.1651-2227.2009.01529.x","article-title":"Helmet-delivered continuous positive airway pressure with heliox in respiratory syncytial virus bronchiolitis","volume":"99","author":"Mayordomo-Colunga","year":"2010","journal-title":"Acta Paediatrica"},{"issue":"Suppl 3","key":"10.1002\/14651858.CD006915.pub3-BIB0023|cit23","first-page":"A83","article-title":"Noninvasive ventilation for acute respiratory failure","volume":"12","author":"Montaguti","year":"2011","journal-title":"Pediatric Critical Care Medicine"},{"issue":"5","key":"10.1002\/14651858.CD006915.pub3-BIB0024|cit24","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1002\/(SICI)1099-0496(199611)22:5<322::AID-PPUL6>3.0.CO;2-M","article-title":"Heliox in respiratory failure secondary to bronchiolitis: a new therapy","volume":"22","author":"Paret","year":"1996","journal-title":"Pediatric Pulmonology"},{"issue":"1","key":"10.1002\/14651858.CD006915.pub3-BIB0025|cit25","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1097\/00006565-199702000-00010","article-title":"Heliox in children with airway obstruction","volume":"13","author":"Tobias","year":"1997","journal-title":"Pediatric Emergency Care"},{"issue":"5","key":"10.1002\/14651858.CD006915.pub3-BIB0026|cit26","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1046\/j.1460-9592.1999.00355.x","article-title":"High-frequency jet ventilation using a helium-oxygen mixture","volume":"9","author":"Tobias","year":"1999","journal-title":"Paediatric Anaesthesia"},{"issue":"1","key":"10.1002\/14651858.CD006915.pub3-BIB0027|cit27","doi-asserted-by":"crossref","first-page":"73","DOI":"10.2223\/JPED.36","article-title":"Helium-oxigen (Heliox) mixture in airway obstruction","volume":"76","author":"Ulh\u00f4a","year":"2000","journal-title":"Jornal de Pediatria"},{"issue":"9","key":"10.1002\/14651858.CD006915.pub3-BIB0028|cit28","doi-asserted-by":"crossref","first-page":"574","DOI":"10.1097\/01.pec.0000139738.08474.54","article-title":"Therapeutic benefits of helium-oxygen delivery to infants via nasal cannula","volume":"20","author":"Williams","year":"2004","journal-title":"Pediatric Emergency Care"},{"issue":"1","key":"10.1002\/14651858.CD006915.pub3-BIB0029|cit29","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1097\/00130478-200007000-00006","article-title":"Heliox improves ventilation during high-frequency oscillatory ventilation in pediatric patients","volume":"1","author":"Winters","year":"2000","journal-title":"Pediatric Critical Care Medicine"},{"key":"10.1002\/14651858.CD006915.pub3-BIB0030|cit30","unstructured":"ClinicalTrials.gov identifier: NCT02373683 Ongoing study February 2015"},{"issue":"4","key":"10.1002\/14651858.CD006915.pub3-BIB0031|cit31","doi-asserted-by":"crossref","first-page":"1774","DOI":"10.1542\/peds.2006-2223","article-title":"Diagnosis and management of bronchiolitis","volume":"118","author":"American Academy of","year":"2006","journal-title":"Pediatrics"},{"key":"10.1002\/14651858.CD006915.pub3-BIB0032|cit32","doi-asserted-by":"crossref","first-page":"1273","DOI":"10.1001\/jama.1936.02770420011003","article-title":"The therapeutic use of helium","volume":"107","author":"Barach","year":"1936","journal-title":"Journal of the American Medical Association"},{"issue":"1","key":"10.1002\/14651858.CD006915.pub3-BIB0033|cit33","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD009609.pub2","article-title":"High-flow nasal cannula therapy for infants with bronchiolitis","author":"Beggs","year":"2014","journal-title":"Cochrane Database of Systematic Reviews"},{"issue":"7","key":"10.1002\/14651858.CD006915.pub3-BIB0034|cit34","doi-asserted-by":"crossref","first-page":"2052","DOI":"10.1097\/01.ccm.0000084804.15352.48","article-title":"Effect of helium-oxygen (heliox) gas mixtures on the function of four pediatric ventilators","volume":"31","author":"Berkenbosch","year":"2003","journal-title":"Critical Care Medicine"},{"issue":"6","key":"10.1002\/14651858.CD006915.pub3-BIB0035|cit35","doi-asserted-by":"crossref","first-page":"865","DOI":"10.1067\/mpd.2000.110531","article-title":"Rates of hospitalization for respiratory syncytial virus infection among children in medicaid","volume":"137","author":"Boyce","year":"2000","journal-title":"Journal of Pediatrics"},{"issue":"12","key":"10.1002\/14651858.CD006915.pub3-BIB0036|cit36","doi-asserted-by":"crossref","first-page":"1649","DOI":"10.1007\/s00431-013-2094-4","article-title":"High-flow nasal cannula oxygen for bronchiolitis in a pediatric ward: a pilot study","volume":"172","author":"Bressan","year":"2013","journal-title":"European Journal of Pediatrics"},{"issue":"1","key":"10.1002\/14651858.CD006915.pub3-BIB0037|cit37","doi-asserted-by":"crossref","first-page":"e24","DOI":"10.1542\/peds.2014-2151","article-title":"Respiratory syncytial virus-associated mortality in hospitalized infants and young children","volume":"135","author":"Byington","year":"2015","journal-title":"Journal of Pediatrics"},{"issue":"7","key":"10.1002\/14651858.CD006915.pub3-BIB0038|cit38","doi-asserted-by":"crossref","first-page":"592","DOI":"10.1097\/00006454-200007000-00002","article-title":"Rehospitalization because of respiratory syncytial virus infection in premature infants younger than 33 weeks of gestation: a prospective study. IRIS Study Group","volume":"19","author":"Carbonell-Estrany","year":"2000","journal-title":"Pediatric Infectious Disease Journal"},{"issue":"5","key":"10.1002\/14651858.CD006915.pub3-BIB0039|cit39","doi-asserted-by":"crossref","first-page":"1256","DOI":"10.1378\/chest.109.5.1256","article-title":"Evaluation of heliox in children hospitalized with acute severe asthma. A randomized crossover trial","volume":"109","author":"Carter","year":"1996","journal-title":"Chest"},{"issue":"4","key":"10.1002\/14651858.CD006915.pub3-BIB0040|cit40","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1016\/j.arcped.2005.01.008","article-title":"Bronchiolitis treated with mechanical ventilation: prognosis factors and outcome in a series of 135 children","volume":"12","author":"Chevret","year":"2005","journal-title":"Archives de P\u00e9diatrie"},{"issue":"4","key":"10.1002\/14651858.CD006915.pub3-BIB0041|cit41","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1089\/jam.2004.17.299","article-title":"Development of aerosol drug delivery with helium oxygen gas mixtures","volume":"17","author":"Corcoran","year":"2004","journal-title":"Journal of Aerosol Medicine"},{"issue":"5","key":"10.1002\/14651858.CD006915.pub3-BIB0042|cit42","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1097\/01.PCC.0000128891.54799.67","article-title":"Efficacy of interventions for bronchiolitis in critically ill infants: a systematic review and meta-analysis","volume":"5","author":"Davison","year":"2004","journal-title":"Pediatric Critical Care Medicine"},{"issue":"9","key":"10.1002\/14651858.CD006915.pub3-BIB0043|cit43","doi-asserted-by":"crossref","first-page":"788","DOI":"10.1097\/INF.0b013e3181710990","article-title":"FLIP-2 Study: risk factors linked to respiratory syncytial virus infection requiring hospitalization in premature infants born in Spain at a gestational age of 32 to 35 weeks","volume":"27","author":"Figueras-Aloy","year":"2008","journal-title":"Pediatric Infectious Disease Journal"},{"issue":"7454","key":"10.1002\/14651858.CD006915.pub3-BIB0044|cit44","doi-asserted-by":"crossref","first-page":"1490","DOI":"10.1136\/bmj.328.7454.1490","article-title":"Grading quality of evidence and strength of recommendations","volume":"328","author":"GRADE Working Group","year":"2004","journal-title":"BMJ"},{"key":"10.1002\/14651858.CD006915.pub3-BIB0045|cit45","unstructured":"McMaster University (developed by Evidence Prime, Inc.) GRADEpro GDT: GRADEpro Guideline Development Tool. Available from www.gradepro.org 2015"},{"key":"10.1002\/14651858.CD006915.pub3-BIB0046|cit46","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1097\/01.PCC.0000154946.62733.94","article-title":"Heliox administration in the pediatric intensive care unit: an evidence-based review","volume":"6","author":"Gupta","year":"2005","journal-title":"Pediatric Critical Care Medicine"},{"key":"10.1002\/14651858.CD006915.pub3-BIB0047|cit47","first-page":"39","article-title":"Clinical and epidemiologic features of respiratory syncytial virus","volume":"372","author":"Hall","year":"2013","journal-title":"Current Topics in Microbiology and Immunology"},{"issue":"7414","key":"10.1002\/14651858.CD006915.pub3-BIB0048|cit48","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1136\/bmj.327.7414.557","article-title":"Measuring inconsistency in meta-analyses","volume":"327","author":"Higgins","year":"2003","journal-title":"BMJ"},{"key":"10.1002\/14651858.CD006915.pub3-BIB0049|cit49","doi-asserted-by":"crossref","first-page":"d5928","DOI":"10.1136\/bmj.d5928","article-title":"Cochrane Bias Methods Group; Cochrane Statistical Methods Group. The Cochrane Collaboration's tool for assessing risk of bias in randomised trials","volume":"343","author":"Higgins","year":"2011","journal-title":"BMJ"},{"issue":"5","key":"10.1002\/14651858.CD006915.pub3-BIB0050|cit50","doi-asserted-by":"crossref","first-page":"e214","DOI":"10.1097\/PCC.0000000000000112","article-title":"Physiologic effects of high-flow nasal cannula in infants with bronchiolitis","volume":"15","author":"Hough","year":"2014","journal-title":"Pediatric Critical Care Medicine"},{"issue":"3","key":"10.1002\/14651858.CD006915.pub3-BIB0051|cit51","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1097\/00003246-199103000-00013","article-title":"Helium-oxygen mixture in the treatment of postextubation stridor in pediatric trauma patients","volume":"19","author":"Kemper","year":"1991","journal-title":"Critical Care Medicine"},{"issue":"2","key":"10.1002\/14651858.CD006915.pub3-BIB0052|cit52","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/S0022-3476(97)70346-9","article-title":"Inhaled helium-oxygen revisited: effect of inhaled helium-oxygen during the treatment of status asthmaticus in children","volume":"130","author":"Kudukis","year":"1997","journal-title":"Journal of Pediatrics"},{"issue":"9","key":"10.1002\/14651858.CD006915.pub3-BIB0053|cit53","doi-asserted-by":"crossref","first-page":"806","DOI":"10.1097\/01.inf.0000137568.71589.bd","article-title":"The Pediatric Investigators Collaborative Network on Infections in Canada study of predictors of hospitalization for respiratory syncytial virus infection for infants born at 33 through 35 completed weeks of gestation","volume":"23","author":"Law","year":"2004","journal-title":"Pediatric Infectious Disease Journal"},{"key":"10.1002\/14651858.CD006915.pub3-BIB0054|cit54","unstructured":"Lefebvre C Manheimer E Glanville J Chapter 6: Searching for studies. In: Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 [updated March 2011]. The Cochrane Collaboration, 2011 Available from www.cochrane-handbook.org"},{"issue":"4","key":"10.1002\/14651858.CD006915.pub3-BIB0055|cit55","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1007\/s00431-002-1105-7","article-title":"Incidence and risk factors of respiratory syncytial virus-related hospitalizations in premature infants in Germany","volume":"162","author":"Liese","year":"2003","journal-title":"European Journal of Pediatrics"},{"issue":"6","key":"10.1002\/14651858.CD006915.pub3-BIB0056|cit56","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1542\/peds.79.6.939","article-title":"Wheezing in infants: the response to epinephrine","volume":"76","author":"Lowell","year":"1987","journal-title":"Pediatrics"},{"issue":"8","key":"10.1002\/14651858.CD006915.pub3-BIB0057|cit57","first-page":"769","article-title":"Prospective multicenter study of viral etiology and hospital length of stay in children with severe bronchiolitis","volume":"166","author":"Mansbach","year":"2012","journal-title":"Archives of Pediatrics and Adolescent Medicine"},{"issue":"2","key":"10.1002\/14651858.CD006915.pub3-BIB0058|cit58","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.1016\/j.jcrc.2011.05.029","article-title":"Noninvasive ventilation with helium-oxygen in children","volume":"27","author":"Martinon-Torres","year":"2012","journal-title":"Journal of Critical Care"},{"issue":"1","key":"10.1002\/14651858.CD006915.pub3-BIB0059|cit59","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/S2213-2600(14)70314-5","article-title":"What's weighing down heliox?","volume":"3","author":"Martin\u00f3n-Torres","year":"2015","journal-title":"Lancet Respiratory Medicine"},{"issue":"5","key":"10.1002\/14651858.CD006915.pub3-BIB0060|cit60","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1111\/jpc.12509","article-title":"High-flow nasal cannula oxygen therapy for infants with bronchiolitis: pilot study","volume":"50","author":"Mayfield","year":"2014","journal-title":"Journal of Paediatrics and Children Health"},{"key":"10.1002\/14651858.CD006915.pub3-BIB0061|cit61","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1016\/j.jpeds.2009.10.039","article-title":"High flow nasal cannulae therapy in infants with bronchiolitis","volume":"156","author":"McKiernan","year":"2010","journal-title":"Journal of Pediatrics"},{"issue":"12","key":"10.1002\/14651858.CD006915.pub3-BIB0062|cit62","doi-asserted-by":"crossref","first-page":"1357","DOI":"10.1097\/00003246-199012000-00009","article-title":"Does prematurity alter the course of respiratory syncytial virus infection?","volume":"18","author":"Meert","year":"1990","journal-title":"Critical Care Medicine"},{"issue":"6","key":"10.1002\/14651858.CD006915.pub3-BIB0063|cit63","doi-asserted-by":"crossref","first-page":"1088","DOI":"10.1007\/s00134-013-2879-y","article-title":"Is treatment with a high flow nasal cannula effective in acute viral bronchiolitis? A physiologic study","volume":"39","author":"Mil\u00e9si","year":"2013","journal-title":"Intensive Care Medicine"},{"issue":"9725","key":"10.1002\/14651858.CD006915.pub3-BIB0064|cit64","doi-asserted-by":"crossref","first-page":"1545","DOI":"10.1016\/S0140-6736(10)60206-1","article-title":"Global burden of acute lower respiratory infections due to respiratory syncytial virus in young children: a systematic review and meta-analysis","volume":"375","author":"Nair","year":"2010","journal-title":"Lancet"},{"issue":"Suppl","key":"10.1002\/14651858.CD006915.pub3-BIB0065|cit65","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1097\/01.inf.0000053890.66801.97","article-title":"Respiratory syncytial virus bronchiolitis: supportive care and therapies designed to overcome airway obstruction","volume":"22","author":"Panitch","year":"2003","journal-title":"Pediatric Infectious Disease Journal"},{"issue":"Suppl 1","key":"10.1002\/14651858.CD006915.pub3-BIB0066|cit66","first-page":"21","article-title":"Pathophysiological mechanisms for the respiratory syncytial virus-reactive airway disease link","volume":"3","author":"Piedimonte","year":"2002","journal-title":"Respiratory Research"},{"issue":"3 Pt 1","key":"10.1002\/14651858.CD006915.pub3-BIB0067|cit67","first-page":"629","article-title":"Admission to the intensive care unit for respiratory syncytial virus bronchiolitis: a national survey before palivizumab use","volume":"113","author":"Prais","year":"2004","journal-title":"Pediatrics"},{"issue":"5","key":"10.1002\/14651858.CD006915.pub3-BIB0068|cit68","doi-asserted-by":"crossref","first-page":"728","DOI":"10.1016\/j.jpeds.2009.04.063","article-title":"Incidence of apnea in infants hospitalized with respiratory syncytial virus bronchiolitis: a systematic review","volume":"155","author":"Ralston","year":"2009","journal-title":"Journal of Pediatrics"},{"key":"10.1002\/14651858.CD006915.pub3-BIB0069|cit69","unstructured":"The Nordic Cochrane Centre, The Cochrane Collaboration Review Manager (RevMan) 2014"},{"key":"10.1002\/14651858.CD006915.pub3-BIB0070|cit70","doi-asserted-by":"crossref","first-page":"1787","DOI":"10.1007\/s00134-011-2355-5","article-title":"Delivery of helium oxygen mixture during spontaneous breathing: evaluation of three high-concentration face masks","volume":"37","author":"Roche-Campo","year":"2011","journal-title":"Intensive Care Medicine"},{"issue":"10","key":"10.1002\/14651858.CD006915.pub3-BIB0071|cit71","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD002884.pub2","article-title":"Heliox for non-intubated acute asthma patients","author":"Rodrigo","year":"2010","journal-title":"Cochrane Database of Systematic Reviews"},{"key":"10.1002\/14651858.CD006915.pub3-BIB0072|cit72","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1007\/s00134-011-2177-5","article-title":"Reduced intubation rates for infants after introduction of high-flow nasal prong oxygen delivery","volume":"37","author":"Schibler","year":"2011","journal-title":"Intensive Care Medicine"},{"issue":"5 Suppl","key":"10.1002\/14651858.CD006915.pub3-BIB0073|cit73","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1067\/S0022-3476(03)00511-0","article-title":"Environmental and demographic risk factors for respiratory syncytial virus lower respiratory tract disease","volume":"143","author":"Simoes","year":"2003","journal-title":"Journal of Pediatrics"},{"issue":"24","key":"10.1002\/14651858.CD006915.pub3-BIB0074|cit74","doi-asserted-by":"crossref","first-page":"2286","DOI":"10.1056\/NEJMoa1301839","article-title":"Racemic adrenaline and inhalation strategies in acute bronchiolitis","volume":"368","author":"Skjerven","year":"2013","journal-title":"New England Journal of Medicine"},{"issue":"8","key":"10.1002\/14651858.CD006915.pub3-BIB0075|cit75","doi-asserted-by":"crossref","first-page":"1469","DOI":"10.1007\/s00134-008-1064-1","article-title":"Room air dilution of heliox given by facemask","volume":"34","author":"Standley","year":"2008","journal-title":"Intensive Care Medicine"},{"issue":"6","key":"10.1002\/14651858.CD006915.pub3-BIB0076|cit76","doi-asserted-by":"crossref","first-page":"1222","DOI":"10.1378\/chest.95.6.1222","article-title":"Effectiveness of open-circuit and oxyhood delivery of helium-oxygen","volume":"95","author":"Stillwell","year":"1989","journal-title":"Chest"},{"issue":"2","key":"10.1002\/14651858.CD006915.pub3-BIB0077|cit77","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1016\/S0022-3476(95)70547-3","article-title":"Pediatric Investigators Collaborative Network on Infections in Canada (PICNIC) prospective study of risk factors and outcomes in patients hospitalized with respiratory syncytial viral lower respiratory tract infection","volume":"126","author":"Wang","year":"1995","journal-title":"Journal of Pediatrics"},{"issue":"6","key":"10.1002\/14651858.CD006915.pub3-BIB0078|cit78","doi-asserted-by":"crossref","first-page":"E96","DOI":"10.1542\/peds.107.6.e96","article-title":"A randomized comparison of helium-oxygen mixture (Heliox) and racemic epinephrine for the treatment of moderate to severe croup","volume":"107","author":"Weber","year":"2001","journal-title":"Pediatrics"},{"issue":"Suppl","key":"10.1002\/14651858.CD006915.pub3-BIB0079|cit79","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1067\/S0022-3476(03)00508-0","article-title":"Review of epidemiology and clinical risk factors for severe respiratory syncytial virus (RSV) infection","volume":"143","author":"Welliver","year":"2003","journal-title":"Journal of Pediatrics"},{"issue":"5","key":"10.1002\/14651858.CD006915.pub3-BIB0080|cit80","doi-asserted-by":"crossref","first-page":"752","DOI":"10.1016\/S0022-3476(84)80961-0","article-title":"Mechanics and energetics of breathing helium in infants with bronchopulmonary dysplasia","volume":"104","author":"Wolfson","year":"1984","journal-title":"Journal of Pediatrics"},{"issue":"3","key":"10.1002\/14651858.CD006915.pub3-BIB0081|cit81","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1001\/archpedi.1972.02110090097011","article-title":"A clinical scoring system for the diagnosis of respiratory failure. Preliminary report on childhood status asthmaticus","volume":"123","author":"Wood","year":"1972","journal-title":"American Journal of Diseases of Children"},{"issue":"7","key":"10.1002\/14651858.CD006915.pub3-BIB0082|cit82","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD006458.pub2","article-title":"Nebulised hypertonic saline solution for acute bronchiolitis in infants","author":"Zhang","year":"2013","journal-title":"Cochrane Database of Systematic Reviews"},{"issue":"1","key":"10.1002\/14651858.CD006915.pub3-BIB0083|cit83","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD006915","article-title":"Heliox inhalation therapy for bronchiolitis in infants","author":"Liet","year":"2008","journal-title":"Cochrane Database of Systematic Reviews"},{"issue":"4","key":"10.1002\/14651858.CD006915.pub3-BIB0084|cit84","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD006915.pub2","article-title":"Heliox inhalation therapy for bronchiolitis in infants","author":"Liet","year":"2010","journal-title":"Cochrane Database of Systematic Reviews"}],"container-title":["Cochrane Database of Systematic Reviews"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full\/10.1002\/14651858.CD006915.pub3","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,11]],"date-time":"2024-06-11T06:17:20Z","timestamp":1718086640000},"score":1,"resource":{"primary":{"URL":"http:\/\/doi.wiley.com\/10.1002\/14651858.CD006915.pub3"}},"subtitle":[],"editor":[{"name":"Cochrane Acute Respiratory Infections Group","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2015,9,18]]},"references-count":84,"journal-issue":{"issue":"9","published-online":{"date-parts":[[2015,9]]}},"URL":"https:\/\/doi.org\/10.1002\/14651858.cd006915.pub3","relation":{},"ISSN":["1465-1858"],"issn-type":[{"value":"1465-1858","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,9,18]]}}}